Originalpublikationen

Tilki D, Kilic E, Tauber R, Pfeiffer D, Stief CG, Tauber R, Ergün S.
The complex structure of the smooth muscle layer of spermatic veins and
its potential role in the development of varicocele testis.
Eur Urol. (in press) (2006)

Zengin E, Chalajour F, Gehling UM, Ito WD, Treede H, Lauke H, Weil J, Reichenspurner H, Kilic N, and Ergün S.
Vascular wall resident progenitor cells: a source for postnatal vasculogenesis.
Development 133, 1543-1551, (2006).

Hansen-Algensteadt N, Algensteadt P, Hamann A, Wolfram L, Cingöz G, Schäfer C, Schwarzloh B, Kilic N, Greten H, Rüther W, Ergün S.
Neural driven angiogenesis by overexpression of nerve growth factor.
Histochem. Cell Biol. (2006).

Tilki D, Irmak S, Oliveira-Ferrer L, Hauschild J, Miethe K, Atakaya H, Hammerer P, Friedrich MG, Schuch G, Galalae R, Stief CG, Kilic E, Huland H, and Ergün S.
CEA-related cell adhesion molecule-1 is involved in angiogenic switch in prostate cancer.
Oncogene (2006).

Muhlhausen C, Ott N, Chalajour F, Tilki D, Freudenberg F, Shahhossini M, Thiem J, Ullrich K, Braulke T, and Ergün S.
Endothelial effects of 3-hydroxyglutaric acid: implications for glutaric aciduria type I.
Pediatr. Res. 59, 196-202 (2006).

Ergün S, Tilki D, Oliveira-Ferrer L, Schuch G, Kilic N.
Significance of vascular stabilization for tumor growth and metastasis.
Cancer Letters (2006).

Irmak S, Tilki D, Heukeshoven J, Oliveira-Ferrer L, Friedrich M, Huland H, and Ergün S.
Stage-dependent increase of orosomucoid and zinc-alpha(2)-glycoprotein
in urinary bladder cancer.
Proteomics. 5, 4296-4304 (2005).

Schuch G, Oliveira-Ferrer L, Loges S, Laack E, Bokemeyer C, Hossfeld DK, Fiedler W, Ergün S.
Antiangiogenic treatment with endostatin inhibits progression of AML in vivo.
Leukemia, 19: 1312-1317 (2005).

Kilic N, Ferrer-Oliveira L, Loges S, Chalajour F, Weil J, Fernando M, Ergün S.
Pro-angiogenic signaling by endothelial presence of CEA-related cell adhesion
molecule-1 (CEACAM1).
J Biol Chem, 280: 2361-2369 (2005).

Mühlhausen C, Ergün S, Strauss KA, Koeller DM, Crnic L, Woontner M, Goodman SI, Ullrich K, Braulke T.
Vascular Dysfunction as an additional pathomechanism
in glutaric aciduria type I.
J. Inherit. Metab. Dis. 27: 829-834 (2004).

Oliveira-Ferrer L, Tilki D, Ziegeler G, Hauschild J, Loges S, Irmak S, Huland H,
Friedrich M, Ergün S.
Dual Role of CEACAM1 in Angiogenesis and Invasion of Human Urinary Bladder.
Cancer Res, 64: 8932-8938 (2004).

Loges S, Fehse B, Brockmann MA, Lamszus K, Butzal M, Guckenbiehl M, Schuch G, Ergün S, Fischer U, Zander AR, Hossfeld D, Fiedler W, Gehling UM.
Identification of the adult human hemangioblast.
Stem Cells Dev 13: 229-242 (2004).

Ergün S, Buschmann C, Lauke H, Chalajour F, Kilic N, Strätling WH, Schumann GG.
Cell type-specific expression of LINE-1 ORF1 and ORF2 in human embryonic and adult tissues.
J Biol Chem, 279: 27753-27763 (2004).

Chalajour F, Treede H, Ebrahimnejad A, Lauke H, Reichenspurner H, Ergün S.
Angiogenic Activation of Valvular Endothelial Cells in Aortic Valve Stenosis.
Exp Cell Res 298: 455-464 (2004)

Lauke H, Kilic N, Bozorgzad R, Fernando M, Neshat-Vahid S, Pottek T, Ergün S.
Expression of CEA-related cell adhesion molecule-1 (CEACAM1) in normal human Sertoli cells and its up-regulation in impaired spermatogenesis.
Mol. Hum. Reprod.10: 247-257 (2004).

Benndorf R, Boger RH, Ergün S, Steenpass A, Wieland T.
Angiotensin II type 2 receptor inhibits VEGF-induced migration and tube formation of human endothelial cells.
Circ. Res. 93: 438-447 (2003).

Dührsen U, Martinez T, Vohvinkel G, Ergün S, Sun L, McMahon G, Döring J, Hossfeld DK, Fiedler W.
Effects of vascular endothelial and platelet-derived growth factor receptor inhibitors on long-term cultures from normal human bone marrow cultures.
Growth Factors 19: 1-17 (2001).

Ergün S, Kilic N, Wurmbach JH, Ebrahimnejad A, Fernando M, Sevinc S, Kilic E, Fiedler W, Lauke H, Lamszus K, Hammerer P, Weil J, Herbst H, Folkman J.
Endostatin inhibits angiogenesis by stabilization of newly formed endothelial tubes.
Angiogenesis, 4:193-206 (2001).

Wurmbach JH, Hammerer P, Sevinc S, Huland H, Ergün S.
The expression of angiopoietins and their receptor tie-2 in human prostate carcinoma.
Anticancer Research 20: 5217-5220 (2001).

Fink C, Ergün S, Kralisch D, Remmers U, Weil J, Eschenhagen T.
Chronik stretch of engineered heart tissue induces hyperthrophy and functional improvement.
FASEB 14: 669-679 (2000).

Gehling UM, Ergün S, Schumacher U, Wagener C, Pantel K, Otte M, Schuch G, Schafhausen P, Mende T, Kilic N, Kluge K, Schäfer B, Hossfeld DK, Fiedler W.
In vitro differentiation of endothelial cells from AC133-positive progenitor cells.
Blood 95:3106-3112 (2000).

Lamszus K, Lengler U, Schmidt NO, Stavrou D, Ergün S, Westphal M.
Vascular endothelial growth, placenta growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human meningiomas and their relation to angiogenesis and malignancy.
Neurosurgery 46: 938-947 (2000).

Fiedler W, Henke RP, Ergün S, Schumacher U, Gehling UM, Vohwinkel G, Kilic N, Hossfeld DK.
Derivation of a new hematopoietic cell line with endothelial features from a patient with transformed myeloproliferative syndrome: a case report
Cancer 88:344-351 (2000).

Ergün S, Kilic N, Ziegeler G, Hansen, Nollau P, Götze J, Wurmbach JH, Horst A, Weil J, Fernando M, Wagener C.
CEA-related cell adhesion molecule 1: a potent angiogenic factor and a major effector of vascular endothelial growth factor.
Mol Cell 5:311-320 (2000).

Kilic N, Lauke H, Fiedler W, Pottek T, Kilic E, Freeman MR, Ergün S.
Angiogenic switch and vascular stability in human Leydig cell tumors.
Angiogenesis 3: 231-240 (1999).

Greaven U, Fiedler W, Karpinski S, Ergün S, Kilic N, Rodeck U, Schmiegel W, Hossfeld DK.
Melanoma-associated expression of vascular endothelial growth factor
and its receptors Flt-1 and KDR.
J Cancer Res Clin Oncol 125:621-629 (1999).

Lamszus K, Schmidt NO, Ergün S, Westphal M.
Isolation and culture of human neuromicrovascular endothelial cells for the study of angiogenesis in vitro.
J Neurosci Res 55:370-81 (1999).

Ergün S, Harneit S, Paust HJ, Mukhopadhyay A, Holstein AF.
Endothelin and endothelin receptors A and B in the human testis.
Anat Embryol 199:207-214 (1999).

Schmidt NO, Westphal M, Hagel C, Ergün S, Stavrou D, Rosen EM, Lamszus K.
Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis.
Int J Cancer 84:10-18 (1999).

Bamberger CM, Wald M, Bamberger AM, Ergün S, Beil FU, Schulte HM.
Human lymphocytes produce urocortin, but not corticotropin-releasing hormone.
J Clin Endocrinol Metab 83(2):708-711 (1998).

Ergün S, Luttmer W, Fiedler W, Holstein AF.
Functional expression and localization.of vascular endothelial growth factor (VEGF) and its receptors in the human epididymis.
Biol Reprod 58(1):160-168 (1998).

Ungefroren H, Ivell R, Ergün S.
Region specific expression of androgen receptor in the human epididymis.
Mol Hum Reprod 3(11):933-940 (1997).

Fiedler W, Greven U, Ergün S, Verago S, Kilic N, Stockschläder M, Hossfeld K.D.
Expression of FLT4 and its ligand VEGF-C in acute myeloid leukemia.
Leukemia, 11(8):1234-1237 (1997).

Ergün S, Ungefroren H, Holstein AF, Davidoff MS.
Estrogen and progesterone receptors and estrogen receptor-related antigen (ER-D5) in human epididymis.
Mol Reprod Dev 47(4):448-455 (1997).

Ergün S, Kilic N, Fiedler W, Mukhopadhyay AK.
Vascular endothelial growth factor and its receptors in normal human testicular tissue.
Mol Cell Endocrinol 131(1):9-20 (1997).

Harneit S, Paust HJ, Mukhopadhyay AK, Ergün S.
Localization of endothelin-1 and endothelin-receptors A and B in human epididymis.
Mol Human Reprod 3(7):579-584 (1997).

Ergün S, Bruns T, Soyka A, Tauber R.
Angioarchitecture of the human spermatic cord.
Cell Tissue Res 288(2):391-398 (1997).

Fiedler W, Graeven U, Ergün S, Verago S, Kilic N, Stockschläder M, Hossfeld DK.
Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia.
Blood 89(6):1870-1875 (1997).

Bruns T, Born O, Ergün S, Tauber R.
Die antegrade skrotale Phlebographie der V. spermatica bei linksseitiger Varikozele testis - sind retrograde Phlebographieklassifikationen für die Typisierung geeignet?
Rö-Fortsch Geb Röntgenstr Neuen Bildgeb Verfahr 166(1):44-50 (1997).

Bruns T, Ergün S, Born O, Tauber R.
Skrotale Spermaticaphlebographie bei linksseitiger idiopathischer Varicocele testis - die Bedeutung der Gefäßvariationen für die antegrade Sklerosierung.
Aktuelle Urologie 27(5):299-305 (1996).

Ergün S, Bruns T, Tauber R.
Die vaskuläre Organisation des Plexus pampiniformis beim Mann und ihre Bedeutung bei der antegraden Sklerosierung der Varicocele testis. Urologe A 35(6):463-467 (1996).

Ergün S, Davidoff MS, Holstein AF.
Capillaries in the lamina propria of human seminiferous tubules are partly fenestrated.
Cell Tissue Res 286(1):93-102 (1996).

Walther N, Jansen M, Ergün S, Kascheike B, Ivell R.
Sertoli cell lines established from H-2Kb-tsA58 transgenic mice differentially regulate
the expression of cell-specific genes.
Exp Cell Res 225(2):411-421 (1996).

Ungefroren H, Ergün S, Krull N, Holstein AF.
Expression of the small proteoglycans biglycan and decorin in the adult human testis.
Biol Reprod 52(5):1095-1105 (1995).

Ergün S, Stingl J, Holstein AF.
Microvasculature of the human testis in correlation to Leydig cells and seminiferous tubules.
Andrologia 26(5):255-262 (1994).

Ergün S, Stingl J, Holstein AF.
Segmental angioarchitecture of the testicular lobule in man.
Andrologia 26(3):143-153 (1994).

Übersichtsarbeiten

Ergün S, Zengin E, Tilki D, Weil J, Kilic N.
Functional Implications of Vascular Wall Resident Endothelial Precursor Cells
(Atherosclerosis) (2007).

Ergün S.
Inverse signalling of CEACAM1 in tumor angiogenesis.
Invited review, Cancer Letters (in preparation, 2007) 3.

Ergün S
Mechanisms of vascular stabilization in tumors
(in preparation, 2007)

Ergün S, Tilki D, Oliveira-Ferrer L, Schuch G, Kilic N.
Significance of vascular stabilization for tumor growth and metastasis.
Cancer Letters, (2006).

Wagener C, Ergün S.
Angiogenic Properties of Carcinomembryonic Antigen-Related Cell Adhesion Molecule 1.
Exp Cell Res, 19-24 (2000).

Ergün S, Kilic N, Harneit S, Paust HJ, Ungefroren H, Mukhopadhyay A, Davidoff M, Holstein AF.
Microcirculation and the vascular control of the testis.
Adv Exp Med Biol 424:163-180 (1997).

Walther N, Jansen M, Ergün S, Kascheike B, Tillmann G, Ivell R.
Sertoli cell-specific gene expression in conditionally immortalized cell lines.
Adv Exp Med Biol 424:139-142 (1997).

Haider SG, Kilic N, Ergün S.
Functional markers for fetal and postnatal differentiation of rat Leydig cells.
Adv Exp Med Biol 424:143-144 (1997).

Ergün S, Kilic N, Harneit S, Paust HJ, Ungefroren H, Mukhopadhyay A, Davidoff M, Holstein AF.
Microcirculation and the vascular control of the testis.
Adv Exp Med Biol 424:163-180 (1997).

Kilic N, Ergün S, Fiedler W, Holstein AF.
Capillarization and expression of VEGF and its receptors in Leydig cell tumors of the human testis.
Adv Exp Med Biol 424:181-182 (1997).

Bruns T, Ergün S, Tauber R.
Morphological and functional aspects of the human spermatic cord veins.
Adv Exp Med Biol 424:185-186 (1997).

Ergün S, Bruns T, Tauber R.
Angioarchitecture of the human spermatic cord.
Adv Exp Med Biol 424:183-184 (1997).

Buchbeiträge

Ergün S, Tilki D, Kilic N.
Vascular Stabilization.
Encyclopedia of Cancer, (in press) (2007)

Kilic N, Ergün S.
Methods to evaluate the formation and stabilization of blood vessels and their role in tumor growth and metastasis.
In: Methods in Molecular Medicine, Vol. 58: Metastasis Research Protocols,
Vol. 2: Cell Behaviour In Vitro and In Vivo.
Eds: S. A. Brooks and U. Schumacher.
Humana Press Inc., Totowa, NJ: pp 125-148 (2001).