2011
Frede S, Freitag P, Geuting L, Konietzny R, Fandrey J.
Oxygen-regulated expression of the erythropoietin gene in a human renal cell line REPC.
Blood 2011 Mar 15.
Schenk U, Frascoli M, Proietti M, Geffers R, Traggiai E, Buer J, et. al.
ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors.
Sci Signal. 2011 Mar 1.
Ruhl M, Knuschke T, Schewior K, Glavinic L, Neumann-Haefelin C, Chang DI, et. al.
The CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural Proteins.
Gastroenterology. 2011 Mar 1.
Connolly SJ, Eikelboom J, Joyner C, Diener HC, Hart R, Golitsyn S, et. al.
Apixaban in Patients with Atrial Fibrillation.
N Engl J Med 2011 Feb 10.
Zhang Y, Li X, Carpinteiro A, Goettel JA, Soddemann M, Gulbins E.
Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections.
Nat Med 2011 feb 6.
Dietze KK, Zelinskyy G, Gibbert K, Schimmer S, Francois S, Myers L, et. al.
Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points.
Proc Natl Acad Sci U S A. 2011 Jan 24.
2010
- Januar
Kahraman A, Schlattjan M, Kocabayoglu P, Yildiz-Meziletoglu S, Schlensak M, Fingas CD, et. al.
Major histocompatibility complex class I-related chains A and B (MIC A/B): a novel role in nonalcoholic steatohepatitis.
Hepatology2010 Jan.
- Februar
Kahlert P, Knipp SC, Schlamann M, Thielmann M, Al-Rashid F, Weber M, et. al.
Silent and apparent cerebral ischemia after percutaneous transfemoral aortic valve implantation: a diffusion-weighted magnetic resonance imaging study.
Circulation.2010 Feb 23.
- März
Wohlschlaeger J, Levkau B, Brockhoff G, Schmitz KJ, von Winterfeld M, Takeda A, et. al.
Hemodynamic support by left ventricular assist devices reduces cardiomyocyte DNA content in the failing human heart.
Circulation2010 Mar 2.
Resistance to antiangiogenic therapy is directed by vascular phenotype, vessel stabilization, and maturation in malignant melanoma.
J Exp Med.2010 Mar 15.
- Mai
Rottlaender D, Boengler K, Wolny M, Michels G, Endres-Becker J, Motloch LJ, et. al.
Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial KATP channels in mouse cardiomyocytes.
J Clin Invest.2010 May 3.
- Juli
Wüstehube J, Bartol A, Liebler SS, Brütsch R, Zhu Y, Felbor U, Sure U, Augustin HG, Fischer A.
Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling.
Proc Natl Acad Sci U S A 2010 Jul 13Stanelle J, Döring C, Hansmann ML, Küppers R.
Mechanisms of aberrant GATA3 expression in classical Hodgkin lymphoma and its consequences for the cytokine profile of Hodgkin and Reed/Sternberg cells.
Blood 2010 Jul 26Herbst RS, Sun Y, Eberhardt WE, Germonpré P, Saijo N, Zhou C, et. al.
Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial.
Lancet Oncol. 2010 Jul 11
- August
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et. al.
Improved survival with ipilimumab in patients with metastatic melanoma.
N Engl J Med.2010 Aug 13.
- September
Dechêne A, Sowa JP, Gieseler RK, Jochum C, Bechmann LP, El Fouly A, et. al.
Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation.
Hepatology.2010 Sep.du Bois A, Herrstedt J, Hardy-Bessard AC, Müller HH, Harter P, Kristensen G, et. al.
Phase III trial of carboplatin plus paclitaxel with or without gemcitabine in first-line treatment of epithelial ovarian cancer.
J Clin Oncol.2010 Sep.20
- Oktober
Elsenbruch S, Rosenberger C, Bingel U, Forsting M, Schedlowski M, Gizewski ER.
Patients with irritable bowel syndrome have altered emotional modulation of neural responses to visceral stimuli.
Gastroenterology 2010 OctElAli A, Hermann DM.
Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain.
Sci Signal. 2010 Oct 5
- November
Endele S, Rosenberger G, Geider K, Popp B, Tamer C, Stefanova I, et. al.
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes
Nat Genet. 2010 Nov.Diener HC, Connolly SJ, Ezekowitz MD, Wallentin L, Reilly PA, Yang S, et. al.
Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial.
Lancet Neurol. 2010 Nov 6.
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU et. al.
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
Pain. 2010 Nov.Hilgard P, Hamami M, Fouly AE, Scherag A, Müller S, Ertle J, Heusner T, Cicinnati VR, Paul A, Bockisch A, Gerken G, Antoch G.
Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and long-term survival.
Hepatology. 2010 Nov.
- Dezember
Johannes G. Dawerse, Jill Dixon, Saskia Seland, Claudia A L Ruivenkamp, Arie van Haeringen, Lies H Hoefsloot, et. al.
Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome
Nat Gen. 2010 Dez 5.
2009
- Januar
Skyschally A, van Caster P, Boengler K, Gres P, Musiolik J, Schilawa D, Schulz R, Heusch G.
Ischemic postconditioning in pigs: no causal role for RISK activation.
Circ Res.2009 Jan 2.
- Februar
Westendorf AM, Fleissner D, Groebe L, Jung S, Gruber AD, Hansen W, Buer J.
CD4+Foxp3+ regulatory T cell expansion induced by antigen-driven interaction with intestinal epithelial cells independent of local dendritic cells.
Gut.2009 Feb.Markova B, Albers C, Breitenbuecher F, Melo JV, Brümmendorf TH, Heidel F, Lipka D, Duyster J, Huber C, Fischer T.
Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.
Oncogene.2009 Feb 4.Stahl M, Walz MK, Stuschke M, Lehmann N, Meyer HJ, Riera-Knorrenschild J, et. al.
Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction.
J Clin Oncol.2009 Feb 20.
- April
Pfeufer A, Sanna S, Arking DE, Müller M, Gateva V, Fuchsberger C, et. al.
Common variants at ten loci modulate the QT interval duration in the QTSCD Study.
Nat Genet.2009 Apr.
- Mai
Schmitz R, Hansmann ML, Bohle V, Martin-Subero JI, Hartmann S, Mechtersheimer G, et. al.
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma.
J Exp Med2009 May 11.Frede S, Stockmann C, Winning S, Freitag P, Fandrey J.
Hypoxia-inducible factor (HIF) 1alpha accumulation and HIF target gene expression are impaired after induction of endotoxin tolerance.
J Immunol.2009 May 15.
- Juli
Podolsky DK, Gerken G, Eyking A, Cario E.
Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency.
Gastroenterology.2009 Jul.
- August
Zelinskyy G, Dietze K, Sparwasser T, Dittmer U.
Regulatory T cells suppress antiviral immune responses and increase viral loads during acute infection with a lymphotropic retrovirus.
PLoS Pathog2009 Aug.Ey B, Eyking A, Gerken G, Podolsky DK, Cario E.
TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury.
J Biol Chem.2009 Aug 14.
- September
Mühlenberg T, Zhang Y, Wagner AJ, Grabellus F, Bradner J, Taeger G, Lang H, Taguchi T, Schuler M, Fletcher JA, Bauer S.
Inhibitors of deacetylases suppress oncogenic KIT signaling, acetylate HSP90, and induce apoptosis in gastrointestinal stromal tumors.
Cancer Res.2009 Sep 1.Eggebrecht H, Thompson M, Rousseau H, Czerny M, Lönn L, Mehta RH, et. al.
Retrograde ascending aortic dissection during or after thoracic aortic stent graft placement: insight from the European registry on endovascular aortic repair complications.
Circulation.2009 Sep 15.
- Oktober
Zelinskyy G, Dietze KK, Hüsecken YP, Schimmer S, Nair S, Werner T, et. al.
The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response.
Blood.2009 Oct 8.
- November
Seifert M, Küppers R.
Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+ B cells and the dynamics of memory B cell generation.
J Exp Med.2009 Nov 23.
- Dezember
Wang B, Trippler M, Pei R, Lu M, Broering R, Gerken G, Schlaak JF.
Toll-like receptor activated human and murine hepatic stellate cells are potent regulators of hepatitis C virus replication.
J Hepatol.2009 Dez.
