Publikationen

Zeitschriften und Buchbeiträge

 

2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1991 1990 1989


2009

  • Welge V, Fiege O, Lewczuk P, Mollenhauer B, Esselmann H, Klafki HW, Wolf S, Trenkwalder C, Otto M, Kornhuber J, Wiltfang J, Bibl M. Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease. J Neural Transm. 2009 Feb;116(2):203-12.
  • Weih M, Abu-Omar K, Esselmann H, Gelbrich G, Lewczuk P, Rutten A, Wiltfang J, Kornhuber J. [Physical activity and prevention of Alzheimer's dementia: current evidence and feasibility of an interventional trial]. Fortschr Neurol Psychiatr. 2009 Mar;77(3):146-51.
  • Verwey NA, van der Flier WM, Blennow K, Clark C, Sokolow S, De Deyn PP, Galasko D, Hampel H, Hartmann T, Kapaki E, Lannfelt L, Mehta PD, Parnetti L, Petzold A, Pirttila T, Saleh L, Skinningsrud A, Swieten JC, Verbeek MM, Wiltfang J, Younkin S, Scheltens P, Blankenstein MA. A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease. Ann Clin Biochem. 2009 May;46(Pt 3):235-40.
  • Serneels L, Van Biervliet J, Craessaerts K, Dejaegere T, Horre K, Van Houtvin T, Esselmann H, Paul S, Schafer MK, Berezovska O, Hyman BT, Sprangers B, Sciot R, Moons L, Jucker M, Yang Z, May PC, Karran E, Wiltfang J, D'Hooge R, De Strooper B. gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease. Science. 2009 May 1;324(5927):639-42.
  • Maler JM, Spitzer P, Klafki HW, Esselmann H, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Distinct fractional Abeta release patterns in human mononuclear phagocytes. J Neuroimmunol. 2009 Jan 3;206(1-2):1-4.
  • Leuchtenberger S, Maler J, Czirr E, Ness J, Lichtenthaler SF, Esselmann H, Pietrzik CU, Wiltfang J, Weggen S. Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein. Neurodegener Dis. 2009;6(1-2):1-8.
  • Kornhuber J, Terfloth L, Bleich S, Wiltfang J, Rupprecht R. Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors. Eur J Med Chem. 2009 Jun;44(6):2667-72.
  • Kornhuber J, Schmidtke K, Frolich L, Perneczky R, Wolf S, Hampel H, Jessen F, Heuser I, Peters O, Weih M, Jahn H, Luckhaus C, Hull M, Gertz HJ, Schroder J, Pantel J, Rienhoff O, Seuchter SA, Ruther E, Henn F, Maier W, Wiltfang J. Early and Differential Diagnosis of Dementia and Mild Cognitive Impairment. Design and Cohort Baseline Characteristics of the German Dementia Competence Network. Dement Geriatr Cogn Disord. 2009 Apr 1;27(5):404-17.
  • Kolsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Teipel SJ, Kornhuber J, Frolich L, Heuser I, Peters O, Wiese B, Kaduszkiewicz H, van den Bussche H, Hull M, Kurz A, Ruther E, Henn FA, Maier W. Association of SORL1 gene variants with Alzheimer's disease. Brain Res. 2009 Feb 3.
  • Jessen F, Gur O, Block W, Ende G, Frolich L, Hammen T, Wiltfang J, Kucinski T, Jahn H, Heun R, Maier W, Kolsch H, Kornhuber J, Traber F. A multicenter (1)H-MRS study of the medial temporal lobe in AD and MCI. Neurology. 2009 May 19;72(20):1735-40.
  • Bonnet U, Specka M, Hamzavi Abedi R, Wiltfang J, Scherbaum N. Severe protracted alcohol withdrawal syndrome: prevalence and pharmacological treatment at an inpatient detoxification unit--a naturalistic study. Pharmacopsychiatry. 2009 Mar;42(2):76-8.
  • Bonnet U, Schafer M, Richter C, Milkereit J, Wiltfang J, Scherbaum N, Lieb B. [Anticonvulsants in the treatment of alcoholism]. Fortschr Neurol Psychiatr. 2009 Apr;77(4):192-202.
  • Blennow K, De Meyer G, Hansson O, Minthon L, Wallin A, Zetterberg H, Lewczuk P, Vanderstichele H, Vanmechelen E, Kornhuber J, Wiltfang J. Evolution of Abeta42 and Abeta40 Levels and Abeta42/Abeta40 Ratio in Plasma during Progression of Alzheimer's Disease: A Multicenter Assessment. J Nutr Health Aging. 2009 Mar;13(3):205-8.
  • Alexopoulos P, Gunther F, Popp J, Jessen F, Peters O, Wolf S, Kneib T, Kurz A, Richter-Schmidinger T, Lewczuk P, Bleich S, Wiltfang J, Kornhuber J. Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia. J Am Geriatr Soc. 2009 Apr;57(4):737-9.


2008

  • Svitek J, Heberlein A, Bleich S, Wiltfang J, Kornhuber J, Hillemacher T. Extensive craving in high dose zolpidem dependency. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):591-2.
  • Smirnov A, Trupp A, Henkel AW, Bloch E, Reulbach U, Lewczuk P, Riggert J, Kornhuber J, Wiltfang J. Differential processing and secretion of Abeta peptides and sAPPalpha in human platelets is regulated by thrombin and prostaglandine 2. Neurobiol Aging. 2008 Feb 4.
  • Otto M, Lewczuk P, Wiltfang J. Neurochemical approaches of cerebrospinal fluid diagnostics in neurodegenerative diseases. Methods. 2008 Apr;44(4):289-98.
  • Mamo JC, Jian L, James AP, Flicker L, Esselmann H, Wiltfang J. Plasma lipoprotein beta-amyloid in subjects with Alzheimer's disease or mild cognitive impairment. Ann Clin Biochem. 2008 Jul;45(Pt 4):395-403.
  • Maler JM, Spitzer P, Klafki HW, Esselmann H, Bibl M, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Adherence-dependent shifts in the patterns of beta-amyloid peptides secreted by human mononuclear phagocytes. Brain Behav Immun. 2008 Oct;22(7):1044-8.
  • Lewczuk P, Wiltfang J. Neurochemical dementia diagnostics: State of the art and research perspectives. Proteomics. 2008 Mar;8(6):1292-301.
    Lewczuk P, Kornhuber J, Vanderstichele H, Vanmechelen E, Esselmann H, Bibl M, Wolf S, Otto M, Reulbach U, Kolsch H, Jessen F, Schroder J, Schonknecht P, Hampel H, Peters O, Weimer E, Perneczky R, Jahn H, Luckhaus C, Lamla U, Supprian T, Maler JM, Wiltfang J. Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study. Neurobiol Aging. 2008 Jun;29(6):812-8.
  • Lewczuk P, Kamrowski-Kruck H, Peters O, Heuser I, Jessen F, Popp J, Burger K, Hampel H, Frolich L, Wolf S, Prinz B, Jahn H, Luckhaus C, Perneczky R, Hull M, Schroder J, Kessler H, Pantel J, Gertz HJ, Klafki HW, Kolsch H, Reulbach U, Esselmann H, Maler JM, Bibl M, Kornhuber J, Wiltfang J. Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study. Mol Psychiatry. 2008 Jul 29.
  • Lewczuk P, Hornegger J, Zimmermann R, Otto M, Wiltfang J, Kornhuber J. Neurochemical dementia diagnostics: assays in CSF and blood. Eur Arch Psychiatry Clin Neurosci. 2008 Nov;258 Suppl 5:44-9.
  • Kornhuber J, Tripal P, Reichel M, Terfloth L, Bleich S, Wiltfang J, Gulbins E. Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. J Med Chem. 2008 Jan 24;51(2):219-37.
  • Kolsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Kornhuber J, Frolich L, Heuser I, Peters O, Schulz JB, Schwab SG, Maier W. Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease. Neurosci Lett. 2008 Jul 25;440(1):68-71.
  • Kessler H, Pajonk FG, Bach D, Schneider-Axmann T, Falkai P, Herrmann W, Multhaup G, Wiltfang J, Schafer S, Wirths O, Bayer TA. Effect of copper intake on CSF parameters in patients with mild Alzheimer's disease: a pilot phase 2 clinical trial. J Neural Transm. 2008 Dec;115(12):1651-9.
  • Hoglund K, Hansson O, Buchhave P, Zetterberg H, Lewczuk P, Londos E, Blennow K, Minthon L, Wiltfang J. Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides. Neurodegener Dis. 2008;5(5):268-76.
  • Henkel AW, Sperling W, Rotter A, Reulbach U, Reichardt C, Bonsch D, Maler JM, Kornhuber J, Wiltfang J. Antidepressant drugs modulate growth factors in cultured cells. BMC Pharmacol. 2008;8:6.
  • Hamacher M, Stephan C, Hardt T, Eisenacher M, Henkel A, Wiltfang J, Jimenez CR, Park YM, Marcus K, Meyer HE. Applications in brain proteomics: 8(th) HUPO Brain Proteome Project Workshop 7 October 2007, Seoul, Korea. Proteomics. 2008 May;8(9):1750-3.
    Hamacher M, Eisenacher M, Tribl F, Stephan C, Marcus K, Hardt T, Wiltfang J, Martens L, Desiderio D, Gutstein H, Park YM, Meyer HE. The HUPO Brain Proteome project wish list--summary of the 9(th) HUPO BPP Workshop 9-10 January 2008, Barbados. Proteomics. 2008 Jun;8(11):2160-4.
  • Czirr E, Cottrell BA, Leuchtenberger S, Kukar T, Ladd TB, Esselmann H, Paul S, Schubenel R, Torpey JW, Pietrzik CU, Golde TE, Wiltfang J, Baumann K, Koo EH, Weggen S. Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase. J Biol Chem. 2008 Jun 20;283(25):17049-54.
  • Brechlin P, Jahn O, Steinacker P, Cepek L, Kratzin H, Lehnert S, Jesse S, Mollenhauer B, Kretzschmar HA, Wiltfang J, Otto M. Cerebrospinal fluid-optimized two-dimensional difference gel electrophoresis (2-D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease. Proteomics. 2008 Oct;8(20):4357-66.
  • Bibl M, Wiltfang J. Diagnostic and prognostic needs in neurodegenerative disorders: focus on proteomics. Expert Rev Proteomics. 2008 Apr;5(2):153-6.
  • Bibl M, Wiltfang J. [New perspectives in the laboratory diagnosis of dementia]. Nervenarzt. 2008 Nov;79 Suppl 3:139-46; quiz 47-8.
  • Bibl M, Mollenhauer B, Esselmann H, Schneider M, Lewczuk P, Welge V, Gross M, Falkai P, Kornhuber J, Wiltfang J. Cerebrospinal fluid neurochemical phenotypes in vascular dementias: original data and mini-review. Dement Geriatr Cogn Disord. 2008;25(3):256-65.


2007

  • Wiltfang J, Esselmann H, Bibl M, Hull M, Hampel H, Kessler H, Frolich L, Schroder J, Peters O, Jessen F, Luckhaus C, Perneczky R, Jahn H, Fiszer M, Maler JM, Zimmermann R, Bruckmoser R, Kornhuber J, Lewczuk P. Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load. J Neurochem. 2007 May;101(4):1053-9.
  • Weih M, Wiltfang J, Kornhuber J. Non-pharmacologic prevention of Alzheimer's disease: nutri-tional and life-style risk factors. J Neural Transm. 2007 Sep;114(9):1187-97.
  • Waltereit R, Schulte-Brochterbeck G, Wiltfang J, Frolich L. AIDS dementia complex and Ha-shimoto encephalopathy in a senescent woman. Int J Geriatr Psychiatry. 2007 Dec;22(12):1267-8.
  • Thuerauf N, Lunkenheimer J, Lunkenheimer B, Sperling W, Bleich S, Schlabeck M, Wiltfang J, Kornhuber J. Memantine fails to facilitate partial cigarette deprivation in smokers--no role of Memanti-ne in the treatment of nicotine dependency? J Neural Transm. 2007 Mar;114(3):351-7.
  • Sperling W, Kornhuber J, Wiltfang J, Bleich S. Combined VNS-rTMS treatment in a patient with therapy resistant depression. Pharmacopsychiatry. 2007 Jan;40(1):39-40.
  • Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA. Tyrosi-ne 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate. Neurodegener Dis. 2007;4(2-3):78-87.
  • Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA. Tyr687 dependent APP endocytosis and Abeta production. J Mol Neurosci. 2007;32(1):1-8.
  • Popp J, Thal DR, Lewczuk P, Wiltfang J, Jessen F. Histologically confirmed amyloid depositi-on and low CSF Abeta42 in a cognitively normal subject. J Neurol. 2007 Jul;254(7):970-1.
  • Mollenhauer B, Steinacker P, Bahn E, Bibl M, Brechlin P, Schlossmacher MG, Locascio JJ, Wiltfang J, Kretzschmar HA, Poser S, Trenkwalder C, Otto M. Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies. Neurodegener Dis. 2007;4(5):366-75.
  • Mollenhauer B, Bibl M, Esselmann H, Steinacker P, Trenkwalder C, Wiltfang J, Otto M. Tauo-pathies and synucleinopathies: Do cerebrospinal fluid beta-amyloid peptides reflect disease-specific pathogenesis? J Neural Transm. 2007 Jul;114(7):919-27.
  • Maler JM, Klafki HW, Paul S, Spitzer P, Groemer TW, Henkel AW, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: evidence for novel Abeta species. Proteomics. 2007 Oct;7(20):3815-20.
  • Maihofner C, Sperling W, Kaltenhauser M, Bleich S, de Zwaan M, Wiltfang J, Thurauf N, Elst-ner S, Reulbach U, Lewczuk P, Kornhuber J, Ropohl A. Spontaneous magnetoencephalographic acti-vity in patients with obsessive-compulsive disorder. Brain Res. 2007 Jan 19;1129(1):200-5.
  • Lehrl S, Gerstmeyer K, Jacob JH, Frieling H, Henkel AW, Meyrer R, Wiltfang J, Kornhuber J, Bleich S. Blue light improves cognitive performance. J Neural Transm. 2007;114(4):457-60.
  • Kornhuber J, Kennepohl EM, Bleich S, Wiltfang J, Kraus T, Reulbach U, Meineke I. Memanti-ne pharmacotherapy: a naturalistic study using a population pharmacokinetic approach. Clin Pharma-cokinet. 2007;46(7):599-612.
  • Henkel AW, Dittrich PS, Groemer TW, Lemke EA, Klingauf J, Klafki HW, Lewczuk P, Essel-mann H, Schwille P, Kornhuber J, Wiltfang J. Immune complexes of auto-antibodies against A beta 1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients. Mol Psychiatry. 2007 Jun;12(6):601-10.
  • Hamacher M, Stephan C, Eisenacher M, Lewczuk P, Wiltfang J, Martens L, Vizcaino JA, Kwon KH, Yoo JS, Park YM, Beckers J, Horsch M, de Angelis MH, Cho ZH, Apweiler R, Meyer HE. High Performance Proteomics: 7th HUPO Brain Proteome Project Workshop March 7-9, 2007 Well-come Trust Conference Centre, Hinxton, UK. Proteomics. 2007 Aug;7(15):2490-6.
  • Englund H, Anneren G, Gustafsson J, Wester U, Wiltfang J, Lannfelt L, Blennow K, Hoglund K. Increase in beta-amyloid levels in cerebrospinal fluid of children with Down syndrome. Dement Ge-riatr Cogn Disord. 2007;24(5):369-74.
  • Cepek L, Brechlin P, Steinacker P, Mollenhauer B, Klingebiel E, Bibl M, Kretzschmar HA, Wilt-fang J, Otto M. Proteomic analysis of the cerebrospinal fluid of patients with Creutzfeldt-Jakob disea-se. Dement Geriatr Cogn Disord. 2007;23(1):22-8.
  • Bibl M, Mollenhauer B, Wolf S, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. Reduced CSF carboxyterminally truncated Abeta peptides in frontotemporal lobe degenerations. J Neural Transm. 2007;114(5):621-8.
  • Bibl M, Mollenhauer B, Lewczuk P, Esselmann H, Wolf S, Trenkwalder C, Otto M, Stiens G, Ruther E, Kornhuber J, Wiltfang J. Validation of amyloid-beta peptides in CSF diagnosis of neurode-generative dementias. Mol Psychiatry. 2007 Jul;12(7):671-80.
  • Bibl M, Esselmann H, Mollenhauer B, Wiltfang J. Aminoterminally truncated and oxidized amy-loid-beta peptide species in Alzheimer's disease. Neuroscience. 2007 Apr 25;146(1):17-8.
  • Bibl M, Esselmann H, Mollenhauer B, Weniger G, Welge V, Liess M, Lewczuk P, Otto M, Schulz JB, Trenkwalder C, Kornhuber J, Wiltfang J. Blood-based neurochemical diagnosis of vascular dementia: a pilot study. J Neurochem. 2007 Oct;103(2):467-74.


2006

  • Mollenhauer B, Trenkwalder C, von Ahsen N, Bibl M, Steinacker P, Brechlin P, Schindehuette J, Poser S, Wiltfang J, Otto M. Beta-amlyoid 1-42 and tau-protein in cerebrospinal fluid of patients with Parkinson's disease dementia. Dement Geriatr Cogn Disord. 2006;22(3):200-8.
  • Mollenhauer B, Bibl M, Wiltfang J, Steinacker P, Ciesielczyk B, Neubert K, Trenkwalder C, Otto M. Total tau protein, phosphorylated tau (181p) protein, beta-amyloid(1-42), and beta-amyloid(1-40) in cerebrospinal fluid of patients with dementia with Lewy bodies. Clin Chem Lab Med. 2006;44(2):192-5.
  • Mollenhauer B, Bibl M, Esselmann H, Steinacker P, Trenkwalder C, Brechlin P, Wiltfang J, Otto M. Selective reduction of amyloid beta42 discriminates Alzheimer's disease from Huntington's disease: indication for distinct pathological events in amyloid beta peptide aggregation. J Neurol Neu-rosurg Psychiatry. 2006 Oct;77(10):1201-3.
  • Maler JM, Spitzer P, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Decreased circulating CD34+ stem cells in early Alzheimer's disease: Evidence for a deficient hematopoietic brain support? Mol Psychiatry. 2006 Dec;11(12):1113-5.
  • Lewczuk P, Kornhuber J, Wiltfang J. The German Competence Net Dementias: standard ope-rating procedures for the neurochemical dementia diagnostics. J Neural Transm. 2006 Aug;113(8):1075-80.
  • Lewczuk P, Beck G, Ganslandt O, Esselmann H, Deisenhammer F, Regeniter A, Petereit HF, Tumani H, Gerritzen A, Oschmann P, Schroder J, Schonknecht P, Zimmermann K, Hampel H, Burger K, Otto M, Haustein S, Herzog K, Dannenberg R, Wurster U, Bibl M, Maler JM, Reubach U, Kornhuber J, Wiltfang J. International quality control survey of neurochemical dementia diagnostics. Neurosci Lett. 2006 Nov 27;409(1):1-4.
  • Lewczuk P, Beck G, Esselmann H, Bruckmoser R, Zimmermann R, Fiszer M, Bibl M, Maler JM, Kornhuber J, Wiltfang J. Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid beta peptides. Clin Chem. 2006 Feb;52(2):332-4.
  • Kornhuber J, Wiltfang J, Riederer P, Bleich S. Neuroleptic drugs in the human brain: clinical impact of persistence and region-specific distribution. Eur Arch Psychiatry Clin Neurosci. 2006 Aug;256(5):274-80.
  • Kornhuber J, Weigmann H, Rohrich J, Wiltfang J, Bleich S, Meineke I, Zochling R, Hartter S, Riederer P, Hiemke C. Region specific distribution of levomepromazine in the human brain. J Neural Transm. 2006 Mar;113(3):387-97.
  • Kornhuber J, Riederer P, Bleich S, Wiltfang J, Kraus T, Meineke I. Pharmacokinetic characte-rization of amantadine in human brain tissue. Ther Drug Monit. 2006 Oct;28(5):693-5.
  • Klafki HW, Staufenbiel M, Kornhuber J, Wiltfang J. Therapeutic approaches to Alzheimer's disease. Brain. 2006 Nov;129(Pt 11):2840-55.
  • Hillemacher T, Bleich S, Wiltfang J, Weber M, Kornhuber J, Frieling H. Should aspirin be dis-continued for diagnostic lumbar puncture? J Am Geriatr Soc. 2006 Jan;54(1):181-2.
  • Henkel AW, Upmann I, Bartl CR, Bonsch D, Reichardt C, Maler JM, Nurnberger M, Umstatter R, Reulbach U, Kornhuber J, Wiltfang J. Light-induced exocytosis in cell development and differentia-tion. J Cell Biochem. 2006 Apr 15;97(6):1393-406.
  • Hamacher M, Apweiler R, Arnold G, Becker A, Bluggel M, Carrette O, Colvis C, Dunn MJ, Frohlich T, Fountoulakis M, van Hall A, Herberg F, Ji J, Kretzschmar H, Lewczuk P, Lubec G, Marcus K, Martens L, Palacios Bustamante N, Park YM, Pennington SR, Robben J, Stuhler K, Reidegeld KA, Riederer P, Rossier J, Sanchez JC, Schrader M, Stephan C, Tagle D, Thiele H, Wang J, Wiltfang J, Yoo JS, Zhang C, Klose J, Meyer HE. HUPO Brain Proteome Project: summary of the pilot phase and introduction of a comprehensive data reprocessing strategy. Proteomics. 2006 Sep;6(18):4890-8.
  • Buerger K, Otto M, Teipel SJ, Zinkowski R, Blennow K, DeBernardis J, Kerkman D, Schroder J, Schonknecht P, Cepek L, McCulloch C, Moller HJ, Wiltfang J, Kretzschmar H, Hampel H. Dissocia-tion between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob di-sease. Neurobiol Aging. 2006 Jan;27(1):10-5.
  • Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Trenkwalder C, Brechlin P, Ruther E, Korn-huber J, Otto M, Wiltfang J. CSF diagnosis of Alzheimer's disease and dementia with Lewy bodies. J Neural Transm. 2006 Nov;113(11):1771-8.
  • Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Klafki HW, Sparbier K, Smirnov A, Cepek L, Trenkwalder C, Ruther E, Kornhuber J, Otto M, Wiltfang J. CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia. Brain. 2006 May;129(Pt 5):1177-87.
  • Bentahir M, Nyabi O, Verhamme J, Tolia A, Horre K, Wiltfang J, Esselmann H, De Strooper B. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms. J Neuro-chem. 2006 Feb;96(3):732-42.

2005

  • Wiltfang J, Lewczuk P, Riederer P, Grunblatt E, Hock C, Scheltens P, Hampel H, Vandersti-chele H, Iqbal K, Galasko D, Lannfelt L, Otto M, Esselmann H, Henkel AW, Kornhuber J, Blennow K. Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia. World J Biol Psychiatry. 2005;6(2):69-84.
  • Steinacker P, Schwarz P, Reim K, Brechlin P, Jahn O, Kratzin H, Aitken A, Wiltfang J, Aguzzi A, Bahn E, Baxter HC, Brose N, Otto M. Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein. Mol Cell Biol. 2005 Feb;25(4):1339-46.
  • Mollenhauer B, Cepek L, Bibl M, Wiltfang J, Schulz-Schaeffer WJ, Ciesielczyk B, Neumann M, Steinacker P, Kretzschmar HA, Poser S, Trenkwalder C, Otto M. Tau protein, Abeta42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies. Dement Geriatr Cogn Disord. 2005;19(2-3):164-70.
  • Mollenhauer B, Bibl M, Trenkwalder C, Stiens G, Cepek L, Steinacker P, Ciesielczyk B, Neu-bert K, Wiltfang J, Kretzschmar HA, Poser S, Otto M. Follow-up investigations in cerebrospinal fluid of patients with dementia with Lewy bodies and Alzheimer's disease. J Neural Transm. 2005 Jul;112(7):933-48.
  • Maler JM, Esselmann H, Wiltfang J, Kunz N, Lewczuk P, Reulbach U, Bleich S, Ruther E, Kornhuber J. Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons. Brain Res. 2005 Aug 9;1052(2):156-62.
  • Lotz M, Ebert S, Esselmann H, Iliev AI, Prinz M, Wiazewicz N, Wiltfang J, Gerber J, Nau R. Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures. J Neurochem. 2005 Jul;94(2):289-98.
  • Kornhuber J, Medlin A, Bleich S, Jendrossek V, Henkel AW, Wiltfang J, Gulbins E. High activi-ty of acid sphingomyelinase in major depression. J Neural Transm. 2005 Nov;112(11):1583-90.
  • Hoglund K, Syversen S, Lewczuk P, Wallin A, Wiltfang J, Blennow K. Statin treatment and a disease-specific pattern of beta-amyloid peptides in Alzheimer's disease. Exp Brain Res. 2005 Jul;164(2):205-14.
  • Cepek L, Steinacker P, Mollenhauer B, Wiese B, Ciesielczyk B, Bibl M, Wiltfang J, Zerr I, Schulz-Schaeffer W, Kretzschmar HA, Poser S, Otto M. Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Dement Geriatr Cogn Disord. 2005;19(5-6):376-82.
  • Bleich S, Otto M, Zerr I, Kropp S, Kretzschmar HA, Wiltfang J. Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid. Gerontology. 2005 Mar-Apr;51(2):142-4.
  • Bahn E, Wiltfang J, Nolte W, Ramadori G, Steinhoff B, Ruther E, Kurth C. Quantification of changes in electroencephalographic power spectra in a patient with Budd-Chiari-syndrome after im-plantation of a transjugular intrahepatic portosystemic stent shunt (TIPSS). Metab Brain Dis. 2005 Mar;20(1):1-6.


2004

  • Wiltfang J, Lewczuk P, Maler M, Bleich S, Smirnov A, Kornhuber J. [Neurochemical early and differential diagnostics for Alzheimer's disease]. MMW Fortschr Med. 2004 Sep 16;146(38):38-40.
  • Steinacker P, Mollenhauer B, Bibl M, Cepek L, Esselmann H, Brechlin P, Lewczuk P, Poser S, Kretzschmar HA, Wiltfang J, Trenkwalder C, Otto M. Heart fatty acid binding protein as a potential diagnostic marker for neurodegenerative diseases. Neurosci Lett. 2004 Nov 3;370(1):36-9.
  • Otto M, Cepek L, Ratzka P, Doehlinger S, Boekhoff I, Wiltfang J, Irle E, Pergande G, Ellers-Lenz B, Windl O, Kretzschmar HA, Poser S, Prange H. Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study. Neurology. 2004 Mar 9;62(5):714-8.
  • Lewczuk P, Esselmann H, Otto M, Maler JM, Henkel AW, Henkel MK, Eikenberg O, Antz C, Krause WR, Reulbach U, Kornhuber J, Wiltfang J. Neurochemical diagnosis of Alzheimer's dementia by CSF Abeta42, Abeta42/Abeta40 ratio and total tau. Neurobiol Aging. 2004 Mar;25(3):273-81.
  • Lewczuk P, Esselmann H, Groemer TW, Bibl M, Maler JM, Steinacker P, Otto M, Kornhuber J, Wiltfang J. Amyloid beta peptides in cerebrospinal fluid as profiled with surface enhanced laser de-sorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's di-sease. Biol Psychiatry. 2004 Mar 1;55(5):524-30.
  • Lewczuk P, Esselmann H, Bibl M, Paul S, Svitek J, Miertschischk J, Meyrer R, Smirnov A, Maler JM, Klein C, Otto M, Bleich S, Sperling W, Kornhuber J, Ruther E, Wiltfang J. Electrophoretic separation of amyloid beta peptides in plasma. Electrophoresis. 2004 Oct;25(20):3336-43.
  • Lewczuk P, Esselmann H, Bibl M, Beck G, Maler JM, Otto M, Kornhuber J, Wiltfang J. Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer's disease: original data and review of the literature. J Mol Neurosci. 2004;23(1-2):115-22.
  • Kornhuber J, Wiltfang J, Bleich S. The etiopathogenesis of schizophrenias. Pharmacopsychi-atry. 2004 Nov;37 Suppl 2:S103-12.
  • Hampel H, Teipel SJ, Fuchsberger T, Andreasen N, Wiltfang J, Otto M, Shen Y, Dodel R, Du Y, Farlow M, Moller HJ, Blennow K, Buerger K. Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment. Mol Psychiatry. 2004 Jul;9(7):705-10.
  • Esselmann H, Maler JM, Kunz N, Otto M, Paul S, Lewczuk P, Ruther E, Kornhuber J, Wiltfang J. Lithium decreases secretion of Abeta1-42 and C-truncated species Abeta1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta1-38. Neurodegener Dis. 2004;1(4-5):236-41.
  • Bibl M, Esselmann H, Otto M, Lewczuk P, Cepek L, Ruther E, Kornhuber J, Wiltfang J. Ce-rebrospinal fluid amyloid beta peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: indication of carrier-mediated epitope masking of amyloid beta peptides. Electrophoresis. 2004 Sep;25(17):2912-8.


2003

  • Wiltfang J, Esselmann H, Smirnov A, Bibl M, Cepek L, Steinacker P, Mollenhauer B, Buerger K, Hampel H, Paul S, Neumann M, Maler M, Zerr I, Kornhuber J, Kretzschmar HA, Poser S, Otto M. Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Ann Neurol. 2003 Aug;54(2):263-7.
  • Riemenschneider M, Wagenpfeil S, Vanderstichele H, Otto M, Wiltfang J, Kretzschmar H, Vanmechelen E, Forstl H, Kurz A. Phospho-tau/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt-Jakob disease from other dementias. Mol Psychiatry. 2003 Mar;8(3):343-7.
  • Ratzka P, Dohlinger S, Cepek L, Steinacker P, Arlt S, Jacobi C, Schroter A, Wiltfang J, Prange H, Kretzschmar HA, Poser S, Otto M. Different binding pattern of antibodies to prion protein on lymphocytes from patients with sporadic Creutzfeldt-Jakob disease. Neurosci Lett. 2003 May 29;343(1):29-32.
  • Otto M, Wiltfang J. Differential diagnosis of neurodegenerative diseases with special emphasis on Creutzfeldt-Jakob disease. Restor Neurol Neurosci. 2003;21(3-4):191-209.
  • Maler JM, Seifert W, Huther G, Wiltfang J, Ruther E, Kornhuber J, Bleich S. Homocysteine induces cell death of rat astrocytes in vitro. Neurosci Lett. 2003 Aug 21;347(2):85-8.
  • Lewczuk P, Esselmann H, Meyer M, Wollscheid V, Neumann M, Otto M, Maler JM, Ruther E, Kornhuber J, Wiltfang J. The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide. Rapid Commun Mass Spectrom. 2003;17(12):1291-6.
  • Grasel E, Wiltfang J, Kornhuber J. Non-drug therapies for dementia: an overview of the cur-rent situation with regard to proof of effectiveness. Dement Geriatr Cogn Disord. 2003;15(3):115-25.
  • Diehl J, Staehelin H, Wiltfang J, Hampel H, Calabrese P, Monsch A, Schmid R, Romero B, Schunk M, Kuhlmann HP, Wolter-Henseler DK, Mauerer C, Stoppe G, Kurz A. [German-speaking memory clinics: state of the art and practical recommendations]. Z Gerontol Geriatr. 2003 Jun;36(3):189-96.
  • Bleich S, Wiltfang J, Kornhuber J. Memantine in moderate-to-severe Alzheimer's disease. N Engl J Med. 2003 Aug 7;349(6):609-10; author reply -10.
  • Bleich S, Sperling W, Wiltfang J, Maler JM, Kornhuber J. [Excitatory neurotransmission in alcoholism]. Fortschr Neurol Psychiatr. 2003 Jul;71 Suppl 1:S36-44.
  • Bleich S, Romer K, Wiltfang J, Kornhuber J. Glutamate and the glutamate receptor system: a target for drug action. Int J Geriatr Psychiatry. 2003 Sep;18(Suppl 1):S33-40. 


2002

  • Wiltfang J, Esselmann H, Bibl M, Smirnov A, Otto M, Paul S, Schmidt B, Klafki HW, Maler M, Dyrks T, Bienert M, Beyermann M, Ruther E, Kornhuber J. Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J Neurochem. 2002 May;81(3):481-96.
  • Sommer M, Dieterich A, Ruther E, Paulus W, Wiltfang J. Increased transcranial magnetic mo-tor threshold after ECT. A case report. Eur Arch Psychiatry Clin Neurosci. 2002 Oct;252(5):250-2.
  • Scheschonka A, Bleich S, Buchwald AB, Ruther E, Wiltfang J. Development of obsessive-compulsive behaviour following cortisone treatment. Pharmacopsychiatry. 2002 Mar;35(2):72-4.
  • Otto M, Wiltfang J, Cepek L, Neumann M, Mollenhauer B, Steinacker P, Ciesielczyk B, Schulz-Schaeffer W, Kretzschmar HA, Poser S. Tau protein and 14-3-3 protein in the differential dia-gnosis of Creutzfeldt-Jakob disease. Neurology. 2002 Jan 22;58(2):192-7.
  • Jordan W, Hagedohm J, Wiltfang J, Laier-Groeneveld G, Tumani H, Rodenbeck A, Ruther E, Hajak G. Biochemical markers of cerebrovascular injury in sleep apnoea syndrome. Eur Respir J. 2002 Jul;20(1):158-64.
  • Baxter HC, Fraser JR, Liu WG, Forster JL, Clokie S, Steinacker P, Otto M, Bahn E, Wiltfang J, Aitken A. Specific 14-3-3 isoform detection and immunolocalization in prion diseases. Biochem Soc Trans. 2002 Aug;30(4):387-91.
  • Bahn E, Nolte W, Kurth C, Ramadori G, Ruther E, Wiltfang J. Quantification of the electroen-cephalographic theta/alpha ratio for the assessment of portal-systemic encephalopathy following im-plantation of transjugular intrahepatic portosystemic stent shunt (TIPSS). Metab Brain Dis. 2002 Mar;17(1):19-28.


2001

  • Wiltfang J, Schenk-Dapra B, Stiens G, Bleich S, Bandelow B, Muller P, Niedmann PD, Arm-strong VW, Ruther E. Clozapine-associated elevation of plasma cholinesterase. Eur Arch Psychiatry Clin Neurosci. 2001 Dec;251(6):269-71.
  • Wiltfang J, Esselmann H, Maler JM, Bleich S, Huther G, Kornhuber J. Molecular biology of Alzheimer's dementia and its clinical relevance to early diagnosis and new therapeutic strategies. Ge-rontology. 2001 Mar-Apr;47(2):65-71.
  • Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Ruther E, Kornhuber J, Annaert W, De Strooper B, Saftig P. Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells. J Biol Chem. 2001 Nov 16;276(46):42645-57.
  • Tschampa HJ, Schulz-Schaeffer W, Wiltfang J, Poser S, Otto M, Neumann M, Kretzschmar HA. Decreased CSF amyloid beta42 and normal tau levels in dementia with Lewy bodies. Neurology. 2001 Feb 27;56(4):576.
  • Sommer M, Dieterich A, Krause C, Ruther E, Wiltfang J. Subclinical pancreatitis related to mirtazapine - a case report. Pharmacopsychiatry. 2001 Jul;34(4):158-9.
  • Ratzka P, Schroter A, Cepek L, Henkel K, Wiltfang J, Kretzschmar HA, Prange H, Poser S, Otto M. Unaltered apoptotic behaviour of mononuclear cells from patients with sporadic Creutzfeldt-Jakob disease. J Neurol. 2001 Aug;248(8):690-4.
  • Itoh N, Arai H, Urakami K, Ishiguro K, Ohno H, Hampel H, Buerger K, Wiltfang J, Otto M, Kretzschmar H, Moeller HJ, Imagawa M, Kohno H, Nakashima K, Kuzuhara S, Sasaki H, Imahori K. Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease. Ann Neurol. 2001 Aug;50(2):150-6.
  • Bleich S, Bleich K, Wiltfang J, Maler JM, Kornhuber J. [Glutamatergic neurotransmission in schizophrenics]. Fortschr Neurol Psychiatr. 2001 Sep;69 Suppl 2:S56-61.


2000

  • Smirnov AV, Tumani H, Henne S, Barchfeld S, Olgemoller U, Wiltfang J, Lange P, Mader M, Nau R. Glutamine synthetase in experimental meningitis: increased ratio of the subunits 3 and 2 may indicate enhanced activity. Clin Chim Acta. 2000 Feb 25;292(1-2):1-12.
  • Ruther E, Glaser A, Bleich S, Degner D, Wiltfang J. A prospective PMS study to validate the sensitivity for change of the D-scale in advanced stages of dementia using the NMDA-antagonist me-mantine. Pharmacopsychiatry. 2000 May;33(3):103-8.
  • Otto M, Holthusen S, Bahn E, Sohnchen N, Wiltfang J, Geese R, Fischer A, Reimers CD. Bo-xing and running lead to a rise in serum levels of S-100B protein. Int J Sports Med. 2000 Nov;21(8):551-5.
  • Otto M, Esselmann H, Schulz-Shaeffer W, Neumann M, Schroter A, Ratzka P, Cepek L, Zerr I, Steinacker P, Windl O, Kornhuber J, Kretzschmar HA, Poser S, Wiltfang J. Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Neurology. 2000 Mar 14;54(5):1099-102.
  • Nolte W, Ehrenreich H, Wiltfang J, Pahl K, Unterberg K, Kamrowski-Kruck H, Schindler CG, Figulla HR, Buchwald AB, Hartmann H, Ramadori G. Systemic and splanchnic endothelin-1 plasma levels in liver cirrhosis before and after transjugular intrahepatic portosystemic shunt (TIPS). Liver. 2000 Feb;20(1):60-5.
  • Kropp S, Schlimme J, Bleich S, Wiltfang J, Dietrich DE, Emrich HM. [Diagnostic steps in Alz-heimer dementia before treatment with new antidimentives]. Fortschr Neurol Psychiatr. 2000 Jun;68(6):257-61.
  • Bleich S, Spilker K, Kurth C, Degner D, Quintela-Schneider M, Javaheripour K, Ruther E, Kornhuber J, Wiltfang J. Oxidative stress and an altered methionine metabolism in alcoholism. Neu-rosci Lett. 2000 Nov 3;293(3):171-4.
  • Bleich S, Kropp S, Degner D, Zerr I, Pilz J, Gleiter CH, Otto M, Ruther E, Kretzschmar HA, Wiltfang J, Kornhuber J, Poser S. Creutzfeldt-Jakob disease and oxidative stress. Acta Neurol Scand. 2000 May;101(5):332-4.
  • Bleich S, Degner D, Wiltfang J, Maler JM, Niedmann P, Cohrs S, Mangholz A, Porzig J, Sprung R, Ruther E, Kornhuber J. Elevated homocysteine levels in alcohol withdrawal. Alcohol Alco-hol. 2000 Jul-Aug;35(4):351-4.


1999

  • Wiltfang J, Otto M, Baxter HC, Bodemer M, Steinacker P, Bahn E, Zerr I, Kornhuber J, Kretzschmar HA, Poser S, Ruther E, Aitken A. Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. J Neurochem. 1999 Dec;73(6):2485-90.
  • Wiltfang J, Nolte W, von Heppe J, Bahn E, Pilz J, Hajak G, Ruther E, Ramadori G. Sleep di-sorders and portal-systemic encephalopathy following transjugular intrahepatic portosystemic stent shunt in patients with liver cirrhosis. Relation to plasma tryptophan. Adv Exp Med Biol. 1999;467:169-76.
  • Wiltfang J, Nolte W, Otto M, Wildberg J, Bahn E, Figulla HR, Pralle L, Hartmann H, Ruther E, Ramadori G. Elevated serum levels of astroglial S100beta in patients with liver cirrhosis indicate early and subclinical portal-systemic encephalopathy. Metab Brain Dis. 1999 Dec;14(4):239-51.
  • Tumani H, Otto M, Gefeller O, Wiltfang J, Herrendorf G, Mogge S, Steinhoff BJ. Kinetics of serum neuron-specific enolase and prolactin in patients after single epileptic seizures. Epilepsia. 1999 Jun;40(6):713-8.
  • Steinhoff BJ, Tumani H, Otto M, Mursch K, Wiltfang J, Herrendorf G, Bittermann HJ, Felgen-hauer K, Paulus W, Markakis E. Cisternal S100 protein and neuron-specific enolase are elevated and site-specific markers in intractable temporal lobe epilepsy. Epilepsy Res. 1999 Aug;36(1):75-82.
  • Otto M, Wiltfang J, Poser S, Kornhuber J. [Comments on the article by K.Buch et al. Tau pro-tein: a potential biological marker for early detection of Alzheimer disease. Nervenarzt (1998) 69:379-385]. Nervenarzt. 1999 Jul;70(7):668-70.
  • Lewczuk P, Wiltfang J, Lange M, Jahn H, Reiber H, Ehrenreich H. Prothrombin concentration in the cerebrospinal fluid is not altered in Alzheimer's disease. Neurochem Res. 1999 Dec;24(12):1531-4.
  • Kornhuber J, Schultz A, Wiltfang J, Meineke I, Gleiter CH, Zochling R, Boissl KW, Leblhuber F, Riederer P. Persistence of haloperidol in human brain tissue. Am J Psychiatry. 1999 Jun;156(6):885-90.
  • Kornhuber J, Maler M, Wiltfang J, Bleich S, Degner D, Ruther E. [Neuronal potassium channel opening with flupirtine]. Fortschr Neurol Psychiatr. 1999 Oct;67(10):466-75.
  • Kornhuber J, Jellinger K, Wiltfang J, Leblhuber F, Riederer P. The N-methyl-D-aspartate re-ceptor channel blocker amantadine does not cause histopathological alterations in human brain tissue. Acta Neuropathol. 1999 Jul;98(1):85-90.
  • Kornhuber J, Bleich S, Wiltfang J, Maler M, Parsons CG. Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium chan-nels. Rapid communication. J Neural Transm. 1999;106(9-10):857-67.
  • Hulstaert F, Blennow K, Ivanoiu A, Schoonderwaldt HC, Riemenschneider M, De Deyn PP, Bancher C, Cras P, Wiltfang J, Mehta PD, Iqbal K, Pottel H, Vanmechelen E, Vanderstichele H. Im-proved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF. Neurology. 1999 May 12;52(8):1555-62.
  • Beekes M, Otto M, Wiltfang J, Bahn E, Poser S, Baier M. Late increase of serum S100 beta protein levels in hamsters after oral or intraperitoneal infection with scrapie. J Infect Dis. 1999 Aug;180(2):518-20.


1998

  • Zerr I, Bodemer M, Gefeller O, Otto M, Poser S, Wiltfang J, Windl O, Kretzschmar HA, Weber T. Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease. Ann Neurol. 1998 Jan;43(1):32-40.
  • Wiltfang J, Nolte W, Weissenborn K, Kornhuber J, Ruther E. Psychiatric aspects of portal-systemic encephalopathy. Metab Brain Dis. 1998 Dec;13(4):379-89.
  • Otto M, Wiltfang J, Schutz E, Zerr I, Otto A, Pfahlberg A, Gefeller O, Uhr M, Giese A, Weber T, Kretzschmar HA, Poser S. Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study. BMJ. 1998 Feb 21;316(7131):577-82.
  • Otto M, Beekes M, Wiltfang J, Bahn E, Poser S, Diringer H. Elevated levels of serum S100 beta protein in scrapie hamsters. J Neurovirol. 1998 Oct;4(5):572-3.
  • Otto M, Bahn E, Wiltfang J, Boekhoff I, Beuche W. Decrease of S100 beta protein in serum of patients with amyotrophic lateral sclerosis. Neurosci Lett. 1998 Jan 16;240(3):171-3.
  • Nolte W, Wiltfang J, Schindler CG, Unterberg K, Finkenstaedt M, Niedmann PD, Hartmann H, Ramadori G. Bright basal ganglia in T1-weighted magnetic resonance images are frequent in patients with portal vein thrombosis without liver cirrhosis and not suggestive of hepatic encephalopathy. J Hepatol. 1998 Sep;29(3):443-9.
  • Nolte W, Wiltfang J, Schindler C, Munke H, Unterberg K, Zumhasch U, Figulla HR, Werner G, Hartmann H, Ramadori G. Portosystemic hepatic encephalopathy after transjugular intrahepatic porto-systemic shunt in patients with cirrhosis: clinical, laboratory, psychometric, and electroencepha-lographic investigations. Hepatology. 1998 Nov;28(5):1215-25.
  • Kornhuber J, Wiltfang J. The role of glutamate in dementia. J Neural Transm Suppl. 1998;53:277-87.


1997

  • Wiltfang J, Smirnov A, Schnierstein B, Kelemen G, Matthies U, Klafki HW, Staufenbiel M, Huther G, Ruther E, Kornhuber J. Improved electrophoretic separation and immunoblotting of beta-amyloid (A beta) peptides 1-40, 1-42, and 1-43. Electrophoresis. 1997 Mar-Apr;18(3-4):527-32.
  • Otto M, Wiltfang J, Tumani H, Zerr I, Lantsch M, Kornhuber J, Weber T, Kretzschmar HA, Poser S. Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disea-se. Neurosci Lett. 1997 Apr 11;225(3):210-2.
  • Nolte W, Figulla HR, Ringe B, Wiltfang J, Munke H, Hartmann H, Ramadori G. [TIPSS in the Budd-Chiari syndrome with portal vein thrombosis]. Dtsch Med Wochenschr. 1997 Jan 31;122(5):116-21.
  • Nolte W, Figulla HR, Ringe B, Wiltfang J, Munke H, Hartmann H, Pausch J, Ramadori G. [Refractory hydrothorax in primary biliary cirrhosis: successful treatment with transjugular intrahepatic portosystemic stent shunt]. Dtsch Med Wochenschr. 1997 Oct 17;122(42):1275-80.
  • Huether G, Zhou D, Schmidt S, Wiltfang J, Ruther E. Long-term food restriction down-regulates the density of serotonin transporters in the rat frontal cortex. Biol Psychiatry. 1997 Jun 15;41(12):1174-80.


1996

  • Zhou D, Huether G, Wiltfang J, Hajak G, Ruther E. Serotonin transporters in the rat frontal cortex: lack of circadian rhythmicity but down-regulation by food restriction. J Neurochem. 1996 Aug;67(2):656-61.
  • Wiltfang J, Merten HA, Engelke W, Cohrs S, Hajak G, Ruther E. [Functional palatoraphy and modified chin osteotomy in surgical therapy of sleep-related respiratory disorders with obstruction of the upper airways]. Wien Med Wochenschr. 1996;146(13-14):363-5.
  • Michel U, Schneider O, Kirchhof C, Meisel S, Smirnov A, Wiltfang J, Rieckmann P. Production of follistatin in porcine endothelial cells: differential regulation by bacterial compounds and the synthe-tic glucocorticoid RU 28362. Endocrinology. 1996 Nov;137(11):4925-34.
  • Klafki HW, Wiltfang J, Staufenbiel M. Electrophoretic separation of betaA4 peptides (1-40) and (1-42). Anal Biochem. 1996 May 15;237(1):24-9.
  • Cohrs S, Herrendorf G, Wiltfang J, Rodenbeck A, Kinkelbur J, Adler L, Hajak G. [Functional palatoraphy and modified genioplasty in obstructive sleep apnea]. Wien Med Wochenschr. 1996;146(13-14):366-8.


1995

  • Nolte W, Wiltfang JG, Kunert HJ, Thiel A, Geese K, Peters K, Figulla HR, Hartmann H, Rama-dori G. [Initial clinical experiences with TIPS (transjugular intrahepatic portasystemic stent-shunt)]. Leber Magen Darm. 1995 Dec;25(6):264-6, 9-70.


1994

  • Thiel A, Wiltfang J, Lehmann K. [Problems in the perception of sexual self-determination: a neglected problem in manic patients?]. Psychiatr Prax. 1994 Jan;21(1):37-8.


1993

  • Rieckmann P, Nunke K, Burchhardt M, Albrecht M, Wiltfang J, Ulrich M, Felgenhauer K. So-luble intercellular adhesion molecule-1 in cerebrospinal fluid: an indicator for the inflammatory impair-ment of the blood-cerebrospinal fluid barrier. J Neuroimmunol. 1993 Sep;47(2):133-40.


1991

  • Wiltfang J, Arold N, Neuhoff V. A new multiphasic buffer system for sodium dodecyl sulfate-polyacrylamide gel electrophoresis of proteins and peptides with molecular masses 100,000-1000, and their detection with picomolar sensitivity. Electrophoresis. 1991 May;12(5):352-66.


1990

  • Weissenborn K, Scholz M, Hinrichs H, Wiltfang J, Schmidt FW, Kunkel H. Neurophysiological assessment of early hepatic encephalopathy. Electroencephalogr Clin Neurophysiol. 1990 Apr;75(4):289-95. 


1989

  • Kratzin HD, Wiltfang J, Karas M, Neuhoff V, Hilschmann N. Gas-phase sequencing after e-lectroblotting on polyvinylidene difluoride membranes assigns correct molecular weights to myoglobin molecular weight markers. Anal Biochem. 1989 Nov 15;183(1):1-8.