Subproject A1
Curriculum vitae |
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Zhenghong Yuan, M.D., Ph.D |
Date of birth: |
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Place of birth: |
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Work address: |
Key Laboratory of Medical Molecular Virology |
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Fudan University |
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138 Yi-Xue-Yuan Road |
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Shanghai 200032/P.R. China |
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Phone: +86 21 64161928 |
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E-Mail: yzhlab1115@sina.com |
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Academic education and qualifications: |
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Shanghai Medical University |
(Ph.D. 1990-1993 Molecular Virology) |
Nantong Medical College |
(MSc 1985-1988 Microbiology) |
Nantong Medical College |
(M.D. 1980-1985 Clinical Medicine) |
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Marie Curie Postdoctoral Research Fellow 1995-1996 |
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Professional appointments: |
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1988-1990 |
Lecturer, Department of Microbiology and Immunology, Nantong Medical College |
| 1993-1994 | Associate Professor, Department of Molecular Virology, Shanghai Medical University |
| 1997-present | Professor, Department of Molecular Virology, Shanghai Medical University |
| 1998-2001 | Deputy Vice-chairman, Department of Molecular Virology, Shanghai Medical University |
| 1999 | Visiting Scientist, Dept. of Molecular Microbiology, |
| 2002 | Visiting Professor, Lab of Virology and Infectious Diseases, Rockefeller University |
| 2002-present | Director and Professor, Key Lab of Medical Molecular Virology, Ministry of Education and Health, Shanghai Medical College, Fudan University |
2001-present |
Chairman, Standing Committee of Shanghai Virology Society, Chinese Medical Association |
2001-present |
Vice-dean, Shanghai Medical College, Fudan University |
2001-present |
Member of Chinese Society for Microbiology |
2004-present |
Vice President of Shanghai Public Health Center |
Awards and honours:
1994 Ministry of Health Science and Technology Prize
1995 European Community Marie Curie Fellowship
1997 National Natural Science Prize (3rd)
1997 China Scholarship for Research Abroad
1999 Shanghai Municipal Government Science and Technology Prize
1999 Shanghai Municipal Government Young Scientist Research Award
2000 Ministry of Education Excellent Young Teacher Research Award
2001 Ministry of Education Science and Technology Prize
2002 HYD Research Award for Young Scientist
2003 Young Investigator Award, Shanghai Bureau of Health
2004 Science and Technology First Prize, Chinese Medical Association
2004 Science and Technology Third Prize
2005 Science and Technology Third Prize
2005 Shanghai Municipal Government Science and Technology Third Prize
Publications (10 most important publications of the last 5 years, *corresponding author)
1. Yu XL, Cheng YM, Shi BS, Qian FX, Wang FB, Liu XN, Yang HY, Xu QN, Qi TK,
Zha LJ, Yuan ZH*, Ghildyal R.Measles virus infection in adults induces production of
IL-10 and is associated with increased CD4+ CD25+ regulatory T cells.. J Immunol
2008;181:7356-7366.
2. Chen Z, Cheng YM, Xu YF, Liao J, Zhang XN, Hu YW, Zhang Q, Wang JF, Shen F,
Yuan ZH*. Expression profiles and function of Toll-like receptors 2 and 4 in peripheral
blood mononuclearcells of chronic hepatitis B patients. Clin Immunol 2008;128:400-8
3. Lin SH, Wu M, Xu Y, Xiong W, Yi ZG, Zhang XN, Yuan ZH*. Inhibition of Hepatitis
B virus replication by MyD88 is mediated by nuclear factor-kappaB activation. BBAMolecular
Basis of Disease 2007;1772:1150–1157
4. Wu M, Xu Y, Lin SH, Zhang XN, Li X, and Yuan ZH*. HBV polymerase inhibits the
interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1. J Gen
Virol 2007;88(Pt 12):3260-9.
5. Wang J, Tong W, Zhang X, Chen L, Yi Z, Pan T, Hu Y, Xiang L, Yuan Z*. Hepatitis C
virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in
Huh7 hepatoma cells. FEBS Lett. 2006;580(18):4392-400.
6. Fang CY, Yi ZG, Liu F, Lan SY, Wang JD, Lu HJ, Yang PY and Yuan ZH*. Proteome
analysis of human liver carcinoma Huh7 cells harboring hepatitis C virus subgenomic
replicon. Proteomics 2006;6(2):519-27.
7. Liu L, Zhou X, Liu H, Xiang L, Yuan Z*. CpG motif acts as a 'danger signal' and
provides a T helper type 1-biased microenvironment for DNA vaccination. Immunology
2005;115(2):223-30.
8. Wei Xiong, Xun Wang, Xiaoying Liu, Li Xiang, Lingjie Zheng, Zhenghong Yuan*.
Interferon-inducible MyD88 Protein Inhibits Hepatitis B Virus Replication. Virology
2004;319(2):306-314.
9. Ling Liu, Xiaohui Zhou, Zhengong Yuan*. Toll-like receptor-9 induced by physical
trauma mediates release of cytokines following exposure to CpG motif in mouse skin.
Immunology 2003;110:341-347.
10. Shuiyun Lan, Hua Wang, Hong Jiang, Hongxia Mao, Xiaoying Liu, Xiaonan
Zhang,Yunwen Hu, Li Xiang, Zhenghong Yuan*. FEBX Letters 2003;554(3):289-294