Subproject A3

Curriculum vitae
	Univ.-Prof. Dr. med. Joachim Fandrey
Date of birth:	March 30, 1960
Place of birth:	in Kiel, Germany
Work address:	Institut für Physiologie
	University of Duisburg-Essen, Medical School
	Hufelandstr. 55 / IG1
	45122 Essen, Germany
	Tel.: +49 (0) 201 723-4600, Fax: +49 (0) 201 723-4648
	e-mail: joachim.fandrey@uk-essen.de
Academic education and qualifications:
1981-1983	Christian-Albrecht-Universität, Kiel
Aug. 1983	Ärztliche Vorprüfung (Preclinical exam)
1983-1985	Medizinische Universität zu Lübeck
1985-1986	Universität Wien
1986-1988	Medizinische Universität zu Lübeck
Apr. 1986	Scholar of the Studienstiftung des Deutschen Volkes
1987-1988	Final Year (Lübeck, London, Zürich)
Jul. 1987	American Medical Exam (ECFMG 1 + 2)
Jun. 1988	Final Medical Exam, License as physician (Approbation)
Professional appointments:
1988-1990:	Institut für Physiologie, Medizinische Universität zu Lübeck
May 1989:	Doctoral degree in Physiology (Dr. med.) "summa cum laude"
1990:	Lecturer in Physiology, Dept. Physiology, University of Khartoum, Sudan (Stipendium of the DAAD)
1990-1991	Scholar of the Deutsche Forschungsgemeinschaft, Postdoctoral Fellow at Prof. H. Franklin Bunn, Harvard Medical School, Boston, MA, U.S.A.
1991-1996	Postdoctoral fellow, Physiologisches Institut I, University of Bonn
28.06.1995	Habilitation "Physiologie und Pathophysiologie der sauerstoffabhängigen Bildung des Hormons Erythropoietin"
1996-1999	Senior lecturer in Physiology (Hochschuldozent) Institut für Physiologie, Medizinischen Universität zu Lübeck
since 1999	Full Professor (C4) of Physiology, Director

 

Selected publications Joachim Fandrey

1. Berchner-Pfannschmidt U, Yamac H, Trinidad B, Fandrey J (2007). Nitric Oxide Modulates Oxygen Sensing by Hypoxia-inducible Factor 1-dependent Induction of Prolyl Hydroxylase. J. Biol. Chem. 282: 1788-1796

2. Wotzlaw C, Otto T, Berchner-Pfannschmidt U, Metzen E, Acker H, Fandrey J (2007). Optical analysis of the HIF-1 complex in living cells by FRET and FRAP. FASEB J. 21: 700-707

3. Ehrentraut S, Frede S, Stapel H, Mengden T, Grohé C, Fandrey J, Meyer R, Baumgarten G (2007). Antagonism of Lipopolysaccharide-Induced Blood Pressure Attenuation and Vascular Contractility. Arterioscler Thromb Vasc Biol : 2170-2176

4. Severino A, Campioni M, Straino S, Salloum F N, Schmidt N, Herbrand U, Frede S, Toietta G, di Rocco G, Bussani R, Silvestri F, Piro M, Liuzzo G, Biasucci L M, Mellone P, Feroce F, Capogrossi M, Baldi F, Fandrey J, Ehrmann M, Crea F, Abbate A, Baldi A (2007). Identification of Protein Disulfide Isomerase as a Cardiomyocyte Survival Factor in Ischemic Cardiomyopathy. J Am Coll Cardiol 50: 1029-037

5. Horbelt M, Wotzlaw C, Sutton TA, Molitoris BA, Philipp T, Kribben A, Fandrey J, Pietruck F (2007). Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy. Kidney Int. 72:422-9

6. Otto T and Fandrey J (2008). Thyroid Hormone Induces Hypoxia-Inducible Factor 1a Gene Expression through Thyroid Hormone Receptor β/Retinoid X Receptor a-Dependent Activation of Hepatic Leukemia Factor. Endocrinology 149: 2241-2250

7. Berchner-Pfannschmidt U, Frede S, Wotzlaw C, Fandrey J (2008). Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing. European Respiratory J 32: 210-217

8. Berchner-Pfannschmidt U, Tug S, Trinidad B, Oehme F, Yamac H, Wotzlaw C, Flamme I, Fandrey J (2008). Nuclear Oxygen Sensing: Induction of Endogenous Prolyl-hydroxylase 2 Activity by Hypoxia and Nitric Oxide. J Biol Chem 283: 31745-31753

9. Berchner-Pfannschmidt U, Tug S, Trinidad B, Becker M, Oehme F, Flamme I, Fandrey J, Kirsch M (2008). The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments. J Pineal Research 45: 489-496

10. Frede S, Stockmann C, Winning S, Freitag P, Fandrey J. (2009). HIF-1a accumulation and HIF-target gene expression are impaired after induction of endotoxin tolerance. J Immunol 182: 6470-6476