Subproject A5
Curriculum vitae |
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Helmut E. Meyer, Prof. Dr. |
Date of birth: |
28th December 1948 |
Place of birth: |
Salzwedel |
Work address: |
Medizinisches Proteom-Center (MPC) |
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Zentrum für klinische Forschung |
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Ruhr-Universitaet Bochum |
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Universitaetsstr. 150 |
| 44801 Bochum, Germany | |
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Tel. +49 234 32 22427 Fax +49 234 32 14554 |
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Academic education and qualifications: |
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1969 - 1974 |
Study of Biochemistry, Eberhard-Karls-Universität Tübingen |
1974 - 1976 |
Graduate Student, Ruhr-Universität Bochum Promotion, Ph.D. summa cum laude |
1989 |
Habilitation; PD, University of Bochum |
1995 |
Extraordinary Professor |
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Professional appointments: |
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1976 - 1977 |
Postdoctoral Fellow, Ruhr-Universität Bochum, Institute for Physiological Chemistry |
1977 - 1978 |
Employee of Roha Arzneimittel, Pharmaceutical Company, Bremen |
| 1978 - 1984 | Research Associate at the Diabetes Research Institute, Düsseldorf |
| 1985 - 1992 | Postdoctoral Fellow, Leader of the Protein Analytical Group, Institute for Physiological Chemistry, University of Bochum |
| 1992 - 1998 | Hochschuldozent, Medical Faculty, University of Bochum |
1999 – present |
Director of the Medical Proteom-Center, Ruhr-University Bochum |
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Awards and honours:
1967 Carl-Still Preis
2006 Erfinderpreis der Rubitec für die Entdeckung von Biomarkern bei Leberentzündungen
2007 Transferpreis der Rubitec GmbH und der Ruhr-Universität Bochum
Selected publications
Wichtige Publikationen 2004-2009
1. Milenkovic D, Kozjak V, Wiedemann N, Lohaus C, Meyer HE, Guiard B, Pfanner N und Meisinger C (2004) Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability. J. Biol. Chem. 279: 22781-85
2. Meisinger C, Rissler M, Chacinska A, Sanjuan Szklarz LK, Milenkovic D, Kozjak KV, Schönfisch B, Lohaus C, Meyer HE, Yaffe MP, Guiard B, Wiedemann N und Pfanner N (2004) The mitochondrial morphology protein mdm10 functions in assembly of the preprotein translocase of the outer membrane. Dev. Cell. 7: 61-71
3. Chacinska A, Lind M, Frazier AE, Dudek J, Meisinger C, Geissler A, Sickmann A, Meyer HE, Truscott KN, Guiard B, Pfanner N und Rehling P (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120: 817-29
4. Tribl F, Gerlach M, Marcus K, Asan E, Tatschner T, Arzberger T, Meyer HE, Bringmann G und Riederer P (2005) "Subcellular proteomics" of neuromelanin granules isolated from the human brain. Mol. Cell. Prot. 4: 945-57
5. Sitek B, Luttges J, Marcus K, Kloppel G, Schmiegel W, Meyer HE, Hahn SA und Stuhler K (2005) Application of fluorescence difference gel electrophoresis saturation labelling for the analysis of microdissected precursor lesions of pancreatic ductal adenocarcinoma. Proteomics 5: 2665-79
6. Chamrad D und Meyer HE (2005) Valid data from large-scale proteomics studies. Nat Methods 2, 647-8
7. Wiedemann N, Urzica E, Guiard B, Müller H, Lohaus C, Meyer HE, Ryan MT, Meisinger C, Mühlenhoff U, Lill R und Pfanner N (2006) Essential role of Isd11 in mitochondrial iron–sulfur cluster synthesis on Isu scaffold proteins. EMBO J. 25: 184-95
8. Hamacher M, Apweiler R, Arnold G, Becker A, Blüggel M, Carette O, Colvis C, Dunn MJ, Fröhlich T, Fountoulakis M, van Hall A, Herberg F, Ji J, Kretzschmar H, Lewczuk P, Lubec G, Marcus K, Martens L, Palacios Bustamante N, Park YM, Pennington SR, Robben J, Stuhler K, Reidegeld KA, Riederer P, Rossier J, Sanchez JC, Schrader M, Stephan C, Tagle D, Thiele H, Wang J, Wiltfang J, Yoo JS, Zhang C, Klose J, und Meyer HE (2006) HUPO Brain Proteome Project: Summary of the pilot phase and introduction of a comprehensive data reprocessing strategy. Proteomics 6: 4890-8
9. Meyer HE und Stühler K (2007) High-performance proteomics as a tool in biomarker discovery. Proteomics 7: 18-26
10. Mölleken C, Sitek B, Henkel C, Poschmann G, Sipos B, Wiese S, Warscheid B, Broelsch C, Reiser M, Friedman SL, Tornøe I, Schlosser A, Klöppel G, Schmiegel W, Meyer HE, Holmskov U, und Stühler K (2009) Detection of novel biomarkers of liver cirrhosis by proteomic analysis, Hepatology, . 2009 Apr;49(4):1257-66.