Welcome to ZMB
Aktuelle Veröffentlichung in "PNAS"
Revolution in der Gen-Forschung
[02.02.2010] Ein Forschungsprojekt der Professorin Ann Ehrenhofer-Murray am Zentrum für Medizinische Biotechnologie (ZMB) der Universität Duisburg-Essen zur Kontrolle der Genexpression hat jetzt die renommierte Fachzeitschrift „Proceedings of the National Academy of Science“ (Nationale Akademie der Wissenschaften der USA) aufmerksam werden lassen. Die Wissenschaftlerin berichtet in der Publikation über die entscheidende Rolle zweier Enzyme bei der Genexpression.
» Zur Pressemitteilung "Revolution in der Gen-Forschung."
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Nature Veröffentlichung September 2009 - Breaking down Alzheimer's
Nature video with master's student in Medical Biology Simon Pöpsel - Immuntherapie bei chronischen Virusinfektionen
Neuer Deutsch-Chinesischer Sonderforschungsbereich Transregio 60
Recent Publications
Ehrentraut S, Weber JM, Dybowski JN, Hoffmann D, Ehrenhofer-Murray AE. Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate. PNAS Jan 2010.
Machacek M, Hodgson L, Welch C, Elliott H, Pertz O, Nalbant P, Abell A, Johnson GL, Hahn KM, Danuser G. Coordination of Rho GTPase activities during cell protrusion. Nature 2009;461(7260):99-103.
Küppers R. The Biology of Hodgkin lymphoma. Nat Rev Cancer. 2009 Jan;9(1):15-27. Epub 2008 Dec 11. Review.
Veldhoen M, Uyttenhove C, van Snick J, Helmby H, Westendorf A, Buer J, Martin B, Wilhelm C, Stockinger B. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol. 2008 Dec;9(12):1341-6. Epub 2008 Oct 19.
Bargou R, Leo E, Zugmaier G, Klinger M, Goebeler M, Knop S, Noppeney R, Viardot A, Hess G, Schuler M, Einsele H, Brandl C, Wolf A, Kirchinger P, Klappers P, Schmidt M, Riethmüller G, Reinhardt C, Baeuerle PA, Kufer P. Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science. 2008 Aug 15;321(5891):974-7.
Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, Renauld JC, Stockinger B. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature. 2008 May 1;453(7191):106-9. Epub 2008 Mar 23.
Krojer T, Sawa J, Schäfer E, Saibil HR, Ehrmann M, Clausen T. Structural basis for the regulated protease and chaperone function of DegP. Nature. 2008 Jun 12;453(7197):885-90. Epub 2008 May 21.
Groll M, Schellenberg B, Bachmann AS, Archer CR, Huber R, Powell TK, Lindow S, Kaiser M, Dudler R. A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism. Nature. 2008 Apr 10;452(7188):755-8.Teichgräber V, Ulrich M, Endlich N, Riethmüller J, Wilker B, De Oliveira-Munding CC, van Heeckeren AM, Barr ML, von Kürthy G, Schmid KW, Weller M, Tümmler B, Lang F, Grassme H, Döring G, Gulbins E. Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med. 2008 Apr;14(4):382-91. Epub 2008 Mar 30.
Gronwald W, Hohm T, Hoffmann D. Evolutionary Pareto-optimization of stably folding peptides.BMC Bioinformatics. 2008 Feb 19;9:109.
ZMB Publications 2007
Job Advertisement
Professorship, BesGr. W3 in "In vivo Imaging"
The University of Duisburg-Essen, Centre for Medical Biotechnology (ZMB), invites applications for a Professorship, BesGr. W3 in "In vivo Imaging".
1 Postdoctoral / 2 PhD Positions available
in Molecular Biology and Developmental Biology.
About us
The Centre for Medical Biotechnology (ZMB) is an interdisciplinary scientific centre of the University of Duisburg-Essen, integrating medical research at the University Hospital and natural sciences at the Campus.
The mission of the ZMB is to elucidate molecular mechanisms of disease and to turn this knowledge into medical progress. To this end the ZMB is active in key areas of basic biomedical research, and in the translation of scientific knowledge into novel drugs and diagnostic tools. Accordingly, the 40 groups of the ZMB combine basic and applied Biomedical Sciences.
Research is structured into four interdisciplinary programmes with numerous links between these programmes.
A dynamic, stimulating and collaborative research environment includes state of the art facilities and more than 300 highly educated personnel. Our interdisciplinary research crosses traditional boundaries and involves joint projects with the biotechnical and pharmaceutical industry, nanotechnology, physics and engineering.
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