Publications see also MEDLINE for the last publications up till 2003

2001 Tiedemann,H., Asashima, M., Grunz, H and Knoechel, W. (2001) Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate embryogenesis. Develop. Growth Diff. 43, 469-502

2001 Zhao, H., Cao,Y., and Grunz, H(2001) Isolation and characterization of a Xenopus gene (XMLP) encoding a MARCKS-like protein. Int.J.Dev.Biol. 45: 817-826

2001 Cao Y, Zhao H, Grunz H. (2001) XCL-2 is a novel m-type calpain and disrupts morphogenetic movements during embryogenesis in Xenopus laevis. Dev Growth Differ. 2001 Oct;43(5):563-71.

2001 Cao Y, Zhao H, Hollemann T, Chen Y, Grunz H. (2001) Tissue-specific expression of an Ornithine decarboxylase paralogue, XODC2, in Xenopus laevis. Mech Dev. :102(1-2):243-6.

2001 Zhao H, Cao Y, Grunz H.(2001) Expression of Xenopus L-arginine:glycine amidinotransferase (XAT) during early embryonic development. Dev Genes Evol. :211(7):358-60.

2001 Grunz, H. (2001). Developmental bioloy of amphibians after Hans Spemann in Germany. Int. J. Dev. Biol. 45: 39-50 in: Special Issue: The Spemann-Mangold Organizer - 75 Years On.

2000 Chen, Y., Hollemenann, T., Pieler, T. and Grunz,H. (2000) Planar signalling is not sufficient to generate a specific anterior/posterior neural pattern in pseudoexogastrula explants from Xenopus and Triturus. Mechanisms of Development 90, 53-63.

1999 Grunz,H. (1999) Gene expression and pattern formation during early embryonic development in amphibians. J.Biosci., 24, 4, 515-528.

1999 Grunz, H.(1999). Amphibian embryos as a model system for organ engineering: in vitro induction and recue of the heart anlage. Int.J.Dev.Biol. 43: 361-364.

1999 Piccolo, S., Agius, E., Bhattacharyya, S., Grunz, H., Bouwmeester, T., DeRobertis, E.M.(1999 ).The head-inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature, Vol. 397, 707-710.

1999 Chen, Y., Hollemann, T., Grunz, H. and Pieler, T. (1999). Characterizati-on of the ets-type protein ER81 in Xenopus embryos. Mechanisms of Development 80 (1), 67-76.

1998 Hollemann, T.; Chen, Y. L.; Grunz, H., and Pieler, T. Regionalized metabolic activity establishes boundaries of retinoic acid signalling. EMBO Journal. DEC 15 1998; 17(24): 7361-7372.

1998 Tiedemann, H.; Asashima, M.; Grunz, H.; Knoechel, W., and Tiedemann, H. Neural induction in embryos - Review. Development Growth & Differentiation. AUG 1998; 40(4): 363-376.

1997 Chen, Y. L. and Grunz, H. The final determination of Xenopus ectoderm depends on intrinsic and external positional information. International Journal of Developmental Biology. 1997; 41(3): 525-528.

1997 Penzel, R., Oschwald, R., Chen, Y. L.; Tacke, L.; Grunz, H (1997). Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis.International Journal of Developmental Biology,41(5): 667-677.

1997 Grunz,H. (1997) Neural Induction in Amphibians. in: Current Topics in Developmental Biology. Vol. 35, 191-228. Eds. Roger Pedersen and Gerald Schatten. Academic Press. San Diego, London, Boston, New York, Sydney, Tokyo, Toronto.

1997 Chen, Y. and Grunz,H. (1997) The final determination of Xenopus ectoderm depends on intrinsic and external positional information. Int.J.Dev.Biol. 41, 525-528

1996 Grunz, H. (1996) Factors responsible for the establishment of the body plan in the amphibian embryo. In the special issue: of Int.J.Dev.Biol.:" Developmental Biology in Germany", Eds.: M. Trendelenburg and H.Grunz

1996 Grunz, H. (1996) The long road to chemical and molecular embryology.What amphibians can teach us on differentiation. An interview with Professor Heinz Tiedemann. In the special issue: of Int.J.Dev.Biol.:" Developmental Biology in Germany", Eds.: M. Trendelenburg and H.Grunz

1996 Li, S., Mao, Z., Shaoyi, Y., Grunz, H. (1996) Isolated dorsal animal blastomeres of Xenopus laevis are capable to form mesodermal derivatives, while the ventral animal blastomeres differentiate into ciliated epidermis only. Zoological Sience 13,125-131.

1996 Grunz, H. (1996) Factors responsible for the establishment of the body plan in the amphibian embryo. In the special issue: of Int.J.Dev.Biol.: " Developmental Biology in Germany", Eds.: M. Trendelenburg and H.Grunz1995 Tiedemann, H., Tiedemann, H., Grunz, H. and Knšchel ,W. (1995). Molecular mechanisms of tissue determination and pattern formation in amphibian embryos. Naturwissenschaften 82:123-134.

1995 Grunz, H., SchŸren, C. and Richter, K. (1995). The role of vertical and planar signals during the early steps of neural induction. International Journal of Developmental Biology 39:539-543.

1995 Mikhailov, A.T., Gorgolyuk, N.A., Tacke, L., Mykhoyan, M.M. and Grunz, H. (1995). Partially purified factor from embryonic chick brain can provoke neuralization of Rana temporaria and Triturus alpestris but not Xenopus laevis early gastrula ectoderm. International Journal of Developmental Biology 39:317-325.

1995 Tiedemann, H., Tiedemann, H., Grunz, H. and Kn šchel, W. (1995). Molecular mechanisms of tissue determination and pattern formation in amphibian embryos. Naturwissenschaften 82:123-134.

1994 DelPino, E.M., Alcocer, I. And Grunz, H. (1994). Urea Is Necessary for the Culture of Embryos of the Marsupial Frog Gastrotheca Riobambae, and Is Tolerated by Embryos of the Aquatic Frog Xenopus Laevis. Development Growth and Differentiation 36:73-80.

1994 Grunz, H. (1994). The four animal blastomeres of the eight-cell stage of Xenopus laevis are intrinsically capable of differentiating into dorsal mesodermal derivatives. International Journal of Developmental Biology 38:69-76.

1994 Tiedemann, H., Grunz, H., Loppnowblinde, B. and Tiedemann, H. (1994). Basic fibroblast growth factor can induce exclusively neural tissue in Triturus ectoderm explants. Rouxs Archives of Developmental Biology 203:304-309.

1993 Grunz, H. (1993). The dorsalization of Spemann's organizer takes place during gastrulation in Xenopus laevis embryos. Develop. Growth & Differ. 35:21a28.

1993 Oschwald, R., Clement, J.H., Knšchel, W. And Grunz, H. (1993). Suramin Prevents Transcription of Dorsal Marker Genes in Xenopus-laevis Embryos, Isolated Dorsal Blastopore Lips and Activin-A Induced Animal Caps. Mechanisms of Development 43:121-133.

1992 1992 Grunz, H. (1992) Suramin changes the fate of Spemann's organizer and prevents neural induction in Xenopus laevis. Mechanisms of Development, 38, 133-142.

1992 Ding, Xiao-yan, McKeehan, W. L., Xu, J. and Grunz, H. (1992) Spatial and temporal localization of FGF receptors in Xenopus laevis. Roux's Arch Dev Biol 201, 334-339.

Lopashov, G. V., Selter, H., Montenarh, M., Knšchel, W., Grunz, H., Tiedemann, H. and Tiedemann, H. (1992) Neural inducing factors in neuroblastoma and retinoblastoma cell lines. Naturwissenschaften, 79, 365-367.

1991 Oschwald, R., Richter, K. and Grunz, H. (1991) Localization of a nervous system-specific class II ߧ-tubulin gene in Xenopus laevis embryos by whole-mount in situ hybridization. Int. J. of Developmental Biology, 35, 399-405.

1990 Grunz, H. and Tacke, L. (1990 ) Extracellular Matrix Components Prevent Neural Differentiation of Disaggregated Xenopus Ectoderm Cells. Cell Differentiation and Development, 32, 117-124.

1990 Grunz H (1990) †ber die Anwendung des Auflichtpolarisations- verfahrens mit dem Filtersystem Pol im PLOEMOPAK zur ein- deutigen Identifizierung von Silberkšrnern in Autoradiographien bei der in situ - Hybridisierungs-Technik. Mitt. f.Wissenschaft und Technik IX, 243-245

1990 Grunz H (1990) Epi-Polarization with the Leitz PLOEMOPAK, an excellent tool for the identification of silver grains in autoradiography after in situ - Hybridization. Scientific and Technical Information IX,7, 243 -245.

1990 Grunz H(1990) The Role of Inducing Factors in Early Embryonic Development. ONTOGENEZ, 21, 229 - 241

1990 Tacke L, Grunz H (1990) Effect of cytochalasin B, Nocodazol and procaine on binding and fate of concanavalin A in competent ectoderm of Xenopus laevis Zoological Science 7, 657-670

1990 Grunz, H. (1990) Epi-Polarisation with the PLOEMOPAK (Leitz), an excellent tool for the identification of silver grains in autoradiography after in situ-Hybridisation . Scientific and Technical Information IX, 7 , 243-245.

Grunz, H. (1990) The role of inducing factors in early embryonic development. Ontogenez, 21, 229-241.

1990 Tacke, L. and Grunz, H. (1990 ) Effect of Cytochalasin-B, Nocodazol and Procaine on Binding and Fate of Concanavalin-A in Competent Ectoderm of Xenopus laevis. Zoological Science, 7, 657-670.

1990 Grunz, H. and Tacke, L. (1990 ) Extracellular Matrix Components Prevent Neural Differentiation of Disaggregated Xenopus Ectoderm Cells. Cell Differentiation and Development, 32, 117-124.

1990 Grunz, H. (1990 ) Homoiogenetic neural inducing activity of the presumptive neural plate of Xenopus laevis. Development Growth and Differentiation, 32, 583-589.

1989 1989 Grunz H, Tacke L (1989) Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Diff. and Develop. 28, 211-218

1989 Grunz H, Born J, Davids M,Hoppe P, Loppnow-Blinde B, Tacke L, Tiedemann H, Tiedemann H (1989) A mesoderm-inducing factor from a Xenopus laevis cell line: Chemical properties and relation to the vegetalizing factor from chicken embryos. Roux'Arch Dev Biol 198, 8-13

1989 Grunz H, Tacke L (1989) Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Diff. and Develop. 28, 211-218

1989 Knšchel W, Grunz H, Loppnow-Blinde B, Tiedemann H, Tiedemann H (1989) Mesoderm induction and blood island formation by angiogenic growth factors and embryonic inducing factors. Blut 59, 207 - 213

1988 Grunz H, Mc Keehan W, Knšchel W, Born J, Tiedemann H, Tiedemann H (1988) Induction of mesodermal tissues by acidic and basic heparin binding growth factors. Cell Differentiation, 22, 183-190

1988 Tacke L, Grunz H (1988) Close juxtaposition between inducing chordamesoderm and reacting neuroectoderm is a prerequisite for neural induction in Xenopus laevis. Cell Differentiation 24, 33-44

1988 Brahma S K, Grunz H (1988) Immunofluorescence localization of cristallins in Xenopus laevis free lens development. Wilhelm Roux' Arch. Dev. Biol. 197, 190-192

1988 Tiedemann H, Grunz H, Mc Keehan W,Knšchel W, Born J, Hoppe P,Loppnow-Blinde B, Tiedemann H, Volk R. (1988) Growth factors and their receptors: Genetic control and rational application. J. Cell Biochem. Suppl. 12A

1988 Rosa F, Sargent T D, Rebbert M L, Michaels G S, Jamrich MM, Grunz H, Jonas E, Winkles J A, Dawid I B (1988) Accumulation and decay of DG42 gene products follow a gradient pattern during Xenopus embryogenesis. Developmental Biology 129, 114-123

1988 Richter K, Grunz H, Dawid I B (1988) Gene expression in the embryonic nervous system of Xenopus laevis. Proc. Natl. Acad. Sci. USA 85, 8086-8090

1987 Grunz H , Darribere T, Boucaut J C (1987) Binding of anti-fibronectin to early amphibian ectoderm does not result in inhibition of neural induction under in vitro conditions. Roux' Arch. Dev. Biol. 196, 203-209

1987 Grunz H (1987) The importance of inducing factors for determination, differentiation and pattern formation in early amphibian development. Zoological Science, 4, 579-591.

1987 Knšchel W, Born J, HoppeE P, Loppnow-Blinde B, Tiedemann H, Tiedemann H, Mc Keehan W,Grunz H (1987) Mesoderm inducing factor: Their possible relationship to heparin binding growth factors and transforming growth factor-§. Naturwissenschaften 74, 604-606

1986 Grunz H, Born J, Tiedeamnn H, Tiedemann H (1986) The activation of a neuralizing factor in the neural plate is correlated to its homoiogenetic inducing activity. Roux' Arch. Dev. Biol. 195, 464-466

1986 Tacke L, Grunz H (1986) Electron microscopy study of the binding of Con A-gold to superficial and inner ectoderm layers of Xenopus laevis in correlation to the neural inducing activity of this lectin. Roux' Arch. Dev. Biol. 195, 158-167

1986 Grunz H, Tacke L (1986) Embryonic induction in amphibians. in: New Discoveries and Technologies; Alan R. Liss Inc.; New York, pp. 135-138

1986 Tacke L, Grunz H (1986) Cell contacts between inducing tissue and target cells during neural induction. in: New Discoveries and Technologies; Alan R. Liss Inc.; New York, Part A, pp. 143-146

1986 Grunz H, Tacke L (1986) The inducing capacity of the presumptive endoderm of Xenopus laevis studied by transfilter experiments. Roux' Arch. Dev. Biol. 195, 467-473

1985 Grunz H (1985) Effect of Concanavalin A and vegetalizing factor on the outer and inner ectoderm layers of early gastrulae of Xenopus laevis after treatment with Cytochalasin B. Cell Differentiation 16, 83-92

1985 Siegel G, Grunz H, Grundmann U, Tiedemann H, Tiedemann H (1985) Independence of primary embryonic induction from changes in cation concentration. Cell Differentiation 17, 209-219

Grunz H (1985) Information transfer during embryonic induction in amphibians. J. Embryol. exp. Morph. 89, Supl., pp. 349-363

1985 Grunz H (1985) New aspects of early embryonic induction in amphibians. in: Sato G. H. et al (eds.); From Embryos to Cells: Hormonal Control of Differentiation; First International Symposium on Cellular Endocrinology, Lake Placid, Alan R. Liss Inc., New York, 45-54

1985 Grunz H (1985) VerŠnderung morphologischer und molekularbiologischer Prozesse wŠhrend der Embryonalentwicklung von Amphibien unter Mikro-g-Bedingungen. in: Gravitationsbiologie in der Bundesrepublik Deutschland. DFVLR-Mitt. 85-16, 75-80

1983 Grunz H (1983) Change in the differentiation pattern of Xenopus laevis ectoderm by variation of the incubation time and concentration of vegetalizing factor. Wilhelm Roux' Arch. 192, 130-137

1983 Grunz H (1983) Early embryonic induction. The ectodermal target cells. in: The role of cell interactions in early neurogenesis. Duprat, Kato, Weber, eds.; Plenum Press, Series A: Life Science, Vol. II, p. 21-38

1983 Grunz H (1983) Early embryonic induction in amphibians, a model system of the information transfer between cells. In: Developmental Biology. An Afro-Asian Perspective. S C Goel, R Bellairs, eds., pp. 73-86

1981 Feierabend J, Grunz H, Sauer H W (1981) Regulation of differentiation in eukaryotic model systems. European J. Cell Biol. 24, 157-159

Asashima M, Grunz H (1983) Effects of inducers on inner and outer gastrula ectoderm layers of Xenopus laevis. Differentiation 23, 157-159

1980 Grunz H (1980) A new method for the isolation of plasma membranes from amphibian embryos. Wilhelm Roux' Arch. 188, 87-89

1980 Minuth M, Grunz H (1980) The formation of mesodermal derivates after induction with vegetalizing factor depends on secondary cell interactions. Cell Differentiation 9, 229-238

1980 Born J, Grunz H, Tiedemann H, Tiedemann H (1980) Biological activity of the vegetalizing factor: decrease after coupling to polysaccharide matrix and enzymatic recovery of active factor. Wilhelm Roux' Arch. 189, 47-56

1979 Grunz H, Staubach J (1979) Change of the surface charge of ectodermal cells after induction. Wilhelm Roux' Arch. 186, 77-80

1979 Grunz H, Staubach J (1979) Cell contacts between chorda-mesoderm and the overlaying neuroectoderm (presumptive central nervous system) during the period of primary embryonic induction in amphibians. Differentiation 14, 59-65

1979 Wittig B, Wittig S, Grunz H (1979) Cloning of chicken embryo tRNA genes using single stranded nucleosomal DNA highly enriched for tRNA complementary sequences. Nucleid Acid Res. 6, 12, 3759-3772

1979 Grunz H (1979) Change of the differentiation pattern of amphibian ectoderm after the increase of the initial cell mass. Wilhelm Roux' Arch. 187, 49-57

1978 Grunz H (1978) The isolation and mode of action of early embryonic morphogenetic factors. Ontogenez. 9, 323-332

1978 Grunz H (1978) Principles and mechanisms of early embryonic induction and differentiation. Ontogenez. 9, 427-438

1978 Grunz H (1978) Induction and differentiation in early amphibian embryos. Plenarvortrag, XIII. International Embryological Conference, Berlin

1977 Grunz H (1977) The differentiation of the four animal and the four vegetal blastoderms of the eight-cell-stage of Triturus alpestris. Wilhelm Roux' Arch. 181, 267-277

1977 Grunz H, Tiedemann H (1977) Influence of cyclic nucleotides on amphibian ectoderm. Wilhelm Roux' Arch. 181, 261-165

1976 Grunz H (1976) Changes of cell surface and determination of amphibian ectoderm after induction. in: Proceedings of the Sixth European Congress on Electron Microscopy, Jerusalem, Vol. II, 571-573; Biological Science, Y. Ben-Shaul, ed.; Tal International Publishing Company

1975 Grunz H,Multier A M, Herbst R, Arkenberg G (1975) The differentiation of isolated amphibian ectoderm with or without treatment of an inductor. A scanning electron microscop study. Wilhelm Roux' Arch. 178, 277-284

1975 Rogge H, Neses M, Passow H, Grunz H, Risse H-J (1975) Studies of membraneous and nuclear glycosyltransferases in Dictyostelium cells during differentiation. in: New approaches to the evaluation of abnormal embryonic development; D. Neubert et al, eds; G. Thieme Verl. Stuttgart, p. 772-91

1975 Grunz H (1975) Studies on early embryonic induction and differentiation. in: New approaches to the evaluation of abnormal embryonic development; D. Neubert and H. Merker, eds., Georg Thieme Publishers, Stuttgart, p. 792-803

1974 1974 Pollow K, SokolowskiI G, Grunz H, Pollow B (1974) Hydroxysteroid-Oxidoreduktasen und ihre Funktion als Katalysatoren des spezifischen Wasserstoff-Transfers zwischen Steroidhormonen in Humanplacenta. Hoppe-Seyler's Z. Physiol. Chem. 555, 501-514

1973 1973 Grunz, H (1973) The ultrastructure of amphibian ectoderm treated with an inductor or actinomycin D. Wilhelm Roux' Arch. 173, 283-293
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1973 1973 Pollow K, Runge W, Pollow B, Grunz H, Willems W, Schmalbeck J (1973) PhospholipidabhŠngigkeit, Anreicherung und Charakterisierung der mikrosomalen 17§-Hydroxysteroid-Oxidoreduktase und der "TranshydrogenaseaktivitŠt" aus der Humanplacenta. Hoppe-Seyler's Z. Physiol. Chem. 354, 705-21

1972 1972 Grunz, H, Yamada, T (1972) Studies on cell affinity in the Wolffian lens regeneration system. Annual Report of the Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

1972 1972 Grunz, H (1972) Einflu§ von Inhibitoren der RNS- und Proteinsynthese und Induktoren auf die ZellaffinitŠt von Amphibiengewebe. Wilhelm Roux' Arch. 169, 41-55

1972 1972 Perdue, S W, Grunz H (1972) Feulgen-DNA-microspectro-photometry of Wolffian lens regeneration. Annual Report of the Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

1970 1970 Grunz, H (1970) AbhŠngigkeit der Kompetenz des Amphibien-Ektoderms von der Proteinsynthese. Roux'Arch.Dev.Biol. 165, 91-102

1969 1969 Grunz, H (1969) Hemmung der Reaggregation dissoziierter Amphibienzellen durch Inhibitoren der RNS- und Proteinsynthese. Roux' Arch. Dev.Biol. 163, 184-196

1968 1968 Grunz, H. (1968) Experimentelle Untersuchungen Ÿber die KompetenzverhŠltnisse frŸher Entwicklungsstadien des Amphibien-Ektoderms. Roux'Arch.Dev.Biol. 160, 344-374