The European Society of Endocrinology (ESE) honors Senior Professor Dr. Josef Köhrle, LOCOTACT PI, Institute of Experimental Endocrinology, Charité - University Hospital Berlin, with the European Hormone Medal 2022. This is awarded to an international scientist who has made significant research contributions in the field of basic or clinical endocrinology.
He receives this award for basic research in the field of endocrinology and for his commitment to the promotion of young endocrinologists.
The award ceremony will follow the plenary lecture "Great impact in low quantities - thyroid hormones, trace elements and endocrine disruptors" at the European Congress of Endocrinology, ECE 2022 in Milan. read more

 

We congratulate Prof. Dr. Kirstina Lorenz, LOCOTACT PI, who has been awarded with the PHOENIX Research Award 2021 in the category Pharmacology and Clinical Pharmacy!

The awarding of this prestigious prize is based on Prof. Lorenz' research published in Nature Commun in 2020, "Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects".

More information about the research and the award can be found here. Video of the award ceremony.

 

We thank Prof. Jan G. Hengstler for his excellent talk in the November edition of the LOCOTACT Lectures!

 

The audience has been highly impressed by the innovative technique to visualize liver cells intravitally.

PD Dr. Anna Cirkel, LOCOTACT PI, is the winner of the Renate-Maaß-Research Award in 2021!

With this esteemed award the Renate-Maaß-Foundation in Lübeck recognizes the outstanding work of Dr. Cirkel in studying the influence of thyroid hormone on brain function, memory formation and behaviour. More information about the research of Dr. Cirkel and the Award can be found here.

Prof. Heike Heuer, LOCOTACT PI, is the 2021 British Thyroid Association Pitt-Rivers Lecturer!

She will give her Medal Lecture about the “Role of thyroid hormone transporters in brain development and function” on Monday November 8 at 14:00 GMT at the SfE BES 2021 in Edinburgh.

The Society for Endocrinology interviewed Prof. Heuer about her career, her inspirations, challenges and future visions in TH research. Follow this link to read the whole interview.

Congratulations to this renowned award!

We are pleased to announce the final program for the LOCOTACT Lectures in the winter semester 2021/22!

 

04.11.2021, 5.00 pm

Prof. Dr. Jan G. Hengstler, Leibniz Research Centre for Working Environment and Human Factors, Dortmund

 

09.12.2021, 5.00 pm

Dr. Gad Vatine, The Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev

 

13.01.2022, 5.00 pm

Prof. Dr. Matthias Gunzer, Institute for Experimental Immunology and Imaging, University of Duisburg-Essen

 

10.02.2022, 5.00 pm

Prof. Miguel López Pérez, Center for Research in Molecular Medicine and Chronic Diseases, University of Santiago de Compostela

 

You can download the flyer here.

Many thanks to Guo Huang for his impressive presentation to kick off the LOCOTACT Lectures.

 

Especially for the young scientists of our CRC the lectures has been a great inspiration and motivation!

 

Guo Huang enjoyed all discussions and interactions about his talk.

We would like to congratulate two award winners of our LOCOTACT consortium!

 

Junior group leader and LOCOTACT PI Dr. Steffen Mayerl was awarded with the ETA Jack Robbins Prize for his presentation on the role of thyroid hormone transporters in GABAergic interneuron development.

 

Ann-Kathrin Schörding, MD student in the group of Prof. Lars Moeller received the prestigious Young Investigator Award for her outstanding presentation on canonical thyroid hormone action in bone development.

 

Thanks to everyone who actively paticipated and represented our consortium during the meeting!

Only a few days are left until the opening of the European THYROID Association eConference 2021!

 

It is our great pleasure to announce six speakers of the LOCOTACT consortium:

 

Dr. Robert Opitz, Charité – Universitätsmedizin Berlin - Saturday (04.09.) Oral Session I: 01:00 PM - 02:45 PM

Dr. Steffen Mayerl, Universitätsklinikum Essen - Sunday (05.09.) Oral Session II: 06:15 PM – 07:15 PM

Prof. Jens Mittag, Universität zu Lübeck - Monday (06.09.) Scientific Symposium 6: 02:00 PM - 03:00 PM

Ann-Kathrin Schörding, Universitätsklinikum Essen - Tuesday (07.09.) Young Investigator Session: 02:00 PM – 03:00 PM

Dr. Janina Pape (née Gassen), Universitätsklinikum Essen - Tuesday (07.09.) Young Investigator Session: 02:00 PM – 03:00 PM

Dr. Sebastian Hönes, Universitätsklinikum Essen - Tuesday (07.09.) Oral Session 4: 04:15 PM – 05:15 PM

 

You can view the full programme here or download it here.

The monthly lectures with invited guest speakers start on September 9, 2021 and will take place on thursdays from 5:00 to 6:00 pm via Zoom.

The first iRTG Workshop is going to take place in Münster from 25^th to 27^th of November 2021.

 

We could win Jeremiah Hendren for a 2-days Scientific Writing Workshop.

Detailed programme information are following soon.

We warmly welcome four young scientists in LOCOTACT who successfully applied for iRTG MD Fellowships!

 

Audrey Bresser will investigate TH regulation of neuronal development in human cerebral organoids (Project 04; PI: Prof. Peter Kühnen).

Livia Hoerner will study selenium-contanining proteins as biomarkers of tissue function and damage (Project 17; PI: Prof. Lutz Schomburg).

Jonas Rotter will analyse the function and expression of thyroid hormone transporters in the elderly and in patients with neurodegenerative diseases (Project 03; PI: Prof. Ingo Bechmann).

Wiebke Werner will unravel the immune microenvironment of non-alcoholic fatty liver disease in the context of local thyroid hormone metabolism (Project 15; PI: Prof. Frank Tacke)

 

We are pleased that the project of Dr. Steffen Mayerl on "Impact of thyroid hormone transport on seizure generation" is now part of LOCOTACT as Project 19. 

 

In this project, Dr. Mayerl and his team will investigate the pathogenic mechanisms underlying the increased seizure susceptibility of human MCT8 patients.

 

To this end, they will address the importance of TH transporters for different neuronal populations as well as the consequences of seizure induction in TH transporter deficiency and their role in the transition to epilepsy. 

The 1^st LOCOTACT annual retreat was a great success with thrilling talks and discussions in Zoom and Gather.Town. 

Four outstanding poster presentations by our young scientists were honoured with awards: 

 

It‘s our great pleasure to announce that we could win Dr. W. Edward Visser as the Keynote Speaker for our Retreat!

 

We are looking forward to an excellent talk, thrilling discussions and fruitful Meet the Keynote Speaker Sessions.

Topic: "MCT8 deficiency: diagnosis and therapy"

June 03-04, 2021

Online Congress

March 03-05, 2021

Online Congress

January 29, 2021

M.Sc. Irina Kube (Essen) erhielt auf der 26. Jahrestagung der Nordrhein-Westfälischen Gesellschaft für Endokrinologie & Diabetologie den Karl-Oberdisse-Preis für ihre Studien zur Gallensteinentstehung unter Hypothyreose - Wir gratulieren herzlich!

Die einen sind ständig müde, unkonzentriert und frieren leicht, die anderen klagen über Herzrasen, Schlaflosigkeit und Hitzewallungen.

 

Hinter beidem steckt oftmals eine Erkrankung der Schilddrüse. Jeder dritte Deutsche leidet im Verlaufe seines Lebens an einer Schilddrüsenveränderung.

 

Das kleine Organ unterhalb des Kehlkopfes wird häufig unterschätzt. Dabei lenkt es viele wichtige Funktionen im Körper.

Die nur 25 Gramm schwere Schilddrüse liegt wie ein Schmetterling an der Vorderseite des Halses - und sie ist eine richtige Hormonfabrik.

 

Sie beeinflusst Stoffwechsel und Wachstum, stärkt die Knochen und reguliert das seelische Wohlbefinden.

 

Und: Sie sie ist ein zentraler Faktor für die Leistungsfähigkeit unseres Gehirns.

Prof. Dr. Peter Kühnen (Charité, Berlin) ist für seine Studien zur Normalisierung des Körpergewichtes mit dem renommierten Paul- Martini-Preis ausgezeichnet worden - Wir gratulieren herzlich!

Topics were

Ein neuer Sonderforschungsbereich führt nun einen Perspektivwechsel durch, der Angebot und Nachfrage von Schilddrüsenhormonen in den jeweiligen Organen unter die Lupe nimmt.

 

Insbesondere neue Erkenntnisse zu molekularbiologischen Prozessen und den Einfluss der lokalen Schilddrüsenhormonwirkung in Gehirn, Leber und Herz sollen ein Licht auf die Krankheitsentstehung werfen und neue Therapieansätze ermöglichen.