November 2021European Hormone Medal 2022

The European Society of Endocrinology (ESE) honors Senior Professor Dr. Josef Köhrle, LOCOTACT PI, Institute of Experimental Endocrinology, Charité - University Hospital Berlin, with the European Hormone Medal 2022. This is awarded to an international scientist who has made significant research contributions in the field of basic or clinical endocrinology.
He receives this award for basic research in the field of endocrinology and for his commitment to the promotion of young endocrinologists.
The award ceremony will follow the plenary lecture "Great impact in low quantities - thyroid hormones, trace elements and endocrine disruptors" at the European Congress of Endocrinology, ECE 2022 in Milan. read more
Congratulations to Prof. Dr. Josef Köhrle!

November 18, 2021PHOENIX Pharmazie Wissenschaftspreis 2021

We congratulate Prof. Dr. Kirstina Lorenz, LOCOTACT PI, who has been awarded with the PHOENIX Research Award 2021 in the category Pharmacology and Clinical Pharmacy!
The awarding of this prestigious prize is based on Prof. Lorenz' research published in Nature Commun in 2020, "Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects".
More information about the research and the award can be found here. Video of the award ceremony.
The picture shows Prof. Kristina Lorenz and the other PHOENIX Research Awardees 2021.

November 4, 2021LOCOTACT Lectures - Jan G. Hengstler

We thank Prof. Jan G. Hengstler for his excellent talk in the November edition of the LOCOTACT Lectures!
The audience has been highly impressed by the innovative technique to visualize liver cells intravitally.

October 27, 2021Renate-Maaß-Research Award 2021

PD Dr. Anna Cirkel, LOCOTACT PI, is the winner of the Renate-Maaß-Research Award in 2021!
With this esteemed award the Renate-Maaß-Foundation in Lübeck recognizes the outstanding work of Dr. Cirkel in studying the influence of thyroid hormone on brain function, memory formation and behaviour. More information about the research of Dr. Cirkel and the Award can be found here.
Congratulations to PD Dr. Anna Cirkel!

October 13, 2021Interview with the 2021 Pitt-Rivers Lecturer

Prof. Heike Heuer, LOCOTACT PI, is the 2021 British Thyroid Association Pitt-Rivers Lecturer!
She will give her Medal Lecture about the “Role of thyroid hormone transporters in brain development and function” on Monday November 8 at 14:00 GMT at the SfE BES 2021 in Edinburgh.
The Society for Endocrinology interviewed Prof. Heuer about her career, her inspirations, challenges and future visions in TH research. Follow this link to read the whole interview.
Congratulations to this renowned award!

2021-22LOCOTACT Lectures - Final Programme

We are pleased to announce the final program for the LOCOTACT Lectures in the winter semester 2021/22!
04.11.2021, 5.00 pm
Prof. Dr. Jan G. Hengstler, Leibniz Research Centre for Working Environment and Human Factors, Dortmund
“Intravital functional imaging of the liver: elucidation of pathophysiological mechanisms of steatohepatitis“
09.12.2021, 5.00 pm
Dr. Gad Vatine, The Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev
13.01.2022, 5.00 pm
Prof. Dr. Matthias Gunzer, Institute for Experimental Immunology and Imaging, University of Duisburg-Essen
“Neutrophils in sterile and infectious inflammation“
10.02.2022, 5.00 pm
Prof. Miguel López Pérez, Center for Research in Molecular Medicine and Chronic Diseases, University of Santiago de Compostela
“Obesity Wars: a New Hope, hypothalamic AMPK targeting“
You can download the flyer here.

Sep 9, 2021LOCOTACT Lectures - Guo Huang

Many thanks to Guo Huang for his impressive presentation to kick off the LOCOTACT Lectures.
Especially for the young scientists of our CRC the lectures has been a great inspiration and motivation!
Guo Huang enjoyed all discussions and interactions about his talk.

Sep 4-7, 202143rd annual ETA eConference 2021

We would like to congratulate two award winners of our LOCOTACT consortium!
Junior group leader and LOCOTACT PI Dr. Steffen Mayerl was awarded with the ETA Jack Robbins Prize for his presentation on the role of thyroid hormone transporters in GABAergic interneuron development.
Ann-Kathrin Schörding, MD student in the group of Prof. Lars Moeller received the prestigious Young Investigator Award for her outstanding presentation on canonical thyroid hormone action in bone development.
Thanks to everyone who actively paticipated and represented our consortium during the meeting!

Sep 4-7, 202143rd annual ETA eConference 2021

Only a few days are left until the opening of the European THYROID Association eConference 2021!
It is our great pleasure to announce six speakers of the LOCOTACT consortium:
Dr. Robert Opitz, Charité – Universitätsmedizin Berlin - Saturday (04.09.) Oral Session I: 01:00 PM - 02:45 PM
Dr. Steffen Mayerl, Universitätsklinikum Essen - Sunday (05.09.) Oral Session II: 06:15 PM – 07:15 PM
Prof. Jens Mittag, Universität zu Lübeck - Monday (06.09.) Scientific Symposium 6: 02:00 PM - 03:00 PM
Ann-Kathrin Schörding, Universitätsklinikum Essen - Tuesday (07.09.) Young Investigator Session: 02:00 PM – 03:00 PM
Dr. Janina Pape (née Gassen), Universitätsklinikum Essen - Tuesday (07.09.) Young Investigator Session: 02:00 PM – 03:00 PM
Dr. Sebastian Hönes, Universitätsklinikum Essen - Tuesday (07.09.) Oral Session 4: 04:15 PM – 05:15 PM
You can view the full programme here or download it here.

Sep 9, 2021 - 5.00 pmLOCOTACT-Lectures

The monthly lectures with invited guest speakers start on September 9, 2021 and will take place on thursdays from 5:00 to 6:00 pm via Zoom.
It is our great pleasure to announce our first Speaker:
Guo Huang, Ph.D from the University of California, San Francisco. Guo Huang is an expert in regeneration of cardiomyocytes, regenerative potential vs. thermogenesis, evolution and the role of thyroid hormones Huang Lab at UCSF

Nov 25-27, 2021iRTG Workshop in Münster

The first iRTG Workshop is going to take place in Münster from 25th to 27th of November 2021.
We could win Jeremiah Hendren for a 2-days Scientific Writing Workshop.
Detailed programme information are following soon.

July 01, 2021Four MD Fellowships within our iRTG

We warmly welcome four young scientists in LOCOTACT who successfully applied for iRTG MD Fellowships!
Audrey Bresser will investigate TH regulation of neuronal development in human cerebral organoids (Project 04; PI: Prof. Peter Kühnen).
Livia Hoerner will study selenium-contanining proteins as biomarkers of tissue function and damage (Project 17; PI: Prof. Lutz Schomburg).
Jonas Rotter will analyse the function and expression of thyroid hormone transporters in the elderly and in patients with neurodegenerative diseases (Project 03; PI: Prof. Ingo Bechmann).
Wiebke Werner will unravel the immune microenvironment of non-alcoholic fatty liver disease in the context of local thyroid hormone metabolism (Project 15; PI: Prof. Frank Tacke)
Good Luck with your projects!

June 04, 2021New LOCOTACT Project

We are pleased that the project of Dr. Steffen Mayerl on "Impact of thyroid hormone transport on seizure generation" is now part of LOCOTACT as Project 19
In this project, Dr. Mayerl and his team will investigate the pathogenic mechanisms underlying the increased seizure susceptibility of human MCT8 patients.
To this end, they will address the importance of TH transporters for different neuronal populations as well as the consequences of seizure induction in TH transporter deficiency and their role in the transition to epilepsy. 

June 03-04, 2021LOCOTACT Online-Retreat

The 1st LOCOTACT annual retreat was a great success with thrilling talks and discussions in Zoom and Gather.Town
Four outstanding poster presentations by our young scientists were honoured with awards: 
  • Anna Molenaar (Project 05)
  • Daniel Ullrich (Project 08)
  • Nuria López Alcántara (Project 14)
  • Rajas Sane and Joshua Seifert (Project 16)

June 03-04, 2021LOCOTACT Online-Retreat

It‘s our great pleasure to announce that we could win Dr. W. Edward Visser as the Keynote Speaker for our Retreat!
We are looking forward to an excellent talk, thrilling discussions and fruitful Meet the Keynote Speaker Sessions.
Topic: "MCT8 deficiency: diagnosis and therapy"

June 03-04, 2021Internal Meeting

LOCOTACT Online-Retreat

June 03-04, 2021

March 03-05, 2021External Meeting

64. Deutscher Kongress für Endokrinologie (DGE)

Online Congress
March 03-05, 2021

January 29, 2021External Meeting

22. Annual Meeting YARE

Online Congress
January 29, 2021


January 29, 2021Karl-Oberdisse-Preis für M.Sc. Irina Kube

M.Sc. Irina Kube (Essen) erhielt auf der 26. Jahrestagung der Nordrhein-Westfälischen Gesellschaft für Endokrinologie & Diabetologie den Karl-Oberdisse-Preis für ihre Studien zur Gallensteinentstehung unter Hypothyreose - Wir gratulieren herzlich!

December 17, 2020Schilddrüse – das unterschätzte Organ

Die einen sind ständig müde, unkonzentriert und frieren leicht, die anderen klagen über Herzrasen, Schlaflosigkeit und Hitzewallungen.
Hinter beidem steckt oftmals eine Erkrankung der Schilddrüse. Jeder dritte Deutsche leidet im Verlaufe seines Lebens an einer Schilddrüsenveränderung.
Das kleine Organ unterhalb des Kehlkopfes wird häufig unterschätzt. Dabei lenkt es viele wichtige Funktionen im Körper.

December 01, 2020Schilddrüse: Mehr Hirn durch Jod? Interview

Die nur 25 Gramm schwere Schilddrüse liegt wie ein Schmetterling an der Vorderseite des Halses - und sie ist eine richtige Hormonfabrik.
Sie beeinflusst Stoffwechsel und Wachstum, stärkt die Knochen und reguliert das seelische Wohlbefinden.
Und: Sie sie ist ein zentraler Faktor für die Leistungsfähigkeit unseres Gehirns.

23. November 2020Auszeichnung für LOCOTACT-Forscher Prof. Peter Kühnen

Prof. Dr. Peter Kühnen (Charité, Berlin) ist für seine Studien zur Normalisierung des Körpergewichtes mit dem renommierten Paul- Martini-Preis ausgezeichnet worden - Wir gratulieren herzlich!
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October 5th, 2020The CRC/TR296 kick-off meeting took place via Zoom

Topics were
  • Approval of bylaws by CRC/TR296 member assembly
  • Election of steering commitee members
  • Current status of Z-projects

19. Juni 2020, Informationsdienst Wissenschaft (idw), Pressemitteilung DDG/DGEParadigmenwechsel in der Schilddrüsen-Forschung könnte Therapie von Schlaganfall und Herzinfarkt voranbringen

Ein neuer Sonderforschungsbereich führt nun einen Perspektivwechsel durch, der Angebot und Nachfrage von Schilddrüsenhormonen in den jeweiligen Organen unter die Lupe nimmt.
Insbesondere neue Erkenntnisse zu molekularbiologischen Prozessen und den Einfluss der lokalen Schilddrüsenhormonwirkung in Gehirn, Leber und Herz sollen ein Licht auf die Krankheitsentstehung werfen und neue Therapieansätze ermöglichen.
Learn more