NeuroScienceLab Essen
Britta Kaltwasser

Biotechnical Assistant
Office: MFZ, 2nd floor, room 2.036
Phone: +49 201 723 1663
Fax: +49 201 723 6903

Britta Kaltwasser completed her education as a Biology Lab Assistant at the University of Göttingen in 1994. Her professional activities as research technician started at the Institute of Humangenetics in Göttingen, followed by trainings and stays in research & development units of biomedical companies. Britta Kaltwasser gathered first experience in stroke research at the Department for Neurology of the University Hospital Göttingen. She then joined the Chair of Vascular Neurology, Dementia and Ageing Research and NeuroScienceLab in November 2010.
Research interests

Techniques and methods used by Britta Kaltwasser include, but are not restricted to cell and stem cell culture, immunohistochemistry, Western blotting, ELISA and PCR.
Key publications

Doeppner TR, Kaltwasser B, Sanchez-Mendoza EH, Caglayan AB, Bähr M, Hermann DM. Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3β inhibition-independent pathways. J Cereb Blood Flow Metab. 2017; 37(3):914-926.

Hermann DM, Zechariah A, Kaltwasser B, Bosche B, Caglayan AB, Kilic E, Doeppner TR. Sustained neurological recovery induced by resveratrol is associated with angioneurogenesis rather than neuroprotection after focal cerebral ischemia. Neurobiol Dis. 2015; 83:16-25.

Doeppner TR, Pehlke JR, Kaltwasser B, Schlechter J, Kilic E, Bähr M, Hermann DM. The indirect NMDAR antagonist acamprosate induces postischemic neurologic recovery associated with sustained neuroprotection and neuroregeneration. J Cereb Blood Flow Metab. 2015; 35(12):2089-97.

Doeppner TR, Kaltwasser B, Fengyan J, Hermann DM, Bähr M. TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells. J Cereb Blood Flow Metab. 2013; 33(11):1778-88.

Doeppner TR, Doehring M, Bretschneider E, Zechariah A, Kaltwasser B, Müller B, Koch JC, Bähr M, Hermann DM, Michel U. MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation Acta Neuropathol. 2013; 126(2):251-65.

Doeppner TR, Mlynarczuk-Bialy I, Kuckelkorn U, Kaltwasser B, Herz J, Hasan MR, Hermann DM, Bähr M. The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis Brain. 2012; 135(Pt 11):3282-97.

Doeppner TR, Kaltwasser B, ElAli A, Zechariah A, Hermann DM, Bähr M. Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation. J Cereb Blood Flow Metab. 2011; 31(5):1251-62.
NeuroScienceLab Sekretariat