NeuroScienceLab Essen
Matthias Pilath-Eilers, MSc

PhD student
Office: MFZ, 2nd floor, room 2.031
Phone: +49 201 723 1660
Fax: +49 201 723 6903

Matthias Pilath-Eilers studied biology at the Heinrich Heine University Düsseldorf and received his Bachelors degree in 2018 for a thesis investigating changes in extracellular potassium homeostasis evoked by Gamma aminobutyric acid in mouse hippocampus. Matthias finished his master degree in 2021. He conducted his thesis at the NeuroScienceLab, investigating the effect of interleukin activated microglia on synapses of primary neuron-astrocyte co-cultures as well as live cell imaging of GCaMP6f astrocytes to study the effect of activated microglia on astrocytic calcium signalling.
Research interests

Ischemic stroke not only affects the BBB and astrocytes but also alters the integrity of extracellular matrix (ECM). Changes in ECM reach from rearrangements after mild hypoperfusion to degradation after focal cerebral ischaemia and are closely related to reactive astrocytes. It is expected that the interplay between ECM and astrocytes is important for the formation of new synapses, yet the question how astrocytes detect changes in the ECM remains open. Potentially, the ECM-astrocyte interaction is mediated by mechanoreceptors, but their role in post stroke brain remodelling remains unknown.
NeuroScienceLab Sekretariat