NeuroScienceLab Essen
Dr. rer. nat. Stine Mencl

Post-doctoral scientist/Lab Manager
Office: IG1, 9th floor, room 9.002
Phone: +49 201 723 82854
Fax: +49 201 723 79030

Stine Mencl studied Biology at the University of Hohenheim in Stuttgart and received her diploma at the Institute of Zoology in 2008. As a PhD student at the "Graduate School of Cellular & Molecular Neuroscience", she studied murine retinal neurodegeneration models in the division of experimental Ophthalmology (University Hospital Tübingen), where she finished her PhD thesis in 2012. Joining the group of Prof. Kleinschnitz as a postdoctoral fellow at the Department of Experimental Neurology (University Hospital of Würzburg), she traded the eye for the brain. When Prof. Kleinschnitz became chair of the Neurology Clinic at the Essen University Hospital and founded the NeuroScienceLab in 2016, she moved to Essen to support the lab and teach students.
Research interests

Stine Mencl investigates neurodegenerative disorders like stroke, stroke-related heart failure, and cerebral air embolism.
Key publications

Rohlfing AK, Kolb K, Sigle M, ..., Mencl S, ..., Gawaz M. Ackr3 regulates platelet activation and ischemia-reperfusion tissue injury. Nature communications. 2022;13:1823

Rolfes L, Ruck T, David C, Mencl S, ..., Meuth SG. Natural killer cells are present in rag1(-/-) mice and promote tissue damage during the acute phase of ischemic stroke. Translational stroke research. 2022;13:197-211

Koeniger T, Bell L, Mifka A, ..., Mencl S, ..., Kuerten S. Bone marrow-derived myeloid progenitors in the leptomeninges of adult mice. Stem Cells. 2021;39:227-239

Bieber M, Gronewold J, Scharf AC, ..., Mencl S, ..., Hermann DM. Validity and reliability of neurological scores in mice exposed to middle cerebral artery occlusion. Stroke. 2019;50:2875-2882

Hopp S, Albert-Weissenberger C, Mencl S, ..., Kleinschnitz C. Targeting coagulation factor xii as a novel therapeutic option in brain trauma. Annals of neurology. 2016;79:970-982

Kleinschnitz C, Mencl S, Kleikers PWM, ..., Schmidt H. Nos knockout or inhibition but not disrupting psd-95-nos interaction protect against ischemic brain damage. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016;36:1508-1512

Mencl S, Hennig N, Hopp S, ..., Kleinschnitz C. Fty720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation. Journal of neuroimmunology. 2014;274:125-131

Mencl S, Garz C, Niklass S, Niklass S, ..., Kleinschnitz C, Schreiber S. Early microvascular dysfunction in cerebral small vessel disease is not detectable on 3.0 tesla magnetic resonance imaging: A longitudinal study in spontaneously hypertensive stroke-prone rats. Experimental & translational stroke medicine. 2013;5:8
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