ZMB Member Matthias Gunzer

Prof. Dr. Matthias Gunzer
Phone
+49 201 183 6640
Email
Medical Faculty (Campus Essen)
Room S05 V01 E29
University of Duisburg-Essen
45141 Essen
Research Overview
The research interest of my group is to characterize the dynamics of immune cell behaviour, their motility and migratory pattern as well as formation of cell-cell interaction within the course of the immune response in vivo. My lab employs a wide range of specialized imaging technologies by which we investigate a number of projects how immune cells function in vivo in important organs such as the lymph node, the bone marrow, the brain and the lung.

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Interview with Professor Gunzer as part of a video introducing the Centre for Medical Biotechnology (ZMB).
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Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigrationIn: Journal of Experimental Medicine (JEM) Vol. 218 (2021) Nr. 1, pp. e20192378
ISSN: 1540-9538; 0022-1007Online Full Text: dx.doi.org/ -
Advances in the in vivo molecular imaging of invasive aspergillosisIn: Journal of Fungi Vol. 6 (2020) Nr. 4, pp. 338
ISSN: 2309-608XOnline Full Text: dx.doi.org/ (Open Access) -
Co-option of Neutrophil Fates by Tissue EnvironmentsIn: Cell Vol. 183 (2020) Nr. 5, pp. 1282 - 1297.e18
ISSN: 1097-4172; 0092-8674Online Full Text: dx.doi.org/ -
Community standards for open cell migration dataIn: GigaScience Vol. 9 (2020) Nr. 5, pp. giaa041
ISSN: 2047-217XOnline Full Text: dx.doi.org/ (Open Access) -
Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinibIn: BMC Cancer Vol. 20 (2020) Nr. 1, pp. 650
ISSN: 1471-2407Online Full Text: dx.doi.org/ (Open Access) -
Durable and controlled depletion of neutrophils in miceIn: Nature Communications Vol. 11 (2020) pp. 2762
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemiaIn: Basic Research in Cardiology Vol. 115 (2020) Nr. 6, pp. 64
ISSN: 1435-1803; 0300-8428Online Full Text: dx.doi.org/ (Open Access) -
Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signalingIn: Nature Communications Vol. 11 (2020) Nr. 1, pp. 3547
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically NeutrophilsIn: Stroke Vol. 9 (2020) Nr. 10, pp. 1825 - 1834
ISSN: 1524-4628; 0039-2499Online Full Text: dx.doi.org/ (Open Access) -
Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESSIn: Nature Protocols Vol. 15 (2020) pp. 1041 - 1065
ISSN: 1750-2799; 1754-2189Online Full Text: dx.doi.org/ -
Neutrophil dynamics, plasticity and function in acute neurodegeneration following neonatal hypoxia–ischemiaIn: Brain, Behavior, and Immunity (2020)
ISSN: 1090-2139; 0889-1591Online Full Text: dx.doi.org/ (Open Access) -
Non-classical monocyte homing to the gut via α4β7 integrin mediates macrophage-dependent intestinal wound healingIn: Gut Vol. 69 (2020) pp. 252 - 263
ISSN: 1468-3288; 0017-5749Online Full Text: dx.doi.org/ -
STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosisIn: Gut Vol. 69 (2020) Nr. 7, pp. 1269 - 1282
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Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer modelIn: Cancer Immunology, Immunotherapy Vol. 69 (2020) Nr. 10, pp. 2101 - 2112
ISSN: 1432-0851; 0340-7004Online Full Text: dx.doi.org/ (Open Access) -
The infectious propagules of Aspergillus fumigatus are coated with antimicrobial peptidesIn: Cellular Microbiology (2020) pp. e13301
ISSN: 1462-5822; 1462-5814Online Full Text: dx.doi.org/ (Open Access) -
Three-Dimensional Light Sheet Fluorescence Microscopy of Lungs To Dissect Local Host Immune-Aspergillus fumigatus InteractionsIn: mBio Vol. 11 (2020) Nr. 1, pp. e02752 - 19
ISSN: 2150-7511; 2161-2129Online Full Text: dx.doi.org/ (Open Access) -
Ventricular assist device for a coronavirus disease 2019-affected heartIn: ESC Heart Failure (2020) in press
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A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism Vol. 1 (2019) Nr. 2, pp. 236 - 250
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Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal CancerIn: Immunity Vol. 50 (2019) Nr. 1, pp. 166 - 180.e7
ISSN: 1097-4180; 1074-7613Online Full Text: dx.doi.org/ (Open Access) -
Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and responseIn: Nature Communications Vol. 10 (2019) Nr. 1, pp. 2312
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
Differential attenuation of β2 integrin-dependent and -independent neutrophil migration by Ly6G ligationIn: Blood Advances Vol. 3 (2019) Nr. 3, pp. 256 - 267
ISSN: 2473-9537; 2473-9529Online Full Text: dx.doi.org/ (Open Access) -
Distinct spatio-temporal dynamics of tumor-associated neutrophils in small tumor lesionsIn: Frontiers in Immunology Vol. 10 (2019) pp. 1419
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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and MetastasisIn: Cancer Cell Vol. 36 (2019) Nr. 3, pp. 319 - 336.e7
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Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell deathIn: Nature Vol. 569 (2019) Nr. 7755, pp. 236 - 240
ISSN: 0028-0836; 1476-4687Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related componentsIn: Protein & Cell Vol. 10 (2019) Nr. 1, pp. 60 - 66
ISSN: 1674-8018; 1674-800XOnline Full Text: dx.doi.org/ (Open Access) -
Infection of B Cell Follicle-Resident Cells by Friend Retrovirus Occurs during Acute Infection and Is Maintained during Viral PersistenceIn: mBio Vol. 10 (2019) Nr. 1,
ISSN: 2150-7511; 2161-2129Online Full Text: dx.doi.org/ (Open Access) -
Location of Neutrophils in Different Compartments of the Damaged Mouse Brain After Severe Ischemia/ReperfusionIn: Stroke: journal of the American Heart Association Vol. 50 (2019) Nr. 6, pp. 1548 - 1557
ISSN: 1524-4628; 0039-2499; 0749-7954Online Full Text: dx.doi.org/ -
Microglial cell loss after ischemic stroke favors brain neutrophil accumulationIn: Acta Neuropathologica Vol. 137 (2019) Nr. 2, pp. 321 - 341
ISSN: 1432-0533; 0001-6322Online Full Text: dx.doi.org/ (Open Access) -
Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissueIn: Science Immunology Vol. 4 (2019) Nr. 40,
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Next-generation imaging of the skeletal system and its blood supplyIn: Nature Reviews Rheumatology Vol. 15 (2019) Nr. 9, pp. 533 - 549
ISSN: 1759-4804; 1759-4790Online Full Text: dx.doi.org/ -
Polymorphonuclear Neutrophils Play a Decisive Role for Brain Injury and Neurological Recovery PoststrokeIn: Stroke Vol. 50 (2019) Nr. 3, pp. e40 - e41
ISSN: 1524-4628; 0039-2499Online Full Text: dx.doi.org/ -
Publisher Correction: Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and responseIn: Nature Communications Vol. 10 (2019) Nr. 1, pp. 2768
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
A systematic electron microscopic study on the uptake of barium sulphate nano-, submicro-, microparticles by bone marrow-derived phagocytosing cellsIn: Acta Biomaterialia Vol. 80 (2018) pp. 352 - 363
ISSN: 1878-7568; 1742-7061Online Full Text: dx.doi.org/ -
Beware the intruder : Real time observation of infiltrated neutrophils and neutrophil-Microglia interaction during stroke in vivoIn: PLoS ONE Vol. 13 (2018) Nr. 3, pp. e0193970
ISSN: 1932-6203Online Full Text: dx.doi.org/ (Open Access) -
Fine structure analysis to detect bone poresIn: Annals of the Rheumatic Diseases Vol. 77 (2018) Nr. Suppl. 2,
ISSN: 1468-2060; 0003-4967Online Full Text: dx.doi.org/ -
Gegenseitige Beeinflussung von Immunsystem und KnochenIn: Zeitschrift für Rheumatologie Vol. 77 (2018) Nr. Suppl. 1, pp. 8 - 11
ISSN: 0340-1855; 1435-1250Online Full Text: dx.doi.org/ -
How Safe Is the Administration of Long-Acting Granulocyte Colony-Stimulating Factor in Cancer Patients?In: Oncology Research and Treatment Vol. 41 (2018) Nr. 5, pp. 316 - 326
ISSN: 2296-5262; 2296-5270Online Full Text: dx.doi.org/ -
Imaging of cytotoxic antiviral immunity while considering the 3R principle of animal researchIn: Journal of Molecular Medicine Vol. 96 (2018) Nr. 3-4, pp. 349 - 360
ISSN: 0946-2716; 0946-2716Online Full Text: dx.doi.org/ -
Implications of polymorphonuclear neutrophils for ischemic stroke and intracerebral hemorrhage : Predictive value, pathophysiological consequences and utility as therapeutic targetIn: Journal of Neuroimmunology Vol. 321 (2018) pp. 138 - 143
ISSN: 1872-8421; 0165-5728Online Full Text: dx.doi.org/ -
Modeling hemolytic-uremic syndrome : In-depth characterization of distinct murine models reflecting different features of human diseaseIn: Frontiers in Immunology Vol. 9 (2018) pp. 1459
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Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunityIn: Nature Immunology Vol. 19 (2018) Nr. 12, pp. 1341 - 1351
ISSN: 1529-2916; 1529-2908Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Nanoparticle decoration impacts airborne fungal pathobiologyIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 115 (2018) Nr. 27, pp. 7087 - 7092
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ (Open Access) -
Neue Einblicke in die Funktion des KnochenmarksIn: Zeitschrift für Rheumatologie Vol. 77 (2018) Nr. Supplement 1, pp. 4 - 7
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Neutrophils instruct homeostatic and pathological states in naive tissuesIn: Journal of Experimental Medicine Vol. 215 (2018) Nr. 11, pp. 2778 - 2795
ISSN: 0022-1007; 1540-9538Online Full Text: dx.doi.org/ (Open Access) -
Rescue of T-cell function during persistent pulmonary adenoviral infection by Toll-like receptor 9 activationIn: The Journal of Allergy and Clinical Immunology Vol. 141 (2018) Nr. 1, pp. 416 - 419.e10
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Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation via Toll-Like Receptor 7In: Frontiers in Immunology Vol. 9 (2018) pp. 245
ISSN: 1664-3224Online Full Text: dx.doi.org/ (Open Access) -
Role of polymorphonuclear neutrophils in the reperfused ischemic brain : insights from cell-type-specific immunodepletion and fluorescence microscopy studiesIn: Therapeutic Advances in Neurological Disorders Vol. 11 (2018) pp. 1756286418798607
ISSN: 1756-2856; 1756-2864Online Full Text: dx.doi.org/ (Open Access) -
Surveillance of myelodysplastic syndrome via migration analyses of blood neutrophils : A potential prognostic toolIn: The Journal of Immunology Vol. 201 (2018) Nr. 12, pp. 3546 - 3557
ISSN: 0022-1767; 1550-6606Online Full Text: dx.doi.org/ -
3D visualization and quantification of microvessels in the whole ischemic mouse brain using solvent-based clearing and light sheet microscopyIn: Journal of Cerebral Blood Flow and Metabolism Vol. 37 (2017) Nr. 10, pp. 3355 - 3367
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Escaping the traps of your own huntersIn: Science Vol. 358 (2017) Nr. 6367, pp. 1126 - 1127
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Fully automated evaluation of total glomerular number and capillary tuft size in nephritic kidneys using lightsheet microscopyIn: Journal of the American Society of Nephrology Vol. 28 (2017) Nr. 2, pp. 452 - 459
ISSN: 1533-3450; 1046-6673Online Full Text: dx.doi.org/ -
Hepatitis B virus production is enhanced through early autophagic flux but degraded through autophagosome-lysosome fusionIn: Journal of Hepatology Vol. 66 (2017) Nr. 1, pp. S701
ISSN: 0168-8278; 1600-0641Online Full Text: dx.doi.org/ -
ICAM1+ neutrophils promote chronic inflammation via ASPRV1 in B cell-dependent autoimmune encephalomyelitis.In: JCI Insight Vol. 2 (2017) Nr. 23,
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Intravital lung imaging to study the interactions between immune cells and Aspergillus fumigatusIn: European Journal of Immunology Vol. 47 (2017) Nr. Suppl. 2, pp. 40 - 40
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Introduction of 2D human leucocyte migration assays suited for the application in the clinical setupIn: European Journal of Immunology Vol. 47 (2017) Nr. Suppl. 2, pp. 232
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Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileusIn: Gut Vol. 66 (2017) Nr. 12, pp. 2110 - 2120
ISSN: 1468-3288; 0017-5749Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Quantitative Visualization of Leukocyte Infiltrate in a Murine Model of Fulminant Myocarditis by Light Sheet MicroscopyIn: Journal of Visualized Experiments (2017) Nr. 123, pp. e55450
ISSN: 1940-087XOnline Full Text: dx.doi.org/ Online Full Text (Open Access) -
Quantitative analysis of proteome modulations in alveolar epithelial type II cells in response to pulmonary aspergillus fumigatus infectionIn: Molecular and Cellular Proteomics Vol. 16 (2017) Nr. 12, pp. 2184 - 2198
ISSN: 1535-9476; 1535-9484Online Full Text: dx.doi.org/ -
Three-Dimensional Cross-Sectional Light-Sheet Microscopy Imaging of the Inflamed Mouse GutIn: Gastroenterology Vol. 153 (2017) Nr. 4, pp. 898 - 900
ISSN: 1528-0012; 0016-5085Online Full Text: dx.doi.org/ -
Towards translational ImmunoPET/MR imaging of invasive pulmonary aspergillosis : The humanised monoclonal antibody JF5 detects aspergillus lung infections in vivoIn: Theranostics Vol. 7 (2017) Nr. 14, pp. 3398 - 3414
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Unexpected role of neutrophil granulocytes during both murine and human central nervous system autoimmunityIn: Multiple Sclerosis Journal Vol. 23 (2017) Nr. Suppl. 3, pp. 42
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Visualizing the function and fate of neutrophils in sterile injury and repairIn: Science Vol. 358 (2017) Nr. 6359, pp. 111 - 116
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Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived SignalsIn: mBio Vol. 7 (2016) Nr. 3,
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CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxinIn: European Journal of Immunology Vol. 46 (2016) Nr. 8, pp. 2028 - 2042
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ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivoIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 113 (2016) Nr. 8, pp. E1026 - E1033
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ (Open Access) -
Neutrophil Migration into the Infected Uroepithelium Is Regulated by the Crosstalk between Resident and Helper MacrophagesIn: Pathogens Vol. 5 (2016) Nr. 1,
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Survival of residual neutrophils and accelerated myelopoiesis limit the efficacy of antibody-mediated depletion of Ly-6G+ cells in tumor-bearing miceIn: Journal of Leukocyte Biology Vol. 99 (2016) Nr. 6, pp. 811 - 823
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Catchup : a mouse model for imaging-based tracking and modulation of neutrophil granulocytesIn: Nature Methods Vol. 12 (2015) Nr. 5, pp. 445 - 452
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Clinical application of noninvasive and nonradioactive determination of microscopic lymph node tumor status by multispectral optoacoustic imagingIn: Journal of Nuclear Medicine Vol. 56 (2015) Nr. Suppl. 3, pp. 40
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Die multispektraloptoakustische Tomographie (MSOT) zur nichtinvasiven Diagnostik des Schildwächterlymphknotens bei Patienten mit malignem MelanomIn: Journal der Deutschen Dermatologischen Gesellschaft Vol. 13 (2015) Nr. 12, pp. 1323
ISSN: 1610-0379; 1610-0387Online Full Text: dx.doi.org/ -
Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imagingIn: Immunotherapy Vol. 7 (2015) Nr. 317, pp. 317ra199
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Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic MiceIn: Stroke Vol. 46 (2015) Nr. 10, pp. 2916 - 2925
ISSN: 0039-2499; 1524-4628Online Full Text: dx.doi.org/ (Open Access) -
Tracking phagocyte function in vivoIn: The Journal of Clinical Investigation Vol. 45 (2015) Nr. Suppl. 2, Special Issue: Abstracts of the 49th Annual Scientific Meeting of the European Society for Clinical Investigation Cluj‐Napoca, Romania 27 – 30 May 2015, pp. 48
ISSN: 0014-2972; 1365-2362Online Full Text: dx.doi.org/ -
Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental strokeIn: Acta Neuropathologica Vol. 129 (2015) Nr. 2, pp. 259 - 277
ISSN: 0001-6322; 1432-0533Online Full Text: dx.doi.org/ -
Correction: Automated Characterization and Parameter-Free Classification of Cell Tracks Based on Local Migration BehaviorIn: PLoS ONE Vol. 9 (2014) Nr. 12, pp. e115158
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Die Photooptoakustische Tomographie zur nicht invasiven und nicht radioaktiven Bestimmung des Schildw € achterlymphknotenstatus bei MelanompatientenIn: Journal der Deutschen Dermatologischen Gesellschaft Vol. 12 (2014) Nr. Suppl. 3, pp. 5 - 6
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Human dendritic cell subsets display distinct interactions with the pathogenic mould Aspergillus fumigatusIn: International Journal of Medical Microbiology Vol. 304 (2014) Nr. 8, pp. 1160 - 1168
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Traps and hyper inflammation - new ways that neutrophils promote or hinder survivalIn: British Journal of Haematology Vol. 164 (2014) Nr. 2, pp. 189 - 199
ISSN: 0007-1048; 1365-2141Online Full Text: dx.doi.org/ -
A role for LFA-1 in delaying T-lymphocyte egress from lymph nodesIn: The EMBO Journal Vol. 32 (2013) Nr. 6, pp. 829 - 843
ISSN: 1460-2075; 0261-4189Online Full Text: dx.doi.org/ -
Automated characterization and parameter-free classification of Cell tracks based on local migration behaviorIn: PLoS ONE Vol. 8 (2013) Nr. 12,
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Cellular immune reactions in the lungIn: Immunological Reviews Vol. 251 (2013) Nr. 1, pp. 189 - 214
ISSN: 0105-2896; 1600-065XOnline Full Text: dx.doi.org/ -
Dynamic crosstalk of neutrophil granulocytes and microglia at the ischemic blood-brain interface - role of very late antigen-4In: Cerebrovascular Diseases Vol. 35 (2013) Nr. Suppl. 3, pp. 27
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Imaging ImmunityIn: Vox Sanguinis Vol. 105 (2013) Nr. Suppl. 1, pp. 45
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Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammationIn: Blood Vol. 121 (2013) Nr. 24, pp. 4930 - 4937
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Multimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clustersIn: Molecular and Cellular Proteomics Vol. 12 (2013) Nr. 9, pp. 2551 - 2567
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Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal diseaseIn: mBio Vol. 4 (2013) Nr. 1, pp. e00535 - 12
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T cell activation results in conformational changes in the Src family kinase Lck to induce its activationIn: Science Signaling Vol. 6 (2013) Nr. 263,
ISSN: 1945-0877; 1937-9145Online Full Text: dx.doi.org/ -
TLR7 contributes to the rapid progression but not to the overall fatal outcome of secondary pneumococcal disease following influenza a virus infectionIn: Journal of Innate Immunity Vol. 5 (2013) Nr. 1, pp. 84 - 96
ISSN: 1662-8128; 1662-811XOnline Full Text: dx.doi.org/ -
Transiently Reduced PI3K/Akt Activity Drives the Development of Regulatory Function in Antigen-Stimulated Naïve T-CellsIn: PLoS ONE Vol. 8 (2013) Nr. 7, pp. e68378
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White-opaque switching of Candida albicans allows immune evasion in an environment-dependent fashionIn: Eukaryotic Cell Vol. 12 (2013) Nr. 1, pp. 50 - 58
ISSN: 1535-9778; 1535-9786Online Full Text: dx.doi.org/ -
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenationIn: Cell Stem Cell Vol. 10 (2012) Nr. 5, pp. 520 - 530
ISSN: 1875-9777; 1934-5909Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitorsIn: Blood Vol. 119 (2012) Nr. 22, pp. 5144 - 5154
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Functional roles for defective PI3K signaling and differing costimulatory activity of APCs in T-Cell plasticityIn: Immunology Vol. 137 (2012) Nr. Suppl. 1, pp. 408 - 409
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Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptensIn: Experimental Dermatology Vol. 21 (2012) Nr. 3, pp. e34 - e34
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Microglia-neutrophil interactions : A new field of application for the phagocytosis Marker pHrodoIn: Journal of Neuroimmunology Vol. 253 (2012) Nr. 1-2, pp. 100 - 101
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Multi-molecular three-dimensional analysis of the stable immunological synapse reveals sustained recruitment and sequential assembly of signaling clustersIn: Immunology Vol. 137 (2012) Nr. Suppl. 1, pp. 12 - 12
ISSN: 0019-2805; 1365-2567 -
Surface display of Gaussia princeps luciferase allows sensitive fungal pathogen detection during cutaneous aspergillosisIn: Virulence Vol. 3 (2012) Nr. 1, pp. 50 - 61
ISSN: 2150-5608; 2150-5594Online Full Text: dx.doi.org/ -
Taking neutrophils out of play in developing secondary neuronal damage after stroke by anti-VLA-4 treatmentIn: Journal of Neuroimmunology Vol. 253 (2012) Nr. 1-2, pp. 112 - 112
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Vaccine adjuvants : Tailor-made mast-cell granulesIn: Nature Materials Vol. 11 (2012) Nr. 3, pp. 181 - 182
ISSN: 1476-4660; 1476-1122Online Full Text: dx.doi.org/ -
CD8(+) T Cells regulate by means of their Perforin-Granula Systems of IgE Production in vitro by directly Killing the B CellsIn: Journal der Deutschen Dermatologischen Gesellschaft Vol. 9 (2011) Nr. Suppl. 1, pp. 130 - 131
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CD8(+) T cells regulate IgE-production in vitro via direct killing of B cells using their perforin-granule systemIn: Experimental Dermatology Vol. 20 (2011) Nr. 2, pp. 164
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Direct observation of phagocytosis and NET-formation by neutrophils in infected lungs using 2-photon microscopyIn: Journal of Visualized Experiments (2011) Nr. 52,
ISSN: 1940-087XOnline Full Text: dx.doi.org/ Online Full Text (Open Access) -
G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligandsIn: Blood Vol. 117 (2011) Nr. 16, pp. 4349 - 4357
ISSN: 0006-4971; 1528-0020Online Full Text: dx.doi.org/ -
Human Regulatory T Cells Rapidly Suppress T Cell Receptor-Induced Ca(2+), NF-kappa B, and NFAT Signaling in Conventional T CellsIn: Science Signaling Vol. 4 (2011) Nr. 204, pp. ra90
ISSN: 1937-9145Online Full Text: dx.doi.org/ -
Imaging hematopoietic stem cells in the marrow of long bones in vivoIn: Methods in Molecular Biology Vol. 750 (2011) pp. 215 - 224
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Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of HaptensIn: Immunity Vol. 34 (2011) Nr. 6, pp. 973 - 984
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On the way toward systems biology of Aspergillus fumigatus infectionIn: International Journal of Medical Microbiology Vol. 301 (2011) Nr. 5, pp. 453 - 459
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Phagocyte responses towards Aspergillus fumigatusIn: International Journal of Medical Microbiology Vol. 301 (2011) Nr. 5, pp. 436 - 444
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Rapid Immunomagnetic Negative Enrichment of Neutrophil Granulocytes from Murine Bone Marrow for Functional Studies In Vitro and In VivoIn: PLoS ONE Vol. 6 (2011) Nr. 2, pp. e17314
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Shaping the fungal adaptome--stress responses of Aspergillus fumigatusIn: International Journal of Medical Microbiology Vol. 301 (2011) Nr. 5, pp. 408 - 416
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Sphingosine 1-phosphate-induced motility and endocytosis of dendritic cells is regulated by SWAP-70 through RhoAIn: The Journal of Immunology Vol. 186 (2011) Nr. 9, pp. 5345 - 5355
ISSN: 0022-1767Online Full Text: dx.doi.org/ -
APC, T cells, and the immune synapseIn: Current Topics in Microbiology and Immunology Vol. 340 (2010) pp. 229 - 249
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Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodAIn: PLoS Pathogens Vol. 6 (2010) Nr. 4, pp. e1000873
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Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturationIn: Immunity Vol. 33 (2010) Nr. 1, pp. 84 - 95
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Data management plan for the project “Status determination of the sentinel lymph node via light sheet fluorescence microscopy”Duisburg, Essen (2019)
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A subset of mature neutrophils contains the strongest PMN-MDSC activity in blood and tissue of patients with head and neck cancer
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A subset of mature neutrophils contains the strongest PMN-MDSC activity in blood and tissue of patients with head and neck cancer
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Temporal changes in cellular sources of CXC chemokines control neutrophil recruitment during Citrobacter rodentium infection
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SP0106 Looking through my back boneIn: Annals of the Rheumatic Diseases Vol. 78 (2019) Nr. Suppl. 2, pp. 30 - 31
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The opportunistic pathogen Aspergillus fumigatus coats its infectious propagules with antimicrobial peptides
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