ZMB Member Andrea Musacchio

Andrea Musacchio

Prof. Dr. Andrea Musacchio

Phone
+49 231 133 2100
Email

Max-Planck-Institut für molekulare Physiologie
Otto-Hahn-Str. 11
44227 Dortmund

Department

Mechanistische Zellbiologie

Max Planck Institute of Molecular Physiology

Research Overview

  • Spindle assembly checkpoint components and functions
  • Spindle assembly checkpoint (SAC) signalling
  • Mitotic checkpoint complex (MCC)
  • Anaphase-promoting complex (APC/C)
  • Structural organization of the kinetochore
  • Analyses of localization dependencies of kinetochore proteins
  • Kinetochore receptors of checkpoint components
  • Kinetochore–microtubule attachment
  • Homeostatic control of mitotic arrest
  • Sensitivity of cancer cells to antitubulin chemotherapeutics