ZMB Member Perihan Nalbant, Publications

Prof. Dr. Perihan Nalbant

Selected Publications

Graessl M, Koch J, Calderon A, Kamps D, Banerjee S, Mazel T, Schulze N, Jungkurth JK, Patwardhan R, Solouk D, Hampe N, Hoffmann B, Dehmelt L, Nalbant P. 2017. An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns. Journal of Cell Biology. 216(12):4271-4285.

Jeruschke S, Jeruschke K, DiStasio A, Karaterzi S, Büscher AK, Nalbant P, Klein-Hitpass L, Hoyer PF, Weiss J, Stottmann RW, Weber S. 2015. Everolimus stabilizes podocyte microtubules via enhancing TUBB2B and DCDC2 expression. PLoS ONE. 10(9).

Nalbant P, Dehmelt L. 2018. Exploratory cell dynamics: A sense of touch for cells? Biological Chemistry. 399(8):809-819

Schulze N, Graessl M, Blancke Soares A, Geyer M, Dehmelt L, Nalbant P. FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibers. J Cell Sci. 2014 Apr 1;127(Pt 7):1379-93.

Jeruschke S, Büscher AK, Oh J, Saleem MA, Hoyer PF, Weber S, Nalbant P. Protective effects of the mTOR inhibitor everolimus on cytoskeletal injury in human podocytes are mediated by RhoA signaling. PLoS One. 2013;8(2):e55980. Epub 2013 Feb 13.

Machacek M, Hodgson L, Welch C, Elliott H, Pertz O, Nalbant P, Abell A, Johnson GL, Hahn KM, Danuser G. Coordination of Rho GTPase activities during cell protrusion. Nature 2009;461(7260):99-103.

Nalbant P, Chang YC, Birkenfeld J, Chang ZF, Bokoch GM. Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge. Mol Biol Cell 2009;20(18):4070-82.

Manukyan M, Nalbant P, Luxen S, Hahn KM, Knaus UG. RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B. J Immunol 2009;182(6):3522-9.

Chang YC, Nalbant P, Birkenfeld J, Chang ZF, Bokoch GM. GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA. Molecular Biology of the Cell 2008;19(5):2147-53.

Lim Y, Lim ST, Tomar A, Gardel M, Bernard-Trifilo JA, Chen XL, Uryu SA, Canete-Soler R, Zhai J, Lin H, Schlaepfer WW, Nalbant P, Bokoch G, Ilic D, Waterman-Storer C, Schlaepfer DD. PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. Journal of Cell Biology 2008;180(1):187-203.

Frantz C, Karydis A, Nalbant P, Hahn KM, Barber DL. Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells. Journal of Cell Biology 2007;179(3):403-10.

El-Sibai M, Nalbant P, Pang H, Flinn RJ, Sarmiento C, Macaluso F, Cammer M, Condeelis JS, Hahn KM, Backer JM. Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells. Journal of Cell Science 2007;120:3465-3474.

Birkenfeld J, Nalbant P, Bohl BP, Pertz O, Hahn KM, Bokoch GM. GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. Developmental Cell 2007;12(5): 699-712.

Zhao T, Nalbant P, Mikio Hoshino, and Bokoch GM. Signaling requirements for P-Rex1 translocation, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function. Journal of Leukocyte Biology 2007;81(4):1127-36.

Dehmelt L, Nalbant P, Steffen W, Halpain S. A microtubule-based, dynein-dependent force induces local cell protrusions: Implications for neurite initiation. Brain Cell Biology 2006;35(1):39-56. Epub 2007 Mar 13.

Belvindrah R, Nalbant P, Ding S, Wu C, Bokoch GM, Mueller U. Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development. Molecular and Cellular Neuroscience 2006;33(2):109-25.

Hodgson L, Nalbant P, Shen F, Hahn K. Imaging and Photobleach Correction of Mero-CBD, Sensor of Endogenous Cdc42 Activation. Methods in Enzymology 2006;406:140-56.

Subauste MC, Nalbant P, Adamson ED, Hahn KM. Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein beta-catenin with the scaffolding protein MAGI-2. Journal of Biological Chemistry 2005;280(7):5676-81.

Nalbant P, Hodgson L, Kraynov V, Toutchkine A, Hahn KM. Activation dynamics of endogenous Cdc42 visualized in living cells. Science 2004;305:1615-1619.

Tan X, Nalbant P, Toutchkine A, Hu D, Vorpagel ER, Hahn KM, and Lu PH. Single-Molecule Study of Protein-Protein Interaction Dynamics in a Cell Signaling System.Journal of Physical Chemistry B 2004; 108:737-44.

Tu SS, Wu WJ, Yang W, Nalbant P, Hahn K, Cerione RA. Antiapoptotic Cdc42 mutants are potent activators of cellular transformation. Biochemistry 2002;41(41):12350-8.


Molekulare Zellbiologie

ZMB/Faculty of Biology
University of Duisburg-Essen
45117 Essen

Room S05 V05 E26