ZMB Member Sven Rahmann

ZMB Member
Sven Rahmann

Next ZMB-Member
portrait photo of ZMB member Sven Rahmann
© UDE/S.Barcikowski

Prof. Dr. Sven Rahmann

Group

Genome Informatics

Faculty of Medicine
University Hospital Essen
Hufelandstr. 55
45147 Essen

Research Overview

  • Alignment-free sequence analysis
  • Resource-efficient bioinformatics algorithms
  • Sequence analysis applications in oncology and rare diseases
  • Statistical models in epigenomics
  • Pangenomics and applications
  • Modeling of protein hypernetworks
  • Quantification of diversity
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Selected Publications

    Journal articles

  • Wiesweg, Marcel; Mairinger, Fabian; Reis, Henning; Goetz, Moritz; Walter, Robert; Hager, Thomas; Metzenmacher, Martin; Eberhardt, Wilfried; McCutcheon, A.; Köster, J.; Stuschke, Martin; Aigner, Clemens; Darwiche, Kaid; Schmid, Kurt Werner; Rahmann, Sven; Schuler, Martin
    Machine learning-based predictors for immune checkpoint inhibitor therapy of non-small-cell lung cancer
    In: Annals of Oncology Vol. 30 (2019) Nr. 4, pp. 655 - 657
    ISSN: 1569-8041; 0923-7534
    Online Full Text: dx.doi.org/ (Open Access)
  • Ackermann, Sandra; Cartolano, Maria; Hero, Barbara; Welte, Anne; Kahlert, Yvonne; Roderwieser, Andrea; Bartenhagen, Christoph; Walter, Esther; Gecht, Judith; Kerschke, Laura; Volland, Ruth; Menon, Roopika; Heuckmann, Johannes M.; Gartlgruber, Moritz; Hartlieb, Sabine; Henrich, Kai-Oliver; Okonechnikov, Konstantin; Altmüller, Janine; Nürnberg, Peter; Lefever, Steve; De Wilde, Bram; Sand, Frederik; Ikram, Fakhera; Rosswog, Carolina; Fischer, Janina; Theissen, Jessica; Hertwig, Falk; Singhi, Aatur D.; Simon, Thorsten; Vogel, Wenzel; Perner, Sven; Krug, Barbara; Schmidt, Matthias; Rahmann, Sven; Achter, Viktor; Lang, Ulrich; Vokuhl, Christian; Ortmann, Monika; Büttner, Reinhard; Eggert, Angelika; Speleman, Frank; O’Sullivan, Roderick J.; Thomas, Roman K.; Berthold, Frank; Vandesompele, Jo; Schramm, Alexander; Westermann, Frank; Schulte, Johannes; Peifer, Martin; Fischer, Matthias
    A mechanistic classification of clinical phenotypes in neuroblastoma
    In: Science Vol. 362 (2018) Nr. 6419, pp. 1165 - 1170
    ISSN: 1095-9203; 0036-8075
    Online Full Text: dx.doi.org/
  • Marschall, Tobias; Marz, Manja; Abeel, Thomas; Dijkstra, Louis; Dutilh, Bas E.; Ghaffaari, Ali; Kersey, Paul; Kloosterman, Wigard P.; Mäkinen, Veli; Novak, Adam M.; Paten, Benedict; Porubsky, David; Rivals, Eric; Alkan, Can; Baaijens, Jasmijn A.; De Bakker, Paul I.W.; Boeva, Valentina; Bonnal, Raoul J.P.; Chiaromonte, Francesca; Chikhi, Rayan; Ciccarelli, Francesca D.; Cijvat, Robin; Datema, Erwin; Van Duijn, Cornelia M.; Eichler, Evan E.; Ernst, Corinna; Eskin, Eleazar; Garrison, Erik; El-Kebir, Mohammed; Klau, Gunnar W.; Korbel, Jan O.; Lameijer, Eric-Wubbo; Langmead, Benjamin; Martin, Marcel; Medvedev, Paul; Mu, John C.; Neerincx, Pieter; Ouwens, Klaasjan; Peterlongo, Pierre; Pisanti, Nadia; Rahmann, Sven; Raphael, Ben; Reinert, Knut; de Ridder, Dick; de Ridder, Jeroen; Schlesner, Matthias; Schulz-Trieglaff, Ole; Sanders, Ashley D.; Sheikhizadeh, Siavash; Shneider, Carl; Smit, Sandra; Valenzuela, Daniel; Wang, Jiayin; Wessels, Lodewyk; Zhang, Ying; Guryev, Victor; Vandin, Fabio; Ye, Kai; Schönhuth, Alexander
    Computational pan-genomics : Status, promises and challenges
    In: Briefings in Bioinformatics Vol. 19 (2018) Nr. 1, pp. 118 - 135
    ISSN: 1467-5463; 1477-4054
    Online Full Text: dx.doi.org/ (Open Access)
  • Stöcker, Bianca K; Köster, Johannes; Rahmann, Sven
    SimLoRD : Simulation of Long Read Data
    In: Bioinformatics Vol. 32 (2016) Nr. 17, pp. 2704 - 2706
    ISSN: 1367-4803; 1460-2059
    Online Full Text: dx.doi.org/ (Open Access)
  • Krüger, Anne; Oldenburg, Marina; Chebrolu, Chiranjeevi; Beisser, Daniela; Kolter, Julia; Sigmund, Anna M.; Steinmann, Jörg; Schäfer, Simon; Hochrein, Hubertus; Rahmann, Sven; Wagner, Hermann; Henneke, Philipp; Hornung, Veit; Buer, Jan; Kirschning, Carsten Jürgen
    Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
    In: EMBO Reports Vol. 16 (2015) Nr. 12, pp. 1656 - 1663
    ISSN: 1469-3178; 1469-221X
    Online Full Text: dx.doi.org/ (Open Access)
  • Schramm, Alexander; Köster, Johannes; Assenov, Yassen; Althoff, Kristina; Peifer, Martin; Mahlow, Ellen; Odersky, Andrea; Beisser, Daniela; Ernst, Corinna; Henssen, Anton G; Stephan, Harald; Schröder, Christopher; Heukamp, Lukas; Engesser, Anne; Kahlert, Yvonne; Theissen, Jessica; Hero, Barbara; Roels, Frederik; Altmüller, Janine; Nürnberg, Peter; Astrahantseff, Kathy; Gloeckner, Christian; De Preter, Katleen; Plass, Christoph; Lee, Sangkyun; Lode, Holger N; Henrich, Kai-Oliver; Gartlgruber, Moritz; Speleman, Frank; Schmezer, Peter; Westermann, Frank; Rahmann, Sven; Fischer, Matthias; Eggert, Angelika; Schulte, Johannes
    Mutational dynamics between primary and relapse neuroblastomas
    In: Nature Genetics Vol. 47 (2015) Nr. 8, pp. 872 - 877
    ISSN: 1061-4036; 1546-1718
    Online Full Text: dx.doi.org/
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Dörner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-?B signaling pathway
    In: Acta Neuropathologica Vol. 127 (2014) Nr. 4, pp. 609 - 611
    ISSN: 0001-6322; 1432-0533
    Online Full Text: dx.doi.org/
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Dörner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95–RELA fusions leading to pathological activation of the NF-κB signaling pathway
    In: Acta Neuropathologica Vol. 127 (2014) Nr. 4, pp. 609 - 611
    ISSN: 0001-6322; 1432-0533
    Online Full Text: dx.doi.org/
  • Martin, Marcel; Maßhöfer, Lars; Temming, Petra; Rahmann, Sven; Metz, Claudia; Bornfeld, Norbert; van de Nes, Johannes; Klein-Hitpaß, Ludger; Hinnebusch, Alan G.; Horsthemke, Bernhard; Lohmann, Dietmar; Zeschnigk, Michael
    Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
    In: Nature Genetics Vol. 45 (2013) Nr. 8, pp. 933 - 936
    ISSN: 1061-4036; 1546-1718
    Online Full Text: dx.doi.org/
  • Köster, Johannes; Rahmann, Sven
    Snakemake-a scalable bioinformatics workflow engine
    In: Bioinformatics Vol. 28 (2012) Nr. 19, pp. 2520 - 2522
    ISSN: 1460-2059; 1367-4803; 1367-4811
    Online Full Text: dx.doi.org/
  • Schulte, Johannes; Marschall, Tobias; Martin, Marcel; Rosenstiel, Philipp; Mestdagh, Pieter; Schlierf, Stefanie; Thor, Theresa; Vandesompele, Jo; Eggert, Angelika; Schreiber, Stefan; Rahmann, Sven; Schramm, Alexander
    Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
    In: Nucleic Acids Research Vol. 38 (2010) Nr. 17, pp. 5919 - 5928
    ISSN: 1362-4962; 0301-5610; 0305-1048
    Online Full Text: dx.doi.org/