Faculty of Biology
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Fakultät Biologie, ZMB, Mikrobiologie II, AG Ehrmann
Address
Universitätsstr. 2
45141 Essen
45141 Essen
Room
S03 S02 A64
Phone
Fax
E-Mail
Functions
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Wissenschaftliche/r Mitarbeiter/in, Mikrobiologie II
Current lectures
No current lectures.
Past lectures (max. 10)
No past lectures.
The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.
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A mouse model of cardiac immunoglobulin light chain amyloidosis reveals insights into tissue accumulation and toxicity of amyloid fibrilsIn: Nature Communications, Vol. 16, 2025, Nr. 1, 2992DOI (Open Access)
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The serine protease HTRA1 targets tau fibrils and provides a proteolytic barrier against pathogenic protein conformationsIn: The Journal of Biological Chemistry (JBC), Vol. 301, 2025, Nr. 10, 110729DOI, Online Full Text (Open Access)
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Rational correction of pathogenic conformational defects in HTRA1In: Nature Communications, Vol. 15, 2024, Nr. 1, 5944DOI (Open Access)
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Activation by substoichiometric inhibitionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 117, 2020, Nr. 3, pp. 1414 – 1418DOI, Online Full Text (Open Access)
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Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactionsIn: Nature Communications, Vol. 8, 2017, pp. 14472DOI, Online Full Text (Open Access)
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Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticlesIn: Beilstein Journal of Nanotechnology, Vol. 8, 2017, Nr. 1, pp. 381 – 393DOI, Online Full Text (Open Access)
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Substrate occupancy at the onset of oligomeric transitions of DegPIn: Structure, Vol. 22, 2014, Nr. 2, pp. 281 – 290DOI (Open Access)
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Diversity of allosteric regulation in proteasesIn: ACS Chemical Biology, Vol. 8, 2013, Nr. 1, pp. 19 – 26
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Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatisIn: Molecular Microbiology, Vol. 89, 2013, Nr. 4, pp. 676 – 689
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Protein quality control in the bacterial periplasmIn: Annual Review of Microbiology, Vol. 65, 2011, pp. 149 – 168
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Determinants of structural and functional plasticity of a widely conserved protease chaperone complexIn: Nature Structural & Molecular Biology, Vol. 17, 2010, Nr. 7, pp. 837 – 843
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Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coliIn: Research in Microbiology, Vol. 160, 2009, Nr. 9, pp. 660 – 666
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Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality controlIn: Angewandte Chemie International Edition, Vol. 47, 2008, Nr. 7, pp. 1332 – 1334
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Determinants of regulated proteolysis in signal transductionIn: Genes and Development, Vol. 21, 2007, Nr. 1, pp. 6 – 10
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A non-autonomous protein quality control mechanism targeting tau aggregate propagation2024DOI (Open Access)