Faculty of Biology
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Biologie / ZMB / Bioinformatics & Computational Biophysics
Address
Universitätsstr. 2-5
45141 Essen
45141 Essen
Room
S03 S03 A26
Phone
Fax
E-Mail
Functions
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
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Professor/in, Bioinformatik and Computational Biophysics
Current lectures
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2024 SS
Past lectures (max. 10)
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2023 WS
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2023 SS
The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.
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Increasing information gain in animal research by improving statistical model accuracyIn: Journal of Physics: Conference Series (JPCONF) Vol. 2514 (2023) Nr. 1, 012021Online Full Text: dx.doi.org/ (Open Access)
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Sequence diversity of hepatitis D virus in MongoliaIn: Frontiers in Medicine Vol. 10 (2023) 1108543Online Full Text: dx.doi.org/ (Open Access)
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio Vol. 14 (2023) Nr. 6, e02357-23Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinomaIn: Journal for ImmunoTherapy of Cancer Vol. 10 (2022) Nr. 1, e003198Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groupsIn: Beilstein Journal of Organic Chemistry Vol. 18 (2022) pp. 1322 - 1331Online Full Text: dx.doi.org/ (Open Access)
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DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinomaIn: Oncogene Vol. 41 (2022) Nr. 1, pp. 37 - 45Online Full Text: dx.doi.org/ (Open Access)
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Dissecting drivers of immune activation in chronic HIV-1 infectionIn: EBioMedicine Vol. 83 (2022) 104182Online Full Text: dx.doi.org/ (Open Access)
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances Vol. 12 (2022) Nr. 53, pp. 34176 - 34184Online Full Text: dx.doi.org/ (Open Access)
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HAMdetector : A Bayesian regression model that integrates information to detect HLA-associated mutationsIn: Bioinformatics Vol. 38 (2022) Nr. 9, pp. 2428 - 2436Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
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Immune escape pathways from the HBV core₁₈₋₂₇ CD8 T cell response are driven by individual HLA class I allelesIn: Frontiers in Immunology Vol. 13 (2022) 1045498Online Full Text: dx.doi.org/ (Open Access)
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A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19In: Frontiers in Cellular and Infection Microbiology Vol. 11 (2021) 747816Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytesIn: Cancer Immunology, Immunotherapy Vol. 70 (2021) Nr. 6, pp. 1635 - 1647Online Full Text: dx.doi.org/ (Open Access)
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Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal TransitionIn: Journal of Investigative Dermatology Vol. 141 (2021) Nr. 7, pp. 1675 - 1686.e4Online Full Text: dx.doi.org/ (Open Access)
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Classifier uncertainty : Evidence, potential impact, and probabilistic treatmentIn: PeerJ Computer Science Vol. 7 (2021) pp. e398Online Full Text: dx.doi.org/ (Open Access)
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Comprehensive Comparison of RNA-Seq Data of SARS-CoV-2, SARS-CoV and MERS-CoV Infections : Alternative Entry Routes and Innate Immune ResponsesIn: Frontiers in Immunology Vol. 12 (2021) 656433Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Epigenetic mechanisms mediating cell state transitions in chondrocytesIn: Journal of Bone and Mineral Research (JBMR) Vol. 36 (2021) Nr. 5, pp. 968 - 985Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axisIn: Cell Death and Disease Vol. 12 (2021) Nr. 1, 34Online Full Text: dx.doi.org/ (Open Access)
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Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamicsIn: The Journal of Immunology (JI) Vol. 206 (2021) Nr. 12, pp. 2839 - 2851Online Full Text: dx.doi.org/ (Open Access)
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Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic CellsIn: Frontiers in Immunology Vol. 11 (2021) pp. 607889Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdownIn: iScience Vol. 24 (2021) Nr. 11, 103366Online Full Text: dx.doi.org/ (Open Access)
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Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2In: BMC Public Health Vol. 21 (2021) Nr. 1, 1178Online Full Text: dx.doi.org/ (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Vol. 12 (2021) Nr. 1, pp. 1505Online Full Text: dx.doi.org/ (Open Access)
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UMI or not UMI, that is the question for scRNA-seq zero-inflationIn: Nature Biotechnology Vol. 39 (2021) Nr. 2, pp. 158 - 159Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719Online Full Text: dx.doi.org/ (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719Online Full Text: dx.doi.org/ (Open Access)
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An altered heparan sulfate structure in the articular cartilage protects against osteoarthritisIn: Osteoarthritis and Cartilage Vol. 28 (2020) Nr. 7, pp. 977 - 987Online Full Text: dx.doi.org/ (Open Access)
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Bayesian Data Integration Questions Classic Study on Protease Self-Digest KineticsIn: ACS Omega Vol. 5 (2020) Nr. 25, pp. 15162 - 15168Online Full Text: dx.doi.org/ (Open Access)
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Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfateIn: Matrix Biology Vol. 39 (2020) pp. 43 - 59Online Full Text: dx.doi.org/ (Open Access)
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Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19In: Frontiers in Immunology Vol. 11 (2020)Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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IgGeneUsage : differential gene usage in immune repertoiresIn: Bioinformatics Vol. 36 (2020) Nr. 11, pp. 3590 - 3591Online Full Text: dx.doi.org/
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Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell CarcinomaIn: Clinical Cancer Research Vol. 26 (2020) Nr. 9, pp. 2257 - 2267Online Full Text: dx.doi.org/ (Open Access)
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Rapid uptake of pre-exposure prophylaxis (PrEP) after significant price reduction in Germany highlights importance of PrEP accessibilityIn: AIDS Research and Human Retroviruses (2020)Online Full Text: dx.doi.org/
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Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophyIn: Developmental Biology Vol. 457 (2020) Nr. 1, pp. 104 - 118Online Full Text: dx.doi.org/ (Open Access)
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intePareto : an R package for integrative analyses of RNA-Seq and ChIP-Seq data
International Conference on Intelligent Biology and Medicine (ICIBM 2020), 9.-10.08.2020, Virtual,In: BMC Genomics Vol. 21 (2020) Nr. Supplement 11, pp. 802Online Full Text: dx.doi.org/ (Open Access) -
A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism Vol. 1 (2019) Nr. 2, pp. 236 - 250Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitudeIn: Chemical Communications: ChemComm Vol. 55 (2019) Nr. 1, pp. 111 - 114Online Full Text: dx.doi.org/
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Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bonesIn: PLoS ONE Vol. 14 (2019) Nr. 8, pp. e0218230
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Differential escape of HCV from CD8⁺ T cell selection pressure between China and Germany depends on the presenting HLA class I moleculeIn: Journal of Viral Hepatitis Vol. 26 (2019) Nr. 1, pp. 73 - 82Online Full Text: dx.doi.org/ (Open Access)
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Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases (JID) Vol. 219 (2019) Nr. 3, pp. 497 - 508Online Full Text: dx.doi.org/ (Open Access)
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Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population LevelIn: Gastroenterology Vol. 156 (2019) Nr. 6, pp. 1820 - 1833Online Full Text: dx.doi.org/ (Open Access)
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Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly : Recent Advances and PerspectivesIn: ACS Infectious Diseases Vol. 5 (2019) Nr. 5, pp. 713 - 724Online Full Text: dx.doi.org/
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Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDVIn: Journal of Hepatology Vol. 70 (2019) Nr. Suppl. 1, pp. e21Online Full Text: dx.doi.org/
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Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cellsIn: Journal of Virology Vol. 92 (2018) Nr. 13, pp. e01891 - 17Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood Vol. 131 (2018) Nr. 5, pp. 546 - 557Online Full Text: dx.doi.org/ (Open Access)
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Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodiesIn: Archives of Virology Vol. 163 (2018) Nr. 12, pp. 3303 - 3315Online Full Text: dx.doi.org/
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Illumina sequencing for the identification of filamentous bulking and foaming bacteria in industrial activated sludge plantsIn: International Journal of Environmental Science and Technology (IJEST) Vol. 15 (2018) Nr. 6, pp. 1139 - 1158Online Full Text: dx.doi.org/
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Locating Large, Flexible Ligands on ProteinsIn: Journal of Chemical Information and Modeling Vol. 58 (2018) Nr. 2, pp. 315 - 327Online Full Text: dx.doi.org/ (Open Access)
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Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wingIn: eLife Vol. 7 (2018) pp. e33033Online Full Text: dx.doi.org/ (Open Access)
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Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter ProteinIn: ChemBioChem Vol. 19 (2018) Nr. 6, pp. 591 - 595Online Full Text: dx.doi.org/
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Signaling systems affecting the severity of multiple osteochondromasIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Vol. 111 (2018) pp. 71 - 81Online Full Text: dx.doi.org/ (Open Access)
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Trade-off shapes diversity in eco-evolutionary dynamicsIn: eLife Vol. 7 (2018) pp. e36273Online Full Text: dx.doi.org/ (Open Access)
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Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated releaseIn: Journal of Cell Science Vol. 130 (2017) Nr. 19, pp. 3261 - 3271Online Full Text: dx.doi.org/ (Open Access)
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Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infectionIn: Retrovirology Vol. 14 (2017) 42Online Full Text: dx.doi.org/ (Open Access)
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Quantitative Assessment of Molecular Dynamics Sampling for Flexible SystemsIn: Journal of Chemical Theory and Computation Vol. 13 (2017) Nr. 2, pp. 400 - 414Online Full Text: dx.doi.org/
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Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology Vol. 13 (2017) Nr. 1, e1005362Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Role of Gag mutations in PI resistance in the Swiss HIV cohort study : bystanders or contributors?In: Journal of Antimicrobial Chemotherapy Vol. 72 (2017) Nr. 3, pp. 866 - 875Online Full Text: dx.doi.org/ (Open Access)
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Protistan community analysis : key findings of a large scale molecular samplingIn: ISME Journal Vol. 10 (2016) pp. 2269 - 2279Online Full Text: dx.doi.org/ (Open Access)
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SeqFeatR for the Discovery of Feature-Sequence AssociationsIn: PLoS ONE Vol. 11 (2016) Nr. 1, pp. e0146409Online Full Text: dx.doi.org/ (Open Access)
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Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection PressureIn: Hepatology Vol. 62 (2015) Nr. 1, pp. 47 - 56Online Full Text: dx.doi.org/ (Open Access)
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AmpliconDuo : a split-sample filtering protocol for high-throughput amplicon sequencing of microbial communitiesIn: PLoS ONE Vol. 10 (2015) Nr. 11, pp. e0141590Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centersIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 112 (2015) Nr. 38, pp. E5281 - E5289Online Full Text: dx.doi.org/ (Open Access)
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Parameters influencing baseline HIV-1 genotypic tropism testing related to clinical outcome in patients on maravirocIn: PLoS ONE Vol. 10 (2015) Nr. 5, pp. e0125502Online Full Text: dx.doi.org/ (Open Access)
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Pareto optimization identifies diverse set of phosphorylation signatures predicting response to treatment with dasatinibIn: PLoS ONE Vol. 10 (2015) Nr. 6, pp. e0128542Online Full Text: dx.doi.org/ (Open Access)
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Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry Vol. 36 (2015) Nr. 6, pp. 2379 - 2392Online Full Text: dx.doi.org/ (Open Access)
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A simple structure-based model for the prediction of HIV-1 co-receptor tropismIn: BioData Mining Vol. 7 (2014) pp. 14Online Full Text: dx.doi.org/ (Open Access)
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Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'In: Virologica Sinica Vol. 29 (2014) Nr. 1, pp. 40 - 47Online Full Text: dx.doi.org/
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HLA-B*27 is protective against HCV genotype 1 and 3 and associated with targeting of distinct genotype-specific CD8(+) cell epitopesIn: Journal of Hepatology Vol. 60 (2014) Nr. Suppl. 1, pp. 140Online Full Text: dx.doi.org/
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Identification of Significant Features by the Global Mean Rank TestIn: PLoS ONE Vol. 9 (2014) Nr. 8, pp. e104504Online Full Text: dx.doi.org/ (Open Access)
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Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-PeptidaseIn: PLoS Computational Biology Vol. 10 (2014) Nr. 7, pp. e1003707Online Full Text: dx.doi.org/ (Open Access)
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A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 GenomesIn: PLoS ONE Vol. 8 (2013) Nr. 3, pp. e58804Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of armsIn: Organic and Biomolecular Chemistry Vol. 11 (2013) Nr. 10, pp. 1631 - 1639Online Full Text: dx.doi.org/
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Correction: A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 Genomes.In: PLoS ONE Vol. 8 (2013) Nr. 12,Online Full Text: dx.doi.org/ (Open Access)
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Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE Vol. 8 (2013) Nr. 6, pp. e65346Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Inference of global HIV-1 sequence patterns and preliminary feature analysisIn: Virologica Sinica Vol. 28 (2013) Nr. 4, pp. 228 - 238Online Full Text: dx.doi.org/
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Novel Algorithm for Non-Invasive Assessment of Fibrosis in NAFLDIn: PLoS ONE Vol. 8 (2013) Nr. 4, pp. e62439Online Full Text: dx.doi.org/ (Open Access)
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The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovirIn: Antiviral Research Vol. 97 (2013) Nr. 2, pp. 93 - 100Online Full Text: dx.doi.org/
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Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Vol. 21 (2013) Nr. 10, pp. 1769 - 1777Online Full Text: dx.doi.org/ (Open Access)
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An emerging role of sonic hedgehog shedding as a modulator of heparan sulfate interactionsIn: The Journal of Biological Chemistry (JBC) Vol. 287 (2012) Nr. 52, pp. 43708 - 43719Online Full Text: dx.doi.org/
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Escape from a dominant hla-b*15-restricted cd8+ t cell response against hepatitis c virus requires compensatory mutations outside the epitopeIn: Journal of Virology Vol. 86 (2012) Nr. 2, pp. 991 - 1000Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The Normal-Mode Entropy in the MM/GBSA Method : Effect of System Truncation, Buffer Region, and Dielectric ConstantIn: Journal of Chemical Information and Modeling Vol. 52 (2012) Nr. 8, pp. 2079 - 2088Online Full Text: dx.doi.org/ (Open Access)
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The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated proteinIn: Human Molecular Genetics Vol. 21 (2012) Nr. 18, pp. 4038 - 4048Online Full Text: dx.doi.org/ (Open Access)
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An additional glucose dehydrogenase from Sulfolobus solfataricus : fine-tuning of sugar degradation?In: Biochemical Society Transactions Vol. 39 (2011) Nr. 1, pp. 77 - 81Online Full Text: dx.doi.org/
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Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptidesIn: Nature Communications Vol. 2 (2011) pp. 453Online Full Text: dx.doi.org/ (Open Access)
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CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural ProteinsIn: Gastroenterology Vol. 140 (2011) Nr. 7, pp. 2064 - 2073Online Full Text: dx.doi.org/
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Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiersIn: BioData Mining Vol. 4 (2011) Nr. 1, pp. 26Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Interpol : An R package for preprocessing of protein sequencesIn: BioData Mining Vol. 4 (2011) pp. 16Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Machine learning on normalized protein sequencesIn: BMC Research Notes Vol. 4 (2011) pp. 94Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Parental origin and functional relevance of a de novo UBE3A variantIn: European Journal of Medical Genetics (EJMG) Vol. 54 (2011) Nr. 1, pp. 19 - 24Online Full Text: dx.doi.org/
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Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Vol. 7 (2011) pp. 135 - 148Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Sonic hedgehog shedding results in functional activation of the solubilized proteinIn: Developmental Cell Vol. 20 (2011) Nr. 6, pp. 764 - 774Online Full Text: dx.doi.org/ (Open Access)
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Estimating affinities of calcium ions to proteinsIn: Advances and Applications in Bioinformatics and Chemistry Vol. 3 (2010) Nr. 1, pp. 1 - 6Online Full Text: dx.doi.org/ (Open Access)
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Predicting Bevirimat resistance of HIV-1 from genotypeIn: BMC Bioinformatics Vol. 11 (2010) pp. 37Online Full Text: dx.doi.org/ (Open Access)
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Prediction of Co-Receptor Usage of HIV-1 from GenotypeIn: PLoS Computational Biology Vol. 6 (2010) Nr. 4, pp. e1000743Online Full Text: dx.doi.org/ (Open Access)
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Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrateIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 107 (2010) Nr. 12, pp. 5522 - 5527Online Full Text: dx.doi.org/
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Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism.In: AIDS Research and Therapy Vol. 7 (2010) pp. 41Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitroIn: Antiviral Research Vol. 86 (2010) Nr. 3, pp. 312 - 315Online Full Text: dx.doi.org/
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Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60In: Chromosoma Vol. 119 (2010) Nr. 1, pp. 99 - 113Online Full Text: dx.doi.org/
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A novel algorithm for macromolecular epitope matchingIn: Algorithms Vol. 2 (2009) Nr. 1, pp. 498 - 517Online Full Text: dx.doi.org/
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Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patientsIn: Journal of Infection Vol. 58 (2009) Nr. 1, pp. 61 - 67Online Full Text: dx.doi.org/
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Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failureIn: Journal of Clinical Virology Vol. 45 (2009) Nr. 1, pp. 34 - 38Online Full Text: dx.doi.org/
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Biallelic loss of function of the promyelocytic leukaemia zinc finger (PLZF) gene causes severe skeletal defects and genital hypoplasiaIn: Journal of Medical Genetics (eJMG) Vol. 45 (2008) Nr. 11, pp. 731 - 737Online Full Text: dx.doi.org/
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Evolution : von der Biologie zur Mathematik und wieder zurück ; die Ergebnisse der Evolutionstheorie sind heute nicht nur Naturbeschreibung, sondern auch mathematisches WerkzeugIn: Unikate: Berichte aus Forschung und Lehre (2008) Nr. 33: Mathematik: eine lebendige Wissenschaft, pp. 54 - 65Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Evolutionary Pareto-optimization of stably folding peptidesIn: BMC Bioinformatics Vol. 9 (2008) pp. 109Online Full Text: dx.doi.org/ (Open Access)
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The B-cell epitope of the monoclonal anti-factor VIII anti- body ESH8 characterized by peptide array analysisIn: Thrombosis and Haemostasis Vol. 99 (2008) Nr. 3, pp. 634 - 637Online Full Text: dx.doi.org/
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A multiobjective evolutionary method for the design of peptidic mimotopesIn: Journal of Computational Biology Vol. 13 (2006) Nr. 1, pp. 113 - 125Online Full Text: dx.doi.org/
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Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.In: Antiviral Therapy Vol. 11 (2006) Nr. 7, pp. 879 - 887
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SearchXLinks : A program for the identification of disulfide bonds in proteins from mass spectraIn: Analytical Chemistry Vol. 78 (2006) Nr. 4, pp. 1235 - 1241Online Full Text: dx.doi.org/
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The enzyme-binding region of human GM2-activator proteinIn: The FEBS Journal Vol. 273 (2006) Nr. 5, pp. 982 - 991Online Full Text: dx.doi.org/
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Computational methods for the design of effective therapies against drug resistant HIV strainsIn: Bioinformatics Vol. 21 (2005) Nr. 21, pp. 3943 - 3950Online Full Text: dx.doi.org/ (Open Access)
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Estimating HIV evolutionary pathways and the genetic barrier to drug resistanceIn: Journal of Infectious Diseases Vol. 191 (2005) Nr. 11, pp. 1953 - 1960Online Full Text: dx.doi.org/ (Open Access)
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Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapyIn: Journal of Clinical Virology Vol. 34 (2005) Nr. 4, pp. 277 - 287Online Full Text: dx.doi.org/
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Learning multiple evolutionary pathways from cross-sectional dataIn: Journal of Computational Biology Vol. 12 (2005) Nr. 6, pp. 584 - 598Online Full Text: dx.doi.org/
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Mtreemix : A software package for learning and using mixture models of mutagenetic treesIn: Bioinformatics Vol. 21 (2005) Nr. 9, pp. 2106 - 2107Online Full Text: dx.doi.org/ (Open Access)
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Photoaffinity labelling of the Human GM2-activator protein Mechanistic insight into ganglioside GM2 degradationIn: European Journal of Biochemistry: the FEBS journal Vol. 271 (2004) Nr. 3, pp. 614 - 627Online Full Text: dx.doi.org/
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Geno2pheno : Estimating phenotypic drug resistance from HIV-1 genotypesIn: Nucleic Acids Research Vol. 31 (2003) Nr. 13, pp. 3850 - 3855Online Full Text: dx.doi.org/
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Methods for optimizing antiviral combination therapiesIn: Bioinformatics Vol. 19 (2003) Nr. Suppl 1, pp. i16 - i25Online Full Text: dx.doi.org/ (Open Access)
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Structural modeling of ataxin-3 reveals distant homology to adaptinsIn: Proteins: Structure, Function and Genetics Vol. 50 (2003) Nr. 2, pp. 355 - 370Online Full Text: dx.doi.org/
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Tenofovir Resistance and ResensitizationIn: Antimicrobial Agents and Chemotherapy Vol. 47 (2003) Nr. 11, pp. 3478 - 3484Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotypeIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 99 (2002) Nr. 12, pp. 8271 - 8276Online Full Text: dx.doi.org/
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Partial reduction and two-step modification of proteins for identification of disulfide bondsIn: Analytical Chemistry Vol. 74 (2002) Nr. 10, pp. 2386 - 2393Online Full Text: dx.doi.org/
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Screening for disulfide bonds in proteins by MALDI in-source decay and LIFT-TOF/TOF-MSIn: Analytical Chemistry Vol. 74 (2002) Nr. 19, pp. 4980 - 4988Online Full Text: dx.doi.org/
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Web Site : The Protein Information ResourceIn: Angewandte Chemie International Edition Vol. 41 (2002) Nr. 6, pp. 1075 - 1075Online Full Text: dx.doi.org/
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Geno2pheno : Interpreting Genotypic HIV Drug Resistance TestsIn: IEEE Intelligent Systems Vol. 16 (2001) Nr. 6, pp. 35 - 41Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Neue Wege zur Optimierung von Anti-HIV-Therapien : Erste Analysen mit bioinformatischen MethodenIn: BIOforum Vol. 24 (2001) Nr. 12, pp. 912 - 914
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Band-flip and kink as novel structural motifs in α-(1→4)-D-glucose oligosaccharides. Crystal structures of cyclodeca- and cyclotetradecaamyloseIn: Carbohydrate Research Vol. 322 (1999) Nr. 3-4, pp. 228 - 246Online Full Text: dx.doi.org/
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Two-Stage Method for Protein-Ligand DockinIn: (J. Med. Chem.) Vol. 42 (1999) pp. 4422 - 4433
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Two-stage method for protein-ligand dockingIn: Journal of Medicinal Chemistry Vol. 42 (1999) Nr. 21, pp. 4422 - 4433Online Full Text: dx.doi.org/
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A structural role for glycosylation : Lessons from the hp modelIn: Folding and Design Vol. 3 (1998) Nr. 5, pp. 337 - 343Online Full Text: dx.doi.org/ (Open Access)
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A structural role for glycosylation: lessons from the hp-modeIn: Folding & Design Vol. 3 (1998) pp. 337 - 343
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Strain-Induced “Band Flips” in Cyclodecaamylose and Higher HomologuesIn: Angewandte Chemie International Edition Vol. 37 (1998) Nr. 5,Online Full Text: dx.doi.org/
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Structures of the Common Cyclodextrins and Their Larger Analogues -- Beyond the DoughnuIn: Chemical Reviews Vol. 98 (1998) pp. 1787 - 1802
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Structures of the common cyclodextrins and their larger analogues : beyond the doughnutIn: Chemical Reviews Vol. 98 (1998) Nr. 5, pp. 1787 - 1802Online Full Text: dx.doi.org/
-
Folding Pathways of a Helix-Turn-Helix Model ProteinIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 101 (1997) Nr. 34, pp. 6734 - 6740Online Full Text: dx.doi.org/ (Open Access)
-
Polypeptide folding with-off lattice Monte Carlo dynamics : The methodIn: European Biophysics Journal Vol. 24 (1996) Nr. 6, pp. 387 - 403Online Full Text: dx.doi.org/
-
Protein dynamics with off-lattice monte carlo movesIn: Physical Review E: Statistical, nonlinear, and soft matter physics Vol. 53 (1996) Nr. 4, pp. 4221 - 4224Online Full Text: dx.doi.org/ (Open Access)
-
Ensuring fuels for DNA repair : Analysis of irradiated cancer cells reveals mitochondrial shutdownIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Vol. 197 (2021) Nr. Suppl. 1, pp. 200
-
Epigenetic profiling of articular chondrocytes
OARSI World Congress on Osteoarthritis, 29.04.-01.05.2021, Virtual,In: Osteoarthritis and Cartilage Vol. 29 (2021) Nr. Suppl. 1: Abstracts from the Virtual 2021 OARSI World Congress on Osteoarthritis, pp. 309Online Full Text: dx.doi.org/ (Open Access) -
Modeling common aspects of the metabolic response of cancer cells to ionizing radiationIn: Cancer Research Vol. 81 (2021) Nr. 13, 3065
-
A phase 3b, open-label, pilot study to evaluate switching to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) in virologically-suppressed HIV-1 infected adult subjects harboring the NRTI resistance mutation M184V and/or M184I (GS-US-292-1824)In: Journal of the International AIDS Society Vol. 21 (2018) Nr. Suppl. 6, e25148Online Full Text: dx.doi.org/ (Open Access)
-
Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B CellsIn: Scandinavian Journal of Immunology Vol. 80 (2014) Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, pp. 233Online Full Text: dx.doi.org/
-
Optimisation of baseline genotypic testing for safe and efficient maraviroc administrationIn: Journal of the International AIDS Society Vol. 15 (2012) Nr. S4, pp. P165Online Full Text: dx.doi.org/ (Open Access)
-
Predicting HIV-1 Cytopathogenicity and Co-Receptor Usage from V3 Envelope Sequences by Machine LearningIn: The 1st IAS Conference on HIV Pathogenesis and Treatment, July 8-11, 2001, Buenos Aires, Argentina: science leading the future : final programme and abstracts / 1st IAS Conference on HIV Pathogenesis and Treatment, 8-11 July 2001, Buenos Aires, Argentina (2001) pp. 268
-
Arevir : A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIVIn: Data Integration in the Life Sciences / Third International Workshop (DILS), July 20-22, 2006, Hinxton, UK, / Leser, Ulf; Naumann, Felix; Eckman, Barbara (Eds.) 2006, pp. 185 - 194Online Full Text: dx.doi.org/
-
A multi-objective evolutionary approach to peptide structure redesign and stabilizationIn: Proceedings of the 7th annual conference on Genetic and evolutionary computation / GECCO 2005 - Genetic and Evolutionary Computation Conference, 25-29 June 2005, Washington D.C., United States / Beyer, Hans-Georg (Eds.) 2005, pp. 423 - 429Online Full Text: dx.doi.org/
-
Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature RankingIn: Knowledge Discovery in Databases: PKDD 2005: th European Conference on Principles and Practice of Knowledge Discovery in Databases, Porto, Portugal, October 3-7, 2005. Proceedings / 9th European Conference on Principles and Practice of Knowledge Discovery in Databases (PKDD 2005), 3-7 October 2005, Porto, Portugal / Jorge, Alípio Mário; Torgo, Luís; Brazdil, Pavel; Camacho, Rui; Gama, João (Eds.) 2005, pp. 285 - 296Online Full Text: dx.doi.org/
-
Computergestützte molekulare Modellierung für die Suche nach neuen Wirkstoffen gegen HIV/AIDSIn: Resistenz in der HIV-Therapie: Diagnostik und Management / Oette, Mark; Kaiser, Rolf; Häussinger, Dieter (Eds.) 2003, pp. 62 - 65
-
A New Method for the Fast Solution of Protein-3D-Structures, combining Experiments and BioinformaticsIn: Coupling of Biological and Electronic Systems: Proceedings of the 2nd Caesarium / 2nd Caesarium, Bonn, November 1–3, 2000 / Hoffmann, Karl-Heinz (Eds.) 2002, pp. 59 - 78Online Full Text: dx.doi.org/
-
Identifying Drug Resistance-Associated Patterns in HIV GenotypesIn: Computer science and biology: proceedings of the German Conference on Bioinformatics / German Conference on Bioinformatics (GCB '01), 7.-10. October 2001, Braunschweig / Wingender, Edgar (Eds.) 2001, pp. 126 - 130
-
Simulation of oligopeptide folding or how do residues talkIn: Biological Physics: Third International Symposium ; Santa Fe, NM, September 1998 / Third International Symposium on Biological Physics ; September 20-24, 1998, Santa Fe, New Mexico, USA / Frauenfelder, Hans; Hummer, Gerhard; Garcia, Roderick (Eds.) 1999, pp. 54 - 68Online Full Text: dx.doi.org/
-
Tackling Concrete Problems in Molecular Biophysics Using Monte Carlo and Related Methods : Glycosylation, Folding, SolvationIn: Workshop on Monte Carlo Approach to Biopolymers and Protein Folding / Workshop on Monte Carlo Approach to Biopolymers and Protein, 3 - 5 December 1997 , Jülich, Germany / Grassberger, P.; Barkema, G.; Nadler, W. (Eds.) 1998, pp. 153 - 170
-
A Monte Carlo method for simulations of protein folding with detailed protein modelsIn: Perspectives on protein engineering: a comprehensive on-line access tool for Web-based resources, papers from Perspectives on Protein Engineering '96 / Perspectives on Protein Engineering Conference 5 (POPE5), 2-6 March 1996, Montpellier 1996
-
Monte Carlo Methoden zur Simulation der Langzeitdynamik von ProteinenBerlin (1996) 115 Seiten (Bioinformatik)