Faculty of Biology
Register of People
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Fakultät für Biologie - Molekulare Zellbiologie
Address
Universitätsstraße 5
45141 Essen
45141 Essen
Room
T03 R01 D33
Phone
Fax
E-Mail
Functions
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Universitätsprofessor/in, Molekulare Zellbiologie
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
Current lectures
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2024 SS
- Applied Molecular Biology
- (Einführung in die) Molekularbiologie
- (Einführung in die) Molekularbiologie (LA Ba und Bio B.Sc.); Einführung in die molekulare Zellbiologie (MolBio Bachelor)
- Übung Molekulare Zellbiologie für Molekularbiologen
- Praktikum Chemie für Lehramtsstudierende
- Methods in Cancer Research
- Zell- und Molekularbiologie
Past lectures (max. 10)
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2023 WS
- Einführung in die Molekularbiologie (für Molekularbiologen - BA 1. Sem)
- Übung zur Einführung in die Molekularbiologie
- Zell- und Molekularbiologie
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Molecular Cell Biology
- Allgemeine Methoden (Bachelor Bio)
- Allgemeine Methoden in der Molekularbiologie
- Molekulare Zellbiologie
- TAC-Meeting
- Allgemeine Methoden Praktikum (Bachelor Bio); Priorität für G1 oder G2
The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.
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Cdc42 activity in the trailing edge is required for persistent directional migration of keratinocytesIn: Molecular Biology of the Cell Vol. 35 (2023) Nr. 1, br1Online Full Text: dx.doi.org/
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Direct investigation of cell contraction signal networks by light-based perturbation methodsIn: Pflügers Archiv: European Journal of Physiology Vol. 475 (2023) Nr. 12, pp. 1439 - 1452Online Full Text: dx.doi.org/
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Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cyclesIn: Nature Communications Vol. 14 (2023) Nr. 1, 8356Online Full Text: dx.doi.org/ (Open Access)
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Monitoring the Response of Multiple Signal Network Components to Acute Chemo-Optogenetic Perturbations in Living CellsIn: ChemBioChem Vol. 23 (2022) Nr. 4, e202100582Online Full Text: dx.doi.org/ (Open Access)
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The Taspase1/Myosin1f-axis regulates filopodia dynamicsIn: iScience Vol. 25 (2022) Nr. 6, 104355Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisIn: Cell Reports Vol. 37 (2021) Nr. 8, 110056Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal NetworkIn: Cell Reports Vol. 33 (2020) Nr. 9, pp. 108467Online Full Text: dx.doi.org/ (Open Access)
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Exploratory cell dynamics : A sense of touch for cells?In: Biological Chemistry Vol. 399 (2018) Nr. 8, pp. 809 - 819Online Full Text: dx.doi.org/ (Open Access)
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An excitable Rho GTPase signaling network generates dynamic subcellular contraction patternsIn: The Journal of Cell Biology (JCB) Vol. 216 (2017) Nr. 12, pp. 4271 - 4285Online Full Text: dx.doi.org/ (Open Access)
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Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 ExpressionIn: PLoS ONE Vol. 10 (2015) Nr. 9, pp. e0137043Online Full Text: dx.doi.org/ (Open Access)
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Everolimus Prevents Podocyte Injury Via Stabilizing Tubb2b And Dcdc2 ExpressionIn: Pediatric Nephrology Vol. 29 (2014) Nr. 9, pp. 1674 - 1674Online Full Text: dx.doi.org/
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FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibersIn: Journal of Cell Science Vol. 127 (2014) Nr. 7, pp. 1379 - 1393Online Full Text: dx.doi.org/ (Open Access)
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Differential expression of cytoskeletal-associated genes in human podocytes by the mTOR inhibitor everolimusIn: Pediatric Nephrology Vol. 28 (2013) Nr. 8, pp. 1438 - 1438
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Protective effects of the mTOR inhibitor everolimus on cytoskeletal injury in human podocytes are mediated by RhoA signalingIn: PLoS ONE Vol. 8 (2013) Nr. 2, pp. e55980Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Calcium phosphate nanoparticles as versatile carrier for small and large molecules across cell membranesIn: Journal of Nanoparticle Research Vol. 14 (2012) Nr. 6, 0910Online Full Text: dx.doi.org/
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Protective effects of everolimus on puromycin-induced cytoskeletal alterations in human podocytes are mediated by RhoA-signallingIn: Pediatric Nephrology Vol. 27 (2012) Nr. 9, pp. 1638 - 1638
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Coordination of Rho GTPase activities during cell protrusionIn: Nature Vol. 461 (2009) Nr. 7260, pp. 99 - 103
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Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edgeIn: Molecular Biology of the Cell Vol. 20 (2009) Nr. 18, pp. 4070 - 4082
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RhoA GTPase activation by TLR2 and TLR3 ligands: Connecting via Src to NF-κBIn: The Journal of Immunology (JI) Vol. 182 (2009) Nr. 6, pp. 3522 - 3529Online Full Text: dx.doi.org/
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3GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoAIn: Molecular Biology of the Cell Vol. 19 (2008) Nr. 5, pp. 2147 - 2153
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Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?In: Trends in Cell Biology Vol. 18 (2008) Nr. 5, pp. 210 - 219
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Processing of naturally occurring sense/antisense transcripts of the vertebrate Slc34a gene into short RNAsIn: Physiological Genomics Vol. 34 (2008) Nr. 1, pp. 95 - 100
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PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motilityIn: The Journal of Cell Biology (JCB) Vol. 180 (2008) Nr. 1, pp. 187 - 203Online Full Text: dx.doi.org/
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Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cellsIn: Journal of Cell Science Vol. 120 (2007) Nr. 19, pp. 3465 - 3474
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GEF-H1 Modulates Localized RhoA Activation during Cytokinesis under the Control of Mitotic KinasesIn: Developmental Cell Vol. 12 (2007) Nr. 5, pp. 699 - 712Online Full Text: dx.doi.org/ (Open Access)
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Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cellsIn: The Journal of Cell Biology (JCB) Vol. 179 (2007) Nr. 3, pp. 403 - 410
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Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil functionIn: Journal of Leukocyte Biology Vol. 81 (2007) Nr. 4, pp. 1127 - 1136
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Visualizing TLR2- and TLR3-dependent RhoA activation by fret biosensorIn: Journal of Leukocyte Biology (2007) Nr. Supplement, pp. 36 - 36
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A microtubule-based, dynein-dependent force induces local cell protrusions: Implications for neurite initiationIn: Brain Cell Biology Vol. 35 (2006) Nr. 1, pp. 39 - 56
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Imaging and photobleach correction of Mero-CBD, sensor of endogenous Cdc42 activationIn: Methods in Enzymology Vol. 406 (2006) Nr. 12, pp. 140 - 156
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Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar developmentIn: Molecular and Cellular Neuroscience (MCN) Vol. 33 (2006) Nr. 2, pp. 109 - 125
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Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein β-catenin with the scaffolding protein MAGI-2In: The Journal of Biological Chemistry (JBC) Vol. 280 (2005) Nr. 7, pp. 5676 - 5681
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Activation of endogenous Cdc42 visualized in living cellsIn: Science Vol. 305 (2004) Nr. 5690, pp. 1615 - 1619
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Single-Molecule Study of Protein-Protein Interaction Dynamics in a Cell Signaling SystemIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 108 (2004) Nr. 2, pp. 737 - 744
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Characterization of a type IIb sodium-phosphate cotransporter from zebrafish (Danio rerio) kidneyIn: American Journal of Physiology - Renal Physiology Vol. 284 (2003) Nr. 4, pp. F727 - F736
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Single-molecule protein-protein interaction dynamics of GTP-binding protein Cdc42 with downstream effector WASPIn: Biophysical Journal Vol. 84 (2003) Nr. Suppl 2 Pt 2, pp. 485a
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Facile synthesis of thiol-reactive Cy3 and Cy5 derivatives with enhanced water solubilityIn: Bioconjugate Chemistry Vol. 13 (2002) Nr. 3, pp. 387 - 391
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Regulation of the NPT gene by a naturally occurring antisense transcriptIn: Cell Biochemistry and Biophysics Vol. 36 (2002) Nr. 2/3, pp. 241 - 252
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Functional characterization of a Na+-phosphate cotransporter (NaP(i)-II) from zebrafish and identification of related transcriptsIn: Journal of Physiology Vol. 520 (1999) Nr. 1, pp. 79 - 89
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Na+-dependent phosphate cotransporters : The NaPi protein familiesIn: The Journal of Experimental Biology Vol. 201 (1998) Nr. 23, pp. 3135 - 3142
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Role of IFNγ-induced tumor-T cell equilibrium in melanoma latencyIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Vol. 21 (2023) Nr. S4, Special Issue: Abstractband anlässlich des 33. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 06.–09. September 2023 Hamburg, pp. 34Online Full Text: dx.doi.org/ (Open Access)
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Signale in wandernden Zellen : Direkte Beobachtungen durch Fluoreszenzmikroskope
Die kleine Form, 20. Mai 2009, Essen,(2009) (Die kleine Form 2009)