Faculty of Biology
Register of People
The person's links lead to the central register of persons of the UDE, refering to the data of LSF. Personal data can be edited in LSF (Login with Uni-ID is required).
Fakultät Biologie
Address
Universitätsstr. 5
45141 Essen
45141 Essen
Room
T03 R04 D04
Phone
Functions
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Wissenschaftliche/r Mitarbeiter/in, Molekularbiologie I
Current lectures
No current lectures.
Past lectures (max. 10)
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2013 SS
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2012 WS
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2012 SS
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2011 WS
The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.
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Lysosomal damage sensing and lysophagy initiation by SPG20-ITCHIn: Molecular Cell (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substratesIn: Nature Communications Vol. 15 (2024) Nr. 1, 2459Online Full Text: dx.doi.org/ (Open Access)
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Structural basis of ubiquitin-independent PP1 complex disassembly by p97In: The EMBO Journal Vol. 42 (2023) Nr. 14, e113110Online Full Text: dx.doi.org/ (Open Access)
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Targeting of client proteins to the VCP/p97/Cdc48 unfolding machineIn: Frontiers in Molecular Biosciences Vol. 10 (2023) 1142989Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseIn: Nature Communications Vol. 14 (2023) Nr. 1, 3258Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Ubiquitin-directed AAA+ ATPase p97/VCP unfolds stable proteins crosslinked to DNA for proteolysis by SPRTNIn: The Journal of Biological Chemistry (JBC) Vol. 298 (2022) Nr. 6, 101976Online Full Text: dx.doi.org/ (Open Access)
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Targeted substrate loop insertion by VCP/p97 during PP1 complex disassemblyIn: Nature Structural & Molecular Biology Vol. 28 (2021) Nr. 12, pp. 964 - 971Online Full Text: dx.doi.org/
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Protein Phosphatase-1 Complex Disassembly by p97 is Initiated through Multivalent Recognition of Catalytic and Regulatory Subunits by the p97 SEP-domain AdaptersIn: Journal of Molecular Biology (JMB) Vol. 432 (2020) Nr. 23, pp. 6061 - 6074Online Full Text: dx.doi.org/
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The chaperone Lhs1 contributes to the virulence of the fish-pathogenic oomycete Aphanomyces invadansIn: Fungal Biology Vol. 124 (2020) Nr. 12, pp. 1024 - 1031Online Full Text: dx.doi.org/
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The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent mannerIn: Nanoscale Vol. 12 (2020) Nr. 37, pp. 19093 - 19103Online Full Text: dx.doi.org/
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Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPaseIn: Biomolecules Vol. 9 (2019) Nr. 12, 876Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPasesIn: Angewandte Chemie International Edition Vol. 57 (2018) Nr. 6, pp. 1576 - 1580Online Full Text: dx.doi.org/
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Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1In: The Journal of Biological Chemistry (JBC) Vol. 293 (2018) Nr. 25, pp. 9724 - 9735Online Full Text: dx.doi.org/ (Open Access)
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Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme FormationIn: Molecular Cell Vol. 72 (2018) Nr. 4, pp. 766 - 777Online Full Text: dx.doi.org/ (Open Access)
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VCP/p97-Mediated Unfolding as a Principle in Protein Homeostasis and SignalingIn: Molecular Cell Vol. 69 (2018) Nr. 2, pp. 182 - 194Online Full Text: dx.doi.org/ (Open Access)
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Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1In: PLoS ONE Vol. 11 (2016) Nr. 3, pp. e0151431Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Taspase1 : a 'misunderstood' protease with translational cancer relevanceIn: Oncogene Vol. 35 (2016) Nr. 26, pp. 3351 - 3364Online Full Text: dx.doi.org/
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VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break RepairIn: Molecular Cell Vol. 64 (2016) Nr. 1, pp. 189 - 198Online Full Text: dx.doi.org/ (Open Access)
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Structural model of the bilitranslocase transmembrane domain supported by NMR and FRET dataIn: PLoS ONE Vol. 10 (2015) Nr. 8, pp. e0135455Online Full Text: dx.doi.org/ (Open Access)
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Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem Vol. 15 (2014) Nr. 15, pp. 2233 - 2237Online Full Text: dx.doi.org/
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Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Vol. 21 (2013) Nr. 10, pp. 1769 - 1777Online Full Text: dx.doi.org/ (Open Access)
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3'-Phosphoadenosine 5'-phosphosulfate (PAPS) synthases, naturally fragile enzymes specifically stabilized by nucleotide bindingIn: The Journal of Biological Chemistry (JBC) Vol. 2012 (2012) pp. 17645 - 17655Online Full Text: dx.doi.org/
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Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Vol. 7 (2011) pp. 135 - 148Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Sonic hedgehog shedding results in functional activation of the solubilized proteinIn: Developmental Cell Vol. 20 (2011) Nr. 6, pp. 764 - 774Online Full Text: dx.doi.org/ (Open Access)
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A Heterodimer of Human 3′-Phospho-Adenosine-5′-Phosphosulphate (PAPS) Synthases Is a New Sulphate Activating ComplexIn: Biochemical and Biophysical Research Communications (BBRC) Vol. 395 (2010) Nr. 3, pp. 420 - 425Online Full Text: dx.doi.org/