Faculty of Biology

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Prof. Dr. Andrea Musacchio

Functions

  • Honorarprofessor/in, Mikrobiologie I

Current lectures

No current lectures.

Past lectures (max. 10)

No past lectures.

The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.

    Journal articles

  • Polley, Soumitra; Raisch, Tobias; Ghetti, Sabrina; Körner, Marie; Terbeck, Melina; Gräter, Frauke; Raunser, Stefan; Aponte-Santamaría, Camilo; Vetter, Ingrid R.; Musacchio, Andrea
    Structure of the human KMN complex and implications for regulation of its assembly
    In: Nature Structural & Molecular Biology (2024) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Musacchio, Andrea
    Thirty years of structural changes
    In: Nature Structural & Molecular Biology (2024) in press
    Online Full Text: dx.doi.org/
  • Cmentowski, Verena; Ciossani, Giuseppe; d'Amico, Ennio; Wohlgemuth, Sabine; Owa, Mikito; Dynlacht, Brian; Musacchio, Andrea
    RZZ‐Spindly and CENP‐E form an integrated platform to recruit dynein to the kinetochore corona
    In: The EMBO Journal Vol. 42 (2023) Nr. 24, e114838
    Online Full Text: dx.doi.org/
  • Polley, Soumitra; Müschenborn, Helen; Terbeck, Melina; De Antoni, Anna; Vetter, Ingrid R; Dogterom, Marileen; Musacchio, Andrea; Volkov, Vladimir A; Huis in 't Veld, Pim J
    Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
    In: The EMBO Journal Vol. 42 (2023) Nr. 13, e112504
    Online Full Text: dx.doi.org/ (Open Access)
  • Chen, Chu; Piano, Valentina; Alex, Amal; Han, Simon J Y; Huis In 't Veld, Pim J.; Roy, Babhrubahan; Fergle, Daniel; Musacchio, Andrea; Joglekar, Ajit P.; Huis in ’t Veld, Pim J.
    The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex
    In: Nature Communications Vol. 14 (2023) Nr. 1, 1529
    Online Full Text: dx.doi.org/ (Open Access)
  • d'Amico, Ennio A.; Ud Din Ahmad, Misbha; Cmentowski, Verena; Girbig, Mathias; Müller, Franziska; Wohlgemuth, Sabine; Brockmeyer, Andreas; Maffini, Stefano; Janning, Petra; Vetter, Ingrid R.; Carter, Andrew P.; Perrakis, Anastassis; Musacchio, Andrea
    Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin
    In: The Journal of Cell Biology (JCB) Vol. 221 (2022) Nr. 11, e202206131
    Online Full Text: dx.doi.org/ (Open Access)
  • Celestino, Ricardo; Gama, José B; Castro-Rodrigues, Artur F.; Barbosa, Daniel J.; Rocha, Helder; d'Amico, Ennio A.; Musacchio, Andrea; Carvalho, Ana Xavier; Morais-Cabral, João H; Gassmann, Reto; d’Amico, Ennio A.
    JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport
    In: The Journal of Cell Biology (JCB) Vol. 221 (2022) Nr. 8, e202110057
    Online Full Text: dx.doi.org/ (Open Access)
  • Musacchio, Andrea
    On the role of phase separation in the biogenesis of membraneless compartments
    In: The EMBO Journal Vol. 41 (2022) Nr. 5, e109952
    Online Full Text: dx.doi.org/ (Open Access)
  • Martin, Isabel M.; Aponte-Santamaría, Camilo; Schmidt, Lisa; Hedtfeld, Marius; Iusupov, Adel; Musacchio, Andrea; Gräter, Frauke
    Phosphorylation tunes elongation propensity and cohesiveness of INCENP's intrinsically disordered region : Phosphorylation of INCENP disordered region
    In: Journal of Molecular Biology (JMB) Vol. 434 (2022) Nr. 1, 167387
    Online Full Text: dx.doi.org/
  • Huis in 't Veld, Pim J.; Wohlgemuth, Sabine; Koerner, Carolin; Müller, Franziska; Janning, Petra; Musacchio, Andrea
    Reconstitution and use of highly active human CDK1 : Cyclin-B:CKS1 complexes
    In: Protein Science Vol. 31 (2022) Nr. 2, pp. 528 - 537
    Online Full Text: dx.doi.org/ (Open Access)
  • Raisch, Tobias; Ciossani, Giuseppe; d’Amico, Ennio; Cmentowski, Verena; Carmignani, Sara; Maffini, Stefano; Merino, Felipe; Wohlgemuth, Sabine; Vetter, Ingrid R.; Raunser, Stefan; Musacchio, Andrea
    Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores
    In: The EMBO Journal Vol. 41 (2022) Nr. 9, e110411
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Pesenti, Marion E.; Raisch, Tobias; Conti, Duccio; Walstein, Kai; Hoffmann, Ingrid; Vogt, Dorothee; Prumbaum, Daniel; Vetter, Ingrid R.; Raunser, Stefan; Musacchio, Andrea
    Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization
    In: Molecular Cell Vol. 82 (2022) Nr. 11, pp. 2113 - 2131.e8
    Online Full Text: dx.doi.org/ (Open Access)
  • Walstein, Kai; Petrovic, Arsen; Pan, Dongqing; Hagemeier, Birte; Vogt, Dorothee; Vetter, Ingrid R.; Musacchio, Andrea
    Assembly principles and stoichiometry of a complete human kinetochore module
    In: Science Advances Vol. 7 (2021) Nr. 27, eabg1037
    Online Full Text: dx.doi.org/ (Open Access)
  • Singh, Priyanka; Pesenti, Marion E.; Maffini, Stefano; Carmignani, Sara; Hedtfeld, Marius; Petrovic, Arsen; Srinivasamani, Anupallavi; Bange, Tanja; Musacchio, Andrea
    BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis
    In: Molecular Cell Vol. 81 (2021) Nr. 1, pp. 67 - 87.e9
    Online Full Text: dx.doi.org/ (Open Access)
  • Piano, Valentina; Alex, Amal; Stege, Patricia; Maffini, Stefano; Stoppiello, Gerardo A.; Huis In'T Veld, Pim J.; Vetter, Ingrid R.; Musacchio, Andrea
    CDC20 assists its catalytic incorporation in the mitotic checkpoint complex
    In: Science Vol. 371 (2021) Nr. 6524, pp. 67 - 71
    Online Full Text: dx.doi.org/
  • Mueller, Franziska; Friese, Alexandra; Pathe, Claudio; da Silva, Richard Cardoso; Bravo Rodriguez, Kenny; Musacchio, Andrea; Bange, Tanja
    Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization
    In: Science Advances Vol. 7 (2021) Nr. 3, pp. eabc8590
    Online Full Text: dx.doi.org/ (Open Access)
  • van den Boom, Johannes; Kück, Anja; Kravic, Bojana; Müschenborn, Helen; Giesing, Maike; Pan, Dongqing; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Meyer, Hemmo
    Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly
    In: Nature Structural & Molecular Biology Vol. 28 (2021) Nr. 12, pp. 964 - 971
    Online Full Text: dx.doi.org/
  • Alex, Amal; Piano, Valentina; Polley, Soumitra; Stuiver, Marchel; Voss, Stephanie; Ciossani, Giuseppe; Overlack, Katharina; Voss, Beate; Wohlgemuth, Sabine; Petrovic, Arsen; Wu, Yaowen; Selenko, Philipp; Musacchio, Andrea; Maffini, Stefano
    Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology
    In: eLife Vol. 8 (2019) pp. e48287
    Online Full Text: dx.doi.org/ (Open Access)
  • Pan, Dongqing; Walstein, Kai; Take, Annika; Bier, David; Kaiser, Nadine; Musacchio, Andrea
    Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing
    In: Nature Communications Vol. 10 (2019) Nr. 1, pp. 4046
    Online Full Text: dx.doi.org/ (Open Access)
  • Huis In 't Veld, Pim J.; Volkov, Vladimir A.; Stender, Isabelle D.; Musacchio, Andrea; Dogterom, Marileen
    Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling
    In: eLife Vol. 8 (2019) pp. e49539
    Online Full Text: dx.doi.org/ (Open Access)
  • Sacristan, Carlos; Ahmad, Misbha Ud Din; Keller, Jenny; Fermie, Job; Groenewold, Vincent; Tromer, Eelco; Fish, Alexander; Melero, Roberto; Carazo, José María; Klumperman, Judith; Musacchio, Andrea; Perrakis, Anastassis; Kops, Geert JPL
    Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis
    In: Nature Cell Biology Vol. 20 (2018) pp. 800 - 810
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Pesenti, Marion E; Prumbaum, Daniel; Auckland, Philip; Smith, Charlotte M; Faesen, Alex C; Petrovic, Arsen; Erent, Muriel; Maffini, Stefano; Pentakota, Satyakrishna; Weir, John R; Lin, Yu-Chih; Raunser, Stefan; McAinsh, Andrew D; Musacchio, Andrea
    Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80.
    In: Molecular Cell Vol. 71 (2018) Nr. 6, pp. 923 - 939.e10
    Online Full Text: dx.doi.org/ (Open Access)
  • Pan, Dongqing; Brockmeyer, Andreas; Mueller, Franziska; Musacchio, Andrea; Bange, Tanja
    Simplified Protocol for Cross-linking Mass Spectrometry Using the MS-Cleavable Cross-linker DSBU with Efficient Cross-link Identification
    In: Analytical Chemistry Vol. 90 (2018) Nr. 18, pp. 10990 - 10999
    Online Full Text: dx.doi.org/
  • Ciossani, Giuseppe; Overlack, Katharina; Petrovic, Arsen; Huis In 'T Veld, Pim J.; Koerner, Carolin; Wohlgemuth, Sabine; Maffini, Stefano; Musacchio, Andrea
    The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases
    In: The Journal of Biological Chemistry (JBC) Vol. 293 (2018) Nr. 26, pp. 10084 - 10101
    Online Full Text: dx.doi.org/ (Open Access)
  • Weith, Matthias; Seiler, Jonas; van den Boom, Johannes; Kracht, Matthias; Hülsmann, Julia; Primorac, Ivana; Del Pino Garcia, Javier; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Bollen, Mathieu; Meyer, Hemmo
    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
    In: Molecular Cell Vol. 72 (2018) Nr. 4, pp. 766 - 777
    Online Full Text: dx.doi.org/ (Open Access)
  • Musacchio, Andrea; Desai, Arshad
    A molecular view of kinetochore assembly and function
    In: Biology Vol. 6 (2017) Nr. 1, pp. 5
    Online Full Text: dx.doi.org/ (Open Access)
  • Faesen, Alex C.; Thanasoula, Maria; Maffini, Stefano; Breit, Claudia; Müller, Franziska; Van Gerwen, Suzan; Bange, Tanja; Musacchio, Andrea
    Basis of catalytic assembly of the mitotic checkpoint complex
    In: Nature Vol. 542 (2017) Nr. 7642, pp. 498 - 502
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Overlack, Katharina; Bange, Tanja; Weissmann, Florian; Faesen, Alex C.; Maffini, Stefano; Primorac, Ivana; Müller, Franziska; Peters, Jan-Michael; Musacchio, Andrea
    BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling
    In: Current Biology Vol. 27 (2017) Nr. 19, pp. 2915 - 2927.e7
    Online Full Text: dx.doi.org/ (Open Access)
  • Pan, Dongqing; Klare, Kerstin; Petrovic, Arsen; Take, Annika; Walstein, Kai; Singh, Priyanka; Rondelet, Arnaud; Bird, Alexander W; Musacchio, Andrea
    CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading
    In: eLife Vol. 6 (2017) pp. e23352
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Pentakota, Satyakrishna; Zhou, Keda; Smith, Charlotte; Maffini, Stefano; Petrovic, Arsen; Morgan, Garry P.; Weir, John R.; Vetter, Ingrid R.; Musacchio, Andrea; Luger, Karolin
    Decoding the centromeric nucleosome through CENP-N
    In: eLife Vol. 6 (2017) pp. e33442
    Online Full Text: dx.doi.org/ (Open Access)
  • Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Winzker, Michael; Rombaut, Pascaline; Saur, Michael; Petrovic, Arsen; Wehenke, Annemarie; Wohlgemuth, Sabine; Müller, Franziska; Maffini, Stefano; Bange, Tanja; Herzog, Franz; Waldmann, Herbert; Raunser, Stefan; Musacchio, Andrea
    Structure of the RZZ complex and molecular basis of its interaction with Spindly
    In: The Journal of Cell Biology (JCB) Vol. 216 (2017) Nr. 4, pp. 961 - 981
    Online Full Text: dx.doi.org/ (Open Access)
  • Vader, Gerben; Musacchio, Andrea
    The greatest kinetochore show on earth
    In: EMBO Reports Vol. 18 (2017) Nr. 9, pp. 1473 - 1475
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Weir, John R.; Faesen, Alex C.; Klare, Kerstin; Petrovic, Arsen; Basilico, Federica; Fischböck, Josef; Pentakota, Satyakrishna; Keller, Jenny; Pesenti, Marion E.; Pan, Dongqing; Vogt, Doro; Wohlgemuth, Sabine; Herzog, Franz; Musacchio, Andrea
    Insights from biochemical reconstitution into the architecture of human kinetochores
    In: Nature Vol. 537 (2016) Nr. 7619, pp. 249 - 253
    Online Full Text: dx.doi.org/
  • Liu, Yahui; Petrovic, Arsen; Rombaut, Pascaline; Mosalaganti, Shyamal; Keller, Jenny; Raunser, Stefan; Herzog, Franz; Musacchio, Andrea
    Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster
    In: Open Biology Vol. 6 (2016) Nr. 2, 150236
    Online Full Text: dx.doi.org/ (Open Access)
  • Borisy, Gary; Musacchio, Andrea; Janke, Carsten; Howard, Jonathon; Heald, Rebecca; Nogales, Eva
    Microtubules : 50 years on from the discovery of tubulin
    In: Nature Reviews Molecular Cell Biology Vol. 17 (2016) Nr. 5, pp. 322 - 328
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Huisin’T Veld, Pim J.; Jeganathan, Sadasivam; Petrovic, Arsen; Singh, Priyanka; John, Juliane; Krenn, Veronica; Weissmann, Florian; Bange, Tanja; Musacchio, Andrea
    Molecular basis of outer kinetochore assembly on CENP-T
    In: eLife Vol. 5 (2016) pp. e21007
    Online Full Text: dx.doi.org/ (Open Access)
  • Friese, Alexandra; Musacchio, Andrea; Herzog, Franz; Raunser, Stefan; Petrovic, Arsen; Prumbaum, Daniel; Fischböck, Josef; Huis in ‘t Veld,, Pim J.; Faesen, Alex C.
    Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin
    In: Nature Communications Vol. 7 (2016) pp. 11407
    Online Full Text: dx.doi.org/ (Open Access)
  • Pesenti, Marion E.; Weir, John R.; Musacchio, Andrea
    Progress in the structural and functional characterization of kinetochores
    In: Current Opinion in Structural Biology Vol. 37 (2016) pp. 152 - 163
    Online Full Text: dx.doi.org/ (Open Access)
  • O'Connor, Aisling; Maffini, Stefano; Rainey, Michael D.; Kaczmarczyk, Agnieszka; Gaboriau, David; Musacchio, Andrea; Santocanale, Corrado
    Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint
    In: Biology Open: BiO Vol. 5 (2016) Nr. 1, pp. 11 - 19
    Online Full Text: dx.doi.org/ (Open Access)
  • Petrovic, Arsen; Keller, Jenny; Liu, Yahui; Overlack, Katharina; John, Juliane; Dimitrova, Yoana N.; Jenni, Simon; van Gerwen, Suzan; Stege, Patricia; Wohlgemuth, Sabine; Rombaut, Pascaline; Herzog, Franz; Harrison, Stephen C.; Vetter, Ingrid R.; Musacchio, Andrea
    Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
    In: Cell Vol. 167 (2016) Nr. 4, pp. 1028 - 1040.e15
    Online Full Text: dx.doi.org/ (Open Access)
  • Overlack, Katharina; Primorac, Ivana; Vleugel, Mathijs; Krenn, Veronica; Maffini, Stefano; Hoffmann, Ingrid; Kops, Geert J. P. L.; Musacchio, Andrea
    A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
    In: eLife Vol. 4 (2015) pp. e05269
    Online Full Text: dx.doi.org/ (Open Access)
  • Klare, Kerstin; Weir, John R.; Basilico, Federica; Zimniak, Tomasz; Massimiliano, Lucia; Ludwigs, Nina; Herzog, Franz; Musacchio, Andrea
    CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores
    In: The Journal of Cell Biology (JCB) Vol. 210 (2015) Nr. 1, pp. 11 - 22
    Online Full Text: dx.doi.org/ (Open Access)
  • Musacchio, Andrea
    Closing the Mad2 cycle : chromosome separation is regulated by a cycle that involves a protein undergoing an unusual topological conversion
    In: eLife Vol. 4 (2015) pp. e08283
    Online Full Text: dx.doi.org/ (Open Access)
  • Altenfeld, Anika; Wohlgemuth, Sabine; Wehenkel, Annemarie; Vetter, Ingrid R.; Musacchio, Andrea
    Complex assembly, crystallization and preliminary x-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex
    In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications Vol. 71 (2015) Nr. 4, pp. 438 - 442
    Online Full Text: dx.doi.org/ (Open Access)
  • Meyer, Rebecca; Faesen, Alex; Vogel, Katrin; Jeganathan, Sadasivam; Musacchio, Andrea; Niemeyer, Christof M.
    DNA-directed assembly of capture tools for constitutional studies of large protein complexes
    In: Small Vol. 11 (2015) Nr. 22, pp. 2669 - 2674
    Online Full Text: dx.doi.org/
  • Tachiwana, Hiroaki; Müller, Sebastian; Blümer, Julia; Klare, Kerstin; Musacchio, Andrea; Almouzni, Geneviève
    HJURP involvement in De Novo CenH3CENP-A and CENP-C recruitment
    In: Cell Reports Vol. 11 (2015) Nr. 1, pp. 22 - 32
    Online Full Text: dx.doi.org/ (Open Access)
  • Breit, Claudia; Bange, Tanja; Petrović, Arsen N.; Weir, John R.; Müller, Franziska; Vogt, Doro; Musacchio, Andrea
    Role of intrinsic and extrinsic factors in the regulation of the mitotic checkpoint kinase Bub1
    In: PLoS ONE Vol. 10 (2015) Nr. 12, pp. 0144673
    Online Full Text: dx.doi.org/ (Open Access)
  • Faesen, Alex C.; Musacchio, Andrea
    The (phospho) needle in the (MELT) haystack
    In: Molecular Cell Vol. 57 (2015) Nr. 5, pp. 765 - 766
    Online Full Text: dx.doi.org/ (Open Access)
  • Krenn, Veronica; Musacchio, Andrea
    The Aurora B kinase in chromosome bi-orientation and spindle checkpoint signaling
    In: Frontiers in Oncology Vol. 5 (2015) pp. 225
    Online Full Text: dx.doi.org/ (Open Access)
  • Musacchio, Andrea
    The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics
    In: Current Biology Vol. 25 (2015) Nr. 20, pp. R1002 - R1018
    Online Full Text: dx.doi.org/ (Open Access)
  • Vader, Gerben; Musacchio, Andrea
    HORMA domains at the heart of meiotic chromosome dynamics
    In: Developmental Cell Vol. 31 (2014) Nr. 4, pp. 389 - 391
    Online Full Text: dx.doi.org/ (Open Access)
  • Eiteneuer, Annika; Seiler, Jonas; Weith, Matthias; Beullens, Monique; Lesage, Bart; Krenn, Veronica; Musacchio, Andrea; Bollen, Mathieu; Meyer, Hemmo
    Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1
    In: The EMBO Journal Vol. 33 (2014) Nr. 22, pp. 2704 - 2720
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Krenn, Veronica; Overlack, Katharina; Primorac, Ivana; Van Gerwen, Suzan; Musacchio, Andrea
    KI motifs of human Knl1 enhance assembly of comprehensive spindle checkpoint complexes around MELT repeats
    In: Current Biology Vol. 24 (2014) Nr. 1, pp. 29 - 39
    Online Full Text: dx.doi.org/ (Open Access)
  • Petrovic, Arsen; Mosalaganti, Shyamal; Keller, Jenny; Mattiuzzo, Marta; Overlack, Katharina; Krenn, Veronica; De Antoni, Anna; Wohlgemuth, Sabine; Cecatiello, Valentina; Pasqualato, Sebastiano; Raunser, Stefan; Musacchio, Andrea
    Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization
    In: Molecular Cell Vol. 53 (2014) Nr. 4, pp. 591 - 605
    Online Full Text: dx.doi.org/ (Open Access)
  • Basilico, Federica; Maffini, Stefano; Weir, John R.; Prumbaum, Daniel; Rojas, Ana M.; Zimniak, Tomasz; De Antoni, Anna; Jeganathan, Sadasivam; Voss, Beate; Van Gerwen, Suzan; Krenn, Veronica; Massimiliano, Lucia; Valencia, Alfonso; Vetter, Ingrid R.; Herzog, Franz; Raunser, Stefan; Pasqualato, Sebastiano; Musacchio, Andrea
    The pseudo GTPase CENP-M drives human kinetochore assembly
    In: eLife Vol. 3 (2014) pp. e02978
    Online Full Text: dx.doi.org/ (Open Access)
  • Overlack, Katharina; Krenn, Veronica; Musacchio, Andrea
    When Mad met Bub
    In: EMBO Reports Vol. 15 (2014) Nr. 4, pp. 326 - 328
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Primorac, Ivana; Weir, John R.; Chiroli, Elena; Gross, Fridolin; Hoffmann, Ingrid; Van Gerwen, Suzan; Ciliberto, Andrea; Musacchio, Andrea
    Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling
    In: eLife Vol. 2 (2013) pp. e01030
    Online Full Text: dx.doi.org/ (Open Access)
  • Earnshaw, William C.; Allshire, Robin C.; Black, Ben E.; Bloom, Kerry; Brinkley, Bill R.; Brown, William; Cheeseman, Iain M.; Choo, Kong H. A.; Copenhaver, Gregory P.; DeLuca, Jennifer G.; Desai, Arshad; Diekmann, Stephan; Erhardt, Sylvia; Fitzgerald-Hayes, Molly; Foltz, Daniel; Fukagawa, Tatsuo; Gassmann, Reto; Gerlich, Daniel W.; Glover, David M.; Gorbsky, Gary J.; Harrison, Stephen C.; Heun, Patrick; Hirota, Toru; Jansen, Lars E. T.; Karpen, Gary; Kops, Geert J. P. L.; Lampson, Michael A.; Lens, Susanne M.; Losada, Ana; Luger, Karolin; Maiato, Helder; Maddox, Paul S.; Margolis, Robert L.; Masumoto, Hiroshi; McAinsh, Andrew D.; Mellone, Barbara G.; Meraldi, Patrick; Musacchio, Andrea; Oegema, Karen; O'Neill, Rachel J.; Salmon, Edward D.; Scott, Kristin C.; Straight, Aaron F.; Stukenberg, Peter T.; Sullivan, Beth A.; Sullivan, Kevin F.; Sunkel, Claudio E.; Swedlow, Jason R.; Walczak, Claire E.; Warburton, Peter E.; Westermann, Stefan; Willard, Huntington F.; Wordeman, Linda; Yanagida, Mitsuhiro; Yen, Tim J.; Yoda, Kinya; Cleveland, Don W.
    Esperanto for histones : CENP-A, not CenH3, is the centromeric histone H3 variant
    In: Chromosome Research Vol. 21 (2013) Nr. 2, pp. 101 - 106
    Online Full Text: dx.doi.org/
  • Hagemann, S.; Wohlschläger, Jeremias; Bertram, S.; Levkau, Bodo; Musacchio, Andrea; Conway, E. M.; Möllmann, D.; Kneiseler, G.; Pless-Petig, G.; Lorenz, Kristina; Sitek, B.; Baba, Hideo Andreas
    Loss of survivin influences liver regeneration and is associated with impaired aurora B function
    In: Cell Death and Differentiation Vol. 20 (2013) Nr. 6, pp. 834 - 844
    Online Full Text: dx.doi.org/
  • Primorac, Ivana; Musacchio, Andrea
    Panta rhei : the APC/C at steady state
    In: The Journal of Cell Biology (JCB) Vol. 201 (2013) Nr. 2, pp. 177 - 189
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Ciliberto, Andrea
    The spindle-assembly checkpoint and the beauty of self-destruction : Erratum
    In: Nature Structural & Molecular Biology Vol. 20 (2013) Nr. 2, pp. 244
    Online Full Text: dx.doi.org/
  • De Antoni, Anna; Maffini, Stefano; Knapp, Stefan; Musacchio, Andrea; Santaguida, Stefano
    A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B
    In: The Journal of Cell Biology (JCB) Vol. 199 (2012) Nr. 2, pp. 269 - 284
    Online Full Text: dx.doi.org/
  • Elkins, Jonathan M.; Santaguida, Stefano; Musacchio, Andrea; Knapp, Stefan
    Crystal structure of human Aurora B in complex with INCENP and VX-680
    In: Journal of Medicinal Chemistry Vol. 55 (2012) Nr. 17, pp. 7841 - 7848
    Online Full Text: dx.doi.org/ (Open Access)
  • Musacchio, Andrea
    Q & A : Andrea Musacchio
    In: Current Biology Vol. 22 (2012) Nr. 14, pp. R552 - R554
    Online Full Text: dx.doi.org/
  • Mariani, Luca; Chiroli, Elena; Nezi, Luigi; Müller, Heiko; Piatti, Simonetta; Musacchio, Andrea; Ciliberto, Andrea
    Role of the Mad2 dimerization interface in the spindle assembly checkpoint independent of kinetochores
    In: Current Biology Vol. 22 (2012) Nr. 20, pp. 1900 - 1908
    Online Full Text: dx.doi.org/
  • Kwiatkowski, Nicholas; Deng, Xianming; Wang, Jinhua; Tan, Li; Villa, Fabrizio; Santaguida, Stefano; Huang, Hsiao-Chun; Mitchison, Tim; Musacchio, Andrea; Gray, Nathanael
    Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen
    In: ACS Chemical Biology Vol. 7 (2012) Nr. 1, pp. 185 - 196
    Online Full Text: dx.doi.org/
  • Krenn, Veronica; Wehenkel, Annemarie; Li, Xiaozheng; Santaguida, Stefano; Musacchio, Andrea
    Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction
    In: The Journal of Cell Biology (JCB) Vol. 196 (2012) Nr. 4, pp. 451 - 467
    Online Full Text: dx.doi.org/
  • DeLuca, Jennifer G.; Musacchio, Andrea
    Structural organization of the kinetochore-microtubule interface
    In: Current Opinion in Cell Biology Vol. 24 (2012) Nr. 1, pp. 48 - 56
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Ciliberto, Andrea
    The spindle-assembly checkpoint and the beauty of self-destruction
    In: Nature Structural & Molecular Biology Vol. 19 (2012) Nr. 11, pp. 1059 - 1061
    Online Full Text: dx.doi.org/
  • Balzano, Deborah; Santaguida, Stefano; Musacchio, Andrea; Villa, Fabrizio
    A general framework for inhibitor resistance in protein kinases
    In: Chemistry and Biology Vol. 18 (2011) Nr. 8, pp. 966 - 975
    Online Full Text: dx.doi.org/
  • Balzano, Deborah; Santaguida, Stefano; Musacchio, Andrea; Villa, Fabrizio
    A general framework for inhibitor resistance in protein kinases : Erratum
    In: Chemistry and Biology Vol. 18 (2011) Nr. 10, pp. 1341
    Online Full Text: dx.doi.org/
  • Mattiuzzo, Marta; Vargiu, Giulia; Totta, Pierangela; Fiore, Mario; Ciferri, Claudio; Musacchio, Andrea; Degrassi, Francesca
    Abnormal kinetochore-generated pulling forces from expressing a n-terminally modified Hec1
    In: PLoS ONE Vol. 6 (2011) Nr. 1, pp. e16307
    Online Full Text: dx.doi.org/ (Open Access)
  • Screpanti, Emanuela; De Antoni, Anna; Alushin, Gregory M.; Petrovic, Arsen; Melis, Tiziana; Nogales, Eva; Musacchio, Andrea
    Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore
    In: Current biology Vol. 21 (2011) Nr. 5, pp. 391 - 398
    Online Full Text: dx.doi.org/
  • Santaguida, Stefano; Vernieri, Claudio; Villa, Fabrizio; Ciliberto, Andrea; Musacchio, Andrea
    Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction
    In: The EMBO Journal Vol. 30 (2011) Nr. 8, pp. 1508 - 1519
    Online Full Text: dx.doi.org/
  • Varetti, Gianluca; Guida, Claudia; Santaguida, Stefano; Chiroli, Elena; Musacchio, Andrea
    Homeostatic control of mitotic arrest
    In: Molecular cell Vol. 44 (2011) Nr. 5, pp. 710 - 720
    Online Full Text: dx.doi.org/
  • Perrakis, Anastassis; Musacchio, Andrea; Cusack, Stephen; Petosa, Carlo
    Investigating a macromolecular complex : the toolkit of methods
    In: Journal of Structural Biology Vol. 175 (2011) Nr. 2, pp. 106 - 112
    Online Full Text: dx.doi.org/
  • Alexander, Jes; Lim, Daniel; Joughin, Brian A.; Hegemann, Björn; Hutchins, James R. A.; Ehrenberger, Tobias; Ivins, Frank; Sessa, Fabio; Hudecz, Otto; Nigg, Erich A.; Fry, Andrew M.; Musacchio, Andrea; Stukenberg, P. Todd; Mechtler, Karl; Peters, Jan-Michael; Smerdon, Stephen J.; Yaffe, Michael B.
    Spatial exclusivity combined with positive and negative selection of phosphorylation motifs Is the basis for context-dependent mitotic signaling
    In: Science signaling Vol. 4 (2011) Nr. 179, 1-15, art. no. ra42
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea
    Spindle assembly checkpoint : the third decade
    In: Philosophical transactions of the Royal Society : series B, biological sciences Vol. 366 (2011) Nr. 1584, pp. 3595 - 3604
    Online Full Text: dx.doi.org/
  • Maspero, Elena; Mari, Sara; Valentini, Eleonora; Musacchio, Andrea; Fish, Alexander; Pasqualato, Sebastiano; Polo, Simona
    Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation
    In: EMBO Reports Vol. 12 (2011) Nr. 4, pp. 342 - 349
    Online Full Text: dx.doi.org/
  • Maure, Jean-François; Komoto, Shinya; Oku, Yusuke; Mino, Akihisa; Pasqualato, Sebastiano; Natsume, Kayo; Clayton, Lesley; Musacchio, Andrea; Tanaka, Tomoyuki U.
    The Ndc80 loop region facilitates formation of kinetochore attachment to the dynamic microtubule plus end
    In: Current biology Vol. 21 (2011) Nr. 3, pp. 207 - 213
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea
    Travel notes from the equatorial circle
    In: Cell Vol. 146 (2011) Nr. 4, pp. 499 - 501
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea
    Cell cycle : deconstructing tension
    In: Current biology Vol. 20 (2010) Nr. 15, pp. R634 - R637
    Online Full Text: dx.doi.org/
  • Santaguida, Stefano; Tighe, Anthony; D'Alise, Anna M.; Taylor, Stephen S.; Musacchio, Andrea
    Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
    In: The Journal of Cell Biology (JCB) Vol. 190 (2010) Nr. 1, pp. 73 - 87
    Online Full Text: dx.doi.org/
  • Civril, Filiz; Wehenkel, Annemarie; Giorgi, Federico M.; Santaguida, Stefano; Di Fonzo, Andrea; Grigorean, Gabriela; Ciccarelli, Francesca D.; Musacchio, Andrea
    Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery
    In: Structure Vol. 18 (2010) Nr. 5, pp. 616 - 626
    Online Full Text: dx.doi.org/
  • Hewitt, Laura; Tighe, Anthony; Santaguida, Stefano; White, Anne M.; Jones, Clifford D.; Musacchio, Andrea; Green, Stephen; Taylor, Stephen S.
    Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex
    In: The Journal of Cell Biology (JCB) Vol. 190 (2010) Nr. 1, pp. 25 - 34
    Online Full Text: dx.doi.org/
  • Petrovic, Arsen; Pasqualato, Sebastiano; Dube, Prakash; Krenn, Veronica; Santaguida, Stefano; Cittaro, Davide; Monzani, Silvia; Massimiliano, Lucia; Keller, Jenny; Tarricone, Aldo; Maiolica, Alessio; Stark, Holger; Musacchio, Andrea
    The MIS12 complex is a protein interaction hub for outer kinetochore assembly
    In: The Journal of Cell Biology (JCB) Vol. 190 (2010) Nr. 5, pp. 835 - 852
    Online Full Text: dx.doi.org/
  • Villa, Fabrizio; Capasso, Paola; Tortorici, Marcello; Forneris, Federico; De Marco, Ario; Mattevi, Andrea; Musacchio, Andrea
    Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 106 (2009) Nr. 48, pp. 20204 - 20209
    Online Full Text: dx.doi.org/
  • Nezi, Luigi; Musacchio, Andrea
    Sister chromatid tension and the spindle assembly checkpoint
    In: Current Opinion in Cell Biology Vol. 21 (2009) Nr. 6, pp. 785 - 795
    Online Full Text: dx.doi.org/
  • Amabile, Giovanni; D'Alise, Anna M.; Iovino, Mariangela; Jones, Philip; Santaguida, Stefano; Musacchio, Andrea; Taylor, Stephen; Cortese, Riccardo
    The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts
    In: Cell death and differentiation Vol. 16 (2009) Nr. 2, pp. 321 - 330
    Online Full Text: dx.doi.org/
  • Santaguida, Stefano; Musacchio, Andrea
    The life and miracles of kinetochores
    In: The EMBO Journal Vol. 28 (2009) Nr. 17, pp. 2511 - 2531
    Online Full Text: dx.doi.org/
  • Andersen, Carsten B.; Wan, Yongqin; Chang, Jae W.; Riggs, Blake; Lee, Christian; Liu, Yi; Sessa, Fabio; Villa, Fabrizio; Kwiatkowski, Nicholas; Suzuki, Melissa; Nallan, Laxman; Heald, Rebecca; Musacchio, Andrea; Gray, Nathanael S.
    Discovery of selective aminothiazole aurora kinase inhibitors
    In: ACS Chemical Biology Vol. 3 (2008) Nr. 3, pp. 180 - 192
    Online Full Text: dx.doi.org/
  • Ciferri, Claudio; Pasqualato, Sebastiano; Screpanti, Emanuela; Varetti, Gianluca; Santaguida, Stefano; Dos Reis, Gabriel; Maiolica, Alessio; Polka, Jessica; De Luca, Jennifer G.; De Wulf, Peter; Salek, Mogjiborahman; Rappsilber, Juri; Moores, Carolyn A.; Salmon, Edward D.; Musacchio, Andrea
    Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex
    In: Cell Vol. 133 (2008) Nr. 3, pp. 427 - 439
    Online Full Text: dx.doi.org/
  • Civril, Filiz; Musacchio, Andrea
    Spindly attachments
    In: Genes and development Vol. 22 (2008) Nr. 17, pp. 2302 - 2307
    Online Full Text: dx.doi.org/
  • Varetti, Gianluca; Musacchio, Andrea
    The spindle assembly checkpoint
    In: Current biology Vol. 18 (2008) Nr. 14, pp. R591 - R595
    Online Full Text: dx.doi.org/
  • Varetti, Gianluca; Musacchio, Andrea
    The spindle assembly checkpoint : correction
    In: Current biology Vol. 18 (2008) Nr. 18, pp. 1444
    Online Full Text: dx.doi.org/
  • Mapelli, Marina; Musacchio, Andrea
    MAD contortions : conformational dimerization boosts spindle checkpoint signaling
    In: Current opinion in structural biology Vol. 17 (2007) Nr. 6, pp. 716 - 725
    Online Full Text: dx.doi.org/
  • Plyte, Simon; Musacchio, Andrea
    PLK1 inhibitors : setting the mitotic death trap
    In: Current biology Vol. 17 (2007) Nr. 8, pp. R280 - R283
    Online Full Text: dx.doi.org/
  • Mapelli, Marina; Massimiliano, Lucia; Santaguida, Stefano; Musacchio, Andrea
    The Mad2 conformational dimer : structure and implications for the spindle assembly checkpoint
    In: Cell Vol. 131 (2007) Nr. 4, pp. 730 - 743
    Online Full Text: dx.doi.org/
  • Ciferri, Claudio; Musacchio, Andrea; Petrovic, Arsen
    The Ndc80 complex : hub of kinetochore activity
    In: FEBS Letters Vol. 581 (2007) Nr. 15, pp. 2862 - 2869
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Salmon, Edward D.
    The spindle-assembly checkpoint in space and time
    In: Nature reviews : molecular cell biology Vol. 8 (2007) Nr. 5, pp. 379 - 393
    Online Full Text: dx.doi.org/
  • Derewenda, Urszula; Tarricone, Cataldo; Choi, Won C.; Cooper, David R.; Lukasik, Steve; Perrina, Franco; Tripathy, Ashutosh; Kim, Myung H.; Cafiso, David S.; Musacchio, Andrea; Derewenda, Zygmunt S.
    The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly
    In: Structure Vol. 15 (2007) Nr. 11, pp. 1467 - 1481
    Online Full Text: dx.doi.org/
  • Nezi, Luigi; Rancati, Giulia; De Antoni, Anna; Pasqualato, Sebastiano; Piatti, Simonetta; Musacchio, Andrea
    Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae
    In: The Journal of Cell Biology (JCB) Vol. 174 (2006) Nr. 1, pp. 39 - 51
    Online Full Text: dx.doi.org/
  • Penengo, Lorenza; Mapelli, Marina; Murachelli, Andrea G.; Confalonieri, Stefano; Magri, Laura; Musacchio, Andrea; Di Fiore, Pier P.; Polo, Simona; Schneider, Thomas R.
    Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin
    In: Cell Vol. 124 (2006) Nr. 6, pp. 1183 - 1195
    Online Full Text: dx.doi.org/
  • Mapelli, Marina; Filipp, Fabian V.; Rancati, Giulia; Massimiliano, Lucia; Nezi, Luigi; Stier, Gunter; Hagan, Robert S.; Confalonieri, Stefano; Piatti, Simonetta; Sattler, Michael; Musacchio, Andrea
    Determinants of conformational dimerization of Mad2 and its inhibition by p31comet
    In: The EMBO Journal Vol. 25 (2006) Nr. 6, pp. 1273 - 1284
    Online Full Text: dx.doi.org/
  • Vink, Martin; Simonetta, Marco; Transidico, Pietro; Ferrari, Karin; Mapelli, Marina; De Antoni, Anna; Massimiliano, Lucia; Ciliberto, Andrea; Faretta, Mario; Salmon, Edward D.; Musacchio, Andrea
    In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics
    In: Current biology Vol. 16 (2006) Nr. 8, pp. 755 - 766
    Online Full Text: dx.doi.org/
  • DeLuca, Jennifer G.; Gall, Walter E.; Ciferri, Claudio; Cimini, Daniela; Musacchio, Andrea; Salmon, Edward D.
    Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
    In: Cell Vol. 127 (2006) Nr. 5, pp. 969 - 982
    Online Full Text: dx.doi.org/
  • Ciferri, Claudio; De Luca, Jennifer; Monzani, Silvia; Ferrari, Karin J.; Ristic, Dejan; Wyman, Claire; Stark, Holger; Kilmartin, John; Salmon, Edward D.; Musacchio, Andrea
    Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore
    In: The Journal of Biological Chemistry (JBC) Vol. 280 (2005) Nr. 32, pp. 29088 - 29095
    Online Full Text: dx.doi.org/
  • De Antoni, Anna; Sala, Valeria; Musacchio, Andrea
    Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2
    In: Philosophical transactions of the Royal Society : series B, biological sciences Vol. 360 (2005) Nr. 1455, pp. 637 - 648
    Online Full Text: dx.doi.org/
  • Sessa, Fabio; Mapelli, Marina; Ciferri, Claudio; Tarricone, Cataldo; Areces, Liliana B.; Schneider, Thomas R.; Stukenberg, P. Todd; Musacchio, Andrea
    Mechanism of Aurora B activation by INCENP and inhibition by Hesperadin
    In: Molecular cell Vol. 18 (2005) Nr. 3, pp. 379 - 391
    Online Full Text: dx.doi.org/
  • De Antoni, Anna; Pearson, Chad G.; Cimini, Daniela; Canman, Julie C.; Sala, Valeria; Nezi, Luigi; Mapelli, Marina; Sironi, Lucia; Faretta, Mario; Salmon, Edward D.; Musacchio, Andrea
    The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
    In: Current biology Vol. 15 (2005) Nr. 3, pp. 214 - 225
    Online Full Text: dx.doi.org/
  • Mapelli, Marina; Musacchio, Andrea
    The structural perspective on CDK5
    In: Neurosignals Vol. 12 (2003) Nr. 4-5, pp. 164 - 172
    Online Full Text: dx.doi.org/
  • Sironi, Lucia; Mapelli, Marina; Knapp, Stefan; De Antoni, Anna; Jeang, Kuan‐Teh; Musacchio, Andrea
    Crystal structure of the tetrameric Mad1-Mad2 core complex : implications of 'safety belt' binding mechanism for the spindle checkpoint
    In: The EMBO Journal Vol. 21 (2002) Nr. 10, pp. 2496 - 2506
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Hardwick, Kevin G.
    The spindle checkpoint : structural insights into dynamic signalling
    In: Nature reviews : molecular cell biology Vol. 3 (2002) Nr. 10, pp. 731 - 741
    Online Full Text: dx.doi.org/
  • Fraschini, Roberta; Beretta, Alessia; Sironi, Lucia; Musacchio, Andrea; Lucchini, Giovanna; Piatti, Simonetta
    Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores
    In: The EMBO Journal Vol. 20 (2001) Nr. 23, pp. 6648 - 6659
    Online Full Text: dx.doi.org/
  • Sironi, Lucia; Melixetian, Marina; Faretta, Mario; Prosperini, Elena; Helin, Kristian; Musacchio, Andrea
    Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for spindle checkpoint
    In: The EMBO Journal Vol. 20 (2001) Nr. 22, pp. 6371 - 6382
    Online Full Text: dx.doi.org/
  • Tarricone, Cataldo; Dhavan, Rani; Peng, Junmin; Areces, Liliana B.; Tsai, Li-Huei; Musacchio, Andrea
    Structure and regulation of the CDK5-p25nck5a complex
    In: Molecular cell Vol. 8 (2001) Nr. 3, pp. 657 - 669
    Online Full Text: dx.doi.org/
  • Orrico, Alfredo; Galli, Lucia; Falciani, Michela; Bracci, Martina; Cavaliere, Maria L.; Rinaldi, Maria M.; Musacchio, Andrea; Sorrentino, Vincenzo
    A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome)
    In: FEBS Letters Vol. 478 (2000) Nr. 3, pp. 216 - 220
    Online Full Text: dx.doi.org/
  • Kang, Hyun; Freund, Christian; Duke‐Cohan, Jonathan S.; Musacchio, Andrea; Wagner, Gerhard; Rudd, Christopher E.
    SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55
    In: The EMBO Journal Vol. 19 (2000) Nr. 12, pp. 2889 - 2899
    Online Full Text: dx.doi.org/
  • Mongioví, Adriana M.; Romano, Pascale R.; Panni, Simona; Mendoza, Manuel; Wong, William T.; Musacchio, Andrea; Cesareni, Gianni; Di Fiore, Pier P.
    A novel peptide-SH3 interaction
    In: The EMBO Journal Vol. 18 (1999) Nr. 19, pp. 5300 - 5309
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Smith, Corinne J.; Roseman, Alan M.; Harrison, Stephen C.; Kirchhausen, Tomas; Pearse, Barbara M. F.
    Functional organization of clathrin in coats : combining electron cryomicroscopy and x-ray crystallography
    In: Molecular cell Vol. 3 (1999) Nr. 6, pp. 761 - 770
    Online Full Text: dx.doi.org/
  • Ter Haar, Ernst; Musacchio, Andrea; Harrison, Stephen C.; Kirchhausen, Tomas
    Atomic structure of clathrin : a β propeller terminal domain joins an α zigzag linker
    In: Cell Vol. 95 (1998) Nr. 4, pp. 563 - 573
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Cantley, Lewis C.; Harrison, Stephen C.
    Crystal structure of the breakpoint cluster region homology domain from phosphoinositide 3-kinase p85 alpha subunit
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 93 (1996) Nr. 25, pp. 14373 - 14378
    Online Full Text: dx.doi.org/
  • Saraste, Matti; Musacchio, Andrea
    Backwards and forwards binding
    In: Nature structural biology Vol. 1 (1994) Nr. 12, pp. 835 - 837
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Wilmanns, Matthias; Saraste, Matti
    Structure and function of the SH3 domain
    In: Progress in biophysics and molecular biology Vol. 61 (1994) Nr. 3, pp. 283 - 297
    Online Full Text: dx.doi.org/
  • Noble, Martin E. M.; Musacchio, Andrea; Saraste, Matti; Courtneidge, Sara A.; Wierenga, Rik K.
    Crystal structure of the SH3 domain in human Fyn : comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin
    In: The EMBO Journal Vol. 12 (1993) Nr. 7, pp. 2617 - 2624
    Online Full Text
  • Van der Oost, John; Musacchio, Andrea; Pauptit, Richard A.; Ceska, Thomas A.; Wierenga, Rik K.; Saraste, Matti
    Crystallization and preliminary x-ray analysis of the periplasmic fragment of CyoA-a subunit of the Escherichia coli cytochrome o complex
    In: Journal of Molecular Biology (JMB) Vol. 229 (1993) Nr. 3, pp. 794 - 796
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Gibson, Toby; Rice, Peter; Thompson, Julie; Saraste, Matti
    The PH domain : a common piece in the structural pathcwork of signalling proteins
    In: Trends in biochemical sciences Vol. 18 (1993) Nr. 9, pp. 343 - 348
    Online Full Text: dx.doi.org/
  • Musacchio, Andrea; Noble, Martin; Pauptit, Richard; Wierenga, Rik; Saraste, Matti
    Crystal structure of a Src-homology 3 (SH3) domain
    In: Nature Vol. 359 (1992) Nr. 6398, pp. 851 - 855
    Online Full Text: dx.doi.org/

    • Articles

  • Pleuger, Richard; Cozma, Christian; Hohoff, Simone; Denkhaus, Christian; Dudziak, Alexander; Kaschani, Farnusch; Musacchio, Andrea; Vetter, Ingrid R.; Westermann, Stefan
    Ipl1-controlled attachment maturation regulates Mps1 association with its kinetochore receptor
    (2023) 43 Seiten
    Online Full Text: dx.doi.org/ (Open Access)
  • d'Amico, Ennio; Ud Din Ahmad, Misbha; Cmentowski, Verena; Girbig, Mathias; Mueller, Franziska; Wohlgemuth, Sabine; Brockmeyer, Andreas; Maffini, Stefano; Janning, Petra; Vetter, Ingrid R.; Carter, Andrew P.; Perrakis, Anastassis; Musacchio, Andrea
    Conformational transitions of the mitotic adaptor Spindly underlie its interaction with Dynein and Dynactin
    (2022)
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)

    • Prefaces/Postfaces

  • Musacchio, Andrea; Helin, Kristian
    Cell cycle, differentiation and disease : editorial overview
    In: Current Opinion in Cell Biology Vol. 25 (2013) Nr. 6, pp. 673 - 675
    Online Full Text: dx.doi.org/