Lectures
2025
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Breaking Boundaries in Separation Science: LCxLC-IM-qTOF-MS |
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Revolution or complement? Can ion mobility mass spectrometry replace chromatography? |
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Breaking Boundaries in Separation Science: LCxLC-IM-qTOF-MS |
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Increase speed and/or confidence in metabolomics |
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Boosting the separation power of LCxLC |
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First experiences with next-generation ion mobility mass spectrometry |
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Breaking Boundaries in Separation Science: Coupling Ion Mobility Mass Spectrometry and comprehensive Two-Dimensional Liquid Chromatography |
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Less is more: Data reduction for coupling LCxLC with ion mobility mass spectrometry |
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Development of a MULTI-2D LC×LC-ESI/TPI-DUAL SOURCE-QTOF-MS for the analysis of complex samples |
2024
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Ultra-high-resolution MS and ever more powerful ion mobility mass spectrometers, and we are still talking about chromatography: why? |
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Ultra-high-resolution MS and ever more powerful ion mobility mass spectrometers, and we are still talking about chromatography: why? |
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Ultra-high-resolution MS and ever more powerful ion mobility mass spectrometers, and we are still talking about chromatography: why? |
2023
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Ultra-high-resolution MS and ever more powerful ion mobility mass spectrometers, and we are still talking about chromatography: why? |
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Various applications of GC-El-qTOF-MS in the field of metabolomics, lipidomics and environment |
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On the way to single-cell metabolome analysis |
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On the way to single-cell metabolome analysis |
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Development of a new ionization source for single cell metabolome |
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How to solve problems in non-targeted analysis |
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Why GC-EI-MS when you can do better? |
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How to solve problems in non-targeted analysis |
2022
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APCI, APPI, APLI, and DBD: Uncommon ionization methods for GC-MS |
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2D-LC: Hype or huge Potential? |
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Why use GC-EI-MS when you can do better? |
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Why use GC-EI-MS when you can do better? |
2021
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APCI, APPI, APLI, and DBD: Uncommon ionisation methods for GC- MS |
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APCI, APPI, APLI and DBD as powerful ionization methods for GC-MS |
2020
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Reduction of the elution power of the transfer solution to optimize a 2D-LC |
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Analysis of complex samples with LCxLC, LC-IMS or µLC+LC-IMS coupled to qTOF-MS: Who is the winner? |
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To the limits of feasibility: 2D-LC-ACD-HRdm-IM-qTOF-MS |
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The power of IM-MS and the benefit of multiplexing |
2019
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Chinese Herbs Analysis: The Power of Chromatography in Combination with Ion Mobility-Mass Spectrometry |
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Mass spectrometry: What needs to be improved? |
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Challenges in single-cell analysis with mass spectrometry |
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Use of SFC-IM-qTOF-MS for the analysis of sugars and lipids |
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The power of chromatography in combination with ion mobility-mass spectrometry |
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The power of chromatography in combination with ion mobility-mass spectrometry |
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How using an at-column dilution (ACD) Mmodulator can improve 2D-LC Analysis |
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2D-LC-IM-qTOF-MS as a generic analytical method for the analysis of complex samples |
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From 1D-LC with 1000-mm columns to LC+LC-IM-qTOF-MS |
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Ionenmobilitäts-Massenspektrometrie als leistungsstarkes Tool für die target, suspected target und non-target Umweltanalytik |
2018
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µLC+LC-IM-qTOF-MS for complex samples such as lipidome or proteome |
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Five-dimensional analysis (LC+LC-IM-qTOF-MS) for complex samples such as metablome, lipidome or proteome |
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LC+LC- and GC+GC-IMS-qTOF-MS as a generic analytical platform and first results with a new GC-APCI ion source |
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Thousands of separated signals in a four-dimensional separation approach: How can we manage the data |
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From one- to five-dimensional analysis platform: pros and cons |
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Multidimensional Chromatography coupled with Ion-Mobility Mass Spectrometry: Enough is enough |
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LC+LC- and GC+GC-IMS-qTOF-MS as a generic analytical platform and first results with a new GC-APCI ion source |
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LC+LC- and GC+GC-IMS-qTOF-MS in combination with a CCS data base as a generic analytical platform |
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Einsatz der Ionenmobilitäts-Massenspektrometrie für suspected und non-target Fragestellungen: Ein kritischer Überblick |
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LC+LC- and GC+GC-IMS-qTOF-MS as a generic analytical platform |
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Multidimensional Chromatography coupled with Ion Mobility - Mass Spectrometry: Hype or Ripe? |
2015 - 2017
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Multidimensional Chromatography coupled with Ion Mobility - Mass Spectrometry: Hype or Ripe? |
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LC+LC- and GC+GC-IM-qTOF-MS as a potential tool in non-target analysis |
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Novel trends in mass spectrometry |
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2D-LC and 2D-GC coupled with IMS-qTOF-MS as a potential tool for the analysis of Traditional Chinese Herbs |
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A four-dimensional separation method for the comprehensive analysis of natural products |
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2D-Chromatography coupled to IM-qTOF-MS for the analysis of complex samples such as medicinal plants |
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New and unusual ionization methods for mass spectrometric analysis of nonpolar substances |
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A novel multi-dimensional separation approach for Lipidomics |
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LC+LC- and GC+GC-IM-qTOF-MS as a potential tool in non-target analysis |
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Ion mobility spectroscopy as a powerful separation dimension in LC-MS |
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GC-IM-QTOF-MS – A new hyphenated separation technique for the analysis of complex samples |
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The four separation dimensions of 2D-LC-IM-qTOF-MS as an optimal tool for non-target analysis |
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Ion Mobility Spectrometry as a Powerful Separation Dimension in LC-MS |
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Ion Mobility Spectrometry as a Powerful Separation Dimension in LC-MS |
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Ion Mobility Spectrometry as a Powerful Separation Dimension in LC-MS |
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Panel discussion with Christian Minz (Eurofins) and Dr. Alexander Schiffer (Sanofi-Aventis) |
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The four separation dimensions of 2D-LC-IM-qTOF-MS as an optimal tool for non-target analysis |
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2D-LC-IM-MS as the ultimate tool in non-targeted analysis |
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A forgotten two-dimensional liquid chromatography approach coupled to an ion mobility-mass spectrometer |
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Ion mobility spectroscopy as a new separation dimension in LC-MS |
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Ion mobility spectroscopy as a new separation dimension in LC-MS (Tutorial) |
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Personalized Medicine – or Metabolomics 2.0 |
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New atmospheric pressure ion sources for mass spectrometry |
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2D-LC in combination with IMS and qTOF-MS for next generation metabolome analysis |
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2D-LC in combination with IMS and qTOF-MS for next generation metabolome analysis |
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Combination of the best of two worlds: LCxLC and IMS-QTOF-MS |
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Combination of the best of two worlds: LCxLC and IMS-QTOF-MS |
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Combination of the best of two worlds: LCxLC and IMS-QTOF-MS |
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Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook (part 1) Comprehensive two-dimensional liquid chromatography: Potential and Limitation (part 2) |
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Comprehensive two-dimensional liquid chromatography: Theory and applications |
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Combination of the best of two worlds: LCxLC and IMS-QTOF-MS |
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Combination of the best of two worlds: LCxLC and IMS-QTOF-MS |
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Combination of the best of two worlds: LCxLC and MS-QTOF-MS |
2012 - 2014
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Possible Quality control of modern and folk medicine |
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A novel ultra-sensitive GC-ion source for an Orbitrap-MS |
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Tutorial: Photo- and chemical ionization in atmospheric pressure mass spectrometry |
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Comprehensive two-dimensional Chromatography (GCxGC and LCxLC) for metabolom analysis |
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Product control of Chinese herbal medicine by comprehensive two-dimensional chromatography and novel ion sources |
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Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook |
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Comprehensive two-dimensional liquid chromatography: potential and limitations |
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How to find active agents in traditional folk medicine (Chinese Herbal Medicine) |
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Using of shift gradient in second dimension to improve the separation space in LCxLC |
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LCxLC with mixed-mode phases in the first dimension |
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Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook |
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Comprehensive two-dimensional liquid chromatography: potential and limitations |
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Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook |
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LCxLC analysis of Chinese Herbal Medicine |
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Comprehensive two-dimensional liquid chromatography: potential and limitations |
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Comprehensive two-dimensional liquid chromatography: potential and limitations |
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Quality control of Chinese Herbal Medicine with Comprehensive Two-Dimensional Chromatography and DIP-APCI-MS |
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Product control in traditional Chinese medicine: necessary and feasible? |
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Comprhensive two-dimensional liquid chromatography: potential and limitations |
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DIP-APCI: A new tool for product analysis |
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Quality control of Chinese Herbal Medicine with comprehensive two-dimensional chromatography and DIP-APCI-MS |
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DIP-APCI: A new ion source |
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Quality control of Chinese Herbal Medicine |
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Theory, benefits, limitations and potential of GCxGC |
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Comprehensive two-dimensional analytical methods and new ionization techniques |
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Analysis of Chinese Herbal Medicine (CHM) with Comprehensive Two-Dimensional Chromatography |
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Development and optimization of a DIP-APCI-ion source |
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The use of ionic liquid GC-columns in GCxGC-MS |
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The use of ionic liquid GC-columns in GCxGC-MS |
2009 - 2011
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Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook |
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Quantitative MALDI-(TOF)MS analysis of synthetic polymers and peptides |
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A simple method for the determination of peak capacity in comprehensive two-dimensional liquid chromatography |
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Analysis of organic compounds in complex matrices with comprehensive separation techniques and modified ion sources |
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Analysis of DNA adducts: Development of a high-performance analytical platform to meet the challenges in human health |
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Mass spectrometrical determination of biomarkers in complex matrices |
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What is the research group of Prof. Schmitz doing in Wuppertal? |
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Epigenetic determinations of cloned calfs and twins with MEKC-LIF |
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Analysis of traditional chinese medicine with comprehensive separation techniques (LCxLC and GCxGC) |
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Analysis of traditional chinese medicine with comprehensive separation techniques (LCxLC and GCxGC) |
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Analysis of Radix Angelicea sinensis with chiral GCxGC-qMS and the influence of aristolochic acid on the methylation level in rats |
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Theory of multi-dimensional separation techniques |
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Research Topics in the Department of Analytical Chemistry at the University of Wuppertal |
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Analysis of TCMs and identification of new biological active drugs |
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A universal ionisation label for the APLI-(TOF)MS analysis of small molecules and polymers |
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A universal ionisation label for the APLI-(TOF)MS analysis of small molecules and polymers |
2005 - 2008
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A universal ionisation label for the APLI-(TOF)MS analysis of small molecules and polymers |
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Atmospheric-Pressure Laser Ionization (APLI): A novel ionization method for the ultra-sensitive determination of aromatic compounds |
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Use of APLI-MS and CE-LIF for processing actual analytical questions |
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Atmospheric-Pressure Laser Ionization (APLI): A novel ionization method for the ultra-sensitive determination of aromatic compounds |
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Novel methods for ultra-trace analyses: APLI-MS and CE-LIF |
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Novel methods for ultra-trace analyses: APLI-MS and CE-LIF |
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Determination of the genome-wide DNA-methylation level with capillary electrophoresis |
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Determination of epigenetic changes (DNA-methylation level) at chemical carcinogenesis by CE-LIF |
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Ultra-sensitive determination of polycyclic aromatic compounds with atmospheric-pressure laser ionization (APLI) as an interface for GC-MS |
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Ultra-sensitive determination of polycyclic aromatic compounds with atmospheric-pressure laser ionization (APLI) as an interface for LC and GC-MS |
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Atmospheric-Pressure Laser Ionization (APLI) - A novel ionization method for coupling LC and GC with mass spectroscopy |
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Determination of epigenetic changes (DNA-methylation level) at chemical carcinogenesis by CE-LIF |
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Determination of the DNA-methylation level with CE-LIF |
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Atmospheric-Pressure Laserionization (APLI): A novel ionization method for trace analysis of lipophilic aromatic compounds |
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Determination of the DNA methylation level with capillary electrophoresis and laser-induced fluorescence detection (CE-LIF) |
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Atmospheric-Pressure Laserionization (APLI): A novel ionization method for trace analysis of lipophilic aromatic compounds |
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Analysis and molecular cancer epidemiology |
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Novel methods for ultra-trace analysis: APLI-MS, GCxGC, CE-LIF |
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Atmospheric-Pressure Laser Ionization (APLI): Mass spectrometric methods for the determination of aromatic hydrocarbons |
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Determination of the DNA-Methylation level by Capillary Electrophoresis |
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Atmospheric-Pressure Laser-Ionization (APLI) Mass Spectrometry for Determination of Aromatic Hydrocarbons |
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Panel discussion: Bachelor/Master = A successful structure for the following generation of chemists? |
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Atmospheric-Pressure Laser Ionization: A novel ionization method for LC-MS |
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Analysis of endogenous DNA-damages in mitochondrial and genomic DNA by ultra-sensitive fluorescence spectroscopy |
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CE-LIF analysis of endogenous damage in mitochondrial and genomic DNA |
2000 - 2004
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Comprehensive Two-Dimensional Gas Chromatography of Polycyclic Aromatic Hydrocarbons in Olive Oil |
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DNA adduct analysis and determination of the methylation level with capillary electrophoresis and LIF |
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Determination of carcinogens in complex matrices by comprehensive two-dimensional gas chromatography |
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Analysis of DNA-adducts, apurinic sites and 5-methylcytosines by CE-LIF |
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CE-LIF - A useful tool for the investigation of molecular and metabolic mechanisms of cancerogenesis |
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Determination of the Methylation level in tumor cells by capillary electrophoresis and laser-induced fluorescence detection |
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Determination of DNA-adducts as biomarkers of chemical carcinogenesis by capillary electrophoresis |
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Methods for the determination of biomarkers of chemical carcinogenesis and oxidative stress |
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Determination of DNA-adducts as biomarkers of chemical carcinogenesis by capillary electrophoresis |
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Development of an analytical method for the determination of DNA-adducts by capillary electrophoresis |
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Determination of DNA-adducts as biomarkers of chemical carcinogenesis by CE-LIF |
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Use of capillary electrophoresis in modern analysis |
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Capillary electrophoresis in modern analysis ▪ Development of an automatic genotoxicity test by analysis of fluorescence-labelled DNA-adducts |
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Analysis of poly clonal antibodies by fluorescent labelling and cIEF with multi-laser-induced fluorescence detection |
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Development of an automatic genotoxicity test by analysis of fluorescent labeled DNA-adducts |
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Analysis of Fluorescent labeled DNA-Adducts by Micellar Electrokinetic Chromatography |
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Analysis of Fluorescent labeled DNA-Adducts by Micellar Electrokinetic Chromatography |
1995 - 1999
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Development of a fluorescence-based method to determine DNA-adducts by capillary electrophoresis |
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Postlabeling and Capillary Electrophoresis |
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Analyse von Lipidhydroperoxiden mit HPLC und CE |