Faculty of Biology
Register of People
The person's links lead to the central register of persons of the UDE, refering to the data of LSF. Personal data can be edited in LSF (Login with Uni-ID is required).
Fakultät Biologie
Address
Universitätsstr 2
45117 Essen
45117 Essen
Room
S05 R02 H87
Phone
Fax
E-Mail
Functions
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
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Professor/in, Molekulare Genetik II
Current lectures
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2024 SS
Past lectures (max. 10)
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2023 WS
- Übungen zur Genetik (BSc Biologie, BSc Molekularbiologie, BSc AquaBio)
- Übungen zur Mikrobiologie und Genetik für medizinische Biologen
- Molekulare Genetik f. Molbio (VO u. PR)
- Seminar zur Genetik
- Allgemeine Methoden (Bachelor Bio)
- Einführung in die Genetik
- Allgemeine Methoden in der Molekularbiologie
- Group Meeting
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2023 SS
The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.
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TopBP1 utilises a bipartite GINS binding mode to support genome replicationIn: Nature Communications Vol. 15 (2024) Nr. 1, 1797Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
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Cell-type specificity of the human mutation landscape with respect to DNA replication dynamicsIn: Cell Genomics Vol. 3 (2023) Nr. 6, 100315Online Full Text: dx.doi.org/ (Open Access)
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Refining the domain architecture model of the replication origin firing factor Treslin/TICRRIn: Life Science Alliance Vol. 5 (2022) Nr. 5, e202101088Online Full Text: dx.doi.org/ (Open Access)
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The Role of MTBP as a Replication Origin Firing FactorIn: Biology Vol. 11 (2022) Nr. 6, 827Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transitionIn: Molecular Cell Vol. 82 (2022) Nr. 18, pp. 3350 - 3365.e7Online Full Text: dx.doi.org/ (Open Access)
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MTBP phosphorylation controls DNA replication origin firingIn: Scientific Reports Vol. 11 (2021) Nr. 1, 4242Online Full Text: dx.doi.org/ (Open Access)
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Origin firing regulations to control genome replication timingIn: Genes Vol. 10 (2019) Nr. 3, pp. 199Online Full Text: dx.doi.org/ (Open Access)
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The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7In: PLoS Biology Vol. 17 (2019) Nr. 1, e2006767Online Full Text: dx.doi.org/ (Open Access)
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BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligandsIn: eLife Vol. 7 (2018) pp. e39979Online Full Text: dx.doi.org/ (Open Access)
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Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resectionIn: eLife (2017) Nr. 6, pp. e21687Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Identification of a Heteromeric Complex That Promotes DNA Replication Origin Firing in Human CellsIn: Science Vol. 340 (2013) Nr. 6135, pp. 981 - 984Online Full Text: dx.doi.org/
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Activation of the replicative DNA helicase : breaking up is hard to doIn: Current Opinion in Cell Biology Vol. 24 (2012) Nr. 3, pp. 423 - 430Online Full Text: dx.doi.org/
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Cleavage of cohesin rings coordinates the separation of centrioles and chromatidsIn: Nature Cell Biology Vol. 13 (2011) Nr. 8, pp. 966 - 972Online Full Text: dx.doi.org/
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Regulation of DNA Replication through Sld3-Dpb11 Interaction Is Conserved from Yeast to HumansIn: Current Biology Vol. 21 (2011) Nr. 13, pp. 1152 - 1157Online Full Text: dx.doi.org/
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Phosphorylation-dependent Binding of Cyclin B1 to a Cdc6-like Domain of Human SeparaseIn: The Journal of Biological Chemistry (JBC) Vol. 283 (2008) Nr. 2, pp. 816 - 823Online Full Text: dx.doi.org/
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Anaphase Topsy-Turvy : Cdk1 a Securin, Separase a CKIIn: Cell Cycle Vol. 5 (2006) Nr. 1, pp. 11 - 13Online Full Text: dx.doi.org/
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Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytesIn: Nature Cell Biology Vol. 8 (2006) Nr. 9, pp. 1035 - 1037Online Full Text: dx.doi.org/
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Mutual inhibition of separase and Cdk1 by two-step complex formationIn: Molecular Cell Vol. 19 (2005) Nr. 1, pp. 135 - 141Online Full Text: dx.doi.org/ (Open Access)
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Rephrasing anaphase : separase FEARs shugoshinIn: Chromosoma Vol. 113 (2005) Nr. 8, pp. 409 - 417Online Full Text: dx.doi.org/
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Regulation of the Initiation of DNA Replication upon DNA Damage in EukaryotesIn: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Eds.) 2016, pp. 443 - 460Online Full Text: dx.doi.org/
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Roles of Sld2, Sld3, and Dpb11 in Replication InitiationIn: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Eds.) 2016, pp. 297 - 318Online Full Text: dx.doi.org/