Faculty of Biology

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Prof. Dr. Dominik Boos

Fakultät Biologie

Address
Universitätsstr 2
45117 Essen
Room
S05 R02 H87
Phone
+49 201 183 4132
Fax
+49 201 183 4397
E-Mail
dominik.boos@uni-due.de
Website
https://www.uni-due.de/zmb/molecular-genetics-boos/index.php

Functions

  • Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie

  • Professor/in, Molekulare Genetik II

The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.

    Journal articles

  • Day, Matthew; Tetik, Bilal; Parlak, Milena; Almeida-Hernández, Yasser; Räschle, Markus; Kaschani, Farnusch; Siegert, Heike; Marko, Anika; Sanchez-Garcia, Elsa; Kaiser, Markus; Barker, Isabel A.; Pearl, Laurence H.; Oliver, Antony W.; Boos, Dominik
    TopBP1 utilises a bipartite GINS binding mode to support genome replication
    In: Nature Communications, Vol. 15, 2024, Nr. 1, 1797
    DOI, Online Full Text (Open Access)
  • Caballero, Madison; Boos, Dominik; Koren, Amnon
    Cell-type specificity of the human mutation landscape with respect to DNA replication dynamics
    In: Cell Genomics, Vol. 3, 2023, Nr. 6, 100315
    DOI (Open Access)
  • Ferreira, Pedro; Sanchez-Pulido, Luis; Marko, Anika; Ponting, Chris P.; Boos, Dominik
    Refining the domain architecture model of the replication origin firing factor Treslin/TICRR
    In: Life Science Alliance, Vol. 5, 2022, Nr. 5, e202101088
    DOI (Open Access)
  • Zaffar, Eman; Ferreira, Pedro; Sanchez-Pulido, Luis; Boos, Dominik
    The Role of MTBP as a Replication Origin Firing Factor
    In: Biology, Vol. 11, 2022, Nr. 6, 827
    DOI, Online Full Text (Open Access)
  • Zonderland, Gijs; Vanzo, Riccardo; Amitash, Sampath; Martín-Doncel, Elena; Coscia, Fabian; Mund, Andreas; Lerdrup, Mads; Benada, Jan; Boos, Dominik; Toledo, Luis
    The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition
    In: Molecular Cell, Vol. 82, 2022, Nr. 18, pp. 3350 – 3365.e7
    DOI (Open Access)
  • Ferreira, Pedro; Höfer, Verena; Kronshage, Nora; Marko, Anika; Reusswig, Karl-Uwe; Tetik, Bilal; Dießel, Christoph; Köhler, Kerstin; Tschernoster, Nikolai; Altmüller, Janine; Schulze, Nina; Pfander, Boris; Boos, Dominik
    MTBP phosphorylation controls DNA replication origin firing
    In: Scientific Reports, Vol. 11, 2021, Nr. 1, 4242
    DOI, Online Full Text (Open Access)
  • Boos, Dominik; Ferreira, Pedro
    Origin firing regulations to control genome replication timing
    In: Genes, Vol. 10, 2019, Nr. 3, 199
    DOI (Open Access)
  • Köhler, Kerstin; Sanchez-Pulido, Luis; Höfer, Verena; Marko, Anika; Ponting, Chris P.; Snijders, Ambrosius P.; Feederle, Regina; Schepers, Aloys; Boos, Dominik
    The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7
    In: PLoS Biology, Vol. 17, 2019, Nr. 1, e2006767
    DOI (Open Access)
  • Day, Matthew; Rappas, Mathieu; Ptasinska, Katie; Boos, Dominik; Oliver, Antony W.; Pearl, Laurence H.
    BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands
    In: eLife, Vol. 7, 2018, e39979
    DOI (Open Access)
  • Bantele, Susanne; Pfander, Dominik; Boos, Dominik; Ferreira, Pedro; Gritenaite, Dalia
    Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection
    In: eLife, 2017, Nr. 6, e21687
    DOI, Online Full Text (Open Access)
  • Boos, Dominik; Diffley, John F. X.; Yekezare, Mona
    Identification of a Heteromeric Complex That Promotes DNA Replication Origin Firing in Human Cells
    In: Science, Vol. 340, 2013, Nr. 6135, pp. 981 – 984
    DOI
  • Boos, Dominik; Diffley, John FX; Frigola, Jordi
    Activation of the replicative DNA helicase : breaking up is hard to do
    In: Current Opinion in Cell Biology, Vol. 24, 2012, Nr. 3, pp. 423 – 430
    DOI
  • Schöckel, Laura; Stemmann, Olaf; Boos, Dominik; Mayer, Bernd; Möckel, Martin
    Cleavage of cohesin rings coordinates the separation of centrioles and chromatids
    In: Nature Cell Biology, Vol. 13, 2011, Nr. 8, pp. 966 – 972
    DOI
  • Boos, Dominik; Ponting, Chris P.; Oliver, Antony W.; Pearl, Laurence H.; Rappas, Mathieu; Sanchez-Pulido, Luis
    Regulation of DNA Replication through Sld3-Dpb11 Interaction Is Conserved from Yeast to Humans
    In: Current Biology, Vol. 21, 2011, Nr. 13, pp. 1152 – 1157
    DOI
  • Boos, Dominik; Stemmann, Olaf; Kuffer, Christian; Lenobel, Rene
    Phosphorylation-dependent Binding of Cyclin B1 to a Cdc6-like Domain of Human Separase
    In: The Journal of Biological Chemistry (JBC), Vol. 283, 2008, Nr. 2, pp. 816 – 823
    DOI
  • Stemmann, Olaf; Boos, Dominik; Gorr, Ingo H.
    Anaphase Topsy-Turvy : Cdk1 a Securin, Separase a CKI
    In: Cell Cycle, Vol. 5, 2006, Nr. 1, pp. 11 – 13
    DOI
  • Gorr, Ingo H.; Stemmann, Olaf; Wühr, Martin; Boos, Dominik; Reis, Alexandra
    Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytes
    In: Nature Cell Biology, Vol. 8, 2006, Nr. 9, pp. 1035 – 1037
    DOI
  • Gorr, Ingo H.; Boos, Dominik; Stemmann, Olaf
    Mutual inhibition of separase and Cdk1 by two-step complex formation
    In: Molecular Cell, Vol. 19, 2005, Nr. 1, pp. 135 – 141
    DOI (Open Access)
  • Stemmann, Olaf; Boos, Dominik; Gorr, Ingo H.
    Rephrasing anaphase : separase FEARs shugoshin
    In: Chromosoma, Vol. 113, 2005, Nr. 8, pp. 409 – 417
    DOI

    • Preprints

  • Zaffar, Eman; Vieyto-Nuñez, Julio; Pravi, Katerina; Aslam, Mohammed Faidh; Almeida-Hernández, Yasser; Mieres-Pérez, Joel; Kaschani, Farnusch; Kaiser, Markus; Kroesen, Anika; Boos, Dominik; Sánchez-García, Elsa
    MTBP allosterically activates Cdk8-CycC kinase activity
    2025
    DOI (Open Access)

    • Book articles / Proceedings papers

  • Köhler, Kerstin; Pfander, Boris; Ferreira, Pedro; Boos, Dominik
    Regulation of the Initiation of DNA Replication upon DNA Damage in Eukaryotes
    In: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Eds.). Cham: Springer, 2016, pp. 443 – 460
    DOI
  • Reußwig, Karl-Uwe; Pfander, Boris; Boos, Dominik
    Roles of Sld2, Sld3, and Dpb11 in Replication Initiation
    In: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Eds.). Cham: Springer, 2016, pp. 297 – 318
    DOI