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Fakultät Biologie
Anschrift
Universitätsstr 2
45117 Essen
45117 Essen
Raum
S05 R02 H87
Telefon
Telefax
E-Mail
Funktionen
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
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Professor/in, Molekulare Genetik II
Aktuelle Veranstaltungen
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SoSe 2025
Vergangene Veranstaltungen (max. 10)
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WiSe 2024
- Übungen zur Genetik (BSc Biologie, BSc Molekularbiologie, BSc AquaBio)
- Allgemeine Methoden in der Molekularbiologie
- Übungen zur Mikrobiologie und Genetik für medizinische Biologen
- Allgemeine Methoden (Bachelor Bio)
- Seminar zur Genetik
- Group Meeting
- Einführung in die Genetik
- Molekulare Genetik f. Molbio (VO u. PR)
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SoSe 2024
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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TopBP1 utilises a bipartite GINS binding mode to support genome replicationIn: Nature Communications , Jg. 15 2024, Nr. 1, 1797DOI, Online Volltext (Open Access)
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Cell-type specificity of the human mutation landscape with respect to DNA replication dynamicsIn: Cell Genomics , Jg. 3 2023, Nr. 6, 100315DOI (Open Access)
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Refining the domain architecture model of the replication origin firing factor Treslin/TICRRIn: Life Science Alliance , Jg. 5 2022, Nr. 5, e202101088DOI (Open Access)
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The Role of MTBP as a Replication Origin Firing FactorIn: Biology , Jg. 11 2022, Nr. 6, 827DOI, Online Volltext (Open Access)
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The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transitionIn: Molecular Cell , Jg. 82 2022, Nr. 18, S. 3350 – 3365.e7DOI (Open Access)
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MTBP phosphorylation controls DNA replication origin firingIn: Scientific Reports , Jg. 11 2021, Nr. 1, 4242DOI, Online Volltext (Open Access)
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Origin firing regulations to control genome replication timingIn: Genes , Jg. 10 2019, Nr. 3, 199DOI (Open Access)
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The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7In: PLoS Biology , Jg. 17 2019, Nr. 1, e2006767DOI (Open Access)
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BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligandsIn: eLife , Jg. 7 2018, e39979DOI (Open Access)
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Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resectionIn: eLife 2017, Nr. 6, e21687DOI (Open Access)
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Identification of a Heteromeric Complex That Promotes DNA Replication Origin Firing in Human CellsIn: Science , Jg. 340 2013, Nr. 6135, S. 981 – 984
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Activation of the replicative DNA helicase : breaking up is hard to doIn: Current Opinion in Cell Biology , Jg. 24 2012, Nr. 3, S. 423 – 430
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Cleavage of cohesin rings coordinates the separation of centrioles and chromatidsIn: Nature Cell Biology , Jg. 13 2011, Nr. 8, S. 966 – 972
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Regulation of DNA Replication through Sld3-Dpb11 Interaction Is Conserved from Yeast to HumansIn: Current Biology , Jg. 21 2011, Nr. 13, S. 1152 – 1157
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Phosphorylation-dependent Binding of Cyclin B1 to a Cdc6-like Domain of Human SeparaseIn: The Journal of Biological Chemistry (JBC) , Jg. 283 2008, Nr. 2, S. 816 – 823
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Anaphase Topsy-Turvy : Cdk1 a Securin, Separase a CKIIn: Cell Cycle , Jg. 5 2006, Nr. 1, S. 11 – 13
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Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytesIn: Nature Cell Biology , Jg. 8 2006, Nr. 9, S. 1035 – 1037
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Mutual inhibition of separase and Cdk1 by two-step complex formationIn: Molecular Cell , Jg. 19 2005, Nr. 1, S. 135 – 141DOI (Open Access)
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Rephrasing anaphase : separase FEARs shugoshinIn: Chromosoma , Jg. 113 2005, Nr. 8, S. 409 – 417
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Regulation of the Initiation of DNA Replication upon DNA Damage in EukaryotesIn: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Hrsg.) 2016, S. 443 – 460
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Roles of Sld2, Sld3, and Dpb11 in Replication InitiationIn: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Hrsg.) 2016, S. 297 – 318