Faculty of Biology
Register of People
The person's links lead to the central register of persons of the UDE, refering to the data of LSF. Personal data can be edited in LSF (Login with Uni-ID is required).
Address
Universitätsstr. 2-5
45141 Essen
45141 Essen
Room
S03 S00 A35
Phone
E-Mail
Website
Functions
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Wiss. Mitarbeiterinnen/Mitarbeiter, Strukturelle und Medizinische Biochemie
Current lectures
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WiSe 2025
- StrukturBio-Praktikum
- Praktikum allgemeine Methoden
- VO Struktur und Funktion von Biopolymeren
- StrukturBio-Praktikum
- Struktur und Funktion der Zelle (LA Ba)
- Biophysikalische Chemie
- Analytikmethoden zur Struktur von Molekülen
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Physik für Biologen (Bio B.Sc. und Aquatische Bio B.Sc., Molekularbiologie)
- MedBio Lab Rotation
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
- StrukturBio-Praktikum
Past lectures (max. 10)
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SoSe 2025
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WiSe 2024
- MedBio Lab Rotation
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Struktur und Funktion der Zelle (LA Ba)
- Analytikmethoden zur Struktur von Molekülen
- Physik für Biologen (Bio B.Sc. und Aquatische Bio B.Sc., Molekularbiologie)
- VO Struktur und Funktion von Biopolymeren
- Biophysikalische Chemie
The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.
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Highly Preorganized Calixarene Tweezers for Protein Recognition.In: Biomacromolecules, Vol. 26, 2025, Nr. 8, pp. 5310 – 5319
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Molecular Tweezers Block the Functional Pore of a Protein MachineIn: Journal of the American Chemical Society: JACS, Vol. 147, 2025, Nr. 20, pp. 16836 – 16849DOI (Open Access)
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Molecular Tweezers with Built-in Photoswitches Modulate Protein ActivityIn: RSC Chemical Biology, 2025, in pressDOI (Open Access)
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Photoresponsive molecular tweezers modulate Taspase 1 activityIn: RSC Chemical Biology, 2025, in pressDOI (Open Access)
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Synthesis and characterization of dodecylamine-capped ultrasmall metallic palladium nanoparticles (2 nm)In: Nanoscale Advances, 2025, in pressDOI (Open Access)
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Synthesis and characterization of ultrasmall rhenium nanoparticles (1.5 nm)In: Journal of Nanoparticle Research, Vol. 27, 2025, Nr. 8, 218DOI (Open Access)
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Temperature‐Resolved Fluorescence Quenching on Ultrasmall Gold Nanoparticles Conjugated with Dye‐Labeled PeptidesIn: Nano Select, 2025, in pressDOI (Open Access)
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The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain AllosteryIn: Proteins: Structure, Function and Genetics, Vol. 93, 2025, Nr. 9, pp. 1481 – 1497DOI (Open Access)
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Ultrasmall Gold Nanoparticles (2 nm) Decorated with a High Density of Photochemically Switchable LigandsIn: Chemistry - A European Journal, 2025DOI (Open Access)
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Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1In: Chemistry - A European Journal, Vol. 30, 2024, Nr. 56, e202401542DOI (Open Access)
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High resolution analysis of proteolytic substrate processingIn: The Journal of Biological Chemistry (JBC), Vol. 300, 2024, Nr. 11, 107812DOI, Online Full Text (Open Access)
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Increased Cytotoxicity of Bimetallic Ultrasmall Silver–Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same SizeIn: Materials, Vol. 17, 2024, Nr. 15, 3702DOI (Open Access)
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Possibilities and limitations of solution-state NMR spectroscopy to analyze the ligand shell of ultrasmall metal nanoparticlesIn: Nanoscale Advances, Vol. 6, 2024, Nr. 13, pp. 3285 – 3298DOI (Open Access)
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Rational correction of pathogenic conformational defects in HTRA1In: Nature Communications, Vol. 15, 2024, Nr. 1, 5944DOI (Open Access)
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The Molecular Footprint of Peptides on the Surface of Ultrasmall Gold Nanoparticles (2 nm) Is Governed by Steric DemandIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Vol. 128, 2024, Nr. 17, pp. 4266 – 4281
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Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with MicrotubulesIn: Journal of the American Chemical Society: JACS, Vol. 145, 2023, Nr. 28, pp. 15251 – 15264
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Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules, Vol. 24, 2023, Nr. 8, pp. 3666 – 3679
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The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseIn: Nature Communications, Vol. 14, 2023, Nr. 1, 3258DOI, Online Full Text (Open Access)
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Ultrastructure and Surface Composition of Glutathione-Terminated Ultrasmall Silver, Gold, Platinum, and Alloyed Silver-Platinum Nanoparticles (2 nm)In: Inorganic Chemistry, Vol. 62, 2023, Nr. 42, pp. 17470 – 17485
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances, Vol. 12, 2022, Nr. 53, pp. 34176 – 34184DOI (Open Access)
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Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules, Vol. 23, 2022, Nr. 11, pp. 4504 – 4518
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Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)In: Inorganic Chemistry, Vol. 61, 2022, Nr. 12, pp. 5133 – 5147
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Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Vol. 125, 2021, Nr. 21, pp. 5645 – 5659
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New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Vol. 125, 2021, Nr. 1, pp. 115 – 127DOI (Open Access)
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Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein TargetingIn: ACS Applied Bio Materials, Vol. 4, 2021, Nr. 1, pp. 945 – 965DOI (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications, Vol. 12, 2021, Nr. 1, pp. 1505DOI, Online Full Text (Open Access)
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Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRafIn: ChemBioChem, Vol. 22, 2021, Nr. 8, pp. 1456 – 1463DOI (Open Access)
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Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition, Vol. 59, 2020, Nr. 14, pp. 5567 – 5571DOI (Open Access)
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NMR Spectroscopy of supramolecular chemistry on protein surfacesIn: Beilstein Journal of Organic Chemistry, Vol. 16, 2020, pp. 2505 – 2522DOI (Open Access)
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Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopyIn: Langmuir, Vol. 35, 2019, Nr. 22, pp. 7191 – 7204
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Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein InteractionsIn: ChemBioChem, Vol. 20, 2019, Nr. 23, pp. 2921 – 2926
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Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)In: Langmuir, Vol. 35, 2019, Nr. 3, pp. 767 – 778
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Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPaseIn: Biomolecules, Vol. 9, 2019, Nr. 12, 876DOI, Online Full Text (Open Access)
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An NMR Method To Pinpoint Supramolecular Ligand Binding to Basic Residues on ProteinsIn: Angewandte Chemie International Edition, Vol. 56, 2017, Nr. 46, pp. 14758 – 14762
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Molecular tweezers target a protein-protein interface and thereby modulate complex formationIn: Chemical Communications: ChemComm, Vol. 52, 2016, Nr. 98, pp. 14141 – 14144DOI (Open Access)
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Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1In: PLoS ONE, Vol. 11, 2016, Nr. 3, pp. e0151431DOI, Online Full Text (Open Access)
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The acidic domain is a unique structural feature of the splicing factor SYNCRIPIn: Protein Science, Vol. 25, 2016, Nr. 8, pp. 1545 – 1550DOI (Open Access)
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Reversibly locked thionucleobase pairs in DNA to study base flipping enzymesIn: Beilstein Journal of Organic Chemistry, Vol. 10, 2014, pp. 2293 – 2306DOI (Open Access)