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Dr. Christine Beuck

Anschrift
Universitätsstr. 2-5
45141 Essen
Raum
S03 S00 A35
Telefon
0201 183 2929
E-Mail
christine.beuck@uni-due.de
Webseite
http://www.uni-due.de/biochemie

Funktionen

  • Wiss. Mitarbeiterinnen/Mitarbeiter, Strukturelle und Medizinische Biochemie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Hommel, Katrin; Theisen, Sebastian; Blueggel, Mike; Niemeyer, Felix C.; Beuck, Christine; Bayer, Peter; Zadmard, Reza; Schrader, Thomas; Knauer, Shirley K.
    Highly Preorganized Calixarene Tweezers for Protein Recognition.
    In: Biomacromolecules, Jg. 26, 2025, Nr. 8, S. 5310 – 5319
    DOI
  • Kirupakaran, Abbna; van den Boom, Johannes; Blueggel, Mike; Beuck, Christine; Niemeyer, Felix; Hayduk, Matthias; Balszuweit, Jan; Bayer, Peter; Voskuhl, Jens; Meyer, Hemmo; Schrader, Thomas
    Molecular Tweezers Block the Functional Pore of a Protein Machine
    In: Journal of the American Chemical Society: JACS, Jg. 147, 2025, Nr. 20, S. 16836 – 16849
    DOI (Open Access)
  • Bietti, Antonio; Kauth, Alisa-Maite; Hommel, Katrin; Blüggel, Mike; Mohr, Laurenz; Niemeyer, Felix; Beuck, Christine; Bayer, Peter; Knauer, Shirley; Ravoo, Bart Jan; Schrader, Thomas
    Molecular Tweezers with Built-in Photoswitches Modulate Protein Activity
    In: RSC Chemical Biology, 2025, in press
    DOI (Open Access)
  • Bietti, Antonio L. Figueroa; Kauth, Alisa-Maite A.; Hommel, Katrin; Blueggel, Mike; Mohr, Laurenz; Niemeyer, Felix C.; Beuck, Christine; Bayer, Peter; Knauer, Shirley K.; Jan Ravoo, Bart; Schrader, Thomas
    Photoresponsive molecular tweezers modulate Taspase 1 activity
    In: RSC Chemical Biology, 2025, in press
    DOI (Open Access)
  • Kost, Niklas; Prymak, Oleg; Loza, Kateryna; Beuck, Christine; Bayer, Peter; Weidenthaler, Claudia; Heggen, Marc; Oliveira, Cristiano L. P.; Epple, Matthias
    Synthesis and characterization of dodecylamine-capped ultrasmall metallic palladium nanoparticles (2 nm)
    In: Nanoscale Advances, 2025, in press
    DOI (Open Access)
  • Kost, Niklas; Prymak, Oleg; Loza, Kateryna; Heggen, Marc; Oliveira, Cristiano L. P.; Beuck, Christine; Bayer, Peter; Epple, Matthias
    Synthesis and characterization of ultrasmall rhenium nanoparticles (1.5 nm)
    In: Journal of Nanoparticle Research, Jg. 27, 2025, Nr. 8, 218
    DOI (Open Access)
  • Wagner, Lisa-Sofie; Huber, Alexander; Loza, Kateryna; Beuck, Christine; Heggen, Marc; Bayer, Peter; Voskuhl, Jens; Epple, Matthias
    Temperature‐Resolved Fluorescence Quenching on Ultrasmall Gold Nanoparticles Conjugated with Dye‐Labeled Peptides
    In: Nano Select, 2025, in press
    DOI (Open Access)
  • Sternberg, Anna; Borger, Jennifer Lynne; Thies, Mathilda; Matena, Anja; Blüggel, Mike; Kamba, Bianca; Beuck, Christine; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter
    The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain Allostery
    In: Proteins: Structure, Function and Genetics, Jg. 93, 2025, Nr. 9, S. 1481 – 1497
    DOI (Open Access)
  • Wagner, Lisa-Sofie; Thiele, Tobias; Loza, Kateryna; Beuck, Christine; Bayer, Peter; Heggen, Marc; Giese, Michael R. A.; Epple, Matthias
    Ultrasmall Gold Nanoparticles (2 nm) Decorated with a High Density of Photochemically Switchable Ligands
    In: Chemistry - A European Journal, 2025
    DOI (Open Access)
  • Hommel, Katrin; Kauth, Alisa-Maite A.; Kirupakaran, Abbna; Theisen, Sebastian; Hayduk, Matthias; Niemeyer, Felix C.; Beuck, Christine; Zadmard, Reza; Bayer, Peter; Jan Ravoo, Bart; Voskuhl, Jens; Schrader, Thomas; Knauer, Shirley K.
    Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1
    In: Chemistry - A European Journal, Jg. 30, 2024, Nr. 56, e202401542
    DOI (Open Access)
  • Schillinger, Jasmin; Koci, Michelle; Bravo-Rodriguez, Kenny; Heilmann, Geronimo; Kaschani, Farnusch; Kaiser, Markus; Beuck, Christine; Luecke, Hartmut; Huber, Robert; Hellerschmied-Jelinek, Doris; Burston, Steven G.; Ehrmann, Michael
    High resolution analysis of proteolytic substrate processing
    In: The Journal of Biological Chemistry (JBC), Jg. 300, 2024, Nr. 11, 107812
    DOI, Online Volltext (Open Access)
  • Wolff, Natalie; Białas, Nataniel; Loza, Kateryna; Heggen, Marc; Schaller, Torsten; Niemeyer, Felix; Weidenthaler, Claudia; Beuck, Christine; Bayer, Peter; Prymak, Oleg; Oliveira, Cristiano L. P.; Epple, Matthias
    Increased Cytotoxicity of Bimetallic Ultrasmall Silver–Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same Size
    In: Materials, Jg. 17, 2024, Nr. 15, 3702
    DOI (Open Access)
  • Wolff, Natalie; Beuck, Christine; Schaller, Torsten; Epple, Matthias
    Possibilities and limitations of solution-state NMR spectroscopy to analyze the ligand shell of ultrasmall metal nanoparticles
    In: Nanoscale Advances, Jg. 6, 2024, Nr. 13, S. 3285 – 3298
    DOI (Open Access)
  • Beaufort, Nathalie; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree; Podlesainski, David; Richter, Tim; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G.; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo Rodriguez, Kenny; Mieres-Perez, Joel; Beuck, Christine; Uebel, Stephan; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer; Todorov-Völgyi, Katalin; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt; Müller, Stephan A.; Wurst, Wolfgang; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu; Clausen, Tim; Huber, Robert; Lichtenthaler, Stefan F.; Schmuck, Carsten; Giese, Michael; Kaiser, Markus; Ehrmann, Michael; Dichgans, Martin
    Rational correction of pathogenic conformational defects in HTRA1
    In: Nature Communications, Jg. 15, 2024, Nr. 1, 5944
    DOI (Open Access)
  • Wagner, Lisa-Sofie; Prymak, Oleg; Schaller, Torsten; Beuck, Christine; Loza, Kateryna; Niemeyer, Felix; Gumbiowski, Nina; Kostka, Kathrin; Bayer, Peter; Heggen, Marc; Oliveira, Cristiano L. P.; Epple, Matthias
    The Molecular Footprint of Peptides on the Surface of Ultrasmall Gold Nanoparticles (2 nm) Is Governed by Steric Demand
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Jg. 128, 2024, Nr. 17, S. 4266 – 4281
    DOI
  • Neblik, Jonas; Kirupakaran, Abbna; Beuck, Christine; Mieres-Perez, Joel; Niemeyer, Felix; Le, My-Hue; Telgheder, Ursula; Schmuck, Jessica Felice; Dudziak, Alexander; Bayer, Peter; Sanchez-Garcia, Elsa; Westermann, Stefan; Schrader, Thomas
    Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with Microtubules
    In: Journal of the American Chemical Society: JACS, Jg. 145, 2023, Nr. 28, S. 15251 – 15264
    DOI
  • Seiler, Theresa; Lennartz, Annika; Klein, Kai; Hommel, Katrin; Figueroa Bietti, Antonio; Hadrovic, Inesa; Kollenda, Sebastian; Sager, Jonas; Beuck, Christine; Chlosta, Emilia; Bayer, Peter; Juul-Madsen, Kristian; Vorup-Jensen, Thomas; Schrader, Thomas; Epple, Matthias; Knauer, Shirley; Hartmann, Laura
    Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on Nanoparticles
    In: Biomacromolecules, Jg. 24, 2023, Nr. 8, S. 3666 – 3679
    DOI
  • Blüggel, Mike; Kröning, Alexander; Kracht, Matthias; van den Boom, Johannes; Dabisch, Matthias; Göhring, Anna; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter; Meyer, Hemmo; Beuck, Christine
    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
    In: Nature Communications, Jg. 14, 2023, Nr. 1, 3258
    DOI, Online Volltext (Open Access)
  • Wolff, Natalie; Loza, Kateryna; Heggen, Marc; Schaller, Torsten; Niemeyer, Felix; Bayer, Peter; Beuck, Christine; Oliveira, Cristiano L P; Prymak, Oleg; Weidenthaler, Claudia; Epple, Matthias
    Ultrastructure and Surface Composition of Glutathione-Terminated Ultrasmall Silver, Gold, Platinum, and Alloyed Silver-Platinum Nanoparticles (2 nm)
    In: Inorganic Chemistry, Jg. 62, 2023, Nr. 42, S. 17470 – 17485
    DOI
  • Höing, Alexander; Struth, Robin; Beuck, Christine; Rafieiolhosseini, Neda; Hoffmann, Daniel; Stauber, Roland H.; Bayer, Peter; Niemeyer, Jochen; Knauer, Shirley
    Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
    In: RSC Advances, Jg. 12, 2022, Nr. 53, S. 34176 – 34184
    DOI (Open Access)
  • Höing, Alexander; Kirupakaran, Abbna; Beuck, Christine; Pörschke, Marius; Niemeyer, Felix; Seiler, Theresa; Hartmann, Laura; Bayer, Peter; Schrader, Thomas; Knauer, Shirley
    Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular Tweezers
    In: Biomacromolecules, Jg. 23, 2022, Nr. 11, S. 4504 – 4518
    DOI
  • Wetzel, Oliver; Prymak, Oleg; Loza, Kateryna; Gumbiowski, Nina; Heggen, Marc; Bayer, Peter; Beuck, Christine; Weidenthaler, Claudia; Epple, Matthias
    Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)
    In: Inorganic Chemistry, Jg. 61, 2022, Nr. 12, S. 5133 – 5147
    DOI
  • Wetzel, Oliver; Hosseini, Shabnam; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Bayer, Peter; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Weidenthaler, Claudia; Epple, Matthias
    Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Jg. 125, 2021, Nr. 21, S. 5645 – 5659
    DOI
  • van der Meer, Selina Beatrice; Hadrovic, Inesa; Meiners, Annika; Loza, Kateryna; Heggen, Marc; Knauer, Shirley; Bayer, Peter; Schrader, Thomas; Beuck, Christine; Epple, Matthias
    New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid binders
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Jg. 125, 2021, Nr. 1, S. 115 – 127
    DOI (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Sehnem, Andre Luiz; Oliveira, Cristiano L. P.; Bayer, Peter; Beuck, Christine; Epple, Matthias
    Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein Targeting
    In: ACS Applied Bio Materials, Jg. 4, 2021, Nr. 1, S. 945 – 965
    DOI (Open Access)
  • Meiners, Annika; Bäcker, Sandra; Hadrovic, Inesa; Heid, Christian; Beuck, Christine; Ruiz-Blanco, Yasser B.; Mieres-Perez, Joel; Pörschke, Marius; Grad, Jean-Noël; Vallet, Cecilia; Hoffmann, Daniel; Bayer, Peter; Sánchez-García, Elsa; Schrader, Thomas; Knauer, Shirley
    Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezers
    In: Nature Communications, Jg. 12, 2021, Nr. 1, S. 1505
    DOI, Online Volltext (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Ottmann, Christian; Bayer, Peter; Beuck, Christine; Epple, Matthias
    Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRaf
    In: ChemBioChem, Jg. 22, 2021, Nr. 8, S. 1456 – 1463
    DOI (Open Access)
  • Vallet, Cecilia; Aschmann, Dennis; Beuck, Christine; Killa, Matthias; Meiners, Annika; Mertel, Marcel; Ehlers, Martin; Bayer, Peter; Schmuck, Carsten; Giese, Michael R. A.; Knauer, Shirley
    Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole Ligand
    In: Angewandte Chemie International Edition, Jg. 59, 2020, Nr. 14, S. 5567 – 5571
    DOI (Open Access)
  • Bayer, Peter; Matena, Anja; Beuck, Christine
    NMR Spectroscopy of supramolecular chemistry on protein surfaces
    In: Beilstein Journal of Organic Chemistry, Jg. 16, 2020, S. 2505 – 2522
    DOI (Open Access)
  • van der Meer, Selina; Loza, Kateryna; Wey, Karolin; Heggen, Marc; Beuck, Christine; Bayer, Peter; Epple, Matthias
    Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopy
    In: Langmuir, Jg. 35, 2019, Nr. 22, S. 7191 – 7204
    DOI
  • Bartsch, Lina; Bartel, Maria; Gigante, Alba; Iglesias-Fernández, Javier; Ruiz-Blanco, Yasser B.; Beuck, Christine; Briels, Jeroen; Tötsch, Niklas; Bayer, Peter; Sánchez-García, Elsa; Ottmann, Christian; Schmuck, Carsten
    Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein Interactions
    In: ChemBioChem, Jg. 20, 2019, Nr. 23, S. 2921 – 2926
    DOI
  • Ruks, Tatjana; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Zähres, Manfred; Loza, Kateryna; Heggen, Marc; Hagemann, Ulrich; Mayer, Christian; Bayer, Peter; Epple, Matthias
    Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)
    In: Langmuir, Jg. 35, 2019, Nr. 3, S. 767 – 778
    DOI
  • Blüggel, Mike; van den Boom, Johannes; Meyer, Hemmo; Bayer, Peter; Beuck, Christine
    Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase
    In: Biomolecules, Jg. 9, 2019, Nr. 12, 876
    DOI, Online Volltext (Open Access)
  • Hogeweg, Anna; Sowislok, Andrea; Schrader, Thomas; Beuck, Christine
    An NMR Method To Pinpoint Supramolecular Ligand Binding to Basic Residues on Proteins
    In: Angewandte Chemie International Edition, Jg. 56, 2017, Nr. 46, S. 14758 – 14762
    DOI
  • Trusch, Franziska; Kowski, Klaus; Bravo-Rodriguez, Kenny; Beuck, Christine; Sowislok, Andrea; Wettig, Burkhard; Matena, Anja; Sánchez-García, Elsa; Meyer, Hemmo; Schrader, Thomas; Bayer, Peter
    Molecular tweezers target a protein-protein interface and thereby modulate complex formation
    In: Chemical Communications: ChemComm, Jg. 52, 2016, Nr. 98, S. 14141 – 14144
    DOI (Open Access)
  • van den Boom, Johannes; Trusch, Franziska; Hoppstock, Lukas; Beuck, Christine; Bayer, Peter
    Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1
    In: PLoS ONE, Jg. 11, 2016, Nr. 3, S. e0151431
    DOI, Online Volltext (Open Access)
  • Beuck, Christine; Williamson, James R.; Wüthrich, Kurt; Serrano, Pedro
    The acidic domain is a unique structural feature of the splicing factor SYNCRIP
    In: Protein Science, Jg. 25, 2016, Nr. 8, S. 1545 – 1550
    DOI (Open Access)
  • Beuck, Christine; Weinhold, Elmar
    Reversibly locked thionucleobase pairs in DNA to study base flipping enzymes
    In: Beilstein Journal of Organic Chemistry, Jg. 10, 2014, S. 2293 – 2306
    DOI (Open Access)