Faculty of Biology
Register of People
The person's links lead to the central register of persons of the UDE, refering to the data of LSF. Personal data can be edited in LSF (Login with Uni-ID is required).
DKFZ-Abteilung für Translationale Neuroonkologie am WTZ - Universitätsklinikum Essen
E-Mail
Functions
-
Professorinnen/Professoren, Experimentelle Immunologie und Bildgebung
Current lectures
-
2024 SS
Past lectures (max. 10)
-
2023 SS
-
2022 SS
-
2021 SS
The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.
-
KDM5B predicts temozolomide-resistant subclones in glioblastomaIn: iScience Vol. 27 (2024) Nr. 1, 108596Online Full Text: dx.doi.org/ (Open Access)
-
The influence of radiological tumor growth pattern on sino‑nasal health in pituitary adenomasIn: Oncology Letters Vol. 27 (2024) Nr. 3, 125Online Full Text: dx.doi.org/ (Open Access)
-
Treatment Strategies for Glioblastoma in the Elderly : What Should We Focus on Compared to Younger PatientsIn: Cancers Vol. 16 (2024) Nr. 6, 1231Online Full Text: dx.doi.org/ (Open Access)
-
A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in GlioblastomaIn: Clinical Cancer Research Vol. 29 (2023) Nr. 2, pp. 488 - 500Online Full Text: dx.doi.org/ (Open Access)
-
A novel serum extracellular vesicle protein signature to monitor glioblastoma tumor progressionIn: International Journal of Cancer Vol. 152 (2023) Nr. 2, pp. 308 - 319Online Full Text: dx.doi.org/ (Open Access)
-
Are we providing best available care to newly diagnosed glioblastoma patients? : Systematic review of phase III trials in newly diagnosed glioblastoma 2005-2022In: Neuro-Oncology Advances Vol. 5 (2023) Nr. 1, vdad105Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Feasibility and tolerability of trofosfamide and etoposide in progressive glioblastomaIn: Neuro-Oncology Advances Vol. 5 (2023) Nr. 1, vdad090Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) : a promising target for the immunotherapy of cancerIn: Frontiers in Immunology Vol. 14 (2023) 1173634Online Full Text: dx.doi.org/ (Open Access)
-
Individual glioblastoma cells harbor both proliferative and invasive capabilities during tumor progressionIn: Neuro-Oncology Vol. 25 (2023) Nr. 12, pp. 2150 - 2162Online Full Text: dx.doi.org/
-
Location of Recurrences after Trimodality Treatment for Glioblastoma with Respect to the Delivered Radiation Dose Distribution and Its Influence on PrognosisIn: Cancers Vol. 15 (2023) Nr. 11, 2982Online Full Text: dx.doi.org/ (Open Access)
-
Precision neuro-oncology : A pilot analysis of personalized treatment in recurrent gliomaIn: Journal of Cancer Research and Clinical Oncology Vol. 149 (2023) Nr. 7, pp. 3513 - 3526Online Full Text: dx.doi.org/ (Open Access)
-
Surface Chemistry and Specific Surface Area Rule the Efficiency of Gold Nanoparticle Sensitizers in Proton TherapyIn: Chemistry - A European Journal Vol. 29 (2023) Nr. 50, e202301260Online Full Text: dx.doi.org/ (Open Access)
-
TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entitiesIn: PLoS ONE Vol. 18 (2023) Nr. 7, e0281487Online Full Text: dx.doi.org/ (Open Access)
-
Telemedicine in Neuro-Oncology : An Evaluation of Remote Consultations during the COVID-19 PandemicIn: Cancers Vol. 15 (2023) Nr. 16, 4054Online Full Text: dx.doi.org/ (Open Access)
-
First multicentric real-life experience with the combination of CCNU and temozolomide in newly diagnosed MGMT promoter methylated IDH wildtype glioblastomaIn: Neuro-Oncology Advances Vol. 4 (2022) Nr. 1, pp. vdac137Online Full Text: dx.doi.org/ (Open Access)
-
Machine Learning Applications for Differentiation of Glioma from Brain Metastasis : A Systematic ReviewIn: Cancers Vol. 14 (2022) Nr. 6, 1369Online Full Text: dx.doi.org/ (Open Access)
-
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expressionIn: Nature Communications Vol. 13 (2022) Nr. 1, 156Online Full Text: dx.doi.org/ (Open Access)
-
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumorsIn: Nature Communications Vol. 13 (2022) Nr. 1, 4061Online Full Text: dx.doi.org/ (Open Access)
-
Case Report : Pseudomeningeosis and Demyelinating Metastasis-Like Lesions From Checkpoint Inhibitor Therapy in Malignant MelanomaIn: Frontiers in Oncology Vol. 11 (2021) pp. 637185Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Dosimetric impact of the positioning variation of tumor treating field electrodes in the PriCoTTF-phase I/II trialIn: Journal of Applied Clinical Medical Physics Vol. 22 (2021) Nr. 1, pp. 242 - 250Online Full Text: dx.doi.org/ (Open Access)
-
How about levetiracetam in glioblastoma? An institutional experience and meta‐analysisIn: Cancers Vol. 13 (2021) Nr. 15, 3770Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Leptomeningeal disease from melanoma : Poor prognosis despite new therapeutic modalitiesIn: European Journal of Cancer (EJC) Vol. 148 (2021) pp. 395 - 404Online Full Text: dx.doi.org/
-
Machine learning-based differentiation between multiple sclerosis and glioma WHO II°-IV° using O-(2-[18F] fluoroethyl)-L-tyrosine positron emission tomographyIn: Journal of Neuro-Oncology Vol. 152 (2021) pp. 325 - 332Online Full Text: dx.doi.org/
-
Preoperative and early postoperative seizures in patients with glioblastoma : two sides of the same coin?In: Neuro-Oncology Advances Vol. 3 (2021) Nr. 1, vdaa158Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progressionIn: Nature Communications Vol. 12 (2021) Nr. 1, 3895Online Full Text: dx.doi.org/ (Open Access)
-
Analysis of serum mirna in glioblastoma patients : Cd44-based enrichment of extracellular vesicles enhances specificity for the prognostic signatureIn: International Journal of Molecular Sciences (IJMS) Vol. 21 (2020) Nr. 19, pp. 7211Online Full Text: dx.doi.org/ (Open Access)
-
Challenging Implications of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids Syndrome with an Atypical Presentation : Report of Two CasesIn: World Neurosurgery Vol. 143 (2020) pp. 507 - 512.e1Online Full Text: dx.doi.org/
-
Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinomaIn: International Journal of Cancer Vol. 147 (2020) Nr. 10, pp. 2847 - 2861Online Full Text: dx.doi.org/ (Open Access)
-
Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma : Dosimetric consequences on non-coplanar IMRT as initial results from a phase i trialIn: Radiation Oncology Vol. 15 (2020) Nr. 1, pp. 83Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastomaIn: European Journal of Cancer (EJC) Vol. 140 (2020) pp. 130 - 139Online Full Text: dx.doi.org/
-
Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cellsIn: Journal of Comparative Neurology Vol. 528 (2020) Nr. 7, pp. 1203 - 1215Online Full Text: dx.doi.org/
-
Olfactory function as an independent prognostic factor in glioblastomaIn: Neurology Vol. 94 (2020) Nr. 5, pp. e529 - e537Online Full Text: dx.doi.org/
-
Plasma next generation sequencing and droplet digital-qpcr-based quantification of circulating cell-free rna for noninvasive early detection of cancerIn: Cancers Vol. 12 (2020) Nr. 2, pp. 353Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastomaIn: Journal of Cancer Research and Clinical Oncology Vol. 146 (2020) Nr. 3, pp. 787 - 792Online Full Text: dx.doi.org/
-
3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumorsIn: Nature Communications Vol. 10 (2019) pp. 4529Online Full Text: dx.doi.org/ (Open Access)
-
Comparison of L-Methyl-11C-Methionine PET With Magnetic Resonance Spectroscopy in Detecting Newly Diagnosed GliomaIn: Clinical Nuclear Medicine Vol. 44 (2019) Nr. 6, pp. e375 - e381Online Full Text: dx.doi.org/
-
Hybrid 11C-MET PET/MRI Combined With "Machine Learning" in Glioma Diagnosis According to the Revised Glioma WHO Classification 2016In: Clinical Nuclear Medicine Vol. 44 (2019) Nr. 3, pp. 214 - 220Online Full Text: dx.doi.org/
-
Longitudinal heterogeneity in glioblastoma : moving targets in recurrent versus primary tumorsIn: Journal of Translational Medicine Vol. 17 (2019) Nr. 1, pp. 96Online Full Text: dx.doi.org/ (Open Access)
-
Regorafenib in patients with recurrent high-grade astrocytomaIn: Journal of Cancer Research and Clinical Oncology Vol. 145 (2019) Nr. 4, pp. 1037 - 1042Online Full Text: dx.doi.org/
-
Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV⁶⁰⁰E inhibition in melanomaIn: European Journal of Cancer (EJC) Vol. 109 (2019) pp. 137 - 153Online Full Text: dx.doi.org/
-
Simultaneous primary cancer occurrence of melanoma and pulmonary adenocarcinoma in leptomeningeal metastases: a case reportIn: BMC Cancer Vol. 19 (2019) Nr. 1, pp. 995Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Recurrent pseudoprogression in isocitrate dehydrogenase 1 mutant glioblastomaIn: Journal of Clinical Neuroscience Vol. 53 (2018) pp. 255 - 258Online Full Text: dx.doi.org/
-
Functional Subclone profiling for prediction of treatment-induced intratumor population shifts and discovery of rational drug combinations in human glioblastomaIn: Clinical Cancer Research Vol. 23 (2017) Nr. 2, pp. 562 - 574Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Unsupervised consensus cluster analysis of [18F]-fluoroethyl- L-tyrosine positron emission tomography identified textural features for the diagnosis of pseudoprogression in high-grade gliomaIn: OncoTarget Vol. 8 (2017) Nr. 5, pp. 8294 - 8304Online Full Text: dx.doi.org/ (Open Access)
-
Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine PET imaging for the detection of checkpoint inhibitor-related pseudoprogression in melanoma brain metastasesIn: Neuro-Oncology Vol. 18 (2016) Nr. 10, pp. 1462 - 1464Online Full Text: dx.doi.org/
-
Late Pseudoprogression in Glioblastoma : Diagnostic Value of Dynamic O-(2-[¹⁸ F]fluoroethyl)-L-Tyrosine PETIn: Clinical Cancer Research Vol. 22 (2016) Nr. 9, pp. 2190 - 2196Online Full Text: dx.doi.org/
-
Phase I trial of dovitinib (TKI258) in recurrent glioblastomaIn: Journal of Cancer Research and Clinical Oncology Vol. 142 (2016) Nr. 7, pp. 1581 - 1589Online Full Text: dx.doi.org/
-
Carmustine (BCNU) plus Teniposide (VM26) in recurrent malignant gliomaIn: Oncology Vol. 86 (2014) Nr. 5-6, pp. 369 - 372Online Full Text: dx.doi.org/
-
Anticancer effects of niclosamide in human glioblastomaIn: Clinical Cancer Research Vol. 19 (2013) Nr. 15, pp. 4124 - 4136Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
FLAIR-Only progression in bevacizumab-treated relapsing glioblastoma does not predict short survivalIn: Oncology Vol. 85 (2013) Nr. 3, pp. 191 - 195Online Full Text: dx.doi.org/
-
Vemurafenib for leptomeningeal melanomatosisIn: Journal of Clinical Oncology (JCO) Vol. 31 (2013) Nr. 11,Online Full Text: dx.doi.org/
-
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotypeIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 108 (2011) Nr. 24, pp. 9951 - 9956Online Full Text: dx.doi.org/ (Open Access)
-
Residual tumor cells are unique cellular targets in glioblastomaIn: Annals of Neurology Vol. 68 (2010) Nr. 2, pp. 264 - 269Online Full Text: dx.doi.org/ (Open Access)
-
Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cellsIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 103 (2006) Nr. 29, pp. 11063 - 11068Online Full Text: dx.doi.org/ (Open Access)
-
Phenotypic and functional characterization of adult brain neuropoiesisIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 102 (2005) Nr. 26, pp. 9353 - 9358Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
Functional integration of embryonic stem cell-derived neurons in hippocampal slice culturesIn: Journal of Neuroscience Vol. 23 (2003) Nr. 18, pp. 7075 - 7083Online Full Text: dx.doi.org/ (Open Access)
-
Marrow-mindedness : a perspective on neuropoiesisIn: Trends in Neurosciences: TINS Vol. 22 (1999) Nr. 8, pp. 348 - 357Online Full Text: dx.doi.org/
-
68Ga-NeoB PET for Glioma and Breast Cancer : First Results from a Prospective Observational Trial
Annual Congress of the European Association of Nuclear Medicine, 9-13 September 2023 Vienna, Austria,In: European Journal of Nuclear Medicine and Molecular Imaging Vol. 50 (2023) Nr. 1 supplement, pp. S265Online Full Text: dx.doi.org/ (Open Access) -
Decoding glioblastoma survival : unraveling the prognostic potential of olfactory function in a prospective observational study
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology Vol. 25 (2023) Nr. Suppl. 5, pp. v92 - v92Online Full Text: dx.doi.org/ -
Fet pet sensitivity in primary brain tumors according to cns who 2021 : value and pitfalls in presurgical implementationIn: Neuro-Oncology Vol. 25 (2023) Nr. Suppl. 5, pp. v204 - v205Online Full Text: dx.doi.org/
-
Immunogenicity of an additional dose of covid-19 vaccine in fully vaccinated patients with glioma to evaluate new national vaccination guidelines : a prospective cohort studyIn: Neuro-Oncology Vol. 25 (2023) Nr. Suppl. 5, pp. v63 - v64Online Full Text: dx.doi.org/
-
Investigating safety and efficacy of ttfields prior and concomitant to radiotherapy in newly diagnosed glioblastoma : First results of the pricottf phase I/II trial
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology Vol. 25 (2023) Nr. Suppl. 5, pp. v91 - v92Online Full Text: dx.doi.org/ -
Predicting and targeting clonally expanding, tmz-resistant tumor cells in glioblastoma
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology Vol. 25 (2023) Nr. Suppl. 5, pp. v110 - v110Online Full Text: dx.doi.org/ -
Safety and efcacy of TTFields therapy prior and concomitant to radiotherapy in newly diagnosed glioblastoma : the PriCoTTF phase I/II trialIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Vol. 199 (2023) Nr. Suppl. 1, pp. S32Online Full Text: dx.doi.org/ (Open Access)
-
Temporal muscle thickness as a prognostic marker in a real-life cohort of newly diagnosed MGMT promoter methylated glioblastoma patients : a multicentric imaging analysisIn: Neuro-Oncology Vol. 25 (2023) Nr. Suppl. 5, pp. v192 - v193Online Full Text: dx.doi.org/
-
A Investigating safety and efficacy of TTFields prior and concomitant to radiotherapy in newly diagnosed glioblastoma : The PriCoTTF phase I/II trialIn: Neuro-Oncology Vol. 24 (2022) Nr. Suppl. 2, pp. ii14 - ii14Online Full Text: dx.doi.org/ (Open Access)
-
Combination of Trofosfamide and Etoposide in Recurrent GliomaIn: Neuro-Oncology Vol. 24 (2022) Nr. Suppl. 2, pp. ii89 - ii89Online Full Text: dx.doi.org/ (Open Access)
-
BIOM-24. PROTEIN SURFACE SIGNATURE ON SERUM EXTRACELLULAR VESICLES FOR NON-INVASIVE DETECTION OF TUMOR PROGRESSION IN GLIOBLASTOMA PATIENTS
2021 Society for Neuro-Oncology’s 26th Annual Scientific Meeting and Education Day,In: Neuro-Oncology Vol. 23 (2021) Nr. Supplement_6, pp. vi15 - vi16Online Full Text: dx.doi.org/ (Open Access) -
PRICOTTF trial : A phase I/II trial of TTfields prior and concomitant to radiotherapy in newly diagnosed glioblastomaIn: Neuro-Oncology Vol. 23 (2021) Nr. Suppl. 2, pp. 50
-
PriCoTTF Trial : A Phase I//II Trial of TTFields Prior and Concomitant to Radiotherapy in newly diagnosed Glioblastoma
2021 Society for Neuro-Oncology’s 26th Annual Scientific Meeting and Education Day,In: Neuro-Oncology Vol. 23 (2021) Nr. Supplement_6, pp. vi68 - vi68Online Full Text: dx.doi.org/ (Open Access) -
Analysis of serum mirna in glioblastoma patients : Targeted erichment of extracellular vesicles enhances specificity for prognostic signatureIn: Neuro-Oncology Vol. 22 (2020) Nr. Supplement 2, pp. 10Online Full Text: dx.doi.org/ (Open Access)
-
Deep learning enabled prediction of isocitrate dehydrogenase mutation status from digtial histapathology data in glioblastomaIn: Neuro-Oncology Vol. 22 (2020) Nr. Supplement 2, pp. ii167Online Full Text: dx.doi.org/ (Open Access)
-
Evaluation der dosimetrischen Auswirkungen der geometrischen Variation der Tumor Treating Field (TTF) Elektroden-Positionierung in der PriCoTTF-Phase I/II Studie
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. Juni - 28. Juni 2020, Wiesbaden, Germany,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Vol. 196 (2020) Nr. 1 Supplement: Abstracts DEGRO 2020, pp. S65Online Full Text: dx.doi.org/ (Open Access) -
PriCoTTF Trial : A phase I/II trial of TTFields prior and concomitant to radiotherapy in newly diagnosed glioblastoma
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. - 28. Juni 2020, Wiesbaden, Germany,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Vol. 196 (2020) Nr. 1 Supplement: Abstracts DEGRO 2020, pp. S74Online Full Text: dx.doi.org/ (Open Access) -
Pricottf trial : a phase I/II trial of ttfields prior and concomitant to radiotherapy in newly diagnosed glioblastomaIn: Neuro-Oncology Vol. 22 (2020) Nr. Supplement_2, pp. ii61 - ii61Online Full Text: dx.doi.org/ Online Full Text (Open Access)
-
ACTR-49. PriCoTTF: A PHASE I/II TRIAL OF TUMOR TREATING FIELDS PRIOR AND CONCOMITANT TO RADIOTHERAPY IN NEWLY DIAGNOSED GLIOBLASTOMA
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology Vol. 20 (2018) Nr. suppl_6, pp. vi22 - vi23Online Full Text: dx.doi.org/ (Open Access) -
CBMT-17. NOVEL APPROACH OF UTILISING SERUM/PLASMA EV AND CELL-FREE RNA FOR TREATMENT MONITORING IN GLIOBLASTOMA PATIENTSIn: Neuro-Oncology Vol. 20 (2018) Nr. suppl_6, pp. vi35 - vi36Online Full Text: dx.doi.org/ (Open Access)
-
HOUT-30. TUMOR TREATING FIELDS (TTFIELDS) IN COMBINATION WITH LOMUSTINE (CCNU) AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM)
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology Vol. 20 (2018) Nr. suppl_6, pp. vi119 - vi120Online Full Text: dx.doi.org/ (Open Access) -
NIMG-32. COMPARISON OF L-METHYL-11C-METHIONINE POSITRON EMISSION TOMOGRAPHY WITH MAGNETIC RESONANCE SPECTROSCOPY IN DETECTING NEWLY DIAGNOSED GLIOMA
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology Vol. 20 (2018) Nr. suppl_6, pp. vi182 - vi183Online Full Text: dx.doi.org/ (Open Access)