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DKFZ-Abteilung für Translationale Neuroonkologie am WTZ - Universitätsklinikum Essen
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Funktionen
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Professorinnen/Professoren, Experimentelle Immunologie und Bildgebung
Aktuelle Veranstaltungen
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SoSe 2025
Vergangene Veranstaltungen (max. 10)
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SoSe 2024
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SoSe 2023
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SoSe 2022
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SoSe 2021
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Cranioencephalic functional lymphoid units in glioblastomaIn: Nature Medicine , Jg. 30 2024 , Nr. 10 , S. 2947 - 2956DOI (Open Access)
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KDM5B predicts temozolomide-resistant subclones in glioblastomaIn: iScience , Jg. 27 2024 , Nr. 1 , 108596DOI (Open Access)
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Predictors and surgical outcome of hemorrhagic metastatic brain malignanciesIn: Journal of Neuro-Oncology , Jg. 169 2024 , Nr. 1 , S. 165 - 173DOI (Open Access)
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The Role of Fibroblast Activation Protein in Glioblastoma and Gliosarcoma : A Comparison of Tissue, ⁶⁸Ga-FAPI-46 PET Data, and Survival DataIn: Journal of Nuclear Medicine (JNM) , Jg. 65 2024 , Nr. 8 , S. 1217 - 1223
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The influence of radiological tumor growth pattern on sino‑nasal health in pituitary adenomasIn: Oncology Letters , Jg. 27 2024 , Nr. 3 , 125DOI (Open Access)
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Treatment Strategies for Glioblastoma in the Elderly : What Should We Focus on Compared to Younger PatientsIn: Cancers , Jg. 16 2024 , Nr. 6 , 1231DOI, Online Volltext (Open Access)
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A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in GlioblastomaIn: Clinical Cancer Research , Jg. 29 2023 , Nr. 2 , S. 488 - 500DOI (Open Access)
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A novel serum extracellular vesicle protein signature to monitor glioblastoma tumor progressionIn: International Journal of Cancer , Jg. 152 2023 , Nr. 2 , S. 308 - 319DOI (Open Access)
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Are we providing best available care to newly diagnosed glioblastoma patients? : Systematic review of phase III trials in newly diagnosed glioblastoma 2005-2022In: Neuro-Oncology Advances , Jg. 5 2023 , Nr. 1 , vdad105DOI, Online Volltext (Open Access)
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Feasibility and tolerability of trofosfamide and etoposide in progressive glioblastomaIn: Neuro-Oncology Advances , Jg. 5 2023 , Nr. 1 , vdad090DOI, Online Volltext (Open Access)
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Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) : a promising target for the immunotherapy of cancerIn: Frontiers in Immunology , Jg. 14 2023 , 1173634DOI (Open Access)
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Individual glioblastoma cells harbor both proliferative and invasive capabilities during tumor progressionIn: Neuro-Oncology , Jg. 25 2023 , Nr. 12 , S. 2150 - 2162DOI (Open Access)
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Location of Recurrences after Trimodality Treatment for Glioblastoma with Respect to the Delivered Radiation Dose Distribution and Its Influence on PrognosisIn: Cancers , Jg. 15 2023 , Nr. 11 , 2982DOI (Open Access)
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Precision neuro-oncology : A pilot analysis of personalized treatment in recurrent gliomaIn: Journal of Cancer Research and Clinical Oncology , Jg. 149 2023 , Nr. 7 , S. 3513 - 3526DOI (Open Access)
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Surface Chemistry and Specific Surface Area Rule the Efficiency of Gold Nanoparticle Sensitizers in Proton TherapyIn: Chemistry - A European Journal , Jg. 29 2023 , Nr. 50 , e202301260DOI (Open Access)
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TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entitiesIn: PLoS ONE , Jg. 18 2023 , Nr. 7 , e0281487DOI (Open Access)
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Telemedicine in Neuro-Oncology : An Evaluation of Remote Consultations during the COVID-19 PandemicIn: Cancers , Jg. 15 2023 , Nr. 16 , 4054DOI (Open Access)
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First multicentric real-life experience with the combination of CCNU and temozolomide in newly diagnosed MGMT promoter methylated IDH wildtype glioblastomaIn: Neuro-Oncology Advances , Jg. 4 2022 , Nr. 1 , S. vdac137DOI (Open Access)
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Machine Learning Applications for Differentiation of Glioma from Brain Metastasis : A Systematic ReviewIn: Cancers , Jg. 14 2022 , Nr. 6 , 1369DOI (Open Access)
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Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expressionIn: Nature Communications , Jg. 13 2022 , Nr. 1 , 156DOI (Open Access)
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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumorsIn: Nature Communications , Jg. 13 2022 , Nr. 1 , 4061DOI (Open Access)
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Case Report : Pseudomeningeosis and Demyelinating Metastasis-Like Lesions From Checkpoint Inhibitor Therapy in Malignant MelanomaIn: Frontiers in Oncology , Jg. 11 2021 , S. 637185DOI, Online Volltext (Open Access)
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Dosimetric impact of the positioning variation of tumor treating field electrodes in the PriCoTTF-phase I/II trialIn: Journal of Applied Clinical Medical Physics , Jg. 22 2021 , Nr. 1 , S. 242 - 250DOI, Online Volltext (Open Access)
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How about levetiracetam in glioblastoma? An institutional experience and meta‐analysisIn: Cancers , Jg. 13 2021 , Nr. 15 , 3770DOI, Online Volltext (Open Access)
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Leptomeningeal disease from melanoma : Poor prognosis despite new therapeutic modalitiesIn: European Journal of Cancer (EJC) , Jg. 148 2021 , S. 395 - 404
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Machine learning-based differentiation between multiple sclerosis and glioma WHO II°-IV° using O-(2-[18F] fluoroethyl)-L-tyrosine positron emission tomographyIn: Journal of Neuro-Oncology , Jg. 152 2021 , S. 325 - 332
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Preoperative and early postoperative seizures in patients with glioblastoma : two sides of the same coin?In: Neuro-Oncology Advances , Jg. 3 2021 , Nr. 1 , vdaa158DOI, Online Volltext (Open Access)
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Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progressionIn: Nature Communications , Jg. 12 2021 , Nr. 1 , 3895DOI (Open Access)
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Analysis of serum mirna in glioblastoma patients : Cd44-based enrichment of extracellular vesicles enhances specificity for the prognostic signatureIn: International Journal of Molecular Sciences (IJMS) , Jg. 21 2020 , Nr. 19 , S. 7211DOI (Open Access)
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Challenging Implications of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids Syndrome with an Atypical Presentation : Report of Two CasesIn: World Neurosurgery , Jg. 143 2020 , S. 507 - 512.e1
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Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinomaIn: International Journal of Cancer , Jg. 147 2020 , Nr. 10 , S. 2847 - 2861DOI (Open Access)
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Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma : Dosimetric consequences on non-coplanar IMRT as initial results from a phase i trialIn: Radiation Oncology , Jg. 15 2020 , Nr. 1 , S. 83DOI, Online Volltext (Open Access)
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Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastomaIn: European Journal of Cancer (EJC) , Jg. 140 2020 , S. 130 - 139
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Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cellsIn: Journal of Comparative Neurology , Jg. 528 2020 , Nr. 7 , S. 1203 - 1215
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Olfactory function as an independent prognostic factor in glioblastomaIn: Neurology , Jg. 94 2020 , Nr. 5 , S. e529 - e537
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Plasma next generation sequencing and droplet digital-qpcr-based quantification of circulating cell-free rna for noninvasive early detection of cancerIn: Cancers , Jg. 12 2020 , Nr. 2 , S. 353DOI, Online Volltext (Open Access)
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Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastomaIn: Journal of Cancer Research and Clinical Oncology , Jg. 146 2020 , Nr. 3 , S. 787 - 792
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3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumorsIn: Nature Communications , Jg. 10 2019 , S. 4529DOI (Open Access)
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Comparison of L-Methyl-11C-Methionine PET With Magnetic Resonance Spectroscopy in Detecting Newly Diagnosed GliomaIn: Clinical Nuclear Medicine , Jg. 44 2019 , Nr. 6 , S. e375 - e381
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Hybrid 11C-MET PET/MRI Combined With "Machine Learning" in Glioma Diagnosis According to the Revised Glioma WHO Classification 2016In: Clinical Nuclear Medicine , Jg. 44 2019 , Nr. 3 , S. 214 - 220
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Longitudinal heterogeneity in glioblastoma : moving targets in recurrent versus primary tumorsIn: Journal of Translational Medicine , Jg. 17 2019 , Nr. 1 , S. 96DOI (Open Access)
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Regorafenib in patients with recurrent high-grade astrocytomaIn: Journal of Cancer Research and Clinical Oncology , Jg. 145 2019 , Nr. 4 , S. 1037 - 1042
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Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV⁶⁰⁰E inhibition in melanomaIn: European Journal of Cancer (EJC) , Jg. 109 2019 , S. 137 - 153
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Simultaneous primary cancer occurrence of melanoma and pulmonary adenocarcinoma in leptomeningeal metastases: a case reportIn: BMC Cancer , Jg. 19 2019 , Nr. 1 , S. 995DOI, Online Volltext (Open Access)
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Recurrent pseudoprogression in isocitrate dehydrogenase 1 mutant glioblastomaIn: Journal of Clinical Neuroscience , Jg. 53 2018 , S. 255 - 258
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Functional Subclone profiling for prediction of treatment-induced intratumor population shifts and discovery of rational drug combinations in human glioblastomaIn: Clinical Cancer Research , Jg. 23 2017 , Nr. 2 , S. 562 - 574DOI (Open Access)
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Unsupervised consensus cluster analysis of [18F]-fluoroethyl- L-tyrosine positron emission tomography identified textural features for the diagnosis of pseudoprogression in high-grade gliomaIn: OncoTarget , Jg. 8 2017 , Nr. 5 , S. 8294 - 8304DOI (Open Access)
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Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine PET imaging for the detection of checkpoint inhibitor-related pseudoprogression in melanoma brain metastasesIn: Neuro-Oncology , Jg. 18 2016 , Nr. 10 , S. 1462 - 1464
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Late Pseudoprogression in Glioblastoma : Diagnostic Value of Dynamic O-(2-[¹⁸ F]fluoroethyl)-L-Tyrosine PETIn: Clinical Cancer Research , Jg. 22 2016 , Nr. 9 , S. 2190 - 2196
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Phase I trial of dovitinib (TKI258) in recurrent glioblastomaIn: Journal of Cancer Research and Clinical Oncology , Jg. 142 2016 , Nr. 7 , S. 1581 - 1589
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Carmustine (BCNU) plus Teniposide (VM26) in recurrent malignant gliomaIn: Oncology , Jg. 86 2014 , Nr. 5-6 , S. 369 - 372
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Anticancer effects of niclosamide in human glioblastomaIn: Clinical Cancer Research , Jg. 19 2013 , Nr. 15 , S. 4124 - 4136DOI (Open Access)
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FLAIR-Only progression in bevacizumab-treated relapsing glioblastoma does not predict short survivalIn: Oncology , Jg. 85 2013 , Nr. 3 , S. 191 - 195
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Vemurafenib for leptomeningeal melanomatosisIn: Journal of Clinical Oncology (JCO) , Jg. 31 2013 , Nr. 11
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c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotypeIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 108 2011 , Nr. 24 , S. 9951 - 9956DOI (Open Access)
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Residual tumor cells are unique cellular targets in glioblastomaIn: Annals of Neurology , Jg. 68 2010 , Nr. 2 , S. 264 - 269DOI (Open Access)
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Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cellsIn: Proceedings of the National Academy of Sciences of the United States of America , Jg. 103 2006 , Nr. 29 , S. 11063 - 11068DOI (Open Access)
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Phenotypic and functional characterization of adult brain neuropoiesisIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 102 2005 , Nr. 26 , S. 9353 - 9358DOI (Open Access)
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Functional integration of embryonic stem cell-derived neurons in hippocampal slice culturesIn: Journal of Neuroscience , Jg. 23 2003 , Nr. 18 , S. 7075 - 7083DOI (Open Access)
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Marrow-mindedness : a perspective on neuropoiesisIn: Trends in Neurosciences: TINS , Jg. 22 1999 , Nr. 8 , S. 348 - 357
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AI Based Prediction of Clinical TTFields Response in Glioblastoma Patients (Retrospective Analysis)
29th Annual Meeting and Education Day of the Society-for-Neuro-Oncology (SNO): NOV 21-24, 2024; Houston, USA,In: Neuro-Oncology , Jg. 26 2024 , Nr. Suppl. 8: Abstracts from the 2024 Society for Neuro-Oncology’s 29th Annual Meeting and Education Day , S. viii112 - viii112 -
Decoding glioblastoma survival : Unraveling the prognostic potential of olfactory function in a prospective observational study
29th Annual Meeting and Education Day of the Society-for-Neuro-Oncology (SNO): NOV 21-24, 2024; Houston, USA,In: Neuro-Oncology , Jg. 26 2024 , Nr. Suppl. 8: Abstracts from the 2024 Society for Neuro-Oncology’s 29th Annual Meeting and Education Day , S. viii95 - viii95 -
68Ga-NeoB PET for Glioma and Breast Cancer : First Results from a Prospective Observational Trial
Annual Congress of the European Association of Nuclear Medicine, 9-13 September 2023 Vienna, Austria,In: European Journal of Nuclear Medicine and Molecular Imaging , Jg. 50 2023 , Nr. 1 supplement , S. S265 -
Decoding glioblastoma survival : unraveling the prognostic potential of olfactory function in a prospective observational study
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology , Jg. 25 2023 , Nr. Suppl. 5 , S. v92 - v92 -
Fet pet sensitivity in primary brain tumors according to cns who 2021 : value and pitfalls in presurgical implementationIn: Neuro-Oncology , Jg. 25 2023 , Nr. Suppl. 5 , S. v204 - v205
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Immunogenicity of an additional dose of covid-19 vaccine in fully vaccinated patients with glioma to evaluate new national vaccination guidelines : a prospective cohort studyIn: Neuro-Oncology , Jg. 25 2023 , Nr. Suppl. 5 , S. v63 - v64
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Investigating safety and efficacy of ttfields prior and concomitant to radiotherapy in newly diagnosed glioblastoma : First results of the pricottf phase I/II trial
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology , Jg. 25 2023 , Nr. Suppl. 5 , S. v91 - v92 -
Predicting and targeting clonally expanding, tmz-resistant tumor cells in glioblastoma
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology , Jg. 25 2023 , Nr. Suppl. 5 , S. v110 - v110 -
Safety and efcacy of TTFields therapy prior and concomitant to radiotherapy in newly diagnosed glioblastoma : the PriCoTTF phase I/II trialIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 199 2023 , Nr. Suppl. 1 , S. S32DOI (Open Access)
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Temporal muscle thickness as a prognostic marker in a real-life cohort of newly diagnosed MGMT promoter methylated glioblastoma patients : a multicentric imaging analysisIn: Neuro-Oncology , Jg. 25 2023 , Nr. Suppl. 5 , S. v192 - v193
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A Investigating safety and efficacy of TTFields prior and concomitant to radiotherapy in newly diagnosed glioblastoma : The PriCoTTF phase I/II trialIn: Neuro-Oncology , Jg. 24 2022 , Nr. Suppl. 2 , S. ii14 - ii14DOI (Open Access)
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Combination of Trofosfamide and Etoposide in Recurrent GliomaIn: Neuro-Oncology , Jg. 24 2022 , Nr. Suppl. 2 , S. ii89 - ii89DOI (Open Access)
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BIOM-24. PROTEIN SURFACE SIGNATURE ON SERUM EXTRACELLULAR VESICLES FOR NON-INVASIVE DETECTION OF TUMOR PROGRESSION IN GLIOBLASTOMA PATIENTS
2021 Society for Neuro-Oncology’s 26th Annual Scientific Meeting and Education Day,In: Neuro-Oncology , Jg. 23 2021 , Nr. Supplement_6 , S. vi15 - vi16DOI (Open Access) -
PRICOTTF trial : A phase I/II trial of TTfields prior and concomitant to radiotherapy in newly diagnosed glioblastomaIn: Neuro-Oncology , Jg. 23 2021 , Nr. Suppl. 2 , S. 50
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PriCoTTF Trial : A Phase I//II Trial of TTFields Prior and Concomitant to Radiotherapy in newly diagnosed Glioblastoma
2021 Society for Neuro-Oncology’s 26th Annual Scientific Meeting and Education Day,In: Neuro-Oncology , Jg. 23 2021 , Nr. Supplement_6 , S. vi68 - vi68DOI (Open Access) -
Analysis of serum mirna in glioblastoma patients : Targeted erichment of extracellular vesicles enhances specificity for prognostic signatureIn: Neuro-Oncology , Jg. 22 2020 , Nr. Supplement 2 , S. 10DOI (Open Access)
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Deep learning enabled prediction of isocitrate dehydrogenase mutation status from digtial histapathology data in glioblastomaIn: Neuro-Oncology , Jg. 22 2020 , Nr. Supplement 2 , S. ii167DOI (Open Access)
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Evaluation der dosimetrischen Auswirkungen der geometrischen Variation der Tumor Treating Field (TTF) Elektroden-Positionierung in der PriCoTTF-Phase I/II Studie
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. Juni - 28. Juni 2020, Wiesbaden, Germany,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 196 2020 , Nr. 1 Supplement: Abstracts DEGRO 2020 , S. S65DOI (Open Access) -
PriCoTTF Trial : A phase I/II trial of TTFields prior and concomitant to radiotherapy in newly diagnosed glioblastoma
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. - 28. Juni 2020, Wiesbaden, Germany,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 196 2020 , Nr. 1 Supplement: Abstracts DEGRO 2020 , S. S74DOI (Open Access) -
Pricottf trial : a phase I/II trial of ttfields prior and concomitant to radiotherapy in newly diagnosed glioblastomaIn: Neuro-Oncology , Jg. 22 2020 , Nr. Supplement_2 , S. ii61 - ii61DOI (Open Access)
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ACTR-49. PriCoTTF: A PHASE I/II TRIAL OF TUMOR TREATING FIELDS PRIOR AND CONCOMITANT TO RADIOTHERAPY IN NEWLY DIAGNOSED GLIOBLASTOMA
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology , Jg. 20 2018 , Nr. suppl_6 , S. vi22 - vi23DOI (Open Access) -
CBMT-17. NOVEL APPROACH OF UTILISING SERUM/PLASMA EV AND CELL-FREE RNA FOR TREATMENT MONITORING IN GLIOBLASTOMA PATIENTSIn: Neuro-Oncology , Jg. 20 2018 , Nr. suppl_6 , S. vi35 - vi36DOI (Open Access)
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HOUT-30. TUMOR TREATING FIELDS (TTFIELDS) IN COMBINATION WITH LOMUSTINE (CCNU) AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM)
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology , Jg. 20 2018 , Nr. suppl_6 , S. vi119 - vi120DOI (Open Access) -
NIMG-32. COMPARISON OF L-METHYL-11C-METHIONINE POSITRON EMISSION TOMOGRAPHY WITH MAGNETIC RESONANCE SPECTROSCOPY IN DETECTING NEWLY DIAGNOSED GLIOMA
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology , Jg. 20 2018 , Nr. suppl_6 , S. vi182 - vi183DOI (Open Access) -
Redirecting resistance evolution in BRAFV600 melanoma by inhibition of the peroxiredoxin-thioredoxin system2025DOI (Open Access)