Faculty of Biology

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Address
Hufelandstr. 55
45122 Essen

Functions

  • Geschäftsführende/r Direktor/in, Institut für Physiologie

  • Stellv. Vorsitz, Prüfungsausschuss für Medizinische Biologie

  • ---, Hochschulbeauftragte/r für Prüfungsfragen


    Address
    Hufelandstraße 55
    45122 Essen
  • Professorinnen/Professoren, Fachbereichsrat

  • Prodekan/in (Studium und Lehre), Dekanat Medizin

The following publications are listed in the online university bibliography of the University of Duisburg-Essen. Further information may also be found on the person's personal web pages.

    Journal articles

  • Aboouf, Mostafa A.; Armbruster, Julia; Guscetti, Franco; Thiersch, Markus; Boss, Andreas; Gödecke, Axel; Winning, Sandra; Padberg, Claudia; Fandrey, Joachim; Kristiansen, Glen; Bicker, Anne; Hankeln, Thomas; Gassmann, Max; Gorr, Thomas A.
    Endogenous myoglobin expression in mouse models of mammary carcinoma reduces hypoxia and metastasis in PyMT mice
    In: Scientific Reports Vol. 13 (2023) Nr. 1, 7530
  • Leu, Tristan; Denda, Jannik; Wrobeln, Anna; Fandrey, Joachim
    Hypoxia-Inducible Factor-2alpha Affects the MEK/ERK Signaling Pathway via Primary Cilia in Connection with the Intraflagellar Transport Protein 88 Homolog
    In: Molecular and Cellular Biology (MCB) Vol. 43 (2023) Nr. 4, pp. 174 - 183
  • Schild, Yves; Bosserhoff, Jonah; Droege, Freya; Littwitz-Salomon, Elisabeth; Fandrey, Joachim; Wrobeln, Anna
    Hypoxia-Inducible Factor–Prolyl Hydroxylase Inhibitor Improves Leukocyte Energy Metabolism in Hereditary Hemorrhagic Telangiectasia
    In: Life Vol. 13 (2023) Nr. 8, 1708
  • Kobus, Susann; Felderhoff-Müser, Ursula; Lainka, Elke; Fandrey, Joachim; Benson, Sven
    Music Therapy as a Topic in Medical Education : Course Concept and Student Evaluation of an Elective Course for Medical Students
    In: Journal of Medical Education and Curricular Development Vol. 11 (2023) in press
  • Pelletier, Abigaelle; Nelius, Eric; Fan, Zheng; Khatchatourova, Ekaterina; Alvarado-Diaz, Abdiel; He, Jingyi; Krzywinska, Ewelina; Sobecki, Michal; Nagarajan, Shunmugam; Kerdiles, Yann; Fandrey, Joachim; Gotthardt, Dagmar; Sexl, Veronika; de Bock, Katrien; Stockmann, Christian
    Resting natural killer cell homeostasis relies on tryptophan/NAD⁺ metabolism and HIF-1α
    In: EMBO Reports (2023) e56156
  • Sperber, Hannah S.; Raymond, Kyle A.; Bouzidi, Mohamed S.; Ma, Tongcui; Valdebenito, Silvana; Eugenin, Eliseo A.; Roan, Nadia R.; Deeks, Steven G.; Winning, Sandra; Fandrey, Joachim; Schwarzer, Roland; Pillai, Satish K.
    The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency
    In: Cell Reports Vol. 42 (2023) Nr. 11, 113285
  • Kragesteen, Bjørt K.; Giladi, Amir; David, Eyal; Halevi, Shahar; Geirsdóttir, Laufey; Lempke, Olga M.; Li, Baoguo; Bapst, Andreas M.; Xie, Ken; Katzenelenbogen, Yonatan; Dahl, Sophie L.; Sheban, Fadi; Gurevich-Shapiro, Anna; Zada, Mor; Phan, Truong San; Avellino, Roberto; Wang, Shuang-Yin; Barboy, Oren; Shlomi-Loubaton, Shir; Winning, Sandra; Markwerth, Philipp P.; Dekalo, Snir; Keren-Shaul, Hadas; Kedmi, Merav; Sikora, Martin; Fandrey, Joachim; Korneliussen, Thorfinn S.; Prchal, Josef T.; Rosenzweig, Barak; Yutkin, Vladimir; Racimo, Fernando; Willerslev, Eske; Gur, Chamutal; Wenger, Roland H.; Amit, Ido
    The transcriptional and regulatory identity of erythropoietin producing cells
    In: Nature Medicine Vol. 29 (2023) Nr. 5, pp. 1191 - 1200
  • Wrobeln, Anna; Leu, Tristan; Jablonska, Jadwiga; Geisthoff, Urban; Lang, Stephan; Fandrey, Joachim; Droege, Freya
    Altered hypoxia inducible factor regulation in hereditary haemorrhagic telangiectasia
    In: Scientific Reports Vol. 12 (2022) Nr. 1, 5877
  • Henning, Yoshiyuki; Blind, Ursula Sarah; Larafa, Safa; Matschke, Johann; Fandrey, Joachim
    Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction
    In: Cell Death and Disease Vol. 13 (2022) Nr. 7, 662
  • Schützhold, Vera; Gravemeyer, Jan; Bicker, Anne; Hager, Thomas; Padberg, Claudia; Schäfer, Jana; Wrobeln, Anna; Steinbrink, Melanie; Zeynel, Seher; Hankeln, Thomas; Becker, Jürgen Christian; Fandrey, Joachim; Winning, Sandra
    Knockout of Factor-Inhibiting HIF (Hif1an) in Colon Epithelium Attenuates Chronic Colitis but Does Not Reduce Colorectal Cancer in Mice
    In: The Journal of Immunology (JI) Vol. 208 (2022) Nr. 5, pp. 1280 - 1291
  • Winning, Sandra; Fandrey, Joachim
    Oxygen Sensing in Innate Immune Cells : How Inflammation Broadens Classical Hypoxia-Inducible Factor Regulation in Myeloid Cells
    In: Antioxidants and Redox Signaling Vol. 37 (2022) Nr. 13, pp. 956 - 971
  • Fandrey, Joachim
    The endocrine kidney : tampering with oxygen sensors may change your character
    In: Journal of Physiology Vol. 600 (2022) Nr. 3, pp. 425 - 426
  • Krzywinska, Ewelina; Sobecki, Michal; Nagarajan, Shunmugam; Zacharjasz, Julian; Tambuwala, Murtaza M.; Pelletier, Abigaelle; Cummins, Eoin; Gotthardt, Dagmar; Fandrey, Joachim; Kerdiles, Yann M.; Peyssonnaux, Carole; Taylor, Cormac T.; Sexl, Veronika; Stockmann, Christian
    The transcription factor HIF-1α mediates plasticity of NKp46+ innate lymphoid cells in the gut
    In: Journal of Experimental Medicine (JEM) Vol. 219 (2022) Nr. 2, e20210909
  • Leu, Tristan; Fandrey, Joachim; Schreiber, Timm
    (H)IF applicable: promotion of neurogenesis by induced HIF-2 signalling after ischaemia
    In: Pflügers Archiv: European Journal of Physiology Vol. 473 (2021) Nr. 8, pp. 1287 - 1299
  • Quinting, Theresa; Heymann, Anna Katharina; Bicker, Anne; Nauth, Theresa; Bernardini, Andre; Hankeln, Thomas; Fandrey, Joachim; Schreiber, Timm
    Myoglobin Protects Breast Cancer Cells Due to Its ROS and NO Scavenging Properties
    In: Frontiers in Endocrinology Vol. 12 (2021) 732190
  • Sobecki, Michal; Krzywinska, Ewelina; Nagarajan, Shunmugam; Audigé, Annette; Huỳnh, Khanh; Zacharjasz, Julian; Debbache, Julien; Kerdiles, Yann; Gotthardt, Dagmar; Takeda, Norihiko; Fandrey, Joachim; Sommer, Lukas; Sexl, Veronika; Stockmann, Christian
    NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence
    In: Nature Communications Vol. 12 (2021) Nr. 1, 4700
  • Schönberger, Tina; Fandrey, Joachim; Prost-Fingerle, Katrin
    Ways into Understanding HIF Inhibition
    In: Cancers Vol. 13 (2021) Nr. 1, pp. 159
  • Wrobeln, Anna; Jägers, Johannes; Quinting, Theresa; Schreiber, Timm; Kirsch, Michael; Fandrey, Joachim; Ferenz, Katja
    Albumin-derived perfluorocarbon-based artificial oxygen carriers can avoid hypoxic tissue damage in massive hemodilution
    In: Scientific Reports Vol. 10 (2020) Nr. 1, pp. 11950
  • Bernardini, André; Wolf, Alexandra; Brockmeier, Ulf; Riffkin, Helena; Metzen, Eric; Acker-Palmer, Amparo; Fandrey, Joachim; Acker, Helmut
    Carotid body type I cells engage flavoprotein and Pin1 for oxygen sensing
    In: American Journal of Physiology: Cell Physiology Vol. 318 (2020) Nr. 4, pp. C719 - C731
  • Kleszka, Kira; Leu, Tristan; Quinting, Theresa; Jastrow, Holger; Pechlivanis, Sonali; Fandrey, Joachim; Schreiber, Timm
    Hypoxia-inducible factor-2α is crucial for proper brain development
    In: Scientific Reports Vol. 10 (2020) Nr. 1, 19146
  • Settelmeier, Stephan; Schreiber, Timm; Mäki, Joni; Byts, Nadiya; Koivunen, Peppi; Myllyharju, Johanna; Fandrey, Joachim; Winning, Sandra
    Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice
    In: PLoS ONE Vol. 15 (2020) Nr. 5, pp. e0233261
  • Dewan, Monia Vanessa; Serdar, Meray; van de Looij, Yohan; Kowallick, Mirjam; Hadamitzky, Martin; Endesfelder, Stefanie; Fandrey, Joachim; Sizonenko, Stéphane V.; Herz, Josephine; Felderhoff-Müser, Ursula; Bendix, Ivo
    Repetitive Erythropoietin Treatment Improves Long-Term Neurocognitive Outcome by Attenuating Hyperoxia-Induced Hypomyelination in the Developing Brain
    In: Frontiers in Neurology Vol. 11 (2020) pp. 804
  • Kerber, Evelyn L.; Padberg, Claudia; Koll, Nora; Schuetzhold, Vera; Fandrey, Joachim; Winning, Sandra
    The importance of hypoxia-inducible factors (Hif-1 and hif-2) for the pathophysiology of inflammatory bowel disease
    In: International Journal of Molecular Sciences (IJMS) Vol. 21 (2020) Nr. 22, pp. 8551
  • Bicker, Anne; Nauth, Theresa; Gerst, Daniela; Aboouf, Mostafa Ahmed; Fandrey, Joachim; Kristiansen, Glen; Gorr, Thomas Alexander; Hankeln, Thomas
    The role of myoglobin in epithelial cancers : Insights from transcriptomics
    In: International Journal of Molecular Medicine Vol. 45 (2020) Nr. 2, pp. 385 - 400
  • Stokvis, A.; Cantore, M.; Fandrey, Joachim; Ferenz, Katja;
    Application and effects of artificial oxygen carriers in pO2-controlled kidney cell culture
    98th Meeting of the German Physiological Society, 30 September ‐ 2 October 2019, Ulm, Germany,
    In: Acta Physiologica Vol. 227 (2019) Nr. S719, B 04-3
  • Korencak, Marek; Byrne, Morgan; Richter, Enrico; Schultz, Bruce T.; Juszczak, Patrick; Ake, Julie A.; Ganesan, Anuradha; Okulicz, Jason F.; Robb, Merlin L.; De Los Reyes, Buena; Winning, Sandra; Fandrey, Joachim; Burgess, Timothy H.; Esser, Stefan; Michael, Nelson L.; Agan, Brian K.; Streeck, Hendrik
    Effect of HIV infection and antiretroviral therapy on immune cellular functions
    In: JCI Insight Vol. 4 (2019) Nr. 12, :e126675
  • Fandrey, Joachim; Schödel, Johannes; Eckardt, Kai-Uwe; Katschinski, Dörthe M.; Wenger, Roland H.
    Now a Nobel gas : oxygen
    In: Pflügers Archiv: European Journal of Physiology Vol. 471 (2019) Nr. 11/12, pp. 1343 - 1358
  • Schreiber, Timm; Salhöfer, Luca; Quinting, Theresa; Fandrey, Joachim
    Things get broken : the hypoxia-inducible factor prolyl hydroxylases in ischemic heart disease
    In: Basic Research in Cardiology Vol. 114 (2019) Nr. 3, pp. 16
  • Leu, Tristan; Schützhold, Vera; Fandrey, Joachim; Ferenz, Katja
    When the brain yearns for oxygen
    In: Neurosignals Vol. 27 (2019) Nr. 1, pp. 50 - 61
  • Glaser, Ulrike G; Fandrey, Joachim
    Sphingolipids in inflammatory hypoxia
    In: Biological Chemistry Vol. 399 (2018) Nr. 10, pp. 1169 - 1174
  • Fandrey, Joachim
    Wie wird die Bildung von Erythropoietin gesteuert?
    In: Der Nephrologe Vol. 13 (2018) Nr. 4, pp. 270 - 272
  • Kantari-Mimoun, Chahrazade; Krzywinska, Ewelina; Castells, Magali; Milien, Corinne; Klose, Ralph; Meinecke, Anna-Katharina; Lemberger, Ursula; Mathivet, Thomas; Gojkovic, Milos; Schrödter, Katrin; Österreicher, Christoph; Fandrey, Joachim; Rundqvist, Helene; Stockmann, Christian
    Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice
    In: OncoTarget Vol. 8 (2017) Nr. 9, pp. 15085 - 15100
  • Kleszka, K.; Pechlivanis, Sonali; Fandrey, Joachim; Schreiber, T.
    Defective brain development in mice lacking hypoxia-inducible factor-2a in neural stem cells
    In: Acta Physiologica Vol. 219 S711 (2017) pp. 54 - 54
  • Schuler, Martin; Paz-Ares, L.; Sequist, L. V.; Wu, Y. L.; Geater, S. L.; Marten, A.; Fandrey, Joachim; Park, K.; Yang, JCH
    First-line afatinib for advanced EGFRm1 NSCLC : Analysis of long-term responders (LTRs) in the LUX-Lung (LL) 3, 6 and 7 trials
    In: Annals of Oncology Vol. 28 (2017) Nr. Suppl. 2,
  • Schreiber, Timm; Quinting, Theresa; Dittmer, Ulf; Fandrey, Joachim; Sutter, Kathrin
    Hypoxia-inducible factor 1α is essential for macrophage-mediated erythroblast proliferation in acute friend retrovirus infection
    In: Scientific Reports Vol. 7 (2017) art. no. 17236
  • Bäcker, Veronika; Cheung, Fung-Yi; Siveke, Jens; Fandrey, Joachim; Winning, Sandra
    Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis
    In: PLoS ONE Vol. 12 (2017) Nr. 12, pp. e0190074
  • Krzywinska, Ewelina; Kantari-Mimoun, Chahrazade; Kerdiles, Yann; Sobecki, Michal; Isagawa, Takayuki; Gotthardt, Dagmar; Castells, Magali; Haubold, Johannes; Millien, Corinne; Viel, Thomas; Tavitian, Bertrand; Takeda, Norihiko; Fandrey, Joachim; Vivier, Eric; Sexl, Veronika; Stockmann, Christian
    Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
    In: Nature Communications Vol. 8 (2017) pp. 1597
  • Prost-Fingerle, Katrin; Hoffmann, Mareike Daniela; Schützhold, Vera; Cantore, Miriam; Fandrey, Joachim
    Optical analysis of cellular oxygen sensing
    In: Experimental Cell Research Vol. 356 (2017) Nr. 2, pp. 122 - 127
  • Frede, Stilla; Stockmann, Christian; Winning, Sandra; Freitag, Patricia; Fandrey, Joachim
    Retraction: Hypoxia-Inducible Factor (HIF) 1α Accumulation and HIF Target Gene Expression Are Impaired after Induction of Endotoxin Tolerance
    In: The Journal of Immunology (JI) Vol. 199 (2017) Nr. 3, pp. 1206
  • Winning, Sandra; Fandrey, Joachim
    Dendritic Cells under Hypoxia : How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity
    In: Journal of Immunology Research (2016) pp. 5134329
  • Strasser, Katja; Lueckemann, Laura; Kluever, Verena; Thavaneetharajah, Sinthuya; Hoeber, Daniela; Bendix, Ivo; Fandrey, Joachim; Bertsche, Astrid; Felderhoff-Müser, Ursula
    Dose-dependent effects of levetiracetam after hypoxia and hypothermia in the neonatal mouse brain
    In: Brain Research Vol. 1646 (2016) pp. 116 - 124
  • Hoeber, Daniela; Sifringer, Marco; van de Looij, Yohan; Herz, Josephine; Sizonenko, Stéphane V; Kempe, Karina; Serdar, Meray; Palasz, Joanna; Hadamitzky, Martin; Endesfelder, Stefanie; Fandrey, Joachim; Felderhoff-Müser, Ursula; Bendix, Ivo
    Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury
    In: Oxidative Medicine and Cellular Longevity (2016) pp. 9247493
  • Görtz, Gina-Eva; Horstmann, Mareike; Aniol, Barbara; Reyes, Buena Delos; Fandrey, Joachim; Eckstein, Anja; Berchner-Pfannschmidt, Utta
    Hypoxia-Dependent HIF-1 Activation Impacts on Tissue Remodeling in Graves' Ophthalmopathy-Implications for Smoking
    In: The Journal of Clinical Endocrinology & Metabolism (JCEM) Vol. 101 (2016) Nr. 12, pp. 4834 - 4842
  • Flück, K.; Fandrey, Joachim; Breves, G; Winning, Sandra
    Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis
    In: Mucosal Immunology Vol. 9 (2016) Nr. 2, pp. 379 - 390
  • Schäfer, Simon; Franken, Lars; Adamzik, Michael; Schumak, Beatrix; Scherag, Andre; Engler, Andrea; Schönborn, Niels; Walden, Jennifer; Koch, Susanne; Baba, Hideo Andreas; Steinmann, Jörg; Westendorf, Astrid; Fandrey, Joachim; Bieber, Thomas; Kurts, Christian; Frede, Stilla; Peters, Jürgen; Limmer, Andreas
    Mitochondrial DNA : an endogenous trigger for immune paralysis
    In: Anesthesiology Vol. 124 (2016) Nr. 4, pp. 923 - 933
  • Flück, Katharina; Fandrey, Joachim
    Oxygen sensing in intestinal mucosal inflammation
    In: Pflügers Archiv: European Journal of Physiology Vol. 468 (2016) Nr. 1, pp. 77 - 84
  • Farsijani, Navid M; Liu, Qingdu; Kobayashi, Hanako; Davidoff, Olena; Sha, Feng; Fandrey, Joachim; Ikizler, T Alp; O'Connor, Paul M; Haase, Volker H
    Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin
    In: The Journal of Clinical Investigation (JCI) Vol. 126 (2016) Nr. 4, pp. 1425 - 1437
  • Klose, Ralph; Krzywinska, Ewelina; Castells, Magali; Gotthardt, Dagmar; Putz, Eva Maria; Kantari-Mimoun, Chahrazade; Chikdene, Naima; Meinecke, Anna-Katharina; Schrödter, Katrin; Helfrich, Iris; Fandrey, Joachim; Sexl, Veronika; Stockmann, Christian
    Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia
    In: Nature Communications Vol. 7 (2016) pp. 12528
  • Acker, Helmut; Schmidt-Rathjens, Claudia; Acker, Till; Fandrey, Joachim; Ehleben, Wilhelm
    Acupuncture-brain interactions as hypothesized by mood scale recordings
    In: Medical Hypotheses Vol. 85 (2015) Nr. 3, pp. 371 - 379
  • Fandrey, Joachim; Hallek, M
    Erythropoese : Physiologie, Pathophysiologie und Algorithmus zur Abklärung von Anämien
    In: Der Internist Vol. 56 (2015) Nr. 9, pp. 970 - 977
  • Otto, Teresa; Fandrey, Joachim
    Hypoxia induced gene expression: The specificity switch!
    In: Cell Cycle Vol. 14 (2015) Nr. 10, pp. 1491
  • Hülsemann, M. F.; Patz, Michaela; Beckmann, L.; Brinkmann, K.; Otto, Teresa; Fandrey, Joachim; Becker, Hans Jiro; Theurich, Sebastian; Von Bergwelt-Baildon, Michael S.; Pallasch, Christian Philipp; Zahedi, P.; Kashkar, Hamid; Reinhardt, Hans Christian; Hallek, Michael J.; Wendtner, Clemens Martin; Frenzel, Lukas P.
    Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia
    In: Leukemia Vol. 29 (2015) Nr. 4, pp. 981 - 984
  • Zeitouni, Nathalie E.; Fandrey, Joachim; Naim, Hassan Y.; von Köckritz-Blickwede, Maren
    Measuring oxygen levels in Caco-2 cultures
    In: Hypoxia Vol. 3 (2015) pp. 53 - 66
  • Maxwell, Perry; Melendez-Rodríguez, Florinda; Matchett, Kyle B.; Aragones, Julian; Ben-Califa, Nathalie; Jaekel, Heidelinde; Hengst, Ludger; Lindner, Herbert; Bernardini, Andre; Brockmeier, Ulf; Fandrey, Joachim; Grunert, Fritz; Oster, Howard S.; Mittelman, Moshe; El-Tanani, Mohamed; Thiersch, Markus; Schneider Gasser, Edith M.; Gassmann, Max; Dangoor, David; Cuthbert, Robert J.; Irvine, Alexandra; Jordan, Anne; Lappin, Terence; Thompson, John; Neumann, Drorit
    Novel antibodies directed against the human erythropoietin receptor : Creating a basis for clinical implementation
    In: British Journal of Haematology Vol. 168 (2015) Nr. 3, pp. 429 - 442
  • Otto, Teresa; Gellhaus, Alexandra; Lüschen, Navina; Scheidler, Jan; Bendix, Ivo; Dunk, Caroline; Wolf, Nadine; Lennartz, Klaus; Köninger, Angela; Schmidt, Markus; Kimmig, Rainer; Fandrey, Joachim; Winterhager, Elke
    Oxygen Sensitivity of Placental Trophoblast Connexins 43 and 46 : A Role in Preeclampsia?
    In: Journal of Cellular Biochemistry Vol. 116 (2015) Nr. 12, pp. 2924 - 2937
  • Wein, Frederik; Otto, Teresa; Lambertz, Pascal; Fandrey, Joachim; Hansmann, Martin-Leo; Küppers, Ralf
    Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis
    In: Haematologica / The Hematology Journal Vol. 100 (2015) Nr. 10, pp. 1320 - 1326
  • Kantari-Mimoun, Chahrazade; Castells, Magali; Klose, Ralph; Meinecke, Anna-Katharina; Lemberger, Ursula J.; Rautou, Pierre-Emmanuel; Pinot-Roussel, Helene; Badoual, Cecile; Schrödter, Katrin; Österreicher, Christoph H.; Fandrey, Joachim; Stockmann, Christian
    Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis
    In: Hepatology Vol. 61 (2015) Nr. 6, pp. 2042 - 2055
  • Fandrey, Joachim
    Rounding up the usual suspects in O2 sensing : CO, NO, and H2S!
    In: Science Signaling Vol. 8 (2015) Nr. 373, pp. fs10
  • Bernardini, Andre; Brockmeier, Ulf; Metzen, Eric; Berchner-Pfannschmidt, Utta; Harde, E.; Acker-Palmer, Amparo; Papkovsky, Dmitri B.; Acker, Helmut; Fandrey, Joachim
    Type I cell ROS kinetics under hypoxia in the intact mouse carotid body ex vivo : a FRET-based study
    In: American Journal of Physiology: Lung Cellular and Molecular Physiology Vol. 308 (2015) Nr. 1, pp. C61 - C67
  • Storti, Federica; Santambrogio, Sara; Crowther, Lisa M.; Otto, Teresa; Abreu-Rodríguez, Irene; Kaufmann, Muriel; Hu, Cheng-Jun; Dame, Christof; Fandrey, Joachim; Wenger, Roland H.; Hoogewijs, David
    A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression
    In: Haematologica / The Hematology Journal Vol. 99 (2014) Nr. 4, pp. e45 - e48
  • Funk, Kristina; Scheerer, Nina; Verhaegh, Rabea; Pütter, Carolin; Fandrey, Joachim; de Groot, Herbert
    Severe Blunt Muscle Trauma in Rats : Only Marginal Hypoxia in the Injured Area
    In: PLoS ONE Vol. 9 (2014) Nr. 10, pp. e111151
  • Franke, Kristin; Kalucka, Joanna; Mamlouk, Soulafa; Singh, Rashim Pal; Muschter, Antje; Weidemann, Alexander; Iyengar, Vasuprada; Jahn, Steffen; Wieczorek, Kathrin; Geiger, Kathrin; Muders, Michael; Sykes, Alex M.; Poitz, David M.; Ripich, Tatsiana; Otto, Teresa; Bergmann, Sybille; Breier, Georg; Baretton, Gustavo; Fong, Guo-Hua; Greaves, David R.; Bornstein, Stefan; Chavakis, Triantafyllos; Fandrey, Joachim; Gassmann, Max; Wielockx, Ben
    HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis
    In: Blood Vol. 121 (2013) Nr. 8, pp. 1436 - 1445
  • Fandrey, Joachim
    Highlight : sensing hypoxia in the cell and the organism
    In: Biological Chemistry Vol. 394 (2013) Nr. 4, pp. 433 - 434
  • Schäfer, Simon; Frede, Stilla; Winning, Sandra; Bick, Alexandra; Roshangar, Paktis; Fandrey, Joachim; Peters, Jürgen; Adamzik, Michael
    Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: Prospective observational clinical and cellular studies
    In: Anesthesiology Vol. 118 (2013) Nr. 6, pp. 1426 - 1436
  • Scheerer, Nina; Dehne, Nathalie; Stockmann, Christian; Swoboda, Sandra; Baba, Hideo Andreas; Neugebauer, Agnes; Johnson, Randall S.; Fandrey, Joachim
    Myeloid hypoxia-inducible factor-1α is essential for skeletal muscle regeneration in mice
    In: The Journal of Immunology (JI) Vol. 191 (2013) Nr. 1, pp. 407 - 414
  • Wiesweg, M.; Berchner-Pfannschmidt, Utta; Fandrey, Joachim; Petrat, Frank; de Groot, H.; Kirsch, Michael
    Rocket fuel for the quantification of S-nitrosothiols : highly specific reduction of S-nitrosothiols to thiols by methylhydrazine
    In: Free Radical Research Vol. 47 (2013) Nr. 2, pp. 104 - 115
  • Wobben, Regina; Hüsecken, Yvonne; Lodewick, Claudia; Gibbert, Kathrin; Fandrey, Joachim; Winning, Sandra
    Role of hypoxia inducible factor-1 α for interferon synthesis in mouse dendritic cells
    In: Biological Chemistry Vol. 394 (2013) Nr. 4, pp. 495 - 505
  • Adamzik, Michael; Schäfer, Simon; Frey, Ulrich; Becker, Arne; Kreuzer, Maximiliane; Winning, Sandra; Frede, Stilla; Steinmann, Jörg; Fandrey, Joachim; Zacharowski, Kai; Siffert, Winfried; Peters, Jürgen; Hartmann, Matthias
    The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.
    In: Anesthesiology Vol. 118 (2013) Nr. 1, pp. 123 - 133
  • Meinecke, Anna-Katharina; Nagy, Nadine; D'Amico Lago, Gabriela; Kirmse, Santina; Klose, Ralph; Schrödter, Katrin; Zimmermann, Annika; Helfrich, Iris; Rundqvist, Helene; Theegarten, Dirk; Anhenn, Olaf; Orian-Rousseau, Véronique; Johnson, Randall S.; Alitalo, Kari; Fischer, Jens W.; Fandrey, Joachim; Stockmann, Christian
    Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis
    In: Blood Vol. 119 (2012) Nr. 24, pp. 5931 - 5942
  • Schwartz, M.; Otto, Teresa; Brockmeier, U.; Lauterbach, S.; Metzen, Eric; Gulbins, Erich; Carpinteiro, Alexander; Scheerer, N.; Fandrey, Joachim
    Effects of nitric oxide on hematogenous metastasis
    In: American Journal of Hematology Vol. 87 (2012) Nr. 10, pp. E112 - E112
  • Pientka, Friederike Katharina; Hu, Jun; Schindler, Susann Gaby; Brix, Britta; Thiel, Anika; Jöhren, Olaf; Fandrey, Joachim; Berchner-Pfannschmidt, Utta; Depping, Reinhard
    Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling
    In: Journal of Cell Science Vol. 125 (2012) Nr. 21, pp. 5168 - 5176
  • Niecknig, Helene; Tug, Suzan; Reyes, Buena Delos; Kirsch, Michael; Fandrey, Joachim; Berchner-Pfannschmidt, Utta
    Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia
    In: Free Radical Research Vol. 46 (2012) Nr. 6, pp. 705 - 717
  • Wollenick, Kristin; Hu, Jun; Kristiansen, Glen; Schraml, Peter; Rehrauer, Hubert; Berchner-Pfannschmidt, Utta; Fandrey, Joachim; Wenger, Roland H.; Stiehl, Daniel P.
    Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling
    In: Nucleic Acids Research Vol. 40 (2012) Nr. 5, pp. 1928 - 1943
  • Fluck, K.; Breves, G.; Schäfer, Simon; Fandrey, Joachim; Winning, S.
    The Role of Hypoxia-Inducible Factors in Inflammatory Bowel Disease
    In: American Journal of Hematology Vol. 87 (2012) Nr. 10, pp. E102 - E102
  • Fandrey, Joachim
    Why not the liver instead of the kidney?
    In: Blood Vol. 120 (2012) Nr. 9, pp. 1760 - 1761
  • Dehne, Nathalie; Kerkweg, Uta; Flohe, Stefanie; Brüne, Bernhard; Fandrey, Joachim
    Activation of hypoxia-inducible factor 1 in skeletal muscle cells after exposure to damaged muscle cell debris
    In: Shock Vol. 35 (2011) Nr. 6, pp. 632 - 638
  • Wotzlaw, Christoph; Bernardini, André; Berchner-Pfannschmidt, Utta; Papkovsky, Dmitri; Acker, Helmut; Fandrey, Joachim
    Multifocal animated imaging of changes in cellular oxygen and calcium concentrations and membrane potential within the intact adult mouse carotid body ex vivo
    In: American Journal of Physiology: Cell Physiology Vol. 301 (2011) Nr. 2, pp. C266 - 71
  • Frede, Stilla; Freitag, Patricia; Geuting, Luise; Konietzny, Rebecca; Fandrey, Joachim
    Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC
    In: Blood Vol. 117 (2011) Nr. 18, pp. 4905 - 4914
  • Brockmeier, Ulf; Platzek, Corinna; Schneider, Kirsten; Patak, Pauline; Bernardini, André; Fandrey, Joachim; Metzen, Eric
    The Function of Hypoxia-Inducible Factor (HIF) Is Independent of the Endoplasmic Reticulum Protein OS-9
    In: PLoS ONE Vol. 6 (2011) Nr. 4, pp. e19151
  • Adamzik, Michael; Schaefer, S.; Frey, Ulrich; Becker, A.; Kreutzer, M.; Winning, S.; Frede, Stilla; Steinmann, Jörg; Fandrey, Joachim; Zacharowski, K.; Siffert, Winfried; Peters, Jürgen; Hartmann, Matthias
    The NFKB1 promoter polymorphism (94ins/delATTG) alters nuclear translocation of NF-KB1 in monocytes following lipopolysaccharide stimulation and is associated with increased mortality in sepsis
    In: Infection - A Journal of Infectious Disease Vol. 39 (2011) Nr. Suppl. 2, pp. 102
  • Winning, Sandra; Splettstoesser, Frank; Fandrey, Joachim; Frede, Stilla
    Acute Hypoxia Induces HIF-Independent Monocyte Adhesion to Endothelial Cells through Increased Intercellular Adhesion Molecule-1 Expression : The Role of Hypoxic Inhibition of Prolyl Hydroxylase Activity for the Induction of NF- B
    In: The Journal of Immunology (JI) Vol. 185 (2010) Nr. 3, pp. 1786 - 1793
  • Bernardini, A.; Wotzlaw, C.; Lipinski, H. G.; Fandrey, Joachim
    An Automated Real Time System for FRET Based Protein-Protein Interaction Analysis
    In: IFMBE Proceedings Vol. 25 (2010) pp. 1056 - 1058
  • Ruas, Jorge L.; Berchner-Pfannschmidt, Utta; Malik, Sohail; Gradin, Katarina; Fandrey, Joachim; Roeder, Robert G.; Pereira, Teresa; Poellinger, Lorenz
    Complex Regulation of the Transactivation Function of Hypoxia-inducible Factor-1α by Direct Interaction with Two Distinct Domains of the CREB-binding Protein/p300
    In: The Journal of Biological Chemistry (JBC) Vol. 285 (2010) Nr. 4, pp. 2601 - 2609
  • Benko, Tamas; Frede, Stilla; Gu, Yanli; Best, Jan; Baba, Hideo Andreas; Schlaak, Jörg Friedrich; De Groot, Herbert; Fandrey, Joachim; Rauen, Ursula
    Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat
    In: Journal of Investigative Surgery Vol. 23 (2010) Nr. 1, pp. 12 - 20
  • Gellhaus, Alexandra; Wotzlaw, Christoph; Otto, Teresa; Fandrey, Joachim; Winterhager, Elke
    More insights into the CCN3/connexin43 interaction complex and its role for signaling
    In: Journal of Cellular Biochemistry Vol. 110 (2010) Nr. 1, pp. 129 - 140
  • Wotzlaw, Christoph; Gneuss, Silke; Konietzny, Rebecca; Fandrey, Joachim
    Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software
    In: PMC Biophysics Vol. 3 (2010) Nr. 1,
  • Berchner-Pfannschmidt, Utta; Tug, Suzan; Kirsch, Michael; Fandrey, Joachim
    Oxygen-sensing under the influence of nitric oxide
    In: Cellular Signalling Vol. 22 (2010) Nr. 3, pp. 349 - 356
  • Berchner-Pfannschmidt, Utta; Tug, Suzan; Hu, Jun; Reyes, Buena Delos; Fandrey, Joachim; Kirsch, Michael
    Role of N-acetyl-N-nitroso-tryptophan as nitric oxide donor in the modulation of HIF-1-dependent signaling
    In: Biological Chemistry Vol. 391 (2010) Nr. 5, pp. 533 - 540
  • Scheerer, N.; Dünker, Nicole; Imagawa, S.; Yamamoto, M.; Suzuki, N.; Fandrey, Joachim
    The anemia of the newborn induces erythropoietin expression in the developing mouse retina
    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology Vol. 299 (2010) Nr. 1, pp. R111 - R118
  • Schmitz, Klaus Jürgen; Müller, Carmen Ina; Reis, Henning; Alakus, Hakan; Winde, Günther; Baba, Hideo Andreas; Wohlschläger, Jeremias; Jasani, Bharat; Fandrey, Joachim; Schmid, Kurt Werner
    Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma
    In: International Journal of Colorectal Disease Vol. 24 (2009) Nr. 11, pp. 1287 - 1296
  • Severino, Anna; Campioni, Mara; Straino, Stefania; Salloum, Fadi N.; Schmidt, Nina; Herbrand, Ulrike; Frede, Stilla; Toietta, Gabriele; Rocco, Giuliana Di; Bussani, Rossana; Silvestri, Furio; Piro, Maddalena; Liuzzo, Giovanna; Biasucci, Luigi M.; Mellone, Pasquale; Feroce, Florinda; Capogrossi, Maurizio; Baldi, Feliciano; Fandrey, Joachim; Ehrmann, Michael; Crea, Filippo; Abbate, Antonio; Baldi, Alfonso
    Identification of Protein Disulfide Isomerase as a Cardiomyocyte Survival Factor in Ischemic Cardiomyopathy
    In: Journal of the American College of Cardiology (JACC) Vol. 50 (2007) Nr. 11, pp. 1029 - 1037
  • Schade, Fritz Ulrich; Fandrey, Joachim; de Groot, Herbert
    Schwierige Traumabehandlung : Immun- und Stoffwechselmodulation durch schweres Gewebstrauma
    In: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, pp. 48 - 59
  • Dürig, Jan; Nückel, Holger; Cremer, M.; Führer, A.; Halfmeyer, K.; Fandrey, Joachim; Möröy, Tarik; Klein-Hitpaß, Ludger; Dührsen, Ulrich
    ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia
    In: Leukemia Vol. 17 (2003) Nr. 12, pp. 2426 - 2434
  • Stolze, I.; Berchner-Pfannschmidt, Utta; Freitag, P.; Wotzlaw, C.; Rössler, J.; Frede, Stilla; Acker, H.; Fandrey, Joachim
    Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells
    In: Blood Vol. 100 (2002) Nr. 7, pp. 2623 - 2628
  • Prefaces/Postfaces

  • Bie, P.; Brandes, R.P.; Deuchars, S.A.; Eisner, D.A.; Fandrey, Joachim; Hecker, M.; Louch, W.E.; Taira, T.; Yilmaz, B.
    Bringing European physiologists together
    In: Acta Physiologica Vol. 222 (2018) Nr. 4, pp. e13043
  • Fandrey, Joachim
    Membrane traffic control by hypoxia
    In: Acta Physiologica Vol. 221 (2017) Nr. 1, pp. 8 - 10
  • Reviews

  • Acker, Helmut; Fandrey, Joachim
    Carotid body physiology meets cytochrome c oxidase crystallography Commentary to Ortega-Sáenz P, López-Barneo J. Physiology of the Carotid Body: From Molecules to Disease. Annu Rev Physiol 82: 127–149, 2020. Torres-Torrelo H, Ortega-Sáenz P, Gao L, López-Barneo J. Lactate sensing mechanisms in arterial chemoreceptor cells. Nat Commun 12: 4166, 2021
    In: Pflügers Archiv: European Journal of Physiology Vol. 474 (2022) Nr. 2, pp. 187 - 189
  • Abstracts

  • Post, T.; de Gioannis, R.; Wittkowski, M.; Schoenberger, T.; Fandrey, Joachim; Elmenhorst, E. M.; Aeschbach, D.
    Resetting of the circadian rhythm of melatonin by exposure to moderate hypoxia in humans
    In: Journal of Sleep Research Vol. 31 (2022) Nr. Suppl. 1, O151/P340
  • Becker, Katrin; Jaegers, J.; Fandrey, Joachim; Gulbins, Erich; Ferenz, Katja;
    Development of sphingosine-coupled oxygen carriers as novel drugs for treating pneumonia
    98th Meeting of the German Physiological Society, 30 September ‐ 2 October 2019, Ulm, Germany,
    In: Acta Physiologica Vol. 227 (2019) Nr. S719, B 04-10
  • Moulouel, Boualem; Houamel, Dounia; Fandrey, Joachim; Vaulant, Sophie; Puy, Herve; Gouya, Laurent; Beaumont, Carole; Karim, Zoubida
    Renal erythropoietin production is impaired with iron overload and hepcidin loss
    In: American Journal of Hematology Vol. 88 (2013) Nr. 5, pp. E142 - E143
  • Book articles / Proceedings papers

  • Schützhold, Vera; Fandrey, Joachim; Prost-Fingerle, Katrin
    Fluorescence lifetime imaging microscopy (FLIM) as a tool to investigate hypoxia-induced protein-protein interaction in living cells
    In: Hypoxia: Methods and Protocols / Huang, L. Eric (Eds.) 2018, pp. 45 - 53
  • Hu, Jun; Bernardini, André; Fandrey, Joachim
    Optical analysis of hypoxia inducible factor (HIF)-1 complex assembly : Imaging of cellular oxygen sensing
    In: Hypoxia: Translation in Progress / Roach, Robert C; Hackett, Peter H.; Wagner, Peter D. (Eds.) 2016, pp. 247 - 258
  • Bernardini, Andre; Brockmeier, Ulf; Metzen, Eric; Berchner-Pfannschmidt, Utta; Harde, Eva; Acker-Palmer, Amparo; Papkovsky, Dmitri; Acker, Helmut; Fandrey, Joachim
    Measurement of ROS levels and membrane potential dynamics in the intact carotid body ex vivo
    In: Arterial Chemoreceptors in Physiology and Pathophysiology / XVIIIth Meeting of the International Society for Arterial Chemoreception ; Leeds, June 30 - July 3, 2014 / Peers, Chris; Kumar, Prem; Wyatt, Christopher; Gauda, Estelle; Nurse, Colin A.; Prabhakar, Nanduri (Eds.) 2015, pp. 55 - 59
  • Bernardini, André; Wotzlaw, Christoph; Lipinski, Hans-Gerd; Fandrey, Joachim
    An automated real time microscopy system for analysis of Fluorescence Resonance Energy Transfer
    In: Optics, photonics, and digital technologies for multimedia applications / Schelkens, Peter; SPIE Photonics Europe Conference on Optics, Photonics, and Digital Technologies for Multimedia Applications, 12 - 15 April 2010, Brussels, Belgium 2010
  • Ehleben, Wilhelm; Fandrey, Joachim; Acker, Helmut
    Detection and function of mitochondrial and non mitochondrial heme proteins in oxygen sensing tissues
    In: Mitochondria: structure, functions, and dysfunctions / Svensson, Oliver L. 2010, pp. 683 - 707
  • Wotzlaw, Christoph; Fandrey, Joachim
    Monitoring of cellular responses to hypoxia
    In: Live Cell Imaging: Methods and Protocols / Papkovsky, Dmitri B. (Eds.) 2010, pp. 243 - 255
  • Fandrey, Joachim
    Oxygen- or redox-dependent regulation : The role of hydrogen peroxide in the regulation of erythropoietin gene expression
    In: Oxygen sensing: responses and adaptation to hypoxia / Lahiri, Sukhamay; Semenza, Gregg L.; Prabhakar, Nanduri R. (Eds.) 2003, pp. 65 - 81
  • Lectures

  • Fandrey, Joachim
    Wie unsere Zellen im Körper Sauerstoffmangel erkennen
    Duisburg, Essen (2023)
    (Die Kleine Form ; WS 2023/24)