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Cyrus Khandanpour

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  • , Zentrum für Innere Medizin

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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Frenking, Jan H.; Riedhammer, Christine; Teipel, Raphael; Bassermann, Florian; Besemer, Britta; Bewarder, Moritz; Braune, Jan; Brioli, Annamaria; Brunner, Franziska; Dampmann, Maria; Fenk, Roland; Gezer, Deniz N.; Goldman-Mazur, Sarah; Hanoun, Christine; Högner, Marion; Khandanpour, Cyrus; Kolditz, Katja; Kos, Igor; Krönke, Jan; Kull, Miriam; Landrin, Valentine; Leitner, Theo; Merz, Maximilian; von Metzler, Ivana; Michel, Christian S.; Müller-Tidow, Carsten; Theurich, Sebastian; Trautmann-Grill, Karolin; Wäsch, Ralph; Zukovs, Romans; Hänel, Mathias; Rasche, Leo; Raab, Marc S.
    A German multicenter real-world analysis of talquetamab in 138 patients with relapsed/refractory multiple myeloma
    In: HemaSphere: Open Access Journal of the European Hematology Association, Jg. 9, 2025, Nr. 4, e70114
    DOI (Open Access)
  • Wegner, Franz; Sieren, Malte Maria; Grasshoff, Hanna; Berkel, Lennart; Rowold, Christoph; Röttgerding, Marcel Philipp; Khalil, Soleiman; Mogadas, Sam; Nensa, Felix; Hosch, René; Riemekasten, Gabriela; Hamm, Anna Franziska; von Bubnoff, Nikolas; Barkhausen, Jörg; Kloeckner, Roman; Khandanpour, Cyrus; Leitner, Theo
    AI-based body composition analysis of CT data has the potential to predict disease course in patients with multiple myeloma
    In: Scientific Reports, Jg. 15, 2025, Nr. 1, 26455
    DOI (Open Access)
  • Maulhardt, Markus; Call, Simon; Boyadzhiev, Hristo; Albici, Anca Maria; Hörster, Keven; Boquoi, Amelie; Janjetovic, Snjezana; Ossami Saidy, Anna; Teichert, Marcel; Brioli, Annamaria; Schultze-Florey, Christian; Heidel, Florian; Schindler, Philipp; Schub, Natalie; Aydilek, Enver; Stelljes, Matthias; Daskalakis, Michael; Krekeler, Carolin; Hasenkamp, Justin; Khandanpour, Cyrus; Bacher, Ulrike; Reinhardt, Hans Christian; Lenz, Georg; Stölzel, Friedrich; Pabst, Thomas; von Tresckow, Bastian; Wulf, Gerald; Berning, Philipp; Shumilov, Evgenii
    Efficacy of idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma and prior central nervous system manifestation : A multicenter real-world analysis
    In: HemaSphere: Open Access Journal of the European Hematology Association, Jg. 9, 2025, Nr. 8, e70192
    DOI (Open Access)
  • Vorwerk, Jan; Liu, Longlong; Stadler, Theresa Helene; Frank, Daria; Ahmed, Helal Mohammed Mohammed; Patnana, Pradeep Kumar; Kebenko, Maxim; Dazert, Eva; Opalka, Bertram; von Bubnoff, Nikolas; Khandanpour, Cyrus
    Germline Single-Nucleotide Polymorphism GFI1-36N Causes Alterations in Mitochondrial Metabolism and Leads to Increased ROS-Mediated DNA Damage in a Murine Model of Human Acute Myeloid Leukemia
    In: Biomedicines, Jg. 13, 2025, Nr. 1, 107
    DOI (Open Access)
  • Merz, Maximilian; Albici, Anca-Maria; von Tresckow, Bastian; Rathje, Kristin; Fenk, Roland; Holderried, Tobias; Müller, Fabian; Tovar, Natalia; Oliver-Cáldes, Aina; Vucinic, Vladan; Kharboutli, Soraya; Bärmann, Ben-Niklas; Ayuk, Francis; Platzbecker, Uwe; Stölzel, Friedrich; Schub, Nathalie; Schmitz, Friederike; Fandrei, David; Born, Patrick; Khandanpour, Cyrus; Hanoun, Christine; Hörster, Keven; Teichert, Marcel; Jeker, Barbara; Hoffmann, Michele; Kröger, Nicolaus; de Larrea, Carlos Fernández; Pabst, Thomas; Gagelmann, Nico
    Idecabtagene vicleucel or ciltacabtagene autoleucel for relapsed or refractory multiple myeloma : An international multicenter study
    In: HemaSphere: Open Access Journal of the European Hematology Association, Jg. 9, 2025, Nr. 1, e70070
    DOI (Open Access)
  • Ahmed, Helal; Patnana, Pradeep Kumar; Al-Matary, Yahya S.; Fiori, Maren; Vorwerk, Jan; Ahmad, Marah H.; Dazert, Eva; Oelschläger, Lorenz; Künstner, Axel; Opalka, Bertram; von Bubnoff, Nikolas; Khandanpour, Cyrus
    Impact of Acute Myeloid Leukemia Cells on the Metabolic Function of Bone Marrow Mesenchymal Stem Cells
    In: International Journal of Molecular Sciences (IJMS), Jg. 26, 2025, Nr. 17, 8301
    DOI (Open Access)
  • Merz, Maximilian; Dima, Danai; Hashmi, Hamza; Ahmed, Nausheen; Stölzel, Friedrich; Holderried, Tobias A. W.; Fenk, Roland; Müller, Fabian; Tovar, Natalia; Oliver-Cáldes, Aina; Rathje, Kristin; Davis, James A.; Fandrei, David; Vucinic, Vladan; Kharboutli, Soraya; Baermann, Ben-Niklas; Ayuk, Francis; Platzbecker, Uwe; Albici, Anca-Maria; Schub, Nathalie; Schmitz, Friederike; Shune, Leyla; Khouri, Jack; Anwer, Faiz; Raza, Shahzad; McGuirk, Joseph; Mahmoudjafari, Zahra; Green, Kimberly; Khandanpour, Cyrus; Teichert, Marcel; Jeker, Barbara; Hoffmann, Michele; Kröger, Nicolaus; von Tresckow, Bastian; de Larrea, Carlos Fernández; Pabst, Thomas; Abdallah, Al-Ola; Gagelmann, Nico
    Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy
    In: Blood Cancer Journal, Jg. 14, 2024, Nr. 1, 214
    DOI (Open Access)
  • Kamili, Abdulaziz; Ahmadi, Paymon; Leypoldt, Lisa; Marquard, Franziska; Schaefers, Christoph; Kosch, Ricardo; Peters, Frederik; Kusche, Henrik; Zamrik, Tanja; Hanoun, Christine; Seib, Maximilian; Shumilov, Evgenii; Leitner, Theo; Khandanpour, Cyrus; Bokemeyer, Carsten; Weisel, Katja; Ghandili, Susanne
    Multiple myeloma in the young : Insights on prognosis, clinical features and treatment outcome derived from nationwide German registry data and a nested multicenter sample
    In: Haematologica / The Hematology Journal, Jg. 109, 2024, Nr. 11, S. 3795 – 3799
    DOI (Open Access)
  • Sun, Kaiyan; Jin, Ling; Karolová, Jana; Vorwerk, Jan; Hailfinger, Stephan; Opalka, Bertram; Zapukhlyak, Myroslav; Lenz, Georg; Khandanpour, Cyrus
    Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma
    In: Cancers, Jg. 15, 2023, Nr. 8, 2373
    DOI (Open Access)
  • Xie, Xiaoqing; Patnana, Pradeep Kumar; Frank, Daria; Schütte, Judith; Al-Matary, Yahya; Künstner, Axel; Busch, Hauke; Ahmed, Helal; Liu, Longlong; Engel, Daniel Robert; Dührsen, Ulrich; Rosenbauer, Frank; Von Bubnoff, Nikolas; Lenz, Georg; Khandanpour, Cyrus
    Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs
    In: Frontiers in Cell and Developmental Biology, Jg. 11, 2023, 866847
    DOI (Open Access)
  • Patnana, Pradeep Kumar; Liu, Longlong; Frank, Daria; Nimmagadda, Subbaiah Chary; Behrens, Matthias; Ahmed, Helal; Xie, Xiaoqing; Liebmann, Marie; Wei, Lanying; Gerdemann, Andrea; Thivakaran, Aniththa; Humpf, Hans-Ulrich; Klotz, Luisa; Dugas, Martin; Varghese, Julian; Trajkovic-Arsic, Marija; Siveke, Jens T.; Hanenberg, Helmut; Opalka, Bertram; Dührsen, Ulrich; Reinhardt, Hans Christian; Guenther, Ulrich; von Bubnoff, Nikolas; Khandanpour, Cyrus
    Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cells
    In: British Journal of Haematology, Jg. 202, 2023, Nr. 5, S. 1033 – 1048
    DOI (Open Access)
  • Frank, Daria; Patnana, Pradeep Kumar; Vorwerk, Jan; Mao, Lianghao; Gopal, Lavanya Mokada; Jung, Noelle; Hennig, Thorben; Ruhnke, Leo; Frenz, Joris Maximillian; Kuppusamy, Maithreyan; Autry, Robert; Wei, Lanying; Sun, Kaiyan; Mohammed Ahmed, Helal Mohammed; Künstner, Axel; Busch, Hauke; Müller, Heiko; Hutter, Stephan; Hoermann, Gregor; Liu, Longlong; Xie, Xiaoqing; Al-Matary, Yahya; Nimmagadda, Subbaiah Chary; Charles Cano, Fiorella; Heuser, Michael; Thol, Felicitas; Göhring, Gudrun; Steinemann, Doris; Thomale, Jürgen; Leitner, Theo; Fischer, Anja; Rad, Roland; Röllig, Christoph; Altmann, Heidi; Kunadt, Desiree; Berdel, Wolfgang E.; Hüve, Jana; Neumann, Felix; Klingauf, Jürgen; Calderon, Virginie; Opalka, Bertram; Dührsen, Ulrich; Rosenbauer, Frank; Dugas, Martin; Varghese, Julian; Reinhardt, Hans Christian; von Bubnoff, Nikolas; Möröy, Tarik; Lenz, Georg; Batcha, Aarif M. N.; Giorgi, Marianna; Selvam, Murugan; Wang, Eunice; McWeeney, Shannon K.; Tyner, Jeffrey W.; Stölzel, Friedrich; Mann, Matthias; Jayavelu, Ashok Kumar; Khandanpour, Cyrus
    Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy
    In: Blood, Jg. 142, 2023, Nr. 25, S. 2175 – 2191
    DOI (Open Access)
  • Goldschmidt, Hartmut; Mai, Elias K.; Bertsch, Uta; Fenk, Roland; Nievergall, Eva; Tichy, Diana; Besemer, Britta; Dürig, Jan; Schroers, Roland; von Metzler, Ivana; Hänel, Mathias; Mann, Christoph; Asemissen, Anne M.; Heilmeier, Bernhard; Weinhold, Niels; Huhn, Stefanie; Kriegsmann, Katharina; Luntz, Steffen P.; Holderried, Tobias A W; Trautmann-Grill, Karolin; Gezer, Deniz; Klaiber-Hakimi, Maika; Müller, Martin; Khandanpour, Cyrus; Knauf, Wolfgang; Scheid, Christof; Munder, Markus; Geer, Thomas; Riesenberg, Hendrik; Thomalla, Jörg; Hoffmann, Martin; Raab, Marc S.; Salwender, Hans J.; Weisel, Katja C.; Ziske, Carsten; German-Speaking Myeloma Multicenter Group (GMMG) HD7 investigators (Hrsg.)
    Addition of isatuximab to lenalidomide, bortezomib, and dexamethasone as induction therapy for newly diagnosed, transplantation-eligible patients with multiple myeloma (GMMG-HD7) : Part 1 of an open-label, multicentre, randomised, active-controlled, phase 3 trial
    In: The Lancet Haematology, Jg. 9, 2022, Nr. 11, S. e810 – e821
    DOI
  • Xie, Xiaoqing; Frank, Daria; Patnana, Pradeep Kumar; Schütte, Judith; Al‐matary, Yahya; Liu, Longlong; Wei, Lanying; Dugas, Martin; Varghese, Julian; Nimmagadda, Subbaiah Chary; Khandanpour, Cyrus
    Curcumin as an epigenetic therapeutic agent in myelodysplastic syndromes (Mds)
    In: International Journal of Molecular Sciences (IJMS), Jg. 23, 2022, Nr. 1, 411
    DOI (Open Access)
  • Ahmed, Helal Mohammed Mohammed; Nimmagadda, Subbaiah Chary; Al-Matary, Yahya S.; Fiori, Maren; May, Tobias; Frank, Daria; Patnana, Pradeep Kumar; Récher, Christian; Schliemann, Christoph; Mikesch, Jan-Henrik; Koenig, Thorsten; Rosenbauer, Frank; Hartmann, Wolfgang; Tuckermann, Jan; Dührsen, Ulrich; Lanying, Wei; Dugas, Martin; Opalka, Bertram; Lenz, Georg; Khandanpour, Cyrus
    Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells
    In: British Journal of Haematology, Jg. 196, 2022, Nr. 4, S. 995 – 1006
    DOI (Open Access)
  • Liu, Longlong; Patnana, Pradeep Kumar; Xie, Xiaoqing; Frank, Daria; Nimmagadda, Subbaiah Chary; Su, Minhua; Zhang, Donghua; Koenig, Thorsten; Rosenbauer, Frank; Liebmann, Marie; Klotz, Luisa; Xu, Wendan; Vorwerk, Jan; Neumann, Felix; Hüve, Jana; Unger, Andreas; Okun, Jürgen Günther; Opalka, Bertram; Khandanpour, Cyrus
    GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia
    In: Leukemia, Jg. 36, 2022, Nr. 9, S. 2196 – 2207
    DOI (Open Access)
  • Liu, Longlong; Patnana, Pradeep Kumar; Xie, Xiaoqing; Frank, Daria; Nimmagadda, Subbaiah Chary; Rosemann, Annegret; Liebmann, Marie; Klotz, Luisa; Opalka, Bertram; Khandanpour, Cyrus
    High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid Leukemia
    In: Cancers, Jg. 14, 2022, Nr. 3, 486
    DOI, Online Volltext (Open Access)
  • Vorwerk, Jan; Sun, Kaiyan; Frank, Daria; Neumann, Felix; Hüve, Jana; Budde, Paulina Marie; Liu, Longlong; Xie, Xiaoqing; Patnana, Pradeep Kumar; Ahmed, Helal Mohammed Mohammed; Opalka, Bertram; Lenz, Georg; Jayavelu, Ashok Kumar; Khandanpour, Cyrus
    Presence of the GFI1-36N single nucleotide polymorphism enhances the response of MLL-AF9 leukemic cells to CDK4/6 inhibition
    In: Frontiers in Oncology, Jg. 12, 2022, 903691
    DOI (Open Access)
  • Fraszczak, Jennifer; Vadnais, Charles; Rashkovan, Marissa; Ross, Julie; Beauchemin, Hugues; Chen, Riyan; Grapton, Damien; Khandanpour, Cyrus; Möröy, Tarik
    Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice
    In: Leukemia, Jg. 33, 2019, Nr. 1, S. 110 – 121
    DOI, Online Volltext (Open Access)
  • Vadnais, Charles; Chen, Riyan; Fraszczak, Jennifer; Yu, Zhenbao; Boulais, Jonathan; Pinder, Jordan; Frank, Daria; Khandanpour, Cyrus; Hébert, Josée; Dellaire, Graham; Côté, Jean-François; Richard, Stéphane; Orthwein, Alexandre; Drobetsky, Elliot; Möröy, Tarik
    GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.
    In: Nature Communications, Jg. 9, 2018, S. 1418
    DOI (Open Access)
  • Marneth, Anna E.; Botezatu, Lacramioara; Hönes, Judith M.; Israël, Jimmy C. L.; Schütte, Judith; Vassen, Lothar; Lams, Robert F.; Bergevoet, Saskia M.; Groothuis, Laura; Mandoli, Amit; Martens, Joost H. A.; Huls, Gerwin; H.jansen, Joop; Dührsen, Ulrich; Berg, Tobias; Möröy, Tarik; Wichmann, Christian; Lo, Mia-Chia; Zhang, Dong-Er; Van Der Reijden, Bert A.; Khandanpour, Cyrus
    GFI1 is required for RUNX1/ETO positive acute myeloid leukemia
    In: Haematologica / The Hematology Journal, Jg. 103, 2018, Nr. 9, S. e395 – e399
    DOI (Open Access)
  • Thivakaran, Aniththa; Botezatu, Lacramioara; Hönes, Judith M.; Schütte, Judith; Vassen, Lothar; Al-Matary, Yahya S.; Patnana, Pradeep; Zeller, Amos; Heuser, Michael; Thol, Felicitas; Gabdoulline, Razif; Olberding, Nadine; Frank, Daria; Suslo, Marina; Köster, Renata; Lennartz, Klaus; Görgens, Andre; Giebel, Bernd; Opalka, Bertram; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi1b : A key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome
    In: Haematologica / The Hematology Journal, Jg. 103, 2018, Nr. 4, S. 614 – 625
    DOI (Open Access)
  • Hönes, Judith M.; Thivakaran, Aniththa; Botezatu, Lacramioara; Patnana, Pradeep; Castro, Symone Vitoriano da Conceição; Al-Matary, Yahya S.; Schütte, Judith; Fischer, Karen B. I.; Vassen, Lothar; Görgens, André; Dührsen, Ulrich; Giebel, Bernd; Khandanpour, Cyrus
    Enforced GFI1 expression impedes human and murine leukemic cell growth.
    In: Scientific Reports, Jg. 7, 2017, S. 15720
    DOI (Open Access)
  • Thivakaran, A.; Botezatu, L.; Hönes, J.; Al-Matary, Y.; Schütte, Jochen; Patnana, P. K.; Koester, R.; Opalka, Bertram; Dührsen, Ulrich; Khandanpour, Cyrus
    GFI1B-A novel oncosuppressor which restricts number of leukemic stem stells
    In: Haematologica / The Hematology Journal, Jg. 102, 2017, Nr. Suppl. 2, S. 204 – 204
  • Al-Matary, Y.; Botezatu, L.; Thivakaran, A.; Köster, R.; Schütte, Jochen; Göthert, Joachim Rudolf; Dührsen, Ulrich; Opalka, Bertram; Khandanpour, Cyrus
    Growth factor independence 1 (GFI !) regulates the AML supporting function of mesenchymal stromal cells
    In: Haematologica / The Hematology Journal, Jg. 102, 2017, Nr. Suppl. 2, S. 459 – 459
  • Weidner, H.; Rauner, M.; Trautmann, F.; Schmitt, J.; Balaian, E.; Mies, A.; Helas, S.; Baschant, U.; Khandanpour, Cyrus; Bornhäuser, M.; Hofbauer, L.C.; Platzbecker, U.
    Myelodysplastic syndromes and bone loss in mice and men
    In: Leukemia, Jg. 31, 2017, Nr. 4, S. 1003 – 1007
    DOI
  • Latteyer, Sören; Möller, Lars; Führer, Dagmar; Schmid, Kurt Werner; Pöppel, Thorsten; Khandanpour, Cyrus; Klein-Hitpaß, Ludger; Zwanziger, Denise
    A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A
    In: The Journal of Clinical Endocrinology & Metabolism (JCEM), Jg. 101, 2016, Nr. 3, S. 1016 – 1022
    DOI (Open Access)
  • Al-Matary, Yahya S; Botezatu, Lacramioara; Opalka, Bertram; Hönes, Judith M; Lams, Robert F; Thivakaran, Aniththa; Schütte, Judith; Köster, Renata; Lennartz, Klaus; Schroeder, Thomas; Haas, Rainer; Dührsen, Ulrich; Khandanpour, Cyrus
    Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner
    In: Haematologica / The Hematology Journal, Jg. 101, 2016, Nr. 10, S. 1216 – 1227
    DOI (Open Access)
  • Weidner, H.; Rauner, M.; Bulycheva, E.; Khandanpour, Cyrus; Bornhauser, M.; Hofbauer, L. C.; Platzbecker, U.
    Bone homeostasis is altered in a mouse model of myelodysplastic syndrome
    In: Oncology Research and Treatment, Jg. 39, 2016, Nr. Suppl. 3, S. 123 – 123
  • Weidner, H.; Rauner, M.; Bulycheva, E.; Khandanpour, Cyrus; Bornhauser, M.; Hofbauer, L. C.; Platzbecker, U.
    Bone homeostasis is significantly altered in a myelodysplastic syndrome mouse model
    In: Haematologica / The Hematology Journal, Jg. 101 1, 2016, S. 493 – 493
    (Open Access)
  • Botezatu, Lacramioara; Michel, Lars C; Helness, Anne; Vadnais, Charles; Makishima, Hideki; Hönes, Judith M; Robert, François; Vassen, Lothar; Thivakaran, Aniththa; Al-Matary, Yahya; Lams, Robert F; Schütte, Judith; Giebel, Bernd; Görgens, André; Heuser, Michael; Medyouf, Hind; Maciejewski, Jaroslaw; Dührsen, Ulrich; Möröy, Tarik; Khandanpour, Cyrus
    Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML
    In: Experimental Hematology, Jg. 44, 2016, Nr. 8, S. 713 – 726.e14
    DOI (Open Access)
  • Geyh, S; Rodríguez-Paredes, M; Jäger, P; Khandanpour, Cyrus; Cadeddu, R-P; Gutekunst, J; Wilk, C M; Fenk, R; Zilkens, C; Hermsen, D; Germing, U; Kobbe, G; Lyko, F; Haas, R; Schröder, Tobias
    Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia
    In: Leukemia, Jg. 30, 2016, Nr. 3, S. 683 – 691
    DOI
  • Hönes, J M; Botezatu, L; Helness, A; Vadnais, C; Vassen, L; Robert, F; Hergenhan, S M; Thivakaran, A; Schütte, J; Al-Matary, Y S; Lams, R F; Fraszscak, J; Makishima, H; Radivoyevitch, T; Przychodzen, B; da Conceição Castro, S V; Görgens, A; Giebel, Bernd; Klein-Hitpaß, Ludger; Lennartz, K; Heuser, M; Thiede, C; Ehninger, G; Dührsen, Ulrich; Maciejewski, J; Möröy, T; Khandanpour, Cyrus
    GFI1 as a novel prognostic and therapeutic factor for AML/MDS
    In: Leukemia, Jg. 30, 2016, Nr. 6, S. 1237 – 1245
    DOI
  • Botezatu, Lacramioara; Michel, Lars; Makishima, Hideki; Schroeder, Thomas; Germing, Ulrich; Haas, Rainer; Van der Reijden, Bert; Marneth, Anne E.; Bergevoet, Saskia M.; Jansen, Joop H.; Przychodzen, Bartlomiej; Wlodarski, Marcin; Niemeyer, Charlotte; Platzbecker, Uwe; Ehninger, Gerhard; Unnikrishnan, Ashwin; Beck, Dominik; Pimanda, John; Hellström-Lindberg, Eva; Malcovati, Luca; Boultwood, Jacqueline; Pellagatti, Andrea; Papaemmanuil, Elli; Le Coutre, Philipp; Kaeda, Jaspal; Opalka, Bertram; Möröy, Tarik; Dührsen, Ulrich; Maciejewski, Jaroslaw; Khandanpour, Cyrus
    GFI136N as a therapeutic and prognostic marker for myelodysplastic syndrome
    In: Experimental Hematology, Jg. 44, 2016, Nr. 7, S. 590 – 595.e1
    DOI (Open Access)
  • Gassa, Asmae; Kalkavan, Halime; Jian, Fu; Duhan, Vikas; Khairnar, Vishal; Shaabani, Namir; Honke, Nadine; Carpinteiro, Alexander; Botezatu, Lacramioara; Crivello, Pietro; Dolff, Sebastian; Ferencik, Stanislav; Häussinger, Dieter; Khandanpour, Cyrus; Fleischhauer, Katharina; Witzke, Oliver; Wahlers, Thorsten; Hardt, Cornelia; Lang, Philipp A; Lang, Karl S.
    High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model
    In: Cellular Physiology and Biochemistry, Jg. 38, 2016, Nr. 4, S. 1343 – 1353
    DOI (Open Access)
  • Fraszczak, J.; Chen, R. Y.; Rashkovan, M.; Vadnais, C.; Khandanpour, Cyrus; Moroy, T.
    Low GFI1 expression level drive the development of acute myeloid leukemia and fatal myeloproliferative neoplasia by blocking differentiation and P53-mediated apoptosis
    In: Experimental Hematology, Jg. 44 1, 2016, Nr. 9, S. 71 – S71
    DOI
  • Fraszczak, Jennifer; Helness, Anne; Chen, Riyan; Vadnais, Charles; Robert, François; Khandanpour, Cyrus; Möröy, Tarik
    Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1
    In: PLoS ONE, Jg. 11, 2016, Nr. 7, S. e0160344
    DOI (Open Access)
  • Duhan, Vikas; Khairnar, Vishal; Friedrich, Sarah-Kim; Zhou, Fan; Gassa, Asmae; Honke, Nadine; Shaabani, Namir; Gailus, Nicole; Botezatu, Lacramioara; Khandanpour, Cyrus; Dittmer, Ulf; Haüssinger, Dieter; Recher, Mike; Hardt, Cornelia; Lang, Philipp A.; Lang, Karl S.
    Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8 + T-cell priming and viral control
    In: Scientific Reports, Jg. 6, 2016, 19191
    DOI (Open Access)
  • Khandanpour, Cyrus; Dührsen, Ulrich; Marneth, A.; Michel, L.; Ehninger, G.; Pimanda, J.; Vadnais, C.; van der Reijden, B.; Hoenes, J.; Lacramioara, B.; Radiovoyevich, T.; Unnikrishnan, A.; Schroeder, T.; Makishima, H.; Platzbecker, U.; Moroy, T.; Jansen, J.; Maciejewski, J.; Helness, A.; Papaemmanuil, E.; Germing, U.; Haas, R.
    72 personalized treatment approach for GFI 136N heterozygous or homozygous MDS patients
    In: Leukemia Research, Jg. 39, 2015, Nr. Suppl. 1, S. S35
    DOI
  • Möröy, Tarik; Vassen, Lothar; Wilkes, Brian; Khandanpour, Cyrus
    From cytopenia to leukemia : the role of Gfi1 and Gfi1b in blood formation
    In: Blood, Jg. 126, 2015, Nr. 24, S. 2561 – 2569
    DOI, Online Volltext (Open Access)
  • Monteferrario, Davide; Bolar, Nikhita A; Marneth, Anna E; Hebeda, Konnie M; Bergevoet, Saskia M; Veenstra, Hans; Laros-van Gorkom, Britta A P; MacKenzie, Marius A; Khandanpour, Cyrus; Botezatu, Lacramiora; Fransen, Erik; Van Camp, Guy; Duijnhouwer, Anthonie L; Salemink, Simone; Willemsen, Brigith; Huls, Gerwin; Preijers, Frank; Van Heerde, Waander; Jansen, Joop H; Kempers, Marlies J E; Loeys, Bart L; Van Laer, Lut; Van der Reijden, Bert A
    A dominant-negative GFI1B mutation in the gray platelet syndrome
    In: The New England Journal of Medicine, Jg. 370, 2014, Nr. 3, S. 245 – 253
    DOI (Open Access)
  • Hones, J.; Botezatu, L.; Thiede, C.; Reijden, B.; Ehninger, G.; Opalka, Bertram; Valk, P.; Lowenberg, B.; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi1 as a novel prognostic marker and tumor suppressor in acute myeloid leukemia
    In: Onkologie, Jg. 36 7, 2013, S. 193 – 193
  • Khandanpour, Cyrus; Möröy, Tarik
    Gfi1 as a regulator of p53 and a therapeutic target for ALL
    In: OncoTarget, Jg. 4, 2013, Nr. 3, S. 374 – 375
    DOI
  • Michel, Lars; Botezatu, L.; Hones, J.; Platzbecker, U.; Schroder, T.; Germing, U.; Rudolph, R.; Sengpiel, Jana; von Verschuer, U.; Grapton, D.; Ehninger, G.; Haas, R.; Moroy, T.; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi136N is a novel prognostic marker for the progression of myelodysplastic syndrome to Acute myeloid leukemia
    In: Onkologie, Jg. 36, 2013, Nr. Suppl. 7, S. 188 – 188
  • Khandanpour, Cyrus; Phelan, James D.; Vassen, Lothar; Schütte, Judith; Chen, Riyan; Horman, Shane R.; Gaudreau, Marie-Claude; Krongold, Joseph; Zhu, Jinfang; Paul, William E.; Dührsen, Ulrich; Göttgens, Bertie; Grimes, H. Leighton; Möröy, Tarik
    Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia
    In: Cancer Cell, Jg. 23, 2013, Nr. 2, S. 200 – 214
    DOI (Open Access)
  • Khandanpour, Cyrus; Dührsen, Ulrich; Röth, Alexander
    Hand-foot syndrome : common presentation in an uncommon situation
    In: European Journal of Haematology, Jg. 91, 2013, Nr. 5, S. 472
    DOI
  • Khandanpour, Cyrus; Dürig, Jan; Dührsen, Ulrich
    Leukämien : Modellkrankheiten für die Entstehung und Behandlung von Krebs
    In: Unikate: Berichte aus Forschung und Lehre, 2013, Nr. 44: Medizin : 50 Jahre Universitätsklinikum Essen, S. 114 – 125
    DOI, Online Volltext (Open Access)
  • Bjerknes, Matthew; Khandanpour, Cyrus; Möröy, Tarik; Fujiyama, Tomoyuki; Hoshino, M.; Klisch, Tiemo J.; Ding, Qian; Gan, Lin; Wang, Jiafang; Martín, Martin G.; Cheng, Hazel
    Origin of the brush cell lineage in the mouse intestinal epithelium
    In: Developmental Biology, Jg. 362, 2012, Nr. 2, S. 194 – 218
    DOI
  • Khandanpour, Cyrus; Krongold, J.; Schütte, Jochen; Bouwman, F.; Vassen, L.; Gaudreau, M. C.; Chen, R.; Calero-Nieto, F. J.; Diamanti, E.; Hannah, R.; Meyer, S. E.; Grimes, H. L.; van der Reijden, B. A.; Jansen, J. H.; Patel, C. V.; Peeters, J. K.; Löwenberg, B.; Dührsen, Ulrich; Göttgens, B.; Möröy, T.
    The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice
    In: Blood, Jg. 120, 2012, Nr. 19, S. 4006 – 4017
    DOI
  • Möröy, Tarik; Khandanpour, Cyrus
    Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation
    In: Seminars in Immunology, Jg. 23, 2011, Nr. 5, S. 368 – 378
    DOI
  • Khandanpour, Cyrus; Kosan, Christian; Gaudreau, Marie-Claude; Dührsen, Ulrich; Hébert, Josée; Zeng, Hui; Möröy, Tarik
    Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease
    In: Stem Cells, Jg. 29, 2011, Nr. 2, S. 376 – 385
    DOI
  • Khandanpour, Cyrus; Thiede, Christian; Valk, Peter J.; Sharif-Askari, Ehssan; Nückel, Holger; Lohmann, Dietmar; Horsthemke, Bernhard; Siffert, Winfried; Neubauer, Andreas; Grzeschik, Karl-Heinz; Bloomfield, Clara D.; Marcucci, Guido; Maharry, Kati; Slovak, Marilyn L.; van der Reijden, Bert A.; Jansen, Joop H.; Schackert, Hans K.; Afshar, Khashayar; Schnittger, Susanne; Peeters, Justine K.; Kroschinsky, Frank; Ehninger, Gerhard; Lowenberg, Bob; Dührsen, Ulrich; Möröy, Tarik
    A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia
    In: Blood, Jg. 115, 2010, Nr. 12, S. 2462 – 2472
    DOI
  • Khandanpour, Cyrus; Möröy, Tarik; Kosan, Christian; Okayama, Taro; Paul, William E.; Sharif-Askari, Ehssan; Vassen, Lothar; Gaudreau, Marie-Claude; Zhu, Jinfang
    Evidence that Growth factor independence 1b (Gfi1b) regulates dormancy and peripheral blood mobilization of hematopoietic stem cells
    In: Blood, Jg. 116, 2010, Nr. 24, S. 5149 – 5161
    DOI
  • Sharif-Askari, Ehssan; Möröy, Tarik; Zeng, Hui; Jin, Jianmin; Okayama, Taro; Heyd, Florian; Gaudreau, Marie-Claude; Khandanpour, Cyrus; Kosan, Christian; Vassen, Lothar
    Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65
    In: Molecular and Cellular Biology (MCB), Jg. 30, 2010, Nr. 16, S. 3929 – 3942
    DOI
  • Vassen, Lothar; Möröy, Tarik; Dührsen, Ulrich; Mahlmann, Stefan; Jansen, Joop H.; van der Reijden, Bert A.; Ebeling, Peter; Khandanpour, Cyrus
    Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia
    In: International Journal of Hematology, Jg. 89, 2009, Nr. 4, S. 422 – 430
    DOI
  • Igwe, Ignatius Emeka; Möröy, Tarik; Brüne, Bernhard; Sharif-Askari, Ehssan; Khandanpour, Cyrus; Kosan, Christian
    The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Iγ2b germline transcripts
    In: European Journal of Immunology, Jg. 38, 2008, Nr. 11, S. 2916 – 3244
    DOI

    • Abstracts

  • Gagelmann, Nico; Stölzel, Friedrich; Fenk, Roland; Holderried, Tobias A.W.; Mueller, Fabian; Tovar, Natalia; Oliver-Caldés, Aina; Rathje, Kristin; Vucinic, Vladan; Kharboutli, Soraya; Bärmann, Ben-Niklas; Ayuk, Francis A.; Platzbecker, Uwe; Albici, Anca Maria; Schub, Natalie; Schmitz, Friederike; Khandanpour, Cyrus; Teichert, Marcel; Jeker, Barbara; Kroeger, Nicolaus; von Tresckow, Bastian; Fernandez de Larrea, Carlos; Pabst, Thomas; Merz, Maximilian
    Cilta-Cel Is Associated with Improved Outcomes and Distinct Cellular Dynamics Compared with Ide-Cel for Relapsed or Refractory Multiple Myeloma
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2025, Nr. Suppl. 1, S. 2004 – 2005
    DOI (Open Access)
  • Berning, Philipp; Maulhardt, Markus; Boyadzhiev, Hristo; Albici, Anca Maria; Janjetovic, Snjezana; Ossami Saidy, Anna; Schultze-Florey, Christian R; Call, Simon; Schub, Natalie; Brioli, Annamaria; Daskalakis, Michael; Knust, Juliane; Hasenkamp, Justin; Stelljes, Matthias; Khandanpour, Cyrus; Bacher, Ulrike; Hanoun, Christine; Heidel, Florian; Reinhardt, Christian; Lenz, Georg; Wulf, Gerald; Stölzel, Friedrich; von Tresckow, Bastian; Pabst, Thomas; Shumilov, Evgenii
    Idecabtagene Vicleucel (ide-cel) Shows Similar Efficacy and Toxicity in Patients with Multiple Myeloma Aged 70 and Older Compared to Younger Patients : A Multicenter Cohort Study
    The 66th ASH Annual Meeting, December 7-10, 2024, San Diego, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2024, Nr. Supplement 1, S. 3383
    DOI (Open Access)
  • Patnana, P. K.; Frank, D.; Vorwerk, J.; Khandanpour, Cyrus; et al.
    Germline variant GFI1-36N affects DNA repair in AML cells resulting in sensitivity to DNA damage and repair therapy
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 135
    DOI (Open Access)
  • Patnana, P. K.; Behrens, M.; Ahmed, H.; Nimmagadda, S. C.; von Bubnoff, N.; Khandanpour, Cyrus
    Growth factor independence 1 expression regulates acute myeloid leukemia cell metabolism by regulating the equilibrium between the rate of glycolysis and oxidative phosphorylation
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 138
    DOI (Open Access)
  • Goldschmidt, Hartmut; Mai, Elias K; Nievergall, Eva; Fenk, Roland; Bertsch, Uta; Tichy, Diana; Besemer, Britta; Dürig, Jan; Schroers, Roland; Metzler, Ivana v.; Haenel, Mathias; Mann, Christoph; Asemissen, Anne-Marie; Heilmeier, Bernhard; Huhn, Stefanie; Kriegsmann, Katharina; Weinhold, Niels; Luntz, Steffen P.; Holderried, Tobias A. W.; Trautmann-Grill, Karolin; Gezer, Deniz; Klaiber-Hakimi, Maika; Mueller, Martin; Khandanpour, Cyrus; Knauf, Wolfgang; Munder, Markus; Geer, Thomas; Riesenberg, Hendrik; Thomalla, Joerg; Hoffmann, Martin; Raab, Marc-Steffen; Salwender, Hans; Weisel, Katja
    Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients : The Phase III GMMG-HD7 Trial
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 138, 2021, Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 463 – 465
    DOI (Open Access)
  • Noman, Helal Mohammed Mohammed Ahmed; Al-Matary, Yahya Saleh; Nimmagadda, Subbaiah Chary; Patnana, Pradeep Kumar; Liu, Longlong; Wei, Lanying; Frank, Daria; Lenz, Georg; Khandanpour, Cyrus
    Leukaemia Cells Induced Metabolic Alterations in AML Associated Mesenchymal Stem Cells Via Notch Signalling
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 138, 2021, Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 4347 – 4348
    DOI (Open Access)
  • Patnana, Pradeep Kumar; Behrens, M.; Klotz, L.; Liebmann, M.; Frank, D.; Nimmagadda, C.; Siveke, Jens; Trajkovic-Arsic, Marija; Hanenberg, Helmut; Thivakaran, Aniththa; Khandanpour, Cyrus
    Growth factor independence 1 expression induced metabolic vulnerabilities and presents novel therapeutic opportunities in acute myeloid leukemia
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 43, 2020, Nr. Suppl. 4, S. 43 – 44
    DOI (Open Access)
  • Heinrichs, D.; Schütte, Jochen; Thivakaran, A.; Al-Matary, Y.; Suslo, M.; Dührsen, U.; Khandanpour, Cyrus
    Curcumin as a treatment approach for MDS/AML in human
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 76
    DOI (Open Access)
  • Fiori, M. N.; Al-Matary, Y.; Fraszczak, J.; Heinrichs, D.; Opalka, Bertram; Dührsen, U.; Möröy, T.; Khandanpour, Cyrus
    The bone marrow niche as a potential target to improve the outcome of acute myeoloid leukemia using dexamethasone
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 73 – 74
    DOI (Open Access)
  • Phelan, James D.; Khandanpour, Cyrus; Horman, Shane; Gaudreau, Marie-Claude; Zhu, Jinfang; Paul, William E.; Dührsen, Ulrich; Grimes, H. Leighton; Moroy, Tarik
    Growth Factor Independent-1 (Gfi1) Is Critically Required for T-Cell Acute Lymphoblastic Leukemia (T-ALL) Tumor Initiation and Maintenance
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 116, 2010, Nr. 21, S. 1299
    DOI

    • Bücher/Sammelwerke/Tagungsbände

  • Khandanpour, Cyrus
    Funktion der Transkriptonsfaktoren Gfi1 und Gfi1b in der physiologischen und malignen Entwicklung des hämatopoetischen Systems
    Duisburg ; Essen, 2017

    • Dissertation

  • Khandanpour, Cyrus
    Affinitätschromatographie mit orientiert und nicht-orientiert immobilisiertem Calmodulin am Beispiel der Aufreinigung der Ubiquityl-Calmodulin-Synthetase Faktor 2
    Duisburg-Essen, 2005
    Online Volltext, Online Volltext

    • Poster / Posterbeiträge

  • Maulhardt, Markus; Berning, Philipp; Hanoun, Christine; Boyadzhiev, Hristo; Albici, Anca Maria; Janjetovic, Snjezana; Ossami Saidy, Anna; Call, Simon; Schub, Natalie; Aydilek, Enver; Daskalakis, Michael; Jung, Wolfram; Hasenkamp, Justin; Krekeler, Carolin; Khandanpour, Cyrus; Bacher, Ulrike; Reinhardt, Hans Christian; Lenz, Georg; Stölzel, Friedrich; Wulf, Gerald; Pabst, Thomas; von Tresckow, Bastian; Shumilov, Evgenii
    Efficacy of Idecabtagene Vicleucel (ide-cel) in Patients with Relapsed/Refractory Multiple Myeloma and Prior Central Nervous System Manifestation: A Retrospective Real-World Analysis
    66th ASH Annual Meeting, December 7-10, 2024, San Diego, CA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2024, Nr. Supplement 1, S. 4759 – 4760
    DOI (Open Access)
  • Eisfeld, C.; Kajüter, H.; Möller, L.; Oesterling, F.; Khandanpour, Cyrus; Stang, Andreas
    Entwicklungen im Überleben beim Multiplen Myelom : eine Analyse des Krebsregisters NRW
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 85 – 86
    DOI (Open Access)