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Universitätsprofessor/in, Institut für Anatomie
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SoSe 2024
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WiSe 2020
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Overexpression of Human sFLT1 in the Spongiotrophoblast Is Sufficient to Induce Placental Dysfunction and Fetal Growth Restriction in Transgenic MiceIn: International Journal of Molecular Sciences (IJMS), Jg. 25, 2024, Nr. 4, 2040DOI, Online Volltext (Open Access)
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Abnormal expression of the costimulatory molecule B7‐H4 in placental chorionic villous and decidual basalis tissues of patients with preeclampsia and HELLP syndromeIn: American Journal of Reproductive Immunology, Jg. 86, 2021, Nr. 3, e13430DOI (Open Access)
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Circulating Maternal sFLT1 (Soluble fms-Like Tyrosine Kinase-1) Is Sufficient to Impair Spiral Arterial Remodeling in a Preeclampsia Mouse ModelIn: Hypertension, Jg. 78, 2021, Nr. 4, S. 1067 – 1079DOI (Open Access)
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Superiority of focused ion beam-scanning electron microscope tomography of cardiomyocytes over standard 2D analyses highlighted by unmasking mitochondrial heterogeneityIn: Journal of Cachexia, Sarcopenia and Muscle, Jg. 12, 2021, Nr. 4, S. 933 – 954DOI, Online Volltext (Open Access)
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CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive PlacentaIn: Frontiers in Endocrinology, Jg. 11, 2020, 597549DOI, Online Volltext (Open Access)
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Human sFLT1 leads to severe changes in placental differentiation and vascularization in a transgenic hsFLT1/rtTA FGR mouse modelIn: Frontiers in Endocrinology, Jg. 10, 2019, 165DOI, Online Volltext (Open Access)
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CSDC2, a cold shock domain RNA-binding protein in decidualizationIn: Journal of Cellular Physiology, Jg. 234, 2018, Nr. 1, S. 740 – 748DOI (Open Access)
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Mouse cardiac mitochondria do not separate in subsarcolemmal and interfibrillar subpopulationsIn: Mitochondrion, Jg. 38, 2018, S. 1 – 5
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Protection of oligodendrocytes through neuronal overexpression of the small GTPase ras in hyperoxia-induced neonatal brain injuryIn: Frontiers in Neurology, Jg. 9, 2018, S. 175DOI, Online Volltext (Open Access)
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Placental-Specific Overexpression of sFlt-1 Alters Trophoblast Differentiation and Nutrient Transporter Expression in an IUGR Mouse ModelIn: Journal of Cellular Biochemistry, Jg. 118, 2017, Nr. 6, S. 1316 – 1329
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Transplacental Nutrient Transport Mechanisms of Intrauterine Growth Restriction in Rodent Models and HumansIn: Frontiers in Physiology, Jg. 8, 2017, S. 951DOI (Open Access)
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CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration propertiesIn: Cell Adhesion & Migration, Jg. 10, 2016, Nr. 1-2, S. 163 – 178DOI, Online Volltext (Open Access)
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CCN3 signaling is dysregulated in the pregnancy disorder preeclampsiaIn: Journal of Reproductive Immunology, Jg. 115, 2016, S. 71 – 71
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CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxinIn: European Journal of Immunology, Jg. 46, 2016, Nr. 8, S. 2028 – 2042DOI (Open Access)
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Direct conversion of fibroblasts traces the way back to our first organ-the placentaIn: Stem Cell Investigation, 2016DOI (Open Access)
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Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrestIn: Development / Company of Biologists, Jg. 143, 2016, Nr. 5, S. 787 – 798DOI (Open Access)
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A suppressive antagonism evidences progesterone and estrogen receptor pathway interaction with concomitant regulation of Hand2, Bmp2 and ERK during early decidualizationIn: PLoS ONE, Jg. 10, 2015, Nr. 4, S. e0124756DOI (Open Access)
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Altered epidermal lipid processing and calcium distribution in the KID syndrome mouse model Cx26S17FIn: FEBS Letters, Jg. 589, 2015, Nr. 15, S. 1904 – 1910DOI (Open Access)
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Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in miceIn: Journal of Lipid Research, Jg. 56, 2015, Nr. 4, S. 821 – 835DOI (Open Access)
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Gap junction connexins in female reproductive organs : Implications for women's reproductive healthIn: Human Reproduction Update, Jg. 21, 2015, Nr. 3, S. 340 – 352
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Oxygen Sensitivity of Placental Trophoblast Connexins 43 and 46 : A Role in Preeclampsia?In: Journal of Cellular Biochemistry, Jg. 116, 2015, Nr. 12, S. 2924 – 2937
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Physiological roles of connexins in labour and lactationIn: Reproduction, Jg. 150, 2015, Nr. 4, S. R129 – R136
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Reduced gene dosage of Tfap2c impairs trophoblast lineage differentiation and alters maternal blood spaces in the mouse placentaIn: Biology of Reproduction, Jg. 93, 2015, Nr. 2, S. 31DOI (Open Access)
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Blastocyst implantation failure relates to impaired translational machinery gene expressionIn: Reproduction, Jg. 148, 2014, Nr. 1, S. 87 – 98DOI (Open Access)
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CCN3 (NOV) : A key player in trophoblast differentiation promoting cell cycle exit and migration of extravillous trophoblast cells and its role in preeclampsiaIn: Placenta, Jg. 35, 2014, Nr. 9, S. A108
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Connexin31.1 (Gjb5) deficiency blocks trophoblast stem cell differentiation and delays placental developmentIn: Stem Cells and Development, Jg. 23, 2014, Nr. 21, S. 2649 – 2660DOI, Online Volltext (Open Access)
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Impact of repetitive exposure to strong static magnetic fields on pregnancy and embryonic development of miceIn: Journal of Magnetic Resonance Imaging, Jg. 39, 2014, Nr. 3, S. 691 – 699
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Repetitive exposure of mice to strong static magnetic fields in utero does not impair fertility in adulthood but may affect placental weight of offspringIn: Journal of Magnetic Resonance Imaging, Jg. 39, 2014, Nr. 3, S. 683 – 690
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The role of the CCN family of proteins in female reproductionIn: Cellular and Molecular Life Sciences - CMLS, Jg. 71, 2014, Nr. 12, S. 2299 – 2311
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CCN3 regulates proliferation and migration properties in Jeg3 trophoblast cells via ERK1/2, akt and notch signallingIn: Molecular Human Reproduction: MHR, Jg. 19, 2013, Nr. 4, S. 237 – 249
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Decidual angiogenesis and placental orientation are altered in mice heterozygous for a dominant loss-of-function Gja1 (Connexin43) mutationIn: Biology of Reproduction, Jg. 89, 2013, Nr. 5, S. 1 – 12
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The Gap Junction Channel encoding Genes Connexin31 (Gjb3) and Connexin31.1 (Gjb5) have Directly Opposed Effects on Trophoblast Stem Cell Differentiation during Mouse Placental DevelopmentIn: Placenta, Jg. 34, 2013, S. A50 – A51
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Connexin 31 (GJB3) deficiency in mouse trophoblast stem cells alters giant cell differentiation and leads to loss of oxygen sensingIn: Biology of Reproduction, Jg. 87, 2012, Nr. 2, S. 37
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Repetitive exposure to a 7 Tesla static magnetic field of mice in utero does not cause alterations in basal emotional and cognitive behavior in adulthoodIn: Reproductive Toxicology, Jg. 34, 2012, Nr. 1, S. 86 – 92
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TCFAP2C dependent trophoblast lineage differentiation during placental developmentIn: Placenta, Jg. 33, 2012, Nr. 9, S. A68 – A68
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The CCN3 protein regulates proliferation and migration properties in JEG3 throphoblast cells via ERK1/2 art and notch signallingIn: Placenta, Jg. 33, 2012, Nr. 9, S. A70 – A70
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The molecular role of connexin 43 in human trophoblast cell fusionIn: Biology of Reproduction, Jg. 86, 2012, Nr. 4, S. 115
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Uterine NK Cells Are Critical in Shaping DC Immunogenic Functions Compatible with Pregnancy ProgressionIn: PLoS ONE, Jg. 7, 2012, Nr. 10, e46755DOI (Open Access)
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Blastocyst-mediated induction of endometrial connexins : an inflammatory response?In: Journal of Reproductive Immunology, Jg. 90, 2011, Nr. 1, S. 9 – 13
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Hormone-induced delayed ovulation affects early embryonic developmentIn: Fertility and Sterility, Jg. 95, 2011, Nr. 7, S. 2390 – 2394
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Impact of CCN3 (NOV) glycosylation on migration/invasion properties and cell growth of the choriocarcinoma cell line Jeg3In: Human Reproduction, Jg. 26, 2011, Nr. 10, S. 2850 – 2860
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Ovarian steroid receptors and activated MAPK in the regional decidualization in Rats1In: Biology of Reproduction, Jg. 84, 2011, Nr. 5, S. 1063 – 1071DOI (Open Access)
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Peripheral lymphangiogenesis in mice depends on ectodermal connexin-26 (Gjb2)In: Journal of Cell Science, Jg. 124, 2011, Nr. 16, S. 2806 – 2815DOI (Open Access)
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Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thicknessIn: Nature Nanotechnology, Jg. 6, 2011, Nr. 12, S. 824 – 833
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The oxygen-sensitive CCN3 protein regulates both, trophoblast migration/invasion and proliferationIn: Placenta, Jg. 32, 2011, Nr. 9, S. A61 – A61
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HIF-1beta determines ABCA1 expression under hypoxia in human macrophagesIn: The International Journal of Biochemistry & Cell Biology, Jg. 42, 2010, Nr. 2, S. 241 – 252
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More insights into the CCN3/connexin43 interaction complex and its role for signalingIn: Journal of Cellular Biochemistry, Jg. 110, 2010, Nr. 1, S. 129 – 140
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Regulation of the Matricellular Proteins CYR61 (CCN1) and NOV (CCN3) by Hypoxia-Inducible Factor-1α and Transforming-Growth Factor-β3 in the Human TrophoblastIn: Endocrinology, Jg. 151, 2010, Nr. 6, S. 2835 – 2845
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Screening for embryonic loss during in utero development of mice with a human 1.5 Tesla clinical MRI scannerIn: Journal of Magnetic Resonance Imaging, Jg. 32, 2010, Nr. 5, S. 1158 – 1165
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The Transcription Factor TCFAP2C/AP-2 Cooperates with CDX2 To Maintain Trophectoderm FormationIn: Molecular and Cellular Biology (MCB), Jg. 30, 2010, Nr. 13, S. 3310 – 3320
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The liver X receptor (LXR) and its target gene ABCA1 are regulated upon low oxygen in human trophoblast cells : A reason for alterations in preeclampsia?In: Placenta, Jg. 31, 2010, Nr. 10, S. 910 – 918
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Progestins inhibit expression of MMPs and of angiogenic factors in human ectopic endometrial lesions in a mouse modelIn: Molecular Human Reproduction: MHR, Jg. 15, 2009, Nr. 10, S. 633 – 643DOI (Open Access)
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Novel germ cell markers characterize testicular seminoma and fetal testisIn: Molecular Human Reproduction: MHR, Jg. 13, 2007, Nr. 10, S. 721 – 727
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Cell line specific modulation of connexin43 expression after exposure to ionizing radiationIn: Cell Communication and Adhesion, Jg. 12, 2005, Nr. 5-6, S. 249 – 259
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Gene signatures of testicular seminoma with emphasis on expression of ets variant gene 4In: Cellular and Molecular Life Sciences - CMLS, Jg. 62, 2005, Nr. 19-20, S. 2359 – 2368
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Östrogene - Wirkung und Risiko : Botenstoffe des Körpers und TherapeutikumIn: Essener Unikate: Berichte aus Forschung und Lehre, 2005, Nr. 25 : Medizin – Unsere Hormone, S. 38 – 45Online Volltext, Online Volltext (Open Access)
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Rabbit endometrium in organ culture : Morphological evidence for progestational differentiation in vitroIn: Cell and Tissue Research, Jg. 257, 1989, Nr. 3, S. 505 – 518
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Gap junction formation in rabbit uterine epithelium in response to embryo recognitionIn: Developmental Biology, Jg. 126, 1988, Nr. 1, S. 203 – 211
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Lipiddomänen der Plasmamembran im Uterusepithel von Kaninchen zum Zeitpunkt der Implantation : Eine gefrierbruch-zytochemische UntersuchungIn: Acta histochemica. Supplementband, Jg. 36, 1988, S. 395 – 398
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Apical plasma membrane-bound enzymes of rabbit uterine epithelium : Pattern changes during the periimplantation phaseIn: Histochemistry, Jg. 87, 1987, Nr. 6, S. 517 – 529
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Dreidimensionale Aggregate von Chorionkarzinomzellen als ein In-vitro-Modell für den invasiven TrophoblastenIn: Verhandlungen der Anatomischen Gesellschaft (Ergänzungsheft zu Anatomischer Anzeiger), Jg. 81 =162 Erg.-Heft, 1987, S. 499 – 500
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Immunhistochemischer Nachweis des 26k-Proteins der gap junctions im Uterusepithel des Kaninchens in Abhängigkeit von der ReproduktionsphaseIn: Verhandlungen der Anatomischen Gesellschaft (Ergänzungsheft zu Anatomischer Anzeiger), Jg. 81 =162 Erg.-Heft, 1987, S. 503 – 504
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Editorial: Causes and Consequences of Intrauterine Growth RestrictionIn: Frontiers in Endocrinology. Lausanne: Frontiers Media SA, Jg. 11, 2020, 205DOI (Open Access)
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Matricellular CCN1 and CCN3 proteins are key regulators at the fetal-maternal interface by promoting cell cycle exit and migration of extravillous trophoblast cellsIn: Placenta. Amsterdam: Elsevier, Jg. 34, 2013, S. A87
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Regulation of placental connexins 43 and 46 upon low oxygen and its impact on preeclampsia
International Federation of Placenta Associations Meeting 2012, 18 - 21 September 2012, Hiroshima, Japan,In: Placenta. Amsterdam: Elsevier, Jg. 33, 2012, Nr. 9, S. A86 – A86 -
The CCN3 protein : Regulator of trophoblast proliferation and migration/invasion, and its contribution to preeclampsiaIn: Journal of Reproductive Immunology. Amsterdam: Elsevier, Jg. 94, 2012, Nr. 1, S. 71
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The effect of oxygen on placental connexins 43 and 46 and its contribution to preeclampsia
joint International Congress of the American Society for Reproductive Immunology (ASRI) & the European Society for Reproductive Immunology (ESRI), May 31 - June 2, 2012, Hamburg, Germany,In: Journal of Reproductive Immunology. Amsterdam: Elsevier, Jg. 94, 2012, Nr. 1, S. 34 – 35 -
The role of CCN3 (NOV) on migratory and invasive properties of trophoblast cellsIn: European Journal of Cell Biology (EJCB). Amsterdam: Elsevier, Jg. 89, 2010, Nr. Suppl. 60, S. 11 – 11
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Role of Steroid Hormones : Estrogen and EndometriosisIn: Endometriosis: science and practice / Giudice, Linda C.; Evers, Johannes Leonardus Henricus; Healy, David L. (Hrsg.). Oxford: Wiley-Blackwell, 2012, S. 140 – 144
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Changes in Lipid Organization of Uterine Epithelial Cell Membranes at Implantation in the RabbitIn: Trophoblast Invasion and Endometrial Receptivity: Novel Aspects of the Cell Biology of Embryo Implantation / Denker, Hans-Werner; Aplin, John D. (Hrsg.). Boston: Springer, 1990, S. 323 – 338
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Penetration of the basal lamina by processes of uterine epithelial cells during implantation in the rabbitIn: Trophoblast Invasion and Endometrial Receptivity: Novel Aspects of the Cell Biology of Embryo Implantation / Denker, Hans-Werner; Aplin, John D. (Hrsg.). Boston: Springer, 1990, S. 417 – 430
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The effect of oxygen on placental connexins 43 and 46 and its contribution to preeclampsia
International Federation of Placenta Associations Meeting 2011, 14 - 17 September 2011, Geilo, Norway,In: Placenta. Amsterdam: Elsevier, Jg. 32, 2011, Nr. 9, S. A86 -
Bestimmt die Plazenta unsere Gesundheit im späteren Leben?
Die kleine Form, 02. November 2011, Essen,2011(Die kleine Form 2011/2012)