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Institut für Virologie der Medizinischen Fakultät

Anschrift
Virchowstr. 179 / Robert-Koch-Haus
45147 Essen

Funktionen

  • Universitätsprofessor/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Yang, Li; Gong, Ying; Liu, Feifei; Chen, Wuhong; Wang, Xinran; Long, Guozhang; Li, Heng; Xiao, Fuling; Lu, Mengji; Hu, Youhong; Tong, Xiankun; Zuo, Jianping
    A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression
    In: Antiviral Research Jg. 221 (2024) 105763
  • Liang, Yaojie; Luo, Xufeng; Schefczyk, Stefan; Muungani, Lorraine T.; Deng, Hui; Wang, Baoju; Baba, Hideo Andreas; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut; Bröring, Ruth
    Hepatitis B surface antigen expression impairs endoplasmic reticulum stress-related autophagic flux by decreasing LAMP2
    In: JHEP Reports Jg. 6 (2024) Nr. 4, 101012
  • Li, Jia; Lin, Yong; Wang, Xueyu; Lu, Mengji
    Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release
    In: Virologica Sinica Jg. 39 (2024) Nr. 1, S. 24 - 30
  • Xu, Shilei; Deng, Ke-Qiong; Lu, Chengbo; Fu, Xin; Zhu, Qingmei; Wan, Shiqi; Zhang, Lin; Huang, Yu; Nie, Longyu; Cai, Huanhuan; Wang, Qiming; Zeng, Hao; Zhang, Yufeng; Wang, Fubing; Ren, Hong; Chen, Yu; Yan, Huan; Xu, Ke; Zhou, Li; Lu, Mengji; Zhu, Ying; Liu, Shi; Lu, Zhibing
    Interleukin-6 classic and trans-signaling utilize glucose metabolism reprogramming to achieve anti- or pro-inflammatory effects
    In: Metabolism Jg. 155 (2024) 155832
  • Wang, Qin; Liu, Yanan; Luo, Jinzhuo; Yang, Shangqing; Wang, Lu; Lu, Yinping; Feng, Xuemei; Yang, Xuecheng; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Zheng, Xin; Yang, Dongliang; Liu, Jia
    A systematic comparison reveals dynamic differences in early adaptive immune responses of acute-resolving versus chronic HBV replication
    In: Journal of Medical Virology Jg. 95 (2023) Nr. 3, e28670
  • Yang, Lu; Zhou, Di; Martin, Kächele; Wu, Jun; Chen, Mingfa; Lu, Mengji; Yang, Dongliang; Protzer, Ulrike; Roggendorf, Michael; Song, Jingjiao
    Aborted infection of human sodium taurocholate cotransporting polypeptide (hNTCP) expressing woodchuck hepatocytes with hepatitis B virus (HBV)
    In: Virus Genes Jg. 59 (2023) S. 823 - 830
  • Zhao, Zhenyu; Wei, Zhen; Zheng, Jiaxin; Li, Zhihong; Zou, Hecun; Wen, Xiang; Li, Fahong; Wang, Xueyu; Huang, Qian; Zeng, Huaqing; Fan, Hui; Cai, Xuefei; Zhang, Jiming; Jia, Bei; Huang, Ailong; Lu, Mengji; Lin, Yong
    Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways
    In: Emerging Microbes & Infections Jg. 12 (2023) Nr. 2, 2261556
  • Yu, Jie; Shen, Zhongliang; Chen, Shiqi; Liu, Hongyan; Du, Zunguo; Mao, Richeng; Wang, Jinyu; Zhang, Yongmei; Zhu, Haoxiang; Yang, Sisi; Li, Jing; Wu, Jingwen; Dong, Minhui; Zhu, Mengqi; Huang, Yuxian; Li, Jianhua; Yuan, Zhenghong; Xie, Youhua; Lu, Mengji; Zhang, Jiming
    Inhibition of HBV replication by EVA1A via enhancing cellular degradation of HBV components and its potential therapeutic application
    In: Antiviral Research Jg. 216 (2023) 105643
  • Zheng, Jiaxin; Deng, Yingying; Wei, Zhen; Zou, Hecun; Wen, Xiang; Cai, Jia; Zhang, Shujun; Jia, Bei; Lu, Mengji; Lu, Kefeng; Lin, Yong
    Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions
    In: Antiviral Research Jg. 213 (2023) 105601
  • He, Qiao-qiao; Huang, Yu; Nie, Longyu; Ren, Sheng; Xu, Gang; Deng, Feiyan; Cheng, Zhikui; Zuo, Qi; Zhang, Lin; Cai, Huanhuan; Wang, Qiming; Wang, Fubing; Ren, Hong; Yan, Huan; Xu, Ke; Zhou, Li; Lu, Mengji; Lu, Zhibing; Zhu, Ying; Liu, Shi
    MAVS integrates glucose metabolism and RIG-I-like receptor signaling
    In: Nature Communications Jg. 14 (2023) Nr. 1, 5343
  • Westmeier, Jaana; Brochtrup, Annika; Paniskaki, Krystallenia; Karakoese, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Limmer, Andreas; Mittermüller, Daniela; Liu, Jia; Zheng, Xin; Koval, Tetiana; Kaidashev, Igor; Berger, Marc Moritz; Herbstreit, Frank; Brenner, Thorsten; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients
    In: Frontiers in Immunology Jg. 14 (2023) 1236374
  • Wang, Jinyu; Zhang, Xueyun; Han, Jiajia; Zhou, Pu; Yu, Xueping; Shen, Zhongliang; Mao, Richeng; Lu, Mengji; Huang, Yuxian; Zhang, Jiming
    MicroRNA-124 expression in Kupffer cells modulates liver injury by targeting IL-6/STAT3 signaling
    In: Antiviral Research Jg. 211 (2023) 105510
  • Xie, Zhanglian; Shen, Sheng; Huang, Kuiyuan; Wang, Weibin; Liu, Ziying; Zhang, Haixing; Lu, Mengji; Sun, Jian; Hou, Jinlin; Liu, Hongyan; Guo, Haitao; Zhang, Xiaoyong
    Mitochondrial HIGD1A inhibits hepatitis B virus transcription and replication through the cellular PNKD-NF-κB-NR2F1 nexus
    In: Journal of Medical Virology Jg. 95 (2023) Nr. 4, e28749
  • Luo, Xufeng; Zhang, Rui; Schefczyk, Stefan; Liang, Yaojie; Lin, Shu S.; Liu, Shi; Baba, Hideo Andreas; Lange, Christian M.; Wedemeyer, Heiner; Lu, Mengji; Bröring, Ruth
    Nuclear translocation of YAP drives BMI1-associated hepatocarcinogenesis in hepatitis B virus infection
    In: Liver International Jg. 43 (2023) Nr. 9, S. 2002 - 2016
  • Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Trippler, Martin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut; Bröring, Ruth
    Poly(I:C) Induces Distinct Liver Cell Type-Specific Responses in Hepatitis B Virus-Transgenic Mice In Vitro, but Fails to Induce These Signals In Vivo
    In: Viruses Jg. 15 (2023) Nr. 5, 1203
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Liu, Jing; Deng, Hui; Yang, Xuecheng; Wang, Hua; Feng, Xuemei; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Wang, Baoju; Yang, Dongliang; Zheng, Xin; Liu, Jia
    SARS-CoV-2-specific T cell responses wane profoundly in convalescent individuals 10 months after primary infection
    In: Virologica Sinica (2023) in press
  • Karakoese, Zehra; Le-Trilling, Vu Thuy Khanh; Schuhenn, Jonas; Francois, Sandra; Lu, Mengji; Liu, Jia; Trilling, Mirko; Hoffmann, Daniel; Dittmer, Ulf; Sutter, Kathrin
    Targeted mutations in IFNα2 improve its antiviral activity against various viruses
    In: mBio Jg. 14 (2023) Nr. 6, e02357-23
  • Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Hasenberg, Mike; Walkenfort, Bernd; Trippler, Martin; Schuhenn, Jonas; Sutter, Kathrin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut H.; Broering, Ruth
    Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitis
    In: Scientific Reports Jg. 13 (2023) Nr. 1, 22829
  • Zhang, Yue; Yan, Hu; Li, Xian; Zhou, Dihan; Zhong, Maohua; Yang, Jingyi; Zhao, Bali; Fan, Xuxu; Fan, Jun; Shu, Jiayi; Lu, Mengji; Jin, Xia; Zhang, Ejuan; Yan, Huimin
    A high-dose inoculum size results in persistent viral infection and arthritis in mice infected with chikungunya virus
    In: PLoS Neglected Tropical Diseases Jg. 16 (2022) Nr. 1, e0010149
  • Wang, Xueyu; Wei, Zhiqiang; Lan, Tingyu; He, Yulin; Cheng, Bin; Li, Ruimin; Chen, Hongxia; Li, Fahong; Liu, Guohua; Jiang, Bin; Lin, Yong; Lu, Mengji; Meng, Zhongji
    CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation
    In: Autophagy Jg. 18 (2022) Nr. 2, S. 357 - 374
  • Zheng, Jiaxin; Deng, Yingying; Zhao, Zhenyu; Mao, Binli; Lu, Mengji; Lin, Yong; Huang, Ailong
    Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects
    In: Cellular & Molecular Immunology Jg. 19 (2022) Nr. 2, S. 150 - 157
  • Zhang, Ejuan; Ma, Zhiyong; Lu, Mengji
    Contribution of T- and B-cell intrinsic toll-like receptors to the adaptive immune response in viral infectious diseases
    In: Cellular and Molecular Life Sciences - CMLS Jg. 79 (2022) Nr. 11, 547
  • Wang, Xueyu; Wei, Zhiqiang; Cheng, Bin; Li, Jia; He, Yulin; Lan, Tingyu; Kemper, Thekla; Lin, Yong; Jiang, Bin; Jiang, Yongfang; Meng, Zhongji; Lu, Mengji
    Endoplasmic reticulum stress promotes HBV production by enhancing use of the autophagosome/multivesicular body axis
    In: Hepatology Jg. 75 (2022) Nr. 2, S. 438 - 454
  • Liu, Shuhui; Zhao, Kaitao; Su, Xi; Gao, Xiaoxiao; Yao, Yongxuan; Kong, Ranran; Wang, Yun; Wu, Chunchen; Lu, Mengji; Chen, Xinwen; Pei, Rongjuan
    Enhanced host immune responses in presence of HCV facilitate HBV clearance in coinfection
    In: Virologica Sinica Jg. 37 (2022) Nr. 3, S. 408 - 417
  • Xia, Jianbo; Cao, Liang; Zhao, Zhenyu; Deng, Yingying; Lu, Mengji; Wu, Chunchen; Lin, Yong
    HBV sL13H mutation impairs its surface antigen expression and ability to induce autophagy
    In: Genes & Diseases Jg. 9 (2022) Nr. 6, S. 1401 - 1404
  • Xie, Xiaohong; Luo, Jinzhuo; Zhu, Dan; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Mengji; Zheng, Xin; Dittmer, Ulf; Yang, Dongliang; Liu, Jia
    HBeAg Is Indispensable for Inducing Liver Sinusoidal Endothelial Cell Activation by Hepatitis B Virus
    In: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022) 797915
  • Li, Fahong; Deng, Yingying; Zhang, Shenyan; Zhu, Beidi; Wang, Jun; Wang, Jinyu; Wang, Xueyu; Zhao, Zhenyu; Deng, Wanyu; Mao, Richeng; Shen, Zhongliang; Chen, Jieliang; Bröring, Ruth; Lin, Yong; Lu, Mengji; Zhang, Jiming
    Human hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines
    In: Emerging Microbes & Infections Jg. 11 (2022) Nr. 1, S. 616 - 628
  • Podschwadt, Philip; Malyshkina, Anna; Windmann, Sonja; Papadamakis, Athanasios; Kerkmann, Leonie; Lapuente, Dennis; Tenbusch, Matthias; Lu, Mengji; Schindler, Michael; Lang, Karl Sebastian; Hansen, Wiebke; Bayer, Wibke
    Immune suppression of vaccine-induced CD8⁺ T cell-responses by gamma retrovirus envelope is mediated by interleukin-10 producing CD4⁺ T cells
    In: Frontiers in Immunology Jg. 13 (2022) 934399
  • Li, Jia; Kemper, Thekla; Bröring, Ruth; Chen, Jieliang; Yuan, Zhenghong; Wang, Xueyu; Lu, Mengji
    Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication
    In: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022) 804011
  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Wang, Kai; Mennerich, Denise; Hu, Jie; Zhao, Zhenyu; Zheng, Jiaxin; Deng, Yingying; Katschinski, Benjamin; Xu, Shilei; Zhang, Guiji; Cai, Xuefei; Hu, Yuan; Wang, Jianwei; Lu, Mengji; Huang, Ailong; Tang, Ni; Trilling, Mirko; Lin, Yong
    Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro
    In: Emerging Microbes & Infections Jg. 11 (2022) Nr. 1, S. 483 - 497
  • Du, Yanqin; Wu, Jun; Liu, Jia; Zheng, Xin; Yang, Dongliang; Lu, Mengji
    Toll-like receptor-mediated innate immunity orchestrates adaptive immune responses in HBV infection
    In: Frontiers in Immunology Jg. 13 (2022) 965018
  • Liu, Jia; Yang, Xuecheng; Wang, Hua; Li, Ziwei; Deng, Hui; Liu, Jing; Xiong, Shue; He, Junyi; Feng, Xuemei; Guo, Chunxia; Wang, Weixian; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Senff, Tina; Menne, Christopher; Timm, Jörg; Zhang, Yanfang; Deng, Fei; Lu, Yinping; Wu, Jun; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Wang, Baoju; Zheng, Xin
    Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairment
    In: mBio Jg. 12 (2021) Nr. 2, S. e00085 - 21
  • Li, Qian; Wang, Jun; Zhou, Xueshi; Lu, Hongzhou; Lu, Mengji; Huang, Lihua
    Case Report: Viral Pneumonia Could Prompt the Advancement of Immune-Mediated Liver Disease
    In: Frontiers in Medicine Jg. 8 (2021) 582620
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Deng, Hui; Wang, Hua; Feng, Xuemei; Quan, Xufeng; Wang, Xiaoyan; Li, Sumeng; Lu, Sihong; Yang, Xuecheng; Wang, Baoju; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Zheng, Xin; Liu, Jia
    Characterization of SARS-CoV-2-Specific Humoral and Cellular Immune Responses Induced by Inactivated COVID-19 Vaccines in a Real-World Setting
    In: Frontiers in Immunology Jg. 12 (2021) 802858
  • Bröring, Ruth; Luo, Xufeng; Liu, Jia; Lu, Mengji
    Controversial: Early Innate Responses to Hepatitis B Virus Infection, an Explanation for Viral Persistence?
    In: Virologica Sinica Jg. 36 (2021) Nr. 1, S. 163 - 166
  • Xiang, Tiandan; Liang, Boyun; Fang, Yaohui; Lu, Sihong; Li, Sumeng; Wang, Hua; Li, Huadong; Yang, Xiaoli; Shen, Shu; Zhu, Bin; Wang, Baoju; Wu, Jun; Liu, Jia; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Trilling, Mirko; Deng, Fei; Zheng, Xin
    Declining Levels of Neutralizing Antibodies Against SARS-CoV-2 in Convalescent COVID-19 Patients One Year Post Symptom Onset
    In: Frontiers in Immunology Jg. 12 (2021) 708523
  • Du, Yanqin; Yang, Xiaoli; Li, Jia; Sokolova, Viktoriya; Zou, Shi; Han, Meihong; Yan, Hu; Wey, Karolin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Epple, Matthias; Wu, Jun
    Delivery of toll-like receptor 3 ligand poly(I:C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect in a mouse model
    In: Acta Biomaterialia Jg. 133 (2021) S. 297 - 307
  • Chen, Jieliang; Li, Yaming; Lai, Fritz; Wang, Yang; Sutter, Kathrin; Dittmer, Ulf; Ye, Jianyu; Zai, Wenjing; Liu, Min; Shen, Fang; Wu, Min; Hu, Kongying; Li, Baocun; Lu, Mengji; Zhang, Xiaonan; Zhang, Jiming; Li, Jianhua; Chen, Qingfeng; Yuan, Zhenghong
    Functional Comparison of Interferon-α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-α and Interferon-γ Signaling
    In: Hepatology Jg. 73 (2021) Nr. 2, S. 486 - 502
  • Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Buitrago-Molina, Laura Elisa; Lu, Mengji; Meyer, Hemmo; Tong, Chun-Kit
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
    In: Autophagy Jg. 17 (2021) Nr. 1, S. 1 - 382
  • Xie, Xiaohong; Luo, Jinzhuo; Bröring, Ruth; Zhu, Dan; Zhou, Wenqing; Lu, Mengji; Zheng, Xin; Dittmer, Ulf; Yang, Dongliang; Liu, Jia
    HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance
    In: Cellular & Molecular Immunology Jg. 18 (2021) Nr. 11, S. 2572 - 2574
  • Li, Qian; Wang, Jun; Islam, Heba; Kirschning, Carsten Jürgen; Lu, Hongzhou; Hoffmann, Daniel; Dittmer, Ulf; Lu, Mengji
    Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis
    In: Cell Death and Disease Jg. 12 (2021) Nr. 1, 34
  • Zhou, Li; He, Rui; Fang, Peining; Li, Mengqi; Yu, Haisheng; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Lin, Yong; Zhang, Rui; Trilling, Mirko; Bröring, Ruth; Lu, Mengji; Zhu, Ying; Liu, Shi
    Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 98
  • Luo, Xufeng; Zhang, Rui; Lu, Mengji; Liu, Shi; Baba, Hideo Andrea; Gerken, Guido; Wedemeyer, Heiner; Bröring, Ruth
    Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 12 (2021) 684424
  • Du, Yanqin; Bröring, Ruth; Li, Xiaoran; Zhang, Xiaoyong; Liu, Jia; Yang, Dongliang; Lu, Mengji
    In Vivo Mouse Models for Hepatitis B Virus Infection and Their Application
    In: Frontiers in Immunology Jg. 12 (2021) 766534
  • Xiong, Shue; Zhu, Dan; Liang, Boyun; Li, Mingyue; Pan, Wen; He, Junyi; Wang, Hua; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Liu, Di; Yang, Dongliang; Liu, Jia; Zheng, Xin
    Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg loss
    In: EBioMedicine Jg. 69 (2021) 103464
  • Du, Yanqin; Yan, Hu; Zou, Shi; Khera, Tanvi; Li, Jia; Han, Meihong; Yang, Xiaoli; Wang, Baoju; Liu, Jia; Sun, Shuilin; Zheng, Xin; Dittmer, Ulf; Lu, Mengji; Yang, Dongliang; Wedemeyer, Heiner; Wu, Jun
    Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model
    In: Hepatology Communications Jg. 5 (2021) Nr. 5, S. 865 - 881
  • Wu, Jun; Liang, Bo-Yun; Fang, Yao-Hui; Wang, Hua; Yang, Xiao-Li; Shen, Shu; Chen, Liang-Kai; Li, Su-Meng; Lu, Si-Hong; Xiang, Tian-Dan; Liu, Jia; Le-Trilling, Vu Thuy Khanh; Lu, Mengji; Yang, Dong-Liang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral Immunity
    In: Frontiers in Immunology Jg. 12 (2021) 722027
  • Lin, Yong; Yuan, Jun; Long, Quanxin; Hu, Jieli; Deng, Haijun; Zhao, Zhenyu; Chen, Juan; Lu, Mengji; Huang, Ailong
    Patients with SARS-CoV-2 and HBV co-infection are at risk of greater liver injury
    In: Genes & Diseases Jg. 8 (2021) Nr. 4, S. 484 - 492
  • Huang, Hongming; Rückborn, Meike; Le-Trilling, Vu Thuy Khanh; Zhu, Dan; Yang, Shangqing; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Yinping; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Trilling, Mirko; Liu, Jia
    Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist in mice
    In: European Journal of Immunology Jg. 51 (2021) Nr. 2, S. 393 - 407
  • Zhang, Hongjun; Zhou, Jiao; Xiao, Peng; Lin, Yong; Gong, Xin; Liu, Shiyan; Xu, Qingjia; Wang, Minjin; Ren, Haiyan; Lu, Mengji; Wang, Yuan; Zhu, Jing; Xie, Zhiping; Li, Huihui; Lu, Kefeng
    PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes
    In: Autophagy Jg. 17 (2021) Nr. 8, S. 1907 - 1917
  • Huang, Xuan; Zhang, Xiaoyong; Lu, Mengji
    Recent trends in the development of Toll-like receptor 7/8-targeting therapeutics
    In: Expert Opinion on Drug Discovery Jg. 16 (2021) Nr. 8, S. 869 - 880
  • Wu, Jun; Liang, Boyun; Chen, Cunrong; Wang, Hua; Fang, Yaohui; Shen, Shu; Yang, Xiaoli; Wang, Baoju; Chen, Liangkai; Chen, Qi; Wu, Yang; Liu, Jia; Yang, Xuecheng; Li, Wei; Zhu, Bin; Zhou, Wenqing; Wang, Huan; Li, Sumeng; Lu, Sihong; Liu, Di; Li, Huadong; Krawczyk, Adalbert; Lu, Mengji; Yang, Dongliang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 1813
  • Zou, Shi; Du, Yanqin; Huang, Shunmei; Chen, Mingfa; Yang, Xiaoli; Li, Sumeng; Chen, Yingshan; Han, Meihong; Li, Jia; Yu, Qing; Littwitz-Salomon, Elisabeth; Huang, Hongming; Trilling, Mirko; Liu, Shi; Pei, Rongjuan; Liu, Jia; Wang, Baoju; Zheng, Xin; Lu, Mengji; Dittmer, Ulf; Sun, Shuilin; Yang, Dongliang; Wu, Jun
    Simultaneous or Prior Activation of Intrahepatic Type I Interferon Signaling Leads to Hepatitis B Virus Persistence in a Mouse Model
    In: Journal of Virology Jg. 95 (2021) Nr. 24, e00034-21
  • Du, Yanqin; Anastasiou, Olympia E.; Strunz, Benedikt; Scheuten, Janina; Bremer, Birgit; Kraft, Anke; Kleinsimglinhaus, Karolina; Todt, Daniel; Bröring, Ruth; Hardtke-Wolenski, Matthias; Wu, Jun; Yang, Dongliang; Dittmer, Ulf; Lu, Mengji; Cornberg, Markus; Björkström, Niklas K.; Khera, Tanvi; Wedemeyer, Heiner
    The impact of hepatitis B surface antigen on natural killer cells in patients with chronic hepatitis B virus infection
    In: Liver International Jg. 41 (2021) Nr. 9, S. 2046 - 2058
  • Zhao, Zhenyu; Lu, Kefeng; Mao, Binli; Liu, Shi; Trilling, Mirko; Huang, Ailong; Lu, Mengji; Lin, Yong
    The interplay between emerging human coronavirus infections and autophagy
    In: Emerging Microbes & Infections Jg. 10 (2021) Nr. 1, S. 196 - 205
  • Wang, Xueyu; Wei, Zhiqiang; Jiang, Yongfang; Meng, Zhongji; Lu, Mengji
    mTOR Signaling : The Interface Linking Cellular Metabolism and Hepatitis B Virus Replication
    In: Virologica Sinica Jg. 36 (2021) Nr. 6, S. 1303 - 1314
  • Wang, Shichuan; Trilling, Mirko; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Zheng, Xin; Yang, Dongliang; Liu, Jia
    A Crowned Killer’s Résumé : Genome, Structure, Receptors, and Origin of SARS-CoV-2
    In: Virologica Sinica (2020)
  • Wang, Xueyu; Lin, Yong; Kemper, Thekla; Chen, Jieliang; Yuan, Zhenghong; Liu, Shi; Zhu, Ying; Bröring, Ruth; Lu, Mengji
    AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy
    In: Cellular Microbiology Jg. 22 (2020) Nr. 2, S. e13131
  • Weng, Zhihong; Chen, Qiaosen; Li, Sumeng; Li, Huadong; Zhang, Qian; Lu, Sihong; Wu, Li; Xiong, Leiqun; Mi, Bobin; Liu, Di; Lu, Mengji; Yang, Dongliang; Jiang, Hongbo; Zheng, Shaoping; Zheng, Xin
    ANDC : An early warning score to predict mortality risk for patients with Coronavirus Disease 2019
    In: Journal of Translational Medicine Jg. 18 (2020) Nr. 1, S. 328
  • Li, Qian; Wang, Jun; Lu, Mengji; Qiu, Yuanwang; Lu, Hongzhou
    Acute-on-Chronic Liver Failure From Chronic-Hepatitis-B, Who Is the Behind Scenes
    In: Frontiers in Microbiology Jg. 11 (2020) S. 583423
  • Meng, Zhongji; Chen, Yuanyuan; Lu, Mengji
    Advances in Targeting the Innate and Adaptive Immune Systems to Cure Chronic Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 10 (2020) S. 3217
  • Han, Mingfeng; Xu, Mengyuan; Zhang, Yafei; Liu, Zhongping; Li, Shasha; He, Tengfei; Li, Jinsong; Gao, Yong; Liu, Wanjun; Li, Tuantuan; Chen, Zixiang; Huang, Xin; Cheng, Guoling; Wang, Jun; Dittmer, Ulf; Witzke, Oliver; Zou, Guizhou; Li, Xiuyong; Lu, Mengji; Zhang, Zhenhua
    Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity
    In: Medical Microbiology and Immunology Jg. 209 (2020) S. 657 - 668
  • Xu, Ling; Liu, Jia; Lu, Mengji; Yang, Dongliang; Zheng, Xin
    Author response to Letter to the Editor : Potential implications of COVID-19 in non-alcoholic fatty liver disease
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    Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD1/PD-L1 blockade in chronic hepadnaviral infection
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S160
  • Chen, Ming-Fa; Lin, Yong; Xia, You-Chen; Sun, Chan; Feng, Xue-Mei; Lu, Mengji; Yang, Dong-Liang; Wu, Jun
    Establishment and application of hepatitis B virus persistent replication model in IFNAR⁻/⁻ mouse
    In: Journal of Huazhong University of Science and Technology Jg. 33 (2013) Nr. 3, S. 392 - 397
  • Chen, Jieliang; Wu, Min; Zhang, Xiaonan; Zhang, Wen; Zhang, Zhanqing; Chen, Lixian; He, Jing; Zheng, Ye; Chen, Cuncun; Wang, Fan; Hu, Yunwen; Zhou, Xiaohui; Wang, Cong; Xu, Yang; Lu, Mengji; Yuan, Zhenghong
    Hepatitis B virus polymerase impairs interferon-α-induced STA T activation through inhibition of importin-α5 and protein kinase C-δ
    In: Hepatology Jg. 57 (2013) Nr. 2, S. 470 - 482
  • Li, Lei; Shen, Hong; Li, Anyi; Zhang, Zhenhua; Wang, Baoju; Wang, Junzhong; Zheng, Xin; Wu, Jun; Yang, Dongliang; Lu, Mengji; Song, Jingjiao
    Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B
    In: Virology Journal Jg. 10 (2013) 214
  • Yang, Yinke; Zhang, Xiaoyong; Zhang, Chunyan; Tao, Yuanqing; Fan, Wei; Wang, Zhongdong; Wang, Hu; Lu, Mengji; Yang, Dongliang; Fiedler, Melanie; Wang, Baoju
    Molecular characterization of woodchuck CD4 (wCD4) and production of a depletion monoclonal antibody against wCD4
    In: Molecular Immunology Jg. 56 (2013) Nr. 1/2, S. 64 - 71
  • Zhu, B.; Yang, D.; Wang, Z.; Lu, Mengji; Fan, W.; Tao, Y.; Wang, B.; Huang, S.; Song, Z.; Zhu, Z.; Wang, H.
    Nucleoside analogues alone or combined with vaccination prevent WHV infection and induce protective immunity IMMUNITY : new strategy for HBV post-exposure prophylaxis
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S164 - S165
  • Lu, Mengji; Wang, B.; Pan, D.; Wu, W.; Xu, Y.; Yang, D.; Lin, Y.
    Persistence of chimeric Hepatitis B viruses in the hydrodynamic injection mouse model
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S165
  • Qin, Bo; Pei, RongJuan; He, TingTing; Huang, ZhaoHui; Pan, GuoShao; Tu, ChunYu; Lu, Mengji; Chen, XinWen
    Polymerase mutations rtN238R, rtT240Y and rtN248H of hepatitis B virus decrease susceptibility to adefovir
    In: Chinese Science Bulletin Jg. 58 (2013) Nr. 15, S. 1760 - 1766
  • Fiedler, Melanie; Kosinska, Anna; Schumann, Alexandra; Brovko, Olena; Walker, Andreas; Lu, Mengji; Johrden, Lena; Mayer, Anja; Wildner, Oliver; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects from hepatitis D virus (HDV) infection after simultaneous infection with HDV and woodchuck hepatitis virus
    In: Journal of Virology Jg. 87 (2013) Nr. 13, S. 7708 - 7716
  • Meng, Zhongji; Zhang, Xiaoyong; Wu, Jun; Pei, Rongjuan; Xu, Yang; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji
    RNAi induces innate immunity through multiple cellular signaling pathways
    In: PLoS ONE Jg. 8 (2013) Nr. 5, e 64708
  • Huang, S.; Wang, J.; Song, Z.; Yang, D.; Zhu, Z.; Feng, X.; Lu, Mengji; Zhu, B.; Wang, B.
    Rapamycin modulates the course of Hepatitis B Virus (HBV) infection in hydrodynamic injection mouse model : the role of Treg in HBV persistence
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S156 - S157
  • Lu, Mengji; Zhang, X.; Deng, W.; Li, B.; Hou, J.; Liu, H.
    Regulation of HBV replication bymicroRNA-449a through targeting creb5 in hepatoma cells
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S165
  • Liu, Jia; Jiang, Min; Ma, Zhiyong; Dietze, Kirsten; Zelinskyy, Gennadiy; Yang, Dongliang; Dittmer, Ulf; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro
    In: The Journal of Immunology (JI) Jg. 191 (2013) Nr. 12, S. 6178 - 6190
  • Qin, Bo; Budeus, Bettina; Cao, Liang; Wu, Chunchen; Wang, Yun; Zhang, Xiaoyong; Rayner, Simon; Hoffmann, Daniel; Lu, Mengji; Chen, Xinwen
    The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    In: Antiviral Research Jg. 97 (2013) Nr. 2, S. 93 - 100
  • Wu, Chunchen; Shi, Hui; Wang, Yun; Lu, Mengji; Xu, Yang; Chen, Xinwen
    A case of hepatitis B reactivation due to the hepatitis B virus escape mutant in a patient undergoing chemotherapy
    In: Virologica Sinica Jg. 27 (2012) Nr. 6, S. 369 - 372
  • Wu, Chunchen; Deng, Wanyu; Deng, Liu; Cao, Liang; Qin, Bo; Li, Songxia; Wang, Yun; Pei, Rongjuan; Yang, Dongliang; Lu, Mengji; Chen, Xinwen
    Amino acid substitutions at positions 122 and 145 of hepatitis B virus surface antigen (HBsAg) determine the antigenicity and immunogenicity of HBsAg and influence in vivo HBsAg clearance
    In: Journal of Virology Jg. 86 (2012) Nr. 8, S. 4658 - 4669
  • Xu, Song; Pei, Rongjuan; Guo, Min; Han, Qingxia; Lai, Juan; Wang, Yun; Wu, Chunchen; Zhou, Yuan; Lu, Mengji; Chen, Xinwen
    Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly
    In: Journal of Virology Jg. 86 (2012) Nr. 23, S. 13025 - 13037
  • Kosinska, Anna D.; Johrden, Lena; Zhang, Ejuan; Fiedler, Melanie; Mayer, Anja; Wildner, Oliver; Lu, Mengji; Roggendorf, Michael
    DNA Prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model
    In: Journal of Virology Jg. 86 (2012) Nr. 17, S. 9297 - 9310
  • Sallam, T.A.; Raja'a, Y.A.; Bahaj, S.; Al-Shami, A.M.; Lu, Mengji; Roggendorf, Michael; Tong, C.Y.W.
    Hepatitis B virus carrier rate, prevalence and susceptibility and impact of immunization program among households in the city of Taiz, Yemen
    In: Vaccine Jg. 30 (2012) Nr. 37, S. 5564 - 5568
  • Zhu, Wenbo; Wu, Chunchen; Deng, Wanyu; Pei, Rongjun; Wang, Yun; Cao, Liang; Qin, Bo; Lu, Mengji; Chen, Xinwen
    Inhibition of the HCV Core Protein on the Immune Response to HBV Surface Antigen and on HBV Gene Expression and Replication In Vivo
    In: PLoS ONE Jg. 7 (2012) Nr. 9, S. e45146
  • Fan, Hebin; Zhu, Zhenni; Wang, Yang; Zhang, Xiaoyong; Lu, Yinping; Tao, Yuanqing; Fan, Wei; Wang, Zhongdong; Wang, Hu; Roggendorf, Micheal; Lu, Mengji; Wang, Baoju; Yang, Dongliang
    Molecular characterization of the type I IFN receptor in two woodchuck species and detection of its expression in liver samples from woodchucks infected with woodchuck hepatitis virus (WHV)
    In: Cytokine Jg. 60 (2012) Nr. 1, S. 179 - 185
  • Jiang, Min; Liu, Jia; Zhang, Ejuan; Meng, Zhongji; Wang, Baoju; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Molecular characterization of woodchuck interleukin-10 receptor and enhanced function of specific T cells from chronically infected woodchucks following its blockade
    In: Comparative Immunology, Microbiology and Infectious Diseases Jg. 35 (2012) Nr. 6, S. 563 - 573
  • Zhang, Xiaoyong; Kraft, Anke; Bröring, Ruth; Schlaak, Jörg Friedrich; Dittmer, Ulf; Lu, Mengji
    Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections
    In: Expert Opinion on Drug Discovery Jg. 7 (2012) Nr. 7, S. 597 - 611
  • Yang, Yinke; Wang, Baoju; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Prokaryotic expression of woodchuck cytotoxic T lymphocyte antigen 4 (wCTLA-4) and preparation of polyclonal antibody to wCTLA-4
    In: Protein Expression and Purification Jg. 81 (2012) Nr. 2, S. 181 - 185
  • Pei, Rongjuan; Zhang, Xiaoyong; Xu, Song; Meng, Zhongji; Roggendorf, Michael; Lu, Mengji; Chen, Xinwen
    Regulation of Hepatitis C virus replication and gene expression by the MAPK-ERK pathway
    In: Virologica Sinica Jg. 27 (2012) Nr. 5, S. 278 - 285
  • Zhang, Xiaoyong; Ma, Zhiyong; Liu, Hongyan; Liu, Jia; Meng, Zhongji; Bröring, Ruth; Yang, Dongliang; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Role of Toll-like receptor 2 in the immune response against hepadnaviral infection
    In: Journal of Hepatology Jg. 57 (2012) Nr. 3, S. 522 - 528
  • Fang, Haoshu; Liu, Anding; Dirsch, Olaf; Sun, Jian; Jin, Hao; Lu, Mengji; Yang, Dongliang; Dahmen, Uta
    Serum LBP levels reflect the impaired synthetic capacity of the remnant liver after partial hepatectomy in rats
    In: Journal of Immunological Methods Jg. 382 (2012) Nr. 1-2, S. 68 - 75
  • Bröring, Ruth; Montag, Mario; Jiang, Min; Lu, Mengji; Sowa, Jan-Peter; Kleinehr, Kathrin; Gerken, Guido; Schlaak, Jörg Friedrich
    Corticosteroids shift the Toll-like receptor response pattern of primary-isolated murine liver cells from an inflammatory to an anti-inflammatory state
    In: International Immunology Jg. 23 (2011) Nr. 9, S. 537 - 544
  • Yin, Ying; Wu, Chunchen; Song, Jingjiao; Wang, Junzhong; Zhang, Ejuan; Liu, Hongyan; Yang, Dongliang; Chen, Xinwen; Lu, Mengji; Xu, Yang
    DNA Immunization with Fusion of CTLA-4 to Hepatitis B Virus (HBV) Core Protein Enhanced Th2 Type Responses and Cleared HBV with an Accelerated Kinetic
    In: PLoS ONE Jg. 6 (2011) Nr. 7, S. 0022524
  • Zhang, Zhenhuan; Li, Lei; Zhao, Xiping; Glebe, Dieter; Bremer, Corinna M.; Zhang, Zheng Mao; Tian, Yong Jun; Wang, Bao Ju; Yang, Yinke; Gerlich, Wolfram Hubert; Roggendorf, Michael; Li, Xu; Lu, Mengji; Yang, Dong Liang
    Elimination of hepatitis B virus surface antigen and appearance of neutralizing antibodies in chronically infected patients without viral clearance
    In: Journal of Viral Hepatitis Jg. 18 (2011) Nr. 6, S. 424 - 433
  • Wang, Bao-Ju; Tian, Yong-Jun; Meng, Zhong-Ji; Jiang, Min; Wei, Bo-Qing; Tao, Yuan-Qing; Fan, Wei; Li, An-Yi; Bao, Jun-Jie; Li, Xin-Yu; Zhang, Zheng-Mao; Wang, Zhong-Dong; Wang, Hu; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Establishing a new animal model for hepadnaviral infection : Susceptibility of Chinese Marmota-species to woodchuck hepatitis virus infection
    In: Journal of General Virology Jg. 92 (2011) Nr. 3, S. 681 - 691
  • Pei, Rongjuan; Chen, Honghe; Lu, Lu; Zhu, Wandi; Beckebaum, Susanne; Cicinnati, Vito; Lu, Mengji; Chen, Xinwen
    Hepatitis C virus infection induces the expression of amphiregulin, a factor related to the activation of cellular survival pathways and required for efficient viral assembly
    In: Journal of General Virology Jg. 92 (2011) Nr. 10, S. 2237 - 2248
  • Wang, Bao-Ju; Bao, Jun-Jie; Wang, Jun-Zhong; Wang, Yang; Jiang, Min; Xing, Ming-You; Zhang, Wan-Guang; Qi, Jun-Ying; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma
    In: World Journal of Gastroenterology Jg. 17 (2011) Nr. 28, S. 3322 - 3329
  • Liu, Min; Hao, Youhua; Ding, Honghui; Yang, Dongliang; Lu, Mengji
    Interleukin-10 is expressed in HepG2.2.15 cells and regulated by STAT1 pathway
    In: Journal of Huazhong University of Science and Technology Jg. 31 (2011) Nr. 5, S. 625 - 631
  • Zhang, Xiaoyong; Zhang, Ejuan; Ma, Zhiyong; Pei, Rongjuan; Jiang, Min; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1
    In: Hepatology Jg. 53 (2011) Nr. 5, S. 1476 - 1485
  • Bröring, Ruth; Lu, Mengji; Schlaak, Jörg Friedrich; Schlaak, Joerg F.
    Role of Toll-like receptors in liver health and disease
    In: Clinical Science Jg. 121 (2011) Nr. 10, S. 415 - 426
  • Xu, Yang; Köck, Josef; Lu, Yinping; Yang, Dongliang; Lu, Mengji; Zhao, Xiping
    Suppression of hepatitis B virus replication in Tupaia hepatocytes by tumor necrosis factor alpha of Tupaia belangeri
    In: Comparative Immunology, Microbiology and Infectious Diseases Jg. 34 (2011) Nr. 4, S. 361 - 368
  • Zhang, Ejuan; Zhang, Xiaoyong; Liu, Jia; Wang, Baoju; Tian, Yongjun; Kosinska, Anna D.; Ma, Zhiyong; Xu, Yang; Dittmer, Ulf; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji
    The Expression of PD-1 Ligands and Their Involvement in Regulation of T Cell Functions in Acute and Chronic Woodchuck Hepatitis Virus Infection
    In: PLoS ONE Jg. 6 (2011) Nr. 10, S. 0026196
  • Zelinskyy, Gennadiy; Myers, Lara; Dietze, Kirsten; Gibbert, Kathrin; Roggendorf, Michael; Liu, Jia; Lu, Mengji; Kraft, Anke R.; Teichgräber, Volker; Hasenkrug, Kim J.; Dittmer, Ulf
    Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication
    In: The Journal of Immunology (JI) Jg. 187 (2011) Nr. 7, S. 3730 - 3737
  • Zhang, X.; Zhang, E.; Meng, Z.; Ma, Z.; Schlaak, Jörg Friedrich; Lu, Mengji
    110 Modulation of HBV replication and cellular gene expression by microrna-1
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S49 - S50
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Wu, J.; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    627 HBV suppresses TLR signaling and the crosstalk to the adaptive immune system in murine and human cells
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S246
  • Liu, Jia; Hu, Bin; Yang, Yan; Ma, Zhiyong; Yu, Yuan; Liu, Shenpei; Wang, Baoju; Zhao, Xiping; Lu, Mengji; Yang, Dongliang
    A new splice variant of the major subunit of human asialoglycoprotein receptor encodes a secreted form in hepatocytes
    In: PLoS ONE Jg. 5 (2010) Nr. 9,
  • Wu, Chunchen; Zhang, Xiaoyong; Tian, Zhang; Song, Jianhua; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji; Chen, Xinwen; Tian, Y.
    Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
    In: Journal of General Virology Jg. 91 (2010) Nr. 2, S. 483 - 492
  • Liu, Jia; Yang, Yan; Hu, Bin; Ma, Zhi-Yong; Huang, Hong-Ping; Yu, Yuan; Liu, Shen-Pei; Lu, Mengji; Yang, Dong-Liang
    Development of HBsAg-binding aptamers that bind HepG2.2.15 cells via HBV surface antigen
    In: Virologica Sinica Jg. 25 (2010) Nr. 1, S. 27 - 35
  • Hu, Bin; Yang, Yan; Liu, Jia; Ma, Zhiyong; Huang, Hongping; Liu, Shenpei; Yu, Yuan; Hao, Youhua; Wang, Baoju; Lu, Mengji; Yang, Dongliang
    Establishment of a functional cell line expressing both subunits of H1a and H2c of human hepatocyte surface molecule ASGPR
    In: Journal of Huazhong University of Science and Technology Jg. 30 (2010) Nr. 5, S. 556 - 561
  • Li, Yanmei; Chen, Jizheng; Wu, Chunchen; Wang, Linding; Lu, Mengji; Chen, Xinwen
    Hepatitis B virus/hepatitis C virus upregulate angiopoietin-2 expression through mitogen-activated protein kinase pathway
    In: Hepatology Research Jg. 40 (2010) Nr. 10, S. 1022 - 1033
  • Shen, Qingli; Cicinnati, Vito; Zhang, Xiaoyong; Iacob, Speranta; Weber, Frank; Sotiropoulos, Georgios; Radtke, Arnold; Lu, Mengji; Paul, Andreas; Gerken, Guido; Beckebaum, Susanne
    Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion
    In: Molecular Cancer Jg. 9 (2010) 227
  • Zhu, Wenbo; Chang, Yanzi; Wu, Chunchen; Han, Qingxia; Pei, Rongjuan; Lu, Mengji; Chen, Xinwen
    The Wild-Type Hepatitis C Virus Core Inhibits Initiation of Antigen-Specific T- and B-Cell Immune Responses in BALB/c Mice
    In: Clinical and Vaccine Immunology Jg. 17 (2010) Nr. 7, S. 1139 - 1147
  • Bröring, Ruth; Zhang, Xiaozhen; Kottilil, Shyam; Trippler, Martin; Jiang, Min; Lu, Mengji; Gerken, Guido; Schlaak, Jörg Friedrich
    The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response
    In: Gut Jg. 59 (2010) Nr. 8, S. 1111 - 1119
  • Roggendorf, Michael; Yang, D.; Lu, Mengji
    The woodchuck : A model for therapeutic vaccination against hepadnaviral infection
    In: Pathologie Biologie Jg. 58 (2010) Nr. 4, S. 308 - 314
  • Wu, Jun; Meng, Zhongji; Jiang, Min; Zhang, Ejuan; Trippler, Martin; Bröring, Ruth; Bucchi, Agnes; Krux, Frank; Dittmer, Ulf; Yang, Dongliang; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific
    In: Immunology Jg. 129 (2010) Nr. 3, S. 363 - 374
  • Lu, Mengji; Viazov, Sergey; Dittmer, Ulf; Roggendorf, Michael; aus dem Siepen, Marc
    Chronische Infektionen : ein Versagen des Immunsystems
    In: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, S. 34 - 47
  • Lu, M.; Isogawa, M.; Hilken, Gero
    Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune response in mice and woodchucks.
    In: (J. Virol.) Jg. 79 (2005) Nr. 10, S. 6368 - 6376
  • Dahmen, Uta; Dirsch, Olaf; Li, Jun; Fiedler, Melanie; Lu, Mengji; Rispeter, Kai; Picucci, Martha; Broelsch, Christoph E.; Roggendorf, Michael
    Adoptive transfer of immunity : A new strategy to interfere with severe hepatitis virus reinfection after woodchuck liver transplantation
    In: Transplantation Jg. 77 (2004) Nr. 7, S. 965 - 972
  • Fiedler, Melanie; Rödicker, Florian; Salucci, Valentina; Lu, Mengji; Aurisicchio, Luigi; Dahmen, Uta; Jun, Li; Dirsch, Olaf; Pützer, Brigitte M.; Palombo, Fabio; Roggendorf, Michael
    Helper-dependent adenoviral vector-mediated delivery of woodchuck-specific genes for alpha interferon (IFN-α) and IFN-γ : IFN-α but not IFN-γ reduces woodchuck hepatitis virus replication in chronic infection in vivo
    In: Journal of Virology Jg. 78 (2004) Nr. 18, S. 10111 - 10121
  • Zeng, X.; Weinberger, K.M.; Gehrke, R.; Isogawa, M.; Hilken, Gero; Kemper, T.; Xu, Y.; Yang, D.; Jilg, W.; Roggendorf, M.; Lu, M.
    Mutant hepatitis B virus surface antigen (HbsAg) are immunogenic but may have a change specificity.
    In: Virology Jg. 329 (2004) S. 454 - 464
  • Dahmen, Uta; Li, Jun; Dirsch, Olaf; Fiedler, Melanie; Lu, Mengji; Roggendorf, Michael; Broelsch, Christoph Erich
    A new model of hepatitis B virus reinfection : Liver transplantation in the woodchuck
    In: Transplantation Jg. 74 (2002) Nr. 3, S. 373 - 380
  • Lu, M.; Lohrengel, B.; Hilken, Gero; Kemper, T.; Roggendorf, M.
    Woodchuck gamma interferon upregulates major histocompartibility complex class I transcription but is unable to deplete woodchuck hepatitis virus replication intermediatesand RNAs in persistently infected woodchuck primary hepatocytes.
    In: (J. Virol.) Jg. 76 (2002) Nr. 1, S. 58 - 67
  • Haupt, K.; Siegel, F.; Lu, M.; Yang, D.; Hilken, Gero; Mann, K.; Roggendorf, M.; Saller, B.
    Induction of a cellular and humoral Immune response against preprocalcitonin by genetic immunization: A potential new treatment for medullary thyroid carcinoma.
    In: Endocrinology Jg. 142 (2001) Nr. 3, S. 1017 - 1023
  • Lu, M.; Hilken, Gero; Dongliang, Y.; Kemper, T.; Roggendorf, M.
    Replication of naturally occurring Woodchuck Hepatitis Virus: Deletion Mutants in primary hepatocytes cultures and after transmission to naive woodchucks.
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  • Lu, M.; Siegel, F.; Hilken, Gero; Kemper, T.; Roggendorf, M.
    DNA vaccination against hepadnavirus in the woodchuck model: priming immune response to woodchuck hepatitis virus core antigen protects against WHV infections.
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  • Haupt, K.; Siegel, F.; Lu, M.; Saller, B.; Hilken, Gero; Yang, D.; Mann, K.; Roggendorf, M.
    The GM-CSF gene enhances the immune response induced by DNA immunization against the tumor associated antigen calcitonin.
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  • Lu, Mengji; Hilken, Gero; Kruppenbacher, Johannes; Reimann, Jörg; Roggendorf, Michael
    Immunization of Woodchucks with Plasmids Expressing Woodchuck Hepatitis Virus (WHV) Core Antigen and Surface Antigen Suppresses WHV Infection
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  • Vorworte / Nachworte

  • Meng, Zhongji; Liu, Jia; Kosinska, Anna D.; Lu, Mengji
    Editorial: Targeting the Immune System to Treat Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 13 (2022) 868616
  • Abstracts

  • Liang, Yaojie; Luo, Xufeng; Schefczyk, Stefan; Baba, Hideo; Lu, Mengji; Bröring, Ruth;
    Expression of hepatitis B surface antigen in vivo and in vitro induces endoplasmic reticulum stress, impairs autophagy and promotes proliferation
    The International Liver Congress 2022 ; 22-26 June 2022, London, UK,
    In: Journal of Hepatology Jg. 77 (2022) Nr. Supplement 1: Abstracts of The International Liver CongressTM 2022, S. S643 - S644
  • Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Hasenberg, Mike; Walkenfort, Bernd; Trippler, Martin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut; Bröring, Ruth;
    Hepatitis B virus-replicating transgenic mice exhibit a functional but restricted responsiveness to exogenous Tlr3 and Rig-I stimuli
    The International Liver Congress 2022 ; 22-26 June 2022, London, UK,
    In: Journal of Hepatology Jg. 77 (2022) Nr. Supplement 1: Abstracts of The International Liver CongressTM 2022, S. S264 - S265
  • Luo, Xufeng; Zhang, Rui; Liang, Yaojie; Schefczyk, Stefan; Liu, Shi; Baba, Hideo; Lange, Christian; Wedemeyer, Heiner; Lu, Mengji; Bröring, Ruth;
    Hippo inactivation drives BMI1-associated proliferative hepatocarcinogenesis in chronic hepatitis B virus infection
    The International Liver Congress 2022 ; 22-26 June 2022, London, UK,
    In: Journal of Hepatology Jg. 77 (2022) Nr. Supplement 1: Abstracts of The International Liver CongressTM 2022, S. S642
  • Zhenhua, Zhu; Trippler, Martin; Real, Catherine Isabell; Werner, Melanie; Kemper, Thekla; Baba, Hideo Andreas; Treckmann, Jürgen-Walter; Paul, A.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji; Bröring, Ruth
    Hepatitis B virus entry in primary human hepatocytes initiates toll-like receptor 2-dependent immune signaling
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 793
  • Anastasiou, Olympia E.; Westhaus, Sandra; Anspach, Marie Christine; Timmer, Lejla; Susser, Simone; Sarrazin, Christoph; Gerken, Guido; Keitel, Verena; Wedemeyer, Heiner; Lu, Mengji; Stindt, Jan; Ciesek, Sandra
    Sodium taurocholate cotransporting popypeptide variants modulate HDV entry according to their function as a bile acid transporter but do not influence the antiviral effect of Myrcludex-B
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 781
  • Zhang, X.; Ge, J.; Huang, Z.; Sun, J.; Lu, Mengji; Hou, J.
    Expression and Function of Toll-Like Receptor 7 in Chronic Hepatitis B Patients Links to Antiviral Effect of PEG-IFN-A-2A Therapy
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S380 - S381
  • Liu, J.; Yang, D.; Lu, Mengji
    HBV Strengthens Intrahepatic Myeloid-Derived Cells Mediated T Cell Tolerance through TLR1/2 Induced Kupffer Cell Expansion and IL-10 Production
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S515
  • Bröring, Ruth; Zhang, Z.; Trippler, M.; Real, C.; Werner, M.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji
    Hepatitis B virus activates toll-like receptor 2 signaling upon infection of primary human hepatocytes
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S394
  • Liu, J.; Xu, C.; Zheng, X.; Lu, Mengji; Yang, D.
    Increased TLR2 Expression in Peripheral CD4+T Cells Promotes TH17 Cells Responses and is Associated with Disease Aggravation of HBV-Related Acute-on-Chronic Liver Failure
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S307
  • Zhang, X.; Liu, H.; Wang, B.; Ma, Z.; Zhang, J.; Yang, D.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Epigenetic control of Hepatitis B virus replication and farnesoid X receptor alpha expression by histone deacetylases 3
    In: Journal of Hepatology Jg. 56 (2012) Nr. Suppl. 2, S. S17
  • Liu, H.; Zhang, J.; Zhang, X.; Bleekmann, B.; Kemper, T.; Roggendorf, Michael; Dittmer, Ulf; Lu, Mengji
    Genomic analysis of the host response to hepatitis b virus infection
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S187
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Hepatitis B virus surface antigen suppresses innate and adaptive immune responses of murine and human liver cells
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S174
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Wu, J.; Zhang, E.; Zhang, X.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    TLR-3 dependent immunological properties of liver cells are controlled by anti-inflammatory cytokines through modulation of MIR-155 expression
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S302 - S303
  • Liu, J.; Jiang, M.; Ma, Z.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand stimulated mouse liver endothelial cells produce IL-12 and trigger CD8+ T-Cell immunity
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S311
  • Ma, Z.; Zhang, E.; Zhang, X.; Liu, J.; Lin, Y.; Wu, J.; Kosinska, A.; Dittmer, Ulf; Roggendorf, Michael; Yang, D.; Lu, Mengji
    TLR2 ligand PAM3CSK4 inhibits peptide-induced deletion of CD8 T cells to viral antigens in mouse model
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S312
  • Wu, J.; Chen, M.; Xia, Y.; Sun, C.; Lin, Y.; Wang, J.; Guo, Y.; Wang, B.; Song, J.; Lu, Mengji; Yang, D.
    The clearance of Hepatitis B virus (HBV) n hydrodynamik injection mouse model by polyinosinic-polycytidylic acid (POLYIC) treatment is dependent on interferon-gamma
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S319
  • Meng, Z.; Zhang, E.; Zhang, X.; Kosinska, A.; Xu, Y.; Yang, D.; Zhou, T.; Mason, W.; Roggendorf, Michael; Lu, Mengji
    DNA vaccination induces WHS/CAG specific T Cell immune responses in the newly constructed WHV transgenic mouse model
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S441
  • Wang, J. Z.; Wang, B. J.; Huang, S. M.; Wu, J.; Zhu, Z. N.; Zhu, B.; Ding, H. H.; Feng, X. M.; Yin, Y.; Roggendorf, Michael; Lu, Mengji; Yang, D. L.
    Immunosuppression modulates the course of hepatitis B virus (HBV) infection in hydrodynamic injection mouse model
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S127
  • Zhang, X.; Ma, Z.; Wu, C.; Zhang, E.; Bröring, Ruth; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of HBV replication by cell cycle and differentiation related micrornas
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S448 - S449
  • Fiedler, Melanie; Schumann, A.; Kosinska, A.; Lu, Mengji; Johrden, L.; Wildner, O.; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects woodchucks from hepatitis D virus infection
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S439
  • Xu, L.; Beckebaum, Susanne; Wu, G.; Zhang, X.; Lu, Mengji; Iacob, S.; Paul, Andreas; Gerken, Guido; Cicinnati, Vito R.;
    The putative tumor suppressor microrna-101 negatively regulates the polycomb group protein enhancer of zeste homolog 2 (EZH2) in human hepatocellular carcinoma cells
    46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011,
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S110
  • Jiang, M.; Wu, J.; Zhang, E.; Meng, Z.; Trippler, M.; Bröring, Ruth; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    446 HCV/TLR3- dependent innate and adaptive immune functions of non-parenchymal liver cells are controlled by interleukin-10 and transforming growth factor beta
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S180
  • Zhang, E.; Kosinska, A.; Zhang, X.; Meng, Z.; Xu, Y.; Yang, D.; Roggendorf, Michael; Lu, Mengji;
    637 Enhanced TH2 type immune response in DNA immunization by fusion of WCTLA-4 to woodchuck hepatitis core antigen
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    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S249
  • Roggendorf, Michael; Ke, X.Y.; Yang, Y.; Yang, D.L.; Zhang, X.Y.; Meng, Z.J.; Kemper, T.; Wang, Q.J.; Lu, Mengji; Lu, L.;
    OL-022 The effect of double-stranded DNA on replication of hepatitis B virus and cellular signalling
    Fourth Ditan International Conference on Infectious Diseases - Changing Face of Infectious Diseases. 15-18 July 2010, Beijing,
    In: International Journal of Infectious Diseases Jg. 14 (2010) Nr. Suppl. 2, S. S10
  • Lu, Mengji; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, Michael
    Protektion von Woodchucks gegen Woodchuckhepatitisvirus (WHV)-Infektion durch DNA-Immunisierung mit WHcAg- und WHsAg-exprimierenden Plasmiden
    In: Jahrestagung Gesellschaft für Virologie, Regensburg 2.-5. März 1998,: Abstracts / Jahrestagung Gesellschaft für Virologie, Regensburg 2.-5. März 1998 (1998) S. 30
  • Beiträge in Sammelwerken und Tagungsbänden

  • Liu, Jia; Huang, Xuan; Werner, Melanie; Bröring, Ruth; Yang, Dongliang; Lu, Mengji
    Advanced Method for Isolation of Mouse Hepatocytes, Liver Sinusoidal Endothelial Cells, and Kupffer Cells
    In: Hepatitis B Virus: Methods and Protocols / Guo, Haitao; Cuconati, Andrea (Hrsg.) 2017, S. 249 - 258
  • Bauer, Dirk; Wasmuth, Susanne; Lu, Mengji; Heiligenhaus, Arnd
    Particle-mediated administration of plasmid DNA on corneas of BALB/c mice
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  • Vorträge

  • Lu, Mengji; Hilken, Gero; Yang, D.; Roggendorf, Michael;
    Replikation von Deletionsmutanten des Woodchuck Hepatitis Virus (WHV) in primären Woodchuck Hepatitis Kulturen und in vivo nach einer Übertragung
    38. Tagung der GV-SOLAS, September 2000, Essen,
    (2000)