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ZMB/ICCE
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Universitätsstr 2
45117 Essen
45117 Essen
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S05 R02 H82
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Wissenschaftliche/r Mitarbeiter/in, Zentrum für Medizinische Biotechnologie
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chainsIn: The EMBO Journal, Jg. 44, 2025, Nr. 18, S. 5086 – 5111DOI (Open Access)
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Cyanostyryl-Guanidiniocarbonyl-Pyrrole Amphiphiles : From Aggregation-Induced Emission to Photodimerization, Self-Assembly, and BioimagingIn: ChemPlusChem, 2025, in pressDOI (Open Access)
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Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasionIn: Molecular Biology of the Cell, Jg. 36, 2025, Nr. 11DOI (Open Access)
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The serine protease HTRA1 targets tau fibrils and provides a proteolytic barrier against pathogenic protein conformationsIn: The Journal of Biological Chemistry (JBC), Jg. 301, 2025, Nr. 10, 110729DOI, Online Volltext (Open Access)
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Lysosomal damage sensing and lysophagy initiation by SPG20-ITCHIn: Molecular Cell, 2024, S. 1556 – 1569.e10DOI, Online Volltext (Open Access)
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Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicityIn: Journal for ImmunoTherapy of Cancer, Jg. 10, 2022, Nr. 6, e003863DOI (Open Access)
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The Taspase1/Myosin1f-axis regulates filopodia dynamicsIn: iScience, Jg. 25, 2022, Nr. 6, 104355DOI, Online Volltext (Open Access)
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MTBP phosphorylation controls DNA replication origin firingIn: Scientific Reports, Jg. 11, 2021, Nr. 1, 4242DOI, Online Volltext (Open Access)
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A pH-sensitive fluorescent protein sensor to follow the pathway of calcium phosphate nanoparticles into cellsIn: Acta Biomaterialia, Jg. 111, 2020, S. 406 – 417
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Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerizationIn: Biological Chemistry, Jg. 401, 2020, Nr. 8, S. 955 – 968DOI (Open Access)
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Calcium phosphate nanoparticle-mediated transfection in 2D and 3D mono- and co-culture cell modelsIn: Acta Biomaterialia, Jg. 84, 2019, S. 391 – 401
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VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscleIn: Autophagy, Jg. 15, 2019, Nr. 6, S. 1082 – 1099DOI (Open Access)
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An excitable Rho GTPase signaling network generates dynamic subcellular contraction patternsIn: The Journal of Cell Biology (JCB), Jg. 216, 2017, Nr. 12, S. 4271 – 4285DOI (Open Access)
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Avidin-conjugated calcium phosphate nanoparticles as a modular targeting system for the attachment of biotinylated molecules in vitro and in vivoIn: Acta Biomaterialia, Jg. 57, 2017, S. 414 – 425
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Delivery of the autofluorescent protein R-phycoerythrin by calcium phosphate nanoparticles into four different eukaryotic cell lines (HeLa, HEK293T, MG-63, MC3T3) : Highly efficient, but leading to endolysosomal proteolysis in HeLa and MC3T3 cellsIn: PLoS ONE, Jg. 12, 2017, Nr. 6, S. e0178260DOI, Online Volltext (Open Access)
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VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagyIn: The EMBO Journal, Jg. 36, 2017, Nr. 2, S. 135 – 150DOI (Open Access)
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VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break RepairIn: Molecular Cell, Jg. 64, 2016, Nr. 1, S. 189 – 198DOI (Open Access)
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FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibersIn: Journal of Cell Science, Jg. 127, 2014, Nr. 7, S. 1379 – 1393DOI (Open Access)
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Targeted degradation of USP7 in solid cancer cells reveals disparate effects of deubiquitinase inhibition vs. acute protein depletion2025DOI, Online Volltext (Open Access)
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A non-autonomous protein quality control mechanism targeting tau aggregate propagation2024DOI (Open Access)
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Sharing, storing and analysing cell image data in a Collaborative Research Centre using OMERO
Data Steward goes Germany 2023, 25.-26.09.2023, Dresden,2023DOI (Open Access)