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Wissenschaftliche/r Mitarbeiter/in, Institut für Transfusionsmedizin
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WiSe 2025
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SoSe 2025
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WiSe 2023
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SoSe 2023
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Recruiting refugees and migrants as potential hematopoietic stem cell donors to serve patients of comparable ethnicities with rare human leucocyte antigen patterns : The BluStar.NRW project in North Western GermanyIn: Transplant Immunology, Jg. 82, 2024, 101985DOI (Open Access)
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Relevance of donor-specific HLA antibodies in hematopoietic cell transplantationIn: Best Practice & Research Clinical Haematology, Jg. 37, 2024, Nr. 3, 101576DOI (Open Access)
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Chimärismusanalyse nach Stammzelltransplantation mit hochsensitiven MethodenIn: Transfusionsmedizin, Jg. 12, 2022, Nr. 04, S. 227 – 232
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Cumulative mean fluorescent intensities of HLA specific antibodies predict antibody mediated rejections after kidney transplantationIn: HLA: Immune Response Genetics (Human Leukocyte Antigens), Jg. 100, 2022, Nr. 6, S. 553 – 562DOI (Open Access)
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Cellular immunity in COVID-19 convalescents with PCR-confirmed infection but with undetectable SARS-CoV-2-Specific IgGIn: Emerging Infectious Diseases (EID), Jg. 27, 2021, Nr. 1, S. 122 – 129DOI (Open Access)
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Characterization of follicular T helper cells and donor-specific T helper cells in renal transplant patients with de novo donor-specific HLA-antibodiesIn: Clinical Immunology, Jg. 226, 2021, S. 108698
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Convalescent plasma treatment of critically ill intensive care COVID-19 patientsIn: Transfusion, Jg. 61, 2021, Nr. 5, S. 1394 – 1403DOI (Open Access)
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Protocol liver biopsies in stable long-term pediatric liver transplant recipients: risk or benefit?In: European Journal of Gastroenterology & Hepatology, Jg. 33, 2021, Nr. Suppl 1, S. e223 – e232
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Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout lifeIn: Journal of Experimental Medicine (JEM), Jg. 218, 2021, Nr. 4, S. e20201952DOI (Open Access)
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HLA class II donor specific antibodies are associated with graft cirrhosis after liver transplant independent of the mean fluorescence intensity levelIn: BMC Gastroenterology, Jg. 20, 2020, Nr. 1, S. 288DOI, Online Volltext (Open Access)
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Multiple knockout of classical HLA Class II β-chains by CRISPR/Cas9 genome editing driven by a single guide RNAIn: The Journal of Immunology (JI), Jg. 202, 2019, Nr. 6, S. 1895 – 1903
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Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population LevelIn: Gastroenterology, Jg. 156, 2019, Nr. 6, S. 1820 – 1833DOI (Open Access)
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Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDVIn: Journal of Hepatology, Jg. 70, 2019, Nr. Suppl. 1, S. e21
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A Single-Nucleotide Polymorphism Upstream of the HLA-C Locus Is Associated With an Anti-Hepatitis C Virus-Seronegative State in a High-Risk Exposed CohortIn: The Journal of Infectious Diseases (JID), Jg. 218, 2018, Nr. 12, S. 2016 – 2019DOI (Open Access)
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Adoptive transfer of cellular immunity against cytomegalovirus by virus-specific lymphocytes from a third-party family donorIn: Bone Marrow Transplantation, Jg. 53, 2018, Nr. 10, S. 1351 – 1355
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Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cellsIn: Journal of Virology, Jg. 92, 2018, Nr. 13, e01891-17DOI, Online Volltext (Open Access)
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Author Correction : Glomerulocapillary miRNA response to HLA-class I antibody in vitro and in vivoIn: Scientific Reports, Jg. 8, 2018, Nr. 1, S. 6003DOI (Open Access)
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Effect of ABO incompatibility on T-cell flow cytometry cross-match results prior to living donor kidney transplantationIn: Cytometry Part B: Clinical Cytometry, Jg. 94, 2018, Nr. 4, S. 623 – 630DOI, Online Volltext (Open Access)
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Exploiting cutting-edge technologies to analyze loss of HLA in a multicentric cohort of post-transplantation relapsesSTUDY : results from the Hlaloss globalIn: Haematologica / The Hematology Journal, Jg. 103, 2018, Nr. S3, XV Congress of the Italian Society of Experimental Hematology Rimini, Italy, October 18-20, 2018
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Pretransplant serum BAFF levels are associated with pretransplant HLA immunization and renal allograft survivalIn: Transplant Immunology, Jg. 47, 2018, S. 10 – 17
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Clinical utility of quantitative PCR for chimerism and engraftment monitoring after allogeneic stem cell transplantation for hematologic malignanciesIn: Biology of Blood and Marrow Transplantation, Jg. 23, 2017, Nr. 10, S. 1658 – 1668
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Die durchflusszytometrische Verträglichkeitsprobe – sensitivere Diagnostik zur Prädiktion von TransplantatabstoßungenIn: Transfusionsmedizin, Jg. 7, 2017, Nr. 4, S. 233 – 237
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Glomerulocapillary miRNA response to HLA-class i antibody in vitro and in vivoIn: Scientific Reports, Jg. 7, 2017, Nr. 1, S. 14554DOI (Open Access)
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HLA-Bw4 80(T) and multiple HLA-Bw4 copies combined with KIR3DL1 associate with spontaneous clearance of HCV infection in people who inject drugsIn: Journal of Hepatology, Jg. 67, 2017, Nr. 3, S. 462 – 470DOI, Online Volltext (Open Access)
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Humoral and Cellular Responses to a Single Dose of Fendrix in Renal Transplant Recipients with Non-response to Previous Hepatitis B VaccinationIn: Scandinavian Journal of Immunology, Jg. 85, 2017, Nr. 1, S. 51 – 57DOI (Open Access)
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Immunosuppression with mTOR inhibitors prevents the development of donor-specific antibodies after liver transplantIn: Clinical Transplantation, Jg. 31, 2017, Nr. 6, S. e12974
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Impact of donor specific antibodies following liver transplantationIn: Transplant International, Jg. 30, 2017, Nr. Suppl. 4, S. 14 – 14
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Pretransplant serum Baff Levels are Associated with Pretransplant HLA - Immunization and renal Allograft SurvivalIn: Transplant International, Jg. 30, 2017, Nr. Suppl. 2, S. 101
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Abo incompability has an impact on t-cell flow cytometry crossmatch resultsIn: HLA: Immune Response Genetics (Human Leukocyte Antigens), Jg. 87, 2016, Nr. 4, S. 237
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Diagnostics and treatment of a severe humoral rejection after liver transplantation : donor-specific antibodies as a still underestimated cause of graft failureIn: Zeitschrift für Gastroenterologie, Jg. 54, 2016, Nr. 7, S. 647 – 652
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Functional distance between recipient and donor HLA-DPB1 determines nonpermissive mismatches in unrelated HCT : ErratumIn: Blood, Jg. 128, 2016, Nr. 23, S. 2744
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Functional distance between recipient and donor HLA-DPB1 determines nonpermissive mismatches in unrelated HCTIn: Blood, Jg. 128, 2016, Nr. 1, S. 120 – 129DOI (Open Access)
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The Functional Distance Between Mismatched HLA-DPB1 Increases Risks of Relapse and Mortality after Unrelated Donor Hematopoietic Cell Transplantation for AML, ALL and MDS : A Refinement of the T Cell Epitope Group Algorithm for Permissive MismatchesIn: Biology of Blood and Marrow Transplantation, Jg. 22, 2016, Nr. 3, Supplement, S. 420 – S.421
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Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection PressureIn: Hepatology, Jg. 62, 2015, Nr. 1, S. 47 – 56DOI (Open Access)
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Molecular signatures reveal a novel HLA-B*15-restricted CD8 T cell epitope on the large hepatitis delta antigenIn: Journal of Viral Hepatitis, Jg. 22, 2015, Nr. S2, Special Issue: 15th International Symposium on Viral Hepatitis and Liver Diseases (ISVHLD) held from June 26th to 28th, 2015, in Berlin, Germany, S. 109
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Targeting outside HLA polymorphisms for QPCR-based monitoring of hematopoietic chimerism from periphal blood or bone marrow after unrelated HSCT
European Federation for Immunogenetics Conference, April 26th–29th, 2015, Geneva, Switzerland,In: Tissue Antigens, Jg. 85, 2015, Nr. 5, S. 359 -
The Functional Distance Between Mismatched HLA-DPB1 Increases Risks of Relapse and Mortality after Unrelated Donor Hematopoietic Cell Transplantation for AML, ALL and MDS : A Refinement of the T Cell Epitope Group Algorithm for Permissive MismatchesIn: Blood, Jg. 126, 2015, Nr. 23, S. 4288
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Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cellsIn: Journal of Virology, Jg. 88, 2014, Nr. 19, S. 11080 – 11090
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KIR2DL3+NKG2A− natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugsIn: Journal of Hepatology, Jg. 61, 2014, Nr. 3, S. 475 – 481
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Pretransplant DSA But Not Complement Fixing HLA Antibodies Are Associated with Increased Risk for Antibody Mediated Rejection in Kidney TransplantationIn: Transplantation, Jg. 98, 2014, Nr. Suppl. 1, S. 679
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Pretransplant DSA But Not Complement Fixing HLA Antibodies Are Associated with Increased Risk for Antibody Mediated Rejection in Kidney TransplantationIn: American Journal of Transplantation, Jg. 14, 2014, Nr. Suppl. 3, S. 679
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Shift of HIV tropism in stem-cell transplantation with CCR5 Delta32 mutationIn: The New England Journal of Medicine, Jg. 371, 2014, Nr. 9, S. 880 – 882
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Characterization of mannose-binding lectin (MBL) variants by allele-specific sequencing of MBL2 and determination of serum MBL protein levelsIn: Tissue Antigens, Jg. 82, 2013, Nr. 6, S. 410 – 415
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Deleterious impact of HLA-DRB1 allele mismatch in sensitized recipients of kidney retransplantsIn: Transplantation, Jg. 95, 2013, Nr. 1, S. 137 – 141
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Glomerular endothelial microrona expression profiles in an in-vitro moedl of acute humoral rejectionIn: Transplant International, Jg. 26, 2013, Nr. Suppl. 1, S. 46 Abstract P104
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Pneumococcal antibodies in kidney transplant recipients are predictive of patient survivalIn: Scandinavian Journal of Immunology, Jg. 78, 2013, Nr. 6, S. 554 – 556
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Characterization of four new HLA alleles : HLA-B*15:01:18, HLA-B*44:110, HLA-C*04:01:22 and HLA-DQB 1*05:14In: Tissue Antigens, Jg. 79, 2012, Nr. 3, S. 209 – 210
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Pretransplant C1Q fixing HLA antibodies and humoral rejections in patients after living kidney transplantationIn: Tissue Antigens, Jg. 79, 2012, Nr. 6, S. 504
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A Non-Interventional Clinical Study on the Performance of NGStrack
38th EFI Conference; 14 – 17 May 2025; Prague, The Czech Republic,In: HLA: Immune Response Genetics (Human Leukocyte Antigens). Hoboken: Wiley-Blackwell - STM, Jg. 105, 2025, Nr. S1, P51(Open Access) -
Development of de Novo Anti-HLA-DSA in renaö transplant patients depends on CYP3A5 genotypeIn: Transplant International. Lausanne: Frontiers Media, Jg. 33, 2020, Nr. S2, Special Issue: Abstracts of the 29th Annual Meeting of the German Transplantation Society, Cologne, Germany, 15–17 October 2020, S. 10 – 11DOI (Open Access)
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Exploiting Cutting-Edge Technologies to Analyze Loss of HLA in a Global Multicentric Cohort of Post-Transplantation Relapses : Preliminary Results from the HLALOSS Collaborative Study
The 44th Annual Meeting of the European Society for Blood and Marrow Transplantation; Mar 18 - 21, 2018; Lisboa, Portugal,In: Bone Marrow Transplantation. London: Springer Nature, Jg. 53, 2018, Nr. Supplement, S. 22 – 23 -
Exploiting cutting-edge technologies to analyze loss of HLA in a global multicentric cohort of post-transplantation relapses : Preliminary results from the HLA Loss Collaborative StudyIn: HLA: Immune Response Genetics (Human Leukocyte Antigens). Hoboken: Wiley-Blackwell - STM, Jg. 91, 2018, Nr. 5, S. 324 – 325
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Incidence of HLA Loss in a Global Multicentric Cohort of Post-Transplantation Relapses: Results from the Hlaloss Collaborative Study
60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 132, 2018, Nr. Supplement 1: 60th ASH Annual Meeting Abstracts, S. 818 – 818DOI (Open Access) -
Investigation of HLA loss relapse after allogeneic stem cell transplantation in a global multicentric cohort (HLALOSS Consortium)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 237 – 238DOI (Open Access) -
Abo blood group incompatibility has an impact on t-cell flow cytometry crossmatch resultsIn: Transplant International. Lausanne: Frontiers Media, Jg. 29, 2016, Nr. Suppl. 3, Special Issue: Abstracts of the 25th Annual Meeting of the German Transplantation Society, Essen, Germany, 5–8 October 2016, S. 25
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Correlation of Mutations within HDV-Protein with HLA Backgrounds of Patients Leads to Identification of Novel CD8 T Cell EpitopesIn: Journal of Hepatology. Amsterdam; Copenhagen; Oxford: Elsevier, Jg. 64, 2016, Nr. 2, Suppl., S. S361
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Donor specific antibodies post liver transplant : Predictors and protectorsIn: Journal of Hepatology. Amsterdam; Copenhagen; Oxford: Elsevier, Jg. 64, 2016, Nr. 2, Suppl., S. S544
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From HLA-DPV 1 genetic distance to functional distance in hematopoietic stem cell transplantationIn: HLA: Immune Response Genetics (Human Leukocyte Antigens). Hoboken: Wiley-Blackwell - STM, Jg. 87, 2016, Nr. 4, S. 210 – 211
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Humoral and cellular responses to a single dose of fendrix in kidney transplant recipients with non-response to conventional Hepatitis B vaccinesIn: Transplant International. Lausanne: Frontiers Media, Jg. 29 Suppl. 3, 2016, S. 16 V107
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Increased pretransplant serum baff levels are associated with reduced renal allograft survivalIn: Transplant International. Lausanne: Frontiers Media, Jg. 29, 2016, Nr. Suppl. 3, Special Issue: Abstracts of the 25th Annual Meeting of the German Transplantation Society, Essen, Germany, 5–8 October 2016, S. 26
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KIR3DL1 in Combination with HLA-BW4-80T is Associated with Superior Functionality of NK Cells and Spontaneous Immune Control of HCV Infection in People who Inject DrugsIn: Journal of Hepatology. Amsterdam; Copenhagen; Oxford: Elsevier, Jg. 64, 2016, Nr. 2, Suppl., S. S515
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Predictors and protectors of donor specific antibodies after liver transplantationIn: Transplant International. Lausanne: Frontiers Media, Jg. 29, 2016, Nr. Suppl. 3, S. 22
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Predictors for the Development of Donor Specific Antibodies After Liver TransplantationIn: Transplantation. Philadelphia: Lippincott Williams & Wilkins, Jg. 100, 2016, Nr. Suppl. 5, S. 238
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A new approach to non-permissive HLA-DPB 1 mismatches in unrelated HSCT based on the functional distance between petient and donor
European Federation for Immunogenetics Conference, April 26th–29th, 2015, Geneva, Switzerland,In: Tissue Antigens. Oxford: Wiley-Blackwell, Jg. 85, 2015, Nr. 5, S. 314 – 315 -
Despite intensified immunosuppression flow cytometry crossmatch results are predictive of antibody-mediated rejection
24th Annual Meeting of the German Transplantation Society, 22–24 October 2015, Dresden, Germany,In: Transplant International. Lausanne: Frontiers Media, Jg. 28, 2015, Nr. S2, S. 44 -
Quantitative PCR is a sensitive and reliable tool for chimerism monitoring in peripheral blood and bone marrow after unrelated HCTIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 50, 2015, Nr. Suppl. 1, S. 448
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The combined impact of amino acid polymorphism at HLA-DPB1 on T cell alloreactivity defines a functional distance between patient and donor independently predictive of survival after 10/10 matched unrelated HSCT for AML and MDSIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 50, 2015, Nr. Suppl. 1, S. S359 – S360
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The combined impact of amino acid polymorphism at HLA-DPB1 on T cell alloreactivity defines a functional distance between patient and donor independently predictive of survival after 10/10 matched unrelated HSCT for AML, ALL and MDS
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,In: Oncology Research and Treatment. Basel: Karger, Jg. 38, 2015, Nr. Suppl. 5, S. 34 -
qPCR-based monitoring of hematopoietic chimerism after stem cell transplantation
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,In: Oncology Research and Treatment. Basel: Karger, Jg. 38, 2015, Nr. Suppl. 5, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie Basel, 9.-13. Oktober 2015: Abstracts, S. 258 -
Negative impact of HLA-DPB 1 t-cell epitope mismatches on survival after unrelated hematopoietic stem cell transplantation for AML in a german single center
28th EFI European Immunogenetics and Histocompatibility Conference Stockholm, Sweden, June 25th–28th, 2014,In: Tissue Antigens. Oxford: Wiley-Blackwell, Jg. 84, 2014, Nr. 1, S. 39 – 39 -
Pretransplant DSA but not complement fixing HLA antibodies are associated with increased risk for antibody mediated rejection in kidney transplantation
23rd Annual Meeting of the German Transplantation Society, Mannheim, Germany, 16–18 October 2014,In: Transplant International. Lausanne: Frontiers Media, Jg. 27, 2014, Nr. Suppl. 3, S. 3 -
Pretransplant dsa but not complement fixing HLA antibodies are associated with increaesed risk for antibody mediated rejection in kidney transplantation
28th EFI European Immunogenetics and Histocompatibility Conference Stockholm, Sweden, June 25th–28th, 2014,In: Tissue Antigens. Oxford: Wiley-Blackwell, Jg. 84, 2014, Nr. 1, S. 67 – 68 -
Shift of HIV-Tropism in a HIV-patient with large cell anaplastic T-cell-lymphoma undergoing allogeneic stem cell transplantation from a donor with homozygosity for the CCR5 delta32 mutation
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,In: Oncology Research and Treatment. Basel: Karger, Jg. 37, 2014, Nr. Suppl. 5, S. 38 -
Deleterious Impact of HLA-DRB1 Allele Mismatch in Sensitized Recipients of Kidney RetransplantsIn: Transplantation. Philadelphia: Lippincott Williams & Wilkins, Jg. 94, 2012, Nr. 10S, S. 194
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Pretransplant C1q Fixing Human Leukocyte Antigen Antibodies and Humoral Rejections in Patients after Living Kidney TransplantationIn: Transplantation. Philadelphia: Lippincott Williams & Wilkins, Jg. 94, 2012, Nr. 10S, S. 1070
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Chimerism Testing in Stem Cell TransplantationIn: Histocompatibility and Immunogenetics: A Guide for Practitioners / Oberle, Volker (Hrsg.). Weinheim: Wiley, 2025, S. 263 – 283
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Allele-specific single-nucleotide polymorphisms for NGS-based detection of HLA loss relapses after hematopoietic cell transplantation
Joint 35th European Immunogenetics and Histocompatibility Conference; May 17–20, 2022; Amsterdam, the Netherlands,In: HLA: Immune Response Genetics (Human Leukocyte Antigens). Hoboken: Wiley-Blackwell - STM, Jg. 99, 2022, Nr. 5, SI, S. 487