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Assistenzarzt/-ärztin, Zentrum für Kinder- und Jugendmedizin
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SoSe 2025
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Cerebrospinal Fluid-Derived Small Extracellular Vesicles May Better Reflect Medulloblastoma Proteomes than Those from Blood PlasmaIn: International Journal of Molecular Sciences (IJMS), Jg. 26, 2025, Nr. 19, 9279DOI (Open Access)
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Corrigendum to “European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescence”In: EJC Paediatric Oncology, Jg. 6, 2025, 100305DOI (Open Access)
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Distinct relapse pattern across molecular ependymoma typesIn: Neuro-Oncology, Jg. 27, 2025, Nr. 1, S. 267 – 276
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European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescenceIn: EJC Paediatric Oncology, Jg. 5, 2025, 100227DOI (Open Access)
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Malignant Rhabdoid Tumors of Cranial Nerves : A Clinically Distinct Group With Characteristic Neuroradiological, Histopathological, and Molecular FeaturesIn: Pediatric Blood and Cancer, Jg. 72, 2025, Nr. 8, e31823DOI (Open Access)
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Palliativversorgung von Menschen mit kulturell und sprachlich diversem HintergrundIn: Monatsschrift Kinderheilkunde, Jg. 173, 2025, Nr. 10, S. 837 – 841DOI (Open Access)
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Recurrence patterns in pediatric intracranial ependymal neoplasm : A systematic imaging work-upIn: Neuroradiology, Jg. 67, 2025, Nr. 3, S. 767 – 781DOI (Open Access)
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Salvage therapies for first relapse of SHH medulloblastoma in early childhoodIn: Neuro-Oncology, Jg. 27, 2025, Nr. 8, S. 2158 – 2169DOI (Open Access)
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High Parathyroid Hormone Rather than Low Vitamin D Is Associated with Reduced Event-Free Survival in Childhood CancerIn: Cancer Epidemiology, Biomarkers & Prevention, Jg. 33, 2024, Nr. 11, S. 1414 – 1422DOI (Open Access)
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Outcome After Modern Proton Beam Therapy in Childhood Craniopharyngioma : Results of the Prospective Registry Study KiProRegIn: International Journal of Radiation Oncology, Biology, Physics, Jg. 120, 2024, Nr. 1, S. 137 – 148DOI (Open Access)
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Radiotherapy for Recurrent Medulloblastoma in Children and Adolescents : Survival after Re-Irradiation and First-Time IrradiationIn: Cancers, Jg. 16, 2024, Nr. 11, 1955DOI, Online Volltext (Open Access)
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Functional outcome after initial and multiple intracerebral hemorrhages in children with cerebral cavernous malformationsIn: European Journal of Neurology, Jg. 30, 2023, Nr. 5, S. 1364 – 1370DOI (Open Access)
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Functional outcome after pediatric cerebral cavernous malformation surgeryIn: Scientific Reports, Jg. 13, 2023, Nr. 1, 2286DOI, Online Volltext (Open Access)
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Giant Cavernous Malformation Mimicking an Infiltrative Intracranial Neoplasm in Children–Case Report and Systematic Review of the LiteratureIn: World Neurosurgery, Jg. 174, 2023, S. 30 – 41
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Outcome after conservative or surgical treatment for new-onset epilepsy in children with cerebral cavernous malformationIn: Seizure, Jg. 111, 2023, S. 23 – 29
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Surface Chemistry and Specific Surface Area Rule the Efficiency of Gold Nanoparticle Sensitizers in Proton TherapyIn: Chemistry - A European Journal, Jg. 29, 2023, Nr. 50, e202301260DOI (Open Access)
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Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORMIn: npj Precision Oncology, Jg. 6, 2022, Nr. 1, 94DOI (Open Access)
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Evaluation of dose, volume, and outcome in children with localized, intracranial ependymoma treated with proton therapy within the prospective KiProReg StudyIn: Neuro-Oncology, Jg. 24, 2022, Nr. 7, S. 1193 – 1202DOI (Open Access)
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Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry : A Unique and Challenging PopulationIn: Cancers, Jg. 14, 2022, Nr. 9, 2185DOI (Open Access)
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Local and Systemic Therapy of Recurrent Medulloblastomas in Children and Adolescents : Results of the P-HIT-REZ 2005 StudyIn: Cancers, Jg. 14, 2022, Nr. 3, 471DOI (Open Access)
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Long-term outcome after management of pilocytic astrocytoma in the posterior fossa in a pediatric populationIn: IBRO Neuroscience Reports, Jg. 13, 2022, S. 388 – 392DOI (Open Access)
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Multimodal Treatment of Nasopharyngeal Carcinoma in Children, Adolescents and Young Adults-Extended Follow-Up of the NPC-2003-GPOH Study Cohort and Patients of the Interim CohortIn: Cancers, Jg. 14, 2022, Nr. 5, 1261DOI (Open Access)
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Natural Course of Cerebral Cavernous Malformations in Children : A Five-Year Follow-Up StudyIn: Stroke, Jg. 53, 2022, Nr. 3, S. 817 – 824DOI (Open Access)
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Prevalence of osteopathologies in a single center cohort of survivors of childhood primary brain tumorIn: Frontiers in Pediatrics, Jg. 10, 2022, 913343DOI, Online Volltext (Open Access)
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Proton Beam Therapy for Pediatric Tumors of the Central Nervous System : Experiences of Clinical Outcome and Feasibility from the KiProReg StudyIn: Cancers, Jg. 14, 2022, Nr. 23, 5863DOI, Online Volltext (Open Access)
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Relapsed medulloblastoma in pre-irradiated patients : Current practice for diagnostics and treatmentIn: Cancers, Jg. 14, 2022, Nr. 1, 126DOI (Open Access)
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Biallelic PI4KA variants cause neurological, intestinal and immunological diseaseIn: Brain: A Journal of Neurology, Jg. 144, 2021, Nr. 12, S. 3597 – 3610DOI (Open Access)
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Clinical and genetic risk factors define two risk groups of extracranial malignant rhabdoid tumours (eMRT/RTK)In: European Journal of Cancer (EJC), Jg. 142, 2021, S. 112 – 122
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Feasibility of Proton Beam Therapy for Infants with Brain Tumours : Experiences from the Prospective KiProReg Registry StudyIn: Clinical Oncology, Jg. 33, 2021, Nr. 7, S. e295 – e304
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Local and systemic therapy of recurrent ependymoma in children and adolescents : Short- and long-term results of the E-HIT-REZ 2005 studyIn: Neuro-Oncology, Jg. 23, 2021, Nr. 6, S. 1012 – 1023DOI, Online Volltext (Open Access)
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Proton Beam Therapy for Children With Neuroblastoma : Experiences From the Prospective KiProReg RegistryIn: Frontiers in Oncology, Jg. 10, 2021, S. 617506DOI, Online Volltext (Open Access)
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Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/BIn: Nature Communications, Jg. 12, 2021, Nr. 1, 5530DOI (Open Access)
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Systemic chemotherapy of pediatric recurrent ependymomas : results from the German HIT-REZ studiesIn: Journal of Neuro-Oncology, Jg. 155, 2021, Nr. 2, S. 193 – 202DOI (Open Access)
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The Pediatric Precision Oncology INFORM Registry : Clinical Outcome and Benefit for Patients with Very High-Evidence TargetsIn: Cancer Discovery, Jg. 11, 2021, Nr. 11, S. 2764 – 2779DOI (Open Access)
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Age and DNA methylation subgroup as potential independent risk factors for treatment stratification in children with atypical teratoid/rhabdoid tumorsIn: Neuro-Oncology, Jg. 22, 2020, Nr. 7, S. 1006 – 1017DOI, Online Volltext (Open Access)
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Desmoplastic myxoid tumor, SMARCB1-mutant : clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adultsIn: Acta Neuropathologica, Jg. 139, 2020, Nr. 2, S. 277 – 286
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In reply to Gultekin and YildizIn: International Journal of Radiation Oncology, Biology, Physics, Jg. 105, 2019, Nr. 5, S. 1164 – 1165
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Newly Diagnosed Metastatic Intracranial Ependymoma in Children : Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT SeriesIn: The Oncologist, Jg. 24, 2019, Nr. 7DOI (Open Access)
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Outcome and Patterns of Relapse in Childhood Parameningeal Rhabdomyosarcoma Treated With Proton Beam TherapyIn: International Journal of Radiation Oncology, Biology, Physics, Jg. 105, 2019, Nr. 5, S. 1043 – 1054
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DNA methylation-based classification of central nervous system tumoursIn: Nature, Jg. 555, 2018, Nr. 7697, S. 469 – 474DOI (Open Access)
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Irradiation of the craniospinal Axis at the West German Proton Therapy Center Essen (WPE)In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics, Jg. 194, 2018, Nr. Suppl. 1, S. S30 – S31DOI (Open Access)
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Proton Therapy of Clivuschordomas at the West German Proton Therapy Center Essen (WPE) - First Results of a prospective Study on the Compatibility within the Framework of ProReg and KiProRegIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics, Jg. 194, 2018, Nr. Suppl. 1, S. 101DOI (Open Access)
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Role of irradiation in relapsed medulloblastoma : a report of the German Medulloblastoma Relapse StudiesIn: Neuro-Oncology, Jg. 20, 2018, Nr. Suppl_2, Abstracts from the 18th International Symposium on Pediatric Neuro-Oncology (ISPNO 2018), S. i127DOI, Online Volltext (Open Access)
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Feasibility and Toxicity of Simultaneously Administrated Chemotherapy and Proton Therapy in Children and Adolescents
49th Congress of the International Society of Paediatric Oncology (SIOP), October 12–15, 2017, Washington, DC, USA,In: Pediatric Blood and Cancer, Jg. 64, 2017, Nr. Suppl. 3, S. S339 -
Successful multimodal treatment of a gigantic choroid plexus carcinoma (CPC) in an 8-year-old girlIn: Child's Nervous System, Jg. 33, 2017, Nr. 11, S. 1875 – 1877
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Divergent clonal selection dominates medulloblastoma at recurrenceIn: Nature, Jg. 529, 2016, Nr. 7586, S. 351 – 357DOI, Online Volltext (Open Access)
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Evidence of H3 K27M mutations in posterior fossa ependymomasIn: Acta Neuropathologica, Jg. 132, 2016, Nr. 4, S. 635 – 637
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Intraventricular etoposide safety and toxicity profile in children and young adults with refractory or recurrent malignant brain tumorsIn: Journal of Neuro-Oncology, Jg. 128, 2016, Nr. 3, S. 463 – 471
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Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot studyIn: European Journal of Cancer (EJC), Jg. 65, 2016, S. 91 – 101
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Relapse patterns and outcome after relapse in standard risk medulloblastoma : a report from the HIT-SIOP-PNET4 studyIn: Journal of Neuro-Oncology, Jg. 129, 2016, Nr. 3, S. 515 – 524DOI (Open Access)
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Intraventricular therapy with etoposide in recurrent medulloblastomas, pineoblastomas, CNS-PNETS ans ependymomas - final results of a PHASE II STUDYIn: Neuro-Oncology, Jg. 16, 2014, Nr. Suppl. 1, S. 10
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Postponed is not canceled : Role of craniospinal radiation therapy in the management of recurrent infant medulloblastoma ; an experience from the HIT-REZ 1997 \& 2005 studiesIn: International Journal of Radiation Oncology, Biology, Physics, Jg. 88, 2014, Nr. 5, S. 1019 – 1024
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Growth hormone deficiency in relation to radiation dose to the hypothalamus and pituitary gland in children treated with proton beam therapyIn: Radiotherapy and Oncology (The Green Journal). Amsterdam: Elsevier, Jg. 206, 2025, Nr. Supplement 1, S. S1624 – S1626
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Proton Radiation in Children with Thoracic Ewing Sarcoma : Results of the Prospective KiProReg RegistryIn: International Journal of Radiation Oncology, Biology, Physics. New York: Elsevier, Jg. 121, 2025, Nr. 3, S. e10
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Proton therapy in patients with thoracic Ewing sarcomas : Early Result from the Prospective Registry Studies KiProReg and ProRegIn: Radiotherapy and Oncology (The Green Journal). Amsterdam: Elsevier, Jg. 206, 2025, Nr. Supplement 1, S. S1688 – S1689
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Distinct Relapse Pettern across Molecular Ependymoma TypesIn: Neuro-Oncology. Oxford: Oxford University Press, Jg. 26, 2024, Nr. Supplement_4DOI (Open Access)
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Elucidating the clinical spectrum and expanding genotype-phenotype associations in PI4KA-related disorder
57th European Society of Human Genetics (ESHG) Conference, June 1-4, 2024, Berlin, Germany,In: European Journal of Human Genetics. Basingstoke: Nature Publishing Group, Jg. 32, 2024, Nr. Supplement 2, S. 882 – 883Online Volltext (Open Access) -
Development of a functional Platform for Real-Time personalized Drug Sensitivity profiling of Patient-Derived 3D Fresh Tumor Tissue Cultures in the Pediatric Precision Oncology Program Inform
7th Biennial Pediatric Neuro-Oncology Research Conference ; June 22-24, 2023, Washington, DC, USA,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 25, 2023, Nr. Supplement 1, S. i74 – i75DOI (Open Access) -
Hyperparathyroidism is associated with inferior event free survival in lymphatic childhood malignancies in a single center retrospective analysisIn: Hormone Research in Paediatrics. Basel: Karger, Jg. 96, 2023, Nr. Suppl. 4, S. 134
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ATRT-05. Infants and newborns with atypical teratoid/rhabdoid tumors (ATRT) and extracranial malignant rhabdoid tumors : a unique and challenging population
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Suppl 1: Abstracts from the 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i2 – i3DOI (Open Access) -
ATRT-14. Malignant rhabdoid tumors of cranial nerves – ATRT or extracranial rhabdoid tumor?
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1: Abstracts from the 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i5 – i6DOI (Open Access) -
MEDB-17. Re-irradiation for recurrent medulloblastoma in a matched cohort: Advantageous especially in patients without resection
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1: 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i108DOI (Open Access) -
MEDB-38. Significance of CSF cytology and neurologic deterioration in relapsed medulloblastomas in the German HIT-REZ-97/-2005 Studies and the HIT-REZ-Register
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1: Abstracts from the 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i113 – i114DOI (Open Access) -
NFB-13. Rhabdoid Tumor Predisposition Syndrome (RTPS) – Finding Evidence by systematic Analyses
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1: Abstracts from the 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i130 – i131DOI (Open Access) -
Proton Beam Therapy in Children with Atypical Teratoid Rhabdoid Tumours - : Prospective Single-Institution Analyses of Feasibilty and Outcome
54th Congress of the International Society of Paediatric Oncology (SIOP), September 28 – October 1, 2022,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 69, 2022, Nr. S5, S. S30DOI (Open Access) -
Protonentherapie für Kraniopharyngeome : Ergebnisse der prospektiven Registerstudien ProReg und KiProReg
28. Kongress der Deutschen Gesellschaft für Radioonkologie ; DEGRO 2022 ; 26. bis 28.05.2022, Stuttgart, Germany,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 198, 2022, Nr. Supplement 1, S. S26DOI (Open Access) -
RONC-16. Proton therapy for patients with embryonal tumor with multilayered rosettes in early childhood – results of the prospective KiProReg Study
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1: Abstracts from the 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i180 – i180DOI (Open Access) -
RONC-17. Feasibility of proton therapy with and without simultaneous chemotherapy in CNS malignancies of children and adolescents
20th International Symposium on Pediatric Neuro-Oncology, 2022,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1, S. i180DOI (Open Access) -
Tolerance of brain and brainstem dose in children with proton beam re-irradation in relapsed tumours of the central nervous system
54th Congress of the International Society of Paediatric Oncology (SIOP), September 28 – October 1, 2022,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 69, 2022, Nr. S5, S. S30DOI (Open Access) -
Proton Therapy in the Treatment of Non Metastatic Intracranial Germinoma : Early Result
53rd Congress of the international Society of Paediatric Oncology (SIOP), Virtual Congress, October 21-24, 2021,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 68, 2021, Nr. S5, S. S45 – S46DOI (Open Access) -
Re-Irradiation with Proton Therapy of Tumors of the central Nervous System : Results from the prospective Therapy Studies ProReg and KiProRegIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 197, 2021, Nr. Suppl. 1, S. 73 – S74
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Zfta Fusion-Positive Ependymomas Show a Dismal Outcome at Relapse
53rd Congress of the international Society of Paediatric Oncology (SIOP), Virtual Congress, October 21-24, 2021,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 68, 2021, Nr. S5, S. S115 – S116DOI (Open Access) -
Chemotherapy of recurrent ependymoma : Long term response only in few cases
19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), 13.-16.12.2020, Karuizawa, Japan,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 22, 2020, Nr. Supplement_3: Abstracts from the 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), S. iii309DOI (Open Access) -
Chromosome 1q Gain in Recurrent PF-A Ependymoma Predicts Worse Outcome after First Relapse
52th Congress of the International Society of Paediatric Oncology (SIOP) Virtual Congress, 14.-17.10.2020, Ottawa, Canada,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 67, 2020, Nr. S4, S. S302 – S303DOI (Open Access) -
Peds : Pediatric ependymoma discovery study
19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), 13.-16.12.2020, Karuizawa, Japan,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 22, 2020, Nr. Supplement_3: Abstracts from the 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), S. iii317DOI (Open Access) -
Early ototoxicity in children after craniospinal irradiation using pencil beam proton therapy
Congress of the Pediatric Radiation Oncology Society (PROS) ; June 19-22, 2019, Bangkok, Thailand,In: International Journal of Radiation Oncology, Biology, Physics. New York: Elsevier, Jg. 105, 2019, Nr. 4, S. 912 -
Clinical and Genetic Risk Factors Define Two Risk Groups of Extracranial Rhabdoid Tumors : A Plea for High Risk Tailored Therapies
50th Congress of the International Society of Paediatric Oncology (SIOP), November 16–19, 2018, Kyoto, Japan,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 65, 2018, Nr. Suppl. 2, S. S57DOI (Open Access) -
Congenital rhabdoid tumors as a major clinical challenge - a collaborative european effortIn: Neuro-Oncology. Oxford: Oxford University Press, Jg. 20, 2018, Nr. Suppl. 2, S. 30 – 31DOI (Open Access)
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Proton Beam Therapy for Ependymomas of Childhood; Early Data From the Prospective KiProReg Registry
PROS Congress ; 22 - 25 June 2017, New York, USA,In: International Journal of Radiation Oncology, Biology, Physics. New York: Elsevier, Jg. 101, 2018, Nr. 4, S. 1009 -
Protonentherapie bei orbitalen Rhabdomyosarkomen am Westdeutschen Protonentherapiezentrum Essen (WPE)
24. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 21. Juni 2018 - 24. Juni 2018, Leipzig,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 194, 2018, Nr. 1 Supplement, Abstracts DEGRO 2018, Seite S81DOI (Open Access) -
Results of Pharmacokinetic analysis of intraventricular Etoposide in a Phase II Study of Recurrent Medulloblastoma, CNS-PNET and Ependymoma
47th Congress of the International Society of Paediatric Oncology (SIOP) Cape Town, South Africa October 8–11, 2015,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 62, 2015, Nr. S 4, Abstracts From the 47th Congress of the International Society of Paediatric Oncology (SIOP) Cape Town, South Africa October 8–11, 2015, S. S284 -
Role of Craniospinal Radiation Therapy in the Management of Recurrent Medulloblastoma : Experiences From the Prospective German HIT-REZ 1997 and 2005 Studies
55th Annual Meeting of the American Society for Radiation Oncology ; 22-25 September 2013, Atlanta, GA, USA,In: International Journal of Radiation Oncology, Biology, Physics. New York: Elsevier, Jg. 87, 2013, Nr. 2, Supplement, S. S37 – S38