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Universitätsstr. 1-5
45141 Essen
45141 Essen
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S03 S01 A35
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Termine im Sekretariat erhältlich
Funktionen
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Vorsitzender, Prüfungsausschuss B.Sc./M.Sc.-Studiengänge Biologie mit Lehramtsoption
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Universitätsprofessor/in, Strukturelle und Medizinische Biochemie
Aktuelle Veranstaltungen
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2022 SS
- Mentoringgespräch
- Vertiefungsarbeit LA alte LPO und Ba LA
- Bausteine des Lebens: Einführung in die Biochemie für Hauptstudium LA Chemie, Biotechnik und BSc Chemie Vorlesung/Klausur
- Struktur und Funktion (LA Ba) - Anmeldung mit mehreren Prioritäten
- ZJA40148 + ZJA71009 + ZJA71017 Struktur und Funktion (Stiftklausur)
- Physiologie für aquatische Biologen
- ZIA95306 EnvITox-MA-3.1 Biochemistry: structure and function of biomolecules
- ZJA40120 Physik (Stiftklausur)
- ZIA71044 - Klausur Struktur und Funktion
- ZIA71054; ZIA71055; ZIA40166 - Klausur Biochemie
Vergangene Veranstaltungen (max. 10)
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2021 WS
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- ZIA71054/71055/40166 Klausur Biochemie (Bausteine des Lebens: Einführung in die Biochemie); Prof. P. Bayer
- Allgemeine Methoden Praktikum (Bachelor Bio); Priorität für G1 oder G2
- Allgemeine Methoden (Bachelor Bio)
- Vertiefungsarbeit LA alte LPO und Ba LA
- Physik für Biologen (Bio B.Sc. und Aquatische Bio B.Sc., Molekularbiologie)
- MedBio Lab Rotation
- Struktur und Funktion der Zelle (LA Ba)
- Biochemistry: Structure and function of biomolecules
- Mentoringgespräch
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Binding Methylarginines and Methyllysines as Free Amino Acids : A Comparative Study of Multiple Host ClassesIn: ChemBioChem Jg. 23 (2022) Nr. 2,
ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/ (Open Access) -
Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)In: Inorganic Chemistry Jg. 61 (2022) Nr. 12, S. 5133 - 5147
ISSN: 1520-510X; 0020-1669Online Volltext: dx.doi.org/ -
Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 21, S. 5645 - 5659
ISSN: 1520-5207; 1089-5647Online Volltext: dx.doi.org/ -
New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 1, S. 115 - 127
ISSN: 1520-5207; 1520-6106; 1089-5647Online Volltext: dx.doi.org/ -
Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein TargetingIn: ACS Applied Bio Materials Jg. 4 (2021) Nr. 1, S. 945 - 965
ISSN: 2576-6422Online Volltext: dx.doi.org/ (Open Access) -
Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1505
ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access) -
Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRafIn: ChemBioChem Jg. 22 (2021) Nr. 8, S. 1456 - 1463
ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/ (Open Access) -
Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeastIn: The EMBO Journal Jg. 39 (2020) Nr. 14, S. e102938
ISSN: 1460-2075; 0261-4189Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition Jg. 59 (2020) Nr. 14, S. 5567 - 5571
ISSN: 1521-3773; 1433-7851; 0570-0833Online Volltext: dx.doi.org/ (Open Access) -
NMR Spectroscopy of supramolecular chemistry on protein surfacesIn: Beilstein Journal of Organic Chemistry Jg. 16 (2020) S. 2505 - 2522
ISSN: 1860-5397; 2195-951XOnline Volltext: dx.doi.org/ (Open Access) -
Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerizationIn: Biological Chemistry Jg. 401 (2020) Nr. 8, S. 955 - 968
ISSN: 1437-4315; 1431-6730Online Volltext: dx.doi.org/ (Open Access) -
The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent mannerIn: Nanoscale Jg. 12 (2020) Nr. 37, S. 19093 - 19103
ISSN: 2040-3372; 2040-3364Online Volltext: dx.doi.org/ -
Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allosteryIn: Biomolecular NMR Assignments Jg. 13 (2019) Nr. 1, S. 85 - 89
ISSN: 1874-270X; 1874-2718Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopyIn: Langmuir Jg. 35 (2019) Nr. 22, S. 7191 - 7204
ISSN: 0743-7463; 1520-5827Online Volltext: dx.doi.org/ -
Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein InteractionsIn: ChemBioChem Jg. 20 (2019) Nr. 23, S. 2921 - 2926
ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/ -
Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)In: Langmuir Jg. 35 (2019) Nr. 3, S. 767 - 778
ISSN: 0743-7463; 1520-5827Online Volltext: dx.doi.org/ -
Structural Analysis of the 42 kDa Parvulin of Trypanosoma bruceiIn: Biomolecules Jg. 9 (2019) Nr. 3,
ISSN: 2218-273XOnline Volltext: dx.doi.org/ Online Volltext (Open Access) -
Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPaseIn: Biomolecules Jg. 9 (2019) Nr. 12,
ISSN: 2218-273XOnline Volltext: dx.doi.org/ Online Volltext (Open Access) -
Cell entry of a host-targeting protein of oomycetes requires gp96In: Nature Communications Jg. 9 (2018) Nr. 1, S. 2347
ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access) -
Structure and function of the human parvulins Pin1 and Par14/17In: Biological Chemistry Jg. 399 (2018) Nr. 2, S. 101 - 125
ISSN: 1437-4315; 1431-6730Online Volltext: dx.doi.org/ (Open Access) -
The RxLR motif of the host targeting effector AVR3a of phytophthora infestans is cleaved before secretionIn: The Plant Cell Jg. 29 (2017) Nr. 6, S. 1184 - 1195
ISSN: 1532-298X; 1040-4651Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Determinants of tyrosylprotein sulfation coding and substrate specificity of tyrosylprotein sulfotransferases in metazoansIn: Chemico-Biological Interactions Jg. 259 (2016) Nr. Part A, S. 17 - 22
ISSN: 0009-2797; 1872-7786Online Volltext: dx.doi.org/ -
Molecular tweezers target a protein-protein interface and thereby modulate complex formationIn: Chemical Communications: ChemComm Jg. 52 (2016) Nr. 98, S. 14141 - 14144
ISSN: 1364-548X; 0009-241X; 0022-4936; 1359-7345Online Volltext: dx.doi.org/ (Open Access) -
NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomeraseIn: BMC Biology (incorporating Journal of Biology) Jg. 14 (2016) Nr. 1, S. 53
ISSN: 1741-7007Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1In: PLoS ONE Jg. 11 (2016) Nr. 3, S. e0151431
ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Heterodimers of Tyrosylprotein Sulfotransferases Suggest Existence of a Higher Organization Level of Transferases in the Membrane of the trans-Golgi ApparatusIn: Journal of Molecular Biology (JMB) Jg. 427 (2015) Nr. Issue 6, Part B, S. 1404 - 1412
ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/ -
Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivoIn: BMC Biochemistry Jg. 16 (2015) Nr. 1,
ISSN: 1471-2091Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Structural model of the bilitranslocase transmembrane domain supported by NMR and FRET dataIn: PLoS ONE Jg. 10 (2015) Nr. 8, S. e0135455
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
The N-terminal region of the ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1) modulates interdomain communication within the valosin-containing protein p97In: The Journal of Biological Chemistry (JBC) Jg. 290 (2015) Nr. 49, S. 29414 - 29427
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ (Open Access) -
Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem Jg. 15 (2014) Nr. 15, S. 2233 - 2237
ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/ -
Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE Jg. 8 (2013) Nr. 6, S. e65346
ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Identification and characterization of peptides that bind the PPIase domain of Parvulin17In: Journal of Peptide Science Jg. 19 (2013) Nr. 6, S. 362 - 369
ISSN: 1099-1387; 1075-2617Online Volltext: dx.doi.org/ -
Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Jg. 21 (2013) Nr. 10, S. 1769 - 1777
ISSN: 1878-4186Online Volltext: dx.doi.org/ (Open Access) -
Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasmIn: PLoS ONE Jg. 7 (2012) Nr. 1, S. e29559
ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate-dependent mannerIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 109 (2012) Nr. 6, S. 2096 - 2101
ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ -
Structure of the corrinoid : coenzyme M methyltransferase MtaA from Methanosarcina mazeiIn: Acta Crystallographica Section D: Biological Crystallography Jg. 68 (2012) Nr. 11, S. 1549 - 1557
ISSN: 0907-4449; 1399-0047Online Volltext: dx.doi.org/ -
A potential transcriptional regulator is out-of-frame translated from the metallothionein 2A messenger RNAIn: Analytical Biochemistry Jg. 409 (2011) Nr. 1, S. 159 - 161
ISSN: 0003-2697; 1096-0309Online Volltext: dx.doi.org/ -
Crystallographic Proof for an Extended Hydrogen Bonding Network in Small Prolyl IsomerasesIn: Journal of the American Chemical Society: JACS Jg. 133 (2011) Nr. 50, S. 20096 - 20099
ISSN: 0002-7863; 1520-5126Online Volltext: dx.doi.org/ Online Volltext -
Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Jg. 7 (2011) S. 135 - 148
ISSN: 1176-9343Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl IsomerasesIn: The Journal of Biological Chemistry (JBC) Jg. 286 (2011) S. 6554 - 6565
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ (Open Access) -
The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domainsIn: Biological Chemistry Jg. 390 (2009) Nr. 5-6, S. 417 - 426
ISSN: 1437-4315Online Volltext: dx.doi.org/ -
Wie Proteine sich erkennen ... : ... und man ihnen dabei zusehen kann!In: Unikate: Berichte aus Forschung und Lehre (2009) Nr. 36: Naturwissenschaften/Medizin : Kernmagnetische Resonanz, S. 28 - 35
ISSN: 0944-6060; 1869-3881; 0941-746XOnline Volltext: dx.doi.org/ Online Volltext (Open Access) -
Small family with key contacts : par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical researchIn: Perspectives in Medicinal Chemistry Jg. 2 (2008) S. 11 - 20
ISSN: 1177-391XOnline Volltext: dx.doi.org/ (Open Access) -
15N magnetic relaxation study of backbone dynamics of the ribosomeassociated cold shock response protein Yfia of Escherichia coliIn: Acta Biochimica Polonica Jg. 54 (2007) Nr. 4, S. 769 - 775
ISSN: 1734-154X; 0001-527X(Open Access) -
The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae.In: BMC Biology (incorporating Journal of Biology) Jg. 5 (2007) S. 37
ISSN: 1741-7007Online Volltext: dx.doi.org/ -
Characterization of novel elongated Parvulin isoforms that are ubiquitously expressed in human tissues and originate from alternative transcription initiation.In: BMC Molecular Biology Jg. 7 (2006) S. 9
ISSN: 1471-2199 -
GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.In: Structure Jg. 14 (2006) S. 881 - 888
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Human TPST1 Transmembrane Domain Triggers Enzyme Dimerisation and Localisation to the Golgi CompartmentIn: Journal of Molecular Biology (JMB) Jg. 361 (2006) Nr. 3, S. 436 - 449
ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/ -
Isotopic labelling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.In: Protein Expression & Purification Jg. 48 (2006) S. 167 - 172
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Specification of SUMO1- and SUMO2-interacting motifsIn: The Journal of Biological Chemistry (JBC) Jg. 281 (2006) Nr. 23, S. 16117 - 16127
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ (Open Access) -
Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell lineIn: Chemical Communications: ChemComm Jg. 4 (2005) S. 516 - 518
ISSN: 1364-548X; 0009-241X; 0022-4936; 1359-7345Online Volltext: dx.doi.org/ -
The crystal structure of human PAPS synthetase 1 reveals asymmetry in substrate bindingIn: Journal of Molecular Biology (JMB) Jg. 347 (2005) Nr. 3, S. 623 - 635
ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/ -
Expression, purification and crystallization of human 3′- phosphoadenosine-5′-phosphosulfate synthetase 1In: Acta Crystallographica Section D: Structural Biology Jg. 60 (2004) Nr. 2, S. 350 - 352
ISSN: 0907-4449Online Volltext: dx.doi.org/ -
Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescensIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 101 (2004) Nr. 47, S. 16431 - 16436
ISSN: 0027-8424Online Volltext: dx.doi.org/ (Open Access) -
Die Vorliebe für Physik und die StrukturbiologieIn: Nachrichten aus der Chemie Jg. 51 (2003) Nr. 9, S. 917 - 917
ISSN: 1439-9598Online Volltext: dx.doi.org/ -
Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14In: Journal of Molecular Biology (JMB) Jg. 330 (2003) Nr. 5, S. 955 - 966
ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/ -
Structural analysis of the mitotic regulator hPin1 in solution : insights into domain architecture and substrate bindingIn: The Journal of Biological Chemistry (JBC) Jg. 278 (2003) Nr. 28, S. 26183 - 26193
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ (Open Access) -
Induction of tyrosylprotein sulfotransferase isoform shift in human endothelial cellsIn: Circulation Jg. 106 (2002) Nr. Suppl. 2, S. 287
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Letter to the Editor: ¹H, ¹³C and ¹⁵N resonance assignments of the ribosome-associated cold shock response protein Yfia of Escherichia coliIn: Journal of Biomolecular NMR Jg. 23 (2002) Nr. 4, S. 335 - 336
ISSN: 0925-2738Online Volltext: dx.doi.org/ -
Shear stress mediates tyrosylprotein sulfotransferase isoform shift in human endothelial cellsIn: Biochemical and Biophysical Research Communications Jg. 294 (2002) Nr. 3, S. 541 - 546
ISSN: 0006-291XOnline Volltext: dx.doi.org/ -
Solution structure of the ribosome-associated cold shock response protein Yfia of Escherichia coliIn: Biochemical and Biophysical Research Communications Jg. 299 (2002) Nr. 5, S. 710 - 714
ISSN: 0006-291XOnline Volltext: dx.doi.org/ -
Structural attributes in the conjugation of Ubiquitin, RUB and SUMO to protein substrates.In: Frontiers in Bioscience Jg. 7 (2002) S. 148 - 162
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The N-terminal basic domain of human parvulin h Par14 is responsible for the entry to the nucleus and high-affinity DNA-bindingIn: Journal of Molecular Biology (JMB) Jg. 321 (2002) Nr. 2, S. 235 - 247
ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/ -
Increased backbone flexibility in threonineIn: Biochemistry Jg. 40 (2001) Nr. 27, S. 7957 - 7963
ISSN: 1520-4995; 0006-2960Online Volltext: dx.doi.org/ -
Structure prediction of protein complexes by an NMR-based protein docking algorithmIn: Journal of Biomolecular NMR Jg. 20 (2001) Nr. 1, S. 15 - 21
ISSN: 0925-2738Online Volltext: dx.doi.org/ -
NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the proteinIn: Journal of Molecular Biology (JMB) Jg. 301 (2000) Nr. 4, S. 1003 - 1017
ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/ -
Nuclear magnetic resonance methods to study RNA-protein complexesIn: Methods in Enzymology Jg. 317: RNA - Ligand Interactions, Part A (2000) S. 198 - 220
ISSN: 1557-7988; 0076-6879Online Volltext: dx.doi.org/ -
Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37)In: Biochemical and Biophysical Research Communications Jg. 267 (2000) Nr. 1, S. 213 - 220
ISSN: 0006-291XOnline Volltext: dx.doi.org/ -
Book Review: Protein Structure: Determination, Analysis, and Applications for Drug Discovery. Edited by Daniel I. ChasmanIn: ChemBioChem Jg. 5 (2004) Nr. 4, S. 547 - 548
ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/ -
A molecular handshakeIn: Trends in Biochemical Sciences Jg. 27 (2002) Nr. 10, S. 502 - 503
ISSN: 1362-4326; 0968-0004Online Volltext: dx.doi.org/ -
ATP, a trigger for pain-signalingIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 1, S. 12
ISSN: 1362-4326; 0968-0004Online Volltext: dx.doi.org/ -
Delta: a mitogenic regulator of human hematopoesisIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 5, S. 281
ISSN: 1362-4326; 0968-0004Online Volltext: dx.doi.org/ -
Living in the cytosolIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 12, S. 702
ISSN: 1362-4326; 0968-0004Online Volltext: dx.doi.org/ -
TonB – a mediator of iron uptake in bacteriaIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 8, S. 472
ISSN: 1362-4326; 0968-0004Online Volltext: dx.doi.org/ -
A NMR-spectra based scoring function for protein docking.In: The Fifth Annual International Conference on Computational Molecular Biology (Recomb 2001) 2001
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HumanbiologieStuttgart (2014) 446 Seiten
(UTB ; 4130)ISBN: 978-3-8252-4479-8