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Universitätsklinikum Essen, Medizinisches Forschungszentrum, Raum 3.016
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Hufelandstr. 55
45147 Essen
45147 Essen
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Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Physiologie
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Blockade of ß-Adrenergic Receptors by Nebivolol Enables Tumor Control Potential for Uveal Melanoma in 3D Tumor Spheroids and 2D CulturesIn: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 6,ISSN: 1422-0067; 1661-6596Online Volltext: dx.doi.org/ (Open Access)
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Chick Chorioallantoic Membrane as a Patient-Derived Xenograft Model for Uveal Melanoma : Imaging Modalities for Growth and Vascular EvaluationIn: Cancers Jg. 2023 (2023) Nr. 15,ISSN: 2072-6694Online Volltext: dx.doi.org/ (Open Access)
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An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' OrbitopathyIn: Thyroid Jg. 32 (2022) Nr. 3, S. 283 - 293ISSN: 1557-9077; 1050-7256Online Volltext: dx.doi.org/
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Calcium Electroporation Reduces Viability and Proliferation Capacity of Four Uveal Melanoma Cell Lines in 2D and 3D CulturesIn: Cancers Jg. 14 (2022) Nr. 12,ISSN: 2072-6694Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The Adrenergic Receptor Antagonist Carvedilol Elicits Anti-Tumor Responses in Uveal Melanoma 3D Tumor Spheroids and May Serve as Co-Adjuvant Therapy with RadiationIn: Cancers Jg. 14 (2022) Nr. 13,ISSN: 2072-6694Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Electrochemotherapy with bleomycin enhances radiosensitivity of uveal melanomas : First in vitro results in 3d cultures of primary uveal melanoma cell linesIn: Cancers Jg. 13 (2021) Nr. 12,ISSN: 2072-6694Online Volltext: dx.doi.org/ (Open Access)
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Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced diseaseIn: Microbiome Jg. 9 (2021) Nr. 1,ISSN: 2049-2618Online Volltext: dx.doi.org/ (Open Access)
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Optimisation of the Chicken Chorioallantoic Membrane Assay in Uveal Melanoma ResearchIn: Pharmaceutics Jg. 14 (2021) Nr. 1,ISSN: 1999-4923Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Predicting the Course of Graves’ Orbitopathy Using Serially Measured TSH-Receptor Autoantibodies by Automated Binding Immunoassays and the Functional BioassayIn: Hormone and Metabolic Research Jg. 53 (2021) Nr. 07, S. 435 - 443ISSN: 1439-4286; 0018-5043Online Volltext: dx.doi.org/ (Open Access)
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Predicting the Relapse of Hyperthyroidism in Treated Graves’ Disease with Orbitopathy by Serial Measurements of TSH-Receptor AutoantibodiesIn: Hormone and Metabolic Research Jg. 53 (2021) Nr. 4, S. 235 - 244ISSN: 1439-4286; 0018-5043Online Volltext: dx.doi.org/ (Open Access)
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Lessons from mouse models of Graves’ diseaseIn: Endocrine Jg. 68 (2020) Nr. 2, S. 265 - 270ISSN: 1559-0100; 1355-008X; 0969-711XOnline Volltext: dx.doi.org/ (Open Access)
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Search of reference biomarkers reflecting orbital tissue remodeling in the course of Graves' orbitopathyIn: Folia Histochemica et Cytobiologica Jg. 1 (2020) Nr. 1, S. 37 - 45ISSN: 1897-5631; 0239-8508Online Volltext: dx.doi.org/ (Open Access)
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Update endokrine OrbitopathieIn: Augenheilkunde up2date Jg. 10 (2020) Nr. 02, S. 127 - 143ISSN: 1616-9719; 1616-9735Online Volltext: dx.doi.org/
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A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' OrbitopathyIn: Thyroid Jg. 29 (2019) Nr. 1, S. 111 - 123ISSN: 1557-9077; 1050-7256Online Volltext: dx.doi.org/
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Fingolimod Improves the Outcome of Experimental Graves' Disease and Associated Orbitopathy by Modulating the Autoimmune Response to the Thyroid-Stimulating Hormone ReceptorIn: Thyroid Jg. 29 (2019) Nr. 9, S. 1286 - 1301ISSN: 1557-9077; 1050-7256Online Volltext: dx.doi.org/
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Immunotherapy with fingolimod improves outcome of experimental Graves disease and associated orbitopathy by modulating autoimmune response to thyroid stimulating hormone receptorIn: Investigative Ophthalmology & Visual Science, IOVS Jg. 60 (2019) Nr. 9,ISSN: 1552-5783; 0146-0404
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CD40 Enhances Sphingolipids in Orbital Fibroblasts : Potential Role of Sphingosine-1-Phosphate in Inflammatory T-Cell Migration in Graves' OrbitopathyIn: Investigative Ophthalmology & Visual Science, IOVS Jg. 59 (2018) Nr. 13, S. 5391 - 5397ISSN: 1552-5783; 0146-0404Online Volltext: dx.doi.org/ (Open Access)
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Genetic immunization with mouse thyrotrophin hormone receptor plasmid breaks self-tolerance for a murine model of autoimmune thyroid disease and Graves' orbitopathyIn: Clinical and Experimental Immunology Jg. 191 (2018) Nr. 3, S. 255 - 267ISSN: 1365-2249; 0009-9104Online Volltext: dx.doi.org/ (Open Access)
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Graves’ orbitopathy occurs sex-independently in an autoimmune hyperthyroid mouse modelIn: Scientific Reports Jg. 8 (2018) S. 13096ISSN: 2045-2322Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Gut Microbiome in BALB/c and C57BL/6J Mice Undergoing Experimental Thyroid Autoimmunity Associate with Differences in Immunological Responses and Thyroid FunctionIn: Hormone and Metabolic Research Jg. 50 (2018) Nr. 12, S. 932 - 941ISSN: 1439-4286; 0018-5043Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Gut microbiota in experimental murine model of Graves' orbitopathy established in different environments may modulate clinical presentation of diseaseIn: Microbiome Jg. 6 (2018) Nr. 1, S. 97ISSN: 2049-2618Online Volltext: dx.doi.org/ (Open Access)
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Multimodal assessment of orbital immune cell infiltration and tissue remodeling during development of graves disease by ¹H¹⁹F MRIIn: Magnetic Resonance in Medicine Jg. 80 (2018) Nr. 2, S. 711 - 718ISSN: 1522-2594; 0740-3194Online Volltext: dx.doi.org/
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Noninflammatory diffuse follicular hypertrophy/hyperplasia of graves disease : Morphometric evaluation in an experimental mouse modelIn: European Thyroid journal Jg. 7 (2018) Nr. 3, S. 111 - 119ISSN: 2235-0640; 2235-0802Online Volltext: dx.doi.org/ (Open Access)
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Molecular tweezers inhibit PARP-1 by a new mechanismIn: European Journal of Organic Chemistry (2017) Nr. 16, S. 2223 - 2229ISSN: 1099-0690; 0075-4617; 0170-2041; 0365-5490; 0947-3440; 1434-193X; 1434-243XOnline Volltext: dx.doi.org/
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Comparative assessment of female mouse model of Graves' orbitopathy under different environments, accompanied by proinflammatory cytokine and T-cell responses to thyrotropin hormone receptor antigenIn: Endocrinology Jg. 157 (2016) Nr. 4, S. 1673 - 1682ISSN: 1945-7170; 0013-7227Online Volltext: dx.doi.org/ (Open Access)
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Endokrine OrbitopathieIn: Klinische Monatsblätter für Augenheilkunde Jg. 233 (2016) Nr. 12, S. 1385 - 1407ISSN: 0344-6387; 0023-2165; 1439-3999; 0344-6360Online Volltext: dx.doi.org/
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Endokrine OrbitopathieIn: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Jg. 113 (2016) Nr. 4, S. 349 - 366ISSN: 1433-0423; 0941-293XOnline Volltext: dx.doi.org/
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Endokrine OrbitopathieIn: Augenheilkund Up2date Jg. 6 (2016) Nr. 4, S. 265 - 285ISSN: 1616-9719Online Volltext: dx.doi.org/
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Hypoxia-Dependent HIF-1 Activation Impacts on Tissue Remodeling in Graves' Ophthalmopathy-Implications for SmokingIn: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 101 (2016) Nr. 12, S. 4834 - 4842ISSN: 0021-972X; 1945-7197Online Volltext: dx.doi.org/
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Pathogenic Phenotype of Adipogenesis and Hyaluronan in Orbital Fibroblasts From Female Graves' Orbitopathy Mouse ModelIn: Endocrinology Jg. 157 (2016) Nr. 10, S. 3771 - 3778ISSN: 1945-7170; 0013-7227Online Volltext: dx.doi.org/
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Erratum: Modeling Graves' Orbitopathy in Experimental Graves' DiseaseIn: Hormone and Metabolic Research Jg. 47 (2015) Nr. 10, S. e4ISSN: 0018-5043Online Volltext: dx.doi.org/
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Modeling Graves' Orbitopathy in Experimental Graves' DiseaseIn: Hormone and metabolic research Jg. 47 (2015) Nr. 10, S. 797 - 803ISSN: 0018-5043; 1439-4286Online Volltext: dx.doi.org/
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Orbital fibroblasts from graves' orbitopathy patients share functional and immunophenotypic properties with mesenchymal stem/stromal cellsIn: Investigative Ophthalmology & Visual Science, IOVS Jg. 56 (2015) Nr. 11, S. 6549 - 6557ISSN: 1552-5783; 0146-0404Online Volltext: dx.doi.org/ (Open Access)
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Type I cell ROS kinetics under hypoxia in the intact mouse carotid body ex vivo : a FRET-based studyIn: American Journal of Physiology: Lung Cellular and Molecular Physiology Jg. 308 (2015) Nr. 1, S. C61 - C67ISSN: 1040-0605; 1522-1504Online Volltext: dx.doi.org/
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Current Insights into Animal Models of Graves’ Disease and OrbitopathyIn: Hormone and Metabolic Research Jg. 45 (2013) Nr. 8, S. 549 - 555ISSN: 0018-5043; 1439-4286Online Volltext: dx.doi.org/
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Examination of orbital tissues in murine models of graves' disease reveals expression of UCP-1 and the TSHR in retrobulbar adipose tissuesIn: Hormone and Metabolic Research Jg. 45 (2013) Nr. 6, S. 401 - 407ISSN: 1439-4286; 0018-5043Online Volltext: dx.doi.org/
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Rocket fuel for the quantification of S-nitrosothiols : highly specific reduction of S-nitrosothiols to thiols by methylhydrazineIn: Free Radical Research Jg. 47 (2013) Nr. 2, S. 104 - 115ISSN: 1029-2470; 1071-5762; 8755-0199Online Volltext: dx.doi.org/
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Update endokrine OrbitopathieIn: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Jg. 110 (2013) Nr. 11, S. 1079 - 1096ISSN: 1433-0423; 0941-293XOnline Volltext: dx.doi.org/
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Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signallingIn: Journal of Cell Science Jg. 125 (2012) Nr. 21, S. 5168 - 5176ISSN: 0021-9533; 1477-9137Online Volltext: dx.doi.org/
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Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxiaIn: Free Radical Research Jg. 46 (2012) Nr. 6, S. 705 - 717ISSN: 1029-2470; 1071-5762; 8755-0199Online Volltext: dx.doi.org/
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Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signalingIn: Nucleic Acids Research Jg. 40 (2012) Nr. 5, S. 1928 - 1943ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access)
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A Novel Mechanism Involved in the Pathogenesis of Graves Ophthalmopathy (GO) : Clathrin Is a Possible Targeting Molecule for Inhibiting Local Immune Response in the OrbitIn: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 96 (2011) Nr. 11, S. E1727 - 1736ISSN: 0021-972X; 1945-7197Online Volltext: dx.doi.org/
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Multifocal animated imaging of changes in cellular oxygen and calcium concentrations and membrane potential within the intact adult mouse carotid body ex vivoIn: American Journal of Physiology: Cell Physiology Jg. 301 (2011) Nr. 2, S. C266 - 71ISSN: 1522-1563; 0002-9513; 0363-6143Online Volltext: dx.doi.org/
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Complex Regulation of the Transactivation Function of Hypoxia-inducible Factor-1α by Direct Interaction with Two Distinct Domains of the CREB-binding Protein/p300In: The Journal of Biological Chemistry (JBC) Jg. 285 (2010) Nr. 4, S. 2601 - 2609ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/
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Oxygen-sensing under the influence of nitric oxideIn: Cellular Signalling Jg. 22 (2010) Nr. 3, S. 349 - 356ISSN: 1873-3913; 0898-6568Online Volltext: dx.doi.org/
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Role of N-acetyl-N-nitroso-tryptophan as nitric oxide donor in the modulation of HIF-1-dependent signalingIn: Biological Chemistry Jg. 391 (2010) Nr. 5, S. 533 - 540ISSN: 1437-4315; 1431-6730Online Volltext: dx.doi.org/
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Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cellsIn: Blood Jg. 100 (2002) Nr. 7, S. 2623 - 2628ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
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Measurement of ROS levels and membrane potential dynamics in the intact carotid body ex vivoIn: Arterial Chemoreceptors in Physiology and Pathophysiology / XVIIIth Meeting of the International Society for Arterial Chemoreception ; Leeds, June 30 - July 3, 2014 / Peers, Chris; Kumar, Prem; Wyatt, Christopher; Gauda, Estelle; Nurse, Colin A.; Prabhakar, Nanduri (Hrsg.) 2015, S. 55 - 59ISBN: 978-3-319-18439-5; 978-3-319-18440-1Online Volltext: dx.doi.org/
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Die Regulation der Hypoxie-abhängigen GenexpressionUniversität Duisburg-Essen (2010) CD-ROM