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Universitätsklinikum Essen, Medizinisches Forschungszentrum, Raum 3.016
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Hufelandstr. 55
45147 Essen
45147 Essen
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Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Physiologie
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Calcium Electroporation versus Electrochemotherapy with Bleomycin in an In Vivo CAM-Based Uveal Melanoma Xenograft ModelIn: International Journal of Molecular Sciences (IJMS) Jg. 25 (2024) Nr. 2, 938Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Electroporation with Calcium or Bleomycin : First Application in an In Vivo Uveal Melanoma Patient-Derived Xenograft ModelIn: Pharmaceuticals Jg. 17 (2024) Nr. 7, 905Online Volltext: dx.doi.org/ (Open Access)
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The Chick Chorioallantoic Membrane as a Xenograft Model for the Quantitative Analysis of Uveal Melanoma Metastasis in Multiple OrgansIn: Cells Jg. 13 (2024) Nr. 14, 1169Online Volltext: dx.doi.org/ (Open Access)
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Wolfram-silicone implants as effective radiation shielding for ocular brachytherapy : dosimetric features and in vivo animal study on biocompatibilityIn: Canadian Journal of Ophthalmology (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Blockade of ß-Adrenergic Receptors by Nebivolol Enables Tumor Control Potential for Uveal Melanoma in 3D Tumor Spheroids and 2D CulturesIn: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 6,Online Volltext: dx.doi.org/ (Open Access)
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Chick Chorioallantoic Membrane as a Patient-Derived Xenograft Model for Uveal Melanoma : Imaging Modalities for Growth and Vascular EvaluationIn: Cancers Jg. 2023 (2023) Nr. 15, 1436Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Macrophage-Orbital Fibroblast Interaction and Hypoxia Promote Inflammation and Adipogenesis in Graves' OrbitopathyIn: Endocrinology Jg. 164 (2023) Nr. 2, bqac203Online Volltext: dx.doi.org/
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An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' OrbitopathyIn: Thyroid Jg. 32 (2022) Nr. 3, S. 283 - 293Online Volltext: dx.doi.org/
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Calcium Electroporation Reduces Viability and Proliferation Capacity of Four Uveal Melanoma Cell Lines in 2D and 3D CulturesIn: Cancers Jg. 14 (2022) Nr. 12, 2889Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Optimisation of the Chicken Chorioallantoic Membrane Assay in Uveal Melanoma ResearchIn: Pharmaceutics Jg. 14 (2022) Nr. 1, 13Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The Adrenergic Receptor Antagonist Carvedilol Elicits Anti-Tumor Responses in Uveal Melanoma 3D Tumor Spheroids and May Serve as Co-Adjuvant Therapy with RadiationIn: Cancers Jg. 14 (2022) Nr. 13, 3097Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Electrochemotherapy with bleomycin enhances radiosensitivity of uveal melanomas : First in vitro results in 3d cultures of primary uveal melanoma cell linesIn: Cancers Jg. 13 (2021) Nr. 12, 3086Online Volltext: dx.doi.org/ (Open Access)
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Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced diseaseIn: Microbiome Jg. 9 (2021) Nr. 1, 45Online Volltext: dx.doi.org/ (Open Access)
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Predicting the Course of Graves’ Orbitopathy Using Serially Measured TSH-Receptor Autoantibodies by Automated Binding Immunoassays and the Functional BioassayIn: Hormone and Metabolic Research Jg. 53 (2021) Nr. 07, S. 435 - 443Online Volltext: dx.doi.org/ (Open Access)
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Predicting the Relapse of Hyperthyroidism in Treated Graves’ Disease with Orbitopathy by Serial Measurements of TSH-Receptor AutoantibodiesIn: Hormone and Metabolic Research Jg. 53 (2021) Nr. 4, S. 235 - 244Online Volltext: dx.doi.org/ (Open Access)
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Lessons from mouse models of Graves’ diseaseIn: Endocrine Jg. 68 (2020) Nr. 2, S. 265 - 270Online Volltext: dx.doi.org/ (Open Access)
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Search of reference biomarkers reflecting orbital tissue remodeling in the course of Graves' orbitopathyIn: Folia Histochemica et Cytobiologica Jg. 1 (2020) Nr. 1, S. 37 - 45Online Volltext: dx.doi.org/ (Open Access)
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Update endokrine OrbitopathieIn: Augenheilkunde up2date Jg. 10 (2020) Nr. 02, S. 127 - 143Online Volltext: dx.doi.org/
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A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' OrbitopathyIn: Thyroid Jg. 29 (2019) Nr. 1, S. 111 - 123Online Volltext: dx.doi.org/
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Fingolimod Improves the Outcome of Experimental Graves' Disease and Associated Orbitopathy by Modulating the Autoimmune Response to the Thyroid-Stimulating Hormone ReceptorIn: Thyroid Jg. 29 (2019) Nr. 9, S. 1286 - 1301Online Volltext: dx.doi.org/
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Immunotherapy with fingolimod improves outcome of experimental Graves disease and associated orbitopathy by modulating autoimmune response to thyroid stimulating hormone receptorIn: Investigative Ophthalmology & Visual Science, IOVS Jg. 60 (2019) Nr. 9,
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CD40 Enhances Sphingolipids in Orbital Fibroblasts : Potential Role of Sphingosine-1-Phosphate in Inflammatory T-Cell Migration in Graves' OrbitopathyIn: Investigative Ophthalmology & Visual Science, IOVS Jg. 59 (2018) Nr. 13, S. 5391 - 5397Online Volltext: dx.doi.org/ (Open Access)
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Genetic immunization with mouse thyrotrophin hormone receptor plasmid breaks self-tolerance for a murine model of autoimmune thyroid disease and Graves' orbitopathyIn: Clinical and Experimental Immunology Jg. 191 (2018) Nr. 3, S. 255 - 267Online Volltext: dx.doi.org/ (Open Access)
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Graves’ orbitopathy occurs sex-independently in an autoimmune hyperthyroid mouse modelIn: Scientific Reports Jg. 8 (2018) S. 13096Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Gut Microbiome in BALB/c and C57BL/6J Mice Undergoing Experimental Thyroid Autoimmunity Associate with Differences in Immunological Responses and Thyroid FunctionIn: Hormone and Metabolic Research Jg. 50 (2018) Nr. 12, S. 932 - 941Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Gut microbiota in experimental murine model of Graves' orbitopathy established in different environments may modulate clinical presentation of diseaseIn: Microbiome Jg. 6 (2018) Nr. 1, 97Online Volltext: dx.doi.org/ (Open Access)
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Multimodal assessment of orbital immune cell infiltration and tissue remodeling during development of graves disease by ¹H¹⁹F MRIIn: Magnetic Resonance in Medicine Jg. 80 (2018) Nr. 2, S. 711 - 718Online Volltext: dx.doi.org/
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Noninflammatory diffuse follicular hypertrophy/hyperplasia of graves disease : Morphometric evaluation in an experimental mouse modelIn: European Thyroid Journal Jg. 7 (2018) Nr. 3, S. 111 - 119Online Volltext: dx.doi.org/ (Open Access)
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Molecular tweezers inhibit PARP-1 by a new mechanismIn: European Journal of Organic Chemistry (2017) Nr. 16, S. 2223 - 2229Online Volltext: dx.doi.org/
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Comparative assessment of female mouse model of Graves' orbitopathy under different environments, accompanied by proinflammatory cytokine and T-cell responses to thyrotropin hormone receptor antigenIn: Endocrinology Jg. 157 (2016) Nr. 4, S. 1673 - 1682Online Volltext: dx.doi.org/ (Open Access)
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Endokrine OrbitopathieIn: Augenheilkunde up2date Jg. 6 (2016) Nr. 4, S. 265 - 285Online Volltext: dx.doi.org/
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Endokrine OrbitopathieIn: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Jg. 113 (2016) Nr. 4, S. 349 - 366Online Volltext: dx.doi.org/
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Endokrine OrbitopathieIn: Klinische Monatsblätter für Augenheilkunde Jg. 233 (2016) Nr. 12, S. 1385 - 1407Online Volltext: dx.doi.org/
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Hypoxia-Dependent HIF-1 Activation Impacts on Tissue Remodeling in Graves' Ophthalmopathy-Implications for SmokingIn: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 101 (2016) Nr. 12, S. 4834 - 4842Online Volltext: dx.doi.org/
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Pathogenic Phenotype of Adipogenesis and Hyaluronan in Orbital Fibroblasts From Female Graves' Orbitopathy Mouse ModelIn: Endocrinology Jg. 157 (2016) Nr. 10, S. 3771 - 3778Online Volltext: dx.doi.org/
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Erratum: Modeling Graves' Orbitopathy in Experimental Graves' DiseaseIn: Hormone and Metabolic Research Jg. 47 (2015) Nr. 10, S. e4Online Volltext: dx.doi.org/
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Modeling Graves' Orbitopathy in Experimental Graves' DiseaseIn: Hormone and Metabolic Research Jg. 47 (2015) Nr. 10, S. 797 - 803Online Volltext: dx.doi.org/
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Orbital fibroblasts from graves' orbitopathy patients share functional and immunophenotypic properties with mesenchymal stem/stromal cellsIn: Investigative Ophthalmology & Visual Science, IOVS Jg. 56 (2015) Nr. 11, S. 6549 - 6557Online Volltext: dx.doi.org/ (Open Access)
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Type I cell ROS kinetics under hypoxia in the intact mouse carotid body ex vivo : a FRET-based studyIn: American Journal of Physiology: Lung Cellular and Molecular Physiology Jg. 308 (2015) Nr. 1, S. C61 - C67Online Volltext: dx.doi.org/
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Current Insights into Animal Models of Graves’ Disease and OrbitopathyIn: Hormone and Metabolic Research Jg. 45 (2013) Nr. 8, S. 549 - 555Online Volltext: dx.doi.org/
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Examination of orbital tissues in murine models of graves' disease reveals expression of UCP-1 and the TSHR in retrobulbar adipose tissuesIn: Hormone and Metabolic Research Jg. 45 (2013) Nr. 6, S. 401 - 407Online Volltext: dx.doi.org/
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Rocket fuel for the quantification of S-nitrosothiols : highly specific reduction of S-nitrosothiols to thiols by methylhydrazineIn: Free Radical Research Jg. 47 (2013) Nr. 2, S. 104 - 115Online Volltext: dx.doi.org/
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Update endokrine OrbitopathieIn: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Jg. 110 (2013) Nr. 11, S. 1079 - 1096Online Volltext: dx.doi.org/
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Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signallingIn: Journal of Cell Science Jg. 125 (2012) Nr. 21, S. 5168 - 5176Online Volltext: dx.doi.org/
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Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxiaIn: Free Radical Research Jg. 46 (2012) Nr. 6, S. 705 - 717Online Volltext: dx.doi.org/
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Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signalingIn: Nucleic Acids Research Jg. 40 (2012) Nr. 5, S. 1928 - 1943Online Volltext: dx.doi.org/ (Open Access)
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A Novel Mechanism Involved in the Pathogenesis of Graves Ophthalmopathy (GO) : Clathrin Is a Possible Targeting Molecule for Inhibiting Local Immune Response in the OrbitIn: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 96 (2011) Nr. 11, S. E1727 - 1736Online Volltext: dx.doi.org/
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Multifocal animated imaging of changes in cellular oxygen and calcium concentrations and membrane potential within the intact adult mouse carotid body ex vivoIn: American Journal of Physiology: Cell Physiology Jg. 301 (2011) Nr. 2, S. C266 - 71Online Volltext: dx.doi.org/
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Complex Regulation of the Transactivation Function of Hypoxia-inducible Factor-1α by Direct Interaction with Two Distinct Domains of the CREB-binding Protein/p300In: The Journal of Biological Chemistry (JBC) Jg. 285 (2010) Nr. 4, S. 2601 - 2609Online Volltext: dx.doi.org/
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Oxygen-sensing under the influence of nitric oxideIn: Cellular Signalling Jg. 22 (2010) Nr. 3, S. 349 - 356Online Volltext: dx.doi.org/
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Role of N-acetyl-N-nitroso-tryptophan as nitric oxide donor in the modulation of HIF-1-dependent signalingIn: Biological Chemistry Jg. 391 (2010) Nr. 5, S. 533 - 540Online Volltext: dx.doi.org/
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Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cellsIn: Blood Jg. 100 (2002) Nr. 7, S. 2623 - 2628Online Volltext: dx.doi.org/
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Measurement of ROS levels and membrane potential dynamics in the intact carotid body ex vivoIn: Arterial Chemoreceptors in Physiology and Pathophysiology / XVIIIth Meeting of the International Society for Arterial Chemoreception ; Leeds, June 30 - July 3, 2014 / Peers, Chris; Kumar, Prem; Wyatt, Christopher; Gauda, Estelle; Nurse, Colin A.; Prabhakar, Nanduri (Hrsg.) 2015, S. 55 - 59Online Volltext: dx.doi.org/
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Die Regulation der Hypoxie-abhängigen GenexpressionUniversität Duisburg-Essen (2010) CD-ROM