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Mitglied/er, Innere Klinik (Tumorforschung)
Medizinische Fakultät UK Essen
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Neutropenia-related aspergillosis in non-transplant haematological patients hospitalised under ambient air versus purified air conditionsIn: Mycoses, Jg. 66, 2023, Nr. 6, S. 505 – 514DOI (Open Access)
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Air pollution and polyclonal elevation of serum free light chains : An assessment of adaptive immune responses in the prospective heinz nixdorf recall studyIn: Environmental Health Perspectives, Jg. 129, 2021, Nr. 2, S. 027004DOI (Open Access)
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Impact of shift work on the risk of depressionIn: Chronobiology International, Jg. 38, 2021, Nr. 12, S. 1761 – 1775
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Associations between shift work and risk of colorectal cancer in two German cohort studiesIn: Chronobiology International, Jg. 37, 2020, Nr. 8, S. 1235 – 1243
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Efficacy of the GMALL-B-ALL/NHL2002 protocol in Burkitt leukemia/lymphoma and aggressive non-Hodgkin-lymphomas with or without CNS involvementIn: European Journal of Haematology, Jg. 102, 2019, Nr. 3, S. 241 – 250
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Socioeconomic Position is Positively Associated with Monoclonal Gammopathy of Undetermined Significance in a Population-based Cohort StudyIn: Annals of Hematology, Jg. 98, 2019, Nr. 12, S. 2761 – 2767
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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individualsIn: Nature Genetics, Jg. 50, 2018, Nr. 8, S. 1112 – 1121DOI, Online Volltext (Open Access)
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Light chain monoclonal gammopathy of undetermined significance is characterized by a high disappearance rate and low risk of progression on longitudinal analysisIn: Annals of Hematology, Jg. 97, 2018, Nr. 8, S. 1463 – 1469
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An Expanded Genome-Wide Association Study of Type 2 Diabetes in EuropeansIn: Diabetes, Jg. 66, 2017, Nr. 11, S. 2888 – 2902DOI, Online Volltext (Open Access)
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Associations between former exposure to manganese and olfaction in an elderly population : results from the Heinz Nixdorf Recall StudyIn: NeuroToxicology, Jg. 58, 2017, S. 58 – 65
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Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk lociIn: Scientific Reports, Jg. 7, 2017, S. 41071DOI (Open Access)
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Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS).In: International Journal of Molecular Sciences (IJMS), Jg. 18, 2017, Nr. 6DOI, Online Volltext (Open Access)
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Incidence of second cancers after radiotherapy and systemic chemotherapy in heritable retinoblastoma survivors : a report from the German reference centerIn: Pediatric Blood and Cancer, Jg. 64, 2017, Nr. 1, S. 71 – 80
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Is long-term particulate matter and nitrogen dioxide air pollution associated with incident monoclonal gammopathy of undetermined significance (MGUS)? : An analysis of the Heinz Nixdorf Recall studyIn: Environment International, Jg. 108, 2017, S. 237 – 245
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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillationIn: Nature Genetics, Jg. 49, 2017, Nr. 6, S. 946 – 952DOI, Online Volltext (Open Access)
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Longitudinal analysis of light-chain monoclonal gammopathy of undetermined significance-10-year follow up of the population-based Heinz Nixdorf Recall studyIn: Oncology Research and Treatment, Jg. 40, 2017, Nr. Suppl. 3, S. 81 Abstract P292
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Occupational exposure to manganese and fine motor skills in elderly men : Results from the Heinz Nixdorf Recall StudyIn: Annals of Work Exposures and Health, Jg. 61, 2017, Nr. 9, S. 1118 – 1131DOI, Online Volltext (Open Access)
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Prolongation of the QTc interval in HIV-infected individuals compared to the general populationIn: Infection - A Journal of Infectious Disease, Jg. 45, 2017, Nr. 5, S. 659 – 667
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Shift work and the incidence of prostate cancer : a10-year follow-up of a German population-based cohort studyIn: Scandinavian Journal of Work, Environment & Health, Jg. 43, 2017, Nr. 6, S. 560 – 568DOI (Open Access)
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Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and LifesIn: Circulation: Genomic and Precision Medicine, Jg. 10, 2017, Nr. 2DOI (Open Access)
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Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and Lifestyle)In: Circulation: Genomic and Precision Medicine, Jg. 10, 2017, Nr. 2DOI (Open Access)
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The distribution of blood concentrations of lead (Pb), cadmium (Cd), chromium (Cr) and manganese (Mn) in residents of the German Ruhr area and its potential association with occupational exposure in metal industry and/or other risk factorsIn: International Journal of Hygiene and Environmental Health, Jg. 220, 2017, Nr. 6, S. 998 – 1005
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A Randomized Trial of Daily Prednisone versus Pulsed Dexamethasone in Treatment-Naïve Adult Patients with Immune Thrombocytopenia : EIS 2002 StudyIn: Acta Haematologica, Jg. 136, 2016, Nr. 2, S. 101 – 107
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Anemia and Mild Cognitive Impairment in the German General PopulationIn: Journal of Alzheimer's Disease, Jg. 49, 2016, Nr. 4, S. 1031 – 1042
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Evidence of Inbreeding in Hodgkin LymphomaIn: PLoS ONE, Jg. 11, 2016, Nr. 4, S. e0154259DOI (Open Access)
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Genome-wide association study identifies 74 loci associated with educational attainmentIn: Nature, Jg. 533, 2016, Nr. 7604, S. 539 – 542DOI, Online Volltext (Open Access)
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How Eye-Preserving Therapy Affects Long-Term Overall Survival in Heritable Retinoblastoma SurvivorsIn: Journal of Clinical Oncology (JCO), Jg. 34, 2016, Nr. 26, S. 3183 – 3188
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Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis : a prospective observational trialIn: BMC Anesthesiology, Jg. 16, 2016, Nr. 1, S. 61DOI (Open Access)
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Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemiaIn: Leukemia and Lymphoma, Jg. 57, 2016, Nr. 3, S. 590 – 595
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Update of the effect estimates for common variants associated with carotid intima media thickness within four independent samples : The Bonn IMT Family Study, the Heinz Nixdorf Recall Study, the SAPHIR Study and the Bruneck StudyIn: Atherosclerosis, Jg. 249, 2016, S. 83 – 87
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility lociIn: Nature Genetics, Jg. 47, 2015, Nr. 12, S. 1415 – 1425DOI, Online Volltext (Open Access)
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Heritability estimates on Hodgkin's lymphoma : a genomic- versus population-based approachIn: European Journal of Human Genetics, Jg. 23, 2015, Nr. 6, S. 824 – 830DOI (Open Access)
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Long-term residential exposure to urban air pollution, and repeated measures of systemic blood markers of inflammation and coagulationIn: Occupational and Environmental Medicine (eOEM), Jg. 72, 2015, Nr. 9, S. 656 – 663
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Outcomes of Primary and Secondary Transformed B-Cell LymphomasIn: Blood, Jg. 126, 2015, Nr. 23
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Pediatric second primary malignancies after retinoblastoma treatmentIn: Pediatric Blood and Cancer, Jg. 62, 2015, Nr. 10, S. 1799 – 1804DOI (Open Access)
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Prolongation of QTc interval in HIV-infected individuals compared to the general population is not caused by antiretroviral therapyIn: Journal of the International AIDS Society, Jg. 18, 2015, Nr. Suppl. 4, S. 20479DOI (Open Access)
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Replication effort for common variants associated with carotid intima media thickness within four independent samplesIn: Genetic Epidemiology, Jg. 39, 2015, Nr. 7, S. 550 – 551
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The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2AIn: Scientific Reports, Jg. 5, 2015, S. 15065DOI (Open Access)
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Aging of blood can be tracked by DNA methylation changes at just three CpG sitesIn: Genome Biology, Jg. 15, 2014, Nr. 2, R24DOI (Open Access)
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Agreement between different survey instruments to assess incident and prevalent tumors and medical records – results of the Heinz Nixdorf Recall StudyIn: Cancer Epidemiology, Jg. 38, 2014, Nr. 2, S. 181 – 192
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarizationIn: Nature Genetics, Jg. 46, 2014, Nr. 8, S. 826 – 836DOI, Online Volltext (Open Access)
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Influence of welding fume on systemic iron statusIn: The Annals of Occupational Hygiene, Jg. 58, 2014, Nr. 9, S. 1143 – 1154
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Inherited genetic susceptibility to monoclonal gammopathy of unknown significanceIn: Blood, Jg. 123, 2014, Nr. 16, S. 2513 – 2517
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Rates of cardiovascular events and deaths are associated with advanced stages of HIV-infection : results of the HIV HEART study 7, 5 year follow-upIn: Journal of the International AIDS Society, Jg. 17, 2014, Nr. Suppl. 3, S. 36 – 37DOI (Open Access)
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Vergleich extrakorporaler Leberunterstützungsverfahren – Albumin-Dialyse versus Plasmaaustausch – bei akut-auf-chronischem LeberversagenIn: Deutsche Medizinische Wochenschrift - DMW, Jg. 139, 2014, Nr. 33, S. 1653 – 1658
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A Randomized Trial Of Daily Prednisone Versus Pulsed Dexamethasone In Treatment Naïve Patients With Idiopathic Thrombocytopenic PurpuraIn: Blood, Jg. 122, 2013, Nr. 21, S. 325
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B-type natriuretic peptide elevation is more frequent in HIV plus patients compared to the general populationIn: Antiviral Therapy, Jg. 18, 2013, Nr. Suppl. 3, S. A41 – A42
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Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma riskIn: Nature Genetics, Jg. 45, 2013, Nr. 10, S. 1221 – 1225
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Deciphering the 8q24.21 association for gliomaIn: Human Molecular Genetics, Jg. 22, 2013, Nr. 11, S. 2293 – 2302
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Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1(+) effector memory phenotypeIn: Cancer Immunology, Immunotherapy, Jg. 62, 2013, Nr. 11, S. 1697 – 1709
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Framingham risk score and cardiovascular risk profiles in HIV+ patients and HIV- controls differ by sexIn: European Heart Journal, Jg. 34, 2013, Nr. Suppl. 1, S. P5164
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Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222.In: British Journal of Cancer (BJC), Jg. 108, 2013, Nr. 10, S. 2178 – 2185
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Prevalence and incidence of anemia in the German Heinz Nixdorf Recall StudyIn: Annals of Hematology, Jg. 92, 2013, Nr. 6, S. 731 – 737
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Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic LeukemiaIn: PLoS ONE, Jg. 23, 2013, Nr. 8, S. e72107DOI (Open Access)
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Psychotropic drugs are prescribed more frequently in HIV-positive patients compared to the general population. Data from two German prospective cohorts : Heinz Nixdorf Recall Study and HIV HEART StudyIn: Antiviral Therapy, Jg. 18, 2013, Nr. Suppl. 3, S. A77 – A78
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The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myelomaIn: Nature Genetics, Jg. 45, 2013, Nr. 5, S. 522 – 525
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Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotypeIn: Blood, Jg. 122, 2013, Nr. 19, S. 3298 – 3307
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Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphomaIn: Nature Communications, 2013, Nr. 4, S. 2549
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Die Heinz Nixdorf Recall StudieIn: Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, Jg. 55, 2012, Nr. 6-7, S. 809 – 815
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Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic LeukemiaIn: PLoS ONE, Jg. 7, 2012, Nr. 12, S. e34347DOI (Open Access)
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Evaluation of free light-chain abnormalities as prognostic marker in Binet A stage chronic lymphocytic leukemiaIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 99 – 99
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Krankheitsfaktoren in Populationen : moderne Ansätze der epidemiologischen KrebsforschungIn: Unikate: Berichte aus Forschung und Lehre, 2012, Nr. 42 : Translationale Krebsforschung: Auf dem Weg zu neuen Therapien, S. 8 – 15DOI, Online Volltext (Open Access)
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Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: A novel candidate SNP approachIn: Frontiers in Genetics, Jg. 3, 2012, 203DOI (Open Access)
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Prevalence and progression of monoclonal gammopathy of undetermined significance and light-chain MGUS in GermanyIn: Annals of Hematology, Jg. 91, 2012, Nr. 2, S. 243 – 248
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Progranulin plasma concentration is a novel independent prognostic marker in chronic lymphocytic leukemiaIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 100
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Serum immunoglobulin alterations in patients with chronic hepatitis CIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 142 – 143
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Chromosome 7p11.2 (EGFR) variation influences glioma riskIn: Human Molecular Genetics, Jg. 20, 2011, Nr. 14, S. 2897 – 2904
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Common variation at 10p12.31 near MLLT10 influences meningioma riskIn: Nature Genetics, Jg. 43, 2011, Nr. 9, S. 825 – 827
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Investigating the role of CD38 and functionally related molecular risk factors in the CLL NOD/SCID xenograft modelIn: European Journal of Haematology, Jg. 87, 2011, Nr. 1, S. 10 – 19
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Monoclonal gammopathy of undetermined significance and solid tumor development in the Heinz Nixdorf Recall Study
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,In: Onkologie, Jg. 34, 2011, Nr. Suppl. 6, S. 243 -
705 Increased prevalence of monoclonal b lymphocytosis in patients with chronic Hepatitis CIn: Journal of Hepatology, Jg. 52, 2010, Nr. Suppl. 1, S. S274
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Percentage of smudge cells determined on routine blood smears is a novel prognostic factor in chronic lymphocytic leukemiaIn: Leukemia Research, Jg. 34, 2010, Nr. 7, S. 892 – 898
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Prevalence of monoclonal gammopathy of undetermindes significance in a densley populated, highly industrialized area in Germany
15th Congress of the European Hematology Association, Spain, Barcelona, June 10–13, 2010,In: Haematologica, the hematology journal, Jg. 95, 2010, Nr. Suppl. 2, S. 394, 0949 -
Prevalence of monoclonal gammopathy of undetermined significance in a densely populated, highly industrialized area in Germany
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie, Jg. 33, 2010, Nr. Suppl. 6, S. 95, V321 -
Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemiaIn: European Journal of Haematology, Jg. 83, 2009, Nr. 4, S. 320 – 327
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Expression levels of CD38 on leukemic B cells but not on non-leukemic T cells are comparably stable over time and predict the course of disease in patients with chronic lymphocytic leukemiaIn: Leukemia Research, Jg. 33, 2009, Nr. 6, S. 775 – 778
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Response of pseudomyxoma peritonei to gemcitabineIn: Acta Oncologica, Jg. 45, 2006, Nr. 1, S. 98 – 100
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Long-term overall survival for patients with retinoblastoma : A report from the German referral center from 1940-2008
Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 29 – 30 -
Prevalence, distribution and predictive value on all-cause mortality of clinical relevant extracardiac findings from cardiac CT in the general population : The Heinz Nixdorf Recall StudyIn: European Heart Journal. Oxford: Oxford University Press (OUP), Jg. 36, 2015, Nr. Suppl. 1, S. 348
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Second primary malignancies in children and adolescents after retinoblastoma treatment
47th Congress of the International Society of Paediatric Oncology (SIOP), October 8–11, 2015, Cape Town, South Africa,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 62, 2015, Nr. Suppl. 4, S. S232 -
Brain natriuretic peptide (BNP) as a prognostic parameter for cardiovascular events and death in HV-infected patients
ESC Congress 2014, Barcelona, Spain, 30 August – 3 September 2014,In: European Heart Journal. Oxford: Oxford University Press (OUP), Jg. 35, 2014, Nr. Suppl. 1, S. 231 -
Left ventricular ejection fraction as a prognostic marker for all-cause mortality in HIV-infected patients
ESC Congress 2016, 27 - 31 August, Rome, Italy,In: European Heart Journal. Oxford: Oxford University Press (OUP), Jg. 35, 2014, Nr. Suppl. 1, S. 3 -
Establishment of a real-time PCR assay to quantify the size of a NOTCH1 mutated subclone in chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,In: Onkologie. Basel: Karger, Jg. 36, 2013, Nr. Suppl. 7, S. 60 -
Expansion of a stimulatory natural killer receptor NKp80-expessing CD8+T-cell subset in chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,In: Onkologie. Basel: Karger, Jg. 36, 2013, Nr. Suppl. 7, S. 191 -
Progranulin plasma levels predict time to first treatment and overall survival in chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 196 – 196 -
Comparing the pharmacological effects of the novel Locked Nucleic Acid (LNA) modified antisense Bcl-2 inhibitor SPC2996 and G3139 (oblimersen) in preclinical models of chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 184 -
Cryptochrome 1 (CRY1) promoter methylation is associated with good prognosis in B-cell chronic lymphocytic leukemia (CLL)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 240 – 241 -
Expanded CD8(+) T-cells of murine and human B-CLL are driven into a senescent KLRG1(+) effector memory phenotypeIn: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 201
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Expanded CLL CD8(+) T-Cells Are Driven Into a Senescent KLRG1(+) Effector Memory PhenotypeIn: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 116, 2010, Nr. 21, S. 403
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Investigating the interaction of leukemic B and non-malignant T cells in a novel Rag2-/gamma c-/--xenograft model of human chronic lymphocytic leukemia (CLL)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 202 -
Outpatient management of acute myeloid leukemia after intensive consolidation chemotherapy is feasible and reduces hospital treatment costsIn: Oncology. Basel: Karger, Jg. 33, 2010, Nr. 12, S. 658 – 664
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Prevalence of B cell lymphoproliferative disorders in patients with chronic hepatitis C (CHC)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010, pp 109–206,In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 157 -
Prevalence of Monoclonal Gammopathy of Undetermined Significance (MGUS) and Light-Chain MGUS (LCMGUS) In a Metropolitan Area In GermanyIn: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 116, 2010, Nr. 21, 4037