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Cyrus Khandanpour

Funktionen

  • , Zentrum für Innere Medizin

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Sun, Kaiyan; Jin, Ling; Karolová, Jana; Vorwerk, Jan; Hailfinger, Stephan; Opalka, Bertram; Zapukhlyak, Myroslav; Lenz, Georg; Khandanpour, Cyrus
    Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma
    In: Cancers Jg. 15 (2023) Nr. 8,
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ (Open Access)
  • Xie, Xiaoqing; Patnana, Pradeep Kumar; Frank, Daria; Schütte, Judith; Al-Matary, Yahya; Künstner, Axel; Busch, Hauke; Ahmed, Helal; Liu, Longlong; Engel, Daniel Robert; Dührsen, Ulrich; Rosenbauer, Frank; Von Bubnoff, Nikolas; Lenz, Georg; Khandanpour, Cyrus
    Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs
    In: Frontiers in Cell and Developmental Biology Jg. 11 (2023)
    ISSN: 2296-634X
    Online Volltext: dx.doi.org/ (Open Access)
  • Patnana, Pradeep Kumar; Liu, Longlong; Frank, Daria; Nimmagadda, Subbaiah Chary; Behrens, Matthias; Ahmed, Helal; Xie, Xiaoqing; Liebmann, Marie; Wei, Lanying; Gerdemann, Andrea; Thivakaran, Aniththa; Humpf, Hans-Ulrich; Klotz, Luisa; Dugas, Martin; Varghese, Julian; Trajkovic-Arsic, Marija; Siveke, Jens; Hanenberg, Helmut; Opalka, Bertram; Dührsen, Ulrich; Reinhardt, Christian; Guenther, Ulrich; von Bubnoff, Nikolas; Khandanpour, Cyrus
    Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cells
    In: British Journal of Haematology Jg. 202 (2023) Nr. 5, S. 1033 - 1048
    ISSN: 1365-2141; 0007-1048
    Online Volltext: dx.doi.org/ (Open Access)
  • Frank, Daria; Patnana, Pradeep Kumar; Vorwerk, Jan; Mao, Lianghao; Gopal, Lavanya Mokada; Jung, Noelle; Hennig, Thorben; Ruhnke, Leo; Frenz, Joris Maximillian; Kuppusamy, Maithreyan; Autry, Robert; Wei, Lanying; Sun, Kaiyan; Mohammed Ahmed, Helal Mohammed; Künstner, Axel; Busch, Hauke; Müller, Heiko; Hutter, Stephan; Hoermann, Gregor; Liu, Longlong; Xie, Xiaoqing; Al-Matary, Yahya; Nimmagadda, Subbaiah Chary; Cano, Fiorella Charles; Heuser, Michael; Thol, Felicitas; Göhring, Gudrun; Steinemann, Doris; Thomale, Jürgen; Leitner, Theo; Fischer, Anja; Rad, Roland; Röllig, Christoph; Altmann, Heidi; Kunadt, Desiree; Berdel, Wolfgang E.; Hüve, Jana; Neumann, Felix; Klingauf, Jürgen; Calderon, Virginie; Opalka, Bertram; Dührsen, Ulrich; Rosenbauer, Frank; Dugas, Martin; Varghese, Julian; Reinhardt, Hans Christian; von Bubnoff, Nikolas; Möröy, Tarik; Lenz, Georg; Batcha, Aarif M. N.; Giorgi, Marianna; Selvam, Murugan; Wang, Eunice; McWeeney, Shannon K.; Tyner, Jeffrey W.; Stölzel, Friedrich; Mann, Matthias; Jayavelu, Ashok Kumar; Khandanpour, Cyrus; Mokada Gopal, Lavanya; Ahmed, Helal; Charles Cano, Fiorella
    Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy
    In: Blood (2023) in press
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/ (Open Access)
  • Goldschmidt, Hartmut; Mai, Elias K.; Bertsch, Uta; Fenk, Roland; Nievergall, Eva; Tichy, Diana; Besemer, Britta; Dürig, Jan; Schroers, Roland; von Metzler, Ivana; Hänel, Mathias; Mann, Christoph; Asemissen, Anne M.; Heilmeier, Bernhard; Weinhold, Niels; Huhn, Stefanie; Kriegsmann, Katharina; Luntz, Steffen P.; Holderried, Tobias A W; Trautmann-Grill, Karolin; Gezer, Deniz; Klaiber-Hakimi, Maika; Müller, Martin; Khandanpour, Cyrus; Knauf, Wolfgang; Scheid, Christof; Munder, Markus; Geer, Thomas; Riesenberg, Hendrik; Thomalla, Jörg; Hoffmann, Martin; Raab, Marc S.; Salwender, Hans J.; Weisel, Katja C.; Behringer, Joachim; Bernhard, Helga; Bernhardt, Christiane; Blau, Igor W; Bolling, Claus; Debatin, Daniel; Dingeldein, Gerrit; Ferstl, Barbara; Fest, Claudia; Fronhoffs, Stefan; Fuhrmann, Stephan; Gaska, Tobias; Görner, Martin; Graeven, Ullrich; Grassinger, Jochen; Heinsch, Michael; Held, Gerhard; Hopfer, Olaf; Immenschuh, Peter; Kaddu-Mulindwa, Dominic; Klausmann, Martine; Klein, Stefan; Ko, Yon-Dschun; Köchling, Georg; Koenigsmann, Michael; Kostrewa, Philippe; Kraemer, Doris Maria; Kremers, Stephan; Kropff, Martin; La Rosée, Paul; Mahlberg, Rolf; Martens, Uwe; Neise, Michael; Nückel, Holger; Pönisch, Wolfram; Procaccianti, Maria; Rafiyan, Mohammed R; Reimer, Peter; Riecke, Armin; Rummel, Mathias; Runde, Volker; Schaich, Markus; Scheid, Christoph; Schmidt-Hieber, Martin; Schmitt, Stefan; Schöndube, Daniel; Schwarzer, Andreas; Staib, Peter; Steiniger, Heike; Sturmberg, Dirk; Tischler, Hans-Joachim; Trummer, Arne; Tschechne, Barbara; Verbeek, Walter; Whitlock, Bettina; de Wit, Maike; Zaiß, Matthias; Ziske, Carsten
    Addition of isatuximab to lenalidomide, bortezomib, and dexamethasone as induction therapy for newly diagnosed, transplantation-eligible patients with multiple myeloma (GMMG-HD7) : Part 1 of an open-label, multicentre, randomised, active-controlled, phase 3 trial
    In: The Lancet Haematology Jg. 9 (2022) Nr. 11, S. e810 - e821
    ISSN: 2352-3026
    Online Volltext: dx.doi.org/
  • Xie, Xiaoqing; Frank, Daria; Patnana, Pradeep Kumar; Schütte, Judith; Al‐matary, Yahya; Liu, Longlong; Wei, Lanying; Dugas, Martin; Varghese, Julian; Nimmagadda, Subbaiah Chary; Khandanpour, Cyrus
    Curcumin as an epigenetic therapeutic agent in myelodysplastic syndromes (Mds)
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 1,
    ISSN: 1422-0067; 1661-6596
    Online Volltext: dx.doi.org/ (Open Access)
  • Ahmed, Helal Mohammed Mohammed; Nimmagadda, Subbaiah Chary; Al-Matary, Yahya S.; Fiori, Maren; May, Tobias; Frank, Daria; Patnana, Pradeep Kumar; Récher, Christian; Schliemann, Christoph; Mikesch, Jan-Henrik; Koenig, Thorsten; Rosenbauer, Frank; Hartmann, Wolfgang; Tuckermann, Jan; Dührsen, Ulrich; Lanying, Wei; Dugas, Martin; Opalka, Bertram; Lenz, Georg; Khandanpour, Cyrus
    Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells
    In: British Journal of Haematology Jg. 196 (2022) Nr. 4, S. 995 - 1006
    ISSN: 1365-2141; 0007-1048
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Longlong; Patnana, Pradeep Kumar; Xie, Xiaoqing; Frank, Daria; Nimmagadda, Subbaiah Chary; Su, Minhua; Zhang, Donghua; Koenig, Thorsten; Rosenbauer, Frank; Liebmann, Marie; Klotz, Luisa; Xu, Wendan; Vorwerk, Jan; Neumann, Felix; Hüve, Jana; Unger, Andreas; Okun, Jürgen Günther; Opalka, Bertram; Khandanpour, Cyrus
    GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia
    In: Leukemia Jg. 36 (2022) Nr. 9, S. 2196 - 2207
    ISSN: 1476-5551; 0887-6924
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Longlong; Patnana, Pradeep Kumar; Xie, Xiaoqing; Frank, Daria; Nimmagadda, Subbaiah Chary; Rosemann, Annegret; Liebmann, Marie; Klotz, Luisa; Opalka, Bertram; Khandanpour, Cyrus
    High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid Leukemia
    In: Cancers Jg. 14 (2022) Nr. 3,
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Vorwerk, Jan; Sun, Kaiyan; Frank, Daria; Neumann, Felix; Hüve, Jana; Budde, Paulina Marie; Liu, Longlong; Xie, Xiaoqing; Patnana, Pradeep Kumar; Ahmed, Helal Mohammed Mohammed; Opalka, Bertram; Lenz, Georg; Jayavelu, Ashok Kumar; Khandanpour, Cyrus
    Presence of the GFI1-36N single nucleotide polymorphism enhances the response of MLL-AF9 leukemic cells to CDK4/6 inhibition
    In: Frontiers in Oncology Jg. 12 (2022)
    ISSN: 2234-943X
    Online Volltext: dx.doi.org/ (Open Access)
  • Fraszczak, Jennifer; Vadnais, Charles; Rashkovan, Marissa; Ross, Julie; Beauchemin, Hugues; Chen, Riyan; Grapton, Damien; Khandanpour, Cyrus; Möröy, Tarik
    Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice
    In: Leukemia Jg. 33 (2019) Nr. 1, S. 110 - 121
    ISSN: 1476-5551; 0887-6924
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Vadnais, Charles; Chen, Riyan; Fraszczak, Jennifer; Yu, Zhenbao; Boulais, Jonathan; Pinder, Jordan; Frank, Daria; Khandanpour, Cyrus; Hébert, Josée; Dellaire, Graham; Côté, Jean-François; Richard, Stéphane; Orthwein, Alexandre; Drobetsky, Elliot; Möröy, Tarik
    GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.
    In: Nature Communications Jg. 9 (2018) S. 1418
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Marneth, Anna E.; Botezatu, Lacramioara; Hönes, Judith M.; Israël, Jimmy C. L.; Schütte, Judith; Vassen, Lothar; Lams, Robert F.; Bergevoet, Saskia M.; Groothuis, Laura; Mandoli, Amit; Martens, Joost H. A.; Huls, Gerwin; H.jansen, Joop; Dührsen, Ulrich; Berg, Tobias; Möröy, Tarik; Wichmann, Christian; Lo, Mia-Chia; Zhang, Dong-Er; Van Der Reijden, Bert A.; Khandanpour, Cyrus
    GFI1 is required for RUNX1/ETO positive acute myeloid leukemia
    In: Haematologica / The Hematology Journal Jg. 103 (2018) Nr. 9, S. e395 - e399
    ISSN: 1592-8721; 0390-6078
    Online Volltext: dx.doi.org/ (Open Access)
  • Thivakaran, Aniththa; Botezatu, Lacramioara; Hönes, Judith M.; Schütte, Judith; Vassen, Lothar; Al-Matary, Yahya S.; Patnana, Pradeep; Zeller, Amos; Heuser, Michael; Thol, Felicitas; Gabdoulline, Razif; Olberding, Nadine; Frank, Daria; Suslo, Marina; Köster, Renata; Lennartz, Klaus; Görgens, Andre; Giebel, Bernd; Opalka, Bertram; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi1b : A key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome
    In: Haematologica / The Hematology Journal Jg. 103 (2018) Nr. 4, S. 614 - 625
    ISSN: 1592-8721; 0390-6078
    Online Volltext: dx.doi.org/ (Open Access)
  • Hönes, Judith M.; Thivakaran, Aniththa; Botezatu, Lacramioara; Patnana, Pradeep; Castro, Symone Vitoriano da Conceição; Al-Matary, Yahya S.; Schütte, Judith; Fischer, Karen B. I.; Vassen, Lothar; Görgens, André; Dührsen, Ulrich; Giebel, Bernd; Khandanpour, Cyrus
    Enforced GFI1 expression impedes human and murine leukemic cell growth.
    In: Scientific Reports Jg. 7 (2017) S. 15720
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Thivakaran, A.; Botezatu, L.; Hönes, J.; Al-Matary, Y.; Schütte, Jochen; Patnana, P. K.; Koester, R.; Opalka, Bertram; Dührsen, Ulrich; Khandanpour, Cyrus
    GFI1B-A novel oncosuppressor which restricts number of leukemic stem stells
    In: Haematologica Jg. 102 (2017) Nr. Suppl. 2, S. 204 - 204
    ISSN: 0390-6078; 1592-8721
  • Al-Matary, Y.; Botezatu, L.; Thivakaran, A.; Köster, R.; Schütte, Jochen; Göthert, Joachim Rudolf; Dührsen, Ulrich; Opalka, Bertram; Khandanpour, Cyrus
    Growth factor independence 1 (GFI !) regulates the AML supporting function of mesenchymal stromal cells
    In: Haematologica Jg. 102 (2017) Nr. Suppl. 2, S. 459 - 459
    ISSN: 0390-6078; 1592-8721
  • Weidner, H.; Rauner, M.; Trautmann, F.; Schmitt, J.; Balaian, E.; Mies, A.; Helas, S.; Baschant, U.; Khandanpour, Cyrus; Bornhäuser, M.; Hofbauer, L.C.; Platzbecker, U.
    Myelodysplastic syndromes and bone loss in mice and men
    In: Leukemia Jg. 31 (2017) Nr. 4, S. 1003 - 1007
    ISSN: 1476-5551; 0887-6924
    Online Volltext: dx.doi.org/
  • Latteyer, Sören; Möller, Lars; Führer, Dagmar; Schmid, Kurt Werner; Pöppel, Thorsten; Khandanpour, Cyrus; Klein-Hitpaß, Ludger; Zwanziger, Denise
    A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A
    In: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 101 (2016) Nr. 3, S. 1016 - 1022
    ISSN: 0021-972X; 1945-7197
    Online Volltext: dx.doi.org/ (Open Access)
  • Al-Matary, Yahya S; Botezatu, Lacramioara; Opalka, Bertram; Hönes, Judith M; Lams, Robert F; Thivakaran, Aniththa; Schütte, Judith; Köster, Renata; Lennartz, Klaus; Schroeder, Thomas; Haas, Rainer; Dührsen, Ulrich; Khandanpour, Cyrus
    Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner
    In: Haematologica Jg. 101 (2016) Nr. 10, S. 1216 - 1227
    ISSN: 0390-6078; 1592-8721
    Online Volltext: dx.doi.org/ (Open Access)
  • Weidner, H.; Rauner, M.; Bulycheva, E.; Khandanpour, Cyrus; Bornhauser, M.; Hofbauer, L. C.; Platzbecker, U.
    Bone homeostasis is altered in a mouse model of myelodysplastic syndrome
    In: Oncology Research and treatment Jg. 39 3 (2016) S. 123 - 123
    ISSN: 2296-5270
  • Weidner, H.; Rauner, M.; Bulycheva, E.; Khandanpour, Cyrus; Bornhauser, M.; Hofbauer, L. C.; Platzbecker, U.
    Bone homeostasis is significantly altered in a myelodysplastic syndrome mouse model
    In: Haematologica Jg. 101 1 (2016) S. 493 - 493
    ISSN: 0390-6078; 1592-8721
    (Open Access)
  • Botezatu, Lacramioara; Michel, Lars C; Helness, Anne; Vadnais, Charles; Makishima, Hideki; Hönes, Judith M; Robert, François; Vassen, Lothar; Thivakaran, Aniththa; Al-Matary, Yahya; Lams, Robert F; Schütte, Judith; Giebel, Bernd; Görgens, André; Heuser, Michael; Medyouf, Hind; Maciejewski, Jaroslaw; Dührsen, Ulrich; Möröy, Tarik; Khandanpour, Cyrus
    Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML
    In: Experimental Hematology Jg. 44 (2016) Nr. 8, S. 713 - 726.e14
    ISSN: 1873-2399; 0301-472X
    Online Volltext: dx.doi.org/ (Open Access)
  • Geyh, S; Rodríguez-Paredes, M; Jäger, P; Khandanpour, Cyrus; Cadeddu, R-P; Gutekunst, J; Wilk, C M; Fenk, R; Zilkens, C; Hermsen, D; Germing, U; Kobbe, G; Lyko, F; Haas, R; Schröder, Tobias
    Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia
    In: Leukemia Jg. 30 (2016) Nr. 3, S. 683 - 691
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Hönes, J M; Botezatu, L; Helness, A; Vadnais, C; Vassen, L; Robert, F; Hergenhan, S M; Thivakaran, A; Schütte, J; Al-Matary, Y S; Lams, R F; Fraszscak, J; Makishima, H; Radivoyevitch, T; Przychodzen, B; da Conceição Castro, S V; Görgens, A; Giebel, Bernd; Klein-Hitpaß, Ludger; Lennartz, K; Heuser, M; Thiede, C; Ehninger, G; Dührsen, Ulrich; Maciejewski, J; Möröy, T; Khandanpour, Cyrus
    GFI1 as a novel prognostic and therapeutic factor for AML/MDS
    In: Leukemia Jg. 30 (2016) Nr. 6, S. 1237 - 1245
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Botezatu, Lacramioara; Michel, Lars; Makishima, Hideki; Schroeder, Thomas; Germing, Ulrich; Haas, Rainer; Van der Reijden, Bert; Marneth, Anne E.; Bergevoet, Saskia M.; Jansen, Joop H.; Przychodzen, Bartlomiej; Wlodarski, Marcin; Niemeyer, Charlotte; Platzbecker, Uwe; Ehninger, Gerhard; Unnikrishnan, Ashwin; Beck, Dominik; Pimanda, John; Hellström-Lindberg, Eva; Malcovati, Luca; Boultwood, Jacqueline; Pellagatti, Andrea; Papaemmanuil, Elli; Le Coutre, Philipp; Kaeda, Jaspal; Opalka, Bertram; Möröy, Tarik; Dührsen, Ulrich; Maciejewski, Jaroslaw; Khandanpour, Cyrus
    GFI136N as a therapeutic and prognostic marker for myelodysplastic syndrome
    In: Experimental Hematology Jg. 44 (2016) Nr. 7, S. 590 - 595.e1
    ISSN: 1873-2399; 0301-472X
    Online Volltext: dx.doi.org/ (Open Access)
  • Gassa, Asmae; Kalkavan, Halime; Jian, Fu; Duhan, Vikas; Khairnar, Vishal; Shaabani, Namir; Honke, Nadine; Carpinteiro, Alexander; Botezatu, Lacramioara; Crivello, Pietro; Dolff, Sebastian; Ferencik, Stanislav; Häussinger, Dieter; Khandanpour, Cyrus; Fleischhauer, Katharina; Witzke, Oliver; Wahlers, Thorsten; Hardt, Cornelia; Lang, Philipp A; Lang, Karl S.
    High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model
    In: Cellular Physiology and Biochemistry Jg. 38 (2016) Nr. 4, S. 1343 - 1353
    ISSN: 1015-8987; 1421-9778
    Online Volltext: dx.doi.org/ (Open Access)
  • Fraszczak, J.; Chen, R. Y.; Rashkovan, M.; Vadnais, C.; Khandanpour, Cyrus; Moroy, T.
    Low GFI1 expression level drive the development of acute myeloid leukemia and fatal myeloproliferative neoplasia by blocking differentiation and P53-mediated apoptosis
    In: Experimental Hematoloy Jg. 44 1 (2016) Nr. 9, S. 71 - S71
    ISSN: 0301-472X
    Online Volltext: dx.doi.org/
  • Fraszczak, Jennifer; Helness, Anne; Chen, Riyan; Vadnais, Charles; Robert, François; Khandanpour, Cyrus; Möröy, Tarik
    Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1
    In: PLoS ONE Jg. 11 (2016) Nr. 7, S. e0160344
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Duhan, Vikas; Khairnar, Vishal; Friedrich, Sarah-Kim; Zhou, Fan; Gassa, Asmae; Honke, Nadine; Shaabani, Namir; Gailus, Nicole; Botezatu, Lacramioara; Khandanpour, Cyrus; Dittmer, Ulf; Haüssinger, Dieter; Recher, Mike; Hardt, Cornelia; Lang, Philipp A.; Lang, Karl S.
    Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8 + T-cell priming and viral control
    In: Scientific Reports Jg. 6 (2016) S. 19191
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Khandanpour, Cyrus; Dührsen, Ulrich; Marneth, A.; Michel, L.; Ehninger, G.; Pimanda, J.; Vadnais, C.; van der Reijden, B.; Hoenes, J.; Lacramioara, B.; Radiovoyevich, T.; Unnikrishnan, A.; Schroeder, T.; Makishima, H.; Platzbecker, U.; Moroy, T.; Jansen, J.; Maciejewski, J.; Helness, A.; Papaemmanuil, E.; Germing, U.; Haas, R.
    72 personalized treatment approach for GFI 136N heterozygous or homozygous MDS patients
    In: Leukemia Research Jg. 39 (2015) Nr. Suppl. 1, S. S35
    ISSN: 1873-5835
    Online Volltext: dx.doi.org/
  • Möröy, Tarik; Vassen, Lothar; Wilkes, Brian; Khandanpour, Cyrus
    From cytopenia to leukemia : the role of Gfi1 and Gfi1b in blood formation
    In: Blood Jg. 126 (2015) Nr. 24, S. 2561 - 2569
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Monteferrario, Davide; Bolar, Nikhita A; Marneth, Anna E; Hebeda, Konnie M; Bergevoet, Saskia M; Veenstra, Hans; Laros-van Gorkom, Britta A P; MacKenzie, Marius A; Khandanpour, Cyrus; Botezatu, Lacramiora; Fransen, Erik; Van Camp, Guy; Duijnhouwer, Anthonie L; Salemink, Simone; Willemsen, Brigith; Huls, Gerwin; Preijers, Frank; Van Heerde, Waander; Jansen, Joop H; Kempers, Marlies J E; Loeys, Bart L; Van Laer, Lut; Van der Reijden, Bert A
    A dominant-negative GFI1B mutation in the gray platelet syndrome
    In: The New England Journal of Medicine Jg. 370 (2014) Nr. 3, S. 245 - 253
    ISSN: 1533-4406; 0028-4793
    Online Volltext: dx.doi.org/ (Open Access)
  • Hones, J.; Botezatu, L.; Thiede, C.; Reijden, B.; Ehninger, G.; Opalka, Bertram; Valk, P.; Lowenberg, B.; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi1 as a novel prognostic marker and tumor suppressor in acute myeloid leukemia
    In: Onkologie Jg. 36 7 (2013) S. 193 - 193
    ISSN: 0378-584X; 1423-0240
  • Khandanpour, Cyrus; Möröy, Tarik
    Gfi1 as a regulator of p53 and a therapeutic target for ALL
    In: OncoTarget Jg. 4 (2013) Nr. 3, S. 374 - 375
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/
  • Michel, Lars; Botezatu, L.; Hones, J.; Platzbecker, U.; Schroder, T.; Germing, U.; Rudolph, R.; Sengpiel, Jana; von Verschuer, U.; Grapton, D.; Ehninger, G.; Haas, R.; Moroy, T.; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi136N is a novel prognostic marker for the progression of myelodysplastic syndrome to Acute myeloid leukemia
    In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 188 - 188
    ISSN: 0378-584X; 1423-0240
  • Khandanpour, Cyrus; Phelan, James D.; Vassen, Lothar; Schütte, Judith; Chen, Riyan; Horman, Shane R.; Gaudreau, Marie-Claude; Krongold, Joseph; Zhu, Jinfang; Paul, William E.; Dührsen, Ulrich; Göttgens, Bertie; Grimes, H. Leighton; Möröy, Tarik
    Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia
    In: Cancer Cell Jg. 23 (2013) Nr. 2, S. 200 - 214
    ISSN: 1535-6108; 1878-3686
    Online Volltext: dx.doi.org/ (Open Access)
  • Khandanpour, Cyrus; Dührsen, Ulrich; Röth, Alexander
    Hand-foot syndrome : common presentation in an uncommon situation
    In: European Journal of Haematology Jg. 91 (2013) Nr. 5, S. 472
    ISSN: 1600-0609; 0902-4441; 0036-553X
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Dürig, Jan; Dührsen, Ulrich
    Leukämien : Modellkrankheiten für die Entstehung und Behandlung von Krebs
    In: Unikate: Berichte aus Forschung und Lehre (2013) Nr. 44: Medizin : 50 Jahre Universitätsklinikum Essen, S. 114 - 125
    ISBN: 978-3-934359-44-4 ISSN: 0944-6060; 1869-3881
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bjerknes, Matthew; Khandanpour, Cyrus; Möröy, Tarik; Fujiyama, Tomoyuki; Hoshino, M.; Klisch, Tiemo J.; Ding, Qian; Gan, Lin; Wang, Jiafang; Martín, Martin G.; Cheng, Hazel
    Origin of the brush cell lineage in the mouse intestinal epithelium
    In: Developmental Biology Jg. 362 (2012) Nr. 2, S. 194 - 218
    ISSN: 0012-1606; 1095-564X
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Krongold, J.; Schütte, Jochen; Bouwman, F.; Vassen, L.; Gaudreau, M. C.; Chen, R.; Calero-Nieto, F. J.; Diamanti, E.; Hannah, R.; Meyer, S. E.; Grimes, H. L.; van der Reijden, B. A.; Jansen, J. H.; Patel, C. V.; Peeters, J. K.; Löwenberg, B.; Dührsen, Ulrich; Göttgens, B.; Möröy, T.
    The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice
    In: Blood Jg. 120 (2012) Nr. 19, S. 4006 - 4017
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Möröy, Tarik; Khandanpour, Cyrus
    Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation
    In: Seminars in immunology Jg. 23 (2011) Nr. 5, S. 368 - 378
    ISSN: 1096-3618
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Kosan, Christian; Gaudreau, Marie-Claude; Dührsen, Ulrich; Hébert, Josée; Zeng, Hui; Möröy, Tarik
    Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease
    In: Stem Cells Jg. 29 (2011) Nr. 2, S. 376 - 385
    ISSN: 1549-4918; 1066-5099
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Thiede, Christian; Valk, Peter J.; Sharif-Askari, Ehssan; Nückel, Holger; Lohmann, Dietmar; Horsthemke, Bernhard; Siffert, Winfried; Neubauer, Andreas; Grzeschik, Karl-Heinz; Bloomfield, Clara D.; Marcucci, Guido; Maharry, Kati; Slovak, Marilyn L.; van der Reijden, Bert A.; Jansen, Joop H.; Schackert, Hans K.; Afshar, Khashayar; Schnittger, Susanne; Peeters, Justine K.; Kroschinsky, Frank; Ehninger, Gerhard; Lowenberg, Bob; Dührsen, Ulrich; Möröy, Tarik
    A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia
    In: Blood Jg. 115 (2010) Nr. 12, S. 2462 - 2472
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Möröy, Tarik; Kosan, Christian; Okayama, Taro; Paul, William E.; Sharif-Askari, Ehssan; Vassen, Lothar; Gaudreau, Marie-Claude; Zhu, Jinfang
    Evidence that Growth factor independence 1b (Gfi1b) regulates dormancy and peripheral blood mobilization of hematopoietic stem cells
    In: Blood Jg. 116 (2010) Nr. 24, S. 5149 - 5161
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Sharif-Askari, Ehssan; Möröy, Tarik; Zeng, Hui; Jin, Jianmin; Okayama, Taro; Heyd, Florian; Gaudreau, Marie-Claude; Khandanpour, Cyrus; Kosan, Christian; Vassen, Lothar
    Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65
    In: Molecular and Cellular Biology (MCB) Jg. 30 (2010) Nr. 16, S. 3929 - 3942
    ISSN: 1098-5549; 0270-7306
    Online Volltext: dx.doi.org/
  • Vassen, Lothar; Möröy, Tarik; Dührsen, Ulrich; Mahlmann, Stefan; Jansen, Joop H.; van der Reijden, Bert A.; Ebeling, Peter; Khandanpour, Cyrus
    Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia
    In: International Journal of Hematology Jg. 89 (2009) Nr. 4, S. 422 - 430
    ISSN: 1865-3774
    Online Volltext: dx.doi.org/
  • Igwe, Ignatius Emeka; Möröy, Tarik; Brüne, Bernhard; Sharif-Askari, Ehssan; Khandanpour, Cyrus; Kosan, Christian
    The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Iγ2b germline transcripts
    In: European Journal of Immunology Jg. 38 (2008) Nr. 11, S. 2916 - 3244
    ISSN: 1521-4141; 0014-2980
    Online Volltext: dx.doi.org/

    • Abstracts

  • Eisfeld, C.; Kajüter, H.; Möller, L.; Oesterling, F.; Khandanpour, Cyrus; Stang, Andreas;
    Entwicklungen im Überleben beim Multiplen Myelom : eine Analyse des Krebsregisters NRW
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 85 - 86
    ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X
    Online Volltext: dx.doi.org/ (Open Access)
  • Goldschmidt, Hartmut; Mai, Elias K; Nievergall, Eva; Fenk, Roland; Bertsch, Uta; Tichy, Diana; Besemer, Britta; Dürig, Jan; Schroers, Roland; Metzler, Ivana v.; Haenel, Mathias; Mann, Christoph; Asemissen, Anne-Marie; Heilmeier, Bernhard; Huhn, Stefanie; Kriegsmann, Katharina; Weinhold, Niels; Luntz, Steffen P.; Holderried, Tobias A. W.; Trautmann-Grill, Karolin; Gezer, Deniz; Klaiber-Hakimi, Maika; Mueller, Martin; Khandanpour, Cyrus; Knauf, Wolfgang; Munder, Markus; Geer, Thomas; Riesenberg, Hendrik; Thomalla, Joerg; Hoffmann, Martin; Raab, Marc-Steffen; Salwender, Hans; Weisel, Katja;
    Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients : The Phase III GMMG-HD7 Trial
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 463 - 465
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/ (Open Access)
  • Noman, Helal Mohammed Mohammed Ahmed; Al-Matary, Yahya Saleh; Nimmagadda, Subbaiah Chary; Patnana, Pradeep Kumar; Liu, Longlong; Wei, Lanying; Frank, Daria; Lenz, Georg; Khandanpour, Cyrus;
    Leukaemia Cells Induced Metabolic Alterations in AML Associated Mesenchymal Stem Cells Via Notch Signalling
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 4347 - 4348
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/ (Open Access)
  • Patnana, Pradeep Kumar; Behrens, M.; Klotz, L.; Liebmann, M.; Frank, D.; Nimmagadda, C.; Siveke, Jens; Trajkovic-Arsic, Marija; Hanenberg, Helmut; Thivakaran, Aniththa; Khandanpour, Cyrus;
    Growth factor independence 1 expression induced metabolic vulnerabilities and presents novel therapeutic opportunities in acute myeloid leukemia
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 43 - 44
    ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X
    Online Volltext: dx.doi.org/ (Open Access)
  • Heinrichs, D.; Schütte, Jochen; Thivakaran, A.; Al-Matary, Y.; Suslo, M.; Dührsen, U.; Khandanpour, Cyrus;
    Curcumin as a treatment approach for MDS/AML in human
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 76
    ISSN: 2296-5262; 2296-5270
    Online Volltext: dx.doi.org/ (Open Access)
  • Fiori, M. N.; Al-Matary, Y.; Fraszczak, J.; Heinrichs, D.; Opalka, Bertram; Dührsen, U.; Möröy, T.; Khandanpour, Cyrus;
    The bone marrow niche as a potential target to improve the outcome of acute myeoloid leukemia using dexamethasone
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 73 - 74
    ISSN: 2296-5262; 2296-5270
    Online Volltext: dx.doi.org/ (Open Access)
  • Phelan, James D.; Khandanpour, Cyrus; Horman, Shane; Gaudreau, Marie-Claude; Zhu, Jinfang; Paul, William E.; Dührsen, Ulrich; Grimes, H. Leighton; Moroy, Tarik
    Growth Factor Independent-1 (Gfi1) Is Critically Required for T-Cell Acute Lymphoblastic Leukemia (T-ALL) Tumor Initiation and Maintenance
    In: Blood Jg. 116 (2010) Nr. 21, S. 1299
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/

    • Bücher/Sammelwerke/Tagungsbände

  • Khandanpour, Cyrus
    Funktion der Transkriptonsfaktoren Gfi1 und Gfi1b in der physiologischen und malignen Entwicklung des hämatopoetischen Systems
    Duisburg ; Essen (2017) 1 CD-ROM

    • Dissertation

  • Khandanpour, Cyrus;
    Affinitätschromatographie mit orientiert und nicht-orientiert immobilisiertem Calmodulin am Beispiel der Aufreinigung der Ubiquityl-Calmodulin-Synthetase Faktor 2
    Duisburg-Essen (2005) 99 Bl. : Ill., graph. Darst.
    Online Volltext