Personensuche

Personensuche

Bitte geben Sie den Namen der gesuchten Person ein.

Es wurde 1 Person gefunden.

Cyrus Khandanpour

Funktionen

  • , Zentrum für Innere Medizin

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Vorwerk, Jan; Liu, Longlong; Stadler, Theresa Helene; Frank, Daria; Ahmed, Helal Mohammed Mohammed; Patnana, Pradeep Kumar; Kebenko, Maxim; Dazert, Eva; Opalka, Bertram; von Bubnoff, Nikolas; Khandanpour, Cyrus
    Germline Single-Nucleotide Polymorphism GFI1-36N Causes Alterations in Mitochondrial Metabolism and Leads to Increased ROS-Mediated DNA Damage in a Murine Model of Human Acute Myeloid Leukemia
    In: Biomedicines Jg. 13 (2025) Nr. 1, 107
    Online Volltext: dx.doi.org/ (Open Access)
  • Merz, Maximilian; Albici, Anca-Maria; von Tresckow, Bastian; Rathje, Kristin; Fenk, Roland; Holderried, Tobias; Müller, Fabian; Tovar, Natalia; Oliver-Cáldes, Aina; Vucinic, Vladan; Kharboutli, Soraya; Bärmann, Ben-Niklas; Ayuk, Francis; Platzbecker, Uwe; Stölzel, Friedrich; Schub, Nathalie; Schmitz, Friederike; Fandrei, David; Born, Patrick; Khandanpour, Cyrus; Hanoun, Christine; Hörster, Keven; Teichert, Marcel; Jeker, Barbara; Hoffmann, Michele; Kröger, Nicolaus; de Larrea, Carlos Fernández; Pabst, Thomas; Gagelmann, Nico
    Idecabtagene vicleucel or ciltacabtagene autoleucel for relapsed or refractory multiple myeloma : An international multicenter study
    In: HemaSphere: Open Access Journal of the European Hematology Association Jg. 9 (2025) Nr. 1, e70070
    Online Volltext: dx.doi.org/ (Open Access)
  • Merz, Maximilian; Dima, Danai; Hashmi, Hamza; Ahmed, Nausheen; Stölzel, Friedrich; Holderried, Tobias A. W.; Fenk, Roland; Müller, Fabian; Tovar, Natalia; Oliver-Cáldes, Aina; Rathje, Kristin; Davis, James A.; Fandrei, David; Vucinic, Vladan; Kharboutli, Soraya; Baermann, Ben-Niklas; Ayuk, Francis; Platzbecker, Uwe; Albici, Anca-Maria; Schub, Nathalie; Schmitz, Friederike; Shune, Leyla; Khouri, Jack; Anwer, Faiz; Raza, Shahzad; McGuirk, Joseph; Mahmoudjafari, Zahra; Green, Kimberly; Khandanpour, Cyrus; Teichert, Marcel; Jeker, Barbara; Hoffmann, Michele; Kröger, Nicolaus; von Tresckow, Bastian; de Larrea, Carlos Fernández; Pabst, Thomas; Abdallah, Al-Ola; Gagelmann, Nico
    Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy
    In: Blood Cancer Journal Jg. 14 (2024) Nr. 1, 214
    Online Volltext: dx.doi.org/ (Open Access)
  • Kamili, Abdulaziz; Ahmadi, Paymon; Leypoldt, Lisa; Marquard, Franziska; Schaefers, Christoph; Kosch, Ricardo; Peters, Frederik; Kusche, Henrik; Zamrik, Tanja; Hanoun, Christine; Seib, Maximilian; Shumilov, Evgenii; Leitner, Theo; Khandanpour, Cyrus; Bokemeyer, Carsten; Weisel, Katja; Ghandili, Susanne
    Multiple myeloma in the young : Insights on prognosis, clinical features and treatment outcome derived from nationwide German registry data and a nested multicenter sample
    In: Haematologica / The Hematology Journal Jg. 109 (2024) Nr. 11, S. 3795 - 3799
    Online Volltext: dx.doi.org/ (Open Access)
  • Sun, Kaiyan; Jin, Ling; Karolová, Jana; Vorwerk, Jan; Hailfinger, Stephan; Opalka, Bertram; Zapukhlyak, Myroslav; Lenz, Georg; Khandanpour, Cyrus
    Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma
    In: Cancers Jg. 15 (2023) Nr. 8, 2373
    Online Volltext: dx.doi.org/ (Open Access)
  • Xie, Xiaoqing; Patnana, Pradeep Kumar; Frank, Daria; Schütte, Judith; Al-Matary, Yahya; Künstner, Axel; Busch, Hauke; Ahmed, Helal; Liu, Longlong; Engel, Daniel Robert; Dührsen, Ulrich; Rosenbauer, Frank; Von Bubnoff, Nikolas; Lenz, Georg; Khandanpour, Cyrus
    Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs
    In: Frontiers in Cell and Developmental Biology Jg. 11 (2023) 866847
    Online Volltext: dx.doi.org/ (Open Access)
  • Patnana, Pradeep Kumar; Liu, Longlong; Frank, Daria; Nimmagadda, Subbaiah Chary; Behrens, Matthias; Ahmed, Helal; Xie, Xiaoqing; Liebmann, Marie; Wei, Lanying; Gerdemann, Andrea; Thivakaran, Aniththa; Humpf, Hans-Ulrich; Klotz, Luisa; Dugas, Martin; Varghese, Julian; Trajkovic-Arsic, Marija; Siveke, Jens; Hanenberg, Helmut; Opalka, Bertram; Dührsen, Ulrich; Reinhardt, Hans Christian; Guenther, Ulrich; von Bubnoff, Nikolas; Khandanpour, Cyrus
    Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cells
    In: British Journal of Haematology Jg. 202 (2023) Nr. 5, S. 1033 - 1048
    Online Volltext: dx.doi.org/ (Open Access)
  • Frank, Daria; Patnana, Pradeep Kumar; Vorwerk, Jan; Mao, Lianghao; Gopal, Lavanya Mokada; Jung, Noelle; Hennig, Thorben; Ruhnke, Leo; Frenz, Joris Maximillian; Kuppusamy, Maithreyan; Autry, Robert; Wei, Lanying; Sun, Kaiyan; Mohammed Ahmed, Helal Mohammed; Künstner, Axel; Busch, Hauke; Müller, Heiko; Hutter, Stephan; Hoermann, Gregor; Liu, Longlong; Xie, Xiaoqing; Al-Matary, Yahya; Nimmagadda, Subbaiah Chary; Charles Cano, Fiorella; Heuser, Michael; Thol, Felicitas; Göhring, Gudrun; Steinemann, Doris; Thomale, Jürgen; Leitner, Theo; Fischer, Anja; Rad, Roland; Röllig, Christoph; Altmann, Heidi; Kunadt, Desiree; Berdel, Wolfgang E.; Hüve, Jana; Neumann, Felix; Klingauf, Jürgen; Calderon, Virginie; Opalka, Bertram; Dührsen, Ulrich; Rosenbauer, Frank; Dugas, Martin; Varghese, Julian; Reinhardt, Hans Christian; von Bubnoff, Nikolas; Möröy, Tarik; Lenz, Georg; Batcha, Aarif M. N.; Giorgi, Marianna; Selvam, Murugan; Wang, Eunice; McWeeney, Shannon K.; Tyner, Jeffrey W.; Stölzel, Friedrich; Mann, Matthias; Jayavelu, Ashok Kumar; Khandanpour, Cyrus
    Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy
    In: Blood Jg. 142 (2023) Nr. 25, S. 2175 - 2191
    Online Volltext: dx.doi.org/ (Open Access)
  • Goldschmidt, Hartmut; Mai, Elias K.; Bertsch, Uta; Fenk, Roland; Nievergall, Eva; Tichy, Diana; Besemer, Britta; Dürig, Jan; Schroers, Roland; von Metzler, Ivana; Hänel, Mathias; Mann, Christoph; Asemissen, Anne M.; Heilmeier, Bernhard; Weinhold, Niels; Huhn, Stefanie; Kriegsmann, Katharina; Luntz, Steffen P.; Holderried, Tobias A W; Trautmann-Grill, Karolin; Gezer, Deniz; Klaiber-Hakimi, Maika; Müller, Martin; Khandanpour, Cyrus; Knauf, Wolfgang; Scheid, Christof; Munder, Markus; Geer, Thomas; Riesenberg, Hendrik; Thomalla, Jörg; Hoffmann, Martin; Raab, Marc S.; Salwender, Hans J.; Weisel, Katja C.; Ziske, Carsten;
    ; ; German-Speaking Myeloma Multicenter Group (GMMG) HD7 investigators (Hrsg.)
    Addition of isatuximab to lenalidomide, bortezomib, and dexamethasone as induction therapy for newly diagnosed, transplantation-eligible patients with multiple myeloma (GMMG-HD7) : Part 1 of an open-label, multicentre, randomised, active-controlled, phase 3 trial
    In: The Lancet Haematology Jg. 9 (2022) Nr. 11, S. e810 - e821
    Online Volltext: dx.doi.org/
  • Xie, Xiaoqing; Frank, Daria; Patnana, Pradeep Kumar; Schütte, Judith; Al‐matary, Yahya; Liu, Longlong; Wei, Lanying; Dugas, Martin; Varghese, Julian; Nimmagadda, Subbaiah Chary; Khandanpour, Cyrus
    Curcumin as an epigenetic therapeutic agent in myelodysplastic syndromes (Mds)
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 1, 411
    Online Volltext: dx.doi.org/ (Open Access)
  • Ahmed, Helal Mohammed Mohammed; Nimmagadda, Subbaiah Chary; Al-Matary, Yahya S.; Fiori, Maren; May, Tobias; Frank, Daria; Patnana, Pradeep Kumar; Récher, Christian; Schliemann, Christoph; Mikesch, Jan-Henrik; Koenig, Thorsten; Rosenbauer, Frank; Hartmann, Wolfgang; Tuckermann, Jan; Dührsen, Ulrich; Lanying, Wei; Dugas, Martin; Opalka, Bertram; Lenz, Georg; Khandanpour, Cyrus
    Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells
    In: British Journal of Haematology Jg. 196 (2022) Nr. 4, S. 995 - 1006
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Longlong; Patnana, Pradeep Kumar; Xie, Xiaoqing; Frank, Daria; Nimmagadda, Subbaiah Chary; Su, Minhua; Zhang, Donghua; Koenig, Thorsten; Rosenbauer, Frank; Liebmann, Marie; Klotz, Luisa; Xu, Wendan; Vorwerk, Jan; Neumann, Felix; Hüve, Jana; Unger, Andreas; Okun, Jürgen Günther; Opalka, Bertram; Khandanpour, Cyrus
    GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia
    In: Leukemia Jg. 36 (2022) Nr. 9, S. 2196 - 2207
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Longlong; Patnana, Pradeep Kumar; Xie, Xiaoqing; Frank, Daria; Nimmagadda, Subbaiah Chary; Rosemann, Annegret; Liebmann, Marie; Klotz, Luisa; Opalka, Bertram; Khandanpour, Cyrus
    High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid Leukemia
    In: Cancers Jg. 14 (2022) Nr. 3, 486
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Vorwerk, Jan; Sun, Kaiyan; Frank, Daria; Neumann, Felix; Hüve, Jana; Budde, Paulina Marie; Liu, Longlong; Xie, Xiaoqing; Patnana, Pradeep Kumar; Ahmed, Helal Mohammed Mohammed; Opalka, Bertram; Lenz, Georg; Jayavelu, Ashok Kumar; Khandanpour, Cyrus
    Presence of the GFI1-36N single nucleotide polymorphism enhances the response of MLL-AF9 leukemic cells to CDK4/6 inhibition
    In: Frontiers in Oncology Jg. 12 (2022) 903691
    Online Volltext: dx.doi.org/ (Open Access)
  • Fraszczak, Jennifer; Vadnais, Charles; Rashkovan, Marissa; Ross, Julie; Beauchemin, Hugues; Chen, Riyan; Grapton, Damien; Khandanpour, Cyrus; Möröy, Tarik
    Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice
    In: Leukemia Jg. 33 (2019) Nr. 1, S. 110 - 121
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Vadnais, Charles; Chen, Riyan; Fraszczak, Jennifer; Yu, Zhenbao; Boulais, Jonathan; Pinder, Jordan; Frank, Daria; Khandanpour, Cyrus; Hébert, Josée; Dellaire, Graham; Côté, Jean-François; Richard, Stéphane; Orthwein, Alexandre; Drobetsky, Elliot; Möröy, Tarik
    GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.
    In: Nature Communications Jg. 9 (2018) S. 1418
    Online Volltext: dx.doi.org/ (Open Access)
  • Marneth, Anna E.; Botezatu, Lacramioara; Hönes, Judith M.; Israël, Jimmy C. L.; Schütte, Judith; Vassen, Lothar; Lams, Robert F.; Bergevoet, Saskia M.; Groothuis, Laura; Mandoli, Amit; Martens, Joost H. A.; Huls, Gerwin; H.jansen, Joop; Dührsen, Ulrich; Berg, Tobias; Möröy, Tarik; Wichmann, Christian; Lo, Mia-Chia; Zhang, Dong-Er; Van Der Reijden, Bert A.; Khandanpour, Cyrus
    GFI1 is required for RUNX1/ETO positive acute myeloid leukemia
    In: Haematologica / The Hematology Journal Jg. 103 (2018) Nr. 9, S. e395 - e399
    Online Volltext: dx.doi.org/ (Open Access)
  • Thivakaran, Aniththa; Botezatu, Lacramioara; Hönes, Judith M.; Schütte, Judith; Vassen, Lothar; Al-Matary, Yahya S.; Patnana, Pradeep; Zeller, Amos; Heuser, Michael; Thol, Felicitas; Gabdoulline, Razif; Olberding, Nadine; Frank, Daria; Suslo, Marina; Köster, Renata; Lennartz, Klaus; Görgens, Andre; Giebel, Bernd; Opalka, Bertram; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi1b : A key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome
    In: Haematologica / The Hematology Journal Jg. 103 (2018) Nr. 4, S. 614 - 625
    Online Volltext: dx.doi.org/ (Open Access)
  • Hönes, Judith M.; Thivakaran, Aniththa; Botezatu, Lacramioara; Patnana, Pradeep; Castro, Symone Vitoriano da Conceição; Al-Matary, Yahya S.; Schütte, Judith; Fischer, Karen B. I.; Vassen, Lothar; Görgens, André; Dührsen, Ulrich; Giebel, Bernd; Khandanpour, Cyrus
    Enforced GFI1 expression impedes human and murine leukemic cell growth.
    In: Scientific Reports Jg. 7 (2017) S. 15720
    Online Volltext: dx.doi.org/ (Open Access)
  • Thivakaran, A.; Botezatu, L.; Hönes, J.; Al-Matary, Y.; Schütte, Jochen; Patnana, P. K.; Koester, R.; Opalka, Bertram; Dührsen, Ulrich; Khandanpour, Cyrus
    GFI1B-A novel oncosuppressor which restricts number of leukemic stem stells
    In: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. Suppl. 2, S. 204 - 204
  • Al-Matary, Y.; Botezatu, L.; Thivakaran, A.; Köster, R.; Schütte, Jochen; Göthert, Joachim Rudolf; Dührsen, Ulrich; Opalka, Bertram; Khandanpour, Cyrus
    Growth factor independence 1 (GFI !) regulates the AML supporting function of mesenchymal stromal cells
    In: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. Suppl. 2, S. 459 - 459
  • Weidner, H.; Rauner, M.; Trautmann, F.; Schmitt, J.; Balaian, E.; Mies, A.; Helas, S.; Baschant, U.; Khandanpour, Cyrus; Bornhäuser, M.; Hofbauer, L.C.; Platzbecker, U.
    Myelodysplastic syndromes and bone loss in mice and men
    In: Leukemia Jg. 31 (2017) Nr. 4, S. 1003 - 1007
    Online Volltext: dx.doi.org/
  • Latteyer, Sören; Möller, Lars; Führer, Dagmar; Schmid, Kurt Werner; Pöppel, Thorsten; Khandanpour, Cyrus; Klein-Hitpaß, Ludger; Zwanziger, Denise
    A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A
    In: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 101 (2016) Nr. 3, S. 1016 - 1022
    Online Volltext: dx.doi.org/ (Open Access)
  • Al-Matary, Yahya S; Botezatu, Lacramioara; Opalka, Bertram; Hönes, Judith M; Lams, Robert F; Thivakaran, Aniththa; Schütte, Judith; Köster, Renata; Lennartz, Klaus; Schroeder, Thomas; Haas, Rainer; Dührsen, Ulrich; Khandanpour, Cyrus
    Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner
    In: Haematologica / The Hematology Journal Jg. 101 (2016) Nr. 10, S. 1216 - 1227
    Online Volltext: dx.doi.org/ (Open Access)
  • Weidner, H.; Rauner, M.; Bulycheva, E.; Khandanpour, Cyrus; Bornhauser, M.; Hofbauer, L. C.; Platzbecker, U.
    Bone homeostasis is altered in a mouse model of myelodysplastic syndrome
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 123 - 123
  • Weidner, H.; Rauner, M.; Bulycheva, E.; Khandanpour, Cyrus; Bornhauser, M.; Hofbauer, L. C.; Platzbecker, U.
    Bone homeostasis is significantly altered in a myelodysplastic syndrome mouse model
    In: Haematologica / The Hematology Journal Jg. 101 1 (2016) S. 493 - 493
    (Open Access)
  • Botezatu, Lacramioara; Michel, Lars C; Helness, Anne; Vadnais, Charles; Makishima, Hideki; Hönes, Judith M; Robert, François; Vassen, Lothar; Thivakaran, Aniththa; Al-Matary, Yahya; Lams, Robert F; Schütte, Judith; Giebel, Bernd; Görgens, André; Heuser, Michael; Medyouf, Hind; Maciejewski, Jaroslaw; Dührsen, Ulrich; Möröy, Tarik; Khandanpour, Cyrus
    Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML
    In: Experimental Hematology Jg. 44 (2016) Nr. 8, S. 713 - 726.e14
    Online Volltext: dx.doi.org/ (Open Access)
  • Geyh, S; Rodríguez-Paredes, M; Jäger, P; Khandanpour, Cyrus; Cadeddu, R-P; Gutekunst, J; Wilk, C M; Fenk, R; Zilkens, C; Hermsen, D; Germing, U; Kobbe, G; Lyko, F; Haas, R; Schröder, Tobias
    Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia
    In: Leukemia Jg. 30 (2016) Nr. 3, S. 683 - 691
    Online Volltext: dx.doi.org/
  • Hönes, J M; Botezatu, L; Helness, A; Vadnais, C; Vassen, L; Robert, F; Hergenhan, S M; Thivakaran, A; Schütte, J; Al-Matary, Y S; Lams, R F; Fraszscak, J; Makishima, H; Radivoyevitch, T; Przychodzen, B; da Conceição Castro, S V; Görgens, A; Giebel, Bernd; Klein-Hitpaß, Ludger; Lennartz, K; Heuser, M; Thiede, C; Ehninger, G; Dührsen, Ulrich; Maciejewski, J; Möröy, T; Khandanpour, Cyrus
    GFI1 as a novel prognostic and therapeutic factor for AML/MDS
    In: Leukemia Jg. 30 (2016) Nr. 6, S. 1237 - 1245
    Online Volltext: dx.doi.org/
  • Botezatu, Lacramioara; Michel, Lars; Makishima, Hideki; Schroeder, Thomas; Germing, Ulrich; Haas, Rainer; Van der Reijden, Bert; Marneth, Anne E.; Bergevoet, Saskia M.; Jansen, Joop H.; Przychodzen, Bartlomiej; Wlodarski, Marcin; Niemeyer, Charlotte; Platzbecker, Uwe; Ehninger, Gerhard; Unnikrishnan, Ashwin; Beck, Dominik; Pimanda, John; Hellström-Lindberg, Eva; Malcovati, Luca; Boultwood, Jacqueline; Pellagatti, Andrea; Papaemmanuil, Elli; Le Coutre, Philipp; Kaeda, Jaspal; Opalka, Bertram; Möröy, Tarik; Dührsen, Ulrich; Maciejewski, Jaroslaw; Khandanpour, Cyrus
    GFI136N as a therapeutic and prognostic marker for myelodysplastic syndrome
    In: Experimental Hematology Jg. 44 (2016) Nr. 7, S. 590 - 595.e1
    Online Volltext: dx.doi.org/ (Open Access)
  • Gassa, Asmae; Kalkavan, Halime; Jian, Fu; Duhan, Vikas; Khairnar, Vishal; Shaabani, Namir; Honke, Nadine; Carpinteiro, Alexander; Botezatu, Lacramioara; Crivello, Pietro; Dolff, Sebastian; Ferencik, Stanislav; Häussinger, Dieter; Khandanpour, Cyrus; Fleischhauer, Katharina; Witzke, Oliver; Wahlers, Thorsten; Hardt, Cornelia; Lang, Philipp A; Lang, Karl S.
    High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model
    In: Cellular Physiology and Biochemistry Jg. 38 (2016) Nr. 4, S. 1343 - 1353
    Online Volltext: dx.doi.org/ (Open Access)
  • Fraszczak, J.; Chen, R. Y.; Rashkovan, M.; Vadnais, C.; Khandanpour, Cyrus; Moroy, T.
    Low GFI1 expression level drive the development of acute myeloid leukemia and fatal myeloproliferative neoplasia by blocking differentiation and P53-mediated apoptosis
    In: Experimental Hematology Jg. 44 1 (2016) Nr. 9, S. 71 - S71
    Online Volltext: dx.doi.org/
  • Fraszczak, Jennifer; Helness, Anne; Chen, Riyan; Vadnais, Charles; Robert, François; Khandanpour, Cyrus; Möröy, Tarik
    Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1
    In: PLoS ONE Jg. 11 (2016) Nr. 7, S. e0160344
    Online Volltext: dx.doi.org/ (Open Access)
  • Duhan, Vikas; Khairnar, Vishal; Friedrich, Sarah-Kim; Zhou, Fan; Gassa, Asmae; Honke, Nadine; Shaabani, Namir; Gailus, Nicole; Botezatu, Lacramioara; Khandanpour, Cyrus; Dittmer, Ulf; Haüssinger, Dieter; Recher, Mike; Hardt, Cornelia; Lang, Philipp A.; Lang, Karl S.
    Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8 + T-cell priming and viral control
    In: Scientific Reports Jg. 6 (2016) 19191
    Online Volltext: dx.doi.org/ (Open Access)
  • Khandanpour, Cyrus; Dührsen, Ulrich; Marneth, A.; Michel, L.; Ehninger, G.; Pimanda, J.; Vadnais, C.; van der Reijden, B.; Hoenes, J.; Lacramioara, B.; Radiovoyevich, T.; Unnikrishnan, A.; Schroeder, T.; Makishima, H.; Platzbecker, U.; Moroy, T.; Jansen, J.; Maciejewski, J.; Helness, A.; Papaemmanuil, E.; Germing, U.; Haas, R.
    72 personalized treatment approach for GFI 136N heterozygous or homozygous MDS patients
    In: Leukemia Research Jg. 39 (2015) Nr. Suppl. 1, S. S35
    Online Volltext: dx.doi.org/
  • Möröy, Tarik; Vassen, Lothar; Wilkes, Brian; Khandanpour, Cyrus
    From cytopenia to leukemia : the role of Gfi1 and Gfi1b in blood formation
    In: Blood Jg. 126 (2015) Nr. 24, S. 2561 - 2569
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Monteferrario, Davide; Bolar, Nikhita A; Marneth, Anna E; Hebeda, Konnie M; Bergevoet, Saskia M; Veenstra, Hans; Laros-van Gorkom, Britta A P; MacKenzie, Marius A; Khandanpour, Cyrus; Botezatu, Lacramiora; Fransen, Erik; Van Camp, Guy; Duijnhouwer, Anthonie L; Salemink, Simone; Willemsen, Brigith; Huls, Gerwin; Preijers, Frank; Van Heerde, Waander; Jansen, Joop H; Kempers, Marlies J E; Loeys, Bart L; Van Laer, Lut; Van der Reijden, Bert A
    A dominant-negative GFI1B mutation in the gray platelet syndrome
    In: The New England Journal of Medicine Jg. 370 (2014) Nr. 3, S. 245 - 253
    Online Volltext: dx.doi.org/ (Open Access)
  • Hones, J.; Botezatu, L.; Thiede, C.; Reijden, B.; Ehninger, G.; Opalka, Bertram; Valk, P.; Lowenberg, B.; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi1 as a novel prognostic marker and tumor suppressor in acute myeloid leukemia
    In: Onkologie Jg. 36 7 (2013) S. 193 - 193
  • Khandanpour, Cyrus; Möröy, Tarik
    Gfi1 as a regulator of p53 and a therapeutic target for ALL
    In: OncoTarget Jg. 4 (2013) Nr. 3, S. 374 - 375
    Online Volltext: dx.doi.org/
  • Michel, Lars; Botezatu, L.; Hones, J.; Platzbecker, U.; Schroder, T.; Germing, U.; Rudolph, R.; Sengpiel, Jana; von Verschuer, U.; Grapton, D.; Ehninger, G.; Haas, R.; Moroy, T.; Dührsen, Ulrich; Khandanpour, Cyrus
    Gfi136N is a novel prognostic marker for the progression of myelodysplastic syndrome to Acute myeloid leukemia
    In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 188 - 188
  • Khandanpour, Cyrus; Phelan, James D.; Vassen, Lothar; Schütte, Judith; Chen, Riyan; Horman, Shane R.; Gaudreau, Marie-Claude; Krongold, Joseph; Zhu, Jinfang; Paul, William E.; Dührsen, Ulrich; Göttgens, Bertie; Grimes, H. Leighton; Möröy, Tarik
    Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia
    In: Cancer Cell Jg. 23 (2013) Nr. 2, S. 200 - 214
    Online Volltext: dx.doi.org/ (Open Access)
  • Khandanpour, Cyrus; Dührsen, Ulrich; Röth, Alexander
    Hand-foot syndrome : common presentation in an uncommon situation
    In: European Journal of Haematology Jg. 91 (2013) Nr. 5, S. 472
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Dürig, Jan; Dührsen, Ulrich
    Leukämien : Modellkrankheiten für die Entstehung und Behandlung von Krebs
    In: Unikate: Berichte aus Forschung und Lehre (2013) Nr. 44: Medizin : 50 Jahre Universitätsklinikum Essen, S. 114 - 125
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bjerknes, Matthew; Khandanpour, Cyrus; Möröy, Tarik; Fujiyama, Tomoyuki; Hoshino, M.; Klisch, Tiemo J.; Ding, Qian; Gan, Lin; Wang, Jiafang; Martín, Martin G.; Cheng, Hazel
    Origin of the brush cell lineage in the mouse intestinal epithelium
    In: Developmental Biology Jg. 362 (2012) Nr. 2, S. 194 - 218
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Krongold, J.; Schütte, Jochen; Bouwman, F.; Vassen, L.; Gaudreau, M. C.; Chen, R.; Calero-Nieto, F. J.; Diamanti, E.; Hannah, R.; Meyer, S. E.; Grimes, H. L.; van der Reijden, B. A.; Jansen, J. H.; Patel, C. V.; Peeters, J. K.; Löwenberg, B.; Dührsen, Ulrich; Göttgens, B.; Möröy, T.
    The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice
    In: Blood Jg. 120 (2012) Nr. 19, S. 4006 - 4017
    Online Volltext: dx.doi.org/
  • Möröy, Tarik; Khandanpour, Cyrus
    Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation
    In: Seminars in Immunology Jg. 23 (2011) Nr. 5, S. 368 - 378
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Kosan, Christian; Gaudreau, Marie-Claude; Dührsen, Ulrich; Hébert, Josée; Zeng, Hui; Möröy, Tarik
    Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease
    In: Stem Cells Jg. 29 (2011) Nr. 2, S. 376 - 385
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Thiede, Christian; Valk, Peter J.; Sharif-Askari, Ehssan; Nückel, Holger; Lohmann, Dietmar; Horsthemke, Bernhard; Siffert, Winfried; Neubauer, Andreas; Grzeschik, Karl-Heinz; Bloomfield, Clara D.; Marcucci, Guido; Maharry, Kati; Slovak, Marilyn L.; van der Reijden, Bert A.; Jansen, Joop H.; Schackert, Hans K.; Afshar, Khashayar; Schnittger, Susanne; Peeters, Justine K.; Kroschinsky, Frank; Ehninger, Gerhard; Lowenberg, Bob; Dührsen, Ulrich; Möröy, Tarik
    A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia
    In: Blood Jg. 115 (2010) Nr. 12, S. 2462 - 2472
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Möröy, Tarik; Kosan, Christian; Okayama, Taro; Paul, William E.; Sharif-Askari, Ehssan; Vassen, Lothar; Gaudreau, Marie-Claude; Zhu, Jinfang
    Evidence that Growth factor independence 1b (Gfi1b) regulates dormancy and peripheral blood mobilization of hematopoietic stem cells
    In: Blood Jg. 116 (2010) Nr. 24, S. 5149 - 5161
    Online Volltext: dx.doi.org/
  • Sharif-Askari, Ehssan; Möröy, Tarik; Zeng, Hui; Jin, Jianmin; Okayama, Taro; Heyd, Florian; Gaudreau, Marie-Claude; Khandanpour, Cyrus; Kosan, Christian; Vassen, Lothar
    Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65
    In: Molecular and Cellular Biology (MCB) Jg. 30 (2010) Nr. 16, S. 3929 - 3942
    Online Volltext: dx.doi.org/
  • Vassen, Lothar; Möröy, Tarik; Dührsen, Ulrich; Mahlmann, Stefan; Jansen, Joop H.; van der Reijden, Bert A.; Ebeling, Peter; Khandanpour, Cyrus
    Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia
    In: International Journal of Hematology Jg. 89 (2009) Nr. 4, S. 422 - 430
    Online Volltext: dx.doi.org/
  • Igwe, Ignatius Emeka; Möröy, Tarik; Brüne, Bernhard; Sharif-Askari, Ehssan; Khandanpour, Cyrus; Kosan, Christian
    The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Iγ2b germline transcripts
    In: European Journal of Immunology Jg. 38 (2008) Nr. 11, S. 2916 - 3244
    Online Volltext: dx.doi.org/

    • Abstracts

  • Patnana, P. K.; Frank, D.; Vorwerk, J.; Khandanpour, Cyrus; et al.;
    Germline variant GFI1-36N affects DNA repair in AML cells resulting in sensitivity to DNA damage and repair therapy
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 135
    Online Volltext: dx.doi.org/ (Open Access)
  • Patnana, P. K.; Behrens, M.; Ahmed, H.; Nimmagadda, S. C.; von Bubnoff, N.; Khandanpour, Cyrus;
    Growth factor independence 1 expression regulates acute myeloid leukemia cell metabolism by regulating the equilibrium between the rate of glycolysis and oxidative phosphorylation
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 138
    Online Volltext: dx.doi.org/ (Open Access)
  • Goldschmidt, Hartmut; Mai, Elias K; Nievergall, Eva; Fenk, Roland; Bertsch, Uta; Tichy, Diana; Besemer, Britta; Dürig, Jan; Schroers, Roland; Metzler, Ivana v.; Haenel, Mathias; Mann, Christoph; Asemissen, Anne-Marie; Heilmeier, Bernhard; Huhn, Stefanie; Kriegsmann, Katharina; Weinhold, Niels; Luntz, Steffen P.; Holderried, Tobias A. W.; Trautmann-Grill, Karolin; Gezer, Deniz; Klaiber-Hakimi, Maika; Mueller, Martin; Khandanpour, Cyrus; Knauf, Wolfgang; Munder, Markus; Geer, Thomas; Riesenberg, Hendrik; Thomalla, Joerg; Hoffmann, Martin; Raab, Marc-Steffen; Salwender, Hans; Weisel, Katja;
    Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients : The Phase III GMMG-HD7 Trial
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 463 - 465
    Online Volltext: dx.doi.org/ (Open Access)
  • Noman, Helal Mohammed Mohammed Ahmed; Al-Matary, Yahya Saleh; Nimmagadda, Subbaiah Chary; Patnana, Pradeep Kumar; Liu, Longlong; Wei, Lanying; Frank, Daria; Lenz, Georg; Khandanpour, Cyrus;
    Leukaemia Cells Induced Metabolic Alterations in AML Associated Mesenchymal Stem Cells Via Notch Signalling
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 4347 - 4348
    Online Volltext: dx.doi.org/ (Open Access)
  • Patnana, Pradeep Kumar; Behrens, M.; Klotz, L.; Liebmann, M.; Frank, D.; Nimmagadda, C.; Siveke, Jens; Trajkovic-Arsic, Marija; Hanenberg, Helmut; Thivakaran, Aniththa; Khandanpour, Cyrus;
    Growth factor independence 1 expression induced metabolic vulnerabilities and presents novel therapeutic opportunities in acute myeloid leukemia
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 43 - 44
    Online Volltext: dx.doi.org/ (Open Access)
  • Heinrichs, D.; Schütte, Jochen; Thivakaran, A.; Al-Matary, Y.; Suslo, M.; Dührsen, U.; Khandanpour, Cyrus;
    Curcumin as a treatment approach for MDS/AML in human
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 76
    Online Volltext: dx.doi.org/ (Open Access)
  • Fiori, M. N.; Al-Matary, Y.; Fraszczak, J.; Heinrichs, D.; Opalka, Bertram; Dührsen, U.; Möröy, T.; Khandanpour, Cyrus;
    The bone marrow niche as a potential target to improve the outcome of acute myeoloid leukemia using dexamethasone
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 73 - 74
    Online Volltext: dx.doi.org/ (Open Access)
  • Phelan, James D.; Khandanpour, Cyrus; Horman, Shane; Gaudreau, Marie-Claude; Zhu, Jinfang; Paul, William E.; Dührsen, Ulrich; Grimes, H. Leighton; Moroy, Tarik
    Growth Factor Independent-1 (Gfi1) Is Critically Required for T-Cell Acute Lymphoblastic Leukemia (T-ALL) Tumor Initiation and Maintenance
    In: Blood Jg. 116 (2010) Nr. 21, S. 1299
    Online Volltext: dx.doi.org/

    • Bücher/Sammelwerke/Tagungsbände

  • Khandanpour, Cyrus
    Funktion der Transkriptonsfaktoren Gfi1 und Gfi1b in der physiologischen und malignen Entwicklung des hämatopoetischen Systems
    Duisburg ; Essen (2017) 1 CD-ROM

    • Dissertation

  • Khandanpour, Cyrus;
    Affinitätschromatographie mit orientiert und nicht-orientiert immobilisiertem Calmodulin am Beispiel der Aufreinigung der Ubiquityl-Calmodulin-Synthetase Faktor 2
    Duisburg-Essen (2005) 99 Bl. : Ill., graph. Darst.
    Online Volltext

    • Poster / Posterbeiträge

  • Eisfeld, C.; Kajüter, H.; Möller, L.; Oesterling, F.; Khandanpour, Cyrus; Stang, Andreas;
    Entwicklungen im Überleben beim Multiplen Myelom : eine Analyse des Krebsregisters NRW
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 85 - 86
    Online Volltext: dx.doi.org/ (Open Access)