Personensuche
Personensuche
Es wurde 1 Person gefunden.
Funktionen
-
, Zentrum für Innere Medizin
Aktuelle Veranstaltungen
Keine aktuellen Veranstaltungen.
Vergangene Veranstaltungen (max. 10)
-
2020 WS
-
2020 SS
-
2019 WS
-
2019 SS
-
2018 WS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
-
Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple MyelomaIn: Cancers Jg. 15 (2023) Nr. 8,ISSN: 2072-6694Online Volltext: dx.doi.org/ (Open Access)
-
Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCsIn: Frontiers in Cell and Developmental Biology Jg. 11 (2023)ISSN: 2296-634XOnline Volltext: dx.doi.org/ (Open Access)
-
Addition of isatuximab to lenalidomide, bortezomib, and dexamethasone as induction therapy for newly diagnosed, transplantation-eligible patients with multiple myeloma (GMMG-HD7) : Part 1 of an open-label, multicentre, randomised, active-controlled, phase 3 trialIn: The Lancet Haematology Jg. 9 (2022) Nr. 11, S. e810 - e821ISSN: 2352-3026Online Volltext: dx.doi.org/
-
Curcumin as an epigenetic therapeutic agent in myelodysplastic syndromes (Mds)In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 1,ISSN: 1422-0067; 1661-6596Online Volltext: dx.doi.org/ (Open Access)
-
Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cellsIn: British Journal of Haematology Jg. 196 (2022) Nr. 4, S. 995 - 1006ISSN: 1365-2141; 0007-1048Online Volltext: dx.doi.org/ (Open Access)
-
GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemiaIn: Leukemia (2022) in pressISSN: 1476-5551; 0887-6924Online Volltext: dx.doi.org/ (Open Access)
-
High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid LeukemiaIn: Cancers Jg. 14 (2022) Nr. 3,ISSN: 2072-6694Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Presence of the GFI1-36N single nucleotide polymorphism enhances the response of MLL-AF9 leukemic cells to CDK4/6 inhibitionIn: Frontiers in Oncology Jg. 12 (2022)ISSN: 2234-943XOnline Volltext: dx.doi.org/ (Open Access)
-
Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in miceIn: Leukemia Jg. 33 (2019) Nr. 1, S. 110 - 121ISSN: 1476-5551; 0887-6924Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.In: Nature Communications Jg. 9 (2018) S. 1418ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access)
-
GFI1 is required for RUNX1/ETO positive acute myeloid leukemiaIn: Haematologica Jg. 103 (2018) Nr. 9, S. e395 - e399ISSN: 1592-8721; 0390-6078Online Volltext: dx.doi.org/ (Open Access)
-
Gfi1b : A key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndromeIn: Haematologica Jg. 103 (2018) Nr. 4, S. 614 - 625ISSN: 1592-8721; 0390-6078Online Volltext: dx.doi.org/ (Open Access)
-
Enforced GFI1 expression impedes human and murine leukemic cell growth.In: Scientific Reports Jg. 7 (2017) S. 15720ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access)
-
GFI1B-A novel oncosuppressor which restricts number of leukemic stem stellsIn: Haematologica Jg. 102 (2017) Nr. Suppl. 2, S. 204 - 204ISSN: 0390-6078; 1592-8721
-
Growth factor independence 1 (GFI !) regulates the AML supporting function of mesenchymal stromal cellsIn: Haematologica Jg. 102 (2017) Nr. Suppl. 2, S. 459 - 459ISSN: 0390-6078; 1592-8721
-
Myelodysplastic syndromes and bone loss in mice and menIn: Leukemia Jg. 31 (2017) Nr. 4, S. 1003 - 1007ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
-
A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2AIn: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 101 (2016) Nr. 3, S. 1016 - 1022ISSN: 0021-972X; 1945-7197Online Volltext: dx.doi.org/ (Open Access)
-
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent mannerIn: Haematologica Jg. 101 (2016) Nr. 10, S. 1216 - 1227ISSN: 0390-6078; 1592-8721Online Volltext: dx.doi.org/ (Open Access)
-
Bone homeostasis is altered in a mouse model of myelodysplastic syndromeIn: Oncology Research and treatment Jg. 39 3 (2016) S. 123 - 123ISSN: 2296-5270
-
Bone homeostasis is significantly altered in a myelodysplastic syndrome mouse modelIn: Haematologica Jg. 101 1 (2016) S. 493 - 493ISSN: 0390-6078; 1592-8721(Open Access)
-
Epigenetic therapy as a novel approach for GFI136N-associated murine/human AMLIn: Experimental Hematology Jg. 44 (2016) Nr. 8, S. 713 - 726.e14ISSN: 1873-2399; 0301-472XOnline Volltext: dx.doi.org/ (Open Access)
-
Functional inhibition of mesenchymal stromal cells in acute myeloid leukemiaIn: Leukemia Jg. 30 (2016) Nr. 3, S. 683 - 691ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
-
GFI1 as a novel prognostic and therapeutic factor for AML/MDSIn: Leukemia Jg. 30 (2016) Nr. 6, S. 1237 - 1245ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
-
GFI136N as a therapeutic and prognostic marker for myelodysplastic syndromeIn: Experimental Hematology Jg. 44 (2016) Nr. 7, S. 590 - 595.e1ISSN: 1873-2399; 0301-472XOnline Volltext: dx.doi.org/ (Open Access)
-
High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine ModelIn: Cellular Physiology and Biochemistry Jg. 38 (2016) Nr. 4, S. 1343 - 1353ISSN: 1015-8987; 1421-9778Online Volltext: dx.doi.org/ (Open Access)
-
Low GFI1 expression level drive the development of acute myeloid leukemia and fatal myeloproliferative neoplasia by blocking differentiation and P53-mediated apoptosisIn: Experimental Hematoloy Jg. 44 1 (2016) Nr. 9, S. 71 - S71ISSN: 0301-472XOnline Volltext: dx.doi.org/
-
Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1In: PLoS ONE Jg. 11 (2016) Nr. 7, S. e0160344ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
-
Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8 + T-cell priming and viral controlIn: Scientific Reports Jg. 6 (2016) S. 19191ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access)
-
72 personalized treatment approach for GFI 136N heterozygous or homozygous MDS patientsIn: Leukemia Research Jg. 39 (2015) Nr. Suppl. 1, S. S35ISSN: 1873-5835Online Volltext: dx.doi.org/
-
From cytopenia to leukemia : the role of Gfi1 and Gfi1b in blood formationIn: Blood Jg. 126 (2015) Nr. 24, S. 2561 - 2569ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
A dominant-negative GFI1B mutation in the gray platelet syndromeIn: The New England Journal of Medicine Jg. 370 (2014) Nr. 3, S. 245 - 253ISSN: 1533-4406; 0028-4793Online Volltext: dx.doi.org/ (Open Access)
-
Gfi1 as a novel prognostic marker and tumor suppressor in acute myeloid leukemiaIn: Onkologie Jg. 36 7 (2013) S. 193 - 193ISSN: 0378-584X; 1423-0240
-
Gfi1 as a regulator of p53 and a therapeutic target for ALLIn: OncoTarget Jg. 4 (2013) Nr. 3, S. 374 - 375ISSN: 1949-2553Online Volltext: dx.doi.org/
-
Gfi136N is a novel prognostic marker for the progression of myelodysplastic syndrome to Acute myeloid leukemiaIn: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 188 - 188ISSN: 0378-584X; 1423-0240
-
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemiaIn: Cancer Cell Jg. 23 (2013) Nr. 2, S. 200 - 214ISSN: 1535-6108; 1878-3686Online Volltext: dx.doi.org/ (Open Access)
-
Hand-foot syndrome : common presentation in an uncommon situationIn: European Journal of Haematology Jg. 91 (2013) Nr. 5, S. 472ISSN: 1600-0609; 0902-4441; 0036-553XOnline Volltext: dx.doi.org/
-
Leukämien : Modellkrankheiten für die Entstehung und Behandlung von KrebsIn: Unikate: Berichte aus Forschung und Lehre (2013) Nr. 44: Medizin : 50 Jahre Universitätsklinikum Essen, S. 114 - 125ISBN: 978-3-934359-44-4 ISSN: 0944-6060; 1869-3881Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Origin of the brush cell lineage in the mouse intestinal epitheliumIn: Developmental Biology Jg. 362 (2012) Nr. 2, S. 194 - 218ISSN: 0012-1606; 1095-564XOnline Volltext: dx.doi.org/
-
The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in miceIn: Blood Jg. 120 (2012) Nr. 19, S. 4006 - 4017ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
-
Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activationIn: Seminars in immunology Jg. 23 (2011) Nr. 5, S. 368 - 378ISSN: 1096-3618Online Volltext: dx.doi.org/
-
Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like diseaseIn: Stem Cells Jg. 29 (2011) Nr. 2, S. 376 - 385ISSN: 1549-4918; 1066-5099Online Volltext: dx.doi.org/
-
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemiaIn: Blood Jg. 115 (2010) Nr. 12, S. 2462 - 2472ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
-
Evidence that Growth factor independence 1b (Gfi1b) regulates dormancy and peripheral blood mobilization of hematopoietic stem cellsIn: Blood Jg. 116 (2010) Nr. 24, S. 5149 - 5161ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
-
Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65In: Molecular and cellular biology : MCB Jg. 30 (2010) Nr. 16, S. 3929 - 3942ISSN: 1098-5549Online Volltext: dx.doi.org/
-
Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemiaIn: International Journal of Hematology Jg. 89 (2009) Nr. 4, S. 422 - 430ISSN: 1865-3774Online Volltext: dx.doi.org/
-
The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Iγ2b germline transcriptsIn: European Journal of Immunology Jg. 38 (2008) Nr. 11, S. 2916 - 3244ISSN: 1521-4141; 0014-2980Online Volltext: dx.doi.org/
-
Entwicklungen im Überleben beim Multiplen Myelom : eine Analyse des Krebsregisters NRW
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 85 - 86ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584XOnline Volltext: dx.doi.org/ (Open Access) -
Leukaemia Cells Induced Metabolic Alterations in AML Associated Mesenchymal Stem Cells Via Notch SignallingIn: Blood Jg. 138 (2021) Nr. Suppl. 1,ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
-
Growth factor independence 1 expression induced metabolic vulnerabilities and presents novel therapeutic opportunities in acute myeloid leukemia
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 43 - 44ISSN: 2296-5270; 2296-5262; 1423-0240; 0378-584XOnline Volltext: dx.doi.org/ (Open Access) -
Curcumin as a treatment approach for MDS/AML in human
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 76ISSN: 2296-5262; 2296-5270Online Volltext: dx.doi.org/ (Open Access) -
The bone marrow niche as a potential target to improve the outcome of acute myeoloid leukemia using dexamethasone
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 73 - 74ISSN: 2296-5262; 2296-5270Online Volltext: dx.doi.org/ (Open Access) -
Growth Factor Independent-1 (Gfi1) Is Critically Required for T-Cell Acute Lymphoblastic Leukemia (T-ALL) Tumor Initiation and MaintenanceIn: Blood Jg. 116 (2010) Nr. 21, S. 1299ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
-
Funktion der Transkriptonsfaktoren Gfi1 und Gfi1b in der physiologischen und malignen Entwicklung des hämatopoetischen SystemsDuisburg ; Essen (2017) 1 CD-ROM
-
Affinitätschromatographie mit orientiert und nicht-orientiert immobilisiertem Calmodulin am Beispiel der Aufreinigung der Ubiquityl-Calmodulin-Synthetase Faktor 2Duisburg-Essen (2005) 99 Bl. : Ill., graph. Darst.