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Dr. rer. medic. Andreas Skyschally

Funktionen

  • Mitglied/er, Institut für Pathophysiologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Braczko, Felix; Skyschally, Andreas; Lieder, Helmut; Kather, Jakob Nikolas; Kleinbongard, Petra; Heusch, Gerd
    Deep learning segmentation model for quantification of infarct size in pigs with myocardial ischemia/reperfusion
    In: Basic Research in Cardiology , Jg. 119 2024, Nr. 6, S. 923 – 936
    DOI (Open Access)
  • Lieder, Helmut; Paket, Umut; Skyschally, Andreas; Rink, Andreas D.; Baars, Theodor; Neuhäuser, Markus; Kleinbongard, Petra; Heusch, Gerd
    Vago-splenic signal transduction of cardioprotection in humans
    In: European Heart Journal , Jg. 45 2024, Nr. 34, S. 3164 – 3177
    DOI
  • Skyschally, Andreas; Kleinbongard, Petra; Neuhäuser, Markus; Heusch, Gerd
    “Expression of concern” : Publication bias for positive preclinical cardioprotection studies
    In: Basic Research in Cardiology , Jg. 119 2024, Nr. 3, S. 397 – 402
    DOI (Open Access)
  • Lieder, Helmut Raphael; Adam, Virginie; Skyschally, Andreas; Sturek, Michael; Kleinbongard, Petra; Heusch, Gerd
    Attenuation of ST-segment elevation by ischemic preconditioning : Reflection of cardioprotection in Göttingen but not in Ossabaw minipigs
    In: International Journal of Cardiology , Jg. 386 2023, S. 109 – 117
    DOI
  • Kleinbongard, Petra; Lieder, Helmut; Skyschally, Andreas; Heusch, Gerd
    Diazoxide is a powerful cardioprotectant but is not feasible in a realistic infarct scenario
    In: Frontiers in Cardiovascular Medicine , Jg. 10 2023, 1173462
    DOI (Open Access)
  • Kleinbongard, Petra; Lieder, Helmut Raphael; Skyschally, Andreas; Heusch, Gerd
    No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs
    In: Basic Research in Cardiology , Jg. 118 2023, Nr. 1, 23
    DOI (Open Access)
  • Kleinbongard, Petra; Lieder, Helmut; Skyschally, Andreas; Heusch, Gerd
    No sex-related differences in infarct size, no-reflow, and protection by ischaemic pre-conditioning in Göttingen minipigs
    In: Cardiovascular Research 2023
    DOI
  • Kleinbongard, Petra; Lieder, Helmut Raphael; Skyschally, Andreas; Alloosh, Mouhamad; Gödecke, Axel; Rahmann, Sven; Sturek, Michael; Heusch, Gerd
    Non-responsiveness to cardioprotection by ischaemic preconditioning in Ossabaw minipigs with genetic predisposition to, but without the phenotype of the metabolic syndrome
    In: Basic Research in Cardiology , Jg. 117 2022, Nr. 1, 58
    DOI (Open Access)
  • Lieder, Helmut Raphael; Skyschally, Andreas; Sturek, Michael; Heusch, Gerd; Kleinbongard, Petra
    Remote ischemic conditioning in Ossabaw minipigs induces the release of humoral cardioprotective triggers, but the myocardium does not respond with reduced infarct size
    In: American Journal of Physiology: Heart and Circulatory Physiology , Jg. 323 2022, Nr. 6, S. H1365 – H1375
    DOI
  • Kleinbongard, Petra; Lieder, Helmut; Braczko, Felix; Skyschally, Andreas; Heusch, Gerd
    Activation of a non‐neuronal cholinergic system in rat cardiomyocytes by cardioprotective humoral factors from pigs with remote ischemic conditioning
    In: The FASEB Journal , Jg. 34 2020, Nr. S1, S. 1 – 1
    DOI (Open Access)
  • Amanakis, Georgios; Kleinbongard, Petra; Heusch, Gerd; Skyschally, Andreas
    Attenuation of ST-segment elevation after ischemic conditioning maneuvers reflects cardioprotection online
    In: Basic Research in Cardiology , Jg. 114 2019, Nr. 3, S. 22
    DOI
  • Skyschally, Andreas; Hagelschuer, Helene; Kleinbongard, Petra; Heusch, Gerd
    Larger infarct size but equal protection by ischemic conditioning in septum and anterior free wall of pigs with LAD occlusion
    In: Physiological Reports , Jg. 7 2019, Nr. 19, e14236
    DOI, Online Volltext (Open Access)
  • Lieder, Helmut Raphael; Skyschally, Andreas; Heusch, Gerd; Kleinbongard, Petra
    Plasma from remotely conditioned pigs reduces infarct size when given before or after ischemia to isolated perfused rat hearts
    In: Pflügers Archiv: European Journal of Physiology , Jg. 471 2019, Nr. 11/12, S. 1371 – 1379
    DOI
  • Heusch, Gerd; Skyschally, Andreas; Kleinbongard, Petra
    Coronary microembolization and microvascular dysfunction
    In: International Journal of Cardiology , Jg. 258 2018, S. 17 – 23
    DOI
  • Skyschally, Andreas; Kleinbongard, Petra; Lieder, Helmut; Gedik, Nilgün; Stoian, Leanda; Amanakis, Georgios; Elbers, Etienne; Heusch, Gerd
    Humoral transfer and intramyocardial signal transduction of protection by remote ischemic perconditioning in pigs, rats, and mice
    In: American Journal of Physiology: Heart and Circulatory Physiology , Jg. 315 2018, Nr. 1, S. H159 – H172
    DOI (Open Access)
  • Helfritz, Fabian A.; Bojkova, Denisa; Wanders, Verena; Kuklinski, Nina; Westhaus, Sandra; von Horn, Charlotte; Rauen, Ursula; Gallinat, Anja; Baba, Hideo Andreas; Skyschally, Andreas; Swoboda, Sandra; Kinast, Volker; Steinmann, Eike; Heusch, Gerd; Minor, Thomas; Meuleman, Philip; Paul, Andreas; Ciesek, Sandra
    Methylene Blue Treatment of Grafts During Cold Ischemia Time Reduces the Risk of Hepatitis C Virus Transmission
    In: The Journal of Infectious Diseases (JID) , Jg. 218 2018, Nr. 11, S. 1711 – 1721
    DOI (Open Access)
  • Bøtker, Hans Erik; Hausenloy, Derek; Andreadou, Ioanna; Antonucci, Salvatore; Boengler, Kerstin; Davidson, Sean M.; Deshwal, Soni; Devaux, Yvan; Di Lisa, Fabio; Di Sante, Moises; Efentakis, Panagiotis; Femminò, Saveria; García-Dorado, David; Giricz, Zoltán; Ibanez, Borja; Iliodromitis, Efstathios; Kaludercic, Nina; Kleinbongard, Petra; Neuhäuser, Markus; Ovize, Michel; Pagliaro, Pasquale; Rahbek-Schmidt, Michael; Ruiz-Meana, Marisol; Schlüter, Klaus-Dieter; Schulz, Rainer; Skyschally, Andreas; Wilder, Catherine; Yellon, Derek M.; Ferdinandy, Peter; Heusch, Gerd
    Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection
    In: Basic Research in Cardiology , Jg. 113 2018, Nr. 5, S. 39
    DOI (Open Access)
  • Kleinbongard, Petra; Amanakis, Georgios; Skyschally, Andreas; Heusch, Gerd
    Reflection of Cardioprotection by Remote Ischemic Perconditioning in Attenuated ST-Segment Elevation During Ongoing Coronary Occlusion in Pigs : Evidence for Cardioprotection From Ischemic Injury
    In: Circulation Research , Jg. 122 2018, Nr. 8, S. 1102 – 1108
    DOI (Open Access)
  • Kleinbongard, Petra; Skyschally, Andreas; Gent, Sabine; Pesch, Marion; Heusch, Gerd
    STAT3 as a common signal of ischemic conditioning : a lesson on "rigor and reproducibility" in preclinical studies on cardioprotection
    In: Basic Research in Cardiology , Jg. 113 2018, Nr. 1, S. 3
    DOI
  • Heusch, Gerd; Skyschally, Andreas; Kleinbongard, Petra
    Translation, Translation, Translation
    In: Circulation Research , Jg. 123 2018, Nr. 8, S. 931 – 933
    DOI (Open Access)
  • Lieder, Helmut Raphael; Kleinbongard, Petra; Skyschally, Andreas; Hagelschuer, Helene; Chilian, William M.; Heusch, Gerd
    Vago-splenic axis in signal transduction of remote ischemic preconditioning in pigs and rats
    In: Circulation Research , Jg. 123 2018, Nr. 10, S. 1152 – 1163
    DOI (Open Access)
  • Gedik, Nilguen; Maciel, Leonardo; Schulte, Christiane; Skyschally, Andreas; Heusch, Gerd; Kleinbongard, Petra
    Cardiomyocyte mitochondria as targets of humoral factors released by remote ischemic preconditioning
    In: Archives of Medical Science , Jg. 13 2017, Nr. 2, S. 448 – 458
    DOI (Open Access)
  • Kleinbongard, Petra; Skyschally, Andreas; Heusch, Gerd
    Cardioprotection by remote ischemic conditioning and its signal transduction
    In: Pflügers Archiv: European Journal of Physiology , Jg. 469 2017, Nr. 2, S. 159 – 181
    DOI
  • Kleinbongard, Petra; Skyschally, Andreas; Heusch, Gerd
    Erratum to: Cardioprotection by remote ischemic conditioning and its signal transduction
    In: Pflügers Archiv: European Journal of Physiology , Jg. 469 2017, Nr. 5-6, S. 843
    DOI
  • Skyschally, Andreas; Amanakis, Georgios; Neuhäuser, Markus; Kleinbongard, Petra; Heusch, Gerd
    Impact of electrical defibrillation on infarct size and no-reflow in pigs subjected to myocardial ischemia-reperfusion without and with ischemic conditioning
    In: American Journal of Physiology: Heart and Circulatory Physiology , Jg. 313 2017, Nr. 5, S. H871 – H878
    DOI
  • Kleinbongard, Petra; Lieder, H.; Gent, S.; Skyschally, Andreas; Heusch, Gerd
    Infarct size reduction by remote ischemic perconditioning and humoral transfer of protection across species
    In: The FASEB Journal , Jg. 31 2017, Nr. Suppl. 1
  • Gent, Sabine; Skyschally, Andreas; Kleinbongard, Petra; Heusch, Gerd
    Lschemic preconditioning in pigs : A causal role for signal transducer and activator of transcription 3
    In: American Journal of Physiology: Heart and Circulatory Physiology , Jg. 312 2017, Nr. 3, S. H478 – H484
    DOI
  • Gedik, Nilgün; Krüger, Marcus; Thielmann, Matthias Klaus; Kottenberg, Eva; Skyschally, Andreas; Frey, Ulrich; Cario, Elke; Peters, Jürgen; Jakob, Heinz G.; Heusch, Gerd; Kleinbongard, Petra
    Proteomics/phosphoproteomics of left ventricular biopsies from patients with surgical coronary revascularization and pigs with coronary occlusion/reperfusion : Remote ischemic preconditioning
    In: Scientific Reports , Jg. 7 2017, Nr. 1
    DOI (Open Access)
  • Skyschally, Andreas; Gent, Sabine; Amanakis, Georgios; Schulte, Christiane; Kleinbongard, Petra; Heusch, Gerd
    Across-Species Transfer of Protection by Remote Ischemic Preconditioning With Species-Specific Myocardial Signal Transduction by Reperfusion Injury Salvage Kinase and Survival Activating Factor Enhancement Pathways
    In: Circulation Research , Jg. 117 2015, Nr. 3, S. 279 – 288
    DOI (Open Access)
  • Skyschally, Andreas; Amanakis, G.; Heusch, Gerd
    Myocardial protection by ischemic preconditioning is already evident during early index ischemia : analysis of ST-segment deviation during ischemia/reperfusion in pigs
    In: Cardiovascular Research , Jg. 103 2014, Nr. Suppl. 1, S. 118
    DOI
  • Baars, Theodor; Skyschally, Andreas; Klein-Hitpaß, Ludger; Cario, Elke; Erbel, Raimund; Heusch, Gerd; Kleinbongard, Petra
    microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigs
    In: Pflügers Archiv: European Journal of Physiology , Jg. 466 2014, Nr. 10, S. 1953 – 1961
    DOI
  • Skyschally, Andreas; Walter, Barbara; Heusch, Gerd
    Coronary microembolization during early reperfusion: Infarct extension, but protection by ischaemic postconditioning
    In: European Heart Journal , Jg. 34 2013, Nr. 42, S. 3314 – 3321
    DOI
  • Gedik, Nilguen; Heusch, Gerd; Skyschally, Andreas
    Infarct size reduction by cyclosporine A at reperfusion involves inhibition of the mitochondrial permeability transition pore but does not improve mitochondrial respiration
    In: Archives of Medical Science , Jg. 9 2013, Nr. 6, S. 968 – 975
    DOI (Open Access)
  • Heusch, Gerd; Kleinbongard, Petra; Skyschally, Andreas
    Myocardial infarction and coronary microvascular obstruction: an intimate, but complicated relationship
    In: Basic Research in Cardiology , Jg. 108 2013, Nr. 6, S. 380
    DOI
  • Skyschally, Andreas; Walter, Barbara; Heusch, Gerd; Hansen, Rie Schultz
    The anti-arrhythmic di-peptide ZP1609 (Danegaptide) when given at reperfusion reduces myocardial infarct size in pigs
    In: Journal of the American College of Cardiology (JACC) , Jg. 61 2013, Nr. 10 Suppl., S. E67
    DOI
  • Skyschally, Andreas; Walter, Barbara; Schultz Hansen, Rie; Heusch, Gerd
    The antiarrhythmic dipeptide ZP1609 (danegaptide) when given at reperfusion reduces myocardial infarct size in pigs
    In: Naunyn-Schmiedeberg's Archives of Pharmacology , Jg. 386 2013, Nr. 5, S. 383 – 391
    DOI
  • Heusch, Gerd; Kleinbongard, Petra; Skyschally, Andreas; Levkau, Bodo; Schulz, Rainer; Erbel, Raimund
    The coronary circulation in cardioprotection : More than just one confounder
    In: Cardiovascular Research , Jg. 94 2012, Nr. 2, S. 237 – 245
    DOI
  • Heusch, Gerd; Skyschally, Andreas; Schulz, Rainer
    Cardioprotection by Ivabradine Through Heart Rate Reduction and Beyond
    In: Journal of Cardiovascular Pharmacology and Therapeutics , Jg. 16 2011, Nr. 3-4, S. 281 – 284
    DOI
  • Heusch, Gerd; Musiolik, Judith; Gedik, Nilguen; Skyschally, Andreas
    Mitochondrial STAT3 Activation and Cardioprotection by Ischemic Postconditioning in Pigs With Regional Myocardial Ischemia/Reperfusion
    In: Circulation Research , Jg. 109 2011, Nr. 11, S. 1302 – 1308
    DOI
  • Skyschally, Andreas; Heusch, Gerd
    Reduction of Myocardial Infarct Size by Dronedarone in Pigs—A Pleiotropic Action?
    In: Cardiovascular Drugs and Therapy , Jg. 25 2011, Nr. 3, S. 197 – 201
    DOI (Open Access)
  • Heusch, Gerd; Skyschally, Andreas; Schulz, Rainer
    The in-situ pig heart with regional ischemia/reperfusion - Ready for translation
    In: Journal of Molecular and Cellular Cardiology , Jg. 50 2011, Nr. 6, S. 951 – 963
    DOI
  • Skyschally, Andreas; Schulz, Rainer; Heusch, Gerd
    Cyclosporine a at reperfusion reduces infarct size in pigs : Letter to the Editor
    In: Cardiovascular Drugs and Therapy , Jg. 24 2010, Nr. 1, S. 85 – 87
    DOI (Open Access)
  • Musiolik, Judith; Van Caster, Patrick; Skyschally, Andreas; Böngler, Kerstin; Gres, Petra; Schulz, Rainer; Heusch, Gerd
    Reduction of infarct size by gentle reperfusion without activation of reperfusion injury salvage kinases in pigs
    In: Cardiovascular Research , Jg. 85 2010, Nr. 1, S. 110 – 117
    DOI

    • Abstracts

  • Schulte, C.; Skyschally, Andreas; Heusch, Gerd; Kleinbongard, Petra
    Humoral transfer of remote ischemic preconditionings protection from donor pigs in vivo to an in in vitro bioassay of isolated perfused recipient rat hearts
    93rd Annual Meeting of the German Physiological Society, 13‐15 March 2014, Mainz, Germany,
    In: Acta Physiologica , Jg. 210 2014, Nr. S695, S. 93 – 94
    DOI
  • Skyschally, Andreas; Schulte, C.; Heusch, Gerd; Kleinbongard, Petra
    P157: Humoral transfer of remote ischemic preconditioning′s protection from donor pigs in vivo to an in in vitro bioassay of isolated perfused recipient rat hearts
    In: Cardiovascular Research , Jg. 103 2014, Nr. Suppl. 1, S. S27
    DOI (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Heusch, Gerd; Skyschally, Andreas; Kleinbongard, Petra
    Coronary microembolization and microvascular dysfunction
    In: Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment / Niccoli, Giampaolo; Eitel, Ingo (Hrsg.) 2018, S. 83 – 96
    DOI

    • Bücher/Sammelwerke/Tagungsbände

  • Skyschally, Andreas
    Koronare Mikroembolisation : Experimentelle Untersuchungen zur Charakterisierung des mikroembolisierten Myokards, insbesondere zur interakton der koronaren Mikroembolisation mit der ischämischen Präkonditionierung des Herzen
    Duisburg, Essen 2008