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Institut für Pathologie am Universitätsklinikum Essen
Funktionen
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Professor/in, Institut für Pathologie
Aktuelle Veranstaltungen
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WiSe 2025
Vergangene Veranstaltungen (max. 10)
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SoSe 2025
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WiSe 2024
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SoSe 2024
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WiSe 2023
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SoSe 2023
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Corrigendum to “Ex vivo use of a Rho-kinase inhibitor during renal preservation improves graft function upon reperfusion”In: Cryobiology, Jg. 120, 2025, 105255
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The Diagnostic Role of TFF1, TFF3, FOXA1, CA XII and TRPS1 in Serous EffusionsIn: Cytopathology, 2025, in press
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The Impact of Cancer-Associated Fibroblasts on the Biology and Progression of Colorectal CarcinomasIn: Genes, Jg. 15, 2024, Nr. 2, 209DOI (Open Access)
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Cancer-Associated Fibroblasts Influence Survival in Pleural Mesothelioma : Digital Gene Expression Analysis and Supervised Machine Learning ModelIn: International Journal of Molecular Sciences (IJMS), Jg. 24, 2023, Nr. 15, 12426DOI (Open Access)
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Fibroblast activation protein-α expression in fibroblasts is common in the tumor microenvironment of colorectal cancer and may serve as a therapeutic targetIn: Pathology & Oncology Research, Jg. 29, 2023, 1611163DOI (Open Access)
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Induction of metallothionein expression by supplementation of zinc induces resistance against platinum-based treatment in malignant pleural mesotheliomaIn: Translational Cancer Research, Jg. 12, 2023, Nr. 8, S. 1929 – 1936DOI (Open Access)
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One Third of Malignant Pleural Mesothelioma Shows High Immunohistochemical Expression of MSLN or CXCR4 Which Indicates Potent Candidates for Endo-RadiotherapyIn: International Journal of Molecular Sciences (IJMS), Jg. 24, 2023, Nr. 7, S. 6356DOI (Open Access)
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Cancer-Associated Fibroblasts Regulate Kinase Activity in Mesothelioma Cell Lines via Paracrine Signaling and Thereby Dictate Cell Faith and BehaviorIn: International Journal of Molecular Sciences (IJMS), Jg. 23, 2022, Nr. 6, 3278DOI (Open Access)
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Bericht der Arbeitsgemeinschaft Herz‑, Gefäß‑, Nieren- und TransplantationspathologieIn: Der Pathologe, Jg. 42, 2021, S. 186 – 187DOI (Open Access)
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Digital gene expression analysis of epithelioid and sarcomatoid mesothelioma reveals differences in immunogenicityIn: Cancers, Jg. 13, 2021, Nr. 8, S. 1761DOI (Open Access)
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Mitogen signal-associated pathways, energy metabolism regulation, and mediation of tumor immunogenicity play essential roles in the cellular response of malignant pleural mesotheliomas to platinum-based treatment : A retrospective studyIn: Translational Lung Cancer Research, Jg. 10, 2021, Nr. 7, S. 3030 – 3042DOI (Open Access)
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Nodulärer Tumor eines Ductus deferens mit epithelialen VerbändenIn: Der Pathologe, Jg. 42, 2021, Nr. 6, S. 598 – 601
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Pulmonary echinococcosis : A rare pseudotumour of the lungIn: Rare Tumors, Jg. 13, 2021, S. 1 – 5DOI (Open Access)
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Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesotheliomaIn: Scientific Reports, Jg. 10, 2020, Nr. 1, S. 18677DOI, Online Volltext (Open Access)
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Lebertransplantation : Aktuelle Aspekte der Prätransplantationsdiagnostik und AbstoßungIn: Der Pathologe, Jg. 41, 2020, Nr. 5, S. 505 – 514
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Mesotheliale Proliferate der Tunica vaginalis testisIn: Der Pathologe, Jg. 41, 2020, Nr. 4, S. 406 – 410
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Villitis of unknown etiology and chronic deciduitis are not associated with human papilloma virus and enterovirus infectionIn: Virchows Archiv, 2020
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Antiretroviral therapy suppresses rectal HIV-RNA shedding despite inflammation in MSM with rectal C. trachomatis and N. gonorrhoeae infections - A cross-sectional, single-center studyIn: Sexually Transmitted Infections, Jg. 95, 2019, Nr. 2, S. 95 – 98DOI (Open Access)
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Bortezomib sensitivity is tissue dependent and high expression of the 20S proteasome precludes good response in malignant pleural mesotheliomaIn: Cancer Management and Research, Jg. 11, 2019, S. 8711 – 8720DOI (Open Access)
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Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitroIn: BMC Cancer, Jg. 19, 2019, Nr. 1, 108DOI (Open Access)
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Lungentransplantation : Histomorphologische Diagnostik und klinische AspekteIn: Der Pathologe, Jg. 40, 2019, Nr. 3, S. 281 – 291
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Papilloma of the Fallopian Tube : A Rare Gynecologic Neoplasm Harboring a BRAF (c.1799T>A) Mutation (V600E)In: International Journal of Gynecological Pathology, Jg. 38, 2019, Nr. 5, S. 459 – 463
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Prediction Of Microvascular Tumor Invasion In Liver Transplant Candidates With Hepatocellular Carcinoma : A Feasible Concept Or A Misleading Illusion?In: Transplantation Proceedings, Jg. 51, 2019, Nr. 2, S. 421 – 423
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Screening of Pleural Mesothelioma Cell Lines for Kinase Activity May Identify New Mechanisms of Therapy Resistance in Patients Receiving Platin-Based ChemotherapyIn: Journal of Oncology, 2019, 2902985DOI (Open Access)
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Setting out the frame conditions for feasible use of FFPE derived RNAIn: Pathology, Research and Practice, Jg. 215, 2019, Nr. 2, S. 381 – 386
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Transbronchial cryobiopsy in fibrosing interstitial lung disease : Modifications of the procedure lead to risk reductionIn: Thorax, Jg. 74, 2019, Nr. 7, S. 711 – 714
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Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapyIn: OncoTarget, Jg. 9, 2018, Nr. 32, S. 22254 – 22268DOI (Open Access)
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Inhibition of MDM2 via Nutlin-3A : A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53In: Journal of Oncology, 2018, 1986982DOI (Open Access)
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Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancerIn: PLoS ONE, Jg. 13, 2018, Nr. 5, S. e0195716DOI (Open Access)
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Processing Escape Mechanisms Through Altered Proteasomal Cleavage of Epitopes Affect Immune Response in Pulmonary Neuroendocrine TumorsIn: Technology in Cancer Research & Treatment (TCRT), Jg. 17, 2018DOI (Open Access)
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The diagnostic role of PTEN and ARID1A in serous effusionsIn: Virchows Archiv, Jg. 472, 2018, Nr. 3, S. 425 – 432
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Association of high HLA-E expression during acute cellular rejection and numbers of HLA class I leader peptide mismatches with reduced renal allograft survivalIn: Immunobiology, Jg. 222, 2017, Nr. 3, S. 536 – 543
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Comprehensive biomarker analyses in patients with advanced or metastatic non-small cell lung cancer prospectively treated with the polo-like Kinase 1 Inhibitor BI2536In: Oncology Research and Treatment, Jg. 40, 2017, Nr. 7-8, S. 435 – 439
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miRNA regulation is important for DNA damage repair and recognition in malignant pleural mesotheliomaIn: Virchows Archiv, Jg. 470, 2017, Nr. 6, S. 627 – 637
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ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter TechnologyIn: PLoS ONE, Jg. 11, 2016, Nr. 11, S. e0165181DOI (Open Access)
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Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcomeIn: OncoTarget, Jg. 7, 2016, Nr. 15, S. 20166 – 20179DOI (Open Access)
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Investigation of pharmaceutical targets in pulmonary neuroendocrine tumors by massive parallel sequencing and digital gene expression analysisIn: Oncology Research and Treatment, Jg. 39, 2016, Nr. Suppl. 1, S. 26 – 26
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MMP-7 is a highly specific negative marker for benign and malignant mesothelial cells in serous effusionsIn: Human Pathology, Jg. 47, 2016, Nr. 1, S. 104 – 108
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Massive parallel sequencing and digital gene expression analysis reveals potential mechanisms to overcome therapy resistance in pulmonary neuroendocrine tumorsIn: Journal of Cancer, Jg. 7, 2016, Nr. 15, S. 2165 – 2172DOI, Online Volltext (Open Access)
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Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based ChemotherapyIn: Journal of Cancer, Jg. 7, 2016, Nr. 13, S. 1915 – 1925DOI, Online Volltext (Open Access)
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The role of transbronchial cryobiopsy and surgical lung biopsy in the diagnostic algorithm of interstitial lung diseaseIn: The Clinical Respiratory Journal, Jg. 10, 2016, Nr. 5, S. 589 – 595
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microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesotheliomaIn: OncoTarget, Jg. 7, 2016, Nr. 14, S. 18713 – 18721
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(Cleaved) CK18 serum and tissue expression levels differentiate acute HCV reinfection from acute rejection in liver allograftsIn: Liver International, Jg. 35, 2015, Nr. 3, S. 905 – 913
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A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumorsIn: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Jg. 1854, 2015, Nr. 6, S. 641 – 650
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Arteriosklerose der Koronararterien und Plaque-Progression : histomorphologische und molekularbiologische AspekteIn: Herz: Cardiovascular Diseases, Jg. 40, 2015, Nr. 6, S. 837 – 844
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Ex vivo use of a Rho-kinase inhibitor during renal preservation improves graft function upon reperfusionIn: Cryobiology, Jg. 70, 2015, Nr. 1, S. 71 – 75
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Identification of deregulation of apoptosis and cell cycle in neuroendocrine tumors of the lung via NanoString nCounter expression analysisIn: OncoTarget, Jg. 6, 2015, Nr. 28, S. 24690 – 24698DOI (Open Access)
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Kidney transplantation after oxygenated machine perfusion preservation with Custodiol-N solutionIn: Transplant International, Jg. 28, 2015, Nr. 9, S. 1102 – 1108DOI (Open Access)
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MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53In: British Journal of Cancer (BJC), Jg. 112, 2015, Nr. 5, S. 883 – 890DOI (Open Access)
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Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour groupIn: British Journal of Cancer (BJC), Jg. 113, 2015, Nr. 12, S. 1704 – 1711DOI (Open Access)
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Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factorsIn: BMC Cancer, Jg. 15, 2015, Nr. 1, S. 363DOI (Open Access)
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SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString)In: Future Oncology, Jg. 11, 2015, Nr. 7, S. 1027 – 1036
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Transbronchial Catheter Aspiration and Transbronchial Needle Aspiration in the Diagnostic Workup of Peripheral Lung LesionsIn: Lung, Jg. 193, 2015, Nr. 5, S. 767 – 772
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Activation of angiogenesis differs strongly between pulmonary carcinoids and neuroendocrine carinomas and is crucial for carcinoid tumourgenesisIn: Journal of Cancer, Jg. 5, 2014, Nr. 6, S. 465 – 471DOI (Open Access)
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Alveolar and intraparenchymal proteasome in sarcoidosisIn: Respiratory Medicine, Jg. 108, 2014, Nr. 10, S. 1534 – 1541
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Assessment of Folate Receptor-α and Epidermal Growth Factor Receptor Expression in Pemetrexed-Treated Non–Small-Cell Lung Cancer PatientsIn: Clinical Lung Cancer, Jg. 15, 2014, Nr. 5, S. 320 – 330.e3
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Different micro-RNA expression profiles distinguish subtypes of neuroendocrine tumors of the lung : results of a profiling studyIn: Modern Pathology, Jg. 27, 2014, Nr. 12, S. 1632 – 1640
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Gene expression analysis of the 26S proteasome subunit PSMB4 reveals significant upregulation, different expression and association with proliferation in human pulmonary neuroendocrine tumoursIn: Journal of Cancer, Jg. 5, 2014, Nr. 8, S. 646 – 654DOI (Open Access)
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Increased HLA-E expression during acute cellular rejection in renal transplants is associated with greater loss of renal functionIn: Nephrology Dialysis Transplantation (NDT), Jg. 29, 2014, Nr. Suppl. 3, S. iii531
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Influence of oxygen concentration during hypothermic machine perfusion on porcine kidneys from donation after circulatory deathIn: Transplantation, Jg. 98, 2014, Nr. 9, S. 944 – 950
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Isothermal multiple displacement amplification : a methodical approach enhancing molecular routine diagnostics of microcarcinomas and small biopsiesIn: OncoTargets and Therapy, Jg. 7, 2014, S. 1441 – 1447DOI (Open Access)
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Mdm2 protein expression is strongly associated with survival in malignant pleural mesotheliomaIn: Future Oncology, Jg. 10, 2014, Nr. 6, S. 995 – 1005
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Resection of a Giant Neuroblastoma Misdiagnosed as Atypical Mediastinal CarcinoidIn: Journal of Thoracic Oncology, Jg. 9, 2014, Nr. 1, S. 132 – 134
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Subnormothermic machine perfusion for preservation of porcine kidneys in a donation after circulatory death modelIn: Transplant International, Jg. 27, 2014, Nr. 10, S. 1097 – 1106
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T lymphocytes export proteasomes by way of microparticles : A possible mechanism for generation of extracellular proteasomesIn: Journal of Cellular and Molecular Medicine, Jg. 18, 2014, Nr. 1, S. 59 – 68DOI (Open Access)
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Accelerated hyperfractionated radiotherapy within trimodality therapy concepts for stage IIIA/B non-small cell lung cancer : Markedly higher rate of pathologic complete remissions than with conventional fractionationIn: European Journal of Cancer (EJC), Jg. 49, 2013, Nr. 9, S. 2107 – 2115
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Assessment of SHOX2 methylation in EBUS-TBNA specimen improves accuracy in lung cancer stagingIn: Annals of Oncology, Jg. 24, 2013, Nr. 11, S. 2866 – 2870
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Bioptische Leberdiagnostik. Was ist wichtig?In: Verdauungskrankheiten, Jg. 31, 2013, Nr. 3, S. 110 – 117
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Controlled oxygenated rewarming of cold stored liver grafts by thermally graduated machine perfusion prior to reperfusionIn: American Journal of Transplantation, Jg. 13, 2013, Nr. 6, S. 1450 – 1460
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Diagnostik der Lungentuberkulose mit Ziehl-Neelsen-Färbung und PolymerasekettenreaktionIn: Der Pathologe, Jg. 34, 2013, Nr. 4, S. 305 – 309
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During Acute Cellular Rejection HLA-E is Expressed in Kidney GraftsIn: Transplant International, Jg. 26, 2013, Nr. Suppl. 1, S. 31 Abstract P17
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ERCC1, MLH1, MSH2, MSH6, and βiII-tubulin: Resistance proteins associated with response and outcome to platinum-based chemotherapy in malignant pleural mesotheliomaIn: Clinical Lung Cancer, Jg. 14, 2013, Nr. 5, S. 558 – 567
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Evaluation of a Novel Endobronchial Ultrasound-Guided Lymph Node Forceps in Enlarged Mediastinal Lymph NodesIn: Respiration: International Journal of Thoracic Medicine, Jg. 86, 2013, Nr. 3, S. 229 – 236
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FFPE tissue as a feasible source for gene expression analysis - A comparison of three reference genes and one tumor markerIn: Pathology, Research and Practice, Jg. 209, 2013, Nr. 12, S. 784 – 789
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Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer CenterIn: European Journal of Cancer (EJC), Jg. 49, 2013, Nr. 15, S. 3076 – 3082
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Fehlbildungen des Ösophagus : Diagnose und TherapieIn: Der Pathologe, Jg. 34, 2013, Nr. 2, S. 94 – 104
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Glanduläres Papillom des rechten Hauptbronchus : Nachweis einer Exon-2-Mutation des KRAS-Gens (c.35G>A)In: Der Pathologe, Jg. 34, 2013, Nr. 4, S. 338 – 342
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Glomerular mRNA expression of prothrombotic and antithrombotic factors in renal transplants with thrombotic microangiopathyIn: Transplantation, Jg. 95, 2013, Nr. 10, S. 1242 – 1248
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Loss of survivin influences liver regeneration and is associated with impaired aurora B functionIn: Cell Death and Differentiation, Jg. 20, 2013, Nr. 6, S. 834 – 844
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Mammalian target of rapamycin pathway activity in alveolar soft part sarcomaIn: Human Pathology, Jg. 44, 2013, Nr. 10, S. 2266 – 2274
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Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexedIn: Journal of Thoracic Oncology, Jg. 8, 2013, Nr. 1, S. 19 – 30
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Chronische Herzinsuffizienz : Partielle Reversibilität durch linksventrikuläre mechanische UnterstützungssystemeIn: Der Pathologe, Jg. 33, 2012, Nr. 3, S. 175 – 182
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Circulating extracellular proteasome in the cerebrospinal fluid : A study on concentration and proteolytic activityIn: Journal of Molecular Neuroscience: JMN online, Jg. 46, 2012, Nr. 3, S. 509 – 515
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Diagnostic approach to interstitial pneumonias in a single centre : report on 88 casesIn: Diagnostic Pathology, Jg. 7, 2012, S. 160DOI, Online Volltext (Open Access)
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Folylpoly-Glutamate Synthetase Expression Is Associated with Tumor Response and Outcome from Pemetrexed-Based Chemotherapy in Malignant Pleural MesotheliomaIn: Journal of Thoracic Oncology, Jg. 7, 2012, Nr. 9, S. 1440 – 1448DOI (Open Access)
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Gene expression signatures differentiate adenocarcinoma of lung and breast origin in effusionsIn: Human Pathology, Jg. 43, 2012, Nr. 5, S. 684 – 694
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Hypothermic reconditioning of porcine kidney grafts by short-term preimplantation machine perfusionIn: Transplantation, Jg. 93, 2012, Nr. 8, S. 787 – 793DOI (Open Access)
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Improvement of histopathological Remission after neoadjuvant chemotherapy of accelerated hyperfractionation compared to conventional fractionation in locally advanced NSCLC (stage III)In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics, Jg. 188, 2012, Nr. Suppl. 1, S. 96 – 96
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Increase of ABCG2/BCRP + side population stem cells in the myocardium after ventricular unloadingIn: Virchows Archiv, Jg. 461, 2012, Nr. Suppl. 1, S. 263
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Increase of ABCG2/BCRP+ side population stem cells in myocardium after ventricular unloadingIn: The Journal of Heart and Lung Transplantation, Jg. 31, 2012, Nr. 3, S. 318 – 324
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Significance of Folate Receptor alpha (FRA) and Thymidylate Synthase (TS) expression in metastatic non-small cell lung cancer patients treated with pemetrexed-based chemotherapyIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 34
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VVTZ-Tumorprofil - First results of a preemptive biomarker profiling program in relation to personalized clinical drug development at a large German Comprehensive Cancer CenterIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 204 – 204
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Βv-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancerIn: British Journal of Cancer (BJC), Jg. 107, 2012, Nr. 5, S. 823 – 830DOI (Open Access)
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„Rapid on-site evaluation“ (ROSE) in der zytologischen Diagnostik von Lungen- und MediastinalerkrankungenIn: Der Pathologe, Jg. 33, 2012, Nr. 4, S. 308 – 315
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Assessment of a chloride-poor versus a chloride-containing version of a modified histidine-tryptophan-ketoglutarate solution in a rat liver transplantation modelIn: Liver Transplantation, Jg. 17, 2011, Nr. 6, S. 650 – 660
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Circulating 20S proteasome in patients with non-metastasized breast cancerIn: Anticancer Research, Jg. 31, 2011, Nr. 6, S. 2197 – 2201(Open Access)
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Clinical, molecular, and genomic changes in response to a left ventricular assist deviceIn: Journal of the American College of Cardiology (JACC), Jg. 57, 2011, Nr. 6, S. 641 – 652DOI (Open Access)
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Evaluation of Betav-Tubulin expression as novel predictive biomarker for clinical benefit from treatment with taxanes in non-small cell lung cancerIn: Journal of Thoracic Oncology, Jg. 6, 2011, Nr. Suppl. 6, S. 1078
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Evaluation of betaV-tubulin expression as novel predictive biomarker for clinical benefit from treatment with taxanes in non-small cell lung cancer (NSCLC)In: European Journal of Cancer (EJC), Jg. 47, 2011, Nr. Suppl. 4, S. 14
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Herztransplantation : Pathologie, Klinik und TherapieIn: Der Pathologe, Jg. 32, 2011, Nr. 2, S. 95 – 103
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Impact of dihydrofolate reductase expression for clinical benefit from pemetrexed in malignant pleural mesotheliomaIn: Journal of Thoracic Oncology, Jg. 6, 2011, Nr. Suppl. 6, S. S1052 – S1053
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Lungentransplantation und Abstoßung : Grundlagen, klinische Aspekte und HistomorphologieIn: Der Pathologe, Jg. 32, 2011, Nr. 2, S. 104 – 112
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Multivisceral systemic metastases from an intracranial anaplastic meningioma : A case report and review of literatureIn: Clinical Neurology and Neurosurgery, Jg. 113, 2011, Nr. 7, S. 592 – 595
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Predictive value of thymidylate synthase and Folypoly-Glutamate Synthease for clinical benefit from pemetrexed in malignant pleural mesotheliomaIn: Journal of Thoracic Oncology, Jg. 6, 2011, Nr. Suppl. 6, S. S1092 – S1093
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Predictive value of thymidylate synthase and folylpoly-glutamate synthetase for clinical benefit from pemetrexed in malignant pleural mesotheliomaIn: Journal of Clinical Oncology (JCO), Jg. 29, 2011, Nr. 15_suppl, S. 7024
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The prognostic impact of circulating proteasome concentrations in patients with epithelial ovarian cancerIn: Gynecologic Oncology, Jg. 120, 2011, Nr. 2, S. 233 – 238
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Basosquamous carcinoma : A rare but aggressive skin malignancyIn: Journal of Plastic, Reconstructive and Aesthetic Surgery (JPRAS), Jg. 63, 2010, Nr. 3, S. e304 – e306
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Cardiomyocyte survivin protein expression is associated with cell size and DNA content in the failing human heart and is reversibly regulated after ventricular unloadingIn: The Journal of Heart and Lung Transplantation, Jg. 29, 2010, Nr. 11, S. 1286 – 1292
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Hemodynamic support by left ventricular assist devices reduces cardiomyocyte DNA content in the failing human heartIn: Circulation, Jg. 121, 2010, Nr. 8, S. 989 – 996
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Neue TNM-klassifikation maligner LungentumorenIn: Der Pathologe, Jg. 31, 2010, Nr. 5, S. 355 – 360
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Reverse remodeling after mechanical left ventricular unloading. Are stem cells involved?In: Fundamental and Clinical Pharmacology, Jg. 24, 2010, Nr. 1
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Reversible regulation of the retinoblastoma protein/E2F-1 pathway during "reverse cardiac remodelling" after ventricular unloadingIn: The Journal of Heart and Lung Transplantation, Jg. 29, 2010, Nr. 1, S. 117 – 124
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Ventricular unloading is associated with increased 20s proteasome protein expression in the myocardiumIn: The Journal of Heart and Lung Transplantation, Jg. 29, 2010, Nr. 1, S. 125 – 132
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Alveolar extracellular 20s proteasome in patients with acute respiratory distress syndromeIn: American Journal of Respiratory and Critical Care Medicine (AJRCCM), Jg. 179, 2009, Nr. 12, S. 1098 – 1106
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Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinomaIn: International Journal of Colorectal Disease, Jg. 24, 2009, Nr. 11, S. 1287 – 1296
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Cyclo-oxygenase-2 overexpression is a feature of early and well-differentiated hepatocellular carcinoma with a favourable prognosisIn: Journal of Clinical Pathology: JCP Online, Jg. 62, 2009, Nr. 8, S. 690 – 693
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Differential expression of microRNA 181b and microRNA 21 in hyperplastic polyps and sessile serrated adenomas of the colonIn: Virchows Archiv, Jg. 455, 2009, Nr. 1, S. 49 – 54
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Evaluation of a modified HTK solution containing the new iron chelator LK 614 in an isolated rat liver perfusion modelIn: Journal of Investigative Surgery, Jg. 22, 2009, Nr. 5, S. 340 – 347
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Immunocytochemical investigation of Langerin (CD207) is a valuable adjunct in the cytological diagnosis of Langerhans cell histiocytosis of the thyroidIn: Pathology, Research and Practice, Jg. 205, 2009, Nr. 6, S. 433 – 436
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Metallothionein overexpression and its prognostic relevance in intrahepatic cholangiocarcinoma and extrahepatic hilar cholangiocarcinoma (Klatskin tumors)In: Human Pathology, Jg. 40, 2009, Nr. 12, S. 1706 – 1714
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Phosphorylation of p70S6 kinase predicts overall survival in patients with clear margin-resected hepatocellular carcinomaIn: Liver International, Jg. 29, 2009, Nr. 3, S. 399 – 405
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R0 liver resections for primary malignant liver tumors in the noncirrhotic liver : A diagnosis-related analysisIn: Digestive Diseases and Sciences, Jg. 54, 2009, Nr. 4, S. 887 – 894
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Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferationIn: Liver International, Jg. 29, 2009, Nr. 4, S. 585 – 592
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White matter changes in HIV-1 infected brains : A combined gross anatomical and ultrastructural morphometric investigation of the corpus callosumIn: Clinical Neurology and Neurosurgery, Jg. 111, 2009, Nr. 5, S. 422 – 429
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Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infectionIn: Journal of Hepatology, Jg. 48, 2008, Nr. 1, S. 83 – 90
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Decreased Myocardial Chromogranin A Expression and Colocalization With Brain Natriuretic Peptide During Reverse Cardiac Remodeling After Ventricular UnloadingIn: The Journal of Heart and Lung Transplantation, Jg. 27, 2008, Nr. 4, S. 442 – 449
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Erythropoietin treatment improves liver regeneration and survival in rat models of extended liver resection and living donor liver transplantationIn: Transplantation, Jg. 86, 2008, Nr. 11, S. 1578 – 1585
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Five-Year Survival After Monotherapy for Hepatocellular Carcinoma in the Setting of CirrhosisIn: Transplantation Proceedings, Jg. 40, 2008, Nr. 9, S. 3204 – 3205
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Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overloadIn: Cardiovascular Research, Jg. 79, 2008, Nr. 3, S. 464 – 471DOI (Open Access)
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Role of Osteopontin and CD44s Expression for Patients With Hepatocellular Carcinoma Undergoing Liver Transplantation or ResectionIn: Transplantation Proceedings, Jg. 40, 2008, Nr. 9, S. 3182 – 3184
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Survivin determines cardiac function by controlling total cardiomyocyte numberIn: Circulation, Jg. 117, 2008, Nr. 12, S. 1583 – 1593
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AKT and ERK1/2 signaling in intrahepatic cholangiocarcinomaIn: World Journal of Gastroenterology, Jg. 13, 2007, Nr. 48, S. 6470
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Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutationsIn: Virchows Archiv, Jg. 450, 2007, Nr. 2, S. 151 – 159
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Elevated expression of cyclooxygenase-2 is a negative prognostic factor for overall survival in intrahepatic cholangiocarcinomaIn: Virchows Archiv, Jg. 450, 2007, Nr. 2, S. 135 – 141DOI (Open Access)
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GNAS1 T393C polymorphism is associated with clinical course in patients with intrahepatic cholangiocarcinomaIn: Neoplasia: An International Journal for Oncology Research, Jg. 9, 2007, Nr. 2, S. 159 – 165DOI (Open Access)
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Prevalence of human papillomavirus DNA in cholesteatomasIn: ORL, Jg. 69, 2007, Nr. 4, S. 251 – 255
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Roles of cyclooxygenase-2 and phosphorylated Akt ⁽Thr³⁰⁸⁾ in cardiac hypertrophy regression mediated by left-ventricular unloadingIn: Journal of Thoracic and Cardiovascular Surgery, Jg. 133, 2007, Nr. 1, S. 37 – 43DOI (Open Access)
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Chirurgische Therapie des intrahepatischen cholangiozellulären KarzinomsIn: Der Chirurg, Jg. 77, 2006, Nr. 1, S. 53 – 60
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Degraded collagen induces calpain-mediated apoptosis and destruction of the X-chromosome-linked inhibitor of apoptosis (xIAP) in human vascular smooth muscle cellsIn: Cardiovascular Research, Jg. 69, 2006, Nr. 3, S. 697 – 705DOI (Open Access)
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No association of the NFKB1 insertion/deletion promoter polymorphism with survival in colorectal and renal cell carcinoma as well as disease progression in B-cell chronic lymphocytic leukemiaIn: Pharmacogenetics and Genomics, Jg. 16, 2006, Nr. 11, S. 783 – 788
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Overexpression of cyclo-oxygenase-2 is an independent predictor of unfavourable outcome in node-negative breast cancer, but is not associated with protein kinase B (Akt) and mitogen-activated protein kinase (ERK1/2, p38) activation or with Her-2/neu signalling pathwaysIn: Journal of Clinical Pathology: JCP Online, Jg. 59, 2006, Nr. 7, S. 685 – 691DOI (Open Access)
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Relationship and prognostic significance of phospho-(serine 166)-murine double minute 2 and Akt activation in node-negative breast cancer with regard to p53 expressionIn: Virchows Archiv, Jg. 448, 2006, Nr. 1, S. 16 – 23
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GNAS1 T393C polymorphism and survival in patients with sporadic colorectal cancerIn: Clinical Cancer Research, Jg. 11, 2005, Nr. 14, S. 5071 – 5077DOI (Open Access)
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High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome.In: Breast Cancer Research : BCR, Jg. 7, 2005, Nr. 2DOI (Open Access)
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Identification of Chlamydia pneumoniae in intracranial and extracranial arteries in patients with stroke and in controls : Combined immunohistochemical and polymerase chain reaction analysesIn: Human Pathology, Jg. 36, 2005, Nr. 4, S. 395 – 402
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Immunohistochemical differentiation of eosinophilic heart diseases using antibodies against eosinophil activation markersIn: Histopathology, Jg. 46, 2005, Nr. 1, S. 89 – 97
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Reverse remodeling following insertion of left ventricular assist devices (LVAD) : A review of the morphological and molecular changesIn: Cardiovascular Research, Jg. 68, 2005, Nr. 3, S. 376 – 386DOI (Open Access)
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Roles of MMP-2/-9 in cardiac dysfunction during early multiple organ failure in an ovine animal modelIn: Pathology, Research and Practice, Jg. 201, 2005, Nr. 12, S. 809 – 817
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Heat shock protein 72 and apoptosis indicate cardiac decompensation during early multiple organ failure in sheepIn: Intensive Care Medicine, Jg. 30, 2004, Nr. 7, S. 1405 – 1413
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Pathologie des Herz-Kreislauf-SystemsIn: Der Pathologe. Heidelberg; Berlin; Heidelberg [u.a.]: Springer Medizin, Jg. 33, 2012, Nr. 3, S. 173 – 174
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Defects in Homologous Recombination Repair Indicates Susceptibility for Olaparib Treatment in Malignant Pleural MesotheliomaIn: Journal of Thoracic Oncology. Amsterdam: Elsevier, Jg. 14, 2019, Nr. 10, Supplement, S. S482DOI (Open Access)
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Immunohistochemically Detectable Metallothionein Expression in Malignant Pleural Mesotheliomas is Strongly Associated with Early Failure to Platin-Based Chemotherapy
Herbsttagung der Sektion Zellbiologie in der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V., Essen, 09.–10.11.2018,In: Pneumologie. Stuttgart: Thieme, Jg. 73, 2019, Nr. 02, S. 110 – 111 -
Influence of Methallothionein Expression on Sensitivity Against Platin Compounds in Human Malignant Pleural Mesothelioma Cell Lines – Knock-Down of Gene Expression as New Therapeutic Approach?
Herbsttagung der Sektion Zellbiologie in der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V., Essen, 09.–10.11.2018,In: Pneumologie. Stuttgart: Thieme, Jg. 73, 2019, Nr. 02, S. 115 -
BRCAness phenotype is common in MPM and is associated with response to olaparib in vitro
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 1, S. 175DOI (Open Access) -
Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 1, S. 115DOI (Open Access) -
Inhibition of MDM2 via Nutlin-3A : A potential therapeutic approach for pleural mesotheliomas with MDM2-induced inactivation of P53
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 1, S. 175DOI (Open Access) -
Mass Spectrometry based Methylation Analysis of MDM2, CDKN2A, RB1, TP53 and TP73 and Associations to MDM2 Overexpression in Malignant Pleural mesothelioma
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 1, S. 115DOI (Open Access) -
Processing escape mechanisms through alterated proteasomal cleavage of epitopes affects immune response in pulmonary neuroendocrine tumors
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 1, S. 176DOI (Open Access) -
Identification of prognostic and predictive biomarkers in malignant pleural mesothelioma in 134 patients from two research sites (Berlin and Essen)
Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 123 -
Rekursive Partitions-Analyse prognostischer Faktoren für das Langzeit-Überleben nach trimodaler Therapie von Patienten mit lokal fortgeschrittenem NSCLC
21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 191, 2015, Nr. Suppl. 1, S. 23 -
HLA-E expression and its impact on renal transplant outcome
28th EFI European Immunogenetics and Histocompatibility Conference Stockholm, Sweden, June 25th–28th, 2014,In: Tissue Antigens. Oxford: Wiley-Blackwell, Jg. 84, 2014, Nr. 1, S. 24 -
Prognostisches Modell für das Langzeit-Überleben von Patienten mit lokal fortgeschrittenem nicht-kleinzelligen Lungenkarzinom (NSCLC) nach neoadjuvanter Radiochemotherapie (RT/CT) und Resektion
20. Jahreskongress der Deutschen Gesellschaft für Radioonkologie (DEGRO), 3. bis 6. Juli 2014, Düsseldorf,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 190, 2014, Nr. Suppl 1, S. 17 -
Proktitiden mit N. gonorrhoeae/C. trachomatis führen zur Rekrutierung von HIV-Zielzellen aber nicht zu einer gesteigerten HIV-Sekretion
Leopoldina-Symposium und STI-Kongress, 18. und 19.–21. Juni 2014, Berlin,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 12, 2014, Nr. 10, S. 952 – 953 -
Vergleich von pCR und mediastinalem Downstaging als Surrogat- Marker für das Langzeit-Überleben von Patienten mit lokal fortgeschrittenem nicht-kleinzelligen Lungenkarzinom (NSCLC) nach neoadjuvanter Radiochemotherapie (RT/CT) und Resektion (Trimodalität)
20. Jahreskongress der Deutschen Gesellschaft für Radioonkologie (DEGRO), 3. bis 6. Juli 2014, Düsseldorf,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 190, 2014, Nr. Suppl. 1, S. 17 -
WTZ-Tumorprofil-A preemptive biomarker profiling program in relation to personalized clinical drug development at a large German Comprehensive Cancer Center : Two years experience
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin, Germany,In: Oncology Research and Treatment. Basel: Karger, Jg. 37, 2014, Nr. Suppl. 1, S. 2 – 3 -
Akzeleriert-hyperfraktionierte Radiotherapie (RTx) mit simultaner Chemotherapie (CTx) im neoadjuvanten Konzept bei Stadium-III Lungenkarzinom : signifikant höhere Rate pathologisch kompletter Remissionen (pCR) im Vergleich mit konventioneller Fraktionierung
19. Jahreskongress der Deutschen Gesellschaft für Radioonkologie Berlin, 9. bis 12. Mai 2013,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 189, 2013, Nr. Suppl. 1, S. 19 -
Folylpoly-α-glutamate synthetase and thymidylate synthase are associated with clinical outcome from pemetrexed-based therapy in advanced non-small cell lung cancer (NSCLC)In: Cancer Research. Philadelphia: American Association for Cancer Research (AACR), Jg. 72, 2012, Nr. 8, Suppl., S. 1713
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Competing risks analysis and long-term survival (LTS) of patients (PTS) with locally advanced (LAD) stage III non-small- cell lung cancer (NSCLC) treated on sequential trimodality (TM) trials
14th World Conference on Lung Cancer (WCLC), July 03 - 07, 2011, Amsterdam, The Netherlands,In: Journal of Thoracic Oncology. Amsterdam: Elsevier, Jg. 6, 2011, Nr. 6, Suppl. 2, S. S376 – S377 -
Aspekte der akuten und chronischen Herzinsuffizienz unter besonderer Berücksichtigung des „reverse cardiac remodelling“ nach Kunstherztherapie durch linksventrikuläre Unterstützungssysteme (LVAD)Universität Duisburg-Essen, 2009