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Universitätsprofessor/in, Institut für Anatomie
Aktuelle Veranstaltungen
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2024 WS
- Vorlesung Makroskopische Anatomie (1. FS) (Osteologie, passiver Bewegungsapparat, Propädeutik)
- Wahlfach: Entwicklungsbiologie des Nervensystems (3.FS)
- Seminar Anatomie (Neuroanatomie) (3.FS)
- Begleitvorlesung zum Seminar Anatomie (Neuroanatomie, 3. FS)
- Retinopathien und Mechanismen der retinalen Proliferations- und Apoptosekontrolle
- Modern Biomedicine/Beispiele biologischer Forschung (Teil 1)
- Anleitung zum wissenschaftlichen Arbeiten
- Anatomie 1: Vorlesung Makroskopische Anatomie (Osteologie, passiver Bewegungsapparat) für Medizintechniker
Vergangene Veranstaltungen (max. 10)
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2024 SS
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2023 WS
- Vorlesung Makroskopische Anatomie (1. FS) (Osteologie, passiver Bewegungsapparat, Propädeutik)
- Begleitvorlesung zum Seminar Anatomie (Neuroanatomie, 3. FS)
- Wahlfach: Entwicklungsbiologie des Nervensystems (3.FS)
- Seminar Anatomie (Neuroanatomie) (3.FS)
- Retinopathien und Mechanismen der retinalen Proliferations- und Apoptosekontrolle
- Anleitung zum wissenschaftlichen Arbeiten
- Modern Biomedicine/Beispiele biologischer Forschung (Teil 1)
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stabilityIn: Journal of Controlled Release Jg. 373 (2024) S. 583 - 598Online Volltext: dx.doi.org/ (Open Access)
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Gastric Inhibitory Polypeptide Receptor (GIPR) Overexpression Reduces the Tumorigenic Potential of Retinoblastoma CellsIn: Cancers Jg. 16 (2024) Nr. 9, 1656Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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In vitro model of retinoblastoma derived tumor and stromal cells for tumor microenvironment (TME) studiesIn: Cell Death and Disease Jg. 15 (2024) Nr. 12, 905Online Volltext: dx.doi.org/ (Open Access)
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New retinoblastoma (RB) drug delivery approaches : anti-tumor effect of atrial natriuretic peptide (ANP)-conjugated hyaluronic-acid-coated gold nanoparticles for intraocular treatment of chemoresistant RBIn: Molecular Oncology Jg. 18 (2024) Nr. 4, S. 832 - 849Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Role of Protein Tyrosine Phosphatase Receptor Type E (PTPRE) in Chemoresistant RetinoblastomaIn: International Journal of Molecular Sciences (IJMS) Jg. 25 (2024) Nr. 8, 4572Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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α-Ketoglutarate supplementation and NAD+ modulation enhance metabolic rewiring and radiosensitization in SLC25A1 inhibited cancer cellsIn: Cell Death Discovery Jg. 10 (2024) Nr. 1, 27Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Evaluation of the Effect of Photodynamic Therapy on CAM-Grown SarcomasIn: Bioengineering Jg. 10 (2023) Nr. 4, 464Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma : Pro-Angiogenesis through Paracrine PAI-1 and IL-8In: Cancers Jg. 15 (2023) Nr. 17, 4422Online Volltext: dx.doi.org/ (Open Access)
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Trefoil Family Factor Peptide 1 : A New Biomarker in Liquid Biopsies of Retinoblastoma under TherapyIn: Cancers Jg. 15 (2023) Nr. 19, 4828Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Tumor Suppressor Role of INPP4B in Chemoresistant RetinoblastomaIn: Journal of Oncology (2023) 2270097Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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5-ALA-mediated fluorescence of musculoskeletal tumors in a chick chorio-allantoic membrane model : Preclinical in vivo qualification analysis as a fluorescence-guided surgery agent in Orthopedic OncologyIn: Journal of Orthopaedic Surgery and Research Jg. 17 (2022) Nr. 1, 34Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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ADAM10 and ADAM17 : Novel Players in Retinoblastoma CarcinogenesisIn: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 20, 12621Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Retinoblastoma Cell Growth 'In Vitro' and Tumor Formation 'In Ovo' : Influence of Different Culture ConditionsIn: Methods and Protocols Jg. 5 (2022) Nr. 2, 21Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Role of L1CAM in retinoblastoma tumorigenesis : identification of novel therapeutic targetsIn: Molecular Oncology Jg. 16 (2022) Nr. 4,Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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TFF1 in Aqueous Humor : A Potential New Biomarker for RetinoblastomaIn: Cancers Jg. 14 (2022) Nr. 3, 677Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Impact of RARα and miR-138 on retinoblastoma etoposide resistanceIn: Tumor Biology Jg. 43 (2021) Nr. 1, S. 11 - 26Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery : Evaluation of the surface properties and effect on their distributionIn: Experimental Eye Research Jg. 198 (2020) 108151Online Volltext: dx.doi.org/ (Open Access)
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Implementation of the chick chorioallantoic membrane (CAM) model in radiation biology and experimental radiation oncology researchIn: Cancers Jg. 11 (2019) Nr. 10, S. 1499Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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p53, miR-34a and EMP1 : Newly Identified Targets of TFF3 Signaling in Y79 Retinoblastoma CellsIn: International Journal of Molecular Sciences (IJMS) Jg. 20 (2019) Nr. 17, S. 4129Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Characterization of etoposide- and cisplatin-chemoresistant retinoblastoma cell linesIn: Oncology Reports Jg. 39 (2018) Nr. 1, S. 160 - 172Online Volltext: dx.doi.org/ (Open Access)
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Trefoil factor family 1 expression correlates with clinical outcome in petients withr retinoblastomaIn: Retina Jg. 38 (2018) Nr. 12, S. 2422 - 2428Online Volltext: dx.doi.org/
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Reduction of the tumorigenic potential of human retinoblastoma cell lines by TFF1 overexpression involves p53/caspase signaling and miR-18a regulationIn: International Journal of Cancer Jg. 141 (2017) Nr. 3, S. 549 - 560Online Volltext: dx.doi.org/
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Forced Trefoil Factor Family Peptide 3 (TFF3) Expression Reduces Growth, Viability, and Tumorigenicity of Human Retinoblastoma Cell LinesIn: PLoS ONE Jg. 11 (2016) Nr. 9, S. 0163025Online Volltext: dx.doi.org/ (Open Access)
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Additive effects of retinoic acid (RA) and bone morphogenetic protein 4 (BMP-4) apoptosis signaling in retinoblastoma cell linesIn: PLoS ONE Jg. 10 (2015) Nr. 7,Online Volltext: dx.doi.org/ (Open Access)
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Re-characterization of established human retinoblastoma cell linesIn: Histochemistry and Cell Biology Jg. 143 (2015) Nr. 3, S. 325 - 338Online Volltext: dx.doi.org/
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Trefoil factor family peptides : Friends or foes?In: Biomolecular Concepts Jg. 6 (2015) Nr. 5-6, S. 343 - 359Online Volltext: dx.doi.org/
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Epigenetic control of trefoil factor family (TFF) peptide expression in human retinoblastoma cell linesIn: Cellular Physiology and Biochemistry Jg. 34 (2014) Nr. 3, S. 1001 - 1014Online Volltext: dx.doi.org/ (Open Access)
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High trefoil factor 1 (TFF1) expression in human retinoblastoma cells correlates with low growth kinetics, increased cyclin-dependent kinase (CDK) inhibitor levels and a selective down-regulation of CDK6In: Histochemistry and Cell Biology Jg. 139 (2013) Nr. 2, S. 323 - 338Online Volltext: dx.doi.org/
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Loss at chromosome arm 16q in retinoblastoma : confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted regionIn: Genes, Chromosomes and Cancer Jg. 50 (2011) Nr. 5, S. 327 - 337Online Volltext: dx.doi.org/
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Trefoil factor family peptide 2 acts pro-proliferative and pro-apoptotic in the murine retina.In: Histochemistry and Cell Biology Jg. 135 (2011) Nr. 5, S. 461 - 473Online Volltext: dx.doi.org/
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Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cellsIn: International Journal of Biological Sciences Jg. 6 (2010) Nr. 7, S. 700 - 715Online Volltext: dx.doi.org/ (Open Access)
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Chick ex ovo culture and ex ovo CAM assay : How it really worksIn: JoVE (2010) Nr. 33, S. e1620Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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In vivo-like Organotypic Murine Retinal Wholemount CultureIn: JoVE (2010) Nr. 35, S. e1634Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The anemia of the newborn induces erythropoietin expression in the developing mouse retinaIn: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology Jg. 299 (2010) Nr. 1, S. R111 - R118Online Volltext: dx.doi.org/
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Recruitment and maintenance of tendon progenitors by TGFβ signaling are essential for tendon formationIn: Development / Company of Biologists Jg. 136 (2009) Nr. 8, S. 1351 - 1361Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Transforming growth factor beta mediates apoptosis in the ganglion cell layer during all programmed cell death periods of the developing murine retinaIn: Neuroscience Research Jg. 56 (2006) Nr. 2, S. 193 - 203Online Volltext: dx.doi.org/
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Transforming growth factor β is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo : Ectopic induction in dorsal mesencephalonIn: Stem Cells Jg. 24 (2006) Nr. 9, S. 2120 - 2129Online Volltext: dx.doi.org/ (Open Access)
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Transforming growth factor-β and bone morphogenetic proteins: Cooperative players in chick and murine programmed retinal cell deathIn: The Journal of Comparative Neurology Jg. 495 (2006) Nr. 3, S. 263 - 278Online Volltext: dx.doi.org/
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Balance of pro-apoptotic transforming growth factor-β and anti-apoptotic insulin effects in the control of cell death in the postnatal mouse retinaIn: European Journal of Neuroscience Jg. 22 (2005) Nr. 1, S. 28 - 38Online Volltext: dx.doi.org/
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Transforming growth factor-β (TGF-β) and programmed cell death in the vertebrate retinaIn: International Review of Cytology Jg. 245 (2005) S. 17 - 43Online Volltext: dx.doi.org/
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Isoform-specific role of transforming growth factor-β2 in the regulation of proliferation and differentiation of murine adrenal chromaffin cells in vivoIn: Journal of Neuroscience Research Jg. 78 (2004) Nr. 4, S. 493 - 498Online Volltext: dx.doi.org/
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Immunohistochemical evaluation of matrix molecules associated with wound healing following treatment with an enamel matrix protein derivative in humansIn: Clinical Oral Investigations Jg. 7 (2003) Nr. 3, S. 167 - 174Online Volltext: dx.doi.org/
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Reduced programmed cell death in the retina and defects in lens and cornea of Tgfβ2 –/– Tgfβ3 –/– double-deficient miceIn: Cell and Tissue Research Jg. 313 (2003) Nr. 1, S. 1 - 10Online Volltext: dx.doi.org/
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Transforming Growth Factor-βs Are Essential for the Development of Midbrain Dopaminergic NeuronsIn VitroandIn VivoIn: The Journal of Neuroscience Jg. 23 (2003) Nr. 12, S. 5178 - 5186Online Volltext: dx.doi.org/ (Open Access)
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Transforming growth factor beta mediated programmed cell death in tissue regeneration of the murine intestinal mucosa.In: Annals of Anatomy Jg. 185 (2003) Nr. 4, S. 299 - 300Online Volltext: dx.doi.org/
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Transforming growth factor-β and tumor necrosis factor-α cooperate to induce apoptosis in the oligodendroglial cell line OLI-neuIn: Journal of Neuroscience Research Jg. 73 (2003) Nr. 3, S. 324 - 333Online Volltext: dx.doi.org/
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Immunohistochemical evaluation of matrix molecules associated with wound healing following regenerative periodontal treatment in monkeysIn: Clinical Oral Investigations Jg. 6 (2002) Nr. 3, S. 175 - 182Online Volltext: dx.doi.org/
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TGF-β is required for programmed cell death in interdigital webs of the developing mouse limbIn: Mechanisms of Development Jg. 113 (2002) Nr. 2, S. 111 - 120Online Volltext: dx.doi.org/ (Open Access)
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Tgfβ2⁻/⁻Tgfβ3⁻/⁻ double knockout mice display severe midline fusion defects and early embryonic lethalityIn: Anatomy and Embryology Jg. 206 (2002) Nr. 1-2, S. 73 - 83Online Volltext: dx.doi.org/
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The role of transforming growth factor beta-2, beta-3 in mediating apoptosis in the murine intestinal mucosaIn: Gastroenterology Jg. 122 (2002) Nr. 5, S. 1364 - 1375Online Volltext: dx.doi.org/
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Transforming growth factor-beta 2 heterozygous mutant mice exhibit Cowper's gland hyperplasia and cystic dilations of the gland ducts (Cowper's syringoceles)In: Journal of Anatomy Jg. 201 (2002) Nr. 2, S. 173 - 183Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Transforming growth factor-β induced cell death in the developing chick retina is mediated via activation of c-jun N-terminal kinase and downregulation of the anti-apoptotic protein Bcl-XLIn: Neuroscience Letters Jg. 330 (2002) Nr. 3, S. 239 - 242Online Volltext: dx.doi.org/
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TGF-beta modulates programmed cell death in the retina of the developing chick embryo.In: Development Jg. 128 (2001) Nr. 11, S. 1933 - 1942
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Embryonic and larval development in the caecilian Ichthyophis kohtaoensis (Amphibia, gymnophiona) : a staging tableIn: Journal of morphology Jg. 243 (2000) Nr. 1, S. 3 - 34Online Volltext: dx.doi.org/
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Reduction of endogenous transforming growth factors β prevents ontogenetic neuron deathIn: Nature Neuroscience Jg. 3 (2000) Nr. 11, S. 1085 - 1090Online Volltext: dx.doi.org/
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Targeted mutations of transforming growth factor-β genes reveal important roles in mouse development and adult homeostasisIn: EJB: the FEBS journal Jg. 267 (2000) Nr. 24, S. 6982 - 6988Online Volltext: dx.doi.org/
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Serotonergic neurons and processes in the adult and developing retina of Ichthyophis kohtaoensis (Amphibia; Gymnophiona)In: Anatomy and Embryology Jg. 199 (1999) Nr. 1, S. 35 - 43Online Volltext: dx.doi.org/
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A double-label analysis demonstrating the partial coexistence of tyrosine hydroxylase and GABA in retinal neurons of Ichthyophis kohtaoensis (Amphibia; Gymnophiona)In: Cell and Tissue Research Jg. 294 (1998) Nr. 2, S. 387 - 390Online Volltext: dx.doi.org/
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Colocalization of serotonin and GABA in retinal neurons of Ichthyophis kohtaoensis (amphibia; Gymnophiona)In: Anatomy and embryology Jg. 197 (1998) Nr. 1, S. 69 - 75
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Development and organization of the retinal dopaminergic system of Ichthyophis kohtaoensis (Amphibia; Gymnophiona)In: Cell and Tissue Research Jg. 289 (1997) Nr. 2, S. 265 - 274Online Volltext: dx.doi.org/
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Correlation of neurotrophin expression and survival-promoting capacities with different programmed cell death periods in the developing murine retinaIn: Neuroanatomy Research Advances / Callaghan, Brandon R.; Flynn, Cian E. (Hrsg.) 2010, S. 93 - 120
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How to deal with (cross)-resistant retinoblastoma cells
114. Jahrestagung / 33. Arbeitstagung der Anatomischen Gesellschaft, Würzburg, 25.-27.09.2019,Würzburg (2019)