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apl. Professor/in und Privatdozent/in, Institut für Zellbiologie (Tumorforschung)
Aktuelle Veranstaltungen
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2023 SS
- Praktikum Zell- und Molekularbiologie für med. Biologen (Bachelor) (PV)
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe I
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe II
- Neue Literatur der Zell- und Molekularbiologie für Med. Biologen
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Mitarbeiterseminar zur Besprechung aktueller Arbeiten
Vergangene Veranstaltungen (max. 10)
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2022 WS
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Mitarbeiterseminar zur Besprechung aktueller Arbeiten
- Laborpraktikum II für Masterstudenten der medizinischen Biologie (WP)
- Laborpraktikum I für Masterstudenten der medizinischen Biologie (WP)
- Laborpraktikum III für Masterstudenten der medizinischen Biologie (WP)
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2022 SS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancingIn: Brain, Behavior and Immunity Jg. 100 (2022) S. 134 - 144ISSN: 1090-2139; 0889-1591Online Volltext: dx.doi.org/ (Open Access)
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Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain InjuryIn: Stroke Jg. 53 (2022) Nr. 2, S. 381 - 390ISSN: 1524-4628; 0039-2499Online Volltext: dx.doi.org/ (Open Access)
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TLR2-induced CD8⁺ T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsisIn: Frontiers in Immunology Jg. 13 (2022)ISSN: 1664-3224Online Volltext: dx.doi.org/ (Open Access)
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A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of HypoxiaIn: Frontiers in Cellular and Infection Microbiology Jg. 11 (2021) S. 639620ISSN: 2235-2988Online Volltext: dx.doi.org/ (Open Access)
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Acute myeloid leukemia–induced remodeling of the human bone marrow niche predicts clinical outcomeIn: Blood Advances Jg. 4 (2020) Nr. 20, S. 5257 - 5268ISSN: 2473-9537; 2473-9529Online Volltext: dx.doi.org/ (Open Access)
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Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemiaIn: Therapeutic Advances in Hematology Jg. 11 (2020) S. 1 - 15ISSN: 2040-6207; 2040-6215Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiomeIn: Immunology Jg. 159 (2020) Nr. 3, S. 344 - 353ISSN: 1365-2567; 0019-2805Online Volltext: dx.doi.org/ (Open Access)
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Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencingIn: Cancers Jg. 12 (2020) Nr. 4, S. 986ISSN: 2072-6694Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Molecular Mechanisms in the Pathogenesis of Composite LymphomasIn: Klinische Pädiatrie Jg. 232 (2020) Nr. 02, S. 80ISSN: 1439-3824; 0300-8630Online Volltext: dx.doi.org/
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Mutations in PIGA cause a CD52-/GPI-anchor-deficient phenotype complicating alemtuzumab treatment in T-cell prolymphocytic leukemiaIn: European Journal of Haematology Jg. 105 (2020) Nr. 6, S. 786 - 796ISSN: 1600-0609; 0902-4441; 0036-553XOnline Volltext: dx.doi.org/ (Open Access)
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Targeted bisulfite sequencing : A novel tool for the assessment of DNA methylation with high sensitivity and increased coverageIn: Psychoneuroendocrinology Jg. 120 (2020)ISSN: 1873-3360; 0306-4530Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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Genome-wide analysis of the nucleosome landscape in individuals with coffin-siris syndromeIn: Cytogenetic and Genome Research Jg. 159 (2019) S. 1 - 11ISSN: 1424-859X; 1424-8581Online Volltext: dx.doi.org/ (Open Access)
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Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases (JID) Jg. 219 (2019) Nr. 3, S. 497 - 508ISSN: 0022-1899; 1537-6613Online Volltext: dx.doi.org/ (Open Access)
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Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohortIn: Acta Neuropathologica Communications Jg. 7 (2019) Nr. 1, S. 181ISSN: 2051-5960Online Volltext: dx.doi.org/ (Open Access)
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An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphomaIn: Leukemia Jg. 32 (2018) Nr. 1, S. 92 - 101ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood Jg. 131 (2018) Nr. 5, S. 546 - 557ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/ (Open Access)
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Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemiaIn: Nature Communications Jg. 9 (2018) S. 3839ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access)
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SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemiaIn: Blood Cancer Journal Jg. 8 (2018) Nr. 1, S. 11ISSN: 2044-5385Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A novel physiological role for cardiac myoglobin in lipid metabolismIn: Scientific Reports Jg. 7 (2017) S. 43219ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access)
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Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesionsIn: Nature Communications Jg. 8 (2017)ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access)
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Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7In: Gut Pathogens Jg. 9 (2017) S. 30ISSN: 1757-4749Online Volltext: dx.doi.org/ (Open Access)
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Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileusIn: Gut Jg. 66 (2017) Nr. 12, S. 2110 - 2120ISSN: 1468-3288; 0017-5749Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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NOTCH-signaling in the tumor microenvironment is required for canonical WNT signaling in CLL cellsIn: Leukemia and Lymphoma Jg. 58 (2017) Nr. Suppl. 1, XVII International Workshop on Chronic Lymphocytic Leukemia 2017 May 12--15, 2017, New York, S. 125 - 126ISSN: 1042-8194; 1029-2403Online Volltext: dx.doi.org/
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Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivoIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 114 (2017) Nr. 52, S. E11323 - E11332ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/
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OTX2 defines a subgroup of atypical teratoid rhabdoid tumors with close relationship to choroid plexus tumorsIn: Journal of Neuropathology and Experimental Neurology Jg. 76 (2017) Nr. 1, S. 32 - 38ISSN: 1554-6578; 0022-3069Online Volltext: dx.doi.org/ (Open Access)
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Regions of common inter-individual DNA methylation differences in human monocytes: Genetic basis and potential functionIn: Epigenetics and Chromatin Jg. 10 (2017) Nr. 1, S. 37ISSN: 1756-8935Online Volltext: dx.doi.org/ (Open Access)
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The lung microbiome in patients with pneumocystosisIn: BMC Pulmonary Medicine Jg. 17 (2017) Nr. 1, S. 170ISSN: 1471-2466Online Volltext: dx.doi.org/ (Open Access)
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A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2AIn: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 101 (2016) Nr. 3, S. 1016 - 1022ISSN: 0021-972X; 1945-7197Online Volltext: dx.doi.org/ (Open Access)
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Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cellsIn: OncoTarget Jg. 7 (2016) Nr. 46, S. 74415 - 74426ISSN: 1949-2553Online Volltext: dx.doi.org/ (Open Access)
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Epigenetic dynamics of monocyte-to-macrophage differentiationIn: Epigenetics and Chromatin Jg. 9 (2016) S. 33ISSN: 1756-8935Online Volltext: dx.doi.org/ (Open Access)
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GFI1 as a novel prognostic and therapeutic factor for AML/MDSIn: Leukemia Jg. 30 (2016) Nr. 6, S. 1237 - 1245ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinomaIn: The Journal of Clinical Investigation (JCI) Jg. 126 (2016) Nr. 11, S. 4187 - 4204ISSN: 1558-8238; 0021-9738Online Volltext: dx.doi.org/
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Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemiaIn: International Journal of Cancer Jg. 138 (2016) Nr. 1, S. 121 - 124ISSN: 0020-7136; 1097-0215Online Volltext: dx.doi.org/ (Open Access)
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Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomasIn: OncoTarget Jg. 7 (2016) Nr. 38, S. 62627 - 62639ISSN: 1949-2553Online Volltext: dx.doi.org/ (Open Access)
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Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemiaIn: Leukemia and Lymphoma Jg. 57 (2016) Nr. 3, S. 590 - 595ISSN: 1029-2403Online Volltext: dx.doi.org/
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A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studiesIn: Oncogene Jg. 34 (2015) Nr. 26, S. 3357 - 3368ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ (Open Access)
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Absence of telomerase reverse transcriptase promoter mutations in neuroblastomaIn: Biomedical Reports Jg. 3 (2015) Nr. 4, S. 443 - 446ISSN: 2162-4178; 2049-9442Online Volltext: dx.doi.org/
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BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activityIn: Blood Jg. 125 (2015) Nr. 8, S. 1207 - 1216ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/ (Open Access)
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Characterization of bursa subacromialis-derived mesenchymal stem cellsIn: Stem Cell Research & Therapy Jg. 6 (2015) S. 114ISSN: 1757-6512Online Volltext: dx.doi.org/ (Open Access)
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Endothelial cells isolated from colorectal carcinoma exhibit tumor microenvironment-dependent plasticity allowing the identification of SPARCL1 as a novel endothelial cell quiescence factorIn: Cancer Research Jg. 75 (2015) Nr. 15 Suppl., S. 2375ISSN: 0008-5472Online Volltext: dx.doi.org/
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Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 ExpressionIn: PLoS ONE Jg. 10 (2015) Nr. 9, S. e0137043ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Functional abnormalities and changes in gene expression in fibroblasts and macrophages from the bone marrow of patients with acute myeloid leukemiaIn: International Journal of Hematology Jg. 102 (2015) Nr. 3, S. 278 - 288ISSN: 1865-3774; 0925-5710Online Volltext: dx.doi.org/
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High-Resolution Genomic Analysis Does Not Qualify Atypical Plexus Papilloma as a Separate Entity Among Choroid Plexus TumorsIn: Journal of Neuropathology and Experimental Neurology Jg. 74 (2015) Nr. 2, S. 110 - 120ISSN: 0022-3069; 1554-6578Online Volltext: dx.doi.org/ (Open Access)
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Interference of peritoneal dialysis fluids with cell cycle mechanismsIn: Peritoneal Dialysis International Jg. 35 (2015) Nr. 3, S. 259 - 274ISSN: 0896-8608Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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N6-Adenosine Methylation in MiRNAsIn: PLoS ONE Jg. 10 (2015) Nr. 2, S. e0118438ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell lineIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 79 (2015) S. 150 - 161ISSN: 1873-2763; 8756-3282Online Volltext: dx.doi.org/
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Pro-apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cellsIn: International Journal of Oncology Jg. 46 (2015) Nr. 4, S. 1629 - 1636ISSN: 1019-6439Online Volltext: dx.doi.org/ (Open Access)
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Resveratrol induces apoptosis and alters gene expression in human fibrosarcoma cellsIn: Anticancer Research Jg. 35 (2015) Nr. 2, S. 767 - 774ISSN: 0250-7005
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Altering gene expression by aminocoumarins : The role of DNA supercoiling in Staphylococcus aureusIn: BMC Genomics Jg. 15 (2014) Nr. 1, S. 291ISSN: 1471-2164Online Volltext: dx.doi.org/ (Open Access)
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Everolimus Prevents Podocyte Injury Via Stabilizing Tubb2b And Dcdc2 ExpressionIn: Pediatric Nephrology Jg. 29 (2014) Nr. 9, S. 1674 - 1674ISSN: 0931-041XOnline Volltext: dx.doi.org/
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Evolutionary origin and methylation status of human intronic CpG islands that are not present in mouseIn: Genome Biology and Evolution Jg. 6 (2014) Nr. 7, S. 1579 - 1588ISSN: 1759-6653Online Volltext: dx.doi.org/ (Open Access)
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Genome-wirde DNA copy number analysis of choroid plexus tumorsIn: Neuro-Oncology Jg. 16 (2014) Nr. Suppl. 1, S. 134ISSN: 1522-8517; 1523-5866Online Volltext: dx.doi.org/
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High-resolution genomic analysis of choroid plexus tumors separates two genetic entities and identifies recurrent focal alterationsIn: Brain Pathology Jg. 24 (2014) Nr. Suppl. 1, S. 73 - 74ISSN: 1750-3639; 1015-6305Online Volltext: dx.doi.org/
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Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in MiceIn: PLoS ONE Jg. 9 (2014) Nr. 7, S. e103250ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-?B signaling pathwayIn: Acta Neuropathologica Jg. 127 (2014) Nr. 4, S. 609 - 611ISSN: 0001-6322; 1432-0533Online Volltext: dx.doi.org/
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Supratentorial ependymomas of childhood carry C11orf95-rela fusions leading to activation of the NF-KB signalling pathwayIn: Neuro-Oncology Jg. 16 (2014) Nr. Suppl. 1, S. i24ISSN: 1522-8517; 1523-5866Online Volltext: dx.doi.org/
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Supratentorial ependymomas of childhood carry C11orf95–RELA fusions leading to pathological activation of the NF-κB signaling pathwayIn: Acta Neuropathologica Jg. 127 (2014) Nr. 4, S. 609 - 611ISSN: 0001-6322; 1432-0533Online Volltext: dx.doi.org/
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The BRAF-MEK-ERK pathway in hairy cell leukemia : a comprehensive dissection in primary leukemic cells of its biological and therapeutic relevanceIn: Haematologica Jg. 99 (2014) Nr. Suppl. 1, S. 502ISSN: 0390-6078; 1592-8721(Open Access)
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Tumor microenvironment-dependent heterogeneity and cytogenetic abnormality of tumor endothelial cells in human colorectal carcinomaIn: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. e22012ISSN: 0732-183X; 1527-7755Online Volltext: dx.doi.org/
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WISP 1 is an important survival factor in human mesenchymal stromal cellsIn: Gene Jg. 551 (2014) Nr. 2, S. 243 - 254ISSN: 0378-1119Online Volltext: dx.doi.org/
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microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigsIn: Pflügers Archiv: European Journal of Physiology Jg. 466 (2014) Nr. 10, S. 1953 - 1961ISSN: 1432-2013; 0031-6768; 0365-267XOnline Volltext: dx.doi.org/
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A comprehensive molecular study on Coffin–Siris and Nicolaides–Baraitser syndromes identifies abroad molecular and clinical spectrum converging on altered chromatin remodelingremodelingIn: Human Molecular Genetics Jg. 22 (2013) Nr. 25, S. 5121 - 5135ISSN: 1460-2083; 0964-6906Online Volltext: dx.doi.org/
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Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell deathIn: European Journal of Cancer Jg. 49 (2013) Nr. Suppl. 2, S. 101ISSN: 0959-8049Online Volltext: dx.doi.org/
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Clinical and mutation data in 12 patients with the clinical diagnosis of Nager syndromeIn: Human Genetics Jg. 132 (2013) Nr. 8, S. 885 - 898ISSN: 0340-6717; 1432-1203Online Volltext: dx.doi.org/
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Complementation of non-tumorigenicity of HPV18-positive cervical carcinoma cells involves differential mRNA expression of cellular genes including potential tumor suppressor genes on chromosome 11q13In: Cancer Genetics Jg. 206 (2013) Nr. 7-8, S. 279 - 292ISSN: 2210-7762Online Volltext: dx.doi.org/
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Effects of TRAIL and taurolidine on apoptosis and proliferation in human rhabdomyosarcoma, leiomyosarcoma and epithelioid cell sarcomaIn: International Journal of Oncology Jg. 42 (2013) Nr. 3, S. 945 - 956ISSN: 1791-2423Online Volltext: dx.doi.org/ (Open Access)
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Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3In: Nature Genetics Jg. 45 (2013) Nr. 8, S. 933 - 936ISSN: 1061-4036; 1546-1718Online Volltext: dx.doi.org/
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Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1(+) effector memory phenotypeIn: Cancer Immunology, Immunotherapy Jg. 62 (2013) Nr. 11, S. 1697 - 1709ISSN: 0340-7004; 1432-0851Online Volltext: dx.doi.org/
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FTO levels affect RNA modification and the transcriptomeIn: European Journal of Human Genetics Jg. 21 (2013) Nr. 3, S. 317 - 323ISSN: 1018-4813; 1476-5438Online Volltext: dx.doi.org/
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Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 196ISSN: 0378-584X; 1423-0240
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Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic LeukemiaIn: PLoS ONE Jg. 23 (2013) Nr. 8, S. e72107ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivoIn: Cancer Cell Jg. 23 (2013) Nr. 1, S. 77 - 92ISSN: 1535-6108; 1878-3686Online Volltext: dx.doi.org/ (Open Access)
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Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degenerationIn: Aging Cell Jg. 12 (2013) Nr. 6, S. 988 - 999ISSN: 1474-9718; 1474-9726Online Volltext: dx.doi.org/
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Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)In: Blood Jg. 120 (2012) Nr. 21, S. 3512ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
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Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic LeukemiaIn: PLoS ONE Jg. 7 (2012) Nr. 12, S. e34347ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchangeIn: Nucleic Acids Research Jg. 40 (2012) Nr. 1, S. 65 - 74ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access)
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Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cellsIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 50 (2012) Nr. 3, S. 723 - 732ISSN: 1873-2763; 8756-3282Online Volltext: dx.doi.org/
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LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppressionIn: Nature Genetics Jg. 44 (2012) Nr. 11, S. 1199 - 1206ISSN: 1061-4036; 1546-1718Online Volltext: dx.doi.org/
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Progranulin plasma concentration is a novel independent prognostic marker in chronic lymphocytic leukemiaIn: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 100ISSN: 0378-584X; 1423-0240
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Protein Kinase C-beta Dependent Activation of NF-kappa B in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B-Cells in VivoIn: Blood Jg. 120 (2012) Nr. 21, S. 314ISSN: 1528-0020; 0006-4971
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Significance of chromosomal aberrations and HMGA2 expression in Paroxysmal Nocturnal Hemoglobinuria (PNH)In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 220 - 221ISSN: 0378-584X; 1423-0240
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TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in HT1080 human fibrosarcoma cellsIn: Anticancer Research Jg. 32 (2012) Nr. 7, S. 2967 - 2984ISSN: 0250-7005; 1791-7530
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The Transcriptional Profile of Mesenchymal Stem Cell Populations in Primary Osteoporosis Is Distinct and Shows Overexpression of Osteogenic InhibitorsIn: PLoS ONE Jg. 7 (2012) Nr. 9, S. e45142ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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A Systematic Analysis of the 3′UTR of HNF4A mRNA Reveals an Interplay of Regulatory Elements Including miRNA Target SitesIn: PLoS ONE Jg. 6 (2011) Nr. 11, S. 0027438ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletionsIn: European Journal of Human Genetics Jg. 19 (2011) Nr. 9, S. 947 - 958ISSN: 1018-4813Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis : release of pro-inflammatory cytokines and chemokinesIn: Microbes and Infection Jg. 13 (2011) Nr. 11, S. 953 - 962ISSN: 1286-4579; 1769-714XOnline Volltext: dx.doi.org/
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Loss at chromosome arm 16q in retinoblastoma : confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted regionIn: Genes, Chromosomes and Cancer Jg. 50 (2011) Nr. 5, S. 327 - 337ISSN: 1098-2264; 1045-2257Online Volltext: dx.doi.org/
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Miz-1 is required to coordinate the expression of TCRβ and p53 effector genes at the pre-TCR "β-selection" checkpointIn: The Journal of Immunology Jg. 187 (2011) Nr. 6, S. 2982 - 2992ISSN: 1550-6606Online Volltext: dx.doi.org/
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The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemiaIn: Leukemia Jg. 25 (2011) Nr. 4, S. 638 - 647ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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A 439 kb-sized homozygous deletion in 17p13.3 leading to biallelic loss of the ASPA as cause of Canavan disease detected by SNP-array analysis : Letter to the EditorIn: Molecular Genetics and Metabolism Jg. 99 (2010) Nr. 2, S. 184 - 185ISSN: 1096-7206; 1096-7192Online Volltext: dx.doi.org/
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Aging of Xenopus tropicalis Eggs Leads to Deadenylation of a Specific Set of Maternal mRNAs and Loss of Developmental PotentialIn: PLoS ONE Jg. 5 (2010) Nr. 10, S. e13532ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Erratum zu: Identifikation überexprimierter Gene in myxoid-rundzelligen Liposarkomen. DNA-Mikroarray-Analyse und immunhistochemische KorrelationIn: Der Pathologe Jg. 31 (2010) Nr. 3, S. 198ISSN: 0172-8113; 1432-1963Online Volltext: dx.doi.org/
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Functional signature of human islet-derived precursor cells compared to bone marrow-derived mesenchymal stem cellsIn: Stem Cells and Development Jg. 19 (2010) Nr. 5, S. 679 - 691ISSN: 1547-3287; 1557-8534; 1061-6128; 1525-8165Online Volltext: dx.doi.org/
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Gene dosage effects in chronic lymphocytic leukemiaIn: Cancer Genetics and Cytogenetics Jg. 203 (2010) Nr. 2, S. 149 - 160ISSN: 1873-4456; 0165-4608Online Volltext: dx.doi.org/
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Identifikation überexprimierter Gene in myxoid-rundzelligen Liposarkomen : DNA-Mikroarray-Analyse und immunhistochemische KorrelationIn: Der Pathologe Jg. 31 (2010) Nr. 1, S. 60 - 65ISSN: 1432-1963; 0172-8113Online Volltext: dx.doi.org/
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Malignant fibrous histiocytoma-pleomorphic sarcoma, NOS gene expression, histology, and clinical course : A pilot studyIn: Langenbeck's Archives of Surgery Jg. 395 (2010) Nr. 3, S. 261 - 275ISSN: 1435-2451; 1435-2443Online Volltext: dx.doi.org/
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Percentage of smudge cells determined on routine blood smears is a novel prognostic factor in chronic lymphocytic leukemiaIn: Leukemia Research Jg. 34 (2010) Nr. 7, S. 892 - 898ISSN: 1873-5835; 0145-2126Online Volltext: dx.doi.org/
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Synergistic effects of sonoporation and taurolidin/TRAIL on apoptosis in human fibrosarcomaIn: Ultrasound in Medicine and Biology Jg. 36 (2010) Nr. 11, S. 1893 - 1906ISSN: 1879-291X; 0301-5629Online Volltext: dx.doi.org/
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Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60In: Chromosoma Jg. 119 (2010) Nr. 1, S. 99 - 113ISSN: 0009-5915; 1432-0886Online Volltext: dx.doi.org/
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Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemiaIn: European Journal of Haematology Jg. 83 (2009) Nr. 4, S. 320 - 327ISSN: 1600-0609; 0902-4441; 0036-553XOnline Volltext: dx.doi.org/
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Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : implications for therapyIn: Cancer Research Jg. 69 (2009) Nr. 5, S. 2065 - 2071ISSN: 1538-7445; 0008-5472Online Volltext: dx.doi.org/ (Open Access)
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Recurrent loss, but lack of mutations, of the SMARCB1 tumor suppressor gene in T-cell prolymphocytic leukemia with TCL1A–TCRAD juxtapositionIn: Cancer Genetics and Cytogenetics Jg. 192 (2009) Nr. 1, S. 44 - 47ISSN: 1873-4456Online Volltext: dx.doi.org/
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Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cellsIn: Leukemia Research Jg. 32 (2008) Nr. 10, S. 1565 - 1572ISSN: 1873-5835Online Volltext: dx.doi.org/
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Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cellsIn: DNA Repair Jg. 7 (2008) Nr. 10, S. 1757 - 1764ISSN: 1568-7864; 1568-7856Online Volltext: dx.doi.org/
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MYCN regulates oncogenic MicroRNAs in neuroblastomaIn: International Journal of Cancer Jg. 122 (2008) Nr. 3, S. 699 - 704ISSN: 0020-7136; 1097-0215Online Volltext: dx.doi.org/
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Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q11q32)In: Leukemia Jg. 21 (2007) Nr. 10, S. 2153 - 2163ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Neurotrophin receptor status influences the capacity of nonhomologous DNA end joining INSY5Y neuroblastoma cellsIn: Klinische Pädiatrie Jg. 219 (2007) Nr. 3, S. 187 - 187ISSN: 0300-8630; 1439-3824
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Nuclear export is essential for the tumor-promoting activity of survivinIn: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 Jg. 21 (2007) Nr. 1, S. 207 - 216ISSN: 0892-6638; 0892-6638
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The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex proteinIn: Cell Cycle Jg. 6 (2007) Nr. 12, S. 1502 - 1509ISSN: 1538-4101; 1554-8627Online Volltext: dx.doi.org/
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Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression statusIn: Leukemia Jg. 20 (2006) Nr. 10, S. 1774 - 1782ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Lipoprotein lipase expression is a novel prognostic factor in B-cell chronic lymphocytic leukemiaIn: Leukemia & Lymphoma Jg. 47 (2006) Nr. 6, S. 1053 - 1061ISSN: 1029-2403Online Volltext: dx.doi.org/
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MicroRNA expression analysis in neuroblastoma using pligonuclectide arraysIn: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 194ISSN: 0300-8630; 1439-3824
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Microarray analysis defines IPL/TSSC3 as a potential target mediating the synergistic effects of combined thermo-chemotherapy in neuroblastoma cellsIn: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 192 - 193ISSN: 0300-8630; 1439-3824Online Volltext: dx.doi.org/
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Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemiaIn: Leukemia Jg. 19 (2005) Nr. 5, S. 750 - 758ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastomaIn: Oncogene Jg. 24 (2005) Nr. 42, S. 6441 - 6449ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/
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Gene signatures of testicular seminoma with emphasis on expression of ets variant gene 4In: Cellular and Molecular Life Sciences - CMLS Jg. 62 (2005) Nr. 19-20, S. 2359 - 2368ISSN: 1420-682X; 1420-9071Online Volltext: dx.doi.org/
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Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomasIn: Oncogene Jg. 24 (2005) Nr. 1, S. 165 - 177ISSN: 0950-9232; 1476-5594
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Prediction of clinical outcome and biological characterization of neuroblastoma by expression profilingIn: Oncogene Jg. 24 (2005) Nr. 53, S. 7902 - 7912ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/
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Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemiaIn: Blood Jg. 101 (2003) Nr. 7, S. 2748 - 2755ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
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Microarray-analysis : a new approach to study the molecular mechanisms of thermo-chemotherapyIn: Klinische Pädiatrie Jg. 215 (2003) Nr. 6, S. 298 - 302ISSN: 0300-8630; 1439-3824Online Volltext: dx.doi.org/
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ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemiaIn: Leukemia Jg. 17 (2003) Nr. 12, S. 2426 - 2434ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Der Biochip : Neue Horizonte in Prävention, Diagnose und Nachsorge von TumorerkrankungenIn: Essener Unikate: Berichte aus Forschung und Lehre (2001) Nr. 15 : Klinische Onkologie – Fortschritte in der Behandlung von Krebserkrankungen, S. 12 - 19ISSN: 1869-3881Online Volltext (Open Access)
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Anti-leukemic activity through CDK9 inhibition in T-cell prolymphocytic leukemia
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Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia : Results of an in Vitro and In Vivo Analysis
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Acute Myeloid Leukemia Induced Remodelling of the Human Bone Marrow Niche Predicts Clinical Outcome
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CDK9 Inhibition with LDC526 Is an Effective Treatment for T-Cell Prolymphocytic Leukemia (T-PLL) in VitroIn: Blood Jg. 130 (2017) Nr. Suppl. 1, S. 1262ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
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Genomic profiling of T-cell Prolymphocytic Leukemia (T-PLL) identifies novel recurrent mutations in SAMHD1 and PTPRC
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Leipzig, 14.–18. Oktober 2016,In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 238 - 238ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584XOnline Volltext: dx.doi.org/ -
The AP-1 transcription factor BATF3 regulates MYC expression and is required for tumor cell survival in classical Hodgkin lymphoma and anaplastic large cell lymphomaIn: Haematologica Jg. 101 (2016) Nr. S 5: You have access 10th International Symposium on Hodgkin Lymphoma, Cologne, Germany, October 22–25, 2016, Abstract Book, S. 2ISSN: 0390-6078; 1592-8721(Open Access)
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Einzelnukleotid Polymorphismen in Reparaturproteinen sind prognoserelevant für des Überleben von Kopf-Hals- Tumorpatienten nach postoperativer Radiochemotherapie mit Cisplatin (DKTK-ROG)
21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,In: Strahlentherapie und Onkologie Jg. 191 (2015) Nr. Suppl. 1, S. 28 - S. 29ISSN: 0179-7158; 1439-099XOnline Volltext: dx.doi.org/ -
Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell deathIn: European Journal of Cancer Jg. 50 (2014) Nr. Suppl. 5, S. 51ISSN: 0959-8049Online Volltext: dx.doi.org/
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The transcriptome of hMSC from osteoporotic donors is distinct from hMSC of 80+ donors
ECTS 2012, 39th Annual Congress; 19-23 May 2012; Stockholm, Sweden,In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 50 (2012) Nr. Suppl. 1, S. S83ISSN: 1873-2763; 8756-3282Online Volltext: dx.doi.org/ -
Modulation of Proliferation in MCF7 Cells by Regulated Expression of KLF2, 4, 6 and Ki-67 After Treatment With Zoledronic AcidIn: European Journal of Cancer Jg. 47 (2011) Nr. Suppl. 1, S. 359ISSN: 0959-8049Online Volltext: dx.doi.org/
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Progranulin plasma levels predict time to first treatment and overall survival in chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 196 - 196ISSN: 0378-584X; 1423-0240; 2296-5262; 2296-5270Online Volltext: dx.doi.org/ -
Comparing the pharmacological effects of the novel Locked Nucleic Acid (LNA) modified antisense Bcl-2 inhibitor SPC2996 and G3139 (oblimersen) in preclinical models of chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 184ISBN: 978-3-8055-9633-6 ISSN: 0378-584X; 1423-0240; 2296-5262; 2296-5270Online Volltext: dx.doi.org/ -
Cryptochrome 1 (CRY1) promoter methylation is associated with good prognosis in B-cell chronic lymphocytic leukemia (CLL)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 240 - 241ISBN: 978-3-8055-9633-6 ISSN: 0378-584X; 1423-0240; 2296-5270; 2296-5262Online Volltext: dx.doi.org/ -
Expanded CD8(+) T-cells of murine and human B-CLL are driven into a senescent KLRG1(+) effector memory phenotypeIn: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 201ISBN: 978-3-8055-9633-6 ISSN: 0378-584X; 1423-0240; 2296-5262; 2296-5270Online Volltext: dx.doi.org/
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Expanded CLL CD8(+) T-Cells Are Driven Into a Senescent KLRG1(+) Effector Memory PhenotypeIn: Blood Jg. 116 (2010) Nr. 21, S. 403ISSN: 1528-0020; 0006-4971
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Prevalence of B cell lymphoproliferative disorders in patients with chronic hepatitis C (CHC)
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The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 42ISBN: 978-3-8055-9633-6 ISSN: 0378-584X; 1423-0240; 2296-5262; 2296-5270Online Volltext: dx.doi.org/ -
Locus-specific DNA methylation analysis by targeted deep bisulfite sequencingIn: Epigenome Editing: Methods and Protocols 2018, S. 351 - 366ISBN: 978-1-4939-7773-4; 978-1-4939-7774-1Online Volltext: dx.doi.org/