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PD Dr. rer. nat. Ludger Klein-Hitpaß

E-Mail
ludger.klein-hitpass@uni-duisburg-essen.de

Funktionen

  • apl. Professor/in und Privatdozent/in, Institut für Zellbiologie (Tumorforschung)

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Soni, Aashish; Beisser, Daniela; Mladenov, Emil; Höller, Matthias; Wohlers, Inken; Nikolov, Vladimir; Magin, Simon; Mussfeldt, Tamara; Klein-Hitpaß, Ludger; Cornforth, Michael N.; Loucas, Bradford D.; Rahmann, Sven; Iliakis, George
    NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast Cells
    In: Radiation Research , Jg. 203 2025, Nr. 1, S. 37 – 52
    DOI
  • Zec, Kristina; Thiebes, Stephanie; Bottek, Jenny; Siemes, Devon; Spangenberg, Philippa; Trieu, Duc Viet; Kirstein, Nils; Subramaniam, Nirojah; Christ, Robin; Klein, Diana; Jendrossek, Verena; Loose, Maria; Wagenlehner, Florian; Jablonska, Jadwiga; Bracht, Thilo; Sitek, Barbara; Budeus, Bettina; Klein-Hitpaß, Ludger; Theegarten, Dirk; Shevchuk, Olga; Engel, Daniel Robert
    Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection
    In: Frontiers in Immunology , Jg. 14 2023, 1227191
    DOI, Online Volltext (Open Access)
  • Silva de Carvalho, Tayana; Singh, Vikramjeet; Mohamud Yusuf, Ayan; Wang, Jing; Schultz Moreira, Adriana R.; Sanchez-Mendoza, Eduardo H.; Sardari, Maryam; Nascentes Melo, Luiza M.; Döppner, Thorsten R.; Kehrmann, Jan; Scholtysik, Rene; Hitpaß, Ludger; Gunzer, Matthias; Hermann, Dirk M.
    Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing
    In: Brain, Behavior and Immunity , Jg. 100 2022, S. 134 – 144
    DOI (Open Access)
  • Beckmann, Lucia; Obst, Stefanie; Labusek, Nicole; Abberger, Hanna; Köster, Christian; Klein-Hitpaß, Ludger; Schumann, Sven; Kleinschnitz, Christoph; Hermann, Dirk M.; Felderhoff-Müser, Ursula; Bendix, Ivo; Hansen, Wiebke; Herz, Josephine
    Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain Injury
    In: Stroke , Jg. 53 2022, Nr. 2, S. 381 – 390
    DOI (Open Access)
  • Antoni, Anne-Charlotte; Pylaeva, Ekaterina; Budeus, Bettina; Jablonska, Jadwiga; Klein-Hitpaß, Ludger; Dudda, Marcel; Flohé, Stefanie B.
    TLR2-induced CD8⁺ T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsis
    In: Frontiers in Immunology , Jg. 13 2022, 945409
    DOI (Open Access)
  • Lauer, Alexa N.; Scholtysik, Rene; Beineke, Andreas; Baums, Christoph Georg; Klose, Kristin; Valentin-Weigand, Peter; Ishikawa, Hiroshi; Schroten, Horst; Klein-Hitpaß, Ludger; Schwerk, Christian
    A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of Hypoxia
    In: Frontiers in Cellular and Infection Microbiology , Jg. 11 2021, 639620
    DOI (Open Access)
  • Chen, Yiyang; Hoffmeister, Lina Marie; Zaun, Yasmin; Arnold, Lucas; Schmid, Kurt Werner; Giebel, Bernd; Klein-Hitpaß, Ludger; Hanenberg, Helmut; Squire, Anthony; Reinhardt, H. Christian; Dührsen, Ulrich; Bertram, Stefanie; Hanoun, Maher
    Acute myeloid leukemia–induced remodeling of the human bone marrow niche predicts clinical outcome
    In: Blood Advances , Jg. 4 2020, Nr. 20, S. 5257 – 5268
    DOI (Open Access)
  • Johansson, Patricia; Dierichs, Laura; Klein-Hitpaß, Ludger; Bergmann, Anke K.; Möllmann, Michael; Menninger, Sascha; Habenberger, Peter; Klebl, Bert; Siveke, Jens; Dührsen, Ulrich; Choidas, Axel; Dürig, Jan
    Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia
    In: Therapeutic Advances in Hematology , Jg. 11 2020, S. 1 – 15
    DOI, Online Volltext (Open Access)
  • Kehrmann, Jan; Effenberg, Laura; Wilk, Camilla; Schoemer, Davina; Ngo Thi Phuong, Nhi; Adamczyk, Alexandra; Pastille, Eva; Scholtysik, René; Klein-Hitpaß, Ludger; Klopfleisch, Robert; Westendorf, Astrid; Buer, Jan
    Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome
    In: Immunology , Jg. 159 2020, Nr. 3, S. 344 – 353
    DOI (Open Access)
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Budeus, Bettina; Kuhn, Matthias; Lauber, Chris; Seifert, Michael; Roeder, Ingo; Pförtner, Roman; Stuschke, Martin; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencing
    In: Cancers , Jg. 12 2020, Nr. 4, 986
    DOI, Online Volltext (Open Access)
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Röth, Alexander; Möllmann, Michael; Reinhardt, Hans Christian; Dührsen, Ulrich; Dürig, Jan
    Mutations in PIGA cause a CD52-/GPI-anchor-deficient phenotype complicating alemtuzumab treatment in T-cell prolymphocytic leukemia
    In: European Journal of Haematology , Jg. 105 2020, Nr. 6, S. 786 – 796
    DOI (Open Access)
  • Moser, Dirk Alexander; Müller, Sabine; Hummel, Elisabeth M.; Limberg, Anke S.; Dieckmann, Linda; Frach, Leonard; Pakusch, Johanna; Flasbeck, Vera; Brüne, Martin; Beygo, Jasmin; Klein-Hitpaß, Ludger; Kumsta, Robert
    Targeted bisulfite sequencing : A novel tool for the assessment of DNA methylation with high sensitivity and increased coverage
    In: Psychoneuroendocrinology , Jg. 120 2020, 104784
    DOI (Open Access)
  • Kalmbach, Alexander; Schröder, Christopher; Klein-Hitpaß, Ludger; Nordström, Karl; Ulz, Peter; Heitzer, Ellen; Speicher, Michael R.; Rahmann, Sven; Wieczorek, Dagmar; Horsthemke, Bernhard; Bramswig, Nuria C.
    Genome-wide analysis of the nucleosome landscape in individuals with coffin-siris syndrome
    In: Cytogenetics and Cell Genetics , Jg. 159 2019, S. 1 – 11
    DOI (Open Access)
  • Kehrmann, Jan; Menzel, Jannis; Saeedghalati, Mohammadkarim; Obeid, Rima; Schulze, Christina; Holzendorf, Volker; Farahpour, Farnoush; Reinsch, Nico; Klein-Hitpaß, Ludger; Streeck, Hendrik; Hoffmann, Daniel; Buer, Jan; Esser, Stefan
    Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart Disease
    In: The Journal of Infectious Diseases (JID) , Jg. 219 2019, Nr. 3, S. 497 – 508
    DOI (Open Access)
  • Jünger, Stephanie T.; Mynarek, Martin; Wohlers, Inken; Dörner, Evelyn; Mühlen, Anja Zur; Velez-Char, Natalia; Von Hoff, Katja; Rutkowski, Stefan; Warmuth-Metz, Monika; Kortmann, Rolf-Dieter; Timmermann, Beate; Rahmann, Sven; Klein-Hitpaß, Ludger; Von Bueren, Andre O.; Pietsch, Torsten
    Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohort
    In: Acta Neuropathologica Communications , Jg. 7 2019, Nr. 1, 181
    DOI (Open Access)
  • Lollies, Anna; Hartmann, Sylvia; Schneider, Markus; Bracht, Thilo; Weiß, A.L.; Arnolds, Judith; Klein-Hitpaß, Ludger; Sitek, Barbara; Hansmann, Martin Leo; Küppers, Ralf; Weniger, Marc
    An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphoma
    In: Leukemia , Jg. 32 2018, Nr. 1, S. 92 – 101
    DOI
  • Tucci, Felicia A.; Kitanovski, Simo; Johansson, Patricia; Klein-Hitpaß, Ludger; Kahraman, Alisan; Dürig, Jan; Hoffmann, Daniel; Küppers, Ralf
    Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individuals
    In: Blood , Jg. 131 2018, Nr. 5, S. 546 – 557
    DOI (Open Access)
  • Mangolini, Maurizio; Götte, Frederik; Moore, Andrew; Ammon, Tim; Oelsner, Madlen; Lutzny-Geier, Gloria; Klein-Hitpaß, Ludger; Williamson, James C.; Lehner, Paul J.; Dürig, Jan; Möllmann, Michael; Rásó-Barnett, Lívia; Hughes, Katherine; Santoro, Antonella; Méndez-Ferrer, Simón; Oostendorp, Robert A. J.; Zimber-Strobl, Ursula; Peschel, Christian; Hodson, Daniel J.; Schmidt-Supprian, Marc; Ringshausen, Ingo
    Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia
    In: Nature Communications , Jg. 9 2018, 3839
    DOI (Open Access)
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Choidas, Axel; Habenberger, Peter; Mahboubi, Bijan; Kim, Baek; Bergmann, Anke; Scholtysik, René; Brauser, Martina; Lollies, Anna; Siebert, Reiner; Zenz, Thorsten; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia
    In: Blood Cancer Journal , Jg. 8 2018, Nr. 1, 11
    DOI (Open Access)
  • Hendgen-Cotta, Ulrike B.; Esfeld, Sonja; Coman, Cristina; Ahrends, Robert; Klein-Hitpaß, Ludger; Flögel, Ulrich; Rassaf, Tienush; Totzeck, Matthias
    A novel physiological role for cardiac myoglobin in lipid metabolism
    In: Scientific Reports , Jg. 7 2017, S. 43219
    DOI (Open Access)
  • Sucker, Antje; Zhao, Fang; Pieper, Natalia; Heeke, Christina; Maltaner, Raffaela; Stadtler, Nadine; Real, Birgit; Bielefeld, Nicola; Howe, Sebastian; Weide, Benjamin; Gutzmer, Ralf; Utikal, Jochen; Loquai, Carmen; Gogas, Helen; Klein-Hitpaß, Ludger; Zeschnigk, Michael; Westendorf, Astrid; Trilling, Mirko; Horn, Susanne; Schilling, Bastian; Schadendorf, Dirk; Griewank, Klaus; Paschen, Annette
    Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesions
    In: Nature Communications , Jg. 8 2017, 15440
    DOI (Open Access)
  • Wöchtl, Bettina; Gunzer, Florian; Gerner, Wilhelm; Gasse, Hagen; Koch, Michaela; Bagó, Zoltán; Ganter, Martin; Weissenböck, Herbert; Dinhopl, Nora; Coldewey, Sina M.; Von Altrock, Alexandra; Waldmann, Karl-Heinz; Saalmüller, Armin; Zimmermann, Kurt; Steinmann, Jörg; Kehrmann, Jan; Klein-Hitpaß, Ludger; Blom, Jochen; Ehricht, Ralf; Engelmann, Ines; Hennig-Pauka, Isabel
    Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7
    In: Gut Pathogens , Jg. 9 2017, S. 30
    DOI (Open Access)
  • Pohl, Judith-Mira; Gutweiler, Sebastian; Thiebes, Stephanie; Volke, Julia K.; Klein-Hitpaß, Ludger; Zwanziger, Denise; Gunzer, Matthias; Jung, Steffen; Agace, William W.; Kurts, Christian; Engel, Daniel Robert
    Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus
    In: Gut , Jg. 66 2017, Nr. 12, S. 2110 – 2120
    DOI (Open Access)
  • Mangolini, M.; Gotte, F.; Ammon, T.; Oelsner, M.; Klein-Hitpaß, Ludger; Dürig, Jan; Hughes, K.; Lutzny, G.; Strobl, U.; Ringshausen, I.
    NOTCH-signaling in the tumor microenvironment is required for canonical WNT signaling in CLL cells
    In: Leukemia and Lymphoma , Jg. 58 2017, Nr. Suppl. 1, XVII International Workshop on Chronic Lymphocytic Leukemia 2017 May 12--15, 2017, New York, S. 125 – 126
    DOI
  • Hönes, Georg Sebastian; Rakov, Helena; Logan, John; Liao, Xiao-Hui; Werbenko, Eugenie; Pollard, Andrea S.; Praestholm, Stine M.; Siersbaek, Majken S.; Rijntjes, Eddy; Gassen, Janina; Latteyer, Soren; Engels, Kathrin; Strucksberg, Karl-Heinz; Kleinbongard, Petra; Zwanziger, Denise; Rozman, Jan; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Klein-Hitpaß, Ludger; Köhrle, Josef; Armstrong, David L.; Grontved, Lars; Bassett, J. H. Duncan; Williams, Graham R.; Refetoff, Samuel; Führer, Dagmar; Möller, Lars
    Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 114 2017, Nr. 52, S. E11323 – E11332
    DOI
  • Japp, Anna Sophia; Klein-Hitpaß, Ludger; Denkhaus, Dorota; Pietsch, Torsten
    OTX2 defines a subgroup of atypical teratoid rhabdoid tumors with close relationship to choroid plexus tumors
    In: Journal of Neuropathology & Experimental Neurology (JNEN) , Jg. 76 2017, Nr. 1, S. 32 – 38
    DOI (Open Access)
  • Schröder, Christopher; Leitão, Elsa; Wallner, Stefan; Schmitz, Gerd; Klein-Hitpaß, Ludger; Sinha, Anupam; Jöckel, Karl-Heinz; Heilmann-Heimbach, Stefanie; Hoffmann, Per; Nöthen, Markus M.; Steffens, Michael; Ebert, Peter; Rahmann, Sven; Horsthemke, Bernhard
    Regions of common inter-individual DNA methylation differences in human monocytes: Genetic basis and potential function
    In: Epigenetics and Chromatin , Jg. 10 2017, Nr. 1, S. 37
    DOI (Open Access)
  • Kehrmann, Jan; Veckollari, B.; Schmidt, Dirk; Schildgen, Oliver; Schildgen, Verena; Wagner, N.; Zeschnigk, Michael; Klein-Hitpaß, Ludger; Witzke, Oliver; Buer, Jan; Steinmann, Jörg
    The lung microbiome in patients with pneumocystosis
    In: BMC Pulmonary Medicine , Jg. 17 2017, Nr. 1, S. 170
    DOI (Open Access)
  • Latteyer, Sören; Möller, Lars; Führer, Dagmar; Schmid, Kurt Werner; Pöppel, Thorsten; Khandanpour, Cyrus; Klein-Hitpaß, Ludger; Zwanziger, Denise
    A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A
    In: The Journal of Clinical Endocrinology & Metabolism (JCEM) , Jg. 101 2016, Nr. 3, S. 1016 – 1022
    DOI (Open Access)
  • Fielitz, Kathrin; Althoff, Kristina; De Preter, Katleen; Nonnekens, Julie; Ohli, Jasmin; Elges, Sandra; Hartmann, Wolfgang; Klöppel, Günter; Knösel, Thomas; Schulte, Marc; Klein-Hitpaß, Ludger; Beisser, Daniela; Reis, Henning; Eyking, Annette; Cario, Elke; Schulte, Johannes; Schramm, Alexander; Schüller, Ulrich
    Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells
    In: OncoTarget , Jg. 7 2016, Nr. 46, S. 74415 – 74426
    DOI (Open Access)
  • Wallner, Stefan; Schröder, Christopher; Leitão, Elsa; Berulava, Tea; Haak, Claudia; Beisser, Daniela; Rahmann, Sven; Richter, Andreas S.; Manke, Thomas; Bönisch, Ulrike; Arrigoni, Laura; Fröhler, Sebastian; Klironomos, Filippos; Chen, Wei; Rajewsky, Nikolaus; Müller, Fabian; Ebert, Peter; Lengauer, Thomas; Barann, Matthias; Rosenstiel, Philip; Gasparoni, Gilles; Nordström, Karl; Walter, Jörn; Brors, Benedikt; Zipprich, Gideon; Felder, Bärbel; Klein-Hitpaß, Ludger; Attenberger, Corinna; Schmitz, Gerd; Horsthemke, Bernhard
    Epigenetic dynamics of monocyte-to-macrophage differentiation
    In: Epigenetics and Chromatin , Jg. 9 2016, S. 33
    DOI (Open Access)
  • Hönes, J M; Botezatu, L; Helness, A; Vadnais, C; Vassen, L; Robert, F; Hergenhan, S M; Thivakaran, A; Schütte, J; Al-Matary, Y S; Lams, R F; Fraszscak, J; Makishima, H; Radivoyevitch, T; Przychodzen, B; da Conceição Castro, S V; Görgens, A; Giebel, Bernd; Klein-Hitpaß, Ludger; Lennartz, K; Heuser, M; Thiede, C; Ehninger, G; Dührsen, Ulrich; Maciejewski, J; Möröy, T; Khandanpour, Cyrus
    GFI1 as a novel prognostic and therapeutic factor for AML/MDS
    In: Leukemia , Jg. 30 2016, Nr. 6, S. 1237 – 1245
    DOI
  • Naschberger, Elisabeth; Liebl, Andrea; Schellerer, Vera S; Schütz, Manuela; Britzen-Laurent, Nathalie; Kölbel, Patrick; Schaal, Ute; Haep, Lisa; Regensburger, Daniela; Wittmann, Thomas; Klein-Hitpaß, Ludger; Rau, Tilman T; Dietel, Barbara; Méniel, Valérie S; Clarke, Alan R; Merkel, Susanne; Croner, Roland S; Hohenberger, Werner; Stürzl, Michael
    Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma
    In: The Journal of Clinical Investigation (JCI) , Jg. 126 2016, Nr. 11, S. 4187 – 4204
    DOI
  • Johansson, Patricia; Bergmann, Anke; Rahmann, Sven; Wohlers, Inken; Scholtysik, René; Przekopowitz, Martina; Seifert, Marc; Tschurtschenthaler, Gertraud; Webersinke, Gerald; Jäger, Ulrich; Siebert, Reiner; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan; Küppers, Ralf
    Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia
    In: International Journal of Cancer , Jg. 138 2016, Nr. 1, S. 121 – 124
    DOI (Open Access)
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Grabellus, Florian; Arnold, Georg; Klapper, Wolfram; Pförtner, Roman; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas
    In: OncoTarget , Jg. 7 2016, Nr. 38, S. 62627 – 62639
    DOI (Open Access)
  • Sellmann, Ludger; Scholtysik, Rene; de Beer, Dirk; Eisele, Lewin; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Düring, Jan; Röth, Alexander; Baerlocher, Gabriele
    Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia
    In: Leukemia and Lymphoma , Jg. 57 2016, Nr. 3, S. 590 – 595
    DOI
  • Althoff, K; Beckers, A; Bell, E; Nortmeyer, M; Thor, T; Sprüssel, A; Lindner, S; De Preter, K; Florin, A; Heukamp, L C; Klein-Hitpaß, Ludger; Astrahantseff, K; Kumps, C; Speleman, F; Eggert, A; Westermann, F; Schramm, Alexander; Schulte, Johannes
    A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
    In: Oncogene , Jg. 34 2015, Nr. 26, S. 3357 – 3368
    DOI (Open Access)
  • Lindner, Sven; Bachmann, Hagen Sjard; Odersky, Andrea; Schaefers, Simon; Klein-Hitpaß, Ludger; Hero, Barbara; Fischer, Matthias; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma
    In: Biomedical Reports , Jg. 3 2015, Nr. 4, S. 443 – 446
    DOI
  • Pettirossi, Valentina; Santi, Alessia; Imperi, Elisa; Russo, Guido; Pucciarini, Alessandra; Bigerna, Barbara; Schiavoni, Gianluca; Fortini, Elisabetta; Spanhol-Rosseto, Ariele; Sportoletti, Paolo; Mannucci, Roberta; Martelli, Maria P.; Klein-Hitpaß, Ludger; Falini, Brunangelo; Tiacci, Enrico
    BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity
    In: Blood , Jg. 125 2015, Nr. 8, S. 1207 – 1216
    DOI (Open Access)
  • Steinert, Andre F.; Kunz, Manuela; Prager, Patrick; Göbel, Sascha; Klein-Hitpaß, Ludger; Ebert, Regina; Nöth, Ulrich; Jakob, Franz; Gohlke, Frank
    Characterization of bursa subacromialis-derived mesenchymal stem cells
    In: Stem Cell Research & Therapy , Jg. 6 2015, S. 114
    DOI (Open Access)
  • Britzen-Laurent, Nathalie; Naschberger, Elisabeth; Rau, Tilman T.; Dietel, Barbara; Klein-Hitpaß, Ludger; Stürzl, Michael; Liebl, Andrea; Grenz, Sandra; Hohenberger, Werner; Schaal, Ute; Merkel, Susanne; Schellerer, Vera S.; Croner, Roland S.; Kölbel, Patrick
    Endothelial cells isolated from colorectal carcinoma exhibit tumor microenvironment-dependent plasticity allowing the identification of SPARCL1 as a novel endothelial cell quiescence factor
    In: Cancer Research , Jg. 75 2015, Nr. 15 Suppl., S. 2375
    DOI
  • Jeruschke, Stefanie; Jeruschke, Kay; DiStasio, Andrew; Karaterzi, Sinem; Büscher (A.), Anja; Nalbant, Perihan; Klein-Hitpaß, Ludger; Hoyer, Peter Friedrich; Weiss, Jürgen; Stottmann, Rolf W; Weber, Stefanie
    Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression
    In: PLoS ONE , Jg. 10 2015, Nr. 9, S. e0137043
    DOI (Open Access)
  • Li, Yu; Dürig, Jan; Göbel, Maria; Hanoun, Maher; Klein-Hitpaß, Ludger; Dührsen, Ulrich
    Functional abnormalities and changes in gene expression in fibroblasts and macrophages from the bone marrow of patients with acute myeloid leukemia
    In: International Journal of Hematology , Jg. 102 2015, Nr. 3, S. 278 – 288
    DOI
  • Japp, Anna Sophia; Gessi, Marco; Messing-Jünger, Martina A.; Denkhaus, Dorata; Zur Mühlen, Anja; Wolff, Johannes Ernst; Hartung, Stefan; Kordes, Uwe; Klein-Hitpaß, Ludger; Pietsch, Thorsten
    High-Resolution Genomic Analysis Does Not Qualify Atypical Plexus Papilloma as a Separate Entity Among Choroid Plexus Tumors
    In: Journal of Neuropathology & Experimental Neurology (JNEN) , Jg. 74 2015, Nr. 2, S. 110 – 120
    DOI (Open Access)
  • Büchel, Janine; Bartosova, Maria; Eich, Gwendolyn; Wittenberger, Timo; Klein-Hitpaß, Ludger; Steppan, Sonja; Hackert, Thilo; Schaefer, Franz; Passlick-Deetjen, Jutta; Schmitt, Claus P.
    Interference of peritoneal dialysis fluids with cell cycle mechanisms
    In: Peritoneal Dialysis International , Jg. 35 2015, Nr. 3, S. 259 – 274
    DOI (Open Access)
  • Berulava, Tea; Rahmann, Sven; Rademacher, Katrin; Klein-Hitpaß, Ludger; Horsthemke, Bernhard
    N6-Adenosine Methylation in MiRNAs
    In: PLoS ONE , Jg. 10 2015, Nr. 2, S. e0118438
    DOI (Open Access)
  • Graser, Stephanie; Mentrup, Birgit; Schneider, Doris; Klein-Hitpaß, Ludger; Jakob, Franz; Hofmann, Christine
    Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line
    In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) , Jg. 79 2015, S. 150 – 161
    DOI
  • Harati, Kamran; Slodnik, Pawel; Chromik, Ansgar M.; Behr, Björn; Goertz, Ole; Hirsch, Tobias; Kapalschinski, Nicolai; Klein-Hitpaß, Ludger; Kolbenschlag, Jonas; Uhl, Waldemar; Lehnhardt, Marcus; Daigeler, Adrien
    Pro-apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cells
    In: International Journal of Oncology , Jg. 46 2015, Nr. 4, S. 1629 – 1636
    DOI (Open Access)
  • Harati, Kamran; Slodnik, Pawel; Chromik, Ansgar Michael; Goertz, Ole; Hirsch, Tobias; Kapalschinski, Nikolai; Klein-Hitpaß, Ludger; Kolbenschlag, Jonas; Uhl, Waldemar; Lehnhardt, Marcus; Daigeler, Adrien
    Resveratrol induces apoptosis and alters gene expression in human fibrosarcoma cells
    In: Anticancer Research , Jg. 35 2015, Nr. 2, S. 767 – 774
  • Schröder, Wiebke; Bernhardt, Jörg; Marincola, Gabriella; Klein-Hitpaß, Ludger; Herbig, Alexander; Krupp, Guido; Nieselt, Kay; Wolz, Christiane
    Altering gene expression by aminocoumarins : The role of DNA supercoiling in Staphylococcus aureus
    In: BMC Genomics , Jg. 15 2014, Nr. 1, S. 291
    DOI (Open Access)
  • Jeruschke, Stefanie; Rekasi, Heike; Karaterzi, Sinem; Buescher, AnjaKarin; Klein-Hitpaß, Ludger; Jeruschke, Kay; Weiss, Juergen; Saleem, MoinAhson; Hoyer, Peter Friedrich; Nalbant, Perihan; Weber, Stefanie
    Everolimus Prevents Podocyte Injury Via Stabilizing Tubb2b And Dcdc2 Expression
    In: Pediatric Nephrology , Jg. 29 2014, Nr. 9, S. 1674 – 1674
    DOI
  • Rademacher, Katrin; Schröder, Christopher; Kanber, Deniz; Klein-Hitpaß, Ludger; Wallner, Stefan; Zeschnigk, Michael; Horsthemke, Bernhard
    Evolutionary origin and methylation status of human intronic CpG islands that are not present in mouse
    In: Genome Biology and Evolution , Jg. 6 2014, Nr. 7, S. 1579 – 1588
    DOI (Open Access)
  • Japp, Anna; Gessi, Marco; zur Muehlen, Anja; Klein-Hitpaß, Ludger
    Genome-wirde DNA copy number analysis of choroid plexus tumors
    In: Neuro-Oncology , Jg. 16 2014, Nr. Suppl. 1, S. 134
    DOI
  • Japp, A. S.; Gessi, M.; Denkhaus, D.; zur Muehlen, A.; Pietsch, T.; Hartung, S.; Kordes, U.; Messing-Juenger, M.; Wolff, J. E.; Klein-Hitpaß, Ludger
    High-resolution genomic analysis of choroid plexus tumors separates two genetic entities and identifies recurrent focal alterations
    In: Brain Pathology , Jg. 24 2014, Nr. Suppl. 1, S. 73 – 74
    DOI
  • Liedert, Astrid; Röntgen, Viktoria; Schinke, Thorsten; Benisch, Peggy; Ebert, Regina; Jakob, Franz; Klein-Hitpaß, Ludger; Lennerz, Jochen K.; Amling, Michael; Ignatius, Anita
    Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in Mice
    In: PLoS ONE , Jg. 9 2014, Nr. 7, S. e103250
    DOI (Open Access)
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Dörner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-?B signaling pathway
    In: Acta Neuropathologica , Jg. 127 2014, Nr. 4, S. 609 – 611
    DOI
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Doerner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95-rela fusions leading to activation of the NF-KB signalling pathway
    In: Neuro-Oncology , Jg. 16 2014, Nr. Suppl. 1, S. i24
    DOI
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Dörner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95–RELA fusions leading to pathological activation of the NF-κB signaling pathway
    In: Acta Neuropathologica , Jg. 127 2014, Nr. 4, S. 609 – 611
    DOI
  • Santi, A.; Pettirossi, V.; Imperi, E.; Russo, G.; Pucciarini, A.; Bigerna, B.; Fortini, E.; Mannucci, R.; Schiavoni, G.; Nicoletti, I.; Martelli, M. P.; Klein-Hitpaß, Ludger; Falini, B.; Tiacci, E.
    The BRAF-MEK-ERK pathway in hairy cell leukemia : a comprehensive dissection in primary leukemic cells of its biological and therapeutic relevance
    In: Haematologica / The Hematology Journal , Jg. 99 2014, Nr. Suppl. 1, S. 502
    (Open Access)
  • Naschberger, Elisabeth; Schellerer, VeraS; Schaal, Ute; Grenz, Sandra; Liebl, Andrea; Jenzer, Maximilian; Britzen-Laurent, Nathalie; Ekici, ArifB; Klein-Hitpaß, Ludger; Keck, Bastian; Wach, Sven; Rau, TilmanT; Merkel, Susanne; Croner, RolandS; Hohenberger, Werner; Stuerzi, Michael
    Tumor microenvironment-dependent heterogeneity and cytogenetic abnormality of tumor endothelial cells in human colorectal carcinoma
    In: Journal of Clinical Oncology (JCO) , Jg. 32 2014, Nr. 15 Suppl., S. e22012
    DOI
  • Schlegelmilch, Katrin; Keller, Alexander; Zehe, Viola; Hondke, Sylvia; Schilling, Tatjana; Jakob, Franz; Klein-Hitpaß, Ludger; Schütze, Norbert
    WISP 1 is an important survival factor in human mesenchymal stromal cells
    In: Gene , Jg. 551 2014, Nr. 2, S. 243 – 254
    DOI
  • Baars, Theodor; Skyschally, Andreas; Klein-Hitpaß, Ludger; Cario, Elke; Erbel, Raimund; Heusch, Gerd; Kleinbongard, Petra
    microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigs
    In: Pflügers Archiv: European Journal of Physiology , Jg. 466 2014, Nr. 10, S. 1953 – 1961
    DOI
  • Wieczorek, Dagmar; Bögershausen, Nina; Beleggia, Filippo; Steiner-Haldenstätt, Sabine; Pohl, Esther; Li, Yun; Milz, Esther; Martin, Marcel; Thiele, Holger; Altmüller, Janine; Alanay, Yasemin; Kayserili, Hülya; Klein-Hitpaß, Ludger; Böhringer, Stefan; Wollstein, Andreas; Albrecht, Beate; Boduroglu, Koray; Caliebe, Almuth; Chrzanowska, Krystyna; Cogulu, Ozgur; Cristofoli, Francesca; Czeschik, Johanna Christina; Devriendt, Koenraad; Dotti, Maria Teresa; Elcioglu, Nursel; Gener, Blanca; Goecke, Timm O.; Krajewska-Walasek, Małgorzata; Guillén-Navarro, Encarnación; Hayek, Joussef; Houge, Gunnar; Kilic, Esra; Simsek-Kiper, Pelin Özlem; López-González, Vanesa; Küchler, Alma; Lyonnet, Stanislas; Mari, Francesca; Marozza, Annabella; Dramard, Michèle Mathieu; Mikat, Barbara; Morin, Gilles; Morice-Picard, Fanny; Özkinay, Ferda; Rauch, Anita; Renieri, Alessandra; Tinschert, Sigrid; Eda Utine, G.; Vilain, Catheline; Vivarelli, Rossella; Zweier, Christiane; Nürnberg, Peter; Rahmann, Sven; Vermeesch, Joris; Lüdecke, Hermann-Josef; Zeschnigk, Michael; Wollnik, Bernd
    A comprehensive molecular study on Coffin–Siris and Nicolaides–Baraitser syndromes identifies abroad molecular and clinical spectrum converging on altered chromatin remodelingremodeling
    In: Human Molecular Genetics , Jg. 22 2013, Nr. 25, S. 5121 – 5135
    DOI
  • Matschke, Johann; Riffkin, H.; Handrick, R.; Klein-Hitpaß, Ludger; Jendrossek, Verena
    Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell death
    In: European Journal of Cancer (EJC) , Jg. 49 2013, Nr. Suppl. 2, S. 101
    DOI
  • Czeschik, Christina; Voigt, C.; Alanay, Y.; Albrecht, Beate; Avci, S.; Fitzpatrick, D.; Goudie, D.R.; Hehr, U.; Hoogeboom, A.J.; Kayserili, H.; Simsek-Kiper, P.O.; Klein-Hitpaß, Ludger; Küchler, Alma; López-González, V.; Martin, M.; Rahmann, Sven; Schweiger, Bernd; Splitt, M.; Wollnik, B.; Lüdecke, Hermann-Josef; Zeschnigk, Michael; Wieczorek, Dagmar
    Clinical and mutation data in 12 patients with the clinical diagnosis of Nager syndrome
    In: Human Genetics , Jg. 132 2013, Nr. 8, S. 885 – 898
    DOI
  • Kehrmann, Angela; Truong, Ha; Repenning, Antje; Boger, Regina; Klein-Hitpaß, Ludger; Pascheberg, Ulrich; Beckmann, Alf; Opalka, Bertram; Kleine-Lowinski, Kerstin
    Complementation of non-tumorigenicity of HPV18-positive cervical carcinoma cells involves differential mRNA expression of cellular genes including potential tumor suppressor genes on chromosome 11q13
    In: Cancer Genetics , Jg. 206 2013, Nr. 7-8, S. 279 – 292
    DOI
  • Karlisch, Carmen; Harati, Kamran; Chromik, Ansgar Michael; Bulut, Daniel; Klein-Hitpaß, Ludger; Goertz, Ole; Hirsch, Tobias; Lehnhardt, Marcus; Uhl, Waldemar H.; Daigeler, Adrien
    Effects of TRAIL and taurolidine on apoptosis and proliferation in human rhabdomyosarcoma, leiomyosarcoma and epithelioid cell sarcoma
    In: International Journal of Oncology , Jg. 42 2013, Nr. 3, S. 945 – 956
    DOI (Open Access)
  • Martin, Marcel; Maßhöfer, Lars; Temming, Petra; Rahmann, Sven; Metz, Claudia; Bornfeld, Norbert; van de Nes, Johannes; Klein-Hitpaß, Ludger; Hinnebusch, Alan G.; Horsthemke, Bernhard; Lohmann, Dietmar; Zeschnigk, Michael
    Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
    In: Nature Genetics , Jg. 45 2013, Nr. 8, S. 933 – 936
    DOI
  • Goethert, JoachimRud; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Zesewitz, Marie-Loui; Sellmann, Ludger; Röth, Alexander; Pircher, Hanspeter; Dührsen, Ulrich; Dürig, Jan
    Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1(+) effector memory phenotype
    In: Cancer Immunology, Immunotherapy , Jg. 62 2013, Nr. 11, S. 1697 – 1709
    DOI
  • Berulava, Tea; Ziehe, Matthias; Klein-Hitpaß, Ludger; Mladenov, Emil; Thomale, Jürgen; Rüther, Ulrich; Horsthemke, Bernhard
    FTO levels affect RNA modification and the transcriptome
    In: European Journal of Human Genetics , Jg. 21 2013, Nr. 3, S. 317 – 323
    DOI
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, R.; Seifert, Marc; Jäger, Ursula; Tschurtschenthaler, G.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Onkologie , Jg. 36 2013, Nr. Suppl. 7, S. 196
  • Göbel, Maria; Eisele, Lewin; Möllmann, Michael; Hüttmann, Andreas; Johansson, Patricia; Scholtysik, Rene; Bergmann, Manuela; Busch, Raymonde; Döhner, Hartmut; Hallek, Michael; Seiler, Till; Stilgenbauer, Stephan; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan
    Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic Leukemia
    In: PLoS ONE , Jg. 23 2013, Nr. 8, S. e72107
    DOI (Open Access)
  • Lutzny, Gloria; Kocher, Thomas; Schmidt-Supprian, Marc; Rudelius, Martina; Klein-Hitpaß, Ludger; Finch, Andrew J; Dürig, Jan; Wagner, Michaela; Haferlach, Claudia; Kohlmann, Alexander; Schnittger, Susanne; Seifert, Marc; Wanninger, Stefan; Zaborsky, Nadja; Oostendorp, Robert; Ruland, Jürgen; Leitges, Michael; Kuhnt, Toni; Schäfer, Yvonne; Lampl, Benedikt; Peschel, Christian; Egle, Alexander; Ringshausen, Ingo
    Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo
    In: Cancer Cell , Jg. 23 2013, Nr. 1, S. 77 – 92
    DOI (Open Access)
  • Kohler, Julia; Popov, Cvetan; Klotz, Barbara; Alberton, Paolo; Prall, Wolf Christian; Haasters, Florian; Müller-Deubert, Sigrid; Ebert, Regina; Klein-Hitpaß, Ludger; Jakob, Franz; Schieker, Matthias; Docheva, Denitsa
    Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration
    In: Aging Cell , Jg. 12 2013, Nr. 6, S. 988 – 999
    DOI
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, René; Seifert, Marc; Jäger, Ulrich; Tschurtschenthaler, Gertraud; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Blood , Jg. 120 2012, Nr. 21, S. 3512
    DOI
  • Hanoun, Maher; Eisele, Lewin; Suzuki, Masako; Greally, John M.; Hüttmann, Andreas; Aydin, Semra; Scholtysik, René; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan
    Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic Leukemia
    In: PLoS ONE , Jg. 7 2012, Nr. 12, S. e34347
    DOI (Open Access)
  • Heise, Franziska; Chung, Ho-Ryun; Weber, Jan; Xu, Zhenyu; Klein-Hitpaß, Ludger; Steinmetz, Lars M.; Vingron, Martin; Ehrenhofer-Murray, Ann
    Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange
    In: Nucleic Acids Research , Jg. 40 2012, Nr. 1, S. 65 – 74
    DOI (Open Access)
  • Ebert, Regina; Zeck, Sabine; Meissner-Weigl, Jutta; Klotz, Barbara; Rachner, Tilman D.; Benad, Peggy; Klein-Hitpaß, Ludger; Rudert, Maximilian; Hofbauer, Lorenz C.; Jakob, Franz
    Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells
    In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) , Jg. 50 2012, Nr. 3, S. 723 – 732
    DOI
  • Molenaar, Jan J.; Domingo-Fernández, Raquel; Ebus, Marli E.; Lindner, Sven; Koster, Jan; Drabek, Ksenija; Mestdagh, Pieter; Van Sluis, Peter; Valentijn, Linda J.; Van Nes, Johan; Broekmans, Marloes; Haneveld, Franciska; Volckmann, Richard; Bray, Isabella; Heukamp, Lukas; Sprüssel, Annika; Thor, Theresa; Kieckbusch, Kristina; Klein-Hitpaß, Ludger; Fischer, Matthias; Vandesompele, Jo; Schramm, Alexander; Van Noesel, Max M.; Varesio, Luigi; Speleman, Frank; Eggert, Angelika; Stallings, Raymond L.; Caron, Huib N.; Versteeg, Rogier; Schulte, Johannes
    LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
    In: Nature Genetics , Jg. 44 2012, Nr. 11, S. 1199 – 1206
    DOI
  • Gobel, M.; Eisele, Lewin; Hüttmann, Andreas; Bergmann, M.; Busch, R.; Stilgenbauer, S.; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan
    Progranulin plasma concentration is a novel independent prognostic marker in chronic lymphocytic leukemia
    In: Onkologie , Jg. 35 2012, Nr. Suppl. 6, S. 100
  • Lutzny, G.; Kocher, T.; Rudelius, M.; Schmidt-Supprian, M.; Klein-Hitpaß, Ludger; Dürig, Jan; Oostendorp, RAJ; Peschel, C.; Egle, A.; Ringshausen, I.
    Protein Kinase C-beta Dependent Activation of NF-kappa B in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B-Cells in Vivo
    In: Blood , Jg. 120 2012, Nr. 21, S. 314
  • Sellmann, Ludger; Scholtysik, R.; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Röth, Alexander
    Significance of chromosomal aberrations and HMGA2 expression in Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Onkologie , Jg. 35 2012, Nr. Suppl. 6, S. 220 – 221
  • Harati, Kamran; Chromik, Ansgar Michael; Bulut, D.; Goertz, O.; Hahn, Stephan; Hirsch, Tobias; Klein-Hitpaß, Ludger; Lehnhardt, Marcus; Uhl, Waldemar; Daigeler, Adrien
    TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in HT1080 human fibrosarcoma cells
    In: Anticancer Research , Jg. 32 2012, Nr. 7, S. 2967 – 2984
  • Benisch, Peggy; Schilling, Tatjana; Klein-Hitpaß, Ludger; Frey, Sönke P.; Seefried, Lothar; Raaijmakers, Nadja; Krug, Melanie; Regensburger, Martina; Zeck, Sabine; Schinke, Thorsten; Amling, Michael; Ebert, Regina; Jakob, Franz
    The Transcriptional Profile of Mesenchymal Stem Cell Populations in Primary Osteoporosis Is Distinct and Shows Overexpression of Osteogenic Inhibitors
    In: PLoS ONE , Jg. 7 2012, Nr. 9, S. e45142
    DOI (Open Access)
  • Wirsing, Andrea; Senkel, Sabine; Klein-Hitpaß, Ludger; Ryffel, Gerhart U.
    A Systematic Analysis of the 3′UTR of HNF4A mRNA Reveals an Interplay of Regulatory Elements Including miRNA Target Sites
    In: PLoS ONE , Jg. 6 2011, Nr. 11, S. 0027438
    DOI (Open Access)
  • Mitter, Diana; Ullmann, Reinhard; Muradyan, Artur; Klein-Hitpaß, Ludger; Kanber, Deniz; Õunap, Katrin; Kaulisch, Marc; Lohmann, Dietmar
    Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions
    In: European Journal of Human Genetics , Jg. 19 2011, Nr. 9, S. 947 – 958
    DOI (Open Access)
  • Schwerk, Christian; Adam, Rüdiger; Borkowski, Julia; Schneider, Henriette; Klenk, Michael; Zink, Sascha; Quednau, Natascha; Schmidt, Nicole; Stump, Carolin; Sagar, Anubha; Spellerberg, Barbara; Tenenbaum, Tobias; Koczan, Dirk; Klein-Hitpaß, Ludger; Schroten, Horst
    In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis : release of pro-inflammatory cytokines and chemokines
    In: Microbes and Infection , Jg. 13 2011, Nr. 11, S. 953 – 962
    DOI
  • Gustmann, S.; Klein-Hitpaß, Ludger; Stephan, Harald; Weber, Susanne; Bornfeld, Norbert; Kaulisch, Marc; Lohmann, Dietmar; Dünker, Nicole
    Loss at chromosome arm 16q in retinoblastoma : confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted region
    In: Genes, Chromosomes and Cancer , Jg. 50 2011, Nr. 5, S. 327 – 337
    DOI
  • Saba, Ingrid; Kosan, Christian; Vassen, Lothar; Klein-Hitpaß, Ludger; Möröy, Tarik
    Miz-1 is required to coordinate the expression of TCRβ and p53 effector genes at the pre-TCR "β-selection" checkpoint
    In: The Journal of Immunology (JI) , Jg. 187 2011, Nr. 6, S. 2982 – 2992
    DOI
  • Dürig, Jan; Dührsen, Ulrich; Klein-Hitpaß, Ludger; Worm, J.; Rode Hansen, J.B.; Wissenbach, M.
    The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia
    In: Leukemia , Jg. 25 2011, Nr. 4, S. 638 – 647
    DOI
  • Caliebe, Almuth; Vater, I.; Plendl, Hansjörg; Gesk, Stefan; Siebert, Reiner; Cremer, F. W.; Klein-Hitpaß, Ludger
    A 439 kb-sized homozygous deletion in 17p13.3 leading to biallelic loss of the ASPA as cause of Canavan disease detected by SNP-array analysis : Letter to the Editor
    In: Molecular Genetics and Metabolism , Jg. 99 2010, Nr. 2, S. 184 – 185
    DOI
  • Kosubek, Anna; Klein-Hitpaß, Ludger; Rademacher, Katrin; Horsthemke, Bernhard; Ryffel, Gerhart U.
    Aging of Xenopus tropicalis Eggs Leads to Deadenylation of a Specific Set of Maternal mRNAs and Loss of Developmental Potential
    In: PLoS ONE , Jg. 5 2010, Nr. 10, S. e13532
    DOI, Online Volltext (Open Access)
  • Lanckohr, C.; Kasprzynski, A.; Klein-Hitpaß, Ludger; Homann, H. H.; Lehnhardt, M.; Müller, O.; Kuhnen, C.; Herter, P.
    Erratum zu: Identifikation überexprimierter Gene in myxoid-rundzelligen Liposarkomen. DNA-Mikroarray-Analyse und immunhistochemische Korrelation
    In: Der Pathologe , Jg. 31 2010, Nr. 3, S. 198
    DOI
  • Limbert, Catarina; Ebert, Regina; Schilling, Tatjana; Path, Gunter; Benisch, Peggy; Klein-Hitpaß, Ludger; Seufert, Jochen; Jakob, Franz
    Functional signature of human islet-derived precursor cells compared to bone marrow-derived mesenchymal stem cells
    In: Stem Cells and Development , Jg. 19 2010, Nr. 5, S. 679 – 691
    DOI
  • Sellmann, Ludger; Scholtysik, Rene; Kreuz, Markus; Cyrull, Sandra; Tiacci, Enrico; Stanelle, Jens; Carpinteiro, Alexander; Nückel, Holger; Boes, Tanja; Gesk, Stefan; Siebert, Reiner; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan; Küppers, Ralf
    Gene dosage effects in chronic lymphocytic leukemia
    In: Cancer Genetics and Cytogenetics , Jg. 203 2010, Nr. 2, S. 149 – 160
    DOI
  • Lanckohr, C.; Kasprzynski, Alice; Klein-Hitpaß, Ludger; Homann, Heinz Herbert; Lehnhardt, Marcus; Müller, Oliver; Kuhnen, Cornelius; Herter, Peter
    Identifikation überexprimierter Gene in myxoid-rundzelligen Liposarkomen : DNA-Mikroarray-Analyse und immunhistochemische Korrelation
    In: Der Pathologe , Jg. 31 2010, Nr. 1, S. 60 – 65
    DOI
  • Daigeler, Adrien; Klein-Hitpaß, Ludger; Stricker, Ingo; Müller, Oliver; Kuhnen, Cornelius; Chromik, Ansgar Michael; Steinstraesser, Lars; Goertz, Ole; Steinau, Hans-Ulrich; Lehnhardt, Marcus
    Malignant fibrous histiocytoma-pleomorphic sarcoma, NOS gene expression, histology, and clinical course : A pilot study
    In: Langenbeck's Archives of Surgery , Jg. 395 2010, Nr. 3, S. 261 – 275
    DOI
  • Johansson, Patricia; Eisele, Lewin; Klein-Hitpaß, Ludger; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan; Nückel, Holger
    Percentage of smudge cells determined on routine blood smears is a novel prognostic factor in chronic lymphocytic leukemia
    In: Leukemia Research , Jg. 34 2010, Nr. 7, S. 892 – 898
    DOI
  • Daigeler, Adrien; Chromik, Ansgar M.; Haendschke, Kathrin; Emmelmann, Sabine; Siepmann, Monica; Hensel, Karin; Schmitz, Georg; Klein-Hitpaß, Ludger; Steinau, Hans U.; Lehnhardt, Marcus; Hauser, Joerg
    Synergistic effects of sonoporation and taurolidin/TRAIL on apoptosis in human fibrosarcoma
    In: Ultrasound in Medicine and Biology , Jg. 36 2010, Nr. 11, S. 1893 – 1906
    DOI
  • Schirling, Corinna; Heseding, Christiane; Heise, Franziska; Kesper, Dörthe; Klebes, Ansgar; Klein-Hitpaß, Ludger; Vortkamp, Andrea; Hoffmann, Daniel; Saumweber, Harald; Ehrenhofer-Murray, Ann
    Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60
    In: Chromosoma , Jg. 119 2010, Nr. 1, S. 99 – 113
    DOI
  • Eisele, Lewin; Prinz, Robert; Klein-Hitpaß, Ludger; Nückel, Holger; Lowinksi, Kerstin; Thomale, Jürgen; Möller, Lars; Dührsen, Ulrich; Dürig, Jan
    Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia
    In: European Journal of Haematology , Jg. 83 2009, Nr. 4, S. 320 – 327
    DOI
  • Schulte, Johannes H.; Lim, Soyoung; Schramm, Alexander; Friedrichs, Nicolaus; Koster, Jan; Versteeg, Rogier; Ora, Ingrid; Pajtler, Kristian; Klein-Hitpaß, Ludger; Kuhfittig-Kulle, Steffi; Metzger, Eric; Schüle, Roland; Eggert, Angelika; Buettner, Reinhard; Kirfel, Jutta
    Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : implications for therapy
    In: Cancer Research , Jg. 69 2009, Nr. 5, S. 2065 – 2071
    DOI (Open Access)
  • Bug, Stefanie; Dürig, Jan; Oyen, Florian; Klein-Hitpaß, Ludger; Martin-Subero, Jose; Harder, Lana; Baudis, Michael; Arnold, Norbert; Kordes, Uwe; Dührsen, Ulrich; Schneppenheim, Reinhard; Siebert, Reiner
    Recurrent loss, but lack of mutations, of the SMARCB1 tumor suppressor gene in T-cell prolymphocytic leukemia with TCL1A–TCRAD juxtaposition
    In: Cancer Genetics and Cytogenetics , Jg. 192 2009, Nr. 1, S. 44 – 47
    DOI
  • Edelmann, J.; Klein-Hitpaß, Ludger; Führer, A.; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells
    In: Leukemia Research , Jg. 32 2008, Nr. 10, S. 1565 – 1572
    DOI
  • Schulte, Johannes; Kuhfittig-Kulle, Steffi; Klein-Hitpaß, Ludger; Schramm, Alexander; Biard, Denis S. F.; Pfeiffer, Petra; Eggert, Angelika
    Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cells
    In: DNA Repair , Jg. 7 2008, Nr. 10, S. 1757 – 1764
    DOI
  • Schulte, Johannes; Horn, Sebastian; Otto, Tobias; Samans, Birgit; Heukamp, Lukas C; Eilers, Ursula-Christa; Krause, Michael; Astrahantseff, Kathy; Klein-Hitpaß, Ludger; Buettner, Reinhard; Schramm, Alexander; Christiansen, Holger; Eilers, Martin; Eggert, Angelika; Berwanger, Bernd
    MYCN regulates oncogenic MicroRNAs in neuroblastoma
    In: International Journal of Cancer , Jg. 122 2008, Nr. 3, S. 699 – 704
    DOI
  • Dürig, Jan; Bug, S.; Klein-Hitpaß, Ludger; Boes, Tanja; Jöns, T.; Harder, L.; Baudis, M.; Dührsen, Ulrich; Siebert, Reiner
    Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q11q32)
    In: Leukemia , Jg. 21 2007, Nr. 10, S. 2153 – 2163
    DOI
  • Kuhfittig-Kulle, Steffi; Schulte, J. H.; Mahlow, E.; Klein-Hitpaß, Ludger; Schramm, Alexander; Pfeiffer, P.; Eggert, Angelika
    Neurotrophin receptor status influences the capacity of nonhomologous DNA end joining INSY5Y neuroblastoma cells
    In: Klinische Pädiatrie , Jg. 219 2007, Nr. 3, S. 187 – 187
  • Knauer, Shirley; Krämer, Oliver H.; Knösel, Thomas; Engels, Knut; Rödel, Franz; Kovács, Adorján F.; Dietmaier, Wolfgang; Klein-Hitpaß, Ludger; Habtemichael, Negusse; Schweitzer, Andrea; Brieger, Jürgen; Rödel, Claus; Mann, Wolf; Petersen, Iver; Heinzel, Thorsten; Stauber, Roland H.
    Nuclear export is essential for the tumor-promoting activity of survivin
    In: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 , Jg. 21 2007, Nr. 1, S. 207 – 216
  • Knauer, Shirley; Bier, Carolin; Schlag, Peter; Fritzmann, Johannes; Dietmaier, Wolfgang; Rödel, Franz; Klein-Hitpaß, Ludger; Kovács, Adoriàn F.; Döring, Claudia; Hansmann, Martin-Leo; Hofmann, Wolf-Karsten; Kunkel, Martin; Brochhausen, Christoph; Engels, Knut; Lippert, Burkhard M.; Mann, Wolf; Stauber, Roland H.
    The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex protein
    In: Cell Cycle , Jg. 6 2007, Nr. 12, S. 1502 – 1509
    DOI
  • Hüttmann, Andreas; Klein-Hitpaß, Ludger; Thomale, Jürgen; Deenen, R.; Nückel, Holger; Ebeling, Peter; Führer, A.; Edelmann, J.; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status
    In: Leukemia , Jg. 20 2006, Nr. 10, S. 1774 – 1782
    DOI
  • Nückel, Holger; Hüttmann, Andreas; Klein-Hitpaß, Ludger; Schroers, Roland; Führer, Anja; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Lipoprotein lipase expression is a novel prognostic factor in B-cell chronic lymphocytic leukemia
    In: Leukemia & Lymphoma , Jg. 47 2006, Nr. 6, S. 1053 – 1061
    DOI
  • Schulte, Johannes; Schramm, Alexander; Samans, B.; Krause, M.; Horn, S.; Fagin, A.; Astrahantseff, K.; Klein-Hitpaß, Ludger; Witt, O.; Westermann, F.; Christiansen, H.; Eilers, M.; Berwanger, B.; Eggert, Angelika
    MicroRNA expression analysis in neuroblastoma using pligonuclectide arrays
    In: Klinische Pädiatrie , Jg. 218 2006, Nr. 3, S. 194
  • Pressel, T.; Schramm, Alexander; Schulte, Johannes; Klein-Hitpaß, Ludger; Eggert, Angelika
    Microarray analysis defines IPL/TSSC3 as a potential target mediating the synergistic effects of combined thermo-chemotherapy in neuroblastoma cells
    In: Klinische Pädiatrie , Jg. 218 2006, Nr. 3, S. 192 – 193
    DOI
  • Schroers, R.; Griesinger, F.; Trümper, L.; Haase, D.; Kulle, B.; Klein-Hitpaß, Ludger; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia
    In: Leukemia , Jg. 19 2005, Nr. 5, S. 750 – 758
    DOI
  • Grasemann, Corinna; Gratias, S.; Stephan, H.; Schüler, A.; Schramm, Alexander; Klein-Hitpaß, Ludger; Rieder, H.; Schneider, S.; Kappes, F.; Eggert, Angelika; Lohmann, Dietmar
    Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma
    In: Oncogene , Jg. 24 2005, Nr. 42, S. 6441 – 6449
    DOI
  • Gashaw, Isabella; Grümmer, Ruth; Klein-Hitpaß, Ludger; Dushaj, O.; Bergmann, M.; Brehm, R.; Grobholz, R.; Kliesch, S.; Neuvians, T.P.; Schmid, Kurt Werner; Von Ostau, C.; Winterhager, Elke
    Gene signatures of testicular seminoma with emphasis on expression of ets variant gene 4
    In: Cellular and Molecular Life Sciences - CMLS , Jg. 62 2005, Nr. 19-20, S. 2359 – 2368
    DOI
  • Schulte, Johannes; Schramm, Alexander; Klein-Hitpaß, Ludger; Klenk, M.; Wessels, H.; Hauffa, Berthold; Eils, J.; Eils, R.; Brodeur, G. M.; Schweigerer, L.; Havers, Werner; Eggert, Angelika
    Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas
    In: Oncogene , Jg. 24 2005, Nr. 1, S. 165 – 177
  • Schramm, Alexander; Schulte, Johannes; Klein-Hitpaß, Ludger; Havers, Werner; Sieverts, H.; Berwanger, B.; Christiansen, H.; Warnat, P.; Brors, B.; Eils, J.; Eils, R.; Eggert, Angelika
    Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling
    In: Oncogene , Jg. 24 2005, Nr. 53, S. 7902 – 7912
    DOI
  • Dürig, Jan; Nückel, Holger; Hüttmann, Andreas; Kruse, Elisabeth; Hölter, Tanja; Halfmeyer, Katja; Führer, Anja; Rudolph, Roland; Kalhori, Nasa; Nusch, Arnd; Deaglio, Silvia; Malavasi, Fabio; Möröy, Tarik; Klein-Hitpaß, Ludger; Dührsen, Ulrich
    Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia
    In: Blood , Jg. 101 2003, Nr. 7, S. 2748 – 2755
    DOI
  • Schulte, Johannes; Schramm, Alexander; Pressel, T.; Klein-Hitpaß, Ludger; Kremens, Bernhard; Eils, J.; Havers, Werner; Eggert, Angelika
    Microarray-analysis : a new approach to study the molecular mechanisms of thermo-chemotherapy
    In: Klinische Pädiatrie , Jg. 215 2003, Nr. 6, S. 298 – 302
    DOI
  • Dürig, Jan; Nückel, Holger; Cremer, M.; Führer, A.; Halfmeyer, K.; Fandrey, Joachim; Möröy, Tarik; Klein-Hitpaß, Ludger; Dührsen, Ulrich
    ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia
    In: Leukemia , Jg. 17 2003, Nr. 12, S. 2426 – 2434
    DOI
  • Klein-Hitpaß, Ludger; Möröy, Tarik
    Der Biochip : Neue Horizonte in Prävention, Diagnose und Nachsorge von Tumorerkrankungen
    In: Essener Unikate: Berichte aus Forschung und Lehre 2001, Nr. 15 : Klinische Onkologie – Fortschritte in der Behandlung von Krebserkrankungen, S. 12 – 19
    Online Volltext (Open Access)

    • Abstracts

  • Lollies, A; Schneider, M; Hartmann, S; Weniger, Marc; Tiacci, E; Johansson, Patricia; Klein-Hitpaß, Ludger; Hansmann, ML; Küppers, Ralf
    Molecular Mechanisms in the Pathogenesis of Composite Lymphomas
    4th International Symposium on Childhood, Adolescent and Young Adult Hodgkin Lymphoma, ISCAYAHL 2020, 13 - 16 May 2020, Berlin, Germany,
    In: Klinische Pädiatrie , Jg. 232 2020, Nr. 02, S. 80
    DOI
  • Hack, Theresa; Bertram, Stefanie; Büsche, Guntram; Hanenberg, Helmut; Klein-Hitpaß, Ludger; Von Neuhoff, Nils; Reinhardt, Dirk; Schneider, Markus; Rasche, Mareike
    Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia : Results of an in Vitro and In Vivo Analysis
    61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,
    In: Blood , Jg. 134 2019, Nr. Supplement_1, S. 3734 – 3734
    DOI (Open Access)
  • Chen, Yiyang; Zaun, Yasmin; Arnold, Lucas; Weissenfels, Kerstin; Schmid, Kurt Werner; Klein-Hitpaß, Ludger; Squire, Anthony; Bertram, Stefanie; Duehrsen, Ulrich; Hanoun, Maher
    Acute Myeloid Leukemia Induced Remodelling of the Human Bone Marrow Niche Predicts Clinical Outcome
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood , Jg. 132 2018, Nr. Supplement 1, S. 3851 – 3851
    DOI (Open Access)
  • Johansson, Patricia; Habenberger, Peter; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Küppers, Ralf; Schultz-Fademrecht, Carsten; Choidas, Axel; Dürig, Jan
    CDK9 Inhibition with LDC526 Is an Effective Treatment for T-Cell Prolymphocytic Leukemia (T-PLL) in Vitro
    In: Blood , Jg. 130 2017, Nr. Suppl. 1, S. 1262
    DOI
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Bergmann, A.; Siebert, R.; Scholtysik, R.; Przekopowitz, M.; Seifert, M.; Zenz, T.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Genomic profiling of T-cell Prolymphocytic Leukemia (T-PLL) identifies novel recurrent mutations in SAMHD1 and PTPRC
    Jahrestagung der ­Deutschen, Österreichischen und ­Schweizerischen ­Gesellschaften für Hämatologie und ­Medizinische Onkologie, Leipzig, 14.–18. Oktober 2016,
    In: Oncology Research and Treatment , Jg. 39 2016, Nr. Suppl. 3, S. 238 – 238
    DOI
  • Lollies, A.; Hartmann, S.; Schneider, M.; Bracht, T.; Arnolds, Judith; Klein-Hitpaß, Ludger; Sitek, B.; Hansmann, M. L.; Küppers, Ralf; Weniger, Marc
    The AP-1 transcription factor BATF3 regulates MYC expression and is required for tumor cell survival in classical Hodgkin lymphoma and anaplastic large cell lymphoma
    In: Haematologica / The Hematology Journal , Jg. 101 2016, Nr. S 5: You have access 10th International Symposium on Hodgkin Lymphoma, Cologne, Germany, October 22–25, 2016, Abstract Book, S. 2
    (Open Access)
  • Stuschke, Martin; Sak, Ali; Abu Jawad, Jehad; Bachmann, H. S.; Tinhofer, I.; Budach, V.; Baumann, M.; Krause, M.; Lohaus, F.; Linge, A.; Gkika, E.; Balermpas, P.; Roedel, C.; Avlar, M.; Grosu, A. L.; Abdollahi, A.; Debus, J.; Bayer, C.; Belka, C.; Pigorsch, S.; Combs, S. E.; Moennich, D.; Zips, D.; Lang, Stephan; Klein-Hitpaß, Ludger
    Einzelnukleotid Polymorphismen in Reparaturproteinen sind prognoserelevant für des Überleben von Kopf-Hals-Tumorpatienten nach postoperativer Radiochemotherapie mit Cisplatin (DKTK-ROG)
    21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 191 2015, Nr. Suppl. 1 , S. 28 - S. 29
    DOI
  • Matschke, Johann; Riffkin, H.; Handrick, R.; Klein-Hitpaß, Ludger; Jendrossek, Verena
    Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell death
    In: European Journal of Cancer (EJC) , Jg. 50 2014, Nr. Suppl. 5, S. 51
    DOI
  • Benisch, P.; Frey, S.; Seefried, Lothar; Klein-Hitpaß, Ludger; Ebert, R.; Jakob, F.
    The transcriptome of hMSC from osteoporotic donors is distinct from hMSC of 80+ donors
    ECTS 2012, 39th Annual Congress; 19-23 May 2012; Stockholm, Sweden,
    In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) , Jg. 50 2012, Nr. Suppl. 1, S. S83
    DOI
  • Ebert, R.; Meissner-Weigl, J.; Zeck, S.; Klein-Hitpaß, Ludger; Rachner, T.; Benad, P.; Hofbauer, L.; Jakob, F.
    Modulation of Proliferation in MCF7 Cells by Regulated Expression of KLF2, 4, 6 and Ki-67 After Treatment With Zoledronic Acid
    In: European Journal of Cancer (EJC) , Jg. 47 2011, Nr. Suppl. 1, S. 359
    DOI
  • Göbel, M.; Eisele, Lewin; Huttmann, A.; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan
    Progranulin plasma levels predict time to first treatment and overall survival in chronic lymphocytic leukemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie , Jg. 34 2011, Nr. Suppl. 6, S. 196 – 196
    DOI
  • Gigel, C.; Eisele, Lewin; Mollmann, M.; Klein-Hitpaß, Ludger; Koch, T.; Hansen, JBR; Orum, H.; Wissenbach, M.; Dührsen, Ulrich; Dürig, Jan
    Comparing the pharmacological effects of the novel Locked Nucleic Acid (LNA) modified antisense Bcl-2 inhibitor SPC2996 and G3139 (oblimersen) in preclinical models of chronic lymphocytic leukemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie , Jg. 33 2010, Nr. Suppl. 6, S. 184
    DOI
  • Hanoun, Maher; Klein-Hitpaß, Ludger; Eisele, Lewin; Duhrsen, U.; Durig, J.
    Cryptochrome 1 (CRY1) promoter methylation is associated with good prognosis in B-cell chronic lymphocytic leukemia (CLL)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie , Jg. 33 2010, Nr. Suppl. 6, S. 240 – 241
    DOI
  • Gothert, J. R.; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Fuhrer, A.; Sellmann, Ludger; Roth, A.; Pircher, H.; Duhrsen, U.; Dürig, Jan
    Expanded CD8(+) T-cells of murine and human B-CLL are driven into a senescent KLRG1(+) effector memory phenotype
    In: Onkologie , Jg. 33 2010, Nr. Suppl. 6, S. 201
    DOI
  • Gothert, Joachim Rudolf; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Fuhrer, Anja; Sellmann, Ludger; Röth, Alexander; Dührsen, Ulrich; Pircher, Hanspeter; Dürig, Jan
    Expanded CLL CD8(+) T-Cells Are Driven Into a Senescent KLRG1(+) Effector Memory Phenotype
    In: Blood , Jg. 116 2010, Nr. 21, S. 403
  • Johansson, Patricia; Hollenbeck, Anita; Klein-Hitpaß, Ludger; de Dechene, Maldonado E; Eisele, Lewin; Kieruzel, Sabrina; Horn, Peter; Schmücker, Ute; Vetter, Ina; Gerken, Guido; Dührsen, Ulrich; Dürig, Jan; Schlaak, Jörg Friedrich
    Prevalence of B cell lymphoproliferative disorders in patients with chronic hepatitis C (CHC)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010, pp 109–206,
    In: Onkologie , Jg. 33 2010, Nr. Suppl. 6, S. 157
    DOI
  • Dürig, Jan; Klein-Hitpaß, Ludger; Worm, J.; Hansen, JBR; Orum, H.; Dührsen, U.; Wissenbach, M.
    The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie , Jg. 33 2010, Nr. Suppl. 6, S. 42
    DOI

    • Beiträge in Sammelwerken und Tagungsbänden

  • Leitão, Elsa; Beygo, Jasmin; Zeschnigk, Michael; Klein-Hitpaß, Ludger; Bargull, Marcel; Rahmann, Sven; Horsthemke, Bernhard
    Locus-specific DNA methylation analysis by targeted deep bisulfite sequencing
    In: Epigenome Editing: Methods and Protocols / Jeltsch, Albert; Rots, Marianne G. (Hrsg.) 2018, S. 351 – 366
    DOI

    • Poster / Posterbeiträge

  • Johansson, Patricia; Dierichs, L.; Klein-Hitpaß, Ludger; Bergmann, A.; Menninger, S.; Habenberger, P.; Klebl, B.; Siveke, Jens; Dührsen, U.; Choidas, A.; Dürig, Jan
    Anti-leukemic activity through CDK9 inhibition in T-cell prolymphocytic leukemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment , Jg. 42 2019, Nr. Supplement 4: Abstracts, S. 218
    DOI (Open Access)