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Funktionen

  • apl. Professor/in und Privatdozent/in, Institut für Zellbiologie (Tumorforschung)

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Johansson, Patricia; Klein-Hitpaß, Ludger; Budeus, Bettina; Kuhn, Matthias; Lauber, Chris; Seifert, Michael; Roeder, Ingo; Pförtner, Roman; Stuschke, Martin; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencing
    In: Cancers Jg. 12 (2020) Nr. 4, S. 986
    ISSN: 2072-6694
  • Kehrmann, Jan; Effenberg, Laura; Wilk, Camilla; Schoemer, Davina; Ngo Thi Phuong, Nhi; Adamczyk, Alexandra; Pastille, Eva; Scholtysik, René; Klein-Hitpaß, Ludger; Klopfleisch, Robert; Westendorf, Astrid; Buer, Jan
    Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome
    In: Immunology (2019)
    ISSN: 1365-2567; 0019-2805
  • Kalmbach, Alexander; Schröder, Christopher; Klein-Hitpaß, Ludger; Nordström, Karl; Ulz, Peter; Heitzer, Ellen; Speicher, Michael R.; Rahmann, Sven; Wieczorek, Dagmar; Horsthemke, Bernhard; Bramswig, Nuria C.
    Genome-wide analysis of the nucleosome landscape in individuals with coffin-siris syndrome
    In: Cytogenetic and Genome Research Jg. 159 (2019) S. 1 - 11
    ISSN: 1424-859X; 1424-8581
  • Kehrmann, Jan; Menzel, Jannis; Saeedghalati, Mohammadkarim; Obeid, Rima; Schulze, Christina; Holzendorf, Volker; Farahpour, Farnoush; Reinsch, Nico; Klein-Hitpaß, Ludger; Streeck, Hendrik; Hoffmann, Daniel; Buer, Jan; Esser, Stefan
    Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart Disease
    In: The Journal of Infectious Diseases Jg. 219 (2019) Nr. 3, S. 497 - 508
    ISSN: 1537-6613; 0022-1899
  • Jünger, Stephanie T.; Mynarek, Martin; Wohlers, Inken; Dörner, Evelyn; Mühlen, Anja Zur; Velez-Char, Natalia; Von Hoff, Katja; Rutkowski, Stefan; Warmuth-Metz, Monika; Kortmann, Rolf-Dieter; Timmermann, Beate; Rahmann, Sven; Klein-Hitpaß, Ludger; Von Bueren, Andre O.; Pietsch, Torsten
    Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohort
    In: Acta Neuropathologica Communications Jg. 7 (2019) Nr. 1, S. 181
    ISSN: 2051-5960
  • Lollies, Anna; Hartmann, Sylvia; Schneider, Markus; Bracht, Thilo; Weiß, A.L.; Arnolds, Judith; Klein-Hitpaß, Ludger; Sitek, Barbara; Hansmann, Martin Leo; Küppers, Ralf; Weniger, Marc
    An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphoma
    In: Leukemia Jg. 32 (2018) Nr. 1, S. 92 - 101
    ISSN: 0887-6924; 1476-5551
  • Tucci, Felicia A.; Kitanovski, Simo; Johansson, Patricia; Klein-Hitpaß, Ludger; Kahraman, Alisan; Dürig, Jan; Hoffmann, Daniel; Küppers, Ralf
    Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individuals
    In: Blood Jg. 131 (2018) Nr. 5, S. 546 - 557
    ISSN: 1528-0020; 0006-4971
  • Mangolini, Maurizio; Götte, Frederik; Moore, Andrew; Ammon, Tim; Oelsner, Madlen; Lutzny-Geier, Gloria; Klein-Hitpaß, Ludger; Williamson, James C.; Lehner, Paul J.; Dürig, Jan; Möllmann, Michael; Rásó-Barnett, Lívia; Hughes, Katherine; Santoro, Antonella; Méndez-Ferrer, Simón; Oostendorp, Robert A. J.; Zimber-Strobl, Ursula; Peschel, Christian; Hodson, Daniel J.; Schmidt-Supprian, Marc; Ringshausen, Ingo
    Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia
    In: Nature Communications Jg. 9 (2018) S. 3839
    ISSN: 2041-1723
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Choidas, Axel; Habenberger, Peter; Mahboubi, Bijan; Kim, Baek; Bergmann, Anke; Scholtysik, René; Brauser, Martina; Lollies, Anna; Siebert, Reiner; Zenz, Thorsten; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia
    In: Blood Cancer Journal Jg. 8 (2018) Nr. 1, S. 11
    ISSN: 2044-5385
  • Hendgen-Cotta, Ulrike B.; Esfeld, Sonja; Coman, Cristina; Ahrends, Robert; Klein-Hitpaß, Ludger; Flögel, Ulrich; Rassaf, Tienush; Totzeck, Matthias
    A novel physiological role for cardiac myoglobin in lipid metabolism
    In: Scientific Reports Jg. 7 (2017) S. 43219
    ISSN: 2045-2322
  • Sucker, Antje; Zhao, Fang; Pieper, Natalia; Heeke, Christina; Maltaner, Raffaela; Stadtler, Nadine; Real, Birgit; Bielefeld, Nicola; Howe, Sebastian; Weide, Benjamin; Gutzmer, Ralf; Utikal, Jochen; Loquai, Carmen; Gogas, Helen; Klein-Hitpaß, Ludger; Zeschnigk, Michael; Westendorf, Astrid; Trilling, Mirko; Horn, Susanne; Schilling, Bastian; Schadendorf, Dirk; Griewank, Klaus; Paschen, Annette
    Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesions
    In: Nature Communications Jg. 8 (2017) S. 15440
    ISSN: 2041-1723
  • Johansson, Patricia; Habenberger, Peter; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Küppers, Ralf; Schultz-Fademrecht, Carsten; Choidas, Axel; Dürig, Jan
    CDK9 Inhibition with LDC526 Is an Effective Treatment for T-Cell Prolymphocytic Leukemia (T-PLL) in Vitro
    In: Blood Jg. 130 (2017) Nr. Suppl. 1, S. 1262
    ISSN: 0006-4971; 1528-0020
  • Wöchtl, Bettina; Gunzer, Florian; Gerner, Wilhelm; Gasse, Hagen; Koch, Michaela; Bagó, Zoltán; Ganter, Martin; Weissenböck, Herbert; Dinhopl, Nora; Coldewey, Sina M.; Von Altrock, Alexandra; Waldmann, Karl-Heinz; Saalmüller, Armin; Zimmermann, Kurt; Steinmann, Jörg; Kehrmann, Jan; Klein-Hitpaß, Ludger; Blom, Jochen; Ehricht, Ralf; Engelmann, Ines; Hennig-Pauka, Isabel
    Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7
    In: Gut Pathogens Jg. 9 (2017) S. 30
    ISSN: 1757-4749
  • Pohl, Judith-Mira; Gutweiler, Sebastian; Thiebes, Stephanie; Volke, Julia K.; Klein-Hitpaß, Ludger; Zwanziger, Denise; Gunzer, Matthias; Jung, Steffen; Agace, William W.; Kurts, Christian; Engel, Daniel Robert
    Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus
    In: Gut Jg. 66 (2017) Nr. 12, S. 2110 - 2120
    ISSN: 1468-3288; 0017-5749
  • Mangolini, M.; Gotte, F.; Ammon, T.; Oelsner, M.; Klein-Hitpaß, Ludger; Dürig, Jan; Hughes, K.; Lutzny, G.; Strobl, U.; Ringshausen, I.
    NOTCH-signaling in the tumor microenvironment is required for canonical WNT signaling in CLL cells
    In: Leukemia and Lymphoma Jg. 58 (2017) Nr. Suppl. 1, XVII International Workshop on Chronic Lymphocytic Leukemia 2017 May 12--15, 2017, New York, S. 125 - 126
    ISSN: 1042-8194; 1029-2403
  • Hönes, Georg Sebastian; Rakov, Helena; Logan, John; Liao, Xiao-Hui; Werbenko, Eugenie; Pollard, Andrea S.; Praestholm, Stine M.; Siersbaek, Majken S.; Rijntjes, Eddy; Gassen, Janina; Latteyer, Soren; Engels, Kathrin; Strucksberg, Karl-Heinz; Kleinbongard, Petra; Zwanziger, Denise; Rozman, Jan; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Klein-Hitpaß, Ludger; Köhrle, Josef; Armstrong, David L.; Grontved, Lars; Bassett, J. H. Duncan; Williams, Graham R.; Refetoff, Samuel; Führer, Dagmar; Möller, Lars
    Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 114 (2017) Nr. 52, S. E11323 - E11332
    ISSN: 1091-6490; 0027-8424
  • Japp, Anna Sophia; Klein-Hitpaß, Ludger; Denkhaus, Dorota; Pietsch, Torsten
    OTX2 defines a subgroup of atypical teratoid rhabdoid tumors with close relationship to choroid plexus tumors
    In: Journal of Neuropathology & Experimental Neurology Jg. 76 (2017) Nr. 1, S. 32 - 38
    ISSN: 1554-6578; 0022-3069
  • Schröder, Christopher; Leitão, Elsa; Wallner, Stefan; Schmitz, Gerd; Klein-Hitpaß, Ludger; Sinha, Anupam; Jöckel, Karl-Heinz; Heilmann-Heimbach, Stefanie; Hoffmann, Per; Nöthen, Markus M.; Steffens, Michael; Ebert, Peter; Rahmann, Sven; Horsthemke, Bernhard
    Regions of common inter-individual DNA methylation differences in human monocytes: Genetic basis and potential function
    In: Epigenetics and Chromatin Jg. 10 (2017) Nr. 1, S. 37
    ISSN: 1756-8935
  • Kehrmann, Jan; Veckollari, B.; Schmidt, Dirk; Schildgen, Oliver; Schildgen, Verena; Wagner, N.; Zeschnigk, Michael; Klein-Hitpaß, Ludger; Witzke, Oliver; Buer, Jan; Steinmann, Jörg
    The lung microbiome in patients with pneumocystosis
    In: BMC Pulmonary Medicine Jg. 17 (2017) Nr. 1, S. 170
    ISSN: 1471-2466
  • Latteyer, Sören; Möller, Lars; Führer, Dagmar; Schmid, Kurt Werner; Pöppel, Thorsten; Khandanpour, Cyrus; Klein-Hitpaß, Ludger; Zwanziger, Denise
    A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A
    In: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 101 (2016) Nr. 3, S. 1016 - 1022
    ISSN: 1945-7197
  • Fielitz, Kathrin; Althoff, Kristina; De Preter, Katleen; Nonnekens, Julie; Ohli, Jasmin; Elges, Sandra; Hartmann, Wolfgang; Klöppel, Günter; Knösel, Thomas; Schulte, Marc; Klein-Hitpaß, Ludger; Beisser, Daniela; Reis, Henning; Eyking, Annette; Cario, Elke; Schulte, Johannes; Schramm, Alexander; Schüller, Ulrich
    Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells
    In: OncoTarget Jg. 7 (2016) Nr. 46, S. 74415 - 74426
    ISSN: 1949-2553
  • Wallner, Stefan; Schröder, Christopher; Leitão, Elsa; Berulava, Tea; Haak, Claudia; Beisser, Daniela; Rahmann, Sven; Richter, Andreas S.; Manke, Thomas; Bönisch, Ulrike; Arrigoni, Laura; Fröhler, Sebastian; Klironomos, Filippos; Chen, Wei; Rajewsky, Nikolaus; Müller, Fabian; Ebert, Peter; Lengauer, Thomas; Barann, Matthias; Rosenstiel, Philip; Gasparoni, Gilles; Nordström, Karl; Walter, Jörn; Brors, Benedikt; Zipprich, Gideon; Felder, Bärbel; Klein-Hitpaß, Ludger; Attenberger, Corinna; Schmitz, Gerd; Horsthemke, Bernhard
    Epigenetic dynamics of monocyte-to-macrophage differentiation
    In: Epigenetics and Chromatin Jg. 9 (2016) S. 33
    ISSN: 1756-8935
  • Hönes, J M; Botezatu, L; Helness, A; Vadnais, C; Vassen, L; Robert, F; Hergenhan, S M; Thivakaran, A; Schütte, J; Al-Matary, Y S; Lams, R F; Fraszscak, J; Makishima, H; Radivoyevitch, T; Przychodzen, B; da Conceição Castro, S V; Görgens, A; Giebel, Bernd; Klein-Hitpaß, Ludger; Lennartz, K; Heuser, M; Thiede, C; Ehninger, G; Dührsen, Ulrich; Maciejewski, J; Möröy, T; Khandanpour, Cyrus
    GFI1 as a novel prognostic and therapeutic factor for AML/MDS
    In: Leukemia Jg. 30 (2016) Nr. 6, S. 1237 - 1245
    ISSN: 0887-6924; 1476-5551
  • Naschberger, Elisabeth; Liebl, Andrea; Schellerer, Vera S; Schütz, Manuela; Britzen-Laurent, Nathalie; Kölbel, Patrick; Schaal, Ute; Haep, Lisa; Regensburger, Daniela; Wittmann, Thomas; Klein-Hitpaß, Ludger; Rau, Tilman T; Dietel, Barbara; Méniel, Valérie S; Clarke, Alan R; Merkel, Susanne; Croner, Roland S; Hohenberger, Werner; Stürzl, Michael
    Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma
    In: The Journal of Clinical Investigation (JCI) Jg. 126 (2016) Nr. 11, S. 4187 - 4204
    ISSN: 0021-9738
  • Johansson, Patricia; Bergmann, Anke; Rahmann, Sven; Wohlers, Inken; Scholtysik, René; Przekopowitz, Martina; Seifert, Marc; Tschurtschenthaler, Gertraud; Webersinke, Gerald; Jäger, Ulrich; Siebert, Reiner; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan; Küppers, Ralf
    Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia
    In: International Journal of Cancer Jg. 138 (2016) Nr. 1, S. 121 - 124
    ISSN: 0020-7136; 1097-0215
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Grabellus, Florian; Arnold, Georg; Klapper, Wolfram; Pförtner, Roman; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas
    In: OncoTarget Jg. 7 (2016) Nr. 38, S. 62627 - 62639
    ISSN: 1949-2553
  • Sellmann, Ludger; Scholtysik, Rene; de Beer, Dirk; Eisele, Lewin; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Düring, Jan; Röth, Alexander; Baerlocher, Gabriele
    Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia
    In: Leukemia and Lymphoma Jg. 57 (2016) Nr. 3, S. 590 - 595
    ISSN: 1029-2403
  • Althoff, K; Beckers, A; Bell, E; Nortmeyer, M; Thor, T; Sprüssel, A; Lindner, S; De Preter, K; Florin, A; Heukamp, L C; Klein-Hitpaß, Ludger; Astrahantseff, K; Kumps, C; Speleman, F; Eggert, A; Westermann, F; Schramm, Alexander; Schulte, Johannes
    A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
    In: Oncogene Jg. 34 (2015) Nr. 26, S. 3357 - 3368
    ISSN: 0950-9232; 1476-5594
  • Lindner, Sven; Bachmann, Hagen Sjard; Odersky, Andrea; Schaefers, Simon; Klein-Hitpaß, Ludger; Hero, Barbara; Fischer, Matthias; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma
    In: Biomedical Reports Jg. 3 (2015) Nr. 4, S. 443 - 446
    ISSN: 2162-4178; 2049-9442
  • Pettirossi, Valentina; Santi, Alessia; Imperi, Elisa; Russo, Guido; Pucciarini, Alessandra; Bigerna, Barbara; Schiavoni, Gianluca; Fortini, Elisabetta; Spanhol-Rosseto, Ariele; Sportoletti, Paolo; Mannucci, Roberta; Martelli, Maria P.; Klein-Hitpaß, Ludger; Falini, Brunangelo; Tiacci, Enrico
    BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity
    In: Blood Jg. 125 (2015) Nr. 8, S. 1207 - 1216
    ISSN: 0006-4971; 1528-0020
  • Steinert, Andre F.; Kunz, Manuela; Prager, Patrick; Göbel, Sascha; Klein-Hitpaß, Ludger; Ebert, Regina; Nöth, Ulrich; Jakob, Franz; Gohlke, Frank
    Characterization of bursa subacromialis-derived mesenchymal stem cells
    In: Stem Cell Research & Therapy Jg. 6 (2015) S. 114
    ISSN: 1757-6512
  • Britzen-Laurent, Nathalie; Naschberger, Elisabeth; Rau, Tilman T.; Dietel, Barbara; Klein-Hitpaß, Ludger; Stürzl, Michael; Liebl, Andrea; Grenz, Sandra; Hohenberger, Werner; Schaal, Ute; Merkel, Susanne; Schellerer, Vera S.; Croner, Roland S.; Kölbel, Patrick
    Endothelial cells isolated from colorectal carcinoma exhibit tumor microenvironment-dependent plasticity allowing the identification of SPARCL1 as a novel endothelial cell quiescence factor
    In: Cancer Research Jg. 75 (2015) Nr. 15 Suppl., S. 2375
    ISSN: 0008-5472
  • Jeruschke, Stefanie; Jeruschke, Kay; DiStasio, Andrew; Karaterzi, Sinem; Büscher (A.), Anja; Nalbant, Perihan; Klein-Hitpaß, Ludger; Hoyer, Peter Friedrich; Weiss, Jürgen; Stottmann, Rolf W; Weber, Stefanie
    Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression
    In: PLoS One Jg. 10 (2015) Nr. 9, S. e0137043
    ISSN: 1932-6203
  • Li, Yu; Dürig, Jan; Göbel, Maria; Hanoun, Maher; Klein-Hitpaß, Ludger; Dührsen, Ulrich
    Functional abnormalities and changes in gene expression in fibroblasts and macrophages from the bone marrow of patients with acute myeloid leukemia
    In: International Journal of Hematology Jg. 102 (2015) Nr. 3, S. 278 - 288
    ISSN: 1865-3774; 0925-5710
  • Japp, Anna Sophia; Gessi, Marco; Messing-Jünger, Martina A.; Denkhaus, Dorata; Zur Mühlen, Anja; Wolff, Johannes Ernst; Hartung, Stefan; Kordes, Uwe; Klein-Hitpaß, Ludger; Pietsch, Thorsten
    High-Resolution Genomic Analysis Does Not Qualify Atypical Plexus Papilloma as a Separate Entity Among Choroid Plexus Tumors
    In: Journal of Neuropathology & Experimental Neurology Jg. 74 (2015) Nr. 2, S. 110 - 120
    ISSN: 0022-3069
  • Büchel, Janine; Bartosova, Maria; Eich, Gwendolyn; Wittenberger, Timo; Klein-Hitpaß, Ludger; Steppan, Sonja; Hackert, Thilo; Schaefer, Franz; Passlick-Deetjen, Jutta; Schmitt, Claus P.
    Interference of peritoneal dialysis fluids with cell cycle mechanisms
    In: Peritoneal Dialysis International Jg. 35 (2015) Nr. 3, S. 259 - 274
    ISSN: 0896-8608
  • Berulava, Tea; Rahmann, Sven; Rademacher, Katrin; Klein-Hitpass, Ludgar; Horsthemke, Bernhard
    N6-Adenosine Methylation in MiRNAs
    In: PLoS One Jg. 10 (2015) Nr. 2, S. e0118438
    ISSN: 1932-6203
  • Graser, Stephanie; Mentrup, Birgit; Schneider, Doris; Klein-Hitpaß, Ludger; Jakob, Franz; Hofmann, Christine
    Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line
    In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 79 (2015) S. 150 - 161
    ISSN: 1873-2763; 8756-3282
  • Harati, Kamran; Slodnik, Pawel; Chromik, Ansgar M.; Behr, Björn; Goertz, Ole; Hirsch, Tobias; Kapalschinski, Nicolai; Klein-Hitpaß, Ludger; Kolbenschlag, Jonas; Uhl, Waldemar; Lehnhardt, Marcus; Daigeler, Adrien
    Pro-apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cells
    In: International Journal of Oncology Jg. 46 (2015) Nr. 4, S. 1629 - 1636
    ISSN: 1019-6439
  • Harati, Kamran; Slodnik, Pawel; Chromik, Ansgar Michael; Goertz, Ole; Hirsch, Tobias; Kapalschinski, Nikolai; Klein-Hitpaß, Ludger; Kolbenschlag, Jonas; Uhl, Waldemar; Lehnhardt, Marcus; Daigeler, Adrien
    Resveratrol induces apoptosis and alters gene expression in human fibrosarcoma cells
    In: Anticancer Research Jg. 35 (2015) Nr. 2, S. 767 - 774
    ISSN: 0250-7005
  • Schröder, Wiebke; Bernhardt, Jörg; Marincola, Gabriella; Klein-Hitpaß, Ludger; Herbig, Alexander; Krupp, Guido; Nieselt, Kay; Wolz, Christiane
    Altering gene expression by aminocoumarins : The role of DNA supercoiling in Staphylococcus aureus
    In: BMC Genomics Jg. 15 (2014) Nr. 1, S. 291
    ISSN: 1471-2164
  • Matschke, Johannes; Riffkin, H.; Handrick, R.; Klein-Hitpaß, Ludger; Jendrossek, Verena
    Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell death
    In: European Journal of Cancer Jg. 50 (2014) Nr. Suppl. 5, S. 51
    ISSN: 0959-8049
  • Jeruschke, Stefanie; Rekasi, Heike; Karaterzi, Sinem; Buescher, AnjaKarin; Klein-Hitpaß, Ludger; Jeruschke, Kay; Weiss, Juergen; Saleem, MoinAhson; Hoyer, Peter Friedrich; Nalbant, Perihan; Weber, Stefanie
    Everolimus Prevents Podocyte Injury Via Stabilizing Tubb2b And Dcdc2 Expression
    In: Pediatric Nephrology Jg. 29 (2014) Nr. 9, S. 1674 - 1674
    ISSN: 0931-041X
  • Rademacher, Katrin; Schröder, Christopher; Kanber, Deniz; Klein-Hitpaß, Ludger; Wallner, Stefan; Zeschnigk, Michael; Horsthemke, Bernhard
    Evolutionary origin and methylation status of human intronic CpG islands that are not present in mouse
    In: Genome Biology and Evolution Jg. 6 (2014) Nr. 7, S. 1579 - 1588
    ISSN: 1759-6653
  • Japp, Anna; Gessi, Marco; zur Muehlen, Anja; Klein-Hitpaß, Ludger
    Genome-wirde DNA copy number analysis of choroid plexus tumors
    In: Neuro-Oncology Jg. 16 (2014) Nr. Suppl. 1, S. 134
    ISSN: 1522-8517; 1523-5866
  • Japp, A. S.; Gessi, M.; Denkhaus, D.; zur Muehlen, A.; Pietsch, T.; Hartung, S.; Kordes, U.; Messing-Juenger, M.; Wolff, J. E.; Klein-Hitpaß, Ludger
    High-resolution genomic analysis of choroid plexus tumors separates two genetic entities and identifies recurrent focal alterations
    In: Brain Pathology Jg. 24 (2014) Nr. Suppl. 1, S. 73 - 74
    ISSN: 1015-6305
  • Liedert, Astrid; Röntgen, Viktoria; Schinke, Thorsten; Benisch, Peggy; Ebert, Regina; Jakob, Franz; Klein-Hitpaß, Ludger; Lennerz, Jochen K.; Amling, Michael; Ignatius, Anita
    Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in Mice
    In: PLoS One Jg. 9 (2014) Nr. 7, S. e103250
    ISSN: 1932-6203
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Dörner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-?B signaling pathway
    In: Acta Neuropathologica Jg. 127 (2014) Nr. 4, S. 609 - 611
    ISSN: 0001-6322; 1432-0533
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Doerner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95-rela fusions leading to activation of the NF-KB signalling pathway
    In: Neuro-Oncology Jg. 16 (2014) Nr. Suppl. 1, S. i24
    ISSN: 1522-8517; 1523-5866
  • Pietsch, Torsten; Wohlers, Inken; Goschzik, Tobias; Dreschmann, Verena; Denkhaus, Dorota; Dörner, Evelyn; Rahmann, Sven; Klein-Hitpaß, Ludger
    Supratentorial ependymomas of childhood carry C11orf95–RELA fusions leading to pathological activation of the NF-κB signaling pathway
    In: Acta Neuropathologica Jg. 127 (2014) Nr. 4, S. 609 - 611
    ISSN: 0001-6322; 1432-0533
  • Santi, A.; Pettirossi, V.; Imperi, E.; Russo, G.; Pucciarini, A.; Bigerna, B.; Fortini, E.; Mannucci, R.; Schiavoni, G.; Nicoletti, I.; Martelli, M. P.; Klein-Hitpaß, Ludger; Falini, B.; Tiacci, E.
    The BRAF-MEK-ERK pathway in hairy cell leukemia : a comprehensive dissection in primary leukemic cells of its biological and therapeutic relevance
    In: Haematologica Jg. 99 (2014) Nr. Suppl. 1, S. 502
    ISSN: 0390-6078; 1592-8721
  • Naschberger, Elisabeth; Schellerer, VeraS; Schaal, Ute; Grenz, Sandra; Liebl, Andrea; Jenzer, Maximilian; Britzen-Laurent, Nathalie; Ekici, ArifB; Klein-Hitpaß, Ludger; Keck, Bastian; Wach, Sven; Rau, TilmanT; Merkel, Susanne; Croner, RolandS; Hohenberger, Werner; Stuerzi, Michael
    Tumor microenvironment-dependent heterogeneity and cytogenetic abnormality of tumor endothelial cells in human colorectal carcinoma
    In: Journal of Clinical Oncology Jg. 32 (2014) Nr. 15 Suppl., S. e22012
    ISSN: 0732-183X; 1527-7755
  • Schlegelmilch, Katrin; Keller, Alexander; Zehe, Viola; Hondke, Sylvia; Schilling, Tatjana; Jakob, Franz; Klein-Hitpaß, Ludger; Schütze, Norbert
    WISP 1 is an important survival factor in human mesenchymal stromal cells
    In: Gene Jg. 551 (2014) Nr. 2, S. 243 - 254
    ISSN: 0378-1119
  • Baars, Theodor; Skyschally, Andreas; Klein-Hitpaß, Ludger; Cario, Elke; Erbel, Raimund; Heusch, Gerd; Kleinbongard, Petra
    microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigs
    In: Pflügers Archiv : European Journal of Physiology Jg. 466 (2014) Nr. 10, S. 1953 - 1961
    ISSN: 1432-2013
  • Wieczorek, Dagmar; Bögershausen, Nina; Beleggia, Filippo; Steiner-Haldenstätt, Sabine; Pohl, Esther; Li, Yun; Milz, Esther; Martin, Marcel; Thiele, Holger; Altmüller, Janine; Alanay, Yasemin; Kayserili, Hülya; Klein-Hitpaß, Ludger; Böhringer, Stefan; Wollstein, Andreas; Albrecht, Beate; Boduroglu, Koray; Caliebe, Almuth; Chrzanowska, Krystyna; Cogulu, Ozgur; Cristofoli, Francesca; Czeschik, Johanna Christina; Devriendt, Koenraad; Dotti, Maria Teresa; Elcioglu, Nursel; Gener, Blanca; Goecke, Timm O.; Krajewska-Walasek, Małgorzata; Guillén-Navarro, Encarnación; Hayek, Joussef; Houge, Gunnar; Kilic, Esra; Simsek-Kiper, Pelin Özlem; López-González, Vanesa; Küchler, Alma; Lyonnet, Stanislas; Mari, Francesca; Marozza, Annabella; Dramard, Michèle Mathieu; Mikat, Barbara; Morin, Gilles; Morice-Picard, Fanny; Özkinay, Ferda; Rauch, Anita; Renieri, Alessandra; Tinschert, Sigrid; Eda Utine, G.; Vilain, Catheline; Vivarelli, Rossella; Zweier, Christiane; Nürnberg, Peter; Rahmann, Sven; Vermeesch, Joris; Lüdecke, Hermann-Josef; Zeschnigk, Michael; Wollnik, Bernd
    A comprehensive molecular study on Coffin–Siris and Nicolaides–Baraitser syndromes identifies abroad molecular and clinical spectrum converging on altered chromatin remodelingremodeling
    In: Human Molecular Genetics Jg. 22 (2013) Nr. 25, S. 5121 - 5135
    ISSN: 1460-2083; 0964-6906
  • Matschke, Johannes; Riffkin, H.; Handrick, R.; Klein-Hitpaß, Ludger; Jendrossek, Verena
    Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell death
    In: European Journal of Cancer Jg. 49 (2013) Nr. Suppl. 2, S. 101
    ISSN: 0959-8049
  • Czeschik, Christina; Voigt, C.; Alanay, Y.; Albrecht, Beate; Avci, S.; Fitzpatrick, D.; Goudie, D.R.; Hehr, U.; Hoogeboom, A.J.; Kayserili, H.; Simsek-Kiper, P.O.; Klein-Hitpaß, Ludger; Küchler, Alma; López-González, V.; Martin, M.; Rahmann, Sven; Schweiger, Bernd; Splitt, M.; Wollnik, B.; Lüdecke, Hermann-Josef; Zeschnigk, Michael; Wieczorek, Dagmar
    Clinical and mutation data in 12 patients with the clinical diagnosis of Nager syndrome
    In: Human Genetics Jg. 132 (2013) Nr. 8, S. 885 - 898
    ISSN: 0340-6717; 1432-1203
  • Kehrmann, Angela; Truong, Ha; Repenning, Antje; Boger, Regina; Klein-Hitpaß, Ludger; Pascheberg, Ulrich; Beckmann, Alf; Opalka, Bertram; Kleine-Lowinski, Kerstin
    Complementation of non-tumorigenicity of HPV18-positive cervical carcinoma cells involves differential mRNA expression of cellular genes including potential tumor suppressor genes on chromosome 11q13
    In: Cancer Genetics Jg. 206 (2013) Nr. 7-8, S. 279 - 292
    ISSN: 2210-7762
  • Karlisch, Carmen; Harati, Kamran; Chromik, Ansgar Michael; Bulut, Daniel; Klein-Hitpaß, Ludger; Goertz, Ole; Hirsch, Tobias; Lehnhardt, Marcus; Uhl, Waldemar H.; Daigeler, Adrien
    Effects of TRAIL and taurolidine on apoptosis and proliferation in human rhabdomyosarcoma, leiomyosarcoma and epithelioid cell sarcoma
    In: International Journal of Oncology Jg. 42 (2013) Nr. 3, S. 945 - 956
    ISSN: 1791-2423
  • Martin, Marcel; Maßhöfer, Lars; Temming, Petra; Rahmann, Sven; Metz, Claudia; Bornfeld, Norbert; van de Nes, Johannes; Klein-Hitpaß, Ludger; Hinnebusch, Alan G.; Horsthemke, Bernhard; Lohmann, Dietmar; Zeschnigk, Michael
    Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
    In: Nature Genetics Jg. 45 (2013) Nr. 8, S. 933 - 936
    ISSN: 1061-4036; 1546-1718
  • Goethert, JoachimRud; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Zesewitz, Marie-Loui; Sellmann, Ludger; Röth, Alexander; Pircher, Hanspeter; Dührsen, Ulrich; Dürig, Jan
    Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1(+) effector memory phenotype
    In: Cancer Immunology, Immunotherapy Jg. 62 (2013) Nr. 11, S. 1697 - 1709
    ISSN: 0340-7004; 1432-0851
  • Berulava, Tea; Ziehe, Matthias; Klein-Hitpaß, Ludger; Mladenov, Emil; Thomale, Jürgen; Rüther, Ulrich; Horsthemke, Bernhard
    FTO levels affect RNA modification and the transcriptome
    In: European Journal of Human Genetics Jg. 21 (2013) Nr. 3, S. 317 - 323
    ISSN: 1018-4813; 1476-5438
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, R.; Seifert, Marc; Jäger, Ursula; Tschurtschenthaler, G.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 196
    ISSN: 0378-584X; 1423-0240
  • Göbel, Maria; Eisele, Lewin; Möllmann, Michael; Hüttmann, Andreas; Johansson, Patricia; Scholtysik, Rene; Bergmann, Manuela; Busch, Raymonde; Döhner, Hartmut; Hallek, Michael; Seiler, Till; Stilgenbauer, Stephan; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan
    Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic Leukemia
    In: PLoS One Jg. 23 (2013) Nr. 8, S. e72107
    ISSN: 1932-6203
  • Lutzny, Gloria; Kocher, Thomas; Schmidt-Supprian, Marc; Rudelius, Martina; Klein-Hitpaß, Ludger; Finch, Andrew J; Dürig, Jan; Wagner, Michaela; Haferlach, Claudia; Kohlmann, Alexander; Schnittger, Susanne; Seifert, Marc; Wanninger, Stefan; Zaborsky, Nadja; Oostendorp, Robert; Ruland, Jürgen; Leitges, Michael; Kuhnt, Toni; Schäfer, Yvonne; Lampl, Benedikt; Peschel, Christian; Egle, Alexander; Ringshausen, Ingo
    Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo
    In: Cancer Cell Jg. 23 (2013) Nr. 1, S. 77 - 92
    ISSN: 1535-6108
  • Kohler, Julia; Popov, Cvetan; Klotz, Barbara; Alberton, Paolo; Prall, Wolf Christian; Haasters, Florian; Müller-Deubert, Sigrid; Ebert, Regina; Klein-Hitpaß, Ludger; Jakob, Franz; Schieker, Matthias; Docheva, Denitsa
    Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration
    In: Aging Cell Jg. 12 (2013) Nr. 6, S. 988 - 999
    ISSN: 1474-9718; 1474-9726
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, René; Seifert, Marc; Jäger, Ulrich; Tschurtschenthaler, Gertraud; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Blood Jg. 120 (2012) Nr. 21, S. 3512
    ISSN: 0006-4971; 1528-0020
  • Hanoun, Maher; Eisele, Lewin; Suzuki, Masako; Greally, John M.; Hüttmann, Andreas; Aydin, Semra; Scholtysik, René; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan
    Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic Leukemia
    In: PLoS One Jg. 7 (2012) Nr. 12, S. e34347
    ISSN: 1932-6203
  • Heise, Franziska; Chung, Ho-Ryun; Weber, Jan; Xu, Zhenyu; Klein-Hitpaß, Ludger; Steinmetz, Lars M.; Vingron, Martin; Ehrenhofer-Murray, Ann
    Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange
    In: Nucleic Acids Research Jg. 40 (2012) Nr. 1, S. 65 - 74
    ISSN: 1362-4962; 0301-5610; 0305-1048
  • Ebert, Regina; Zeck, Sabine; Meissner-Weigl, Jutta; Klotz, Barbara; Rachner, Tilman D.; Benad, Peggy; Klein-Hitpaß, Ludger; Rudert, Maximilian; Hofbauer, Lorenz C.; Jakob, Franz
    Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells
    In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 50 (2012) Nr. 3, S. 723 - 732
    ISSN: 1873-2763; 8756-3282
  • Molenaar, Jan J.; Domingo-Fernández, Raquel; Ebus, Marli E.; Lindner, Sven; Koster, Jan; Drabek, Ksenija; Mestdagh, Pieter; Van Sluis, Peter; Valentijn, Linda J.; Van Nes, Johan; Broekmans, Marloes; Haneveld, Franciska; Volckmann, Richard; Bray, Isabella; Heukamp, Lukas; Sprüssel, Annika; Thor, Theresa; Kieckbusch, Kristina; Klein-Hitpaß, Ludger; Fischer, Matthias; Vandesompele, Jo; Schramm, Alexander; Van Noesel, Max M.; Varesio, Luigi; Speleman, Frank; Eggert, Angelika; Stallings, Raymond L.; Caron, Huib N.; Versteeg, Rogier; Schulte, Johannes
    LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
    In: Nature Genetics Jg. 44 (2012) Nr. 11, S. 1199 - 1206
    ISSN: 1061-4036; 1546-1718
  • Gobel, M.; Eisele, Lewin; Hüttmann, Andreas; Bergmann, M.; Busch, R.; Stilgenbauer, S.; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan
    Progranulin plasma concentration is a novel independent prognostic marker in chronic lymphocytic leukemia
    In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 100
    ISSN: 0378-584X; 1423-0240
  • Lutzny, G.; Kocher, T.; Rudelius, M.; Schmidt-Supprian, M.; Klein-Hitpaß, Ludger; Dürig, Jan; Oostendorp, RAJ; Peschel, C.; Egle, A.; Ringshausen, I.
    Protein Kinase C-beta Dependent Activation of NF-kappa B in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B-Cells in Vivo
    In: Blood Jg. 120 (2012) Nr. 21, S. 314
    ISSN: 0006-4971; 1528-0020
  • Sellmann, Ludger; Scholtysik, R.; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Röth, Alexander
    Significance of chromosomal aberrations and HMGA2 expression in Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 220 - 221
    ISSN: 0378-584X; 1423-0240
  • Harati, Kamran; Chromik, Ansgar Michael; Bulut, D.; Goertz, O.; Hahn, Stephan; Hirsch, Tobias; Klein-Hitpaß, Ludger; Lehnhardt, Marcus; Uhl, Waldemar; Daigeler, Adrien
    TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in HT1080 human fibrosarcoma cells
    In: Anticancer Research Jg. 32 (2012) Nr. 7, S. 2967 - 2984
    ISSN: 0250-7005; 1791-7530
  • Benisch, Peggy; Schilling, Tatjana; Klein-Hitpaß, Ludger; Frey, Sönke P.; Seefried, Lothar; Raaijmakers, Nadja; Krug, Melanie; Regensburger, Martina; Zeck, Sabine; Schinke, Thorsten; Amling, Michael; Ebert, Regina; Jakob, Franz
    The Transcriptional Profile of Mesenchymal Stem Cell Populations in Primary Osteoporosis Is Distinct and Shows Overexpression of Osteogenic Inhibitors
    In: PLoS One Jg. 7 (2012) Nr. 9, S. e45142
    ISSN: 1932-6203
  • Wirsing, Andrea; Senkel, Sabine; Klein-Hitpaß, Ludger; Ryffel, Gerhart U.
    A Systematic Analysis of the 3′UTR of HNF4A mRNA Reveals an Interplay of Regulatory Elements Including miRNA Target Sites
    In: PLoS One Jg. 6 (2011) Nr. 11, S. 0027438
    ISSN: 1932-6203
  • Mitter, Diana; Ullmann, Reinhard; Muradyan, Artur; Klein-Hitpaß, Ludger; Kanber, Deniz; Õunap, Katrin; Kaulisch, Marc; Lohmann, Dietmar
    Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions
    In: European Journal of Human Genetics Jg. 19 (2011) Nr. 9, S. 947 - 958
    ISSN: 1018-4813
  • Schwerk, Christian; Adam, Rüdiger; Borkowski, Julia; Schneider, Henriette; Klenk, Michael; Zink, Sascha; Quednau, Natascha; Schmidt, Nicole; Stump, Carolin; Sagar, Anubha; Spellerberg, Barbara; Tenenbaum, Tobias; Koczan, Dirk; Klein-Hitpaß, Ludger; Schroten, Horst
    In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis : release of pro-inflammatory cytokines and chemokines
    In: Microbes and Infection Jg. 13 (2011) Nr. 11, S. 953 - 962
    ISSN: 1286-4579; 1769-714X
  • Gustmann, S.; Klein-Hitpaß, Ludger; Stephan, Harald; Weber, Susanne; Bornfeld, Norbert; Kaulisch, Marc; Lohmann, Dietmar; Dünker, Nicole
    Loss at chromosome arm 16q in retinoblastoma : confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted region
    In: Genes, Chromosomes and Cancer Jg. 50 (2011) Nr. 5, S. 327 - 337
    ISSN: 1045-2257; 1098-2264
  • Saba, Ingrid; Kosan, Christian; Vassen, Lothar; Klein-Hitpaß, Ludger; Möröy, Tarik
    Miz-1 is required to coordinate the expression of TCRβ and p53 effector genes at the pre-TCR "β-selection" checkpoint
    In: The Journal of Immunology Jg. 187 (2011) Nr. 6, S. 2982 - 2992
    ISSN: 1550-6606
  • Dürig, Jan; Dührsen, Ulrich; Klein-Hitpaß, Ludger; Worm, J.; Rode Hansen, J.B.; Wissenbach, M.
    The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia
    In: Leukemia Jg. 25 (2011) Nr. 4, S. 638 - 647
    ISSN: 0887-6924; 1476-5551
  • Caliebe, Almuth; Vater, I.; Plendl, Hansjörg; Gesk, Stefan; Siebert, Reiner; Cremer, F. W.; Klein-Hitpaß, Ludger
    A 439 kb-sized homozygous deletion in 17p13.3 leading to biallelic loss of the ASPA as cause of Canavan disease detected by SNP-array analysis : Letter to the Editor
    In: Molecular Genetics and Metabolism Jg. 99 (2010) Nr. 2, S. 184 - 185
    ISSN: 1096-7192; 1096-7206
  • Kosubek, Anna; Klein-Hitpaß, Ludger; Rademacher, Katrin; Horsthemke, Bernhard; Ryffel, Gerhart U.
    Aging of Xenopus tropicalis Eggs Leads to Deadenylation of a Specific Set of Maternal mRNAs and Loss of Developmental Potential
    In: PLoS One Jg. 5 (2010) Nr. 10, S. e13532
    ISSN: 1932-6203
  • Limbert, Catarina; Ebert, Regina; Schilling, Tatjana; Path, Gunter; Benisch, Peggy; Klein-Hitpaß, Ludger; Seufert, Jochen; Jakob, Franz
    Functional signature of human islet-derived precursor cells compared to bone marrow-derived mesenchymal stem cells
    In: Stem Cells and Development Jg. 19 (2010) Nr. 5, S. 679 - 691
    ISSN: 1547-3287
  • Sellmann, Ludger; Scholtysik, Rene; Kreuz, Markus; Cyrull, Sandra; Tiacci, Enrico; Stanelle, Jens; Carpinteiro, Alexander; Nückel, Holger; Boes, Tanja; Gesk, Stefan; Siebert, Reiner; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan; Küppers, Ralf
    Gene dosage effects in chronic lymphocytic leukemia
    In: Cancer Genetics and Cytogenetics Jg. 203 (2010) Nr. 2, S. 149 - 160
    ISSN: 1873-4456
  • Lanckohr, C.; Kasprzynski, Alice; Klein-Hitpaß, Ludger; Homann, Heinz Herbert; Lehnhardt, Marcus; Müller, Oliver; Kuhnen, Cornelius; Herter, Peter
    Identifikation überexprimierter Gene in myxoid-rundzelligen Liposarkomen : DNA-Mikroarray-Analyse und immunhistochemische Korrelation
    In: Der Pathologe Jg. 31 (2010) Nr. 1, S. 60 - 66
    ISSN: 1432-1963
  • Adrien, Daigeler; Klein-Hitpaß, Ludger; Ingo, Stricker; Müller, Oliver Priv.-Doz. Dr. med.; Cornelius, Kuhnen; Michael, Chromik Ansgar; Lars, Steinstraesser; Ole, Goertz; Hans-Ulrich, Steinau; Marcus, Lehnhardt
    Malignant fibrous histiocytoma-pleomorphic sarcoma, NOS gene expression, histology, and clinical course : A pilot study
    In: Langenbeck's Archives of Surgery Jg. 395 (2010) Nr. 3, S. 261 - 275
    ISSN: 1435-2451; 1435-2443
  • Johansson, Patricia; Eisele, Lewin; Klein-Hitpaß, Ludger; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan; Nückel, Holger
    Percentage of smudge cells determined on routine blood smears is a novel prognostic factor in chronic lymphocytic leukemia
    In: Leukemia Research Jg. 34 (2010) Nr. 7, S. 892 - 898
    ISSN: 1873-5835
  • Daigeler, Adrien; Chromik, Ansgar M.; Haendschke, Kathrin; Emmelmann, Sabine; Siepmann, Monica; Hensel, Karin; Schmitz, Georg; Klein-Hitpaß, Ludger; Steinau, Hans U.; Lehnhardt, Marcus; Hauser, Joerg
    Synergistic effects of sonoporation and taurolidin/TRAIL on apoptosis in human fibrosarcoma
    In: Ultrasound in Medicine and Biology Jg. 36 (2010) Nr. 11, S. 1893 - 1906
    ISSN: 1879-291X; 0301-5629
  • Schirling, Corinna; Heseding, Christiane; Heise, Franziska; Kesper, Dörthe; Klebes, Ansgar; Klein-Hitpaß, Ludger; Vortkamp, Andrea; Hoffmann, Daniel; Saumweber, Harald; Ehrenhofer-Murray, Ann
    Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60
    In: Chromosoma Jg. 119 (2010) Nr. 1, S. 99 - 113
    ISSN: 0009-5915; 1432-0886
  • Eisele, Lewin; Prinz, Robert; Klein-Hitpaß, Ludger; Nückel, Holger; Lowinksi, Kerstin; Thomale, Jürgen; Möller, Lars; Dührsen, Ulrich; Dürig, Jan
    Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia
    In: European Journal of Haematology Jg. 83 (2009) Nr. 4, S. 320 - 327
    ISSN: 1600-0609
  • Schulte, Johannes H.; Lim, Soyoung; Schramm, Alexander; Friedrichs, Nicolaus; Koster, Jan; Versteeg, Rogier; Ora, Ingrid; Pajtler, Kristian; Klein-Hitpaß, Ludger; Kuhfittig-Kulle, Steffi; Metzger, Eric; Schüle, Roland; Eggert, Angelika; Buettner, Reinhard; Kirfel, Jutta
    Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : implications for therapy
    In: Cancer Research Jg. 69 (2009) Nr. 5, S. 2065 - 2071
    ISSN: 0008-5472; 1538-7445; 0099-7013; 0099-7374
  • Bug, Stefanie; Dürig, Jan; Oyen, Florian; Klein-Hitpaß, Ludger; Martin-Subero, Jose; Harder, Lana; Baudis, Michael; Arnold, Norbert; Kordes, Uwe; Dührsen, Ulrich; Schneppenheim, Reinhard; Siebert, Reiner
    Recurrent loss, but lack of mutations, of the SMARCB1 tumor suppressor gene in T-cell prolymphocytic leukemia with TCL1A–TCRAD juxtaposition
    In: Cancer Genetics and Cytogenetics Jg. 192 (2009) Nr. 1, S. 44 - 47
    ISSN: 1873-4456
  • Edelmann, J.; Klein-Hitpaß, Ludger; Führer, A.; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells
    In: Leukemia Research Jg. 32 (2008) Nr. 10, S. 1565 - 1572
    ISSN: 1873-5835
  • Schulte, Johannes; Kuhfittig-Kulle, Steffi; Klein-Hitpaß, Ludger; Schramm, Alexander; Biard, Denis S. F.; Pfeiffer, Petra; Eggert, Angelika
    Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cells
    In: DNA Repair Jg. 7 (2008) Nr. 10, S. 1757 - 1764
    ISSN: 1568-7864; 1568-7856
  • Schulte, Johannes; Horn, Sebastian; Otto, Tobias; Samans, Birgit; Heukamp, Lukas C; Eilers, Ursula-Christa; Krause, Michael; Astrahantseff, Kathy; Klein-Hitpaß, Ludger; Buettner, Reinhard; Schramm, Alexander; Christiansen, Holger; Eilers, Martin; Eggert, Angelika; Berwanger, Bernd
    MYCN regulates oncogenic MicroRNAs in neuroblastoma
    In: International Journal of Cancer Jg. 122 (2008) Nr. 3, S. 699 - 704
    ISSN: 0020-7136; 1097-0215
  • Dürig, Jan; Bug, S.; Klein-Hitpaß, Ludger; Boes, Tanja; Jöns, T.; Harder, L.; Baudis, M.; Dührsen, Ulrich; Siebert, Reiner
    Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q11q32)
    In: Leukemia Jg. 21 (2007) Nr. 10, S. 2153 - 2163
    ISSN: 0887-6924; 1476-5551
  • Kuhfittig-Kulle, Steffi; Schulte, J. H.; Mahlow, E.; Klein-Hitpaß, Ludger; Schramm, Alexander; Pfeiffer, P.; Eggert, A.
    Neurotrophin receptor status influences the capacity of nonhomologous DNA end joining INSY5Y neuroblastoma cells
    In: Klinische Pädiatrie Jg. 219 (2007) Nr. 3, S. 187 - 187
    ISSN: 0300-8630; 1439-3824
  • Knauer, Shirley; Krämer, Oliver H.; Knösel, Thomas; Engels, Knut; Rödel, Franz; Kovács, Adorján F.; Dietmaier, Wolfgang; Klein-Hitpaß, Ludger; Habtemichael, Negusse; Schweitzer, Andrea; Brieger, Jürgen; Rödel, Claus; Mann, Wolf; Petersen, Iver; Heinzel, Thorsten; Stauber, Roland H.
    Nuclear export is essential for the tumor-promoting activity of survivin
    In: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 / Jg. 21 (2007) Nr. 1, S. 207 - 216
    ISSN: 0892-6638; 0892-6638
  • Knauer, Shirley; Bier, Carolin; Schlag, Peter; Fritzmann, Johannes; Dietmaier, Wolfgang; Rödel, Franz; Klein-Hitpass, Ludger; Kovács, Adoriàn F.; Döring, Claudia; Hansmann, Martin-Leo; Hofmann, Wolf-Karsten; Kunkel, Martin; Brochhausen, Christoph; Engels, Knut; Lippert, Burkhard M.; Mann, Wolf; Stauber, Roland H.
    The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex protein
    In: Cell Cycle Jg. 6 (2007) Nr. 12, S. 1502 - 1509
    ISSN: 1538-4101; 1554-8627
  • Hüttmann, Andreas; Klein-Hitpaß, Ludger; Thomale, Jürgen; Deenen, R.; Nückel, Holger; Ebeling, Peter; Führer, A.; Edelmann, J.; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status
    In: Leukemia Jg. 20 (2006) Nr. 10, S. 1774 - 1782
    ISSN: 0887-6924; 1476-5551
  • Nückel, Holger; Hüttmann, Andreas; Klein-Hitpaß, Ludger; Schroers, Roland; Führer, Anja; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Lipoprotein lipase expression is a novel prognostic factor in B-cell chronic lymphocytic leukemia
    In: Leukemia & Lymphoma Jg. 47 (2006) Nr. 6, S. 1053 - 1061
    ISSN: 1029-2403
  • Schulte, Johannes; Schramm, Alexander; Samans, B.; Krause, M.; Horn, S.; Fagin, A.; Astrahantseff, K.; Klein-Hitpaß, Ludger; Witt, O.; Westermann, F.; Christiansen, H.; Eilers, M.; Berwanger, B.; Eggert, Angelika
    MicroRNA expression analysis in neuroblastoma using pligonuclectide arrays
    In: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 194
    ISSN: 0300-8630; 1439-3824
  • Pressel, T.; Schramm, Alexander; Schulte, Johannes; Klein-Hitpaß, Ludger; Eggert, Angelika
    Microarray analysis defines IPL/TSSC3 as a potential target mediating the synergistic effects of combined thermo-chemotherapy in neuroblastoma cells
    In: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 192 - 193
    ISSN: 0300-8630; 1439-3824
  • Schroers, R.; Griesinger, F.; Trümper, L.; Haase, D.; Kulle, B.; Klein-Hitpaß, Ludger; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia
    In: Leukemia Jg. 19 (2005) Nr. 5, S. 750 - 758
    ISSN: 0887-6924; 1476-5551
  • Grasemann, Corinna; Gratias, S.; Stephan, H.; Schüler, A.; Schramm, Alexander; Klein-Hitpaß, Ludger; Rieder, H.; Schneider, S.; Kappes, F.; Eggert, A.; Lohmann, Dietmar
    Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma
    In: Oncogene Jg. 24 (2005) Nr. 42, S. 6441 - 6449
    ISSN: 0950-9232; 1476-5594
  • Schulte, Johannes; Schramm, Alexander; Klein-Hitpaß, Ludger; Klenk, M.; Wessels, H.; Hauffa, Berthold; Eils, J.; Eils, R.; Brodeur, G. M.; Schweigerer, L.; Havers, Werner; Eggert, A.
    Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas
    In: Oncogene Jg. 24 (2005) Nr. 1, S. 165 - 177
    ISSN: 0950-9232; 1476-5594
  • Schramm, Alexander; Schulte, Johannes; Klein-Hitpaß, Ludger; Havers, Werner; Sieverts, H.; Berwanger, B.; Christiansen, H.; Warnat, P.; Brors, B.; Eils, J.; Eils, R.; Eggert, A.
    Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling
    In: Oncogene Jg. 24 (2005) Nr. 53, S. 7902 - 7912
    ISSN: 0950-9232; 1476-5594
  • Dürig, Jan; Nückel, Holger; Hüttmann, Andreas; Kruse, Elisabeth; Hölter, Tanja; Halfmeyer, Katja; Führer, Anja; Rudolph, Roland; Kalhori, Nasa; Nusch, Arnd; Deaglio, Silvia; Malavasi, Fabio; Möröy, Tarik; Klein-Hitpaß, Ludger; Dührsen, Ulrich
    Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia
    In: Blood Jg. 101 (2003) Nr. 7, S. 2748 - 2755
    ISSN: 0006-4971; 1528-0020
  • Schulte, Johannes; Schramm, Alexander; Pressel, T.; Klein-Hitpaß, Ludger; Kremens, Bernhard; Eils, J.; Havers, Werner; Eggert, Angelika
    Microarray-analysis : a new approach to study the molecular mechanisms of thermo-chemotherapy
    In: Klinische Pädiatrie Jg. 215 (2003) Nr. 6, S. 298 - 302
    ISSN: 0300-8630; 1439-3824
  • Dürig, Jan; Nückel, Holger; Cremer, M.; Führer, A.; Halfmeyer, K.; Fandrey, Joachim; Möröy, Tarik; Klein-Hitpaß, Ludger; Dührsen, Ulrich
    ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia
    In: Leukemia Jg. 17 (2003) Nr. 12, S. 2426 - 2434
    ISSN: 0887-6924; 1476-5551
  • Klein-Hitpaß, Ludger; Möröy, Tarik
    Der Biochip : Neue Horizonte in Prävention, Diagnose und Nachsorge von Tumorerkrankungen
    In: Essener Unikate: Berichte aus Forschung und Lehre (2001) Nr. 15 : Klinische Onkologie – Fortschritte in der Behandlung von Krebserkrankungen, S. 12 - 19
    ISSN: 1869-3881
  • Abstracts

  • Chen, Yiyang; Zaun, Yasmin; Arnold, Lucas; Weissenfels, Kerstin; Schmid, Kurt Werner; Klein-Hitpaß, Ludger; Squire, Anthony; Bertram, Stefanie; Duehrsen, Ulrich; Hanoun, Maher;
    Acute Myeloid Leukemia Induced Remodelling of the Human Bone Marrow Niche Predicts Clinical Outcome
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood Jg. 132 (2018) Nr. Supplement 1, S. 3851 - 3851
    ISSN: 1528-0020; 0006-4971
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Bergmann, A.; Siebert, R.; Scholtysik, R.; Przekopowitz, M.; Seifert, M.; Zenz, T.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Genomic profiling of T-cell Prolymphocytic Leukemia (T-PLL) identifies novel recurrent mutations in SAMHD1 and PTPRC
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3: Jahrestagung der ­Deutschen, Österreichischen und ­Schweizerischen ­Gesellschaften für Hämatologie und ­Medizinische Onkologie, Leipzig, 14.–18. Oktober 2016: Abstracts, S. 238 - 238
    ISSN: 2296-5270
  • Lollies, A.; Hartmann, S.; Schneider, M.; Bracht, T.; Arnolds, Judith; Klein-Hitpaß, Ludger; Sitek, B.; Hansmann, M. L.; Küppers, Ralf; Weniger, Marc
    The AP-1 transcription factor BATF3 regulates MYC expression and is required for tumor cell survival in classical Hodgkin lymphoma and anaplastic large cell lymphoma
    In: Haematologica Jg. 101 (2016) Nr. S 5: You have access 10th International Symposium on Hodgkin Lymphoma, Cologne, Germany, October 22–25, 2016, Abstract Book, S. 2
    ISSN: 0390-6078; 1592-8721
  • Stuschke, Martin; Sak, Ali; Abu Jawad, Jehad; Bachmann, H. S.; Tinhofer, I.; Budach, V.; Baumann, M.; Krause, M.; Lohaus, F.; Linge, A.; Gkika, E.; Balermpas, P.; Roedel, C.; Avlar, M.; Grosu, A. L.; Abdollahi, A.; Debus, J.; Bayer, C.; Belka, C.; Pigorsch, S.; Combs, S. E.; Moennich, D.; Zips, D.; Lang, Stephan; Klein-Hitpaß, Ludger;
    Einzelnukleotid Polymorphismen in Reparaturproteinen sind prognoserelevant für des Überleben von Kopf-Hals- Tumorpatienten nach postoperativer Radiochemotherapie mit Cisplatin (DKTK-ROG)
    21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,
    In: Strahlentherapie und Onkologie Jg. 191 (2015) Nr. Suppl. 1,
    ISSN: 0179-7158; 1439-099X
  • Benisch, P.; Frey, S.; Seefried, Lothar; Klein-Hitpaß, Ludger; Ebert, R.; Jakob, F.;
    The transcriptome of hMSC from osteoporotic donors is distinct from hMSC of 80+ donors
    ECTS 2012, 39th Annual Congress; 19-23 May 2012; Stockholm, Sweden,
    In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 50 (2012) Nr. Suppl. 1, S. S83
    ISSN: 1873-2763; 8756-3282
  • Ebert, R.; Meissner-Weigl, J.; Zeck, S.; Klein-Hitpaß, Ludger; Rachner, T.; Benad, P.; Hofbauer, L.; Jakob, F.
    Modulation of Proliferation in MCF7 Cells by Regulated Expression of KLF2, 4, 6 and Ki-67 After Treatment With Zoledronic Acid
    In: European Journal of Cancer Jg. 47 (2011) Nr. Suppl. 1, S. 359
    ISSN: 0959-8049
  • Göbel, M.; Eisele, Lewin; Huttmann, A.; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan;
    Progranulin plasma levels predict time to first treatment and overall survival in chronic lymphocytic leukemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 196 - 196
    ISSN: 0378-584X; 1423-0240; 2296-5262; 2296-5270
  • Beiträge in Sammelwerken und Tagungsbänden

  • Leitão, Elsa; Beygo, Jasmin; Zeschnigk, Michael; Klein-Hitpaß, Ludger; Bargull, Marcel; Rahmann, Sven; Horsthemke, Bernhard
    Locus-specific DNA methylation analysis by targeted deep bisulfite sequencing
    In: Epigenome Editing: Methods and Protocols 2018, S. 351 - 366
    ISBN: 978-1-4939-7773-4; 978-1-4939-7774-1