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apl. Professor/in und Privatdozent/in, Institut für Zellbiologie (Tumorforschung)
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WiSe 2024
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Laborpraktikum I für Masterstudenten der medizinischen Biologie (WP)
- Laborpraktikum II für Masterstudenten der medizinischen Biologie (WP)
- Laborpraktikum III für Masterstudenten der medizinischen Biologie (WP)
- Mitarbeiterseminar zur Besprechung aktueller Arbeiten
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
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SoSe 2024
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast CellsIn: Radiation Research , Jg. 203 2025, Nr. 1, S. 37 – 52
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Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infectionIn: Frontiers in Immunology , Jg. 14 2023, 1227191DOI, Online Volltext (Open Access)
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Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancingIn: Brain, Behavior and Immunity , Jg. 100 2022, S. 134 – 144DOI (Open Access)
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Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain InjuryIn: Stroke , Jg. 53 2022, Nr. 2, S. 381 – 390DOI (Open Access)
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TLR2-induced CD8⁺ T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsisIn: Frontiers in Immunology , Jg. 13 2022, 945409DOI (Open Access)
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A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of HypoxiaIn: Frontiers in Cellular and Infection Microbiology , Jg. 11 2021, 639620DOI (Open Access)
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Acute myeloid leukemia–induced remodeling of the human bone marrow niche predicts clinical outcomeIn: Blood Advances , Jg. 4 2020, Nr. 20, S. 5257 – 5268DOI (Open Access)
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Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemiaIn: Therapeutic Advances in Hematology , Jg. 11 2020, S. 1 – 15DOI, Online Volltext (Open Access)
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Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiomeIn: Immunology , Jg. 159 2020, Nr. 3, S. 344 – 353DOI (Open Access)
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Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencingIn: Cancers , Jg. 12 2020, Nr. 4, 986DOI, Online Volltext (Open Access)
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Mutations in PIGA cause a CD52-/GPI-anchor-deficient phenotype complicating alemtuzumab treatment in T-cell prolymphocytic leukemiaIn: European Journal of Haematology , Jg. 105 2020, Nr. 6, S. 786 – 796DOI (Open Access)
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Targeted bisulfite sequencing : A novel tool for the assessment of DNA methylation with high sensitivity and increased coverageIn: Psychoneuroendocrinology , Jg. 120 2020, 104784DOI (Open Access)
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Genome-wide analysis of the nucleosome landscape in individuals with coffin-siris syndromeIn: Cytogenetics and Cell Genetics , Jg. 159 2019, S. 1 – 11DOI (Open Access)
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Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases (JID) , Jg. 219 2019, Nr. 3, S. 497 – 508DOI (Open Access)
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Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohortIn: Acta Neuropathologica Communications , Jg. 7 2019, Nr. 1, 181DOI (Open Access)
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An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphomaIn: Leukemia , Jg. 32 2018, Nr. 1, S. 92 – 101
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Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood , Jg. 131 2018, Nr. 5, S. 546 – 557DOI (Open Access)
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Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemiaIn: Nature Communications , Jg. 9 2018, 3839DOI (Open Access)
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SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemiaIn: Blood Cancer Journal , Jg. 8 2018, Nr. 1, 11DOI (Open Access)
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A novel physiological role for cardiac myoglobin in lipid metabolismIn: Scientific Reports , Jg. 7 2017, S. 43219DOI (Open Access)
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Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesionsIn: Nature Communications , Jg. 8 2017, 15440DOI (Open Access)
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Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7In: Gut Pathogens , Jg. 9 2017, S. 30DOI (Open Access)
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Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileusIn: Gut , Jg. 66 2017, Nr. 12, S. 2110 – 2120DOI (Open Access)
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NOTCH-signaling in the tumor microenvironment is required for canonical WNT signaling in CLL cellsIn: Leukemia and Lymphoma , Jg. 58 2017, Nr. Suppl. 1, XVII International Workshop on Chronic Lymphocytic Leukemia 2017 May 12--15, 2017, New York, S. 125 – 126
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Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivoIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 114 2017, Nr. 52, S. E11323 – E11332
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OTX2 defines a subgroup of atypical teratoid rhabdoid tumors with close relationship to choroid plexus tumorsIn: Journal of Neuropathology & Experimental Neurology (JNEN) , Jg. 76 2017, Nr. 1, S. 32 – 38DOI (Open Access)
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Regions of common inter-individual DNA methylation differences in human monocytes: Genetic basis and potential functionIn: Epigenetics and Chromatin , Jg. 10 2017, Nr. 1, S. 37DOI (Open Access)
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The lung microbiome in patients with pneumocystosisIn: BMC Pulmonary Medicine , Jg. 17 2017, Nr. 1, S. 170DOI (Open Access)
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A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2AIn: The Journal of Clinical Endocrinology & Metabolism (JCEM) , Jg. 101 2016, Nr. 3, S. 1016 – 1022DOI (Open Access)
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Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cellsIn: OncoTarget , Jg. 7 2016, Nr. 46, S. 74415 – 74426DOI (Open Access)
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Epigenetic dynamics of monocyte-to-macrophage differentiationIn: Epigenetics and Chromatin , Jg. 9 2016, S. 33DOI (Open Access)
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GFI1 as a novel prognostic and therapeutic factor for AML/MDSIn: Leukemia , Jg. 30 2016, Nr. 6, S. 1237 – 1245
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Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinomaIn: The Journal of Clinical Investigation (JCI) , Jg. 126 2016, Nr. 11, S. 4187 – 4204
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Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemiaIn: International Journal of Cancer , Jg. 138 2016, Nr. 1, S. 121 – 124DOI (Open Access)
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Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomasIn: OncoTarget , Jg. 7 2016, Nr. 38, S. 62627 – 62639DOI (Open Access)
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Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemiaIn: Leukemia and Lymphoma , Jg. 57 2016, Nr. 3, S. 590 – 595
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A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studiesIn: Oncogene , Jg. 34 2015, Nr. 26, S. 3357 – 3368DOI (Open Access)
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Absence of telomerase reverse transcriptase promoter mutations in neuroblastomaIn: Biomedical Reports , Jg. 3 2015, Nr. 4, S. 443 – 446
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BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activityIn: Blood , Jg. 125 2015, Nr. 8, S. 1207 – 1216DOI (Open Access)
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Characterization of bursa subacromialis-derived mesenchymal stem cellsIn: Stem Cell Research & Therapy , Jg. 6 2015, S. 114DOI (Open Access)
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Endothelial cells isolated from colorectal carcinoma exhibit tumor microenvironment-dependent plasticity allowing the identification of SPARCL1 as a novel endothelial cell quiescence factorIn: Cancer Research , Jg. 75 2015, Nr. 15 Suppl., S. 2375
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Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 ExpressionIn: PLoS ONE , Jg. 10 2015, Nr. 9, S. e0137043DOI (Open Access)
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Functional abnormalities and changes in gene expression in fibroblasts and macrophages from the bone marrow of patients with acute myeloid leukemiaIn: International Journal of Hematology , Jg. 102 2015, Nr. 3, S. 278 – 288
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High-Resolution Genomic Analysis Does Not Qualify Atypical Plexus Papilloma as a Separate Entity Among Choroid Plexus TumorsIn: Journal of Neuropathology & Experimental Neurology (JNEN) , Jg. 74 2015, Nr. 2, S. 110 – 120DOI (Open Access)
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Interference of peritoneal dialysis fluids with cell cycle mechanismsIn: Peritoneal Dialysis International , Jg. 35 2015, Nr. 3, S. 259 – 274DOI (Open Access)
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Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell lineIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) , Jg. 79 2015, S. 150 – 161
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Pro-apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cellsIn: International Journal of Oncology , Jg. 46 2015, Nr. 4, S. 1629 – 1636DOI (Open Access)
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Resveratrol induces apoptosis and alters gene expression in human fibrosarcoma cellsIn: Anticancer Research , Jg. 35 2015, Nr. 2, S. 767 – 774
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Altering gene expression by aminocoumarins : The role of DNA supercoiling in Staphylococcus aureusIn: BMC Genomics , Jg. 15 2014, Nr. 1, S. 291DOI (Open Access)
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Everolimus Prevents Podocyte Injury Via Stabilizing Tubb2b And Dcdc2 ExpressionIn: Pediatric Nephrology , Jg. 29 2014, Nr. 9, S. 1674 – 1674
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Evolutionary origin and methylation status of human intronic CpG islands that are not present in mouseIn: Genome Biology and Evolution , Jg. 6 2014, Nr. 7, S. 1579 – 1588DOI (Open Access)
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Genome-wirde DNA copy number analysis of choroid plexus tumorsIn: Neuro-Oncology , Jg. 16 2014, Nr. Suppl. 1, S. 134
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High-resolution genomic analysis of choroid plexus tumors separates two genetic entities and identifies recurrent focal alterationsIn: Brain Pathology , Jg. 24 2014, Nr. Suppl. 1, S. 73 – 74
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Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in MiceIn: PLoS ONE , Jg. 9 2014, Nr. 7, S. e103250DOI (Open Access)
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Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-?B signaling pathwayIn: Acta Neuropathologica , Jg. 127 2014, Nr. 4, S. 609 – 611
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Supratentorial ependymomas of childhood carry C11orf95-rela fusions leading to activation of the NF-KB signalling pathwayIn: Neuro-Oncology , Jg. 16 2014, Nr. Suppl. 1, S. i24
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Supratentorial ependymomas of childhood carry C11orf95–RELA fusions leading to pathological activation of the NF-κB signaling pathwayIn: Acta Neuropathologica , Jg. 127 2014, Nr. 4, S. 609 – 611
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The BRAF-MEK-ERK pathway in hairy cell leukemia : a comprehensive dissection in primary leukemic cells of its biological and therapeutic relevanceIn: Haematologica / The Hematology Journal , Jg. 99 2014, Nr. Suppl. 1, S. 502(Open Access)
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Tumor microenvironment-dependent heterogeneity and cytogenetic abnormality of tumor endothelial cells in human colorectal carcinomaIn: Journal of Clinical Oncology (JCO) , Jg. 32 2014, Nr. 15 Suppl., S. e22012
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WISP 1 is an important survival factor in human mesenchymal stromal cellsIn: Gene , Jg. 551 2014, Nr. 2, S. 243 – 254
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microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigsIn: Pflügers Archiv: European Journal of Physiology , Jg. 466 2014, Nr. 10, S. 1953 – 1961
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A comprehensive molecular study on Coffin–Siris and Nicolaides–Baraitser syndromes identifies abroad molecular and clinical spectrum converging on altered chromatin remodelingremodelingIn: Human Molecular Genetics , Jg. 22 2013, Nr. 25, S. 5121 – 5135
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Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell deathIn: European Journal of Cancer (EJC) , Jg. 49 2013, Nr. Suppl. 2, S. 101
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Clinical and mutation data in 12 patients with the clinical diagnosis of Nager syndromeIn: Human Genetics , Jg. 132 2013, Nr. 8, S. 885 – 898
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Complementation of non-tumorigenicity of HPV18-positive cervical carcinoma cells involves differential mRNA expression of cellular genes including potential tumor suppressor genes on chromosome 11q13In: Cancer Genetics , Jg. 206 2013, Nr. 7-8, S. 279 – 292
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Effects of TRAIL and taurolidine on apoptosis and proliferation in human rhabdomyosarcoma, leiomyosarcoma and epithelioid cell sarcomaIn: International Journal of Oncology , Jg. 42 2013, Nr. 3, S. 945 – 956DOI (Open Access)
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Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3In: Nature Genetics , Jg. 45 2013, Nr. 8, S. 933 – 936
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Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1(+) effector memory phenotypeIn: Cancer Immunology, Immunotherapy , Jg. 62 2013, Nr. 11, S. 1697 – 1709
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FTO levels affect RNA modification and the transcriptomeIn: European Journal of Human Genetics , Jg. 21 2013, Nr. 3, S. 317 – 323
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Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)In: Onkologie , Jg. 36 2013, Nr. Suppl. 7, S. 196
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Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic LeukemiaIn: PLoS ONE , Jg. 23 2013, Nr. 8, S. e72107DOI (Open Access)
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Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivoIn: Cancer Cell , Jg. 23 2013, Nr. 1, S. 77 – 92DOI (Open Access)
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Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degenerationIn: Aging Cell , Jg. 12 2013, Nr. 6, S. 988 – 999
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Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)In: Blood , Jg. 120 2012, Nr. 21, S. 3512
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Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic LeukemiaIn: PLoS ONE , Jg. 7 2012, Nr. 12, S. e34347DOI (Open Access)
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Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchangeIn: Nucleic Acids Research , Jg. 40 2012, Nr. 1, S. 65 – 74DOI (Open Access)
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Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cellsIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) , Jg. 50 2012, Nr. 3, S. 723 – 732
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LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppressionIn: Nature Genetics , Jg. 44 2012, Nr. 11, S. 1199 – 1206
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Progranulin plasma concentration is a novel independent prognostic marker in chronic lymphocytic leukemiaIn: Onkologie , Jg. 35 2012, Nr. Suppl. 6, S. 100
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Protein Kinase C-beta Dependent Activation of NF-kappa B in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B-Cells in VivoIn: Blood , Jg. 120 2012, Nr. 21, S. 314
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Significance of chromosomal aberrations and HMGA2 expression in Paroxysmal Nocturnal Hemoglobinuria (PNH)In: Onkologie , Jg. 35 2012, Nr. Suppl. 6, S. 220 – 221
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TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in HT1080 human fibrosarcoma cellsIn: Anticancer Research , Jg. 32 2012, Nr. 7, S. 2967 – 2984
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The Transcriptional Profile of Mesenchymal Stem Cell Populations in Primary Osteoporosis Is Distinct and Shows Overexpression of Osteogenic InhibitorsIn: PLoS ONE , Jg. 7 2012, Nr. 9, S. e45142DOI (Open Access)
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A Systematic Analysis of the 3′UTR of HNF4A mRNA Reveals an Interplay of Regulatory Elements Including miRNA Target SitesIn: PLoS ONE , Jg. 6 2011, Nr. 11, S. 0027438DOI (Open Access)
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Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletionsIn: European Journal of Human Genetics , Jg. 19 2011, Nr. 9, S. 947 – 958DOI (Open Access)
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In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis : release of pro-inflammatory cytokines and chemokinesIn: Microbes and Infection , Jg. 13 2011, Nr. 11, S. 953 – 962
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Loss at chromosome arm 16q in retinoblastoma : confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted regionIn: Genes, Chromosomes and Cancer , Jg. 50 2011, Nr. 5, S. 327 – 337
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Miz-1 is required to coordinate the expression of TCRβ and p53 effector genes at the pre-TCR "β-selection" checkpointIn: The Journal of Immunology (JI) , Jg. 187 2011, Nr. 6, S. 2982 – 2992
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The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemiaIn: Leukemia , Jg. 25 2011, Nr. 4, S. 638 – 647
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A 439 kb-sized homozygous deletion in 17p13.3 leading to biallelic loss of the ASPA as cause of Canavan disease detected by SNP-array analysis : Letter to the EditorIn: Molecular Genetics and Metabolism , Jg. 99 2010, Nr. 2, S. 184 – 185
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Aging of Xenopus tropicalis Eggs Leads to Deadenylation of a Specific Set of Maternal mRNAs and Loss of Developmental PotentialIn: PLoS ONE , Jg. 5 2010, Nr. 10, S. e13532DOI, Online Volltext (Open Access)
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Erratum zu: Identifikation überexprimierter Gene in myxoid-rundzelligen Liposarkomen. DNA-Mikroarray-Analyse und immunhistochemische KorrelationIn: Der Pathologe , Jg. 31 2010, Nr. 3, S. 198
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Functional signature of human islet-derived precursor cells compared to bone marrow-derived mesenchymal stem cellsIn: Stem Cells and Development , Jg. 19 2010, Nr. 5, S. 679 – 691
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Gene dosage effects in chronic lymphocytic leukemiaIn: Cancer Genetics and Cytogenetics , Jg. 203 2010, Nr. 2, S. 149 – 160
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Identifikation überexprimierter Gene in myxoid-rundzelligen Liposarkomen : DNA-Mikroarray-Analyse und immunhistochemische KorrelationIn: Der Pathologe , Jg. 31 2010, Nr. 1, S. 60 – 65
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Malignant fibrous histiocytoma-pleomorphic sarcoma, NOS gene expression, histology, and clinical course : A pilot studyIn: Langenbeck's Archives of Surgery , Jg. 395 2010, Nr. 3, S. 261 – 275
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Percentage of smudge cells determined on routine blood smears is a novel prognostic factor in chronic lymphocytic leukemiaIn: Leukemia Research , Jg. 34 2010, Nr. 7, S. 892 – 898
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Synergistic effects of sonoporation and taurolidin/TRAIL on apoptosis in human fibrosarcomaIn: Ultrasound in Medicine and Biology , Jg. 36 2010, Nr. 11, S. 1893 – 1906
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Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60In: Chromosoma , Jg. 119 2010, Nr. 1, S. 99 – 113
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Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemiaIn: European Journal of Haematology , Jg. 83 2009, Nr. 4, S. 320 – 327
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Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : implications for therapyIn: Cancer Research , Jg. 69 2009, Nr. 5, S. 2065 – 2071DOI (Open Access)
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Recurrent loss, but lack of mutations, of the SMARCB1 tumor suppressor gene in T-cell prolymphocytic leukemia with TCL1A–TCRAD juxtapositionIn: Cancer Genetics and Cytogenetics , Jg. 192 2009, Nr. 1, S. 44 – 47
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Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cellsIn: Leukemia Research , Jg. 32 2008, Nr. 10, S. 1565 – 1572
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Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cellsIn: DNA Repair , Jg. 7 2008, Nr. 10, S. 1757 – 1764
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MYCN regulates oncogenic MicroRNAs in neuroblastomaIn: International Journal of Cancer , Jg. 122 2008, Nr. 3, S. 699 – 704
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Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q11q32)In: Leukemia , Jg. 21 2007, Nr. 10, S. 2153 – 2163
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Neurotrophin receptor status influences the capacity of nonhomologous DNA end joining INSY5Y neuroblastoma cellsIn: Klinische Pädiatrie , Jg. 219 2007, Nr. 3, S. 187 – 187
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Nuclear export is essential for the tumor-promoting activity of survivinIn: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 , Jg. 21 2007, Nr. 1, S. 207 – 216
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The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex proteinIn: Cell Cycle , Jg. 6 2007, Nr. 12, S. 1502 – 1509
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Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression statusIn: Leukemia , Jg. 20 2006, Nr. 10, S. 1774 – 1782
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Lipoprotein lipase expression is a novel prognostic factor in B-cell chronic lymphocytic leukemiaIn: Leukemia & Lymphoma , Jg. 47 2006, Nr. 6, S. 1053 – 1061
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MicroRNA expression analysis in neuroblastoma using pligonuclectide arraysIn: Klinische Pädiatrie , Jg. 218 2006, Nr. 3, S. 194
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Microarray analysis defines IPL/TSSC3 as a potential target mediating the synergistic effects of combined thermo-chemotherapy in neuroblastoma cellsIn: Klinische Pädiatrie , Jg. 218 2006, Nr. 3, S. 192 – 193
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Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemiaIn: Leukemia , Jg. 19 2005, Nr. 5, S. 750 – 758
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Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastomaIn: Oncogene , Jg. 24 2005, Nr. 42, S. 6441 – 6449
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Gene signatures of testicular seminoma with emphasis on expression of ets variant gene 4In: Cellular and Molecular Life Sciences - CMLS , Jg. 62 2005, Nr. 19-20, S. 2359 – 2368
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Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomasIn: Oncogene , Jg. 24 2005, Nr. 1, S. 165 – 177
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Prediction of clinical outcome and biological characterization of neuroblastoma by expression profilingIn: Oncogene , Jg. 24 2005, Nr. 53, S. 7902 – 7912
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Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemiaIn: Blood , Jg. 101 2003, Nr. 7, S. 2748 – 2755
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Microarray-analysis : a new approach to study the molecular mechanisms of thermo-chemotherapyIn: Klinische Pädiatrie , Jg. 215 2003, Nr. 6, S. 298 – 302
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ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemiaIn: Leukemia , Jg. 17 2003, Nr. 12, S. 2426 – 2434
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Der Biochip : Neue Horizonte in Prävention, Diagnose und Nachsorge von TumorerkrankungenIn: Essener Unikate: Berichte aus Forschung und Lehre 2001, Nr. 15 : Klinische Onkologie – Fortschritte in der Behandlung von Krebserkrankungen, S. 12 – 19Online Volltext (Open Access)
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Molecular Mechanisms in the Pathogenesis of Composite Lymphomas
4th International Symposium on Childhood, Adolescent and Young Adult Hodgkin Lymphoma, ISCAYAHL 2020, 13 - 16 May 2020, Berlin, Germany,In: Klinische Pädiatrie , Jg. 232 2020, Nr. 02, S. 80 -
Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia : Results of an in Vitro and In Vivo Analysis
61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,In: Blood , Jg. 134 2019, Nr. Supplement_1, S. 3734 – 3734DOI (Open Access) -
Acute Myeloid Leukemia Induced Remodelling of the Human Bone Marrow Niche Predicts Clinical Outcome
60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,In: Blood , Jg. 132 2018, Nr. Supplement 1, S. 3851 – 3851DOI (Open Access) -
CDK9 Inhibition with LDC526 Is an Effective Treatment for T-Cell Prolymphocytic Leukemia (T-PLL) in VitroIn: Blood , Jg. 130 2017, Nr. Suppl. 1, S. 1262
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Genomic profiling of T-cell Prolymphocytic Leukemia (T-PLL) identifies novel recurrent mutations in SAMHD1 and PTPRC
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Leipzig, 14.–18. Oktober 2016,In: Oncology Research and Treatment , Jg. 39 2016, Nr. Suppl. 3, S. 238 – 238 -
The AP-1 transcription factor BATF3 regulates MYC expression and is required for tumor cell survival in classical Hodgkin lymphoma and anaplastic large cell lymphomaIn: Haematologica / The Hematology Journal , Jg. 101 2016, Nr. S 5: You have access 10th International Symposium on Hodgkin Lymphoma, Cologne, Germany, October 22–25, 2016, Abstract Book, S. 2(Open Access)
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Einzelnukleotid Polymorphismen in Reparaturproteinen sind prognoserelevant für des Überleben von Kopf-Hals-Tumorpatienten nach postoperativer Radiochemotherapie mit Cisplatin (DKTK-ROG)
21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 191 2015, Nr. Suppl. 1 , S. 28 - S. 29 -
Chronic intermittent hypoxia triggers adaptive changes that promote protection against cell deathIn: European Journal of Cancer (EJC) , Jg. 50 2014, Nr. Suppl. 5, S. 51
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The transcriptome of hMSC from osteoporotic donors is distinct from hMSC of 80+ donors
ECTS 2012, 39th Annual Congress; 19-23 May 2012; Stockholm, Sweden,In: Bone: Official Journal of the International Bone and Mineral Society (IBMS) , Jg. 50 2012, Nr. Suppl. 1, S. S83 -
Modulation of Proliferation in MCF7 Cells by Regulated Expression of KLF2, 4, 6 and Ki-67 After Treatment With Zoledronic AcidIn: European Journal of Cancer (EJC) , Jg. 47 2011, Nr. Suppl. 1, S. 359
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Progranulin plasma levels predict time to first treatment and overall survival in chronic lymphocytic leukemia
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Comparing the pharmacological effects of the novel Locked Nucleic Acid (LNA) modified antisense Bcl-2 inhibitor SPC2996 and G3139 (oblimersen) in preclinical models of chronic lymphocytic leukemia
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Cryptochrome 1 (CRY1) promoter methylation is associated with good prognosis in B-cell chronic lymphocytic leukemia (CLL)
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Expanded CD8(+) T-cells of murine and human B-CLL are driven into a senescent KLRG1(+) effector memory phenotypeIn: Onkologie , Jg. 33 2010, Nr. Suppl. 6, S. 201
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Expanded CLL CD8(+) T-Cells Are Driven Into a Senescent KLRG1(+) Effector Memory PhenotypeIn: Blood , Jg. 116 2010, Nr. 21, S. 403
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Prevalence of B cell lymphoproliferative disorders in patients with chronic hepatitis C (CHC)
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The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie , Jg. 33 2010, Nr. Suppl. 6, S. 42 -
Locus-specific DNA methylation analysis by targeted deep bisulfite sequencingIn: Epigenome Editing: Methods and Protocols / Jeltsch, Albert; Rots, Marianne G. (Hrsg.) 2018, S. 351 – 366
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Anti-leukemic activity through CDK9 inhibition in T-cell prolymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,In: Oncology Research and Treatment , Jg. 42 2019, Nr. Supplement 4: Abstracts, S. 218DOI (Open Access)