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Geschäftsführende/r Direktor/in, Institut für Medizinische Strahlenbiologie
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2022 SS
- Kursus für Bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz, Teil III (PV)
- Kursus für Bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz, Teil II (WA) begleitende Vorlesung zum Kurs
- Neue Literatur der Zell- und Molekularbiologie für Med. Biologen
- Kursus für bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz Teil III (WA)
- Kursus für Bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz, Teil I (WA) (begleitende Vorlesung zum Kurs)
- Vorlesung des GRK 1739 (mit Gastsprechern)
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2021 WS
- Kursus für bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz Teil III (WA)
- Biologie für Mediziner
- Biologie für Mediziner
- Kursus für Bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz, Teil II (WA) begleitende Vorlesung zum Kurs
- Molekular- und Zellbiologie für Biomediziner
- Vorlesung des GRK 1739 (mit Gastsprechern)
- Kursus für Bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz, Teil III (PV)
- Modern Biomedicine/Beispiele biologischer Forschung (Teil 1)
- Kursus für Bildgebende Verfahren, Strahlenbehandlung, Strahlenschutz, Teil I (WA) (begleitende Vorlesung zum Kurs)
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2021 SS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin BreaksIn: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry Jg. 27 (2022) Nr. 5,
ISSN: 1420-3049Online Volltext: dx.doi.org/ (Open Access) -
Depletion of HIF-1α by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in HypoxiaIn: Cells Jg. 11 (2022) Nr. 10,
ISSN: 2073-4409Online Volltext: dx.doi.org/ (Open Access) -
Shift in g₁-checkpoint from atm-alone to a cooperative atm plus atr regulation with increasing dose of radiationIn: Cells Jg. 11 (2022) Nr. 1,
ISSN: 2073-4409Online Volltext: dx.doi.org/ (Open Access) -
An experimental platform for studying the radiation effects of laser accelerated protons on mammalian cellsIn: AIP Advances Jg. 11 (2021) Nr. 6,
ISSN: 2158-3226Online Volltext: dx.doi.org/ (Open Access) -
Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaksIn: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Jg. 867 (2021)
ISSN: 1879-3592; 1383-5718; 1388-2120Online Volltext: dx.doi.org/ -
Disruption of chromatin dynamics by hypotonic stress suppresses hr and shifts dsb processing to error-prone ssaIn: International Journal of Molecular Sciences (IJMS) Jg. 22 (2021) Nr. 20,
ISSN: 1422-0067; 1661-6596Online Volltext: dx.doi.org/ (Open Access) -
G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human CellsIn: Frontiers in Public Health Jg. 9 (2021)
ISSN: 2296-2565Online Volltext: dx.doi.org/ (Open Access) -
Loss of TGFB signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer typesIn: Science Translational Medicine Jg. 13 (2021) Nr. 580, S. eabc4465
ISSN: 1946-6242; 1946-6234Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
NTRK1/TrkA activation overrides the G₂ /M-checkpoint upon irradiationIn: Cancers Jg. 13 (2021) Nr. 23,
ISSN: 2072-6694Online Volltext: dx.doi.org/ (Open Access) -
New players in the regulation of DNA-PK activity : Survivin joins the crowdIn: Cancer Research Jg. 81 (2021) Nr. 9, S. 2270 - 2271
ISSN: 1538-7445; 0008-5472Online Volltext: dx.doi.org/ (Open Access) -
Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-JoiningIn: Radiation Research Jg. 195 (2021) Nr. 5, S. 412 - 426
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
Proficiency in homologous recombination repair is prerequisite for activation of G₂-checkpoint at low radiation dosesIn: DNA Repair Jg. 101 (2021) S. 103076
ISSN: 1568-7864; 1568-7856Online Volltext: dx.doi.org/ -
Strong shift to atr-dependent regulation of the g₂-checkpoint after exposure to high-let radiationIn: Life Jg. 11 (2021) Nr. 6,
ISSN: 2075-1729Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Biochemical evidence for Ku-independent backup pathways of NHEJIn: Nucleic Acids Research Jg. 48 (2020) Nr. 9, S. 5200
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
Chromosome breaks generated by low doses of ionizing radiation in G₂-phase are processed exclusively by gene conversionIn: DNA Repair Jg. 89 (2020) S. 102828
ISSN: 1568-7856; 1568-7864Online Volltext: dx.doi.org/ -
Complete Genome Sequence of the Deep-Sea Bacterium Moritella marina MP-1 (ATCC 15381)In: Microbiology Resource Announcements Jg. 9 (2020) Nr. 4, S. e01321 - 19
ISSN: 2576-098XOnline Volltext: dx.doi.org/ Online Volltext (Open Access) -
Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiationIn: Nucleic Acids Research Jg. 48 (2020) Nr. 6, S. 3396
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
SCFSKP² regulates APC/CCDH¹-mediated degradation of CTIP to adjust DNA-end resection in G₂-phaseIn: Cell Death and Disease Jg. 11 (2020) Nr. 7, S. 548
ISSN: 2041-4889Online Volltext: dx.doi.org/ (Open Access) -
Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52In: Nucleic Acids Research Jg. 48 (2020) Nr. 4, S. 1905 - 1924
ISSN: 1362-4962; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaksIn: Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis Jg. 815 (2019) S. 10 - 19
ISSN: 1873-135X; 0027-5107; 1386-1964; 1388-2112Online Volltext: dx.doi.org/ -
DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G₂-checkpoint in S-phase irradiated cellsIn: Scientific Reports Jg. 9 (2019) S. 14597
ISSN: 2045-2322Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Defined biological models of high-let radiation lesionsIn: Radiation Protection Dosimetry Jg. 183 (2019) Nr. 1-2, S. 60 - 68
ISSN: 1742-3406; 0144-8420Online Volltext: dx.doi.org/ -
Necessities in the processing of DNA double strand breaks and their effects on genomic instability and cancerIn: Cancers Jg. 11 (2019) Nr. 11, S. 1671
ISSN: 2072-6694Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G₂-phaseIn: Scientific Reports Jg. 9 (2019) S. 8255
ISSN: 2045-2322Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophagesIn: Journal of Lipid Research Jg. 60 (2019) Nr. 3, S. 506 - 515
ISSN: 1539-7262; 0022-2275Online Volltext: dx.doi.org/ (Open Access) -
Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasivenessIn: Journal of Experimental & Clinical Cancer Research Jg. 38 (2019) Nr. 1,
ISSN: 1756-9966; 0392-9078Online Volltext: dx.doi.org/ (Open Access) -
Abdominopelvic 1.5-T and 3.0-T MR imaging in healthy volunteers : Relationship to formation of DNA double-Strand breaksIn: Radiology Jg. 288 (2018) Nr. 2, S. 529 - 535
ISSN: 1527-1315; 0033-8419Online Volltext: dx.doi.org/ (Open Access) -
Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand BreaksIn: Molecular Cancer Therapeutics Jg. 17 (2018) Nr. 10, S. 2206 - 2216
ISSN: 1538-8514Online Volltext: dx.doi.org/ (Open Access) -
Intercellular communication of DNA damage and oxidative status underpin bystander effectsIn: International Journal of Radiation Biology Jg. 94 (2018) Nr. 8, S. 719 - 726
ISSN: 1362-3095; 0955-3002Online Volltext: dx.doi.org/ -
Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak ProtonsIn: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 12, S. 3779
ISSN: 1422-0067; 1661-6596Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer CellsIn: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 8, S. 2233
ISSN: 1422-0067; 1661-6596Online Volltext: dx.doi.org/ (Open Access) -
The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.In: BMC Cancer Jg. 18 (2018) S. 1190
ISSN: 1471-2407Online Volltext: dx.doi.org/ (Open Access) -
When a duck is not a duck : a new interdisciplinary synthesis for environmental radiation protectionIn: Environmental Research Jg. 162 (2018) S. 318 - 324
ISSN: 0013-9351; 1096-0953Online Volltext: dx.doi.org/ (Open Access) -
Activating Akt1 mutations alter DNA double strand break repair and radiosensitivityIn: Scientific Reports Jg. 7 (2017) S. 42700
ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access) -
Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancerIn: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 9, S. 1733 - 1744
ISSN: 0171-5216Online Volltext: dx.doi.org/ -
Wenn Stränge reißen : Wege der DNA-Doppelstrangbruch-ReparaturIn: Biospektrum Jg. 23 (2017) Nr. 5, S. 502 - 505
ISSN: 0947-0867; 1868-6249Online Volltext: dx.doi.org/ -
Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitmentIn: Nucleic Acids Research Jg. 44 (2016) Nr. 16, S. 7673 - 7690
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer : Cell cycle and proliferation-dependent regulationIn: Seminars in Cancer Biology Jg. 37-38 (2016) S. 51 - 64
ISSN: 1096-3650; 1044-579XOnline Volltext: dx.doi.org/ -
Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET)In: Free Radical Research Jg. 50 (2016) Nr. Suppl. 1, S. S64 - S78
ISSN: 1029-2470; 1071-5762; 8755-0199Online Volltext: dx.doi.org/ (Open Access) -
Non-DSB clustered DNA lesions. Does theory colocalize with the experiment?In: Radiation Physics and Chemistry Jg. 128 (2016) S. 26 - 35
ISSN: 0969-806XOnline Volltext: dx.doi.org/ -
Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET RadiationIn: Frontiers in Oncology Jg. 6 (2016) S. 163
ISSN: 2234-943XOnline Volltext: dx.doi.org/ -
Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beamsIn: Scientific Reports Jg. 6 (2016) S. 32441
ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access) -
VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break RepairIn: Molecular Cell Jg. 64 (2016) Nr. 1, S. 189 - 198
ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/ (Open Access) -
Alternative end-joining repair pathways are the ultimate backup for abrogated classical non-homologous end-joining and homologous recombination repair : Implications for the formation of chromosome translocationsIn: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Jg. 793 (2015) S. 166 - 175
ISSN: 1388-2120; 1879-3592; 1383-5718Online Volltext: dx.doi.org/ -
Alternative okazaki fragment ligation pathway by dna ligase IIIIn: Genes Jg. 6 (2015) Nr. 2, S. 385 - 398
ISSN: 2073-4425Online Volltext: dx.doi.org/ (Open Access) -
Balance shift between error-free and error prone DNA double-strand break repair as a novel mechanism of radiosensitization by nucleoside analogsIn: Cancer Research Jg. 75 (2015) Nr. Suppl. 15, S. 3629
ISSN: 0008-5472; 1538-7445Online Volltext: dx.doi.org/ -
Bystander effects as manifestation of intercellular communication of DNA damage and of the cellular oxidative statusIn: Cancer Letters Jg. 356 (2015) Nr. 1, S. 58 - 71
ISSN: 1872-7980Online Volltext: dx.doi.org/ -
DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar EfficiencyIn: Photochemistry and Photobiology Jg. 91 (2015) Nr. 5, S. 1173 - 1180
ISSN: 0031-8655Online Volltext: dx.doi.org/ -
Inhibition of homologous recombination and promotion of mutagenic repair of DNA double-strand breaks underpins arabinoside-nucleoside analogue radiosensitizationIn: Molecular Cancer Therapeutics Jg. 14 (2015) Nr. 6, S. 1424 - 1433
ISSN: 1538-8514; 1535-7163Online Volltext: dx.doi.org/ (Open Access) -
Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cellsIn: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Jg. 793 (2015) S. 2 - 8
ISSN: 1388-2120; 1383-5780; 1879-3592Online Volltext: dx.doi.org/ -
Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joiningIn: DNA Repair Jg. 31 (2015) S. 29 - 40
ISSN: 1568-7864Online Volltext: dx.doi.org/ -
The contribution of thermally labile sugar lesions to DNA double-strand break formation in cells grown in the presence of BrdUIn: International Journal of Radiation Biology Jg. 91 (2015) Nr. 4, S. 312 - 320
ISSN: 0955-3002Online Volltext: dx.doi.org/ -
The yield of DNA double strand breaks determined after exclusion of those forming from heat-labile lesions predicts tumor cell radiosensitivity to killingIn: Radiotherapy and Oncology (The Green Journal) Jg. 116 (2015) Nr. 3, S. 366 - 373
ISSN: 1879-0887; 0167-8140Online Volltext: dx.doi.org/ -
Break-induced replication repair of damaged forks induces genomic duplications in human cellsIn: Science Jg. 343 (2014) Nr. 6166, S. 88 - 91
ISSN: 0036-8075Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joiningIn: Nucleic Acids Research Jg. 42 (2014) Nr. 10, S. 6380 - 6392
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradationIn: The FEBS Journal Jg. 281 (2014) Nr. Suppl. 1, S. 82
ISSN: 1742-4658; 1742-464XOnline Volltext: dx.doi.org/ -
The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradationIn: Cell Cycle Jg. 13 (2014) Nr. 6, S. 919 - 927
ISSN: 1551-4005Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancerIn: Translational Cancer Research Jg. 2 (2013) Nr. 3, S. 163 - 177
ISSN: 2219-6803; 2218-676XOnline Volltext: dx.doi.org/ -
DNA Ligases I and III Cooperate in Alternative Non-Homologous End-Joining in VertebratesIn: PLoS ONE Jg. 8 (2013) Nr. 3, S. e59505
ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapyIn: Frontiers in Oncology Jg. 3 (2013) S. 113
ISSN: 2234-943XOnline Volltext: dx.doi.org/ Online Volltext (Open Access) -
DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceIn: Nucleic Acids Research Jg. 41 (2013) Nr. 16, S. 7589 - 7605
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
Effects of chromatin decondensation on alternative NHEJIn: DNA Repair Jg. 12 (2013) Nr. 11, S. 972 - 981
ISSN: 1568-7856; 1568-7864Online Volltext: dx.doi.org/ -
Inhibition of PARP1 by small interfering RNA enhances docetaxel activity against human prostate cancer PC3 cellsIn: Biochemical and Biophysical Research Communications Jg. 442 (2013) Nr. 1-2, S. 127 - 132
ISSN: 0006-291X; 1090-2104Online Volltext: dx.doi.org/ -
Lipofection and nucleofection of substrate plasmid can generate widely different readings of DNA end-joining efficiency in different cell linesIn: DNA repair Jg. 12 (2013) Nr. 2, S. 148 - 160
ISSN: 1568-7856; 1568-7864Online Volltext: dx.doi.org/ -
Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ionsIn: Radiation Oncology Jg. 8 (2013) Nr. 1, S. 77
ISSN: 1748-717XOnline Volltext: dx.doi.org/ (Open Access) -
Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetesIn: PLoS Pathogens Jg. 9 (2013) Nr. 10,
ISSN: 1553-7374; 1553-7366Online Volltext: dx.doi.org/ (Open Access) -
A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects : Overview of study and results presentationIn: International Journal of Radiation Biology Jg. 88 (2012) Nr. 10, S. 763 - 769
ISSN: 1362-3095; 1362-3095Online Volltext: dx.doi.org/ -
Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRETIn: Biochemical Journal Jg. 443 (2012) Nr. 3, S. 701 - 709
ISSN: 1470-8728; 0264-6021; 0006-2936Online Volltext: dx.doi.org/ -
Dependence of adaptive response and its bystander transmission on the genetic background of tested cellsIn: International Journal of Radiation Biology Jg. 88 (2012) Nr. 10, S. 720 - 726
ISSN: 1362-3095; 0955-3002Online Volltext: dx.doi.org/ -
Functional redundancy between DNA ligases i and III in DNA replication in vertebrate cellsIn: Nucleic Acids Research Jg. 40 (2012) Nr. 6, S. 2599 - 2610
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
Inhibition of B-NHEJ in plateau-phase cells is not a direct consequence of suppressed growth factor signalingIn: International Journal of Radiation Oncology, Biology, Physics Jg. 84 (2012) Nr. 2, S. e237 - e243
ISSN: 0360-3016; 1879-355XOnline Volltext: dx.doi.org/ -
Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatinIn: Genome Integrity Jg. 3 (2012) S. 4
ISSN: 2041-9414Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutronsIn: Radiation Research Jg. 178 (2012) Nr. 6, S. 581 - 590
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
Targeting DNA damage and repair : Embracing the pharmacological era for successful cancer therapyIn: Pharmacology & Therapeutics Jg. 133 (2012) Nr. 3, S. 334 - 350
ISSN: 0163-7258; 1879-016XOnline Volltext: dx.doi.org/ -
The impact of serotonin on the development of bystander damage assessed by γ-H2AX foci analysisIn: International Journal of Radiation Biology Jg. 88 (2012) Nr. 10, S. 777 - 780
ISSN: 1362-3095; 0955-3002Online Volltext: dx.doi.org/ -
Induction and repair of DNA double strand breaks : The increasing spectrum of non-homologous end joining pathwaysIn: Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis Jg. 711 (2011) Nr. 1-2, S. 61 - 72
ISSN: 0027-5107; 1873-135X; 1386-1964; 1388-2112Online Volltext: dx.doi.org/ -
Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repairIn: Nucleic Acids Research Jg. 39 (2011) Nr. 19, S. 8416 - 8429
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
Widespread dependence of backup NHEJ on growth state : Ramifications for the use of DNA-PK inhibitorsIn: International Journal of Radiation Oncology, Biology, Physics Jg. 79 (2011) Nr. 2, S. 540 - 548
ISSN: 0360-3016; 1879-355XOnline Volltext: dx.doi.org/ -
Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cellsIn: Cancer Research Jg. 70 (2010) Nr. 21, S. 8498 - 8506
ISSN: 0008-5472; 1538-7445Online Volltext: dx.doi.org/ -
Initial characterization of a low-molecular-weight factor enhancing the checkpoint responseIn: Radiation Research Jg. 174 (2010) Nr. 4, S. 424 - 435
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
Investigation of bystander effects in hybrid cells by means of cell fusion and premature chromosome condensation inductionIn: Radiation Research Jg. 173 (2010) Nr. 6, S. 789 - 801
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
New partners for Chk1In: Cell Cycle Jg. 9 (2010) Nr. 11, S. 2061 - 2062
ISSN: 1551-4005Online Volltext: dx.doi.org/ -
The anatomy and cell cycle evolution of DNA damage signaling and repair fociIn: Cell Cycle Jg. 9 (2010) Nr. 3, S. 444 - 445
ISSN: 1538-4101; 1551-4005Online Volltext: dx.doi.org/ -
Backup pathways of NHEJ in cells of higher eukaryotes : Cell cycle dependenceIn: Radiotherapy and Oncology (The Green Journal) Jg. 92 (2009) Nr. 3, S. 310 - 315
ISSN: 1879-0887; 0167-8140Online Volltext: dx.doi.org/ -
Extensive repair of DNA double-strand breaks in cells deficient in the DNA-PK-dependent pathway of NHEJ after exclusion of heat-labile sitesIn: Radiation Research Jg. 172 (2009) Nr. 2, S. 152 - 164
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
DNA double strand break repair inhibition as a cause of heat radiosensitization : Re-evaluation considering backup pathways of NHEJIn: International Journal of Hyperthermia Jg. 24 (2008) Nr. 1, S. 17 - 29
ISSN: 0265-6736; 1464-5157Online Volltext: dx.doi.org/ -
Enhanced use of backup pathways of NHEJ in G₂ in Chinese hamster mutant cells with defects in the classical pathway of NHEJIn: Radiation Research Jg. 170 (2008) Nr. 4, S. 512 - 520
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin.In: Nucleic Acids Research Jg. 36 (2008) Nr. 17, S. 5678 - 5694
ISSN: 1362-4962; 0301-5610Online Volltext: dx.doi.org/ (Open Access) -
Histone H1 functions as a stimulatory factor in backup pathways of NHEJIn: Nucleic Acids Research Jg. 36 (2008) Nr. 5, S. 1610 - 1623
ISSN: 0301-5610; 1362-4962Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repairIn: International Journal of Oncology Jg. 33 (2008) Nr. 4, S. 871 - 879
ISSN: 1019-6439; 1791-2423 -
Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2In: DNA Repair Jg. 7 (2008) Nr. 2, S. 329 - 338
ISSN: 1568-7864; 1568-7856Online Volltext: dx.doi.org/ -
Homology-directed repair is required for the development of radioresistance during S phase : Interplay between double-strand break repair and checkpoint responseIn: Radiation Research Jg. 167 (2007) Nr. 1, S. 1 - 11
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
Low levels of DNA ligases III and IV sufficient for effective NHEJIn: Journal of Cellular Physiology Jg. 213 (2007) Nr. 2, S. 475 - 483
ISSN: 0095-9898; 1097-4652Online Volltext: dx.doi.org/ -
Marked Dependence on Growth State of Backup Pathways of NHEJIn: International Journal of Radiation Oncology, Biology, Physics Jg. 68 (2007) Nr. 5, S. 1462 - 1470
ISSN: 0360-3016; 1879-355XOnline Volltext: dx.doi.org/ -
Computational methods for analysis of foci : Validation for radiation-induced γ-H2AX foci in human cellsIn: Radiation Research Jg. 165 (2006) Nr. 1, S. 113 - 124
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathwaysIn: Nucleic Acids Research Jg. 34 (2006) Nr. 21, S. 6170 - 6182
ISSN: 0301-5610; 1362-4962Online Volltext: dx.doi.org/ (Open Access) -
Cell line specific modulation of connexin43 expression after exposure to ionizing radiationIn: Cell Communication and Adhesion Jg. 12 (2005) Nr. 5-6, S. 249 - 259
ISSN: 1541-9061; 1543-5180Online Volltext: dx.doi.org/ -
Checkpoint abrogation in G₂ compromises repair of chromosomal breaks in ataxia telangiectasia cellsIn: Cancer Research Jg. 65 (2005) Nr. 24, S. 11292 - 11296
ISSN: 1538-7445; 0008-5472Online Volltext: dx.doi.org/ (Open Access) -
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitorsIn: Journal of Cellular Physiology Jg. 202 (2005) Nr. 2, S. 492 - 502
ISSN: 0021-9541; 1097-4652Online Volltext: dx.doi.org/ -
DNA ligase III as a candidate component of backup pathways of nonhomologous end joiningIn: Cancer Research Jg. 65 (2005) Nr. 10, S. 4020 - 4030
ISSN: 1538-7445; 0008-5472Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Interferon alpha 2a downregulates VEGF expression through PI3 kinase and MAP kinase signaling pathwaysIn: Journal of Cancer Research and Clinical Oncology Jg. 131 (2005) Nr. 3, S. 169 - 178
ISSN: 1432-1335; 0171-5216Online Volltext: dx.doi.org/ -
Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblastsIn: Cancer Research Jg. 65 (2005) Nr. 22, S. 10223 - 10232
ISSN: 1538-7445; 0008-5472Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joiningIn: Cancer Research Jg. 64 (2004) Nr. 19, S. 7139 - 7143
ISSN: 1538-7445; 0008-5472Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Backup pathways of NHEJ are suppressed by DNA-PKIn: Journal of Cellular Biochemistry Jg. 92 (2004) Nr. 4, S. 781 - 794
ISSN: 0275-3723; 1097-4644Online Volltext: dx.doi.org/ -
Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaksIn: Oncogene Jg. 23 (2004) Nr. 3, S. 824 - 834
ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Evidence for an S-Phase checkpoint regulating DNA replication after heat shock : A reviewIn: International Journal of Hyperthermia Jg. 20 (2004) Nr. 2, S. 240 - 249
ISSN: 0265-6736; 1464-5157Online Volltext: dx.doi.org/ -
Mechanisms of DNA double strand break repair and chromosome aberration formationIn: Cytogenetic and Genome Research Jg. 104 (2004) Nr. 1-4, S. 14 - 20
ISSN: 1424-859X; 0301-0171Online Volltext: dx.doi.org/ -
An overactivated ATR/CHK1 pathway is responsible for the prolonged G ₂ accumulation in irradiated AT cellsIn: The Journal of Biological Chemistry (JBC) Jg. 278 (2003) Nr. 33, S. 30869 - 30874
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ Online Volltext (Open Access) -
Caffeine Could Not Efficiently Sensitize Homologous Recombination Repair-Deficient Cells to Ionizing Radiation-Induced KillingIn: Radiation Research Jg. 159 (2003) Nr. 3, S. 420 - 425
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
Caffeine-Induced Radiosensitization is Independent of Nonhomologous End Joining of DNA Double-Strand BreaksIn: Radiation Research Jg. 159 (2003) Nr. 3, S. 426 - 432
ISSN: 0033-7587; 1938-5404Online Volltext: dx.doi.org/ -
DNA damage checkpoint control in cells exposed to ionizing radiationIn: Oncogene Jg. 22 (2003) Nr. 37, S. 5834 - 5847
ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Targeting Angiogenic Processes by Combination Low-Dose Paclitaxel and Radiation TherapyIn: American Journal of Clinical Oncology Jg. 26 (2003) Nr. 3, S. e45 - e53
ISSN: 0277-3732; 1537-453XOnline Volltext: dx.doi.org/ -
hTERT associates with human telomeres and enhances genomic stability and DNA repairIn: Oncogene Jg. 22 (2003) Nr. 1, S. 131 - 146
ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
An ATM-independent S-phase checkpoint response involves CHK1 pathwayIn: Cancer Research Jg. 62 (2002) Nr. 6, S. 1598 - 1603
ISSN: 0008-5472; 1538-7445 -
CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicityIn: Cell Cycle Jg. 1 (2002) Nr. 4, S. 267 - 272
ISSN: 1554-8627; 1551-4005 -
DNA-PKcs subunits in radiosensitization by hyperthermia on hepatocellular carcinoma hepG₂ cell lineIn: World Journal of Gastroenterology Jg. 8 (2002) Nr. 5, S. 797 - 803
ISSN: 2219-2840; 1007-9327Online Volltext: dx.doi.org/ (Open Access) -
Effects of hyperthermia on p53 protein expression and activityIn: Journal of Cellular Physiology Jg. 190 (2002) Nr. 3, S. 365 - 374
ISSN: 0095-9898; 1097-4652Online Volltext: dx.doi.org/ -
Ku affects the ATM-dependent S phase checkpoint following ionizing radiationIn: Oncogene Jg. 21 (2002) Nr. 41, S. 6377 - 6381
ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ (Open Access) -
Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiationIn: Cancer research : Jg. 62 (2002) Nr. 21, S. 6031 - 6034
ISSN: 0008-5472; 1538-7445 -
Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.In: Cancer Research Jg. 62 (2002) Nr. 9, S. 2483 - 2487
ISSN: 0008-5472; 1538-7445 -
Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joiningIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 98 (2001) Nr. 15, S. 8644 - 8649
ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis groupIn: Oncogene Jg. 20 (2001) Nr. 18, S. 2212 - 2224
ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Evidence for factors modulating radiation-induced G2-delay : potential application as radioprotectors.In: Physica Medica: European Journal of Medical Physics Jg. 17 (2001) Nr. Suppl. 1, S. 205 - 209
ISSN: 1120-1797; 1724-191X -
Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cellsIn: Nucleic Acids Research Jg. 29 (2001) Nr. 8, S. 1653 - 1660
ISSN: 0305-1048; 1362-4962Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Inhibition of DNA replication by tirapazamineIn: Cancer Research Jg. 61 (2001) Nr. 14, S. 5425 - 5431
ISSN: 0008-5472; 1538-7445 -
Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2In: Cancer Research Jg. 61 (2001) Nr. 1, S. 270 - 277
ISSN: 0008-5472; 1538-7445 -
RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrateIn: International Journal of Radiation Biology (RAB) Jg. 77 (2001) Nr. 5, S. 593 - 607
ISSN: 0955-3002; 1362-3095Online Volltext: dx.doi.org/ -
Regulation of DNA Replication after Heat Shock by Replication Protein A-Nucleolin InteractionsIn: The Journal of Biological Chemistry (JBC) Jg. 276 (2001) Nr. 23, S. 20579 - 20588
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ (Open Access) -
Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinaseIn: Cancer Research Jg. 61 (2001) Nr. 23, S. 8554 - 8563
ISSN: 0008-5472; 1538-7445 -
Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomasIn: Journal of Clinical Oncology Jg. 19 (2001) Nr. 8, S. 2189 - 2200
ISSN: 0732-183X; 1527-7755Online Volltext: dx.doi.org/ -
The Radioresistance to Killing of A1-5 Cells Derives from Activation of the Chk1 PathwayIn: The Journal of Biological Chemistry (JBC) Jg. 276 (2001) Nr. 21, S. 17693 - 17698
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ Online Volltext (Open Access) -
DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus.In: Cancer Research Jg. 60 (2000) Nr. 5, S. 1245 - 1253
ISSN: 0008-5472; 1538-7445 -
Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells : Reduced caffeine radiosensitization in XRCC2 and XRCC3 mutantsIn: Oncogene Jg. 19 (2000) Nr. 50, S. 5788 - 5800
ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Hyperthermia does not affect rejoining of DNA double-strand breaks in a cell-free assayIn: International Journal of Radiation Biology (RAB) Jg. 76 (2000) Nr. 3, S. 313 - 326
ISSN: 0955-3002; 1362-3095Online Volltext: dx.doi.org/ -
The catalytic subunit DNA-dependent protein kinase (DNA-PKcs) facilitates recovery from radiation-induced inhibition of DNA replicationIn: Nucleic Acids Research Jg. 28 (2000) Nr. 5, S. 1183 - 1192
ISSN: 0305-1048; 1362-4962Online Volltext: dx.doi.org/ (Open Access) -
Preface to the IJRB 60th anniversary special issue “back to our future”In: International Journal of Radiation Biology Jg. 95 (2019) Nr. 7, 60th Anniversary Special Issue: Back to our Future, S. 799 - 801
ISSN: 1362-3095; 0955-3002Online Volltext: dx.doi.org/ -
On the Importance of Ultrastructural Organization of DNA Double Strand Break-Repair FociIn: Strahlentherapie und Onkologie Jg. 194 (2018) Nr. Suppl. 1, S. 27 - S28
ISSN: 1439-099XOnline Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ -
The role of protein kinase B alpha (Akt1) in the cellular response to ionizing radiationIn: Strahlentherapie und Onkologie / 21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg Jg. 191 (2015) Nr. Suppl.1, S. S74 - S75
ISSN: 0179-7158; 1439-099XOnline Volltext: dx.doi.org/ -
Dihydroartemisinin exerts context-dependent lethal effects in combination with ionizing radiation
19. Jahreskongress der Deutschen Gesellschaft für Radioonkologie; 9. bis 12. Mai 2013, Berlin,In: Strahlentherapie und Onkologie Jg. 189 (2013) Nr. SUPPL. 1, S. 128 - 129
ISSN: 0179-7158; 1439-099XOnline Volltext: dx.doi.org/ -
Processing-challenges generated by clusters of DNA double-strand breaks underpin increased effectiveness of high-LET radiation and chromothripsisIn: Chromosome Translocation / Yu, Zhang (Hrsg.) 2018, S. 149 - 168
ISBN: 978-981-13-0592-4; 978-981-13-0593-1Online Volltext: dx.doi.org/ -
Analysis of Inhibition of DNA Replication in Irradiated Cells Using the SV40 Based In Vitro Assay of DNA ReplicationIn: DNA Repair Protocols / Bjergbæk, Lotte (Hrsg.) 2012, S. 591 - 602
ISBN: 978-1-61779-997-6; 978-1-61779-998-3 ISSN: 1064-3745Online Volltext: dx.doi.org/ -
In vitro rejoining of double strand breaks in genomic DNAIn: DNA Repair Protocols / Bjergbæk, Lotte (Hrsg.) 2012, S. 471 - 484
ISBN: 978-1-61779-997-6; 978-1-61779-998-3 ISSN: 1064-3745Online Volltext: dx.doi.org/ -
Application of alkaline sucrose gradient centrifugation in the analysis of DNA replication after DNA damageIn: DNA Replication: Methods and Protocols / Vengrova, Sonya; Dalgaard, Jacob Z. (Hrsg.) 2009, S. 329 - 342
ISBN: 978-1-60327-814-0; 978-1-4939-5660-9; 978-1-60327-815-7 ISSN: 1940-6029Online Volltext: dx.doi.org/ -
Plasmid-based assays for DNA end-joining in vitroIn: DNA Repair Protocols: Mammalian Systems / Henderson, Daryl S. (Hrsg.) 2006, S. 123 - 131
ISBN: 978-1-58829-513-2; 978-1-61737-611-5; 978-1-59259-973-8Online Volltext: dx.doi.org/