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Biologie / ZMB / Bioinformatics & Computational Biophysics
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Universitätsstr. 2-5
45141 Essen
45141 Essen
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S03 S03 A26
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Funktionen
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
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Professor/in, Bioinformatik and Computational Biophysics
Aktuelle Veranstaltungen
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SoSe 2025
- High-throughput sequencing analyses in biomedicine
- Bioinformatik
- Mathematical Models in Immunology and Cancer Research
- Data presentation
- Seminar High-throughput sequencing analyses in biomedicine
- Bayes-Statistics: Concepts and Practice
- E3 - Bio - Bayes-Statistics: Concepts and Practice - Cr. 2-2
- Scientific Writing
- ZJA40102 Bioinformatik
- Current Research in Bioinformatics
- Anleitung zum selbstständigen wiss. Arbeiten
Vergangene Veranstaltungen (max. 10)
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WiSe 2024
- Anleitung zum selbstständigen wiss. Arbeiten
- Modern Biomedicine/Beispiele biologischer Forschung (Teil 1)
- Lehramtspraktikum (LA Ma)
- Bioinformatics
- Current Research in Bioinformatics
- ZJD91022 Scientific Writing
- Biologische Forschung mit dem Computer
- ZJD91022 Scientific Writing
- Computational Biophysics
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SoSe 2024
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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BAYAS : simplifying access to Bayesian analysis for biologistsIn: Bioinformatics , Jg. 41 2025, Nr. 6, btaf276DOI (Open Access)
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Bath : A Bayesian approach to analyze epigenetic transitions reveals a dual role of H3K27me3 in chondrogenesisIn: Epigenetics and Chromatin , Jg. 18 2025, Nr. 1, 38DOI (Open Access)
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HBV shows different levels of adaptation to HLA class I-associated selection pressure correlating with markers of replicationIn: Journal of Hepatology , Jg. 82 2025, Nr. 5, S. 805 – 815DOI (Open Access)
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Quantitative Visualisierung von HTseq-DatenIn: Biospektrum , Jg. 31 2025, Nr. 1, S. 49 – 51DOI (Open Access)
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Cell-type-specific expression analysis of liver transcriptomics with clinical parameters to decipher the cause of intrahepatic inflammation in chronic hepatitis BIn: iMeta , Jg. 3 2024, Nr. 4, e221DOI (Open Access)
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How Do Molecular Tweezers Bind to Proteins? : Lessons from X-ray CrystallographyIn: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry , Jg. 29 2024, Nr. 8, 1764DOI (Open Access)
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Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1In: Journal of Medical Virology , Jg. 96 2024, Nr. 7, e29789DOI (Open Access)
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Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretionIn: Nature Cardiovascular Research , Jg. 3 2024, Nr. 5, S. 525 – 540DOI (Open Access)
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scBubbletree: computational approach for visualization of single cell RNA-seq dataIn: BMC Bioinformatics , Jg. 25 2024, Nr. 1, 302DOI (Open Access)
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Increasing information gain in animal research by improving statistical model accuracyIn: Journal of Physics: Conference Series (JPCONF) , Jg. 2514 2023, Nr. 1, 012021DOI (Open Access)
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Sequence diversity of hepatitis D virus in MongoliaIn: Frontiers in Medicine , Jg. 10 2023, 1108543DOI (Open Access)
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio , Jg. 14 2023, Nr. 6, e02357-23DOI, Online Volltext (Open Access)
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Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinomaIn: Journal for ImmunoTherapy of Cancer , Jg. 10 2022, Nr. 1, e003198DOI, Online Volltext (Open Access)
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Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groupsIn: Beilstein Journal of Organic Chemistry , Jg. 18 2022, S. 1322 – 1331DOI (Open Access)
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DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinomaIn: Oncogene , Jg. 41 2022, Nr. 1, S. 37 – 45DOI (Open Access)
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Dissecting drivers of immune activation in chronic HIV-1 infectionIn: eBioMedicine , Jg. 83 2022, 104182DOI (Open Access)
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances , Jg. 12 2022, Nr. 53, S. 34176 – 34184DOI (Open Access)
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HAMdetector : A Bayesian regression model that integrates information to detect HLA-associated mutationsIn: Bioinformatics , Jg. 38 2022, Nr. 9, S. 2428 – 2436DOI (Open Access)
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Immune escape pathways from the HBV core₁₈₋₂₇ CD8 T cell response are driven by individual HLA class I allelesIn: Frontiers in Immunology , Jg. 13 2022, 1045498DOI (Open Access)
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A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19In: Frontiers in Cellular and Infection Microbiology , Jg. 11 2021, 747816DOI, Online Volltext (Open Access)
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BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytesIn: Cancer Immunology, Immunotherapy , Jg. 70 2021, Nr. 6, S. 1635 – 1647DOI (Open Access)
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Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal TransitionIn: Journal of Investigative Dermatology , Jg. 141 2021, Nr. 7, S. 1675 – 1686.e4DOI (Open Access)
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Classifier uncertainty : Evidence, potential impact, and probabilistic treatmentIn: PeerJ Computer Science , Jg. 7 2021, S. e398DOI (Open Access)
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Comprehensive Comparison of RNA-Seq Data of SARS-CoV-2, SARS-CoV and MERS-CoV Infections : Alternative Entry Routes and Innate Immune ResponsesIn: Frontiers in Immunology , Jg. 12 2021, 656433DOI, Online Volltext (Open Access)
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Epigenetic mechanisms mediating cell state transitions in chondrocytesIn: Journal of Bone and Mineral Research (JBMR) , Jg. 36 2021, Nr. 5, S. 968 – 985DOI, Online Volltext (Open Access)
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Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axisIn: Cell Death and Disease , Jg. 12 2021, Nr. 1, 34DOI, Online Volltext (Open Access)
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Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamicsIn: The Journal of Immunology (JI) , Jg. 206 2021, Nr. 12, S. 2839 – 2851DOI (Open Access)
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Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic CellsIn: Frontiers in Immunology , Jg. 11 2021, 607889DOI, Online Volltext (Open Access)
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Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdownIn: iScience , Jg. 24 2021, Nr. 11, 103366DOI (Open Access)
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Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2In: BMC Public Health , Jg. 21 2021, Nr. 1, 1178DOI, Online Volltext (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications , Jg. 12 2021, Nr. 1, S. 1505DOI, Online Volltext (Open Access)
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UMI or not UMI, that is the question for scRNA-seq zero-inflationIn: Nature Biotechnology , Jg. 39 2021, Nr. 2, S. 158 – 159DOI, Online Volltext (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances , Jg. 10 2020, Nr. 48, S. 28711 – 28719DOI (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances , Jg. 10 2020, Nr. 48, S. 28711 – 28719DOI (Open Access)
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An altered heparan sulfate structure in the articular cartilage protects against osteoarthritisIn: Osteoarthritis and Cartilage , Jg. 28 2020, Nr. 7, S. 977 – 987DOI (Open Access)
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Bayesian Data Integration Questions Classic Study on Protease Self-Digest KineticsIn: ACS Omega , Jg. 5 2020, Nr. 25, S. 15162 – 15168DOI (Open Access)
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Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfateIn: Matrix Biology , Jg. 39 2020, S. 43 – 59DOI (Open Access)
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Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19In: Frontiers in Immunology , Jg. 11 2020DOI, Online Volltext (Open Access)
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IgGeneUsage : differential gene usage in immune repertoiresIn: Bioinformatics , Jg. 36 2020, Nr. 11, S. 3590 – 3591
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Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell CarcinomaIn: Clinical Cancer Research , Jg. 26 2020, Nr. 9, S. 2257 – 2267DOI (Open Access)
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Rapid uptake of pre-exposure prophylaxis (PrEP) after significant price reduction in Germany highlights importance of PrEP accessibilityIn: AIDS Research and Human Retroviruses 2020
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Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophyIn: Developmental Biology , Jg. 457 2020, Nr. 1, S. 104 – 118DOI (Open Access)
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intePareto : an R package for integrative analyses of RNA-Seq and ChIP-Seq data
International Conference on Intelligent Biology and Medicine (ICIBM 2020), 9.-10.08.2020, Virtual,In: BMC Genomics , Jg. 21 2020, Nr. Supplement 11, S. 802DOI (Open Access) -
A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism , Jg. 1 2019, Nr. 2, S. 236 – 250DOI (Open Access)
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A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitudeIn: Chemical Communications: ChemComm , Jg. 55 2019, Nr. 1, S. 111 – 114
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Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bonesIn: PLoS ONE , Jg. 14 2019, Nr. 8, S. e0218230DOI, Online Volltext (Open Access)
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Differential escape of HCV from CD8⁺ T cell selection pressure between China and Germany depends on the presenting HLA class I moleculeIn: Journal of Viral Hepatitis , Jg. 26 2019, Nr. 1, S. 73 – 82DOI (Open Access)
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Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases (JID) , Jg. 219 2019, Nr. 3, S. 497 – 508DOI (Open Access)
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Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population LevelIn: Gastroenterology , Jg. 156 2019, Nr. 6, S. 1820 – 1833DOI (Open Access)
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Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly : Recent Advances and PerspectivesIn: ACS Infectious Diseases , Jg. 5 2019, Nr. 5, S. 713 – 724
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Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDVIn: Journal of Hepatology , Jg. 70 2019, Nr. Suppl. 1, S. e21
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Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cellsIn: Journal of Virology , Jg. 92 2018, Nr. 13, e01891-17DOI (Open Access)
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Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood , Jg. 131 2018, Nr. 5, S. 546 – 557DOI (Open Access)
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Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodiesIn: Archives of Virology , Jg. 163 2018, Nr. 12, S. 3303 – 3315
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Illumina sequencing for the identification of filamentous bulking and foaming bacteria in industrial activated sludge plantsIn: International Journal of Environmental Science and Technology (IJEST) , Jg. 15 2018, Nr. 6, S. 1139 – 1158
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Locating Large, Flexible Ligands on ProteinsIn: Journal of Chemical Information and Modeling , Jg. 58 2018, Nr. 2, S. 315 – 327DOI, Online Volltext (Open Access)
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Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wingIn: eLife , Jg. 7 2018, S. e33033DOI (Open Access)
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Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter ProteinIn: ChemBioChem , Jg. 19 2018, Nr. 6, S. 591 – 595
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Signaling systems affecting the severity of multiple osteochondromasIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) , Jg. 111 2018, S. 71 – 81DOI (Open Access)
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Trade-off shapes diversity in eco-evolutionary dynamicsIn: eLife , Jg. 7 2018, S. e36273DOI (Open Access)
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Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated releaseIn: Journal of Cell Science , Jg. 130 2017, Nr. 19, S. 3261 – 3271DOI (Open Access)
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Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infectionIn: Retrovirology , Jg. 14 2017, 42DOI (Open Access)
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Quantitative Assessment of Molecular Dynamics Sampling for Flexible SystemsIn: Journal of Chemical Theory and Computation (JCTC) , Jg. 13 2017, Nr. 2, S. 400 – 414
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Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology , Jg. 13 2017, Nr. 1, e1005362DOI (Open Access)
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Role of Gag mutations in PI resistance in the Swiss HIV cohort study : bystanders or contributors?In: Journal of Antimicrobial Chemotherapy , Jg. 72 2017, Nr. 3, S. 866 – 875DOI (Open Access)
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Protistan community analysis : key findings of a large scale molecular samplingIn: ISME Journal , Jg. 10 2016, S. 2269 – 2279DOI (Open Access)
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SeqFeatR for the Discovery of Feature-Sequence AssociationsIn: PLoS ONE , Jg. 11 2016, Nr. 1, S. e0146409DOI (Open Access)
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Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection PressureIn: Hepatology , Jg. 62 2015, Nr. 1, S. 47 – 56DOI (Open Access)
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AmpliconDuo : a split-sample filtering protocol for high-throughput amplicon sequencing of microbial communitiesIn: PLoS ONE , Jg. 10 2015, Nr. 11, S. e0141590DOI (Open Access)
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Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centersIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 112 2015, Nr. 38, S. E5281 – E5289DOI (Open Access)
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Parameters influencing baseline HIV-1 genotypic tropism testing related to clinical outcome in patients on maravirocIn: PLoS ONE , Jg. 10 2015, Nr. 5, S. e0125502DOI (Open Access)
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Pareto optimization identifies diverse set of phosphorylation signatures predicting response to treatment with dasatinibIn: PLoS ONE , Jg. 10 2015, Nr. 6, S. e0128542DOI (Open Access)
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Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry , Jg. 36 2015, Nr. 6, S. 2379 – 2392DOI (Open Access)
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A simple structure-based model for the prediction of HIV-1 co-receptor tropismIn: BioData Mining , Jg. 7 2014, S. 14DOI (Open Access)
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Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'In: Virologica Sinica , Jg. 29 2014, Nr. 1, S. 40 – 47
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HLA-B*27 is protective against HCV genotype 1 and 3 and associated with targeting of distinct genotype-specific CD8(+) cell epitopesIn: Journal of Hepatology , Jg. 60 2014, Nr. Suppl. 1, S. 140
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Identification of Significant Features by the Global Mean Rank TestIn: PLoS ONE , Jg. 9 2014, Nr. 8, S. e104504DOI (Open Access)
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Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-PeptidaseIn: PLoS Computational Biology , Jg. 10 2014, Nr. 7, S. e1003707DOI (Open Access)
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A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 GenomesIn: PLoS ONE , Jg. 8 2013, Nr. 3, S. e58804DOI, Online Volltext (Open Access)
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A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of armsIn: Organic and Biomolecular Chemistry , Jg. 11 2013, Nr. 10, S. 1631 – 1639
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Correction: A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 Genomes.In: PLoS ONE , Jg. 8 2013, Nr. 12DOI (Open Access)
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Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE , Jg. 8 2013, Nr. 6, S. e65346DOI, Online Volltext (Open Access)
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Inference of global HIV-1 sequence patterns and preliminary feature analysisIn: Virologica Sinica , Jg. 28 2013, Nr. 4, S. 228 – 238
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Novel Algorithm for Non-Invasive Assessment of Fibrosis in NAFLDIn: PLoS ONE , Jg. 8 2013, Nr. 4, S. e62439DOI (Open Access)
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The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovirIn: Antiviral Research , Jg. 97 2013, Nr. 2, S. 93 – 100
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Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure , Jg. 21 2013, Nr. 10, S. 1769 – 1777DOI (Open Access)
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An emerging role of sonic hedgehog shedding as a modulator of heparan sulfate interactionsIn: The Journal of Biological Chemistry (JBC) , Jg. 287 2012, Nr. 52, S. 43708 – 43719
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Escape from a dominant hla-b*15-restricted cd8+ t cell response against hepatitis c virus requires compensatory mutations outside the epitopeIn: Journal of Virology , Jg. 86 2012, Nr. 2, S. 991 – 1000DOI (Open Access)
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The Normal-Mode Entropy in the MM/GBSA Method : Effect of System Truncation, Buffer Region, and Dielectric ConstantIn: Journal of Chemical Information and Modeling , Jg. 52 2012, Nr. 8, S. 2079 – 2088DOI (Open Access)
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The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated proteinIn: Human Molecular Genetics , Jg. 21 2012, Nr. 18, S. 4038 – 4048DOI (Open Access)
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An additional glucose dehydrogenase from Sulfolobus solfataricus : fine-tuning of sugar degradation?In: Biochemical Society Transactions , Jg. 39 2011, Nr. 1, S. 77 – 81
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Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptidesIn: Nature Communications , Jg. 2 2011, S. 453DOI (Open Access)
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CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural ProteinsIn: Gastroenterology , Jg. 140 2011, Nr. 7, S. 2064 – 2073
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Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiersIn: BioData Mining , Jg. 4 2011, Nr. 1, S. 26DOI, Online Volltext (Open Access)
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Interpol : An R package for preprocessing of protein sequencesIn: BioData Mining , Jg. 4 2011, S. 16DOI, Online Volltext (Open Access)
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Machine learning on normalized protein sequencesIn: BMC Research Notes , Jg. 4 2011, S. 94DOI, Online Volltext (Open Access)
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Parental origin and functional relevance of a de novo UBE3A variantIn: European Journal of Medical Genetics (EJMG) , Jg. 54 2011, Nr. 1, S. 19 – 24
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Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics , Jg. 7 2011, S. 135 – 148DOI, Online Volltext (Open Access)
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Sonic hedgehog shedding results in functional activation of the solubilized proteinIn: Developmental Cell , Jg. 20 2011, Nr. 6, S. 764 – 774DOI (Open Access)
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Estimating affinities of calcium ions to proteinsIn: Advances and Applications in Bioinformatics and Chemistry , Jg. 3 2010, Nr. 1, S. 1 – 6DOI (Open Access)
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Predicting Bevirimat resistance of HIV-1 from genotypeIn: BMC Bioinformatics , Jg. 11 2010, S. 37DOI (Open Access)
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Prediction of Co-Receptor Usage of HIV-1 from GenotypeIn: PLoS Computational Biology , Jg. 6 2010, Nr. 4, S. e1000743DOI (Open Access)
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Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrateIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 107 2010, Nr. 12, S. 5522 – 5527
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Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism.In: AIDS Research and Therapy , Jg. 7 2010, S. 41DOI, Online Volltext (Open Access)
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The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitroIn: Antiviral Research , Jg. 86 2010, Nr. 3, S. 312 – 315
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Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60In: Chromosoma , Jg. 119 2010, Nr. 1, S. 99 – 113
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A novel algorithm for macromolecular epitope matchingIn: Algorithms , Jg. 2 2009, Nr. 1, S. 498 – 517
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Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patientsIn: Journal of Infection , Jg. 58 2009, Nr. 1, S. 61 – 67
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Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failureIn: Journal of Clinical Virology , Jg. 45 2009, Nr. 1, S. 34 – 38
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Biallelic loss of function of the promyelocytic leukaemia zinc finger (PLZF) gene causes severe skeletal defects and genital hypoplasiaIn: Journal of Medical Genetics (eJMG) , Jg. 45 2008, Nr. 11, S. 731 – 737
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Evolution : von der Biologie zur Mathematik und wieder zurück ; die Ergebnisse der Evolutionstheorie sind heute nicht nur Naturbeschreibung, sondern auch mathematisches WerkzeugIn: Unikate: Berichte aus Forschung und Lehre 2008, Nr. 33: Mathematik: eine lebendige Wissenschaft, S. 54 – 65DOI, Online Volltext (Open Access)
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Evolutionary Pareto-optimization of stably folding peptidesIn: BMC Bioinformatics , Jg. 9 2008, S. 109DOI (Open Access)
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The B-cell epitope of the monoclonal anti-factor VIII anti- body ESH8 characterized by peptide array analysisIn: Thrombosis and Haemostasis , Jg. 99 2008, Nr. 3, S. 634 – 637
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A multiobjective evolutionary method for the design of peptidic mimotopesIn: Journal of Computational Biology , Jg. 13 2006, Nr. 1, S. 113 – 125
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Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.In: Antiviral Therapy , Jg. 11 2006, Nr. 7, S. 879 – 887
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SearchXLinks : A program for the identification of disulfide bonds in proteins from mass spectraIn: Analytical Chemistry , Jg. 78 2006, Nr. 4, S. 1235 – 1241
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The enzyme-binding region of human GM2-activator proteinIn: The FEBS Journal , Jg. 273 2006, Nr. 5, S. 982 – 991
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Computational methods for the design of effective therapies against drug resistant HIV strainsIn: Bioinformatics , Jg. 21 2005, Nr. 21, S. 3943 – 3950DOI (Open Access)
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Estimating HIV evolutionary pathways and the genetic barrier to drug resistanceIn: Journal of Infectious Diseases , Jg. 191 2005, Nr. 11, S. 1953 – 1960DOI (Open Access)
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Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapyIn: Journal of Clinical Virology , Jg. 34 2005, Nr. 4, S. 277 – 287
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Learning multiple evolutionary pathways from cross-sectional dataIn: Journal of Computational Biology , Jg. 12 2005, Nr. 6, S. 584 – 598
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Mtreemix : A software package for learning and using mixture models of mutagenetic treesIn: Bioinformatics , Jg. 21 2005, Nr. 9, S. 2106 – 2107DOI (Open Access)
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Photoaffinity labelling of the Human GM2-activator protein Mechanistic insight into ganglioside GM2 degradationIn: EJB: the FEBS Journal , Jg. 271 2004, Nr. 3, S. 614 – 627
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Geno2pheno : Estimating phenotypic drug resistance from HIV-1 genotypesIn: Nucleic Acids Research , Jg. 31 2003, Nr. 13, S. 3850 – 3855
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Methods for optimizing antiviral combination therapiesIn: Bioinformatics , Jg. 19 2003, Nr. Suppl 1, S. i16 – i25DOI (Open Access)
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Structural modeling of ataxin-3 reveals distant homology to adaptinsIn: Proteins: Structure, Function and Genetics , Jg. 50 2003, Nr. 2, S. 355 – 370
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Tenofovir Resistance and ResensitizationIn: Antimicrobial Agents and Chemotherapy , Jg. 47 2003, Nr. 11, S. 3478 – 3484DOI (Open Access)
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Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotypeIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 99 2002, Nr. 12, S. 8271 – 8276
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Partial reduction and two-step modification of proteins for identification of disulfide bondsIn: Analytical Chemistry , Jg. 74 2002, Nr. 10, S. 2386 – 2393
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Screening for disulfide bonds in proteins by MALDI in-source decay and LIFT-TOF/TOF-MSIn: Analytical Chemistry , Jg. 74 2002, Nr. 19, S. 4980 – 4988
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Web Site : The Protein Information ResourceIn: Angewandte Chemie International Edition , Jg. 41 2002, Nr. 6, S. 1075 – 1075
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Geno2pheno : Interpreting Genotypic HIV Drug Resistance TestsIn: IEEE Intelligent Systems , Jg. 16 2001, Nr. 6, S. 35 – 41DOI, Online Volltext (Open Access)
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Neue Wege zur Optimierung von Anti-HIV-Therapien : Erste Analysen mit bioinformatischen MethodenIn: BIOforum , Jg. 24 2001, Nr. 12, S. 912 – 914
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Band-flip and kink as novel structural motifs in α-(1→4)-D-glucose oligosaccharides. Crystal structures of cyclodeca- and cyclotetradecaamyloseIn: Carbohydrate Research , Jg. 322 1999, Nr. 3-4, S. 228 – 246
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Two-Stage Method for Protein-Ligand DockinIn: (J. Med. Chem.) , Jg. 42 1999, S. 4422 – 4433
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Two-stage method for protein-ligand dockingIn: Journal of Medicinal Chemistry , Jg. 42 1999, Nr. 21, S. 4422 – 4433
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A structural role for glycosylation : Lessons from the hp modelIn: Folding and Design , Jg. 3 1998, Nr. 5, S. 337 – 343DOI (Open Access)
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A structural role for glycosylation: lessons from the hp-modeIn: Folding & Design , Jg. 3 1998, S. 337 – 343
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Strain-Induced “Band Flips” in Cyclodecaamylose and Higher HomologuesIn: Angewandte Chemie International Edition , Jg. 37 1998, Nr. 5
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Structures of the Common Cyclodextrins and Their Larger Analogues -- Beyond the DoughnuIn: Chemical Reviews , Jg. 98 1998, S. 1787 – 1802
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Structures of the common cyclodextrins and their larger analogues : beyond the doughnutIn: Chemical Reviews , Jg. 98 1998, Nr. 5, S. 1787 – 1802
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Folding Pathways of a Helix-Turn-Helix Model ProteinIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry , Jg. 101 1997, Nr. 34, S. 6734 – 6740DOI, Online Volltext (Open Access)
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Polypeptide folding with-off lattice Monte Carlo dynamics : The methodIn: European Biophysics Journal , Jg. 24 1996, Nr. 6, S. 387 – 403
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Protein dynamics with off-lattice monte carlo movesIn: Physical Review E: Statistical, nonlinear, and soft matter physics , Jg. 53 1996, Nr. 4, S. 4221 – 4224DOI, Online Volltext (Open Access)
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Ensuring fuels for DNA repair : Analysis of irradiated cancer cells reveals mitochondrial shutdownIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 197 2021, Nr. Suppl. 1, S. 200
-
Epigenetic profiling of articular chondrocytes
OARSI World Congress on Osteoarthritis, 29.04.-01.05.2021, Virtual,In: Osteoarthritis and Cartilage , Jg. 29 2021, Nr. Suppl. 1: Abstracts from the Virtual 2021 OARSI World Congress on Osteoarthritis, S. 309DOI (Open Access) -
Modeling common aspects of the metabolic response of cancer cells to ionizing radiation
AACR Annual Meeting 2021, April 10-15, 2021 and May 17-21, 2021, Philadelphia, PA, USA,In: Cancer Research , Jg. 81 2021, Nr. Suppl. 13, 3065 -
A phase 3b, open-label, pilot study to evaluate switching to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) in virologically-suppressed HIV-1 infected adult subjects harboring the NRTI resistance mutation M184V and/or M184I (GS-US-292-1824)In: Journal of the International AIDS Society , Jg. 21 2018, Nr. Suppl. 6, e25148DOI (Open Access)
-
Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B CellsIn: Scandinavian Journal of Immunology , Jg. 80 2014, Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, S. 233
-
Optimisation of baseline genotypic testing for safe and efficient maraviroc administrationIn: Journal of the International AIDS Society , Jg. 15 2012, Nr. S4, S. P165DOI (Open Access)
-
Predicting HIV-1 Cytopathogenicity and Co-Receptor Usage from V3 Envelope Sequences by Machine LearningIn: The 1st IAS Conference on HIV Pathogenesis and Treatment, July 8-11, 2001, Buenos Aires, Argentina: science leading the future : final programme and abstracts / 1st IAS Conference on HIV Pathogenesis and Treatment, 8-11 July 2001, Buenos Aires, Argentina 2001, S. 268
-
Uncertainty-aware quantitative analysis of high-throughput live cell migration data2025DOI (Open Access)
-
Arevir : A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIVIn: Data Integration in the Life Sciences / Third International Workshop (DILS), July 20-22, 2006, Hinxton, UK, / Leser, Ulf; Naumann, Felix; Eckman, Barbara (Hrsg.) 2006, S. 185 – 194
-
A multi-objective evolutionary approach to peptide structure redesign and stabilizationIn: Proceedings of the 7th annual conference on Genetic and evolutionary computation / GECCO 2005 - Genetic and Evolutionary Computation Conference, 25-29 June 2005, Washington D.C., United States / Beyer, Hans-Georg (Hrsg.) 2005, S. 423 – 429
-
Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature RankingIn: Knowledge Discovery in Databases: PKDD 2005: th European Conference on Principles and Practice of Knowledge Discovery in Databases, Porto, Portugal, October 3-7, 2005. Proceedings / 9th European Conference on Principles and Practice of Knowledge Discovery in Databases (PKDD 2005), 3-7 October 2005, Porto, Portugal / Jorge, Alípio Mário; Torgo, Luís; Brazdil, Pavel; Camacho, Rui; Gama, João (Hrsg.) 2005, S. 285 – 296
-
Computergestützte molekulare Modellierung für die Suche nach neuen Wirkstoffen gegen HIV/AIDSIn: Resistenz in der HIV-Therapie: Diagnostik und Management / Oette, Mark; Kaiser, Rolf; Häussinger, Dieter (Hrsg.) 2003, S. 62 – 65
-
A New Method for the Fast Solution of Protein-3D-Structures, combining Experiments and BioinformaticsIn: Coupling of Biological and Electronic Systems: Proceedings of the 2nd Caesarium / 2nd Caesarium, Bonn, November 1–3, 2000 / Hoffmann, Karl-Heinz (Hrsg.) 2002, S. 59 – 78
-
Identifying Drug Resistance-Associated Patterns in HIV GenotypesIn: Computer science and biology: proceedings of the German Conference on Bioinformatics / German Conference on Bioinformatics (GCB '01), 7.-10. October 2001, Braunschweig / Wingender, Edgar (Hrsg.) 2001, S. 126 – 130
-
Simulation of oligopeptide folding or how do residues talkIn: Biological Physics: Third International Symposium ; Santa Fe, NM, September 1998 / Third International Symposium on Biological Physics ; September 20-24, 1998, Santa Fe, New Mexico, USA / Frauenfelder, Hans; Hummer, Gerhard; Garcia, Roderick (Hrsg.) 1999, S. 54 – 68
-
Tackling Concrete Problems in Molecular Biophysics Using Monte Carlo and Related Methods : Glycosylation, Folding, SolvationIn: Workshop on Monte Carlo Approach to Biopolymers and Protein Folding / Workshop on Monte Carlo Approach to Biopolymers and Protein, 3 - 5 December 1997 , Jülich, Germany / Grassberger, P.; Barkema, G.; Nadler, W. (Hrsg.) 1998, S. 153 – 170
-
A Monte Carlo method for simulations of protein folding with detailed protein modelsIn: Perspectives on protein engineering: a comprehensive on-line access tool for Web-based resources, papers from Perspectives on Protein Engineering '96 / Perspectives on Protein Engineering Conference 5 (POPE5), 2-6 March 1996, Montpellier 1996
-
Monte Carlo Methoden zur Simulation der Langzeitdynamik von ProteinenBerlin: Köster 1996 (Bioinformatik)