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Biologie / ZMB / Bioinformatics & Computational Biophysics
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Universitätsstr. 2-5
45141 Essen
45141 Essen
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S03 S03 A26
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Funktionen
- Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
- Professor/in, Bioinformatik and Computational Biophysics
Aktuelle Veranstaltungen
- 2020 WS
Vergangene Veranstaltungen (max. 10)
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Epigenetic mechanisms mediating cell state transitions in chondrocytesIn: Journal of Bone and Mineral Research (JBMR) (2021) in press
ISSN: 0884-0431; 1523-4681Online Volltext: dx.doi.org/ (Open Access) -
Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axisIn: Cell Death and Disease Jg. 12 (2021) Nr. 1, S. 34
ISSN: 2041-4889Online Volltext: dx.doi.org/ (Open Access) -
Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic CellsIn: Frontiers in Immunology Jg. 11 (2021) S. 607889
ISSN: 1664-3224Online Volltext: dx.doi.org/ (Open Access) -
UMI or not UMI, that is the question for scRNA-seq zero-inflationIn: Nature Biotechnology (2021) in press
ISSN: 1087-0156; 1546-1696; 0733-222XOnline Volltext: dx.doi.org/ -
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719
ISSN: 2046-2069Online Volltext: dx.doi.org/ (Open Access) -
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719
ISSN: 2046-2069Online Volltext: dx.doi.org/ (Open Access) -
An altered heparan sulfate structure in the articular cartilage protects against osteoarthritisIn: Osteoarthritis and Cartilage Jg. 28 (2020) Nr. 7, S. 977 - 987
ISSN: 1522-9653; 1063-4584Online Volltext: dx.doi.org/ (Open Access) -
An altered heparan sulfate structure in the articular cartilage protects against osteoarthritisIn: Osteoarthritis and Cartilage (2020)
ISSN: 1063-4584; 1522-9653Online Volltext: dx.doi.org/ (Open Access) -
BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytesIn: Cancer Immunology, Immunotherapy (2020) in press
ISSN: 1432-0851; 0340-7004Online Volltext: dx.doi.org/ (Open Access) -
Bayesian Data Integration Questions Classic Study on Protease Self-Digest KineticsIn: ACS Omega Jg. 5 (2020) Nr. 25, S. 15162 - 15168
ISSN: 2470-1343Online Volltext: dx.doi.org/ (Open Access) -
Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfateIn: Matrix Biology: Journal of the International Society for Matrix Biology Jg. 39 (2020) S. 43 - 59
ISSN: 1569-1802; 0945-053XOnline Volltext: dx.doi.org/ (Open Access) -
Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19In: Frontiers in Immunology Jg. 11 (2020)
ISSN: 1664-3224Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
IgGeneUsage : differential gene usage in immune repertoiresIn: Bioinformatics (2020)
ISSN: 1367-4803; 1460-2059Online Volltext: dx.doi.org/ -
IgGeneUsage : differential gene usage in immune repertoiresIn: Bioinformatics Jg. 36 (2020) Nr. 11, S. 3590 - 3591
ISSN: 1367-4811; 1367-4803Online Volltext: dx.doi.org/ -
Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell CarcinomaIn: Clinical Cancer Research Jg. 26 (2020) Nr. 9, S. 2257 - 2267
ISSN: 1078-0432; 1557-3265Online Volltext: dx.doi.org/ -
Rapid uptake of pre-exposure prophylaxis (PrEP) after significant price reduction in Germany highlights importance of PrEP accessibilityIn: AIDS Research and Human Retroviruses (2020)
ISSN: 0889-2229; 1931-8405Online Volltext: dx.doi.org/ -
Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophyIn: Developmental Biology Jg. 457 (2020) Nr. 1, S. 104 - 118
ISSN: 0012-1606; 1095-564XOnline Volltext: dx.doi.org/ (Open Access) -
intePareto : an R package for integrative analyses of RNA-Seq and ChIP-Seq data
International Conference on Intelligent Biology and Medicine (ICIBM 2020), 9.-10.08.2020, Virtual,In: BMC Genomics Jg. 21 (2020) Nr. Supplement 11, S. 802
ISSN: 1471-2164Online Volltext: dx.doi.org/ (Open Access) -
A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism Jg. 1 (2019) Nr. 2, S. 236 - 250
ISSN: 2522-5812Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitudeIn: Chemical Communications Jg. 55 (2019) Nr. 1, S. 111 - 114
ISSN: 1364-548X; 0009-241X; 0022-4936; 1359-7345Online Volltext: dx.doi.org/ -
Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bonesIn: PLoS ONE Jg. 14 (2019) Nr. 8, S. e0218230
ISSN: 1932-6203 -
Differential escape of HCV from CD8⁺ T cell selection pressure between China and Germany depends on the presenting HLA class I moleculeIn: Journal of Viral Hepatitis Jg. 26 (2019) Nr. 1, S. 73 - 82
ISSN: 1365-2893; 1352-0504Online Volltext: dx.doi.org/ (Open Access) -
Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases Jg. 219 (2019) Nr. 3, S. 497 - 508
ISSN: 1537-6613; 0022-1899Online Volltext: dx.doi.org/ -
Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population LevelIn: Gastroenterology Jg. 156 (2019) Nr. 6, S. 1820 - 1833
ISSN: 0016-5085; 1528-0012Online Volltext: dx.doi.org/ (Open Access) -
Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly : Recent Advances and PerspectivesIn: ACS Infectious Diseases Jg. 5 (2019) Nr. 5, S. 713 - 724
ISSN: 2373-8227Online Volltext: dx.doi.org/ -
Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDVIn: Journal of Hepatology Jg. 70 (2019) Nr. Suppl. 1, S. e21
ISSN: 0168-8278Online Volltext: dx.doi.org/ -
Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cellsIn: Journal of Virology Jg. 92 (2018) Nr. 13, S. e01891 - 17
ISSN: 1098-5514; 0022-538XOnline Volltext: dx.doi.org/ -
Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood Jg. 131 (2018) Nr. 5, S. 546 - 557
ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/ (Open Access) -
Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodiesIn: Archives of Virology Jg. 163 (2018) Nr. 12, S. 3303 - 3315
ISSN: 0304-8608Online Volltext: dx.doi.org/ -
Illumina sequencing for the identification of filamentous bulking and foaming bacteria in industrial activated sludge plantsIn: International Journal of Environmental Science and Technology Jg. 15 (2018) Nr. 6, S. 1139 - 1158
ISSN: 1735-2630; 1735-1472Online Volltext: dx.doi.org/ -
Locating Large, Flexible Ligands on ProteinsIn: Journal of Chemical Information and Modeling Jg. 58 (2018) Nr. 2, S. 315 - 327
ISSN: 1549-9596; 1520-5142; 0021-9576; 0095-2338Online Volltext: dx.doi.org/ (Open Access) -
Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wingIn: eLife Jg. 7 (2018) S. e33033
ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access) -
Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter ProteinIn: ChemBioChem Jg. 19 (2018) Nr. 6, S. 591 - 595
ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/ -
Signaling systems affecting the severity of multiple osteochondromasIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 111 (2018) S. 71 - 81
ISSN: 1873-2763; 8756-3282Online Volltext: dx.doi.org/ (Open Access) -
Trade-off shapes diversity in eco-evolutionary dynamicsIn: eLife Jg. 7 (2018) S. e36273
ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access) -
Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated releaseIn: Journal of Cell Science Jg. 130 (2017) Nr. 19, S. 3261 - 3271
ISSN: 0021-9533; 1477-9137; 0370-2952Online Volltext: dx.doi.org/ (Open Access) -
Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infectionIn: Retrovirology Jg. 14 (2017) S. 42
ISSN: 1742-4690Online Volltext: dx.doi.org/ (Open Access) -
Quantitative Assessment of Molecular Dynamics Sampling for Flexible SystemsIn: Jounal of Chemical Theory and Computation Jg. 13 (2017) Nr. 2, S. 400 - 414
ISSN: 1549-9618; 1549-9626Online Volltext: dx.doi.org/ -
Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology Jg. 13 (2017) Nr. 1, S. e1005362
ISSN: 1553-734X; 1553-7358Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Role of Gag mutations in PI resistance in the Swiss HIV cohort study : bystanders or contributors?In: Journal of Antimicrobial Chemotherapy Jg. 72 (2017) Nr. 3, S. 866 - 875
ISSN: 1460-2091; 0305-7453Online Volltext: dx.doi.org/ (Open Access) -
Protistan community analysis : key findings of a large scale molecular samplingIn: ISME Journal Jg. 10 (2016) S. 2269 - 2279
ISSN: 1751-7370; 1751-7362Online Volltext: dx.doi.org/ (Open Access) -
SeqFeatR for the Discovery of Feature-Sequence AssociationsIn: PLoS ONE Jg. 11 (2016) Nr. 1, S. e0146409
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection PressureIn: Hepatology Jg. 62 (2015) Nr. 1, S. 47 - 56
ISSN: 0270-9139Online Volltext: dx.doi.org/ (Open Access) -
AmpliconDuo : a split-sample filtering protocol for high-throughput amplicon sequencing of microbial communitiesIn: PLoS ONE Jg. 10 (2015) Nr. 11, S. e0141590
ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centersIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 112 (2015) Nr. 38, S. E5281 - E5289
ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ (Open Access) -
Parameters influencing baseline HIV-1 genotypic tropism testing related to clinical outcome in patients on maravirocIn: PLoS ONE Jg. 10 (2015) Nr. 5, S. e0125502
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
Pareto optimization identifies diverse set of phosphorylation signatures predicting response to treatment with dasatinibIn: PLoS ONE Jg. 10 (2015) Nr. 6, S. e0128542
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry Jg. 36 (2015) Nr. 6, S. 2379 - 2392
ISSN: 1015-8987; 1421-9778Online Volltext: dx.doi.org/ (Open Access) -
A simple structure-based model for the prediction of HIV-1 co-receptor tropismIn: BioData Mining Jg. 7 (2014) S. 14
ISSN: 1756-0381Online Volltext: dx.doi.org/ (Open Access) -
Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'In: Virologica Sinica Jg. 29 (2014) Nr. 1, S. 40 - 47
ISSN: 1674-0769; 1995-820XOnline Volltext: dx.doi.org/ -
HLA-B*27 is protective against HCV genotype 1 and 3 and associated with targeting of distinct genotype-specific CD8(+) cell epitopesIn: Journal of Hepatology Jg. 60 (2014) Nr. Suppl. 1, S. 140
ISSN: 0168-8278Online Volltext: dx.doi.org/ -
Identification of Significant Features by the Global Mean Rank TestIn: PLoS ONE Jg. 9 (2014) Nr. 8, S. e104504
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-PeptidaseIn: PLoS Computational Biology Jg. 10 (2014) Nr. 7, S. e1003707
ISSN: 1553-7358; 1553-734XOnline Volltext: dx.doi.org/ (Open Access) -
A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 GenomesIn: PLoS ONE Jg. 8 (2013) Nr. 3, S. e58804
ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of armsIn: Organic and Biomolecular Chemistry Jg. 11 (2013) Nr. 10, S. 1631 - 1639
ISSN: 1477-0539; 1477-0520Online Volltext: dx.doi.org/ -
Correction: A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 Genomes.In: PLoS ONE Jg. 8 (2013) Nr. 12,
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE Jg. 8 (2013) Nr. 6, S. e65346
ISSN: 1932-6203Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Inference of global HIV-1 sequence patterns and preliminary feature analysisIn: Virologica Sinica Jg. 28 (2013) Nr. 4, S. 228 - 238
ISSN: 1674-0769; 1995-820XOnline Volltext: dx.doi.org/ -
Novel Algorithm for Non-Invasive Assessment of Fibrosis in NAFLDIn: PLoS ONE Jg. 8 (2013) Nr. 4, S. e62439
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovirIn: Antiviral Research Jg. 97 (2013) Nr. 2, S. 93 - 100
ISSN: 0166-3542; 1872-9096Online Volltext: dx.doi.org/ -
Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Jg. 21 (2013) Nr. 10, S. 1769 - 1777
ISSN: 1878-4186Online Volltext: dx.doi.org/ (Open Access) -
An emerging role of sonic hedgehog shedding as a modulator of heparan sulfate interactionsIn: Journal of Biological Chemistry Jg. 287 (2012) Nr. 52, S. 43708 - 43719
ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ -
Escape from a dominant hla-b*15-restricted cd8+ t cell response against hepatitis c virus requires compensatory mutations outside the epitopeIn: Journal of Virology Jg. 86 (2012) Nr. 2, S. 991 - 1000
ISSN: 0022-538X; 1098-5514Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
The Normal-Mode Entropy in the MM/GBSA Method : Effect of System Truncation, Buffer Region, and Dielectric ConstantIn: Journal of Chemical Information and Modeling Jg. 52 (2012) Nr. 8, S. 2079 - 2088
ISSN: 1549-9596; 1520-5142; 0021-9576; 0095-2338Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated proteinIn: Human Molecular Genetics Jg. 21 (2012) Nr. 18, S. 4038 - 4048
ISSN: 1460-2083; 0964-6906Online Volltext: dx.doi.org/ (Open Access) -
An additional glucose dehydrogenase from Sulfolobus solfataricus : fine-tuning of sugar degradation?In: Biochemical Society Transactions Jg. 39 (2011) Nr. 1, S. 77 - 81
ISSN: 0300-5127; 1470-8752Online Volltext: dx.doi.org/ -
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptidesIn: Nature Communications Jg. 2 (2011) S. 453
ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access) -
CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural ProteinsIn: Gastroenterology Jg. 140 (2011) Nr. 7, S. 2064 - 2073
ISSN: 0016-5085Online Volltext: dx.doi.org/ -
Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiersIn: BioData Mining Jg. 4 (2011) Nr. 1, S. 26
ISSN: 1756-0381Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Interpol : An R package for preprocessing of protein sequencesIn: BioData Mining Jg. 4 (2011) S. 16
ISSN: 1756-0381Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Machine learning on normalized protein sequencesIn: BMC Research Notes Jg. 4 (2011) S. 94
ISSN: 1756-0500Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Parental origin and functional relevance of a de novo UBE3A variantIn: European Journal of Medical Genetics Jg. 54 (2011) Nr. 1, S. 19 - 24
ISSN: 1769-7212Online Volltext: dx.doi.org/ -
Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Jg. 7 (2011) S. 135 - 148
ISSN: 1176-9343Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Sonic hedgehog shedding results in functional activation of the solubilized proteinIn: Developmental Cell Jg. 20 (2011) Nr. 6, S. 764 - 774
ISSN: 1534-5807; 1878-1551Online Volltext: dx.doi.org/ -
Estimating affinities of calcium ions to proteinsIn: Advances and Applications in Bioinformatics and Chemistry Jg. 3 (2010) Nr. 1, S. 1 - 6
ISSN: 1178-6949Online Volltext: dx.doi.org/ (Open Access) -
Predicting Bevirimat resistance of HIV-1 from genotypeIn: BMC Bioinformatics Jg. 11 (2010) S. 37
ISSN: 1471-2105Online Volltext: dx.doi.org/ (Open Access) -
Prediction of Co-Receptor Usage of HIV-1 from GenotypeIn: PLoS Computational Biology Jg. 6 (2010) Nr. 4, S. e1000743
ISSN: 1553-7358; 1553-734XOnline Volltext: dx.doi.org/ (Open Access) -
Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrateIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 107 (2010) Nr. 12, S. 5522 - 5527
ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ -
Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism.In: AIDS Research and Therapy Jg. 7 (2010) S. 41
ISSN: 1742-6405Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitroIn: Antiviral Research Jg. 86 (2010) Nr. 3, S. 312 - 315
ISSN: 1872-9096Online Volltext: dx.doi.org/ -
Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60In: Chromosoma Jg. 119 (2010) Nr. 1, S. 99 - 113
ISSN: 0009-5915; 1432-0886Online Volltext: dx.doi.org/ -
A novel algorithm for macromolecular epitope matchingIn: Algorithms Jg. 2 (2009) Nr. 1, S. 498 - 517
ISSN: 1999-4893Online Volltext: dx.doi.org/ -
Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patientsIn: Journal of Infection Jg. 58 (2009) Nr. 1, S. 61 - 67
ISSN: 0163-4453Online Volltext: dx.doi.org/ -
Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failureIn: Journal of Clinical Virology Jg. 45 (2009) Nr. 1, S. 34 - 38
ISSN: 1386-6532Online Volltext: dx.doi.org/ -
Biallelic loss of function of the promyelocytic leukaemia zinc finger (PLZF) gene causes severe skeletal defects and genital hypoplasiaIn: Journal of Medical Genetics Jg. 45 (2008) Nr. 11, S. 731 - 737
ISSN: 0022-2593; 1468-6244Online Volltext: dx.doi.org/ -
Evolution : von der Biologie zur Mathematik und wieder zurück ; die Ergebnisse der Evolutionstheorie sind heute nicht nur Naturbeschreibung, sondern auch mathematisches WerkzeugIn: Unikate: Berichte aus Forschung und Lehre (2008) Nr. 33: Mathematik: eine lebendige Wissenschaft, S. 54 - 65
ISSN: 0944-6060; 0941-746X; 1869-3881Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Evolutionary Pareto-optimization of stably folding peptidesIn: BMC Bioinformatics Jg. 9 (2008) S. 109
ISSN: 1471-2105Online Volltext: dx.doi.org/ (Open Access) -
The B-cell epitope of the monoclonal anti-factor VIII anti- body ESH8 characterized by peptide array analysisIn: Thrombosis and Haemostasis Jg. 99 (2008) Nr. 3, S. 634 - 637
ISSN: 0340-6245Online Volltext: dx.doi.org/ -
A multiobjective evolutionary method for the design of peptidic mimotopesIn: Journal of Computational Biology Jg. 13 (2006) Nr. 1, S. 113 - 125
ISSN: 1066-5277Online Volltext: dx.doi.org/ -
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.In: Antiviral Therapy Jg. 11 (2006) Nr. 7, S. 879 - 887
ISSN: 2040-2058 -
SearchXLinks : A program for the identification of disulfide bonds in proteins from mass spectraIn: Analytical Chemistry Jg. 78 (2006) Nr. 4, S. 1235 - 1241
ISSN: 0003-2700Online Volltext: dx.doi.org/ -
The enzyme-binding region of human GM2-activator proteinIn: The FEBS Journal Jg. 273 (2006) Nr. 5, S. 982 - 991
ISSN: 1742-4658; 1742-464XOnline Volltext: dx.doi.org/ -
Computational methods for the design of effective therapies against drug resistant HIV strainsIn: Bioinformatics Jg. 21 (2005) Nr. 21, S. 3943 - 3950
ISSN: 1460-2059Online Volltext: dx.doi.org/ (Open Access) -
Estimating HIV evolutionary pathways and the genetic barrier to drug resistanceIn: Journal of Infectious Diseases Jg. 191 (2005) Nr. 11, S. 1953 - 1960
ISSN: 0022-1899Online Volltext: dx.doi.org/ (Open Access) -
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapyIn: Journal of Clinical Virology Jg. 34 (2005) Nr. 4, S. 277 - 287
ISSN: 1873-5967; 1386-6532Online Volltext: dx.doi.org/ -
Learning multiple evolutionary pathways from cross-sectional dataIn: Journal of Computational Biology Jg. 12 (2005) Nr. 6, S. 584 - 598
ISSN: 1066-5277Online Volltext: dx.doi.org/ -
Mtreemix : A software package for learning and using mixture models of mutagenetic treesIn: Bioinformatics Jg. 21 (2005) Nr. 9, S. 2106 - 2107
ISSN: 1460-2059Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Photoaffinity labelling of the Human GM2-activator protein Mechanistic insight into ganglioside GM2 degradationIn: European Journal of Biochemistry: the FEBS journal Jg. 271 (2004) Nr. 3, S. 614 - 627
ISSN: 0014-2956Online Volltext: dx.doi.org/ -
Geno2pheno : Estimating phenotypic drug resistance from HIV-1 genotypesIn: Nucleic Acids Research Jg. 31 (2003) Nr. 13, S. 3850 - 3855
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ -
Methods for optimizing antiviral combination therapiesIn: Bioinformatics Jg. 19 (2003) Nr. Suppl 1,
ISSN: 1460-2059Online Volltext: dx.doi.org/ (Open Access) -
Structural modeling of ataxin-3 reveals distant homology to adaptinsIn: Proteins: Structure, Function and Genetics Jg. 50 (2003) Nr. 2, S. 355 - 370
ISSN: 0887-3585Online Volltext: dx.doi.org/ -
Tenofovir Resistance and ResensitizationIn: Antimicrobial Agents and Chemotherapy Jg. 47 (2003) Nr. 11, S. 3478 - 3484
ISSN: 0066-4804Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotypeIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 99 (2002) Nr. 12, S. 8271 - 8276
ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ -
Partial reduction and two-step modification of proteins for identification of disulfide bondsIn: Analytical Chemistry Jg. 74 (2002) Nr. 10, S. 2386 - 2393
ISSN: 0003-2700; 0096-4484; 1520-6882Online Volltext: dx.doi.org/ -
Screening for disulfide bonds in proteins by MALDI in-source decay and LIFT-TOF/TOF-MSIn: Analytical Chemistry Jg. 74 (2002) Nr. 19, S. 4980 - 4988
ISSN: 0003-2700; 0096-4484; 1520-6882Online Volltext: dx.doi.org/ -
Web Site: The Protein Information ResourceIn: Angewandte Chemie International Edition (2002)
ISSN: 1521-3773Online Volltext: dx.doi.org/ -
Geno2pheno : Interpreting Genotypic HIV Drug Resistance TestsIn: IEEE Intelligent Systems Jg. 16 (2001) Nr. 6, S. 35 - 41
ISSN: 1941-1294; 1541-1672Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Neue Wege zur Optimierung von Anti-HIV-Therapien : Erste Analysen mit bioinformatischen MethodenIn: BIOforum Jg. 24 (2001) Nr. 12, S. 912 - 914
ISSN: 0940-0079 -
Band-flip and kink as novel structural motifs in α-(1→4)-D-glucose oligosaccharides. Crystal structures of cyclodeca- and cyclotetradecaamyloseIn: Carbohydrate Research Jg. 322 (1999) Nr. 3-4, S. 228 - 246
ISSN: 0008-6215Online Volltext: dx.doi.org/ -
Simulation of oligopeptide folding or how do residues talkIn: AIP Conference Proceedings Jg. 487 (1999) Nr. 1, S. 54 - 68
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Two-Stage Method for Protein-Ligand DockinIn: (J. Med. Chem.) Jg. 42 (1999) S. 4422 - 4433
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Two-stage method for protein-ligand dockingIn: Journal of Medicinal Chemistry Jg. 42 (1999) Nr. 21, S. 4422 - 4433
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A structural role for glycosylation : Lessons from the hp modelIn: Folding and Design Jg. 3 (1998) Nr. 5, S. 337 - 343
ISSN: 1878-5808; 1359-0278Online Volltext: dx.doi.org/ (Open Access) -
A structural role for glycosylation: lessons from the hp-modeIn: Folding & Design Jg. 3 (1998) S. 337 - 343
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Strain induced flips of glucoses in cyclodecaamylose and higher homologueIn: (Angew. Chem. Int. Ed.) Jg. 37 (1998) S. 605 - 609
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Strain-Induced “Band Flips” in Cyclodecaamylose and Higher HomologuesIn: Angewandte Chemie International Edition Jg. 37 (1998) Nr. 5,
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Structures of the Common Cyclodextrins and Their Larger Analogues -- Beyond the DoughnuIn: Chemical Reviews Jg. 98 (1998) S. 1787 - 1802
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Structures of the common cyclodextrins and their larger analogues : beyond the doughnutIn: Chemical Reviews Jg. 98 (1998) Nr. 5, S. 1787 - 1802
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Folding Pathways of a Helix-Turn-Helix Model ProteinIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 101 (1997) Nr. 34, S. 6734 - 6740
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Polypeptide folding with-off lattice Monte Carlo dynamics : The methodIn: European Biophysics Journal Jg. 24 (1996) Nr. 6, S. 387 - 403
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Protein dynamics with off-lattice monte carlo movesIn: Physical Review E: Statistical, nonlinear, and soft matter physics Jg. 53 (1996) Nr. 4, S. 4221 - 4224
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Immune activation parameters are differentially expressed across four countries in sub-Saharan Africa and are associated with comorbidities in HIV plus and HIV-individualsIn: Journal of the International AIDS Society Jg. 21 (2018) Nr. S6, S. e25148
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Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B CellsIn: Scandinavian Journal of Immunology Jg. 80 (2014) Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, S. 233
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Optimisation of baseline genotypic testing for safe and efficient maraviroc administrationIn: Journal of the International AIDS Society / Eleventh International Congress on Drug Therapy in HIV Infection; 11-15 November 2012; Glasgow, UK Jg. 15 (2012) Nr. S4, S. P165
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Predicting HIV-1 Cytopathogenicity and Co-Receptor Usage from V3 Envelope Sequences by Machine LearningIn: The 1st IAS Conference on HIV Pathogenesis and Treatment, July 8-11, 2001, Buenos Aires, Argentina: science leading the future : final programme and abstracts / 1st IAS Conference on HIV Pathogenesis and Treatment, 8-11 July 2001, Buenos Aires, Argentina (2001) S. 268
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Arevir : A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIVIn: Data Integration in the Life Sciences / Third International Workshop (DILS), July 20-22, 2006, Hinxton, UK, / Leser, Ulf; Naumann, Felix; Eckman, Barbara (Hrsg.) 2006, S. 185 - 194
ISBN: 978-3-540-36593-8Online Volltext: dx.doi.org/ -
A multi-objective evolutionary approach to peptide structure redesign and stabilizationIn: Proceedings of the 7th annual conference on Genetic and evolutionary computation / GECCO 2005 - Genetic and Evolutionary Computation Conference, 25-29 June 2005, Washington D.C., United States / Beyer, Hans-Georg (Hrsg.) 2005, S. 423 - 429
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Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature RankingIn: Knowledge Discovery in Databases: PKDD 2005: th European Conference on Principles and Practice of Knowledge Discovery in Databases, Porto, Portugal, October 3-7, 2005. Proceedings / 9th European Conference on Principles and Practice of Knowledge Discovery in Databases (PKDD 2005), 3-7 October 2005, Porto, Portugal / Jorge, Alípio Mário; Torgo, Luís; Brazdil, Pavel; Camacho, Rui; Gama, João (Hrsg.) 2005, S. 285 - 296
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Computergestützte molekulare Modellierung für die Suche nach neuen Wirkstoffen gegen HIV/AIDSIn: Resistenz in der HIV-Therapie: Diagnostik und Management / Oette, Mark; Kaiser, Rolf; Häussinger, Dieter (Hrsg.) 2003, S. 62 - 65
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A New Method for the Fast Solution of Protein-3D-Structures, combining Experiments and BioinformaticsIn: Coupling of biological and electronic systems: proceedings of the 2nd caesarium, Bonn, November 1-3, 2000 / Hoffmann, K.H. (Hrsg.) 2002, S. 59 - 78
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Identifying Drug Resistance-Associated Patterns in HIV GenotypesIn: Computer science and biology: proceedings of the German Conference on Bioinformatics / German Conference on Bioinformatics (GCB '01), 7.-10. October 2001, Braunschweig / Wingender, Edgar (Hrsg.) 2001, S. 126 - 130
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Tackling Concrete Problems in Molecular Biophysics Using Monte Carlo and Related Methods : Glycosylation, Folding, SolvationIn: Workshop on Monte Carlo Approach to Biopolymers and Protein Folding / Workshop on Monte Carlo Approach to Biopolymers and Protein, 3 - 5 December 1997 , Jülich, Germany / Grassberger, P.; Barkema, G.; Nadler, W. (Hrsg.) 1998, S. 153 - 170
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Monte Carlo Methoden zur Simulation der Langzeitdynamik von Proteinen : BioinformatikBerlin (1996)
ISBN: 3-89574-150-7 -
Monte Carlo Methoden zur Simulation der Langzeitdynamik von ProteinenBerlin (1996) 115 Seiten
(Bioinformatik)ISBN: 978-3-89574-150-0