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Biologie / ZMB / Bioinformatics & Computational Biophysics
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Universitätsstr. 2-5
45141 Essen
45141 Essen
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S03 S03 A26
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Funktionen
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
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Professor/in, Bioinformatik and Computational Biophysics
Aktuelle Veranstaltungen
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2024 WS
- Current Research in Bioinformatics
- Lehramtspraktikum (LA Ma)
- Modern Biomedicine/Beispiele biologischer Forschung (Teil 1)
- Bioinformatics
- Computational Biophysics
- Anleitung zum selbstständigen wiss. Arbeiten
- Biologische Forschung mit dem Computer
- ZJD91022 Scientific Writing
- ZJD91022 Scientific Writing
Vergangene Veranstaltungen (max. 10)
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2024 SS
- Mathematical Models in Biology
- Seminar High-throughput sequencing analyses in biomedicine
- Data presentation
- High-throughput sequencing analyses in biomedicine
- Bioinformatik
- ZJD91022 Scientific Writing
- Scientific Writing
- ZJD91022 Scientific Writing
- Current Research in Bioinformatics
- Anleitung zum selbstständigen wiss. Arbeiten
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Cell-type-specific expression analysis of liver transcriptomics with clinical parameters to decipher the cause of intrahepatic inflammation in chronic hepatitis BIn: iMeta Jg. 3 (2024) Nr. 4, e221Online Volltext: dx.doi.org/ (Open Access)
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HBV shows different levels of adaptation to HLA class I-associated selection pressure correlating with markers of replicationIn: Journal of Hepatology (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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How Do Molecular Tweezers Bind to Proteins? : Lessons from X-ray CrystallographyIn: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry Jg. 29 (2024) Nr. 8, 1764Online Volltext: dx.doi.org/ (Open Access)
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Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1In: Journal of Medical Virology Jg. 96 (2024) Nr. 7, e29789Online Volltext: dx.doi.org/ (Open Access)
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Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretionIn: Nature Cardiovascular Research Jg. 3 (2024) Nr. 5, S. 525 - 540Online Volltext: dx.doi.org/ (Open Access)
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scBubbletree: computational approach for visualization of single cell RNA-seq dataIn: BMC Bioinformatics Jg. 25 (2024) Nr. 1, 302Online Volltext: dx.doi.org/ (Open Access)
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Increasing information gain in animal research by improving statistical model accuracyIn: Journal of Physics: Conference Series (JPCONF) Jg. 2514 (2023) Nr. 1, 012021Online Volltext: dx.doi.org/ (Open Access)
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Sequence diversity of hepatitis D virus in MongoliaIn: Frontiers in Medicine Jg. 10 (2023) 1108543Online Volltext: dx.doi.org/ (Open Access)
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio Jg. 14 (2023) Nr. 6, e02357-23Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinomaIn: Journal for ImmunoTherapy of Cancer Jg. 10 (2022) Nr. 1, e003198Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groupsIn: Beilstein Journal of Organic Chemistry Jg. 18 (2022) S. 1322 - 1331Online Volltext: dx.doi.org/ (Open Access)
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DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinomaIn: Oncogene Jg. 41 (2022) Nr. 1, S. 37 - 45Online Volltext: dx.doi.org/ (Open Access)
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Dissecting drivers of immune activation in chronic HIV-1 infectionIn: EBioMedicine Jg. 83 (2022) 104182Online Volltext: dx.doi.org/ (Open Access)
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances Jg. 12 (2022) Nr. 53, S. 34176 - 34184Online Volltext: dx.doi.org/ (Open Access)
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HAMdetector : A Bayesian regression model that integrates information to detect HLA-associated mutationsIn: Bioinformatics Jg. 38 (2022) Nr. 9, S. 2428 - 2436Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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Immune escape pathways from the HBV core₁₈₋₂₇ CD8 T cell response are driven by individual HLA class I allelesIn: Frontiers in Immunology Jg. 13 (2022) 1045498Online Volltext: dx.doi.org/ (Open Access)
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A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19In: Frontiers in Cellular and Infection Microbiology Jg. 11 (2021) 747816Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytesIn: Cancer Immunology, Immunotherapy Jg. 70 (2021) Nr. 6, S. 1635 - 1647Online Volltext: dx.doi.org/ (Open Access)
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Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal TransitionIn: Journal of Investigative Dermatology Jg. 141 (2021) Nr. 7, S. 1675 - 1686.e4Online Volltext: dx.doi.org/ (Open Access)
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Classifier uncertainty : Evidence, potential impact, and probabilistic treatmentIn: PeerJ Computer Science Jg. 7 (2021) S. e398Online Volltext: dx.doi.org/ (Open Access)
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Comprehensive Comparison of RNA-Seq Data of SARS-CoV-2, SARS-CoV and MERS-CoV Infections : Alternative Entry Routes and Innate Immune ResponsesIn: Frontiers in Immunology Jg. 12 (2021) 656433Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Epigenetic mechanisms mediating cell state transitions in chondrocytesIn: Journal of Bone and Mineral Research (JBMR) Jg. 36 (2021) Nr. 5, S. 968 - 985Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axisIn: Cell Death and Disease Jg. 12 (2021) Nr. 1, 34Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamicsIn: The Journal of Immunology (JI) Jg. 206 (2021) Nr. 12, S. 2839 - 2851Online Volltext: dx.doi.org/ (Open Access)
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Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic CellsIn: Frontiers in Immunology Jg. 11 (2021) S. 607889Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdownIn: iScience Jg. 24 (2021) Nr. 11, 103366Online Volltext: dx.doi.org/ (Open Access)
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Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2In: BMC Public Health Jg. 21 (2021) Nr. 1, 1178Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1505Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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UMI or not UMI, that is the question for scRNA-seq zero-inflationIn: Nature Biotechnology Jg. 39 (2021) Nr. 2, S. 158 - 159Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719Online Volltext: dx.doi.org/ (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719Online Volltext: dx.doi.org/ (Open Access)
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An altered heparan sulfate structure in the articular cartilage protects against osteoarthritisIn: Osteoarthritis and Cartilage Jg. 28 (2020) Nr. 7, S. 977 - 987Online Volltext: dx.doi.org/ (Open Access)
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Bayesian Data Integration Questions Classic Study on Protease Self-Digest KineticsIn: ACS Omega Jg. 5 (2020) Nr. 25, S. 15162 - 15168Online Volltext: dx.doi.org/ (Open Access)
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Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfateIn: Matrix Biology Jg. 39 (2020) S. 43 - 59Online Volltext: dx.doi.org/ (Open Access)
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Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19In: Frontiers in Immunology Jg. 11 (2020)Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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IgGeneUsage : differential gene usage in immune repertoiresIn: Bioinformatics Jg. 36 (2020) Nr. 11, S. 3590 - 3591Online Volltext: dx.doi.org/
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Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell CarcinomaIn: Clinical Cancer Research Jg. 26 (2020) Nr. 9, S. 2257 - 2267Online Volltext: dx.doi.org/ (Open Access)
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Rapid uptake of pre-exposure prophylaxis (PrEP) after significant price reduction in Germany highlights importance of PrEP accessibilityIn: AIDS Research and Human Retroviruses (2020)Online Volltext: dx.doi.org/
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Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophyIn: Developmental Biology Jg. 457 (2020) Nr. 1, S. 104 - 118Online Volltext: dx.doi.org/ (Open Access)
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intePareto : an R package for integrative analyses of RNA-Seq and ChIP-Seq data
International Conference on Intelligent Biology and Medicine (ICIBM 2020), 9.-10.08.2020, Virtual,In: BMC Genomics Jg. 21 (2020) Nr. Supplement 11, S. 802Online Volltext: dx.doi.org/ (Open Access) -
A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism Jg. 1 (2019) Nr. 2, S. 236 - 250Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitudeIn: Chemical Communications: ChemComm Jg. 55 (2019) Nr. 1, S. 111 - 114Online Volltext: dx.doi.org/
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Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bonesIn: PLoS ONE Jg. 14 (2019) Nr. 8, S. e0218230
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Differential escape of HCV from CD8⁺ T cell selection pressure between China and Germany depends on the presenting HLA class I moleculeIn: Journal of Viral Hepatitis Jg. 26 (2019) Nr. 1, S. 73 - 82Online Volltext: dx.doi.org/ (Open Access)
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Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases (JID) Jg. 219 (2019) Nr. 3, S. 497 - 508Online Volltext: dx.doi.org/ (Open Access)
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Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population LevelIn: Gastroenterology Jg. 156 (2019) Nr. 6, S. 1820 - 1833Online Volltext: dx.doi.org/ (Open Access)
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Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly : Recent Advances and PerspectivesIn: ACS Infectious Diseases Jg. 5 (2019) Nr. 5, S. 713 - 724Online Volltext: dx.doi.org/
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Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDVIn: Journal of Hepatology Jg. 70 (2019) Nr. Suppl. 1, S. e21Online Volltext: dx.doi.org/
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Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cellsIn: Journal of Virology Jg. 92 (2018) Nr. 13, e01891-17Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood Jg. 131 (2018) Nr. 5, S. 546 - 557Online Volltext: dx.doi.org/ (Open Access)
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Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodiesIn: Archives of Virology Jg. 163 (2018) Nr. 12, S. 3303 - 3315Online Volltext: dx.doi.org/
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Illumina sequencing for the identification of filamentous bulking and foaming bacteria in industrial activated sludge plantsIn: International Journal of Environmental Science and Technology (IJEST) Jg. 15 (2018) Nr. 6, S. 1139 - 1158Online Volltext: dx.doi.org/
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Locating Large, Flexible Ligands on ProteinsIn: Journal of Chemical Information and Modeling Jg. 58 (2018) Nr. 2, S. 315 - 327Online Volltext: dx.doi.org/ (Open Access)
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Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wingIn: eLife Jg. 7 (2018) S. e33033Online Volltext: dx.doi.org/ (Open Access)
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Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter ProteinIn: ChemBioChem Jg. 19 (2018) Nr. 6, S. 591 - 595Online Volltext: dx.doi.org/
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Signaling systems affecting the severity of multiple osteochondromasIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 111 (2018) S. 71 - 81Online Volltext: dx.doi.org/ (Open Access)
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Trade-off shapes diversity in eco-evolutionary dynamicsIn: eLife Jg. 7 (2018) S. e36273Online Volltext: dx.doi.org/ (Open Access)
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Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated releaseIn: Journal of Cell Science Jg. 130 (2017) Nr. 19, S. 3261 - 3271Online Volltext: dx.doi.org/ (Open Access)
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Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infectionIn: Retrovirology Jg. 14 (2017) 42Online Volltext: dx.doi.org/ (Open Access)
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Quantitative Assessment of Molecular Dynamics Sampling for Flexible SystemsIn: Journal of Chemical Theory and Computation Jg. 13 (2017) Nr. 2, S. 400 - 414Online Volltext: dx.doi.org/
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Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology Jg. 13 (2017) Nr. 1, e1005362Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Role of Gag mutations in PI resistance in the Swiss HIV cohort study : bystanders or contributors?In: Journal of Antimicrobial Chemotherapy Jg. 72 (2017) Nr. 3, S. 866 - 875Online Volltext: dx.doi.org/ (Open Access)
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Protistan community analysis : key findings of a large scale molecular samplingIn: ISME Journal Jg. 10 (2016) S. 2269 - 2279Online Volltext: dx.doi.org/ (Open Access)
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SeqFeatR for the Discovery of Feature-Sequence AssociationsIn: PLoS ONE Jg. 11 (2016) Nr. 1, S. e0146409Online Volltext: dx.doi.org/ (Open Access)
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Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection PressureIn: Hepatology Jg. 62 (2015) Nr. 1, S. 47 - 56Online Volltext: dx.doi.org/ (Open Access)
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AmpliconDuo : a split-sample filtering protocol for high-throughput amplicon sequencing of microbial communitiesIn: PLoS ONE Jg. 10 (2015) Nr. 11, S. e0141590Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centersIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 38, S. E5281 - E5289Online Volltext: dx.doi.org/ (Open Access)
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Parameters influencing baseline HIV-1 genotypic tropism testing related to clinical outcome in patients on maravirocIn: PLoS ONE Jg. 10 (2015) Nr. 5, S. e0125502Online Volltext: dx.doi.org/ (Open Access)
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Pareto optimization identifies diverse set of phosphorylation signatures predicting response to treatment with dasatinibIn: PLoS ONE Jg. 10 (2015) Nr. 6, S. e0128542Online Volltext: dx.doi.org/ (Open Access)
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Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry Jg. 36 (2015) Nr. 6, S. 2379 - 2392Online Volltext: dx.doi.org/ (Open Access)
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A simple structure-based model for the prediction of HIV-1 co-receptor tropismIn: BioData Mining Jg. 7 (2014) S. 14Online Volltext: dx.doi.org/ (Open Access)
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Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'In: Virologica Sinica Jg. 29 (2014) Nr. 1, S. 40 - 47Online Volltext: dx.doi.org/
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HLA-B*27 is protective against HCV genotype 1 and 3 and associated with targeting of distinct genotype-specific CD8(+) cell epitopesIn: Journal of Hepatology Jg. 60 (2014) Nr. Suppl. 1, S. 140Online Volltext: dx.doi.org/
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Identification of Significant Features by the Global Mean Rank TestIn: PLoS ONE Jg. 9 (2014) Nr. 8, S. e104504Online Volltext: dx.doi.org/ (Open Access)
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Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-PeptidaseIn: PLoS Computational Biology Jg. 10 (2014) Nr. 7, S. e1003707Online Volltext: dx.doi.org/ (Open Access)
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A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 GenomesIn: PLoS ONE Jg. 8 (2013) Nr. 3, S. e58804Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of armsIn: Organic and Biomolecular Chemistry Jg. 11 (2013) Nr. 10, S. 1631 - 1639Online Volltext: dx.doi.org/
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Correction: A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 Genomes.In: PLoS ONE Jg. 8 (2013) Nr. 12,Online Volltext: dx.doi.org/ (Open Access)
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Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE Jg. 8 (2013) Nr. 6, S. e65346Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Inference of global HIV-1 sequence patterns and preliminary feature analysisIn: Virologica Sinica Jg. 28 (2013) Nr. 4, S. 228 - 238Online Volltext: dx.doi.org/
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Novel Algorithm for Non-Invasive Assessment of Fibrosis in NAFLDIn: PLoS ONE Jg. 8 (2013) Nr. 4, S. e62439Online Volltext: dx.doi.org/ (Open Access)
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The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovirIn: Antiviral Research Jg. 97 (2013) Nr. 2, S. 93 - 100Online Volltext: dx.doi.org/
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Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Jg. 21 (2013) Nr. 10, S. 1769 - 1777Online Volltext: dx.doi.org/ (Open Access)
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An emerging role of sonic hedgehog shedding as a modulator of heparan sulfate interactionsIn: The Journal of Biological Chemistry (JBC) Jg. 287 (2012) Nr. 52, S. 43708 - 43719Online Volltext: dx.doi.org/
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Escape from a dominant hla-b*15-restricted cd8+ t cell response against hepatitis c virus requires compensatory mutations outside the epitopeIn: Journal of Virology Jg. 86 (2012) Nr. 2, S. 991 - 1000Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The Normal-Mode Entropy in the MM/GBSA Method : Effect of System Truncation, Buffer Region, and Dielectric ConstantIn: Journal of Chemical Information and Modeling Jg. 52 (2012) Nr. 8, S. 2079 - 2088Online Volltext: dx.doi.org/ (Open Access)
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The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated proteinIn: Human Molecular Genetics Jg. 21 (2012) Nr. 18, S. 4038 - 4048Online Volltext: dx.doi.org/ (Open Access)
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An additional glucose dehydrogenase from Sulfolobus solfataricus : fine-tuning of sugar degradation?In: Biochemical Society Transactions Jg. 39 (2011) Nr. 1, S. 77 - 81Online Volltext: dx.doi.org/
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Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptidesIn: Nature Communications Jg. 2 (2011) S. 453Online Volltext: dx.doi.org/ (Open Access)
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CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural ProteinsIn: Gastroenterology Jg. 140 (2011) Nr. 7, S. 2064 - 2073Online Volltext: dx.doi.org/
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Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiersIn: BioData Mining Jg. 4 (2011) Nr. 1, S. 26Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Interpol : An R package for preprocessing of protein sequencesIn: BioData Mining Jg. 4 (2011) S. 16Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Machine learning on normalized protein sequencesIn: BMC Research Notes Jg. 4 (2011) S. 94Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Parental origin and functional relevance of a de novo UBE3A variantIn: European Journal of Medical Genetics (EJMG) Jg. 54 (2011) Nr. 1, S. 19 - 24Online Volltext: dx.doi.org/
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Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Jg. 7 (2011) S. 135 - 148Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Sonic hedgehog shedding results in functional activation of the solubilized proteinIn: Developmental Cell Jg. 20 (2011) Nr. 6, S. 764 - 774Online Volltext: dx.doi.org/ (Open Access)
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Estimating affinities of calcium ions to proteinsIn: Advances and Applications in Bioinformatics and Chemistry Jg. 3 (2010) Nr. 1, S. 1 - 6Online Volltext: dx.doi.org/ (Open Access)
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Predicting Bevirimat resistance of HIV-1 from genotypeIn: BMC Bioinformatics Jg. 11 (2010) S. 37Online Volltext: dx.doi.org/ (Open Access)
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Prediction of Co-Receptor Usage of HIV-1 from GenotypeIn: PLoS Computational Biology Jg. 6 (2010) Nr. 4, S. e1000743Online Volltext: dx.doi.org/ (Open Access)
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Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrateIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 107 (2010) Nr. 12, S. 5522 - 5527Online Volltext: dx.doi.org/
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Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism.In: AIDS Research and Therapy Jg. 7 (2010) S. 41Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitroIn: Antiviral Research Jg. 86 (2010) Nr. 3, S. 312 - 315Online Volltext: dx.doi.org/
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Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60In: Chromosoma Jg. 119 (2010) Nr. 1, S. 99 - 113Online Volltext: dx.doi.org/
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A novel algorithm for macromolecular epitope matchingIn: Algorithms Jg. 2 (2009) Nr. 1, S. 498 - 517Online Volltext: dx.doi.org/
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Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patientsIn: Journal of Infection Jg. 58 (2009) Nr. 1, S. 61 - 67Online Volltext: dx.doi.org/
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Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failureIn: Journal of Clinical Virology Jg. 45 (2009) Nr. 1, S. 34 - 38Online Volltext: dx.doi.org/
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Biallelic loss of function of the promyelocytic leukaemia zinc finger (PLZF) gene causes severe skeletal defects and genital hypoplasiaIn: Journal of Medical Genetics (eJMG) Jg. 45 (2008) Nr. 11, S. 731 - 737Online Volltext: dx.doi.org/
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Evolution : von der Biologie zur Mathematik und wieder zurück ; die Ergebnisse der Evolutionstheorie sind heute nicht nur Naturbeschreibung, sondern auch mathematisches WerkzeugIn: Unikate: Berichte aus Forschung und Lehre (2008) Nr. 33: Mathematik: eine lebendige Wissenschaft, S. 54 - 65Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Evolutionary Pareto-optimization of stably folding peptidesIn: BMC Bioinformatics Jg. 9 (2008) S. 109Online Volltext: dx.doi.org/ (Open Access)
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The B-cell epitope of the monoclonal anti-factor VIII anti- body ESH8 characterized by peptide array analysisIn: Thrombosis and Haemostasis Jg. 99 (2008) Nr. 3, S. 634 - 637Online Volltext: dx.doi.org/
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A multiobjective evolutionary method for the design of peptidic mimotopesIn: Journal of Computational Biology Jg. 13 (2006) Nr. 1, S. 113 - 125Online Volltext: dx.doi.org/
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Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.In: Antiviral Therapy Jg. 11 (2006) Nr. 7, S. 879 - 887
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SearchXLinks : A program for the identification of disulfide bonds in proteins from mass spectraIn: Analytical Chemistry Jg. 78 (2006) Nr. 4, S. 1235 - 1241Online Volltext: dx.doi.org/
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The enzyme-binding region of human GM2-activator proteinIn: The FEBS Journal Jg. 273 (2006) Nr. 5, S. 982 - 991Online Volltext: dx.doi.org/
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Computational methods for the design of effective therapies against drug resistant HIV strainsIn: Bioinformatics Jg. 21 (2005) Nr. 21, S. 3943 - 3950Online Volltext: dx.doi.org/ (Open Access)
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Estimating HIV evolutionary pathways and the genetic barrier to drug resistanceIn: Journal of Infectious Diseases Jg. 191 (2005) Nr. 11, S. 1953 - 1960Online Volltext: dx.doi.org/ (Open Access)
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Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapyIn: Journal of Clinical Virology Jg. 34 (2005) Nr. 4, S. 277 - 287Online Volltext: dx.doi.org/
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Learning multiple evolutionary pathways from cross-sectional dataIn: Journal of Computational Biology Jg. 12 (2005) Nr. 6, S. 584 - 598Online Volltext: dx.doi.org/
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Mtreemix : A software package for learning and using mixture models of mutagenetic treesIn: Bioinformatics Jg. 21 (2005) Nr. 9, S. 2106 - 2107Online Volltext: dx.doi.org/ (Open Access)
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Photoaffinity labelling of the Human GM2-activator protein Mechanistic insight into ganglioside GM2 degradationIn: European Journal of Biochemistry: the FEBS journal Jg. 271 (2004) Nr. 3, S. 614 - 627Online Volltext: dx.doi.org/
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Geno2pheno : Estimating phenotypic drug resistance from HIV-1 genotypesIn: Nucleic Acids Research Jg. 31 (2003) Nr. 13, S. 3850 - 3855Online Volltext: dx.doi.org/
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Methods for optimizing antiviral combination therapiesIn: Bioinformatics Jg. 19 (2003) Nr. Suppl 1, S. i16 - i25Online Volltext: dx.doi.org/ (Open Access)
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