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Privatdozent/in, Klinik für Knochenmarktransplantation
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WiSe 2025
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SoSe 2025
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WiSe 2024
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SoSe 2024
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WiSe 2023
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SoSe 2023
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WiSe 2022
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SoSe 2022
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WiSe 2021
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SoSe 2021
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WiSe 2020
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Favorable rates of cardiovascular events with stringent cardiovascular monitoring and a lowered dose of ponatinib as second line treatment in chronic phase chronic myeloid leukemia (CML-CP) patients failing or intolerant to first-line second generation tyrosine kinase inhibitor (TKI) treatment : Results of the prospective PONS trialIn: Acta Haematologica, 2025, in press
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Cytomegalovirus immunoglobulin serology prevalence in patients with newly diagnosed multiple myeloma treated within the GMMG-MM5 phase III trialIn: Hematology, Jg. 29, 2024, Nr. 1, 2320006DOI (Open Access)
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Outcomes of CMML patients undergoing allo-HCT are significantly worse compared to MDS : A study of the CMWP of the EBMTIn: American Journal of Hematology, Jg. 99, 2024, Nr. 2, S. 203 – 215DOI (Open Access)
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General condition and comorbidity of long-term survivors of adult acute lymphoblastic leukemiaIn: Haematologica / The Hematology Journal, Jg. 108, 2023, Nr. 7, S. 1758 – 1767DOI (Open Access)
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Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of ageIn: Leukemia, Jg. 35, 2021, Nr. 3, S. 809 – 822DOI (Open Access)
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Long-term follow-up of subcutaneous versus intravenous bortezomib during induction therapy for newly diagnosed multiple myeloma treated within the GMMG-MM5 Phase III TrialIn: Leukemia, 2021
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Post-transplantation cyclophosphamide GvHD prophylaxis after hematopoietic stem cell transplantation from 9/10 or 10/10 HLA-matched unrelated donors for acute leukemiaIn: Leukemia, Jg. 35, 2021, Nr. 2, S. 585 – 594
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Prognostic impact of serum free light chain ratio normalization in patients with multiple myeloma treated within the GMMG-MM5 trialIn: Cancers, Jg. 13, 2021, Nr. 19, 4856DOI (Open Access)
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Publisher Correction : Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of ageIn: Leukemia, Jg. 35, 2021, Nr. 12, S. 3636DOI (Open Access)
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Association of Country-Specific Socioeconomic Factors With Survival of Patients Who Experience Severe Classic Acute Graft-vs.-Host Disease After Allogeneic Hematopoietic Cell Transplantation : An Analysis From the Transplant Complications Working Party of the EBMTIn: Frontiers in Immunology, Jg. 11, 2020, S. 1537DOI (Open Access)
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Response-adapted lenalidomide maintenance in newly diagnosed myeloma: results from the phase III GMMG-MM5 trialIn: Leukemia, Jg. 34, 2020, Nr. 7, S. 1853 – 1865
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Normalization of serum free light chains during therapy in the MM5 trial predicts prolonged progression free survival and overall survival
17th International Myeloma Workshop ; September 12-15, 2019, Boston, MA, USA,In: Clinical Lymphoma, Myeloma & Leukemia, Jg. 19, 2019, Nr. 10, Suppl., S. e208 -
Cytomegalovirus induces HLA-class-II-restricted alloreactivity in an acute myeloid leukemia cell lineIn: PLoS ONE, Jg. 13, 2018, Nr. 1, S. e0191482DOI, Online Volltext (Open Access)
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Early CMV replication after allogeneic stem cell transplantation is associated with a reduced relapse risk in acute myeloid leukemia : results of a prospective non-interventional trialIn: Oncology Research and Treatment, Jg. 40, 2017, Nr. Suppl. 3, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 101
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Early CMV-replication after allogeneic stem cell transplantation is associated with a reduced relapse risk in lymphomaIn: Leukemia and Lymphoma, Jg. 58, 2017, Nr. 4, S. 822 – 833
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Cytomegalovirus replication reduces the relapse incidence in patients with acute myeloid leukemiaIn: Blood, Jg. 128, 2016, Nr. 3, S. 456 – 459
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Cytomegalovirus induces apoptosis in acute leukemia cells as a virus-versus-leukemia functionIn: Leukemia and Lymphoma, Jg. 56, 2015, Nr. 11, S. 3189 – 3197
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A non-interventional study of the genetic polymorphisms of NOD2 associated with increased mortality in non-alcoholic liver transplant patientsIn: BMC Gastroenterology, Jg. 14, 2014, Nr. 1, S. 4DOI (Open Access)
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CMV and Relapse : What Has Conditioning to Do with It?In: Biology of Blood and Marrow Transplantation, Jg. 20, 2014, Nr. 1, S. 1 – 2DOI (Open Access)
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Human chorionic gonadotropin and indolamine 2,3-dioxygenase in patients with GVHDIn: Bone Marrow Transplantation, Jg. 49, 2014, Nr. 6, S. 800 – 805
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Inhibition of mTOR with everolimus and silencing by vascular endothelial cell growth factor-specific siRNA induces synergistic antitumor activity in multiple myeloma cellsIn: Cancer Gene Therapy, Jg. 21, 2014, Nr. 7, S. 275 – 282
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Additive antileukemia effects by GFI1B- and BCR-ABL-specific siRNA in advanced phase chronic myeloid leukemic cellsIn: Cancer Gene Therapy, Jg. 20, 2013, Nr. 7, S. 421 – 427
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Bronchiolitis obliterans after allogeneic hematopoietic SCT : Further insight - New perspectives?In: Bone Marrow Transplantation, Jg. 48, 2013, Nr. 9, S. 1224 – 1229
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Current practice in diagnosis and treatment of acute graft-versus-host disease : results from a survey among german-austrian-swiss hematopoietic stem cell transplant centersIn: Biology of Blood and Marrow Transplantation, Jg. 19, 2013, Nr. 5, S. 767 – 776DOI (Open Access)
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Delayed graft-versus-mast-cell effect on systemic mastocytosis with associated clonal haematological non-mast cell lineage disease after allogeneic transplantationIn: Bone Marrow Transplantation, Jg. 48, 2013, Nr. 5, S. 732 – 733
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Increased susceptibility for aspergillosis and post-transplant immune deficiency in patients with gene variants of TLR4 after stem cell transplantationIn: Transplant Infectious Disease, Jg. 15, 2013, Nr. 5, S. 533 – 539
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Influence of CEACAM expression in graft-versus-host disease after allogeneic transplantationIn: Bone Marrow Transplantation, Jg. 48, 2013, Nr. Suppl. 2, S. S179 – S180
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Long-term observation of thrombotic microangiopathies after haematopoietic stem cell transplantationIn: Bone Marrow Transplantation, Jg. 48, 2013, Nr. Suppl. 2, S. 352
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Maternal molecular features and gene profiling of monocytes during first trimester pregnancyIn: Journal of Reproductive Immunology, Jg. 99, 2013, Nr. 1-2, S. 62 – 68
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Significantly delayed T-cell immune reconstitution under mycophenolate-containing triple immunosuppressive therapy after allogeneic stem cell transplantationIn: Bone Marrow Transplantation, Jg. 48, 2013, Nr. Suppl. 2, S. S148 – S149
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Thoughts on feto-maternal tolerance : Is there a lesson to be learned from allogeneic haematopoietic stem cell transplantation?In: Cell Biology International, Jg. 37, 2013, Nr. 8, S. 766 – 767
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CMV-replication after allogeneic stem cell transplantation is associated with a GVHD-independent reduced relapse risk in lymphomaIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 156
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Clinical course and molecular features in 21 patients with atypical chronic myeloid leukemiaIn: International Journal of Laboratory Hematology, Jg. 34, 2012, Nr. 1, S. e3 – e5
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Different gene variants are associated with outcome of patients transplanted from HLA-identical unrelated donors compared to patients with sibling donorsIn: Bone Marrow Transplantation, Jg. 47, 2012, Nr. Suppl. 1, S. S165 – S166
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Dynamic international prognostic scoring system scores, pre-transplant therapy and chronic graft-versus-host disease determine outcome after allogeneic hematopoietic stem cell transplantation for myelofibrosisIn: Haematologica, the hematology journal, Jg. 97, 2012, Nr. 10, S. 1574 – 1581DOI (Open Access)
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Incidence and outcome of thrombotic microangiopathies after haematopoietic stem cell transplantationIn: Bone Marrow Transplantation, Jg. 47, 2012, Nr. Suppl. 1, S. 197
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Incidence and outcome of thrombotic microangiopathies after hematopoietic stem cell transplantationIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 211
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Incidence, mortality and biological characteristics of Bronchiolitis obliterans after allogeneic haematopoietic stem cell transplantationIn: Bone Marrow Transplantation, Jg. 47, 2012, Nr. Suppl. 1, S. 51
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Incidence, mortality and biological characteristics of bronchiolitis obliterans (BO) after allogeneic haematopoietic stem cell transplantation (HSCT)In: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 199 – 200
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Influence of CEACAMs expression in graft-versus-host disease after allogeneic transplantationIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 125
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Influence of microRNAs expression in graft-versus-host disease after allogeneic transplantationIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 92
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Jian-Jian Luan Award CMV-replication after allogeneic stem cell transplantation is associated with a GvHD-independent reduced relapse risk in lymphoma : evidence for a putative virus-versus-lymphoma effectIn: Bone Marrow Transplantation, Jg. 47, 2012, Nr. Suppl. 1, S. 60
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Only gene variants of IL10, IL23R and LCT 13910 influence transplant outcome of patients with HLA-identical unrelated donors as well as patients with sibling donorsIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 127
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Outcome of allogeneic haematopoietic stem cell transplantation in patients with atypical chronic myeloid leukaemiaIn: Bone Marrow Transplantation, Jg. 47, 2012, Nr. Suppl. 1, S. 428
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Quantitative expression of Toll-like receptor-1,-2,-3,-5,-7, and-9 in blasts of patients with newly diagnosed or relapsed acute myeloid leukaemiaIn: Bone Marrow Transplantation, Jg. 47, 2012, Nr. Suppl. 1, S. 113
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Response : T cells are required for the CMV-induced antileukemia effect after transplantIn: Blood, Jg. 119, 2012, Nr. 4, S. 1090 – 1091
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T cells are required for the CMV-induced anti-leukemic effect in patients with acute myeloid leukemia patients after transplantIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 173
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T-cells but not KIR ligand incompatibilities are required for the CMV-induced anti-leukaemic effect in patients with AML after transplantIn: Bone Marrow Transplantation, Jg. 47, 2012, Nr. Suppl. 1, S. 71
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The effect of low-energy laser therapy on oral chronic graft versus host diseaseIn: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 210
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Chronic GvHD is the most pivotal factor for improved relapse-free survival in patients with myelofibrosis after myeloablative allogeneic haematopoietic stem cell transplantationIn: Bone Marrow Transplantation, Jg. 46, 2011, Nr. Suppl. 1, S. S362 – S362
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Early CMV-replication after allogeneic stem cell transplantation is associated with a dramatically reduced relapse risk in acute myeloid leukemia patients : Evidence for a putative virus-versus-leukemia effectIn: Onkologie, Jg. 34 6, 2011, S. 297 – 297
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Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk : evidence for a putative virus-versus-leukemia effect in acute myeloid leukemia patientsIn: Blood, Jg. 118, 2011, Nr. 5, S. 1402 – 1412DOI (Open Access)
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H1N1 in allogeneic stem cell recipients : Courses of infection and influence of vaccination on graft-versus-host-disease (GVHD)In: Annals of Hematology, Jg. 90, 2011, Nr. 1, S. 117 – 118
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Increased miRNA17 and miRNA20a expression in patients with development of acute graft-versus-host disease after allogeneic stem cell transplantationIn: Bone Marrow Transplantation, Jg. 46, 2011, Nr. Suppl. 1, S. S243 – S244
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Inhibition of mTOR with everolimus (RAD001) and silencing by vascular endothelial cell growth factor specific siRNA induces additive antitumor activity in multiple myeloma cellsIn: Onkologie, Jg. 34 6, 2011, S. 163 – 163
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Modulating impact of human chorionic gonadotropin hormone on the maturation and function of hematopoietic cellsIn: Journal of Leukocyte Biology (JLB), Jg. 90, 2011, Nr. 5, S. 1017 – 1026
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Progressive Improvement in Cutaneous and Extracutaneous Chronic Graft-versus-Host Disease after a 24-Week Course of Extracorporeal Photopheresis—Results of a Crossover Randomized StudyIn: Biology of Blood and Marrow Transplantation, Jg. 17, 2011, Nr. 12, S. 1775 – 1782DOI (Open Access)
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Retrospective analysis of treosulfan-based conditioning in comparison with standard conditioning in patients with myelodysplastic syndromeIn: Bone Marrow Transplantation, Jg. 46, 2011, Nr. 4, S. 502 – 509
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Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donorsIn: Bone Marrow Transplantation, Jg. 46, 2011, Nr. 5, S. 702 – 708DOI (Open Access)
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Intraperitoneal and intrapleural application of Rituximab in refractory CD20-positive B-cell lymphoma
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie, Jg. 33, 2010, Nr. Suppl. 6, S. 253 -
No influence of gene polymorphism of LCT (C13910T) on transplantation outcomes in acute myeloid leukemia patients who received transplantations from HLA-identical sibling donorsIn: Blood, Jg. 115, 2010, Nr. 17, S. 3644 – 3645
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Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinibIn: Haematologica, the hematology journal, Jg. 95, 2010, Nr. 3, S. 388 – 397
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Biological effects of stroma-derived factor-1 alpha on normal and CML CD34+ haemopoietic cellsIn: Leukemia, Jg. 14, 2000, Nr. 9, S. 1652 – 1660
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Second-line ponatinib in chronic phase chronic myeloid leukemia (CML-CP) patients failing or intolerant to first-line second generation tyrosine kinase inhibitor (TKI) treatment : An interim analysis of the PONS trial
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 69DOI (Open Access) -
Second-Line Ponatinib in Chronic Phase Chronic Myeloid Leukemia (CML-CP) Patients Failing or Intolerant to First-Line Second Generation Tyrosine Kinase Inhibitor (TKI) Treatment : An Interim Analysis of the Prospective PONS Trial
64th ASH Annual Meeting and Exposition, 10-13 December 2022, New Orleans,In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1: 64th ASH Annual Meeting Abstracts, S. 12202 – 12203DOI (Open Access) -
Allogeneic Stem Cell Transplantation in Patients Aged ≥70 Years : Epidemiology, Outcomes, and Risk Factors Based on the German Registry for Stem Cell Transplantation (DRST)
63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 138, 2021, Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 3926 – 3928DOI (Open Access) -
Cytomegalovirus induces HLA-class-II-restricted alloreactivity in acute myeloid leukemia cell lines
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 53 – 54DOI (Open Access) -
Gene variants and miRNAs on the prediction of GvHD after allogeneic stem cell transplantation for patients with acute myeloid leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 89DOI (Open Access) -
Long-Term Survival after Transplantation in Patients with Chronic Myeloid Leukemia from HLA-Compatible Unrelated Donors: : May the Stem Cell Source Influence the Outcome?
60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 132, 2018, Nr. Supplement 1, S. 5775 – 5775DOI (Open Access) -
MiRNA expression after allogeneic stem cell transplantation
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 89DOI (Open Access) -
Early CMV-replication after allogeneic stem cell transplantation is associated with a dramatically reduced relapse risk in acute myeloid leukaemia patients : evidence for a putative virus-versus-leukaemia effectIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 46, 2011, Nr. Suppl. 1, S. S56 – S57
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Early cytomegalovirus replication after allogeneic stem cell transplantation is associated with a dramatically reduced relapse risk in acute myeloid leukemia patients : Evidence for a putative virus-versus-leukemia effectIn: Biology of Blood and Marrow Transplantation: Elsevier Health Sciences, Jg. 17, 2011, Nr. 2, Suppl., S. S161DOI (Open Access)
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Improved outcome of transplant in patients with CMLIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 46, 2011, Nr. Suppl. 1, S. 361 – 362
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Increased miRNA17 and miRNA20a expression in patients with development of acute Graft-versus-host disease after allogeneic stem cell transplantation
Deutsche, Österreichische und Schweizerische Gesellschaften für Hämatologie und Onkologie Jahrestagung, Basel, September-Oktober 2011,In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 278 -
Oxidative stress induced by small interfering RNA against glutathione reductase transcripts sensitizes mutated T315l cells to nilotinibIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 46, 2011, Nr. Suppl. 1, S. 365 – 366
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Pravastatin after allogeneic haematopoietic stem cell transplantation : better tolerated than expected but without significant influence on chronic graft-versus-host diseaseIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 46 1, 2011, Nr. Suppl. 1, S. S111 – S111
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Results of simultaneous analysis of 48 gene variants reported to have influence on transplant outcomeIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 46, 2011, Nr. Suppl. 1, S. S66 – S67
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Results of simultaneously performed analysis of 48 gene variants reported to have influence on transplant outcomeIn: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 229
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Significance of prognostic scores, risk factors and chronic graft-versus-host-disease (cGVHD) on outcome after allogeneic haematopoietic stem cell transplantation (HSCT) for myelofibrosisIn: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 206 – 206
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Clinical outcome of hepatitis B virus infection in patients receiving hematopoietic stem cell grafts from immunized donors
19th Annual Congress of the German Transplantation Society, Hamburg, Germany, 7‐9 October 2010,In: Transplant International. Lausanne: Frontiers Media, Jg. 23, 2010, Nr. Suppl. 2, S. 29 -
Cytomegalovirus increases incidence of acute GvHD and reduces the relapse risk for acute leukaemia after transplant : there is a virus-versus-leukaemia effect
EBMT (European Group for Blood and Bone Marrow Transplantation) 2010. March 21-14, 2010. Vienna, Austria,In: Bone Marrow Transplantation. London: Springer Nature, Jg. 45, 2010, Nr. Suppl. 2, S. S79 -
Genetic polymorphism of NQO1 is associated with an increased treatment-related mortality in patients undergoing allogeneic transplantationIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 45, 2010, Nr. Suppl. 2, S. S106
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Improved outcome of transplant in patients with CML
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 84 -
Influence of intestinal bacterial decontamination using ciprofloxacin plus metronidazole or moxifloxacin alone on the incidence of acute GvHD and blood stream infections after allogeneic HSCTIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 45, 2010, Nr. Suppl. 2, S. S395
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Oxidative stress induced by small interfering RNA against glutathione reductase transcripts sensitizes mutated T315I cells to nilotinib
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 142 – 143 -
TLR expression and cellular immune reconstitution in AML-patients with elevated serum ferritin levels after allogeneic transplantIn: Bone Marrow Transplantation. London: Springer Nature, Jg. 45, 2010, Nr. Suppl. 2, S. S76 – S77
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Molecular Methods Used for Detection of Minimal Residual Disease Following Hematopoietic Stem Cell Transplantation in Myeloid DisordersIn: Bone Marrow and Stem Cell Transplantation / Beksac, Meral (Hrsg.). New York: Springer, 2014, S. 187 – 207