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Prof. Dr. med. Martin Schuler

Telefon

+49 201 723 2000

Webseite

http://www.uk-essen.de/?id=2383

Funktionen

Direktor/in, Innere Klinik (Tumorforschung)

Aktuelle Veranstaltungen

2023 WS

Vergangene Veranstaltungen (max. 10)

2023 SS

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

Artikel in Zeitschriften

Kersting, David; Sandach, Patrick; Sraieb, Miriam; Wiesweg, Marcel; Metzenmacher, Martin; Darwiche, Kaid; Oezkan, Filiz; Bölükbas, Servet; Stuschke, Martin; Umutlu, Lale; Nader, Michael; Hamacher, Rainer; Fendler, Wolfgang; Wienker, Johannes; Eberhardt, Wilfried; Schuler, Martin; Herrmann, Ken; Hautzel, Hubertus

68Ga-SSO-120 PET for Initial Staging of Small Cell Lung Cancer Patients : A Single-Center Retrospective Study

In: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. 10, S. 1540 - 1549

ISSN: 1535-5667; 0161-5505; 2159-662X; 0022-3123; 0097-9058

Online Volltext: dx.doi.org/
Virchow, Isabel; Treckmann, Jürgen-Walter; Prasnikar, Nicole; Linden, Gabriele; Markus, Peter; Schumacher, Brigitte; Albers, David; Herold, Thomas; Ting, Saskia; Schmidt, Hartmut; Radunz, Sonja; Wiesweg, Marcel; Siveke, Jens; Schuler, Martin; Kasper, Stefan

A Phase II Study of Nab-Paclitaxel and Gemcitabine as First-Line Therapy in Patients with Cholangiocarcinoma Ineligible for Cisplatin-Based Chemotherapy (NACHO)

In: Oncology Research and Treatment Jg. 46 (2023) Nr. 3, S. 89 - 99

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/
Maßmann, M.; Treckmann, Jürgen Walter; Markus, P.; Schumacher, B.; Albers, D.; Ting, Saskia; Mende, B.; Roehrle, J.; Virchow, I.; Rosery, V.; Laue, K.; Zaun, G.; Kostbade, K.; Pogorzelski, M.; Schmid, Kurt Werner; Baba, Hideo Andreas; Siveke, Jens; Paul, A.; Schildhaus, Hans-Ulrich; Schuler, Martin; Wiesweg, Marcel; Kasper, Stefan

A prognostic systemic inflammation score (SIS) in patients with advanced intrahepatic cholangiocarcinoma

In: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 8, S. 5085 - 5094

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/ (Open Access)
Schmidt, Kira; Krawutschke, Marvin; Kowalski, Axel; Pasche, Saskia; Bialek, Anna; Schweig, Theresa; Weismüller, Benjamin; Tewes, Mitra; Schuler, Martin; Hamacher, Rainer; Müller, Bernhard W.; Schadendorf, Dirk; Skoda, Eva-Maria; Teufel, Martin; Fink, Madeleine

Cancer Patients’ Age-Related Benefits from Mobile Neurofeedback-Therapy in Quality of Life and Self-efficacy : A Clinical Waitlist Control Study

In: Applied Psychophysiology Biofeedback Jg. 48 (2023) Nr. 2, S. 217 - 227

ISSN: 1090-0586; 1573-3270

Online Volltext: dx.doi.org/ (Open Access)
Roehrle, Julius; Kasper, Stefan; Treckmann, Jürgen-Walter; Markus, Peter; Schumacher, Brigitte; Albers, David; Wendling, Johanna; Ting, Saskia; Mende, Bastian; Maßmann, Marlene; Markus, Maximilian; Virchow, Isabel; Rosery, Vivian; Laue, Katharina; Zaun, Gregor; Kostbade, Karina; Pogorzelski, Michael; Reissig, Timm M.; Liffers, Sven-Thorsten; Schmid, Kurt Werner; Schildhaus, Hans-Ulrich; Schuler, Martin; Siveke, Jens; Wiesweg, Marcel

Clinical Outcome and Treatment Sequences of Patients with Advanced Pancreatic Cancer Treated with Contemporary Chemotherapy Protocols

In: Oncology Research and Treatment Jg. 46 (2023) Nr. 4, S. 140 - 150

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/
Keyl, Julius; Hosch, René; Berger, Aaron; Ester, Oliver; Greiner, Tobias; Bogner, Simon; Treckmann, Jürgen; Ting, Saskia; Schumacher, Brigitte; Albers, David; Markus, Peter; Wiesweg, Marcel; Forsting, Michael; Nensa, Felix; Schuler, Martin; Kasper, Stefan; Kleesiek, Jens

Deep learning-based assessment of body composition and liver tumour burden for survival modelling in advanced colorectal cancer

In: Journal of Cachexia, Sarcopenia and Muscle Jg. 14 (2023) Nr. 1, S. 545 - 552

ISSN: 2190-6009; 2190-5991

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Sikosek, Tobias; Horos, Rastislav; Trudzinski, Franziska; Jehn, Julia; Frank, Maurice; Rajakumar, Timothy; Klotz, Laura V.; Mercaldo, Nathaniel; Kahraman, Mustafa; Heuvelman, Marco; Taha, Yasser; Gerwing, Jennifer; Skottke, Jasmin; Daniel-Moreno, Alberto; Sanchez-Delgado, Marta; Bender, Sophie; Rudolf, Christina; Hinkfoth, Franziska; Tikk, Kaja; Schenz, Judith; Weigand, Markus A.; Feindt, Peter; Schumann, Christian; Christopoulos, Petros; Winter, Hauke; Kreuter, Michael; Schneider, Marc A.; Muley, Thomas; Walterspacher, Stephan; Schuler, Martin; Darwiche, Kaid; Taube, Christian; Hegedus, Balazs; Rabe, Klaus F.; Rieger-Christ, Kimberly; Jacobsen, Francine L.; Aigner, Clemens; Reck, Martin; Bankier, Alexander A.; Sharma, Amita; Steinkraus, Bruno R.

Early Detection of Lung Cancer Using Small RNAs

In: Journal of Thoracic Oncology Jg. 18 (2023) Nr. 11, S. 1504 - 1523

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Warnecke, Eva; Salvador Comino, Maria Rosa; Kocol, Dilara; Hosters, Bernadette; Wiesweg, Marcel; Bauer, Sebastian; Welt, Anja; Heinzelmann, Anna; Müller, Sandy; Schuler, Martin; Teufel, Martin; Tewes, Mitra

Electronic Patient-Reported Outcome Measures (ePROMs) Improve the Assessment of Underrated Physical and Psychological Symptom Burden among Oncological Inpatients

In: Cancers Jg. 15 (2023) Nr. 11,

ISSN: 2072-6694

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Pant, Shubham; Schuler, Martin; Iyer, Gopa; Witt, Olaf; Doi, Toshihiko; Qin, Shukui; Tabernero, Josep; Reardon, David A.; Massard, Christophe; Minchom, Anna; Lugowska, Iwona; Carranza, Omar; Arnold, Dirk; Gutierrez, Martin; Winter, Helen; Stuyckens, Kim; Crow, Lauren; Najmi, Saltanat; Hammond, Constance; Thomas, Shibu; Santiago-Walker, Ademi; Triantos, Spyros; Sweiti, Hussein; Loriot, Yohann; Greco, Martin Alberto; Coward, Jim; Joshua, Anthony; Karapetis, Christos; Hart, Christopher; Zhang, Alison; Prenen, Hans; Goeminne, Jean-Charles; Machiels, Jean-Pascal; Rottey, Sylvie; Corassa, Marcelo; Molin, Graziela Zibetti Dal; Tiscoski, Katsuki; Jardim, Denis Leonardo Fontes; Mak, Milena; Fu, Wei; Yao, Herui; Huang, Jing; Jiang, Haiping; Chen, Baoshi; Yan, Dong; Yang, Yu; Le Tourneau, Christophe; Penel, Nicolas; Salas, Sébastien; Blay, Jean-Yves; Brachet, Pierre-Emmanuel; Durando, Xavier; Emambux, Sheik; Ravaud, Alain; Folprecht, Gunnar; Ahrens, Marit; Golf, Alexander; Haag, Georg Martin; Lordick, Florian; Desuki, Alexander; Cazzaniga, Marina; Ciardiello, Fortunato; Milella, Michele; Koyama, Takafumi; Hirooka, Yoshiki; Okamoto, Wataru; Aogi, Kenjiro; Kuboki, Yasutoshi; Lee, Jungyun; Kim, Sung-Bae; Ahn, Myung-Ju; Chang, Jong Hee; Kim, Yong-Man; Nam, Do-Hyun; Park, Jae-Sung; Paz-Ares, Luis; Moreno, Victor; Cervantes, Andres; Calvo, Mariona; Falcon, Alejandro; Gonzalez, Antonio; Martinez Bueno, Alejandro; García-Corbacho, Javier; Longo, Federico; Yen, Chia-Jui; Chen, Jen-Shi; Hou, Ming-Feng; Chao, Yee; Rau, Kun-Ming; Chiu, Tai-Jan; Feng, Yin-Hsun; Hsu, Chih-Hung; Huang, Wen-Tsung; Lai, Kuan-Ming; Yeh, Su-peng; Palmer, Daniel; Welsh, Liam; Plummer, Ruth; Iyer, Gopakumar; Bilen, Mehmet; Arrowsmith, Edward; Spigel, David Robert; Zandberg, Dan Paul; Doroshow, Deborah; Lu-Emerson, Christine; Moezi, Mehdi; Paulson, Scott; Ward, Patrick; Chaves, Jorge; Grigg, Claud; Hussein, Atif; Manda, Sudhir; Monticelli, Michael; Qamar, Rubina; Richey, Stephen L; Tamura, David; Wilks, Sharon

Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR) : An international, single-arm, phase 2 study

In: The Lancet Oncology Jg. 24 (2023) Nr. 8, S. 925 - 935

ISSN: 1474-5488; 1470-2045

Online Volltext: dx.doi.org/
Kraskowski, Oliver; Stratmann, Jan A.; Wiesweg, Marcel; Eberhardt, Wilfried; Metzenmacher, Martin; Schmid, Kurt Werner; Herold, Thomas; Schildhaus, Hans-Ulrich; Darwiche, Kaid; Aigner, Clemens; Stuschke, Martin; Laue, Katharina; Zaun, Gregor; Kasper, Stefan; Hense, Jörg; Sebastian, Martin; Schuler, Martin; Pogorzelski, Michael

Favorable survival outcomes in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer sequentially treated with a tyrosine kinase inhibitor and osimertinib in a real-world setting

In: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 11, S. 9243 - 9252

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/ (Open Access)
Rosery, Vivian; Mika, Stephan; Schmid, Kurt Werner; Reis, Henning; Stuschke, Martin; Treckmann, Jürgen; Markus, Peter; Schumacher, Brigitte; Albers, David; Mende, Bastian; Lahner, Harald; Wiesweg, Marcel; Schuler, Martin; Siveke, Jens; Kasper, Stefan

Identification of a new prognostic score for patients with high-grade metastatic GEP-NEN treated with palliative chemotherapy

In: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 8, S. 4315 - 4325

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/ (Open Access)
Zurloh, M.; Goetz, M.; Herold, T.; Treckmann, Jürgen-Walter; Markus, P.; Schumacher, B.; Albers, D.; Rink, A.; Rosery, V.; Zaun, G.; Kostbade, K.; Pogorzelski, M.; Ting, S.; Schmidt, H.; Stiens, R.; Wiesweg, Marcel; Schuler, Martin; Kasper, Stefan; Virchow, I.

Impact of encorafenib on survival of patients with BRAFV⁶⁰⁰E-mutant metastatic colorectal cancer in a real-world setting

In: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 14, S. 12903 - 12912

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/ (Open Access)
Stockhammer, Paul; Baumeister, Hannah; Ploenes, Till; Bonella, Francesco; Theegarten, Dirk; Dome, Balazs; Pirker, Christine; Berger, Walter; Hegedüs, Luca; Baranyi, Marcell; Schuler, Martin; Deshayes, Sophie; Bölükbas, Servet; Aigner, Clemens; Blanquart, Christophe; Hegedüs, Balazs

Krebs von den Lungen 6 (KL-6) is a novel diagnostic and prognostic biomarker in pleural mesothelioma

In: Lung Cancer Jg. 185 (2023)

ISSN: 1872-8332; 0169-5002

Online Volltext: dx.doi.org/
Dy, Grace K.; Govindan, Ramaswamy; Velcheti, Vamsidhar; Falchook, Gerald S.; Italiano, Antoine; Wolf, Jürgen; Sacher, Adrian G.; Takahashi, Toshiaki; Ramalingam, Suresh S.; Dooms, Christophe; Kim, Dong-Wan; Addeo, Alfredo; Desai, Jayesh; Schuler, Martin; Tomasini, Pascale; Hong, David S.; Lito, Piro; Tran, Qui; Jones, Simon; Anderson, Abraham; Hindoyan, Antreas; Snyder, Wendy; Skoulidis, Ferdinandos; Li, Bob T.

Long-Term Outcomes and Molecular Correlates of Sotorasib Efficacy in Patients With Pretreated KRAS G12C-Mutated Non-Small-Cell Lung Cancer : 2-Year Analysis of CodeBreaK 100

In: Journal of Clinical Oncology (JCO) Jg. 41 (2023) Nr. 18, S. 3311 - 3317

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Kersting, David; Mavroeidi, Ilektra-Antonia; Settelmeier, Stephan; Seifert, Robert; Schuler, Martin; Herrmann, Ken; Rassaf, Tienush; Rischpler, Christoph

Molecular Imaging Biomarkers in Cardiooncology : A View on Established Technologies and Future Perspectives

In: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. Suppl. 2, S. 29S - 38S

ISSN: 1535-5667; 0161-5505; 2159-662X; 0022-3123; 0097-9058

Online Volltext: dx.doi.org/
Fink, Madeleine; Pasche, Saskia; Schmidt, Kira; Tewes, Mitra; Schuler, Martin; Mülley, Bernhard W.; Schadendorf, Dirk; Scherbaum, Norbert; Kowalski, Axel; Skoda, Eva-Maria; Teufel, Martin

Neurofeedback Treatment Affects Affective Symptoms, But Not Perceived Cognitive Impairment in Cancer Patients : Results of an Explorative Randomized Controlled Trial

In: Integrative Cancer Therapies Jg. 22 (2023) in press

ISSN: 1552-695X; 1534-7354

Online Volltext: dx.doi.org/ (Open Access)
Grapatsas, Konstantinos; Dörr, Fabian; Menghesha, Hruy; Schuler, Martin; Grünwald, Viktor; Bauer, Sebastian; Schmidt, Hartmut H. -J.; Lang, Stephan; Kimmig, Rainer; Kasper, Stefan; Baldes, Natalie; Bölükbas, Servet

New Prognostic Score (Essen Score) to Predict Postoperative Morbidity after Resection of Lung Metastases

In: Cancers Jg. 15 (2023) Nr. 17,

ISSN: 2072-6694

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Bölükbas, Servet; Darwiche, Kaid; Theegarten, Dirk; Herrmann, Ken; Stuschke, Martin

Personalized Treatment for Patients With Lung Cancer

In: Deutsches Ärzteblatt international Jg. 120 (2023) Nr. 17, S. 300 - 310

ISSN: 1866-0452

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Sequist, Lecia V; Yang, James Chih-Hsin; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Hirsh, Vera; Mok, Tony; Geater, Sarayut Lucien; Orlov, Sergey; Tsai, Chun-Ming; Boyer, Michael; Su, Wu-Chou; Bennouna, Jaafar; Kato, Terufumi; Gorbunova, Vera; Lee, Ki Hyeong; Shah, Riyaz; Massey, Dan; Zazulina, Victoria; Shahidi, Mehdi; Schuler, Martin

Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations

In: Journal of Clinical Oncology (JCO) Jg. 41 (2023) Nr. 16, S. 2869 - 2876

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Okumus, Özlem; Mardanzai, Khaled; Plönes, Till; Theegarten, Dirk; Darwiche, Kaid; Schuler, Martin; Nensa, Felix; Hautzel, Hubertus; Hermann, Ken; Stuschke, Martin; Hegedus, Balazs; Aigner, Clemens

Preoperative PET-SUVmax and volume based PET parameters of the primary tumor fail to predict nodal upstaging in early-stage lung cancer

In: Lung Cancer Jg. 176 (2023) S. 82 - 88

ISSN: 1872-8332; 0169-5002

Online Volltext: dx.doi.org/
Maier, Daniel; Vehreschild, Jörg Janne; Uhl, Barbara; Meyer, Sandra; Berger-Thürmel, Karin; Boerries, Melanie; Braren, Rickmer; Grünwald, Viktor; Hadaschik, Boris; Palm, Stefan; Singer, Susanne; Stuschke, Martin; Juárez, David; Delpy, Pierre; Lambarki, Mohamed; Hummel, Michael; Engels, Cäcilia; Andreas, Stefanie; Gökbuget, Nicola; Ihrig, Kristina; Burock, Susen; Keune, Dietmar; Eggert, Angelika; Keilholz, Ulrich; Schulz, Hagen; Büttner, Daniel; Löck, Steffen; Krause, Mechthild; Esins, Mirko; Ressing, Frank; Schuler, Martin; Brandts, Christian; Brucker, Daniel P.; Husmann, Gabriele; Oellerich, Thomas; Metzger, Patrick; Voigt, Frederik; Illert, Anna L.; Theobald, Matthias; Kindler, Thomas; Sudhof, Ursula; Reckmann, Achim; Schwinghammer, Felix; Nasseh, Daniel; Weichert, Wilko; von Bergwelt-Baildon, Michael; Bitzer, Michael; Malek, Nisar; Öner, Öznur; Schulze-Osthoff, Klaus; Bartels, Stefan; Haier, Jörg; Ammann, Raimund; Schmidt, Anja Franziska; Guenther, Bernd; Janning, Melanie; Kasper, Bernd; Loges, Sonja; Stilgenbauer, Stephan; Kuhn, Peter; Tausch, Eugen; Runow, Silvana; Kerscher, Alexander; Neumann, Michael; Breu, Martin; Lablans, Martin; Serve, Hubert

Profile of the multicenter cohort of the German Cancer Consortium’s Clinical Communication Platform

In: European Journal of Epidemiology Jg. 38 (2023) Nr. 5, S. 573 - 586

ISSN: 0393-2990; 1573-7284

Online Volltext: dx.doi.org/ (Open Access)
Zaun, Gregor; Weber, Manuel; Metzenmacher, Martin; Wiesweg, Marcel; Hilser, Thomas; Zaun, Yasmin; Liffers, Sven; Pogorzelski, Michael; Virchow, Isabel; Eberhardt, Wilfried; Theurer, Sarah; Sabbah, Tanja Abu; Reissig, Timm M.; Stuschke, Martin; Kürten, Cornelius; Hussain, Timon; Lang, Stephan; Kasper, Stefan; Fendler, Wolfgang; Herrmann, Ken; Schuler, Martin

SUVmₐₓ Above 20 in ¹⁸F-FDG PET/CT at Initial Diagnostic Workup Associates with Favorable Survival in Patients with Cancer of Unknown Primary

In: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. 8, S. 1191 - 1194

ISSN: 1535-5667; 0161-5505; 2159-662X; 0022-3123; 0097-9058

Online Volltext: dx.doi.org/
Reissig, T.M.; Tzianopoulos, I.; Liffers, S.-T.; Rosery, V.K.; Guyot, M.; Ting, S.; Wiesweg, Marcel; Kasper, S.; Meister, P.; Herold, T.; Schmidt, H.H.; Schumacher, B.; Albers, David; Markus, P.; Treckmann, J.; Schuler, Martin; Schildhaus, Hans-Ulrich; Siveke, Jens

Smaller panel, similar results : Genomic profiling and molecularly informed therapy in pancreatic cancer

In: ESMO Open Jg. 8 (2023) Nr. 3,

ISSN: 2059-7029

Online Volltext: dx.doi.org/ (Open Access)
Strickler, John H.; Satake, Hironaga; George, Thomas J.; Yaeger, Rona; Hollebecque, Antoine; Garrido-Laguna, Ignacio; Schuler, Martin; Burns, Timothy F.; Coveler, Andrew L.; Falchook, Gerald S.; Vincent, Mark; Sunakawa, Yu; Dahan, Laetitia; Bajor, David; Rha, Sun-Young; Lemech, Charlotte; Juric, Dejan; Rehn, Marko; Ngarmchamnanrith, Gataree; Jafarinasabian, Pegah; Tran, Qui; Hong, David S.

Sotorasib in KRAS p.G12C-Mutated Advanced Pancreatic Cancer

In: The New England Journal of Medicine Jg. 388 (2023) Nr. 1, S. 33 - 43

ISSN: 1533-4406; 0028-4793

Online Volltext: dx.doi.org/
de Langen, Adrianus Johannes; Johnson, Melissa L; Mazieres, Julien; Dingemans, Anne-Marie C; Mountzios, Giannis; Pless, Miklos; Wolf, Jürgen; Schuler, Martin; Lena, Hervé; Skoulidis, Ferdinandos; Yoneshima, Yasuto; Kim, Sang-We; Linardou, Helena; Novello, Silvia; van der Wekken, Anthonie J; Chen, Yuanbin; Peters, Solange; Felip, Enriqueta; Solomon, Benjamin J; Ramalingam, Suresh S.; Dooms, Christophe; Lindsay, Colin R; Ferreira, Carlos Gil; Blais, Normand; Obiozor, Cynthia C; Wang, Yang; Mehta, Bhakti; Varrieur, Tracy; Ngarmchamnanrith, Gataree; Stollenwerk, Björn; Waterhouse, David; Paz-Ares, Luis

Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG¹²C mutation : a randomised, open-label, phase 3 trial

In: Lancet Jg. 401 (2023) Nr. 10378, S. 733 - 746

ISSN: 1474-547X; 0140-6736; 0023-7507

Online Volltext: dx.doi.org/
Hegedüs, Luca; Okumus, Özlem; Mairinger, Fabian; Ploenes, Till; Reuter, Sebastian; Schuler, Martin; Welt, Anja; Vega-Rubin-de-Celis, Silvia; Theegarten, Dirk; Bankfalvi, Agnes; Aigner, Clemens; Hegedüs, Balazs

TROP2 expression and SN38 antitumor activity in malignant pleural mesothelioma cells provide a rationale for antibody-drug conjugate therapy

In: Lung Cancer Jg. 178 (2023) S. 237 - 246

ISSN: 1872-8332; 0169-5002

Online Volltext: dx.doi.org/
Martens, Uwe M.; Schröder, Jan; Bengsch, Fee; Sellmann, Ludger; Busies, Sabine; Frank-Gleich, Stefanie; Zaiss, Matthias; Decker, Thomas; Schneeweiss, Andreas; Schuler, Martin; Grebhardt, Sina; Zacharias, Stefan; Marschner, Norbert; Kasenda, Benjamin; Potthoff, Karin; Vannier, Corinne

The INFINITY study protocol : A retrospective cohort study on decision making and clinical impact of biomarker-driven precision oncology in routine clinical practice

In: BMC Cancer Jg. 23 (2023) Nr. 1,

ISSN: 1471-2407

Online Volltext: dx.doi.org/ (Open Access)
Biersching, T.; Schweda, A.; Oechsle, K.; Nauck, F.; Schuler, U.; Hense, Jörg; Weber, M.; Junghanss, C.; Kramer, T.; Ostgathe, C.; Thuss-Patience, P.; Van Oorschot, B.; Teufel, Martin; Schuler, Martin; Bausewein, C.; Tewes, Mitra; Gahr, S.; Berendt, J.; Benze, G.; Rosenbruch, J.; Neukirchen, M.; Schwarz, J.; Reinholz, U.; Roch, C.

The OUTREACH study: Oncologists of German university hospitals in rotation on a palliative care unit : Evaluation of attitude and competence in palliative care and hospice

In: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 7, S. 2929 - 2936

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/ (Open Access)
Kessler, Lukas; Ferdinandus, Justin; Hirmas, Nader; Bauer, Sebastian; Dirksen, Uta; Zarrad, Fadi; Nader, Michael; Chodyla, Michal; Milosevic, Aleksandar; Umutlu, Lale; Schuler, Martin; Podleska, Lars; Schildhaus, Hans-Ulrich; Fendler, Wolfgang; Hamacher, Rainer; Chodyla, Michal-Kamil

68Ga-FAPI as a Diagnostic Tool in Sarcoma : Data from the 68Ga-FAPI PET Prospective Observational Trial

In: Journal of Nuclear Medicine (JNM) Jg. 63 (2022) Nr. 1, S. 89 - 95

ISSN: 1535-5667; 0161-5505; 2159-662X; 0022-3123; 0097-9058

Online Volltext: dx.doi.org/ (Open Access)
Chan, Stephen L.; Schuler, Martin; Kang, Yoon-Koo; Yen, Chia-Jui; Edeline, Julien; Choo, Su Pin; Lin, Chia-Chi; Okusaka, Takuji; Weiss, Karl-Heinz; Macarulla, Teresa; Cattan, Stéphane; Blanc, Jean-Frederic; Lee, Kyung-Hun; Maur, Michela; Pant, Shubham; Kudo, Masatoshi; Assenat, Eric; Zhu, Andrew X.; Yau, Thomas; Lim, Ho Yeong; Bruix, Jordi; Geier, Andreas; Guillén-Ponce, Carmen; Fasolo, Angelica; Finn, Richard S.; Fan, Jia; Vogel, Arndt; Qin, Shukui; Riester, Markus; Katsanou, Vasiliki; Chaudhari, Monica; Kakizume, Tomoyuki; Gu, Yi; Porta, Diana Graus; Myers, Andrea; Delord, Jean-Pierre

A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors

In: Journal of Experimental & Clinical Cancer Research Jg. 41 (2022) Nr. 1,

ISSN: 1756-9966; 0392-9078

Online Volltext: dx.doi.org/ (Open Access)
Yang, James Chih-Hsin; Schuler, Martin; Popat, Sanjay; Miura, Satoru; Park, Keunchil; Passaro, Antonio; De Marinis, Filippo; Solca, Flavio; Märten, Angela; Kim, Edward S.

Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations : An Updated Database of 1023 Cases Brief Report

In: Frontiers in Oncology Jg. 12 (2022)

ISSN: 2234-943X

Online Volltext: dx.doi.org/ (Open Access)
Metzenmacher, Martin; Hegedüs, Balazs; Forster, Jan; Schramm, Alexander; Horn, Peter; Klein, Christoph A.; Bielefeld, Nicola; Ploenes, Till; Aigner, Clemens; Theegarten, Dirk; Schildhaus, Hans-Ulrich; Siveke, Jens; Schuler, Martin; Lueong, Smiths S.

Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer

In: Translational Oncology Jg. 15 (2022) Nr. 1,

ISSN: 1936-5233; 1944-7124

Online Volltext: dx.doi.org/ (Open Access)
Wessolly, Michael; Stephan-Falkenau, Susann; Streubel, Anna; Wiesweg, Marcel; Borchert, Sabrina; Mairinger, Elena; Kollmeier, Jens; Reis, Henning; Bauer, Torsten; Schmid, Kurt Werner; Mairinger, Thomas; Schuler, Martin; Mairinger, Fabian D.

Digital gene expression analysis of NSCLC-patients reveals strong immune pressure, resulting in an immune escape under immunotherapy

In: BMC Cancer Jg. 22 (2022) Nr. 1,

ISSN: 1471-2407

Online Volltext: dx.doi.org/ (Open Access)
Guberina, Maja; Guberina, Nika; Pöttgen, Christoph; Gauler, Thomas; Richlitzki, Cedric; Metzenmacher, Martin; Wiesweg, Marcel; Plönes, Till; Forsting, Michael; Wetter, Axel; Herrmann, Ken; Hautzel, Hubertus; Darwiche, Kaid; Theegarten, Dirk; Aigner, Clemens; Schuler, Martin; Stuschke, Martin; Eberhardt, Wilfried

Effectiveness of durvalumab consolidation in stage III non-small-cell lung cancer : focus on treatment selection and prognostic factors

In: Immunotherapy Jg. 14 (2022) Nr. 12, S. 927 - 944

ISSN: 1750-743X; 1750-7448

Online Volltext: dx.doi.org/ (Open Access)
Ferdinandus, Justin; Costa, Pedro Fragoso; Kessler, Lukas; Weber, Manuel; Hirmas, Nader; Kostbade, Karina; Bauer, Sebastian; Schuler, Martin; Ahrens, Marit; Schildhaus, Hans-Ulrich; Rischpler, Christoph; Grafe, Hong; Siveke, Jens; Herrmann, Ken; Fendler, Wolfgang; Hamacher, Rainer

Initial Clinical Experience with ⁹⁰Y-FAPI-46 Radioligand Therapy for Advanced-Stage Solid Tumors : A Case Series of 9 Patients

In: Journal of Nuclear Medicine (JNM) Jg. 63 (2022) Nr. 5, S. 727 - 734

ISSN: 1535-5667; 0161-5505; 2159-662X; 0022-3123; 0097-9058

Online Volltext: dx.doi.org/ (Open Access)
Guberina, Nika; Pöttgen, Christoph; Schuler, Martin; Guberina, Maja; Stamatis, Georgios; Plönes, Till; Metzenmacher, Martin; Theegarten, Dirk; Gauler, Thomas; Darwiche, Kaid; Aigner, Clemens; Eberhardt, Wilfried; Stuschke, Martin

Long-term survival of patients with central or > 7 cm T4 N0/1 M0 non-small-cell lung cancer treated with definitive concurrent radiochemotherapy in comparison to trimodality treatment

In: Radiation Oncology Jg. 17 (2022) Nr. 1,

ISSN: 1748-717X

Online Volltext: dx.doi.org/ (Open Access)
Keyl, J.; Kasper, S.; Wiesweg, Marcel; Götze, J.; Schönrock, M.; Sinn, M.; Berger, A.; Nasca, E.; Kostbade, K.; Schumacher, B.; Markus, P.; Treckmann, Jürgen-Walter; Schmid, Kurt Werner; Schildhaus, Hans-Ulrich; Siveke, Jens; Schuler, Martin; Kleesiek, J.

Multimodal survival prediction in advanced pancreatic cancer using machine learning

In: ESMO Open Jg. 7 (2022) Nr. 5,

ISSN: 2059-7029

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Chwallek, Daniel; Schweda, Adam; Neukirchen, M.; Hense, Jörg; Schwartz, J.; Mallmann, Bernhard; Teufel, Martin; Schuler, Martin; Tewes, Mitra

PARPACT – Paramedic Palliative Care Test : Validierung eines Tests für palliatives Wissen und Selbstwirksamkeitserwartung bei Mitarbeiter*innen im Rettungswesen

In: Der Schmerz Jg. 36 (2022) Nr. 5, S. 333 - 341

ISSN: 1432-2129; 0932-433X

Online Volltext: dx.doi.org/ (Open Access)
Müller, S.; Fink, M.; Hense, Jörg; Comino, M. R. Salvador; Schuler, M.; Teufel, Martin; Tewes, Mitra

Palliative care outpatients in a German comprehensive cancer center : identifying indicators for early and late referral

In: BMC Palliative Care Jg. 21 (2022) Nr. 1,

ISSN: 1472-684X

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Subbiah, Vivek; Cassier, Philippe A.; Siena, Salvatore; Garralda, Elena; Paz-Ares, Luis; Garrido, Pilar; Nadal, Ernest; Vuky, Jacqueline; Lopes, Gilberto; Kalemkerian, Gregory P.; Bowles, Daniel W.; Seetharam, Mahesh; Chang, Jianhua; Zhang, Hui; Green, Jennifer; Zalutskaya, Alena; Schuler, Martin; Fan, Yun; Curigliano, Giuseppe

Pan-cancer efficacy of pralsetinib in patients with RET fusion–positive solid tumors from the phase 1/2 ARROW trial

In: Nature Medicine Jg. 28 (2022) Nr. 8, S. 1640 - 1645

ISSN: 1546-170X; 1078-8956

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Zimmer, Lisa; Kim, Kevin B.; Sosman, Jeffrey A.; Ascierto, Paolo A.; Postow, Michael A.; De Vos, Filip Y.F.L.; van Herpen, Carla M.L.; Carlino, Matteo S.; Johnson, Douglas B.; Berking, Carola; Reddy, Micaela B.; Harney, Allison S.; Berlin, Jordan D.; Amaria, Rodabe N.

Phase Ib/II Trial of Ribociclib in Combination with Binimetinib in Patients with NRAS-mutant Melanoma

In: Clinical Cancer Research Jg. 28 (2022) Nr. 14, S. 3002 - 3010

ISSN: 1557-3265; 1078-0432

Online Volltext: dx.doi.org/ (Open Access)
Krebs, Matthew G.; Malapelle, Umberto; André, Fabrice; Paz-Ares, Luis; Schuler, Martin; Thomas, David M.; Vainer, Gilad; Yoshino, Takayuki; Rolfo, Christian

Practical Considerations for the Use of Circulating Tumor DNA in the Treatment of Patients With Cancer

In: JAMA Oncology Jg. 8 (2022) Nr. 12, S. 1830 - 1839

ISSN: 2374-2445; 2374-2437

Online Volltext: dx.doi.org/
Guberina, Maja; Herrmann, Ken; Pöttgen, Christoph; Guberina, Nika; Hautzel, Hubertus; Gauler, Thomas; Ploenes, Till; Umutlu, Lale; Wetter, Axel; Theegarten, Dirk; Aigner, Clemens; Eberhardt, Wilfried; Metzenmacher, Martin; Wiesweg, Marcel; Schuler, Martin; Karpf-Wissel, Rüdiger; Santiago Garcia, Alina; Darwiche, Kaid; Stuschke, Martin

Prediction of malignant lymph nodes in NSCLC by machine-learning classifiers using EBUS-TBNA and PET/CT

In: Scientific Reports Jg. 12 (2022) Nr. 1,

ISSN: 2045-2322

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Scheffler, Matthias; Wiesweg, Marcel; Michels, Sebastian; Nogová, Lucia; Kron, Anna; Herold, Thomas; Scheel, Andreas H.; Metzenmacher, Martin; Eberhardt, Wilfried; Reis, Henning; Fassunke, Jana; Darwiche, Kaid; Aigner, Clemens; Schaufler, Diana; Riedel, Richard; Fischer, Rieke; Koleczko, Sophia; Schildhaus, Hans-Ulrich; Merkelbach-Bruse, Sabine; Schmid, Kurt Werner; Büttner, Reinhard; Wolf, Jürgen; Schuler, Martin

Rebiopsy in advanced non-small cell lung cancer, clinical relevance and prognostic implications

In: Lung Cancer Jg. 168 (2022) S. 10 - 20

ISSN: 1872-8332; 0169-5002

Online Volltext: dx.doi.org/
Fendler, Wolfgang; Pabst, Kim M.; Kessler, Lukas; Fragoso Costa, Pedro; Ferdinandus, Justin; Weber, Manuel; Lippert, Maria; Lückerath, Katharina; Umutlu, Lale; Kostbade, Karina; Mavroeidi, Ilektra A.; Schuler, Martin; Ahrens, Marit; Rischpler, Christoph; Bauer, Sebastian; Herrmann, Ken; Siveke, Jens; Hamacher, Rainer

Safety and Efficacy of 90Y-FAPI-46 Radioligand Therapy in Patients with Advanced Sarcoma and Other Cancer Entities

In: Clinical Cancer Research Jg. 28 (2022) Nr. 19, S. 4346 - 4353

ISSN: 1557-3265; 1078-0432

Online Volltext: dx.doi.org/ (Open Access)
Thumser-Henner, Clotilde; Oeck, Sebastian; Kalmbach, Sophie; Forster, Jan; Kindl, Franziska; Sak, Ali; Schramm, Alexander; Schuler, Martin

Syntaxin 18 regulates the DNA damage response and epithelial-to-mesenchymal transition to promote radiation resistance of lung cancer

In: Cell Death and Disease Jg. 13 (2022) Nr. 6,

ISSN: 2041-4889

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Metzenmacher, Martin; Hegedüs, Balazs; Forster, Jan; Schramm, Alexander; Horn, Peter; Klein, Christoph A.; Bielefeld, Nicola; Ploenes, Till; Aigner, Clemens; Siveke, Jens; Schuler, Martin; Lueong, Smiths S.

The clinical utility of cfRNA for disease detection and surveillance : A proof of concept study in non-small cell lung cancer

In: Thoracic Cancer (2022) in press

ISSN: 1759-7714; 1759-7706

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Wiesweg, Marcel; Eberhardt, Wilfried; Schuler, Martin; Plönes, Till

Therapie früher und lokal fortgeschrittener Stadien des nicht-kleinzelligen Lungenkarzinoms

In: Die Innere Medizin Jg. 63 (2022) Nr. 7, S. 717 - 723

ISSN: 2731-7080; 2731-7099

Online Volltext: dx.doi.org/
Peuker, Caroline A.; Yaghobramzi, Sarvenaz; Grunert, Corinna; Keilholz, Luisa; Gjerga, Enio; Hennig, Steffen; Schaper, Sigrid; Na, Il-Kang; Keller, Ulrich; Brucker, Sara; Decker, Thomas; Fasching, Peter; Fehm, Tanja; Janni, Wolfgang; Kümmel, Sherko; Schneeweiss, Andreas; Schuler, Martin; Lüftner, Diana; Busse, Antonia

Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer : findings from the RIBECCA trial

In: European Journal of Cancer (EJC) Jg. 162 (2022) S. 45 - 55

ISSN: 1879-0852; 0959-8049; 1879-2995

Online Volltext: dx.doi.org/
Metzenmacher, Martin; Kopp, Hans-Georg; Griesinger, Frank; Reinmuth, Niels; Sebastian, Martin; Serke, Monika; Waller, Cornelius Florian; Thomas, Michael; Eggert, Jochen; Schmid-Bindert, Gerald; Hoiczyk, Mathias; Christoph, Daniel; Kimmich, Martin; Deuß, Burkhard; Seifert, Stephanie; Held, Swantje; Schuler, Martin; Herold, Thomas; Breitenbücher, Frank; Eberhardt, Wilfried

A randomized, multicenter phase II study comparing efficacy, safety and tolerability of two dosing regimens of cisplatin and pemetrexed in patients with advanced or metastatic non-small-cell lung cancer

In: Therapeutic Advances in Medical Oncology Jg. 13 (2021)

ISSN: 1758-8359; 1758-8340

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Metzenmacher, Martin; Goetz, Moritz; Herold, Thomas; Stuschke, Martin; Aigner, Clemens; Darwiche, Kaid; Eberhardt, Wilfried; Schuler, Martin; Wiesweg, Marcel

Acquired Resistance to BRAF/MEK Inhibitor Therapy in BRAF-V⁶⁰⁰-mutated Squamous Cell Lung Cancer : Concurrent Evolvement of PTEN and MEK1 Mutations

In: Clinical Lung Cancer Jg. 22 (2021) Nr. 5, S. E668 - E672

ISSN: 1938-0690; 1525-7304

Online Volltext: dx.doi.org/
Rosery, Vivian; Reis, Henning; Savvatakis, Konstantinos; Kowall, Bernd; Stuschke, Martin; Paul, Andreas; Dechene, Alexander; Yang, JiaJin; Zhao, Ben; Borgers, Arianna; Kasper, Stefan; Schuler, Martin; Cheung, Phyllis F.; Siveke, Jens

Antitumor immune response is associated with favorable survival in GEP-NEN G3

In: Endocrine-Related Cancer Jg. 28 (2021) Nr. 10, S. 683 - 693

ISSN: 1351-0088; 1479-6821

Online Volltext: dx.doi.org/
Mrotzek, Simone M.; Lena, Alessia; Hadzibegovic, Sara; Ludwig, Ria; Al-Rashid, Fadi; Mahabadi, Amir Abbas; Mincu, Raluca I.; Michel, Lars; Johannsen, Laura; Hinrichs, Lena; Schuler, Martin; Keller, Ulrich; Anker, Stefan D.; Landmesser, Ulf; Rassaf, Tienush; Anker, Markus S.; Totzeck, Matthias

Assessment of coronary artery disease during hospitalization for cancer treatment

In: Clinical Research in Cardiology Jg. 110 (2021) Nr. 2, S. 200 - 210

ISSN: 1861-0692; 1861-0684

Online Volltext: dx.doi.org/ (Open Access)
Wiesweg, Marcel; Preuß, Cedric; Roeper, Julia; Metzenmacher, Martin; Eberhardt, Wilfried; Stropiep, Ursula; Wedeken, Katrin; Reis, Henning; Herold, Thomas; Darwiche, Kaid; Aigner, Clemens; Stuschke, Martin; Schildhaus, Hans-Ulrich; Schmid, Kurt Werner; Falk, Markus; Heukamp, Lukas; Tiemann, Markus; Griesinger, Frank; Schuler, Martin

BRAF mutations and BRAF mutation functional class have no negative impact on the clinical outcome of advanced NSCLC and associate with susceptibility to immunotherapy

In: European Journal of Cancer (EJC) Jg. 149 (2021) S. 211 - 221

ISSN: 1879-0852; 0959-8049; 1879-2995

Online Volltext: dx.doi.org/
Frikkel, Johanna; Beckmann, Mingo B.; de Lazzari, Nico; Götte, Miriam; Kasper, Stefan; Hense, Jörg; Schuler, Martin; Teufel, Martin; Tewes, Mitra

Changes in fatigue, barriers, and predictors towards physical activity in advanced cancer patients over a period of 12 months : A comparative study

In: Supportive Care in Cancer Jg. 29 (2021) Nr. 9, S. 5127 - 5137

ISSN: 1433-7339; 0941-4355

Online Volltext: dx.doi.org/ (Open Access)
Markus, M.; Abendroth, Annalena; Noureddine, R.; Paul, Andreas; Breitenbuecher, Sandra; Virchow, Isabel; Schmid, Kurt Werner; Markus, Peter; Schumacher, Brigitte M.; Wiesweg, Marcel; Wendling, Johanna; Mende, Bastian; Siveke, Jens; Schuler, Martin; Kasper, Stefan

Combined systemic inflammation score (SIS) correlates with prognosis in patients with advanced pancreatic cancer receiving palliative chemotherapy

In: Journal of Cancer Research and Clinical Oncology Jg. 147 (2021) Nr. 2, S. 579 - 591

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/ (Open Access)
Guberina, Maja; Sak, Ali; Pöttgen, Christoph; Tinhofer-Keilholz, Ingeborg; Budach, Volker; Balermpas, Panagiotis; Von der Grün, Jens; Rödel, Claus Michael; Gkika, Eleni; Grosu, Anca-Ligia; Abdollahi, Amir; Debus, Jürgen; Belka, Claus; Pigorsch, Steffi; Combs, Stephanie E.; Mönnich, David; Zips, Daniel; De-Colle, Chiara; Welz, Stefan; Linge, Annett; Lohaus, Fabian; Baretton, Gustavo; Gauler, Thomas; Baumann, Michael; Krause, Mechthild; Schuler, Martin; Bankfalvi, Agnes; Höing, Benedikt; Lang, Stephan; Stuschke, Martin

Correction: ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy

In: The Pharmacogenomics Journal Jg. 21 (2021) Nr. 2, S. 273

ISSN: 1470-269X; 1473-1150

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin

Corrigendum to “Inhibiting fibroblast growth factor receptors in cancer – The next generation”

In: Annals of Oncology Jg. 32 (2021) Nr. 1, S. 126

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Guberina, Maja; Sak, Ali; Pöttgen, Christoph; Tinhofer-Keilholz, Ingeborg; Budach, Volker; Balermpas, Panagiotis; Von der Grün, Jens; Rödel, Claus Michael; Gikka, Eleni; Grosu, Anca-Ligia; Abdollahi, Amir; Debus, Jürgen; Belka, Claus; Pigorsch, Steffi; Combs, Stephanie; Mönnich, David; Zips, Daniel; De-Colle, Chiara; Welz, Stefan; Linge, Annett; Lohaus, Fabian; Baretton, Gustavo; Gauler, Thomas; Baumann, Michael; Krause, Mechthild; Schuler, Martin; Bankfalvi, Agnes; Höing, Benedikt; Lang, Stephan; Stuschke, Martin

ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy

In: The Pharmacogenomics Journal Jg. 21 (2021) Nr. 1, S. 37 - 46

ISSN: 1470-269X; 1473-1150

Online Volltext: dx.doi.org/ (Open Access)
Şahin, Uǧur; Türeci, Özlem; Manikhas, Georgiy Moiseevich; Lordick, Florian; Rusyn, Andrii; Vynnychenko, Ihor A.; Dudov, Asen; Bazin, Igor S.; Bondarenko, Igor; Melichar, Bohuslav; Dhaene, Karl F.L.; Wiechen, Kai; Huber, Claudia; Maurus, Daniel; Arozullah, A.; Park, J.W.; Schuler, Martin; Al-Batran, Salah Eddin

FAST : a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma

In: Annals of Oncology Jg. 32 (2021) Nr. 5, S. 609 - 619

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Adamczyk, Alexandra; Pastille, Eva; Kehrmann, Jan; Vu, Vivian P.; Geffers, Robert; Wasmer, Marie-Hélène; Kasper, Stefan; Schuler, Martin; Lange, Christian; Muggli, Beat; Rau, Tilman T.; Klein, Diana; Hansen, Wiebke; Krebs, Philippe; Buer, Jan; Westendorf, Astrid

GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer

In: Cancer Research Jg. 81 (2021) Nr. 11, S. 2970 - 2982

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
Ho, Cassandra S. L.; Tüns, Alicia I.; Schildhaus, Hans-Ulrich; Wiesweg, Marcel; Grüner, Barbara M.; Hegedus, Balazs; Schuler, Martin; Schramm, Alexander; Oeck, Sebastian

HER2 mediates clinical resistance to the KRASG¹²C inhibitor sotorasib, which is overcome by co-targeting SHP2

In: European Journal of Cancer (EJC) Jg. 159 (2021) S. 16 - 23

ISSN: 1879-0852; 0959-8049; 1879-2995

Online Volltext: dx.doi.org/
Pogorzelski, Michael; Hilser, Thomas; Ting, Saskia; Kansy, Benjamin; Gauler, Thomas; Stuschke, Martin; Schmid, Kurt Werner; Lang, Stephan; Grünwald, Viktor; Schuler, Martin; Kasper, Stefan

Identification of a Prognostic Clinical Score for Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Treated With Systemic Therapy Including Cetuximab

In: Frontiers in Oncology Jg. 11 (2021)

ISSN: 2234-943X

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Guberina, Maja; Darwiche, Kaid; Hautzel, Hubertus; Ploenes, Till; Pöttgen, Christoph; Guberina, Nika; Herrmann, Ken; Umutlu, Lale; Wetter, Axel; Theegarten, Dirk; Aigner, Clemens; Eberhardt, Wilfried; Schuler, Martin; Karpf-Wissel, Rüdiger; Stuschke, Martin

Impact of EBUS-TBNA in addition to [¹⁸F]FDG-PET/CT imaging on target volume definition for radiochemotherapy in stage III NSCLC

In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 48 (2021) S. 2894 - 2903

ISSN: 1619-7089; 1619-7070; 0340-6997; 1432-105X

Online Volltext: dx.doi.org/ (Open Access)
Stefani, Dirk; Plönes, Till; Viehof, Jan; Darwiche, Kaid; Stuschke, Martin; Schuler, Martin; Aigner, Clemens

Lung Cancer Surgery after Neoadjuvant Immunotherapy

In: Cancers Jg. 13 (2021) Nr. 16,

ISSN: 2072-6694

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Chih-Hsin Yang, J.; Schuler, Martin; Popat, S.; Miura, S.; Heeke, S.; Passaro, A.; de Marinis, F.; Park, K.; Kim, E.S.

MO01.36 Afatinib in Asian and Non-Asian Patients (pts) with EGFR Mutation-Positive (EGFRm+) NSCLC Harboring Major Uncommon Mutations

In: Journal of Thoracic Oncology Jg. 16 (2021) Nr. 1, S. 31

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Hautzel, Hubertus; Alnajdawi, Yazan; Fendler, Wolfgang; Rischpler, Christoph; Darwiche, Kaid; Eberhardt, Wilfried; Umutlu, Lale; Theegarten, Dirk; Stuschke, Martin; Schuler, Martin; Aigner, Clemens; Herrmann, Ken; Plönes, Till

N-staging in large cell neuroendocrine carcinoma of the lung : diagnostic value of [¹⁸F]FDG PET/CT compared to the histopathology reference standard

In: EJNMMI Research Jg. 11 (2021) Nr. 1,

ISSN: 2191-219X

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Guberina, Maja; Darwiche, Kaid; Hautzel, Hubertus; Pöttgen, Christoph; Guberina, Nika; Gauler, Thomas; Ploenes, Till; Umutlu, Lale; Theegarten, Dirk; Aigner, Clemens; Eberhardt, Wilfried; Metzenmacher, Martin; Wiesweg, Marcel; Karpf-Wissel, Rüdiger; Schuler, Martin; Herrmann, Ken; Stuschke, Martin

Patterns of nodal spread in stage III NSCLC : Importance of EBUS-TBNA and ¹⁸F-FDG PET/CT for radiotherapy target volume definition

In: Radiation Oncology Jg. 16 (2021) Nr. 1,

ISSN: 1748-717X

Online Volltext: dx.doi.org/ (Open Access)
Wick, Antje; Bahr, Oliver; Schuler, Martin; Rohrberg, Kristoffer; Chawla, Sant P.; Janku, Filip; Schiff, David; Heinemann, Volker; Narita, Yoshitaka; Lenz, Heinz-Josef; Ikeda, Masafumi; Ando, Yuichi; Wick, Wolfgang; Steinbach, Joachim P.; Burger, Michael C.; Wenger, Katharina; Lassen, Ulrik; Sankhala, Kamalesh K.; Roggia, Cristiana; Genvresse, Isabelle; Munhoz, Catya; Rentzsch, Christine; Reschke, Susanne; Langer, Simon; Wagner, Markus; Kaulfuss, Stefan; Cai, Charles; Lagkadinou, Eleni; Jeffers, Michael; Peña, Carol; Tabatabai, Ghazaleh

Phase I assessment of safety and therapeutic activity of BAY1436032 in patients with IDH1-mutant solid tumors

In: Clinical Cancer Research Jg. 27 (2021) Nr. 10, S. 2723 - 2733

ISSN: 1557-3265; 1078-0432

Online Volltext: dx.doi.org/ (Open Access)
Valdivia, Daniel; Cheufou, Danjouma; Fels, Benjamin; Puhlvers, Stephan; Mardanzai, Khaled; Zaatar, Mohamed; Weinreich, Gerhard; Taube, Christian; Theegarten, Dirk; Stuschke, Martin; Schuler, Martin; Stamatis, Georgios; Hegedus, Balazs; Aigner, Clemens

Potential Prognostic Value of Preoperative Leukocyte Count, Lactate Dehydrogenase and C-Reactive Protein in Thymic Epithelial Tumors

In: Pathology & Oncology Research Jg. 27 (2021) S. 629993

ISSN: 1532-2807; 1219-4956

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Subbiah, Vivek; Hu, Mimi I.; Wirth, Lori J.; Schuler, Martin; Mansfield, Aaron S.; Curigliano, Giuseppe; Brose, Marcia S.; Zhu, Viola W.; Leboulleux, Sophie; Bowles, Daniel W.; Baik, Christina S.; Adkins, Douglas; Keam, Bhumsuk; Matos, Ignacio; Garralda, Elena; Gainor, Justin F.; Lopes, Gilberto; Lin, Chia-Chi; Godbert, Yann; Sarker, Debashis; Miller, Stephen G.; Clifford, Corinne; Zhang, Hui; Turner, Christopher D.; Taylor, Matthew H.

Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW) : a multi-cohort, open-label, registrational, phase 1/2 study

In: The Lancet Diabetes and Endocrinology Jg. 9 (2021) Nr. 8, S. 491 - 501

ISSN: 2213-8595; 2213-8587

Online Volltext: dx.doi.org/
Guberina, Maja; Pöttgen, Christoph; Metzenmacher, Martin; Wiesweg, Marcel; Schuler, Martin; Aigner, Clemens; Ploenes, Till; Umutlu, Lale; Gauler, Thomas; Darwiche, Kaid; Stamatis, Georgios; Theegarten, Dirk; Hautzel, Hubertus; Jentzen, Walter; Guberina, Nika; Herrmann, Ken; Eberhardt, Wilfried E.E.; Stuschke, Martin

Prognostic Value of Postinduction Chemotherapy Volumetric PET/CT Parameters for Stage IIIA or IIIB Non-Small Cell Lung Cancer Patients Receiving Definitive Chemoradiotherapy

In: Journal of Nuclear Medicine (JNM) Jg. 62 (2021) Nr. 12, S. 1684 - 1691

ISSN: 1535-5667; 0161-5505; 2159-662X; 0022-3123; 0097-9058

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Skoulidis, Ferdinandos; Li, Bob T.; Dy, Grace K.; Price, Timothy J.; Falchook, Gerald S.; Wolf, Jürgen; Italiano, Antoine; Schuler, Martin; Borghaei, Hossein; Barlesi, Fabrice; Kato, Terufumi; Curioni-Fontecedro, Alessandra; Sacher, Adrian; Spira, Alexander; Ramalingam, Suresh S.; Takahashi, Toshiaki; Besse, Benjamin; Anderson, Abraham; Ang, Agnes; Tran, Qui; Mather, Omar; Henary, Haby; Ngarmchamnanrith, Gataree; Friberg, Gregory; Velcheti, Vamsidhar; Govindan, Ramaswamy

Sotorasib for Lung Cancers with KRAS p.G12C Mutation

In: The New England Journal of Medicine Jg. 384 (2021) Nr. 25, S. 2371 - 2381

ISSN: 1533-4406; 0028-4793

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Zaun, Gregor; Schuler, Martin

Systemische Tumortherapien des CUP-Syndroms

In: Der Onkologe Jg. 27 (2021) Nr. 7, S. 658 - 662

ISSN: 1433-0415; 0947-8965

Online Volltext: dx.doi.org/
Yang, James Chih-Hsin; Schuler, Martin; Popat, Sanjay; Miura, Satoru; Heeke, Simon; Park, Keunchil; Märten, Angela; Kim, Edward S.

Afatinib for the Treatment of NSCLC Harboring Uncommon EGFR Mutations : A Database of 693 Cases

In: Journal of Thoracic Oncology Jg. 15 (2020) Nr. 5, S. 803 - 815

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Bhat, Hilal; Zaun, Gregor; Hamdan, Thamer A.; Lang, Judith; Adomati, Tom; Schmitz, Rosa; Friedrich, Sarah-Kim; Bergerhausen, Michael; Cham, Lamin B.; Li, Fanghui; Ali, Murtaza; Zhou, Fan; Khairnar, Vishal; Duhan, Vikas; Brandenburg, Tim; Machlah, Yara Maria; Schiller, Maximilian; Berry, Arshia; Xu, Haifeng; Vollmer, Jörg; Häussinger, Dieter; Thier, Beatrice; Pandyra, Aleksandra A.; Schadendorf, Dirk; Paschen, Annette; Schuler, Martin; Lang, Philipp A.; Lang, Karl S.

Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression

In: Frontiers in Immunology Jg. 11 (2020) S. 1849

ISSN: 1664-3224

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Kasper, Stefan; Meiler, Johannes; Knipp, Heike; Höhler, Thomas; Reimer, Peter; Steinmetz, Tilman; Berger, Winfried; Linden, Gabriele; Reis, Henning; Markus, Peter; Paul, Andreas; Dechene, Alexander; Schumacher, Brigitte; Kostbade, Karina; Virchow, Isabel; Ting, Saskia; Worm, Karl; Schmid, Kurt Werner; Herold, Thomas; Wiesweg, Marcel; Schuler, Martin; Trarbach, Tanja

Biweekly Cetuximab Plus FOLFOX6 as First-Line Therapy in Patients With RAS Wild-Type Metastatic Colorectal Cancer : The CEBIFOX Trial

In: Clinical Colorectal Cancer Jg. 19 (2020) Nr. 4, S. 236 - 247.e6

ISSN: 1938-0674; 1533-0028

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Welt, Anja; Wiesweg, Marcel; Theurer, Sarah; Abenhardt, Wolfgang; Groschek, Matthias; Müller, Lothar; Schröder, Jan; Tewes, Mitra; Chiabudini, Marco; Potthoff, Karin; Bankfalvi, Agnes; Marschner, Norbert; Schuler, Martin; Breitenbücher, Frank

Buparlisib in combination with tamoxifen in pretreated patients with hormone receptor-positive, HER2-negative advanced breast cancer molecularly stratified for PIK3CA mutations and loss of PTEN expression

In: Cancer Medicine Jg. 9 (2020) Nr. 13, S. 4527 - 4539

ISSN: 2045-7634

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Wiesweg, Marcel; Herold, Thomas; Metzenmacher, Martin; Eberhardt, Wilfried; Reis, Henning; Darwiche, Kaid; Aigner, Clemens; Stuschke, Martin; Herrmann, Ken; Nensa, Felix; Schildhaus, Hans-Ulrich; Schuler, Martin

Clinical response to crizotinib and emergence of resistance in lung adenocarcinoma harboring a MET c-Cbl binding site mutation

In: Lung Cancer Jg. 139 (2020) S. 165 - 168

ISSN: 1872-8332; 0169-5002

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Bilecz, Agnes; Stockhammer, Paul; Theegarten, Dirk; Kern, Izidor; Jakopovic, Marko; Samarzija, Miroslav; Klikovits, Thomas; Hoda, Mir A.; Döme, Balázs; Oberndorfer, Felicitas; Muellauer, Leonhard; Fillinger, János; Kovács, Ildikó; Pirker, Christine; Schuler, Martin; Plönes, Till; Aigner, Clemens; Klepetko, Walter; Berger, Walter; Brcic, Luka; Laszlo, Viktória; Hegedus, Balazs

Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma

In: Histopathology Jg. 77 (2020) Nr. 1, S. 55 - 66

ISSN: 1365-2559; 0309-0167

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Guberina, Nika; Pöttgen, Christoph; Schuler, Martin; Guberina, Maja; Stamatis, Georgios; Plönes, Till; Krebs, Bettina; Metzenmacher, Martin; Theegarten, Dirk; Gauler, Thomas; Jöckel, Karl-Heinz; Darwiche, Kaid; Aigner, Clemens; Stuschke, Martin; Eberhardt, Wilfried

Comparison of early tumour-associated versus late deaths in patients with central or >7 cm T4 N0/1 M0 non-small-cell lung-cancer undergoing trimodal treatment : Only few risks left to improve

In: European Journal of Cancer (EJC) Jg. 138 (2020) S. 156 - 168

ISSN: 1879-0852; 0959-8049; 1879-2995

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Wiesweg, Marcel; Schuler, Martin; Schildhaus, Hans-Ulrich

Crizotinib in ROS1 and MET deregulated NSCLC-letter

In: Clinical Cancer Research Jg. 26 (2020) Nr. 7, S. 1774

ISSN: 1557-3265; 1078-0432

Online Volltext: dx.doi.org/ (Open Access)
Stockhammer, Paul; Ploenes, Till; Theegarten, Dirk; Schuler, Martin; Maier, Sandra; Aigner, Clemens; Hegedus, Balazs

Detection of TGF-β in pleural effusions for diagnosis and prognostic stratification of malignant pleural mesothelioma

In: Lung Cancer Jg. 139 (2020) S. 124 - 132

ISSN: 1872-8332; 0169-5002

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Reissig, Timm M.; Sara, Linda; Ting, Saskia; Reis, Henning; Metzenmacher, Martin; Eberhardt, Wilfried; Zaun, Gregor; Herold, Thomas; Aigner, Clemens; Darwiche, Kaid; Stuschke, Martin; Schildhaus, Hans-Ulrich; Schuler, Martin; Wiesweg, Marcel

ERK phosphorylation as a marker of RAS activity and its prognostic value in non-small cell lung cancer

In: Lung Cancer Jg. 149 (2020) S. 10 - 16

ISSN: 1872-8332; 0169-5002

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Peuker, CA; Yaghobramzi, S; Lüftner, D.; Brucker, S; Decker, T; Fasching, P; Fehm, T; Janni, W; Kümmel, Sherko; Schneeweiss, A; Schuler, Martin; Busse, A

Einfluss des CDK4/6-Inhibitors Ribociclib auf die periphere Immunantwort beim Hormonrezeptor-positiven Mammakarzinom

In: Geburtshilfe und Frauenheilkunde Jg. 80 (2020) Nr. 6, S. e53

ISSN: 1438-8804; 0016-5751

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Frikkel, Johanna; Götte, Miriam; Beckmann, Mingo B.; Kasper, Stefan; Hense, Jörg; Teufel, Martin; Schuler, Martin; Tewes, Mitra

Fatigue, barriers to physical activity and predictors for motivation to exercise in advanced Cancer patients

In: BMC Palliative Care Jg. 19 (2020) Nr. 1, S. 43

ISSN: 1472-684X

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Nothdurft, Silke; Thumser-Henner, Clotilde; Breitenbücher, Frank; Okimoto, Ross A.; Dorsch, Madeleine; Opitz, Christiane A.; Sadik, Ahmed; Esser, Charlotte; Hölzel, Michael; Asthana, Saurabh; Forster, Jan; Beisser, Daniela; Kalmbach, Sophie; Grüner, Barbara M.; Bivona, Trever G.; Schramm, Alexander; Schuler, Martin

Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis

In: Oncogenesis Jg. 9 (2020) Nr. 11, S. 102

ISSN: 2157-9024

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Stockhammer, Paul; Ho, Cassandra Su Lyn; Hegedus, Luca; Lotz, Gabor; Molnár, Eszter; Bankfalvi, Agnes; Herold, Thomas; Kalbourtzis, Stavros; Ploenes, Till; Eberhardt, Wilfried; Schuler, Martin; Aigner, Clemens; Schramm, Alexander; Hegedus, Balazs

HDAC inhibition synergizes with ALK inhibitors to overcome resistance in a novel ALK mutated lung adenocarcinoma model

In: Lung Cancer Jg. 144 (2020) S. 20 - 29

ISSN: 1872-8332; 0169-5002

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Welt, Anja; Bogner, Simon; Arendt, Marina; Kossow, Josef; Huffziger, Antonia; Pohlkamp, Christian; Steiniger, Heike; Becker, Ute; Alashkar, Ferras; Kohl, Marzena; Wiesweg, Marcel; Richly, Heike; Hense, Jörg; Scheulen, Max Ernst; Schuler, Martin; Seeber, Siegfried; Tewes, Mitra

Improved survival in metastatic breast cancer : results from a 20-year study involving 1033 women treated at a single comprehensive cancer center

In: Journal of Cancer Research and Clinical Oncology (2020)

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

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Wiesweg, Marcel; Mairinger, Fabian; Reis, Henning; Goetz, Moritz; Kollmeier, Jens; Misch, Daniel; Stephan-Falkenau, Susann; Mairinger, Thomas; Walter, Robert F.H.; Hager, Thomas; Metzenmacher, Martin; Eberhardt, Wilfried; Zaun, Gregor; Köster, Johannes; Stuschke, Martin; Aigner, Clemens; Darwiche, Kaid; Schmid, Kurt Werner; Rahmann, Sven; Schuler, Martin

Machine learning reveals a PD-L1–independent prediction of response to immunotherapy of non-small cell lung cancer by gene expression context

In: European Journal of Cancer (EJC) Jg. 140 (2020) S. 76 - 85

ISSN: 1879-0852; 0959-8049; 1879-2995

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Schuler, Martin; Berardi, Rossana; Lim, Darren Wan Teck; de Jonge, Maja J. A.; Bauer, Todd M.; Azaro, Analía; Gottfried, Maya; Han, Jiyoun; Lee, Dae-hee; Wollner, M.; Hong, David S.; Vogel, Arndt; Delmonte, Angelo; Akimov, Mikhail; Ghebremariam, Samson; Cui, X.; Nwana, N.; Giovannini, Monica; Kim, Tae-min

Molecular correlates of response to capmatinib in advanced non-small-cell lung cancer : Clinical and biomarker results from a phase I trial

In: Annals of Oncology Jg. 31 (2020) Nr. 6, S. 789 - 797

ISSN: 1569-8041; 0923-7534

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Bang, Yung-Jue; Su, Wu-Chou; Schuler, Martin; Nam, Do-Hyun; Lim, Wan Teck; Bauer, Todd M.; Azaro, Analia; Poon, Ronnie Tung Ping; Hong, David; Lin, Chia-Chi; Akimov, Mikhail; Ghebremariam, Samson; Zhao, Sylvia; Giovannini, Monica; Ma, Brigette

Phase 1 study of capmatinib in MET-positive solid tumor patients : Dose escalation and expansion of selected cohorts

In: Cancer Science Jg. 111 (2020) Nr. 2, S. 536 - 547

ISSN: 1349-7006; 1347-9032

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Bardia, Aditya; Gounder, Mrinal; Rodon, Jordi; Janku, Filip; Lolkema, Martijn P.; Stephenson, Joe J.; Bedard, Philippe L.; Schuler, Martin; Sessa, Cristiana; LoRusso, Patricia; Thomas, Michael; Maacke, Heiko; Evans, Helen; Sun, Yongjian; Tan, Daniel S.W.

Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3-Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations

In: The Oncologist Jg. 24 (2020) Nr. 1, S. e160 - e169

ISSN: 1083-7159; 2159-8401; 1549-490X

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Metzenmacher, Martin; Váraljai, Renáta; Hegedüs, Balazs; Cima, Igor; Forster, Jan; Schramm, Alexander; Scheffler, Björn; Horn, Peter; Klein, Christoph A.; Szarvas, Tibor; Reis, Henning; Bielefeld, Nicola; Rösch, Alexander; Aigner, Clemens; Kunzmann, Volker; Wiesweg, Marcel; Siveke, Jens; Schuler, Martin; Lueong, Smiths S.

Plasma next generation sequencing and droplet digital-qpcr-based quantification of circulating cell-free rna for noninvasive early detection of cancer

In: Cancers Jg. 12 (2020) Nr. 2, S. 353

ISSN: 2072-6694

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Such, Lina; Zhao, Fang; Liu, Derek; Thier, Beatrice; Le-Trilling, Vu Thuy Khanh; Sucker, Antje; Coch, Christoph; Pieper, Natalia; Howe, Sebastian; Bhat, Hilal; Kalkavan, Halime; Ritter, Cathrin; Brinkhaus, Robin; Ugurel, Selma; Köster, Johannes; Seifert, Ulrike; Dittmer, Ulf; Schuler, Martin; Lang, Karl S.; Kufer, Thomas A.; Hartmann, Gunther; Becker, Jürgen; Horn, Susanne; Ferrone, Soldano; Liu, David; Van Allen, Eliezer M.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Paschen, Annette

Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy

In: The Journal of Clinical Investigation (JCI) Jg. 130 (2020) Nr. 8, S. 4266 - 4281

ISSN: 1558-8238; 0021-9738

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Schuler, Martin

The quest for efficient trial designs in precision oncology

In: The Lancet Oncology Jg. 21 (2020) Nr. 12, S. 1539 - 1541

ISSN: 1474-5488; 1470-2045

Online Volltext: dx.doi.org/
Ghanim, Bahil; Rosenmayr, Anna; Stockhammer, Paul; Vogl, Melanie; Celik, Ali; Bas, Aynur; Kurul, Ismail Cuneyt; Akyurek, Nalan; Varga, Alexander; Plönes, Till; Bankfalvi, Agnes; Hager, Thomas; Schuler, Martin; Hackner, Klaus; Errhalt, Peter; Scheed, Axel; Seebacher, Gernot; Hegedus, Balazs; Stubenberger, Elisabeth; Aigner, Clemens

Tumour cell PD-L1 expression is prognostic in patients with malignant pleural effusion : the impact of C-reactive protein and immune-checkpoint inhibition

In: Scientific Reports Jg. 10 (2020) Nr. 1, S. 5784

ISSN: 2045-2322

Online Volltext: dx.doi.org/ (Open Access)
Türeci, Özlem; Sahin, Ugur; Schulze-Bergkamen, Henning; Zvirbule, Zanete; Lordick, Florian; Koeberle, Dieter; Thuss-Patience, Peter C.; Ettrich, Thomas J.; Arnold, Dirk; Bassermann, Florian; Al-Batran, Salah Eddin; Wiechen, K.; Dhaene, Karl F. L.; Maurus, D.; Gold, M.; Huber, Christopher H.; Krivoshik, Andrew P.; Arozullah, A.; Park, J. W.; Schuler, Martin

A multicentre, phase IIa study of zolbetuximab as a single agent in patients with recurrent or refractory advanced adenocarcinoma of the stomach or lower oesophagus : the MONO study

In: Annals of Oncology Jg. 30 (2019) Nr. 9, S. 1487 - 1495

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Taylor, Matthew H.; Gainor, Justin F.; Hu, Mimi I-Nan; Zhu, Viola Weijia; Lopes, Gilberto; Leboulleux, Sophie; Brose, Marcia S.; Schuler, Martin; Bowles, Daniel W.; Kim, Dong-Wan; Baik, Christina S; Garralda, Elena; Lin, Chia-Chi; Adkins, Douglas; Sarker, Debashis; Curigliano, Giuseppe; Zhang, Hui; Clifford, Corinne; Turner, Christopher D.; Subbiah, Vivek

Activity and tolerability of BLU-667, a highly potent and selective RET inhibitor, in patients with advanced RET-altered thyroid cancers

In: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 15_Suppl, S. 6018

ISSN: 0732-183X; 1527-7755

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Juric, Dejan; Janku, Filip; Rodón, Jordi; Burris, Howard A.; Mayer, Ingrid A.; Schuler, Martin; Seggewiss-Bernhardt, Ruth; Gil-Martin, Marta; Middleton, Mark R.; Baselga, José; Bootle, Douglas; Demanse, David; Blumenstein, Lars; Schumacher, Karl; Huang, Alan; Quadt, Cornelia; Rugo, Hope S.

Alpelisib Plus Fulvestrant in PIK3CA -Altered and PIK3CA -Wild-Type Estrogen Receptor-Positive Advanced Breast Cancer : A Phase 1b Clinical Trial

In: JAMA Oncology Jg. 5 (2019) Nr. 2, S. e184475

ISSN: 2374-2445; 2374-2437

Online Volltext: dx.doi.org/ (Open Access)
Totzeck, Matthias; Schuler, Martin; Stuschke, Martin; Heusch, Gerd; Rassaf, Tienush

Cardio-oncology - strategies for management of cancer-therapy related cardiovascular disease

In: International Journal of Cardiology Jg. 280 (2019) S. 163 - 175

ISSN: 0167-5273; 1874-1754

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Kleinhans, J.; Gauler, Thomas; Wrede, Karsten; Schuler, Martin; Aigner, Clemens; Stamatis, Georgios; Eberhardt, Wilfried; Stuschke, Martin

Cerebral Recurrence after trimodal Therapy of Patients with locally advanced NSCLC - Prognostic Factors and prognostic Importance

In: Strahlentherapie und Onkologie Jg. 195 (2019) Nr. Suppl. 1, S. S66 - S67

ISSN: 0179-7158; 1439-099X
Subbiah, Vivek; Gervais, Radj; Riely, Gregory; Hollebecque, Antoine; Blay, Jean-Yves; Felip, Enriqueta; Schuler, Martin; Gonçalves, Anthony; Italiano, Antonio; Keedy, Vicki; Chau, Ian; Puzanov, Igor; Raje, Noopur S.; Meric-Bernstam, Funda; Makrutzki, Martina; Riehl, Todd; Pitcher, Bethany; Baselga, Jose; Hyman, David M.

Efficacy of vemurafenib in patients with non–small-cell lung cancer with BRAF V600 mutation : An open-label, single-arm cohort of the histology-independent VE-Basket study

In: JCO Precision Oncology Jg. 3 (2019) S. 1 - 9

ISSN: 2473-4284

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Paz-Ares, Luis; Sequist, Lecia V.; Hirsh, Vera; Lee, Ki Hyeong; Wu, Yi-Long; Lu, Shun; Zhou, Caicun; Feng, Jifeng; Ellis, Stuart H.; Samuelsen, Carl H.; Tang, Wenbo; Märten, Angela; Ehrnrooth, Eva; Park, Keunchil; Yang, James Chih-Hsin

First-line afatinib for advanced EGFRm+ NSCLC : Analysis of long-term responders in the LUX-Lung 3, 6, and 7 trials

In: Lung Cancer Jg. 133 (2019) S. 10 - 19

ISSN: 1872-8332; 0169-5002

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Tan, Eng-Huat; O’Byrne, Kenneth; Zhang, Li; Boyer, Michael; Mok, Tony; Hirsh, Vera; Yang, James Chih-Hsin; Lee, Ki Hyeong; Lu, Shun; Shi, Yuankai; Kim, Sang-We; Laskin, Janessa; Kim, Dong-Wan; Arvis, Catherine Dubos; Kölbeck, Karl; Massey, Dan; Märten, Angela; Paz-Ares, Luis; Park, Keunchil

First-line afatinib vs gefitinib for patients with EGFR mutation-positive NSCLC (LUX-Lung 7) : impact of afatinib dose adjustment and analysis of mode of initial progression for patients who continued treatment beyond progression

In: Journal of Cancer Research and Clinical Oncology Jg. 145 (2019) Nr. 6, S. 1569 - 1579

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

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Joos, Stefan; Nettelbeck, Dirk M.; Reil-Held, Anette; Engelmann, Katja; Moosmann, Alexandra; Eggert, Angelika; Hiddemann, Wolfgang; Krause, Mechthild; Peters, Christoph; Schuler, Martin; Schulze-Osthoff, Klaus; Serve, Hubert; Wick, Wolfgang; Puchta, Josef; Baumann, Michael

German Cancer Consortium (DKTK) : A national consortium for translational cancer research

In: Molecular Oncology Jg. 13 (2019) Nr. 3, S. 535 - 542

ISSN: 1878-0261; 1574-7891

Online Volltext: dx.doi.org/ (Open Access)
Wiesweg, Marcel; Kasper, Stefan; Worm, Karl; Herold, Thomas; Reis, Henning; Sara, Linda; Metzenmacher, Martin; Abendroth, Annalena; Darwiche, Kaid; Aigner, Clemens; Wedemeyer, Heiner; Helfritz, Fabian A.; Stuschke, Martin; Schumacher, Brigitte; Markus, Peter; Paul, Andreas; Rahmann, Sven; Schmid, Kurt Werner; Schuler, Martin

Impact of RAS mutation subtype on clinical outcome : a cross-entity comparison of patients with advanced non-small cell lung cancer and colorectal cancer

In: Oncogene Jg. 38 (2019) Nr. 16, S. 2953 - 2966

ISSN: 0950-9232; 1476-5594

Online Volltext: dx.doi.org/
Abendroth, A.; Noureddine, R.; Abramczyk, M.; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Markus, P.; Schumacher, B.; Wiesweg, Marcel; Köhler, Johannes; Markus, M.; Mende, B.; Dechene, Alexander; Schuler, Martin; Kasper, Stefan

Long-term outcome of patients with advanced pancreatic cancer treated with sequential chemotherapies before the era of modern combination therapy protocols

In: Journal of Cancer Research and Clinical Oncology Jg. 145 (2019) Nr. 2, S. 445 - 455

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

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Cheufou, Danjouma Housmanou; Valdivia, Daniel; Puhlvers, Stephan; Fels, Benjamin; Weinreich, Gerhard; Taube, Christian; Theegarten, Dirk; Stuschke, Martin; Schuler, Martin; Hegedus, Balazs; Stamatis, Georgios; Aigner, Clemens

Lymph Node Involvement and the Surgical Treatment of Thymic Epithelial and Neuroendocrine Carcinoma

In: The Annals of Thoracic Surgery Jg. 107 (2019) Nr. 6, S. 1632 - 1638

ISSN: 0003-4975; 1552-6259

Online Volltext: dx.doi.org/ (Open Access)
Wiesweg, Marcel; Mairinger, Fabian; Reis, Henning; Goetz, Moritz; Walter, Robert; Hager, Thomas; Metzenmacher, Martin; Eberhardt, Wilfried; McCutcheon, A.; Köster, J.; Stuschke, Martin; Aigner, Clemens; Darwiche, Kaid; Schmid, Kurt Werner; Rahmann, Sven; Schuler, Martin

Machine learning-based predictors for immune checkpoint inhibitor therapy of non-small-cell lung cancer

In: Annals of Oncology Jg. 30 (2019) Nr. 4, S. 655 - 657

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Al-Batran, Salah-Eddin; Homann, Nils; Pauligk, Claudia; Goetze, Thorsten O.; Meiler, Johannes; Kasper, Stefan; Kopp, Hans-Georg; Mayer, Frank; Haag, Georg Martin; Luley, Kim; Lindig, Udo; Schmiegel, Wolff; Pohl, Michael; Stoehlmacher, Jan; Folprecht, Gunnar; Probst, Stephan; Prasnikar, Nicole; Fischbach, Wolfgang; Mahlberg, Rolf; Trojan, Jörg; Koenigsmann, Michael; Martens, Uwe M.; Thuss-Patience, Peter; Egger, Matthias; Block, Andreas; Heinemann, Volker; Illerhaus, Gerald; Moehler, Markus; Schenk, Michael; Kullmann, Frank; Behringer, Dirk M.; Heike, Michael; Pink, Daniel; Teschendorf, Christian; Löhr, Carmen; Bernhard, Helga; Schuch, Gunter; Rethwisch, Volker; Weikersthal, Ludwig Fischer von; Hartmann, Jörg T.; Kneba, Michael; Daum, Severin; Schulmann, Karsten; Weniger, Jörg; Belle, Sebastian; Gaiser, Timo; Oduncu, Fuat S.; Güntner, Martina; Hozaeel, Wael; Reichart, Alexander; Jäger, Elke; Kraus, Thomas; Mönig, Stefan; Bechstein, Wolf O.; Schuler, Martin; Schmalenberg, Harald; Hofheinz, Ralf D.

Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4) : a randomised, phase 2/3 trial

In: Lancet Jg. 393 (2019) Nr. 10184, S. 1948 - 1957

ISSN: 1474-547X; 0140-6736; 0023-7507

Online Volltext: dx.doi.org/
Guberina, Maja; Eberhardt, Wilfried; Stuschke, Martin; Gauler, Thomas; Aigner, Clemens; Schuler, Martin; Stamatis, Georgios; Theegarten, Dirk; Jentzen, Walter; Herrmann, Ken; Pöttgen, Christoph

Pretreatment metabolic tumour volume in stage IIIA/B non-small-cell lung cancer uncovers differences in effectiveness of definitive radiochemotherapy schedules : analysis of the ESPATUE randomized phase 3 trial

In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 46 (2019) Nr. 7, S. 1439 - 1447

ISSN: 1619-7089; 1619-7070; 0340-6997

Online Volltext: dx.doi.org/
Schuler, Martin; Cho, Byoung Chul; Sayehli, Cyrus Michael; Navarro, Alejandro; Soo, Ross A.; Richly, Heike; Cassier, Philippe Alexandre; Tai, David; Penel, Nicolas; Nogova, Lucia; Park, Se Hoon; Schostak, Martin; Gajate, Pablo; Cathomas, Richard; Rajagopalan, Prabhu; Grevel, Joachim; Bender, Sebastian; Boix, Oliver; Nogai, Hendrik; Ocker, Matthias; Ellinghaus, Peter; Joerger, Markus

Rogaratinib in patients with advanced cancers selected by FGFR mRNA expression : a phase 1 dose-escalation and dose-expansion study

In: The Lancet Oncology Jg. 20 (2019) Nr. 10, S. 1454 - 1466

ISSN: 1474-5488; 1470-2045

Online Volltext: dx.doi.org/
Park, Keunchil; Bennouna, Jaafar; Boyer, Michael; Hida, Toyoaki; Hirsh, Vera; Kato, Terufumi; Lu, Shun; Mok, Tony; Nakagawa, Kazuhiko; O'Byrne, Kenneth; Paz-Ares, Luis; Schuler, Martin; Sibilot, Denis Moro; Tan, Eng-Huat; Tanaka, Hiroshi; Wu, Yi-Long; Yang, James C.-H.; Zhang, Li; Zhou, Caicun; Märten, Angela; Tang, Wenbo; Yamamoto, Nobuyuki

Sequencing of therapy following first-line afatinib in patients with EGFR mutation-positive non-small cell lung cancer

In: Lung Cancer Jg. 132 (2019) S. 126 - 131

ISSN: 1872-8332; 0169-5002

Online Volltext: dx.doi.org/ (Open Access)
Pastille, Eva; Wasmer, Marie-Hélène; Adamczyk, Alexandra; Vu, Vivian P.; Mager, Lukas F.; Phuong, Nhi Ngo Thi; Palmieri, Vittoria; Simillion, Cedric; Hansen, Wiebke; Kasper, Stefan; Schuler, Martin; Muggli, Beat; McCoy, Kathy D.; Buer, Jan; Zlobec, Inti; Westendorf, Astrid; Krebs, Philippe

The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer

In: Mucosal Immunology Jg. 12 (2019) Nr. 4, S. 990 - 1003

ISSN: 1933-0219; 1935-3456

Online Volltext: dx.doi.org/ (Open Access)
Sahin, Ugur; Tureci, Özlem; Manikhas, Georgy M.; Lordick, Florian; Rusyn, Andriy; Vynnychenko, Ihor; Dudov, Assen; Bazin, Igor; Bondarenko, Igor; Melichar, Bohuslav; Dhaene, Karl; Wiechen, Kai; Maurus, Daniel; Schuler, Martin; Al-Batran, Salah-Eddin

Zolbetuximab combined with EOX as first-line therapy in advanced CLDN18.2+ gastric (G) and gastroesophageal junction (GEJ) adenocarcinoma : Updated results from the FAST trial.

In: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 4_Suppl, S. 16

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Tamiya, A.; Märten, A.; Popat, S.; Yamamoto, N.; Yang, J.C-H.; Hirsh, V.; Wu, Y-L.; Schuler, Martin; O'Byrne, K.

143PD Competing central nervous system or systemic progression analysis for patients with EGFR mutation-positive NSCLC receiving afatinib in LUX-Lung 3, 6, and 7

In: Journal of Thoracic Oncology Jg. 13 (2018) Nr. 4, S. S84 - S85

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Sahin, Ugur; Schuler, Martin; Richly, Heike; Bauer, Stefan; Krilova, Anna; Dechow, Tobias; Jerling, Markus; Utsch, Magdalena; Rohde, Christoph; Dhaene, Karl; Huber, Christoph; Türeci, Özlem

A phase I dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer

In: European Journal of Cancer Jg. 100 (2018) S. 17 - 26

ISSN: 0964-1947; 0959-8049

Online Volltext: dx.doi.org/ (Open Access)
Wu, Yi-Long; Sequist, Lecia V.; Tan, Eng-Huat; Geater, Sarayut L.; Orlov, Sergey; Zhang, Li; Lee, Ki Hyeong; Tsai, Chun-Ming; Kato, Terufumi; Barrios, Carlos H.; Schuler, Martin; Hirsh, Vera; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Boyer, Michael; Mok, Tony; Peil, Barbara; Märten, Angela; Chih-Hsin Yang, James; Paz-Ares, Luis; Park, Keunchil

Afatinib as First-line Treatment of Older Patients With EGFR Mutation-Positive Non–Small-Cell Lung Cancer : Subgroup Analyses of the LUX-Lung 3, LUX-Lung 6, and LUX-Lung 7 Trials

In: Clinical Lung Cancer Jg. 19 (2018) Nr. 4, S. e465 - e479

ISSN: 1938-0690; 1525-7304

Online Volltext: dx.doi.org/ (Open Access)
Zaun, Gregor; Schuler, Martin; Herrmann, Ken; Tannapfel, Andrea

CUP syndrome : Metastatic malignancy with unknown primary tumor

In: Deutsches Ärzteblatt international Jg. 115 (2018) Nr. 10, S. 157 - 162

ISSN: 1866-0452

Online Volltext: dx.doi.org/ (Open Access)
Yang, J. C.; Wu, Y.; Hirsh, V.; O'Byrne, K.; Yamamoto, N.; Popat, S.; Tamiya, A.; Kaen, D.; Marten, A.; Schuler, Martin

Competing CNS or Systemic Progression Analysis for EGFR Mutation-Positive NSCLC Patients on Afatinib in LUX-Lung 3, 6, and 7

In: Journal of Thoracic Surgery Jg. 13 (2018) Nr. Suppl. 9, S. 163

ISSN: 1556-0864; 1556-1380
Yang, J.C.-.; Wu, Y.; Hirsh, V.; O’Byrne, K.; Yamamoto, N.; Popat, S.; Tamiya, A.; Kaen, D.; Märten, A.; Schuler, Martin

Competing CNS or Systemic Progression Analysis for EGFR Mutation-Positive NSCLC Patients on Afatinib in LUX-Lung 3, 6, and 7

In: Journal of Thoracic Oncology Jg. 13 (2018) Nr. 9, Suppl., S. 163

ISSN: 1556-1380

Online Volltext: dx.doi.org/ (Open Access)
Wu, Yi-Long; Hirsh, Vera; Sequist, Lecia V.; Hu, Cheng-Ping; Feng, Jifeng; Lu, Shun; Huang, Yunchao; Schuler, Martin; Mok, Tony; Yamamoto, Nobuyuki; O’Byrne, Kenneth; Geater, Sarayut L.; Zhou, Caicun; Massey, Dan; Märten, Angela; Lungershausen, Juliane; Yang, James Chih-Hsin

Does EGFR Mutation Type Influence Patient-Reported Outcomes in Patients with Advanced EGFR Mutation-Positive Non-Small-Cell Lung Cancer? Analysis of Two Large, Phase III Studies Comparing Afatinib with Chemotherapy (LUX-Lung 3 and LUX-Lung 6)

In: The Patient Jg. 11 (2018) Nr. 1, S. 131 - 141

ISSN: 1178-1653; 1178-1661

Online Volltext: dx.doi.org/ (Open Access)
Hamacher, Rainer; Kämpfe, Dietrich; Reuter-Jessen, Kirsten; Pöttgen, Christoph; Podleska, Lars; Farzaliyev, Farhad; Steinau, Hans-Ulrich; Schuler, Martin; Schildhaus, Hans-Ulrich; Bauer, Sebastian

Dramatic response of a PD-L1- positive advanced angiosarcoma of the scalp to pembrolizumab

In: JCO Precision Oncology Jg. 2 (2018)

ISSN: 2473-4284

Online Volltext: dx.doi.org/
Cappuzzo, Federico; Soo, Ross; Hochmair, Maximilian; Schuler, Martin; Lam, Kwok Chi; Stehle, Gerd; Cseh, Agnieszka; Lorence, Robert M; Linden, Stephan; Forman, Nicole D; Hilbe, Wolfgang; Jazieh, Abdul Rahman; Tsai, Chun-Ming

Global named patient use program of afatinib in advanced non-small-cell lung carcinoma patients who progressed following prior therapies

In: Future Oncology Jg. 14 (2018) Nr. 15, S. 1477 - 1486

ISSN: 1744-8301; 1479-6694

Online Volltext: dx.doi.org/ (Open Access)
Grünwald, Viktor; Schuler, Martin H.; Schöffski, Patrick; Kopp, Hans-Georg; Bauer, Sebastian; Kasper, Bernd; Lindner, Lars H.; Chemnitz, Jens M.; Crysandt, Martina; Stein, Alexander; Steffen, B.; Richter, Stephan; Kneba, Michael; Egerer, Gerlinde; Zimmermann, S.; Karch, Annika; Kunitz, Annegret

Health-related quality of life (HR-QoL) in elderly soft tissue sarcoma (STS) patients from the randomized phase II EPAZ study comparing pazopanib (PAZ) and doxorubicin (DOX) in first line

In: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 8, S. viii577

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/ (Open Access)
Gautschi, O.; Drilon, A.; Milia, J.; Lusque, A.; Mhanna, L.; Li, B.; Sabari, J.; Cortot, A.; Besse, B.; Mezquita, L.; Solomon, B.; Thai, A.; Couraud, S.; Veilion, R.; Mascaux, C.; Barlesi, F.; Van den Heuvel, M.; Schouten, R.; Wakelee, H.; Mah, A.; Camidge, D. R.; Ng, T.; Peled, N.; Lilach, Y.; Popat, S.; Ou, S.; Zhu, V.; Velcheti, V.; Fontecedro, A. C.; Akhoundova, D.; Fruh, M.; Zalcman, G.; Gounant, V.; Novello, S.; Bironzo, P.; Felip, E.; Martinez-Marti, A.; Moro-Sibilot, D.; Rosell, R.; Karachaliou, N.; Schuler, Martin; Wiesweg, Marcel; Diebold, J.; Mazieres, J.

Immunotherapy for Non-Small Cell Lung Cancers (NSCLC) with Oncogenic Driver Mutations : New Results from the Global IMMUNOTARGET Registry

In: Journal of Thoracic Oncology Jg. 13 (2018) Nr. Suppl. 10, S. 367

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Nadjm, S.; Pöttgen, Christoph; Gauler, Thomas; Exner, J. P.; Krebs, B.; Cheufou, D.; Umutlu, Lale; Deuschl, C.; Darwiche, Kaid; Schuler, Martin; Eberhardt, Wilfried; Stuschke, Martin

Investigations of Long-term Survivors with locally advanced NSCLC on Morbidity of curative Therapy - Analysis of neurocognitive Effects

In: Strahlentherapie und Onkologie Jg. 194 (2018) Nr. Suppl. 1, S. 110

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/ (Open Access)
Reis, Henning; Metzenmacher, Martin; Goetz, Moritz; Savvidou, Nikoleta; Darwiche, Kaid; Aigner, Clemens; Herold, Thomas; Eberhardt, Wilfried; Skiba, Charlotte; Hense, Jörg; Virchow, Isabel; Westerwick, Daniela; Bogner, Simon; Ting, Saskia; Kasper, Stefan; Stuschke, Martin; Nensa, Felix; Herrmann, Ken; Hager, Thomas; Schmid, Kurt Werner; Schuler, Martin; Wiesweg, Marcel

MET Expression in Advanced Non–Small-Cell Lung Cancer : Effect on Clinical Outcomes of Chemotherapy, Targeted Therapy, and Immunotherapy

In: Clinical Lung Cancer Jg. 19 (2018) Nr. 4, S. e441 - e463

ISSN: 1938-0690; 1525-7304

Online Volltext: dx.doi.org/
Reis, Henning; van der Vos, Kristan E.; Niedworok, Christian; Herold, Thomas; Módos, Orsolya; Szendroi, Attila; Hager, Thomas; Ingenwerth, Marc; Vis, Daniël J.; Behrendt, Mark A.; de Jong, Jeroen; van der Heijden, Michiel S.; Peyronnet, Benoit; Mathieu, Romain; Wiesweg, Marcel; Ablat, Jason; Okon, Krzysztof; Tolkach, Yuri; Keresztes, David; Nagy, Nikolett; Bremmer, Felix; Gaisa, Nadine T.; Chlosta, Piotr; Kriegsmann, Joerg; Kovalszky, Ilona; Timar, József; Kristiansen, Glen; Radzun, Heinz-Joachim; Knüchel, Ruth; Schuler, Martin; Black, Peter C.; Rübben, Herbert; Hadaschik, Boris; Schmid, Kurt Werner; van Rhijn, Bas W.G.; Nyirády, Péter; Szarvas, Tibor

Pathogenic and targetable genetic alterations in 70 urachal adenocarcinomas

In: International Journal of Cancer Jg. 143 (2018) Nr. 7, S. 1764 - 1773

ISSN: 0020-7136; 1097-0215

Online Volltext: dx.doi.org/ (Open Access)
Tewes, Mitra; Rettler, Teresa Maria; Beckmann, Mingo; Scheer, Karin; Ritterbusch, Ulrike; Schuler, Martin; Hense, Jörg

Patient-Reported-Outcome-Messung (PROM) psychosozialer Belastung und Symptome für ambulante Patienten unter kurativer oder palliativer Tumortherapie : eine retrospektive Analyse eines Comprehensive Cancer Center

In: Der Onkologe Jg. 24 (2018) Nr. 1, S. 69 - 75

ISSN: 1433-0415; 0947-8965

Online Volltext: dx.doi.org/
Rodon, Jordi; Pérez-Fidalgo, Alejandro; Krop, Ian E.; Burris, Howard; Guerrero-Zotano, Angel; Britten, Carolyn D.; Becerra, Carlos; Schellens, Jan; Richards, Donald A.; Schuler, Martin; Abu-Khalaf, Maysa; Johnson, Faye M.; Ranson, Malcolm; Edenfield, Jeff; Silva, Antonio P.; Hackl, Wolfgang; Quadt, Cornelia; Demanse, David; Duval, Vincent; Baselga, Jose

Phase 1/1b dose escalation and expansion study of BEZ235, a dual PI3K/mTOR inhibitor, in patients with advanced solid tumors including patients with advanced breast cancer

In: Cancer Chemotherapy and Pharmacology Jg. 82 (2018) Nr. 2, S. 285 - 298

ISSN: 0344-5704; 1432-0843

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Juric, Dejan; Rodon, Jordi; Tabernero, Josep; Janku, Filip; Burris, Howard A.; Schellens, Jan H.M.; Middleton, Mark R.; Berlin, Jordan; Schuler, Martin; Marta, Gil-Martin; Rugo, Hope S.; Ruth, Seggewiss-Bernhardt; Huang, Alan; Bootle, Douglas; Demanse, David; Blumenstein, Lars; Coughlin, Christina; Quadt, Cornelia; Baselga, José

Phosphatidylinositol 3-kinase a–selective inhibition with alpelisib (BYL719) in PIK3CA-altered solid tumors : Results from the first-in-human study

In: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. 13, S. 1291 - 1299

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Wiesweg, Marcel; Reis, Henning; Köster, Tobias; Goetz, Moritz; Worm, Karl; Herold, Thomas; Paul, Andreas; Dechene, Alexander; Schumacher, Brigitte; Markus, Peter; Virchow, Isabel; Kostbade, Karina; Wolf, Nathalie; Zaun, Gregor; Metzenmacher, Martin; Schmid, Kurt Werner; Schuler, Martin; Kasper, Stefan

Phosphorylation of p70 Ribosomal Protein S6 Kinase β-1 is an Independent Prognostic Parameter in Metastatic Colorectal Cancer

In: Clinical Colorectal Cancer Jg. 17 (2018) Nr. 2, S. e331 - e352

ISSN: 1938-0674; 1533-0028

Online Volltext: dx.doi.org/
Guberina, M.; Eberhardt, Wilfried; Stuschke, Martin; Gauler, Thomas; Aigner, Clemens; Schuler, Martin; Stamatis, Georgios; Pöttgen, Christoph

Pre-therapeutic metabolic Tumor Volume (MTV) in (18) F-FDG-PET/CT as a prognostic Factor in Patients with Stage IIIA-IIIB NSCLC before Trimodal Therapy or definitive Chemoradiotherapy - Results of Phase 3 Study

In: Strahlentherapie und Onkologie Jg. 194 (2018) Nr. Suppl.1, S. S41 - S42

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/ (Open Access)
Tewes, Mitra; Rettler, Teresa; Wolf, Nathalie; Hense, Jörg; Schuler, Martin; Teufel, Martin; Beckmann, Mingo

Predictors of outpatients’ request for palliative care service at a medical oncology clinic of a German comprehensive cancer center

In: Supportive Care in Cancer Jg. 26 (2018) Nr. 10, S. 3641 - 3647

ISSN: 1433-7339; 0941-4355

Online Volltext: dx.doi.org/
Guberina, M.; Eberhardt, Wilfried; Stuschke, Martin; Gauler, Thomas; Cheufou, D.; Schuler, Martin; Stamatis, Georgios; Pöttgen, Christoph

Pretreatment metabolic volume in PET : Prognostic in lung cancer? German ESPATUE randomised phase3trial

In: Radiotherapy and Oncology (The Green Journal) Jg. 127 (2018) Nr. Suppl.1, S. S253 - S254

ISSN: 1879-0887; 0167-8140

Online Volltext: dx.doi.org/ (Open Access)
Oezkan, Filiz; Herold, Thomas; Darwiche, Kaid; Eberhardt, Wilfried; Worm, Karl; Christoph, Daniel; Wiesweg, Marcel; Freitag, Lutz; Schmid, Kurt Werner; Theegarten, Dirk; Hager, Thomas; Koenig, Michael J.; He, Kai; Taube, Christian; Schuler, Martin; Breitenbücher, Frank

Rapid and Highly Sensitive Detection of Therapeutically Relevant Oncogenic Driver Mutations in EBUS-TBNA Specimens From Patients With Lung Adenocarcinoma

In: Clinical Lung Cancer Jg. 19 (2018) Nr. 6, S. e879 - e884

ISSN: 1938-0690; 1525-7304

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Abu Jawad, Jehad; Gauler, Thomas; Guberina, M.; Darwiche, Kaid; Aigner, Clemens; Theegarten, Dirk; Schuler, Martin; Eberhardt, Wilfried; Stuschke, Martin

Sequential Dose Escalation Study NEOAHA for locally advanced NSCLC - Phase I-Results of Stage 1 (Integrated Boost-Radiation in neoadjuvant Therapy)

In: Strahlentherapie und Onkologie Jg. 194 (2018) Nr. Suppl. 1, S. S23 - S24

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/ (Open Access)
Joerger, M.; Soo, R. A.; Cho, B. C.; Navarro, A.; Sayehli, C. M.; Richly, Heike; Tai, D.; Kim, D. W.; Wolf, J.; Cassier, P.; Bender, S.; Ellinghaus, P.; Ince, S.; Rajagopalan, P.; Ocker, M.; Schuler, Martin

A novel mRNA-based patient selection strategy identifies fibroblast growth factor receptor (FGFR) inhibitor-sensitive tumors : Results from rogaratinib Phase-1 study

In: Annals of Oncology Jg. 28 (2017) Nr. Suppl. 5,

ISSN: 0923-7534; 1569-8041
Van Geel, Robin M. J. M.; Tabernero, Josep; Elez, Elena; Bendell, Johanna C.; Spreafico, Anna; Schuler, Martin; Yoshino, Takayuki; Delord, Jean-Pierre; Yamada, Yasuhide; Lolkema, Martijn P.; Faris, Jason E.; Eskens, Ferry A. L. M.; Sharma, Sunil; Yaeger, Rona; Lenz, Heinz-Josef; Wainberg, Zev A.; Avsar, Emin; Chatterjee, Arkendu; Jaeger, Savina; Tan, Eugene; Maharry, Kati; Demuth, Tim; Schellens, Jan H. M.

A phase Ib dose-escalation study of encorafenib and cetuximab with or without alpelisib in metastatic BRAF-mutant colorectal cancer

In: Cancer Discovery Jg. 7 (2017) Nr. 6, S. 610 - 619

ISSN: 2159-8290; 2159-8274

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Schadendorf, Dirk; Schuler, Martin

Checkpointinhibitoren

In: Der Onkologe Jg. 23 (2017) Nr. 8, S. 619 - 625

ISSN: 1433-0415; 0947-8965

Online Volltext: dx.doi.org/
Breitenbücher, Frank; Von Pawel, Joachim; Sebastian, Martin; Kortsik, Cornelius; Ting, Saskia; Kasper, Stefan; Wohlschläger, Jeremias; Worm, Karl; Morresi-Hauf, Alicia; Schad, Arno; Westerwick, Daniela; Wehler, Beatrice; Werner, Martin; Munzert, Gerd; Gaschler-Markefski, Birgit; Schmid, Kurt Werner; Schuler, Martin

Comprehensive biomarker analyses in patients with advanced or metastatic non-small cell lung cancer prospectively treated with the polo-like Kinase 1 Inhibitor BI2536

In: Oncology Research and Treatment Jg. 40 (2017) Nr. 7-8, S. 435 - 439

ISSN: 2296-5270; 0378-584X; 2296-5262; 1423-0240

Online Volltext: dx.doi.org/
Wieczorek, Sarah A.; Breitenbücher, Frank; Soni, Aashish; Paul-Konietzko, Katja; Ziegler, Sophie; Sak, Ali; Iliakis, George; Schuler, Martin

Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer

In: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 9, S. 1733 - 1744

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/
Al-Batran, S. E.; Pauligk, C.; Homann, N.; Schmalenberg, H.; Kopp, H. G.; Haag, G. M.; Luley, K.; Folprecht, G.; Probst, S.; Thuss-Patience, P.; Trojan, J.; Koenigsmann, M.; Lindig, U.; Pohl, M.; Kasper, Stefan; Hler, M. M.; Goetze, T.; Schuler, Martin; Jaeger, E.; Hofheinz, R. D.

Docetaxel, oxaliplatin, and fluorouracil/leucovorin (FLOT) for resectable esophagogastric cancer : Updated results from multicenter, randomized phase 3 FLOT4-AIO trial (German Gastric Group at AIO)

In: Annals of Oncology Jg. 28 5 (2017) -

ISSN: 0923-7534; 1569-8041
Wu, Yi-Long; Sequist, Lecia V; Hu, Cheng-Ping; Feng, Jifeng; Lu, Shun; Huang, Yunchao; Li, Wei; Hou, Mei; Schuler, Martin; Mok, Tony; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Hirsh, Vera; Gibson, Neil; Massey, Dan; Kim, Miyoung; Yang, James Chih-Hsin

EGFR mutation detection in circulating cell-free DNA of lung adenocarcinoma patients : analysis of LUX-Lung 3 and 6

In: British Journal of Cancer (BJC) Jg. 116 (2017) Nr. 2, S. 175 - 185

ISSN: 1532-1827; 0007-0920

Online Volltext: dx.doi.org/ (Open Access)
Nogova, Lucia; Sequist, Lecia V.; Garcia, Jose Manuel Perez; Andre, Fabrice; Delord, Jean-Pierre; Hidalgo, Manuel; Schellens, Jan H.M.; Cassier, Philippe A.; Camidge, D. Ross; Schuler, Martin; Vaishampayan, Ulka; Burris, Howard; Tian, G. Gary; Campone, Mario; Wainberg, Zev A.; Lim, Wan-Teck; LoRusso, Patricia; Shapiro, Geoffrey I.; Parker, Katie; Chen, Xueying; Choudhury, Somesh; Ringeisen, Francois; Graus-Porta, Diana; Porter, Dale; Isaacs, Randi; Buettner, Reinhard; Wolf, Jürgen

Evaluation of BGJ398, a Fibroblast growth factor receptor 1-3 kinase inhibitor, in patientswith advanced solid tumors harboring genetic alterations in fibroblast growth factor receptors : Results of a global phase I, dose-escalation and dose-expansion study

In: Journal of Clinical Oncology (JCO) Jg. 35 (2017) Nr. 2, S. 157 - 165

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Tureci, Özlem; Wiechen, Kai; Bazin, Igor; Maurus, Daniel; Schuler, Martin; Zvirbule, Zanete; Sahin, Ugur; Dhaene, Karl; Al-Batran, Salah-Eddin; Vynnychenko, Ihor; Melichar, Bohuslav; Rusyn, Andriy V.; Manikhas, Georgy; Dudov, Assen; Lordick, Florian

Expression of Claudin 18.2 and HER2 in gastric, gastroesophageal junction, and esophageal cancers : Results from the FAST study

In: Journal of Clinical Oncology (JCO) Jg. 35 (2017) S. 4038 - 4038

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schuler, Martin; Paz-Ares, L.; Sequist, L. V.; Tan, E. H.; Mok, T.; Hirsh, V.; O'Byrne, K.; Zhang, Lihua; Yamamoto, N.; Boyer, M.; Shah, R.; Bennouna, J.; Dickgreber, N. J.; De Greve, J.; Love, J.; Marten, A.; Fan, J.; Ehrnrooth, E.; Park, K.; Yang, JCH

First-line afatinib for advanced EGFR mutation-positive (EGFRm plus ) NSCLC : analysis of long-term responders in the Phase III LUX-Lung 3, 6 and 7 trials

In: Eur J Cancer Jg. 72 1 (2017) S. 176 - S177

ISSN: 0959-8049

Online Volltext: dx.doi.org/
Schuler, Martin; Paz-Ares, L.; Sequist, L. V.; Wu, Y. L.; Geater, S. L.; Marten, A.; Fandrey, Joachim; Park, K.; Yang, JCH

First-line afatinib for advanced EGFRm1 NSCLC : Analysis of long-term responders (LTRs) in the LUX-Lung (LL) 3, 6 and 7 trials

In: Ann Oncol Jg. 28 2 (2017) -

ISSN: 0923-7534; 1569-8041
Schuler, Martin; Paz-Ares, L.; Sequist, L. V.; Sebastian, M.; Wu, Y. L.; Geater, S. L.; Marten, A.; Fan, J.; Park, K.; Yang, JCH

First-line afatinib in patients with EGFR mutation-positive (EGFRm+) non-small-cell lung cancer (NSCLC) : analysis of long-term responders (LTRs) in the LUX-Lung 3, 6 and 7 trials

In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3: Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 172

ISSN: 2296-5270; 0378-584X; 2296-5262; 1423-0240

Online Volltext: dx.doi.org/
Hochmair, M.; Cappuzzo, F.; Tsai, C. M.; Schuler, Martin; Lam, K. C.; Stehle, G.; Cseh, A.; Lorence, R. M.; Linden, S.; Carriere, P.; Soo, R.

Global named patient use (NPU) program of afatinib in heavily pretreated advanced NSCLC patients who progressed following prior therapies, including erlotinib or gefitinib

In: Eur J Cancer Jg. 72 1 (2017) S. 183 - S184

ISSN: 0959-8049

Online Volltext: dx.doi.org/
Guberina, M.; Eberhardt, Wilfried; Stuschke, Martin; Gauler, Thomas; Heinzelmann, F.; Cheufou, D.; Kimmich, M.; Friedel, G.; Schmidberger, H.; Darwiche, Kaid; Jendrossek, Verena; Schuler, Martin; Stamatis, Georgios; Pöttgen, Christoph

Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer : secondary analysis of a randomized trial

In: Annals of Oncology Jg. 28 (2017) Nr. 5, S. 1084 - 1089

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Tewes, Mitra; Peis, Michael Wilhelm; Bogner, Simon; Theysohn, Jens; Reinboldt, Marcus Paul; Schuler, Martin; Welt, Anja

Hepatic arterial infusion chemotherapy for extensive liver metastases of breast cancer : efficacy, safety and prognostic parameters

In: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 10, S. 2131 - 2141

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/
Wiesweg, Marcel; Eberhardt, Wilfried; Reis, Henning; Ting, Saskia; Savvidou, Nikoleta; Skiba, Charlotte; Herold, Thomas; Christoph, Daniel; Meiler, Johannes; Worm, Karl; Kasper, Stefan; Theegarten, Dirk; Hense, Jörg; Hager, Thomas; Darwiche, Kaid; Oezkan, Filiz; Aigner, Clemens; Welter, Stefan; Kühl, Hilmar; Stuschke, Martin; Schmid, Kurt Werner; Schuler, Martin

High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung Cancer

In: Journal of Thoracic Oncology Jg. 12 (2017) Nr. 1, S. 54 - 64

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Okimoto, Ross A; Breitenbücher, Frank; Olivas, Victor R; Wu, Wei; Gini, Beatrice; Hofree, Matan; Asthana, Saurabh; Hrustanovic, Gorjan; Flanagan, Jennifer; Tulpule, Asmin; Blakely, Collin M; Haringsma, Henry J; Simmons, Andrew D; Gowen, Kyle; Suh, James; Miller, Vincent A; Ali, Siraj; Schuler, Martin; Bivona, Trever G.

Inactivation of Capicua drives cancer metastasis

In: Nature Genetics Jg. 49 (2017) Nr. 1, S. 87 - 96

ISSN: 1061-4036; 1546-1718

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Thress, Kenneth S.; Jacobs, Vivien; Angell, Helen K.; Yang, James Chih-Hsin; Sequist, Lecia V.; Blackhall, Fiona; Su, Wu-Chou; Schuler, Martin; Wolf, Jürgen; Gold, Kathryn A.; Cantarini, Mireille; Barrett, J. Carl; Jänne, Pasi A.

Modulation of Biomarker Expression by Osimertinib : Results of the Paired Tumor Biopsy Cohorts of the AURA Phase I Trial

In: Journal of Thoracic Oncology Jg. 12 (2017) Nr. 10, S. 1588 - 1594

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Kasper, Stefan; Reis, Henning; Ziegler, Sophie; Nothdurft, Silke; Mueller, Andre; Goetz, Moritz; Wiesweg, Marcel; Phasue, Jeannette; Ting, Saskia; Wieczorek, Sarah; Even, Anna; Worm, Karl; Pogorzelski, Michael; Breitenbuecher, Sandra; Meiler, Johannes; Paul, Andreas; Trarbach, Tanja; Schmid, Kurt Werner; Breitenbücher, Frank; Schuler, Martin

Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapy

In: OncoTarget Jg. 8 (2017) Nr. 28, S. 45898 - 45917

ISSN: 1949-2553

Online Volltext: dx.doi.org/ (Open Access)
Al-Batran, S. E.; Pauligk, C.; Homann, N.; Schmalenberg, H.; Kopp, H. G.; Haag, G. M.; Luley, K. B.; Schmiegel, W.; Folprecht, G.; Probst, S.; Prasnikar, N.; Thuss-Patience, P.; Fischbach, W.; Trojan, J.; Koenigsmann, M.; Goetze, T. O.; Kraus, T. W.; Battmann, A.; Moenig, S. P.; Bechstein, W.; Gaiser, T.; Tannapfel, A.; Jäger, E.; Schuler, Martin; Lindig, U.; Pohl, M.; Kasper, Stefan; Möhler, M.; Hofheinz, R. D.

Perioperative chemotherapy with docetaxel, oxaliplatin and fluorouracil/leucovorin (FLOT) versus epirubicin, cisplatin and fluorouracil or capecitabine (ECF/ECX) for resectable gastric or gastroesophageal junction (GEJ) adenocarcinoma (FLOT4-AIO) : a rando

In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3: Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 200 - 201

ISSN: 2296-5270; 2321-3575

Online Volltext: dx.doi.org/
Al-Batran, Salah-Eddin; Homann, Nils; Schmalenberg, Harald; Kopp, Hans-Georg; Haag, Georg Martin; Luley, Kim Barbara; Schmiegel, Wolff H.; Folprecht, Gunnar; Probst, Stephan; Prasnikar, Nicole; Thuss-Patience, Peter C.; Fischbach, Wolfgang; Trojan, Jorg; Koenigsmann, Michael; Pauligk, Claudia; Goetze, Thorsten Oliver; Jaeger, Elke; Meiler, Johannes; Schuler, Martin; Hofheinz, Ralf

Perioperative chemotherapy with docetaxel, oxaliplatin, and fluorouracil/leucovorin (FLOT) versus epirubicin, cisplatin, and fluorouracil or capecitabine (ECF/ECX) for resectable gastric or gastroesophageal junction (GEJ) adenocarcinoma (FLOT4-AIO) : A multicenter, randomized phase 3 trial

In: Journal of Clinical Oncology (JCO) Jg. 35 (2017) Nr. 15_suppl,

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schuler, Martin; Chan, S. L.; Yen, C.; Lin, C.; Choo, S. P.; Weiss, K.; Geier, A.; Okusaka, T.; Lim, H. Y.; Macarulla, T.; Zhu, A. X.; Kakizume, T.; Gu, Y.; Porta, D. G.; Myers, A. P.; Delord, J.

Phase I/II study of FGF401 in adult patients (pts) with hepatocellular carcinoma (HCC) or solid tumors and positive FGFR4/KLB expression

In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3, S. 234 - 235

ISSN: 2296-5270; 1538-7445

Online Volltext: dx.doi.org/
Sebastian, M.; Schuler, Martin; Schulz, C.; Deschler-Baier, B.; Kimmich, M.; Hilgert-Daute, K.; Griesinger, F.

Randomised Phase III study of osimertinib vs platinum-pemetrexed for EGFR T790M-positive advanced NSCLC (AURA3)

In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3: Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 170

ISSN: 2296-5270; 0378-584X; 2296-5262; 1423-0240

Online Volltext: dx.doi.org/
Oezkan, Filiz; Herold, Thomas; Darwiche, Kaid; Eberhardt, Wilfried; Christoph, Daniel; Worm, Karl; Freitag, Lutz; Schmid, Kurt Werner; Hager, Thomas; Breitenbücher, Frank; Schuler, Martin

Rapid and Highly Sensitive EGFRdelEx19 and KRAS Exon 2 Mutation Detection in EBUS-TBNA Specimen of Lung Adenocarcinoma

In: Journal of Thoracic Oncology Jg. 12 (2017) Nr. Suppl. 1, S. S1201 - S1201

ISSN: 1556-1380; 1556-0864
Scheulen, Max Ernst; Kaempgen, Eckhart; Keilholz, Ulrich; Heinzerling, Lucie; Ochsenreither, Sebastian; Abendroth, Annalena; Huger, Ralf A.; Grubert, Matthias; Wetter, Axel; Guberina, Nika; Bauer, Sebastian; Schuler, Gerold; Bornfeld, Norbert; Schuler, Martin; Richly, Heike

STREAM : A randomized discontinuation, blinded, placebo-controlled phase II study of sorafenib (5) treatment of chemonaive patients (pts) with metastatic uveal melanoma (MUM)

In: Journal of Clinical Oncology (JCO) Jg. 35 (2017) Nr. 15, S. 9511

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Kalkavan, Halime; Sharma, Piyush; Kasper, Stefan; Helfrich, Iris; Pandyra, Aleksandra A.; Gassa, Asmae; Virchow, Isabel; Flatz, Lukas; Brandenburg, Tim; Namineni, Sukumar; Heikenwalder, Mathias; Höchst, Bastian; Knolle, Percy A.; Wollmann, Guido; Von Laer, Dorothee; Drexler, Ingo; Rathbun, Jessica; Cannon, Paula M.; Scheu, Stefanie; Bauer, Jens; Chauhan, Jagat; Häussinger, Dieter; Willimsky, Gerald; Löhning, Max; Schadendorf, Dirk; Brandau, Sven; Schuler, Martin; Lang, Philipp A.; Lang, Karl S.

Spatiotemporally restricted arenavirus replication induces immune surveillance and type i interferon-dependent tumour regression

In: Nature Communications Jg. 8 (2017) S. 14447

ISSN: 2041-1723

Online Volltext: dx.doi.org/ (Open Access)
Sequist, L.; Wu, Y. L.; Schuler, Martin; Kato, T.; Yang, JCH; Tanaka, H.; Hida, T.; Lu, S.; Park, K.; Laurie, S.; Bennouna, J.; Sibilot, D. M.; Marten, A.; Peil, B.; Ehrnrooth, E.; Yamamoto, N.; Nakagawa, K.

Subsequent therapies post-afatinib among patients (pts) with EGFR mutation-positive (EGFRm plus ) NSCLC in LUX-Lung (LL) 3, 6 and 7

In: Ann Oncol Jg. 28 5 (2017) -

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Cappuzzo, Federico; Soo, Ross Andrew; Hochmair, Maximilian Johannes; Schuler, Martin; Mok, Tony Shu Kam; Stehle, Gerd; Cseh, Agnieszka; Lorence, Robert M..; Linden, Stephan; Forman, Nicole D.; Tsai, Chunming

1236P - Global named patient use (NPU) program of afatinib, an oral ErbB family blocker, in heavily pretreated advanced non-small cell lung carcinoma (NSCLC) patients who progressed following prior therapies, including erlotinib or gefitinib (E/G)

In: Annals of Oncology Jg. 27 (2016) Nr. Supplement 6, S. vi427

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/
Kim, Dong-Wan; Mehra, Ranee; Tan, Daniel S W; Felip, Enriqueta; Chow, Laura Q M; Camidge, D Ross; Vansteenkiste, Johan; Sharma, Sunil; De Pas, Tommaso; Riely, Gregory J; Solomon, Benjamin J; Wolf, Jürgen; Thomas, Michael; Schuler, Martin; Liu, Geoffrey; Santoro, Armando; Sutradhar, Santosh; Li, Siyu; Szczudlo, Tomasz; Yovine, Alejandro; Shaw, Alice T

Activity and safety of ceritinib in patients with ALK-rearranged non-small-cell lung cancer (ASCEND-1) : updated results from the multicentre, open-label, phase 1 trial

In: The Lancet Oncology Jg. 17 (2016) Nr. 4, S. 452 - 463

ISSN: 1470-2045; 1474-5488

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Fein, Luis; Wu, Yi-Long; Sequist, Lecia V; Geater, Sarayut L; Orlov, Sergey; Lee, Ki Hyeong; Tsai, Chun-Ming; Kato, Terufumi; Kiura, Katsuyuki; Barrios, Carlos H; Schuler, Martin; Hirsh, Vera; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Mok, Tony; Massey, Dan; Märten, Angela; Chih-Hsin Yang, James

Afatinib Versus Chemotherapy for EGFR Mutation-Positive NSCLC Patients Aged >=65 Years : Subgroup Analysis of LUX-Lung 3/6: P1.33: Track: Advanced NSCLC

In: Journal of Thoracic Oncology Jg. 11 (2016) Nr. 10 Supplement, S. 202 - S.203

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Yang, J C-H; Park, K; Kim, J-H; Bennouna, J; Chen, Y-M; Chouaid, C; De Marinis, F; Feng, J-F; Grossi, F; Kim, D-W; Liu, X; Lu, S; Strausz, J; Vinnyk, Y; Wiewrodt, R; Zhou, C; Wang, B; Chand, V K; Planchard, D; Ignatius Ou, Sai Hong; Planchard, David; Park, Keunchil; Schuler, Martin; Yang, James; Chand, Vikram; Rohr, Klaus; Bagnes, Claudia; Martin, Claudio Marcelo; Recondo, Gonzalo; Zarba, Juan Jose; Blajman, Cesar; Richardet, Martín; McLachlan, Sue-Anne; Parente, Phillip; Underhill, Craig; Crombie, Catherine; Mainwaring, Paul; Greil, Richard; Humblet, Yves; Bustin, Frédérique; Carestia, Luciano; Galdermans, Danny; Lambrechts, Marc; Delval, Laetitia; Vercauter, Piet; Zhou, Caicun; Wang, Jin; Huang, Cheng; Lin, Xiaoyan; Wu, Yilong; Liu, Xiaoqing; Cheng, Ying; Qin, Shukui; Feng, Jifeng; Huang, Jianjin; Zhang, Yiping; Lu, Shun; Zereu, Manuela; Garicochea, Bernardo; Zadra, Cyntia Albuquerque; Riska, Henrik; Alanko, Tuomo; Cadranel, Jacques; Chouaid, Christos; Zalcman, Gérard; Sibilot, Denis Moro; Perol, Maurice; Planchard, David; Bennouna, Jaafar; Fournel, Pierre; Gervais, Radj; Rotarski, Maciej; Coudert, Bruno; Schuler, Martin; Thomas, Michael; Wehler, Thomas; Faehling, Martin; Keilholz, Ulrich; Laack, Eckart; von Pawel, Joachim; Huber, Rudolf; Dickgreber, Nicolas; Wiewrodt, Rainer; Mark, Zsuzsanna; Tehenes, Sandor; Strausz, Janos; Sarosi, Veronika; Prabhash, Kumar; Jain, Minish; Venkatesan, Srinivasan; Sharma, Lalit; Dadhich, Hemant; Nagarkar, Rajnish Vasant; Onn, Amir; Gottfried, Maya; Stemmer, Solomon; Migliorino, Maria Rita; Grossi, Francesco; Bidoli, Paolo; Bearz, Alessandra; Gridelli, Cesare; Milandri, Carlo; Platania, Marco; Ceresoli, Giovanni Luca; Cruciani, Giorgio; Delgado, Francisco Gutierrez; Gonzalez Perez, José Luis; Luna, Gabriela Alvarado; Baca, Othon Padilla; Aerts, J G J V; Stigt, J A; Dingemans, A M C; Herder, G J M; Gans, S J M; Salas Sánchez, Jorge Fernando; Alvarez Barreda, Renzo Luzgardo; Pantigoso, Wilbert Rodriguez; Palomino, Osbert Luis Mejia; Jaskiewicz, Piotr; Kazarnowicz, Andrzej; Serwatowski, Piotr; Szczesna, Aleksandra; Jassem, Jacek; Lubennikov, Vladimir; Karaseva, Nina; Orlov, Sergey; Ragulin, Yuri; Garrido, Pilar; González Larriba, José Luis; Camps, Carlos; Campelo, Rosario García; Lianes, Pilar; Cobo, Manuel; Felip, Enriqueta; Kim, Dong-Wan; Kim, Sang-We; Park, Keunchil; Kim, Joo-Hang; Han, Ji-Youn; Kim, Young-Chul; Yang, Chih-Hsin; Hsia, Te-Chun; Chen, Yuh-Min; Tsai, Ying-Huang; Chang, Gee-Chen; Tsao, Thomas Chang-Yao; Su, Wu-Chou; Huang, Ming-Shyan; Ho, Ching-Liang; Hsieh, Ruey-Kuen; Vinnyk, Yuriy; Popovych, Oleksandr; Ponomarova, Olga; Bondarenko, Igor; Polishchuk, Iryna; Shah, Riyaz; Mitra, Sanka; Popat, Sanjaykumar; Spicer, James; Toy, Elizabeth; Popat, Sanjaykumar; Talbot, Toby; Brown, Emma; Upadhyay, Sunil; Summers, Yvonne; Gurtler, Jayne; Meza, Luis; Thropay, John

Afatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib : phase III randomized LUX-Lung 5 trial

In: Annals of Oncology Jg. 27 (2016) Nr. 3, S. 417 - 423

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/ (Open Access)
Reimer, P.; Höhler, T.; Schuler, Martin; Markus, P.; Knipp, Heike; Schumacher, B.; Dechene, Alexander; Ting, Saskia; Kasper, S.; Meiler, Johannes; Kostbade, K.; Berger, W.; Herold, T.; Trarbach, Tanja; Linden, G.; Steinmetz, H.T.; Schmid, Kurt Werner; Worm, K.; Paul, A.

Cetuximab biweekly (q2w) plus mFOLFOX6 as 1st line therapy in patients (pts) with KRAS wild-type (wt) (exon 2) metastatic colorectal cancer (mCRC) – Primary endpoint and subgroup analysis of the CEBIFOX trial

In: Annals of Oncology Jg. 27 (2016) Nr. Suppl.6, S. 508P

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/
Nel, Ivonne; Gauler, Thomas; Bublitz, Kira; Lazaridis, Lazaros; Goergens, André; Giebel, Bernd; Schuler, Martin; Hoffmann, Andreas-Claudius

Circulating Tumor Cell Composition in Renal Cell Carcinoma

In: PLoS ONE Jg. 11 (2016) Nr. 4, S. e0153018

ISSN: 1932-6203

Online Volltext: dx.doi.org/ (Open Access)
Köhler, Jens; Schuler, Martin; Gauler, Thomas; Nöpel-Dünnebacke, Stefanie; Ahrens, Maike; Hoffmann, Andreas-Claudius; Kasper, Stefan; Nensa, Felix; Gomez, Benedikt; Hahnemann, Maria; Breitenbücher, Frank; Cheufou, Danjouma; Özkan, Filiz; Darwiche, Kaid; Hoiczyk, Mathias; Reis, Henning; Welter, Stefan; Eberhardt, Wilfried; Eisenacher, Martin; Teschler, Helmut; Stamatis, Georgios; Schmiegel, Wolff; Hahn, Stephan Albrecht; Baraniskin, Alexander

Circulating U2 small nuclear RNA fragments as a diagnostic and prognostic biomarker in lung cancer patients

In: Journal of Cancer Research and Clinical Oncology Jg. 142 (2016) Nr. 4, S. 795 - 805

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/
Tabernero, J.; van Geel, R.; Guren, T.; Yaeger, R.; Spreafico, A.; Faris, J.; Yoshino, T.; Yamada, Y.; Tae, W. K.; Bendell, J.; Schuler, Martin; Lenz, H. J.; Eskens, F.; Desai, J.; Hochster, H.; Avsar, E.; Demuth, T.; Sandor, V.; Elez, E.; Schellens, J.

Combination of encorafenib and cetuximab with or without alpelisib in patients with advanced BRAF-mutant colorectal cancer (BRAFm CRC) : phase 2 results

In: Annals of Oncology Jg. 27 (2016) Nr. Suppl. 2, S. ii127 - ii128

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Stang, Andreas; Jöckel, Karl-Heinz; Kühl, Hilmar; Darwiche, Kaid; Schuler, Martin; Kowall, Bernd

Concluding remarks : [Korrespondenz zu "Lung Cancer Screening Using Low Dose CT Scanning in Germany by Prof. Dr. med. Andreas Stang, MPH, Prof. Dr. med. Martin Schuler, Dr. rer. nat. Dr. rer. san. Bernd Kowall, Dr. med. Kaid Darwiche, PD Dr. med. Hilmar Kühl, and Prof. Dr. rer. nat. Karl-Heinz Jöckel in issue 38/2015"]

In: Deutsches Ärzteblatt international Jg. 113 (2016) Nr. 17, S. 297 - 298

ISSN: 1866-0452

Online Volltext: dx.doi.org/ (Open Access)
Stintzing, S.; Modest, D. P.; Jung, A.; Kirchner, T.; Schafer, R.; Sers, C.; Hildebrandt, B.; Daum, S.; Folprecht, G.; Schuler, Martin; Kasper, Stefan; Trojan, J.; Jaeger, D.; Schulze-Bergkamen, H.; von Weikersthal, L. F.; Schalhorn, A.; Heinemann, V.

Differences in gene-expression in mCRC tissue samples with regard to tumor location and used chemotherapeutic substances : Data of the FIRE-1 study

In: Journal of Clinical Oncology (JCO) Jg. 34 (2016) Nr. Suppl. 4, S. 562

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Yang, J C-H; Sequist, L V; Zhou, C; Schuler, Martin; Geater, S L; Mok, T; Hu, C-P; Yamamoto, N; Feng, J; O'Byrne, K; Lu, S; Hirsh, V; Huang, Y; Sebastian, M; Okamoto, I; Dickgreber, N; Shah, R; Märten, A; Massey, D; Wind, S; Wu, Y-L

Effect of dose adjustment on the safety and efficacy of afatinib for EGFR mutation-positive lung adenocarcinoma : post hoc analyses of the randomized LUX-Lung 3 and 6 trials

In: Annals of Oncology Jg. 27 (2016) Nr. 11, S. 2103 - 2110

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Sequist, Lecia; Popat, Sanjay; Mok, Tony; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Hirsh, Vera; Wu, Yi-Long

First-Line Afatinib versus Chemotherapy in Patients with Non-Small Cell Lung Cancer and Common Epidermal Growth Factor Receptor Gene Mutations and Brain Metastases

In: Journal of Thoracic Oncology Jg. 11 (2016) Nr. 3, S. 380 - 390

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Stang, Andreas; Kowall, Bernd; Schuler, Martin; Jöckel, Karl-Heinz

Früherkennung von Lungenkrebs : Low-dose-Computertomographie-Screening

In: Der Onkologe Jg. 22 (2016) Nr. 8, S. 568 - 577

ISSN: 1433-0415; 0947-8965

Online Volltext: dx.doi.org/
Al-Batran, Salah-Eddin; Hofheinz, Ralf D; Pauligk, Claudia; Kopp, Hans-Georg; Haag, Georg Martin; Luley, Kim Barbara; Meiler, Johannes; Homann, Nils; Lorenzen, Sylvie; Schmalenberg, Harald; Probst, Stephan; Koenigsmann, Michael; Egger, Matthias; Prasnikar, Nicole; Caca, Karel; Trojan, Jörg; Martens, Uwe M; Block, Andreas; Fischbach, Wolfgang; Mahlberg, Rolf; Clemens, Michael; Illerhaus, Gerald; Zirlik, Katja; Behringer, Dirk M; Schmiegel, Wolff; Pohl, Michael; Heike, Michael; Ronellenfitsch, Ulrich; Schuler, Martin; Bechstein, Wolf O; Königsrainer, Alfred; Gaiser, Timo; Schirmacher, Peter; Hozaeel, Wael; Reichart, Alexander; Goetze, Thorsten O; Sievert, Mark; Jäger, Elke; Mönig, Stefan; Tannapfel, Andrea

Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO

In: The Lancet Oncology Jg. 17 (2016) Nr. 12, S. 1697 - 1708

ISSN: 1470-2045; 1474-5488

Online Volltext: dx.doi.org/
Al-Batran, S. E.; Schuler, Martin; Zvirbule, Z.; Manikhas, G.; Lordick, F.; Tureci, O.; Huber, C.; Sahin, U.

IMAB362 : a novel immunotherapeutic antibody targeting the tight-junction protein component CLAUDIN18.2 in gastric cancer

In: Annals of Oncology Jg. 27 (2016) Nr. Suppl. 2, S. ii141 - ii142

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Barrios, Carlos H; Wu, Yi-Long; Chih-Hsin Yang, James; Sequist, Lecia V; Geater, Sarayut L; Mok, Tony; Hu, Cheng-Ping; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Lu, Shun; Hirsh, Vera; Sebastian, Martin; Okamoto, Isamu; Shah, Riyaz; Märten, Angela; Massey, Dan; Wind, Sven; Schuler, Martin

Impact of Dose Adjustment on Afatinib Safety and Efficacy in EGFR Mutation-Positive NSCLC: Post-Hoc Analyses of LUX-Lung 3/6: Track: Advanced NSCLC

In: Journal of Thoracic Oncology Jg. 11 (2016) Nr. 10 Supplement, S. 210 - S. 211

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Yang, J; Sequist, L V; Yamamoto, N; Zhou, C; O'Byrne, K; Hirsh, V; Mok, T; Shah, R; Wu, Y-L

Impact of dose adjustment on the safety and efficacy of afatinib in patients (pts) with advanced EGFR mutation-positive non-small cell lung cancer (NSCLC): Post-hoc analyses of LUX-Lung 3 (LL3) and LUX-Lung 6 (LL6) : 138PD

In: Journal of Thoracic Oncology Jg. 11 (2016) Nr. Suppl. 4, S. 116 - 117

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Falkenhorst, Johanna; Grunewald, Susanne; Mühlenberg, Thomas; Marino-Enriquez, Adrian; Reis, Anna-Carina; Corless, Christopher; Heinrich, Michael; Treckmann, Jürgen-Walter; Podleska, Lars; Schuler, Martin; Fletcher, Jonathan Alfred; Bauer, Sebastian

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

In: OncoTarget Jg. 7 (2016) Nr. 27, S. 41390 - 41403

ISSN: 1949-2553

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Yang, J. C.-H.; Planchard, D.

Reply to the letter to the editor ‘What is the clinical impact of the LUX-Lung 5 trial?’ by Addeo

In: Annals of Oncology Jg. 27 (2016) Nr. 6, S. 1172 - 1173

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Hoya, V.; Stuschke, Martin; Sauerwein, Wolfgang; Bornfeld, Norbert; Metz, Klaus; Schuler, Martin; Kasper, Stefan

Small cell neuroendocrine carcinoma of the right eye : A case report

In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 189 - 189

ISSN: 2296-5270
Joerger, M.; Soo, R.; Cho, B.C.; Mendivil, A. Navarro; Sayehli, C.; Richly, Heike; Tai, D.; Kim, D.-W.; Wolf, J.; Cassier, P.; Ellinghaus, P.; Hildebrandt, S.; Behre, S.; Helmbrecht, C.; Kerpen, S.; Zielinski, D.; Ince, S.; Rajagopalan, P.; Ocker, M.; Schuler, Martin

developmental therapeuticsPhase I study of the pan-fibroblast growth factor receptor (FGFR) inhibitor BAY 1163877 with expansion cohorts for subjects based on tumor FGFR mRNA expression levels

In: Annals of Oncology Jg. 27 (2016) Nr. Suppl. 6, 360O_PR

ISSN: 1569-8041; 1569-8041

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Abu Jawad, Jehad; Gkika, Eleni; Freitag, Lutz; Lübcke, Wolfgang; Welter, Stefan; Gauler, Thomas; Schuler, Martin; Eberhardt, Wilfried; Stamatis, Georgios; Stuschke, Martin

Accelerated radiotherapy and concurrent chemotherapy for patients with contralateral central or mediastinal lung cancer relapse after pneumonectomy

In: Journal of Thoracic Disease Jg. 7 (2015) Nr. 3, S. 264 - 272

ISSN: 2072-1439

Online Volltext: dx.doi.org/
Wu, Y. L.; Sequist, L. V.; Geater, S. L.; Orlov, S.; Lee, K. H.; Tsai, C. M.; Kato, T.; Kiura, K.; Barrios, C. H.; Schuler, Martin; Hirsh, V.; Yamamoto, N.; OByrne, K.; Mok, T.; Massey, D.; Marten, A.; Yang, J. C. H.

Afatinib (A) versus chemotherapy (CT) for EGFR mutation-positive NSCLC patients (pts) aged ≥65 years : Subgroup analyses of LUX-Lung 3 (LL3) and LUX-Lung 6 (LL6)

In: Annals of Oncology Jg. 26 (2015) Nr. S 9: ESMO Asia Congress, 18-21 December 2015, Singapore : Submitted Abstracts, S. 136 - 137

ISSN: 0923-7534; 1569-8041
Schuler, Martin; Yang, J. C. H.; Park, K.; Chand, V. K.; Wang, B.; Planchard, D.

Afatinib (a) plus paclitaxel (p) following progression on a monotherapy in patients (pts) with metastatic non-small-cell lung cancer (nsclc) who previously benefited from erlotinib (e)/gefitinib (g) : a global randomised phase iii triallux-lung 5 (ll5)

In: Annals of Oncology Jg. 26 (2015) Nr. S 1, S. i33 - i34

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Yang, James Chih-Hsin; Wu, Yi-Long; Schuler, Martin; Sebastian, Martin; Popat, Sanjay; Yamamoto, Nobuyuki; Zhou, Caicun; Hu, Cheng-Ping; O'Byrne, Kenneth; Feng, Jifeng; Lu, Shun; Huang, Yunchao; Geater, Sarayut L; Lee, Kye Young; Tsai, Chun-Ming; Gorbunova, Vera; Hirsh, Vera; Bennouna, Jaafar; Orlov, Sergey; Mok, Tony; Boyer, Michael; Su, Wu-Chou; Lee, Ki Hyeong; Kato, Terufumi; Massey, Dan; Shahidi, Mehdi; Zazulina, Victoria; Sequist, Lecia V

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6) : analysis of overall survival data from two randomised, phase 3 trials

In: The Lancet Oncology Jg. 16 (2015) Nr. 2, S. 141 - 151

ISSN: 1474-5488; 1470-2045

Online Volltext: dx.doi.org/
Breitenbücher, Frank; Schuler, Martin; Markova, Boyka

Alternative tumor suppressor mechanisms in lung carcinomas - modulation of senescence by growth factor-induced signaling

In: Cancer Research Jg. 75 (2015) Nr. 15 Suppl., S. 1033

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Richly, Heike; Kim, Tae Min; Schuler, Martin; Kim, Dong-Wan; Harrison, Simon J.; Shaw, Alice T.; Boral, Anthony L.; Yovine, Alejandro; Solomon, Benjamin

Ceritinib in patients with advanced anaplastic lymphoma kinase-rearranged anaplastic large-cell lymphoma

In: Blood Jg. 126 (2015) Nr. 10, S. 1257 - 1258

ISSN: 1528-0020; 0006-4971

Online Volltext: dx.doi.org/
Kasper, Stefan; Meiler, Johannes; Knipp, Heike; Hoehler, Thomas; Reimer, Peter; Steinmetz, Tilman; Berger, Winfried; Linden, Gabriele; Ting, Saskia; Markus, Peter; Paul, Andreas; Dechene, Alexander; Schumacher, Brigitte; Kosbade, Karina; Worm, Karl; Schmid, Kurt Werner; Herold, Thomas; Schuler, Martin; Trarbach, Tanja

Cetuximab biweekly plus mFOLFOX6 as first-line therapy in patients (pts) with KRAS wild-type (wt) (exon 2) metastatic colorectal cancer (mCRC) : Primary endpoint and subgroup analysis of the CEBIFOX trial

In: Journal of Clinical Oncology (JCO) Jg. 33 (2015) Nr. 15 Suppl., S. 3568

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Yang, James C.-H.; Sequist, Lecia V.; Geater, Sarayut Lucien; Tsai, Chun-Ming; Mok, Tony Shu Kam; Schuler, Martin; Yamamoto, Nobuyuki; Yu, Chong-Jen; Ou, Sai-Hong I.; Zhou, Caicun; Massey, Daniel; Zazulina, Victoria; Wu, Yi-Long

Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations : A combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6

In: The Lancet Oncology Jg. 16 (2015) Nr. 7, S. 830 - 838

ISSN: 1474-5488

Online Volltext: dx.doi.org/
George, Julie; Lim, Jing Shan; Jang, Se Jin; Cun, Yupeng; Ozretia, Luka; Kong, Gu; Leenders, Frauke; Lu, Xin; Fernández-Cuesta, Lynnette; Bosco, Graziella; Müller, Christian; Dahmen, Ilona; Jahchan, Nadine S.; Park, Kwon-Sik; Yang, Dian; Karnezis, Anthony N.; Vaka, Dedeepya; Torres, Angela; Wang, Maia Segura; Korbel, Jan O.; Menon, Roopika; Chun, Sung-Min; Kim, Deokhoon; Wilkerson, Matt; Hayes, Neil; Engelmann, David; Pützer, Brigitte; Bos, Marc; Michels, Sebastian; Vlasic, Ignacija; Seidel, Danila; Pinther, Berit; Schaub, Philipp; Becker, Christian; Altmüller, Janine; Yokota, Jun; Kohno, Takashi; Iwakawa, Reika; Tsuta, Koji; Noguchi, Masayuki; Muley, Thomas; Hoffmann, Hans; Schnabel, Philipp A.; Petersen, Iver; Chen, Yuan; Soltermann, Alex; Tischler, Verena; Choi, Chang-Min; Kim, Yong-Hee; Massion, Pierre P.; Zou, Yong; Jovanovic, Dragana; Kontic, Milica; Wright, Gavin M.; Russell, Prudence A.; Solomon, Benjamin; Koch, Ina; Lindner, Michael; Muscarella, Lucia A.; La Torre, Annamaria; Field, John K.; Jakopovic, Marko; Knezevic, Jelena; Castaños-Vélez, Esmeralda; Roz, Luca; Pastorino, Ugo; Brustugun, Odd-Terje; Lund-Iversen, Marius; Thunnissen, Erik; Köhler, Jens; Schuler, Martin; Botling, Johan; Sandelin, Martin; Sanchez-Cespedes, Montserrat; Salvesen, Helga B.; Achter, Viktor; Lang, Ulrich; Bogus, Magdalena; Schneider, Peter M.; Zander, Thomas; Ansén, Sascha; Hallek, Michael; Wolf, Jürgen; Vingron, Martin; Yatabe, Yasushi; Travis, William D.; Nürnberg, Peter; Reinhardt, Christian; Perner, Sven; Heukamp, Lukas; Büttner, Reinhard; Haas, Stefan A.; Brambilla, Elisabeth; Peifer, Martin; Sage, Julien; Thomas, Roman K.

Comprehensive genomic profiles of small cell lung cancer

In: Nature Jg. 524 (2015) Nr. 7563, S. 47 - 53

ISSN: 0028-0836; 1476-4687

Online Volltext: dx.doi.org/ (Open Access)
Tewes, Mitra; Kasimir-Bauer, Sabine; Welt, Anja; Schuler, Martin; Kimmig, Rainer; Aktas, Bahriye

Detection of disseminated tumor cells in bone marrow and circulating tumor cells in blood of patients with early-stage male breast cancer

In: Journal of Cancer Research and Clinical Oncology Jg. 141 (2015) Nr. 1, S. 87 - 92

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/
Jaeger, Savina; Spreafico, Anna; van Geel, Robin; Bendell, Johanna C.; Lolkema, Martijn P.; Tabernero, Josep; Lenz, Heinz-Josef; Schellens, Jan H. M.; Avsar, Emin; Wainberg, Zev A.; Yoshino, Takayuki; Eskens, Ferry A. L. M.; Sharma, Sunil; Delord, Jean-Pierre; Schuler, Martin; Chatterjee, Arkendu; Faris, Jason E.; Yaeger, Rona; Demuth, Tim; Yamada, Yasuhide

Final biomarker analysis of the phase I study of the selective BRAF V600 inhibitor encorafenib (LGX818) combined with cetuximab with or without the α-specific PI3K inhibitor alpelisib (BYL719) in patients with advanced BRAF-mutant colorectal cancer

In: Cancer Research Jg. 75 (2015) Nr. 15 Suppl., S. CT136

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Reis, Henning; Herold, Thomas; Ting, S.; Worm, Karl Heinz; Huber, U.; Christoph, Daniel; Eberhardt, Wilfried; Kostbade, K.; Kasper, Stefan; Stamatis, Georgios; Welter, Stefan; Darwiche, Kaid; Karpf-Wissel, Rüdiger; Theegarten, Dirk; Schmidt, K. W.; Schuler, Martin; Wiesweg, Marcel

HER2 expression and markers of phosphoinositide-3-kinase pathway activation define a favorable subgroup of metastatic pulmonary adenocarcinomas

In: Lung Cancer Jg. 88 (2015) Nr. 1, S. 34 - 41

ISSN: 0169-5002

Online Volltext: dx.doi.org/
Passaro, A.; Yang, J. C.; Ahn, M.; Dickgreber, N. J.; Halmos, B.; Hirsh, V.; Hochmair, M. J.; Levy, B. P.; de Marinis, F.; Mok, T.; OByrne, K.; Okamoto, I.; Schuler, Martin; Sebastian, M.; Shah, R.; Tan, E.; Yamamoto, N.; Marten, A.; Wind, S.; Carbone, D. P.

Influence of dose adjustment on afatinib safety and efficacy in patients (pts) with advanced EGFR mutation-positive (EGFRm plus ) non-small cell lung cancer (NSCLC)

In: Annals of Oncology Jg. 26 (2015) Nr. S 6, S. vi73 - vi89

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Yang, James Chih-Hsin; Ahn, Myung-Ju; Dickgreber, Nicolas J.; Halmos, Balazs; Hirsh, Vera; Hochmair, Maximilian J.; Levy, Benjamin Philip; De Marinis, Filippo; Mok, Tony; O´Byrne, Kenneth; Okamoto, Isamu; Schuler, Martin; Sebastian, Martin; Shah, Riyaz N. H; Tan, Eng-Huat; Yamamoto, Nobuyuki; Marten, Angela; Massey, Dan; Wind, Sven; Carbone, David Paul

Influence of dose adjustment on afatinib safety and efficacy in patients (pts) with advanced EGFR mutation-positive (EGFRm plus ) non-small cell lung cancer (NSCLC)

In: Journal of Clinical Oncology Jg. 33 (2015) Nr. 15_suppl, S. 8073

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ Online Volltext
Mühlenberg, Thomas; Grunewald, Susanne; Treckmann, Jürgen-Walter; Podleska, Lars; Schuler, Martin; Fletcher, Jonathan A.; Bauer, Sebastian

Inhibition of KIT-Glycosylation by 2-Deoxyglucose Abrogates KIT-Signaling and Combination with ABT-263 Synergistically Induces Apoptosis in Gastrointestinal Stromal Tumor

In: PLoS ONE Jg. 10 (2015) Nr. 3, S. e0120531

ISSN: 1932-6203

Online Volltext: dx.doi.org/ (Open Access)
Stang, Andreas; Schuler, Martin; Kowall, Bernd; Darwiche, Kaid; Kühl, Hilmar; Jöckel, Karl-Heinz

Lungenkrebsscreening mit Low-Dose-Computertomographie in Deutschland : Hochrechnung der Kennzahlen des National Lung Screening Trial

In: Deutsches Ärzteblatt international Jg. 112 (2015) Nr. 38, S. 637 - 644

ISSN: 1866-0452

Online Volltext: dx.doi.org/ (Open Access)
Pogorzelski, M.; Ting, Saskia; Gauler, Thomas; Breitenbücher, Frank; Vossebein, I.; Hoffarth, S.; Markowetz, J.; Lang, Stephan; Bergmann, Christoph; Brandau, Sven; Abu-Jawad, J.; Schmid, Kurt Werner; Schuler, Martin; Kasper, Stefan

Molecular dissection of the impact of frequent genetic alterations on the response of head and neck cancers to anti-epidermal growth factor receptor-directed therapies

In: Oral Oncology Jg. 51 (2015) Nr. 5, S. e39

ISSN: 1879-0593; 1368-8375

Online Volltext: dx.doi.org/
Wu, Y. L.; Sequist, L. V.; Schuler, Martin; Yamamoto, N.; Zhou, C.; Hu, C. P.; OByrne, K.; Hirsh, V.; Mok, T.; Zazulina, V.; Yang, J. C. H.

Overall survival (OS) with afatinib (A) vs chemotherapy (CT) in patients (pts) with NSCLC harboring EGFR mutations (mut) : Subgroup analyses by race in LUX-Lung 3 (LL3) and LUX-Lung 6 (LL6)

In: Annals of Oncology Jg. 26 (2015) Nr. S 9: ESMO Asia Congress, 18-21 December 2015, Singapore : Submitted Abstracts, S. 136

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Janku, F.; Juric, D.; Cortes, J.; Rugo, H.; Burris, H. A.; Schuler, Martin; Deschler-Baier, B.; Middleton, M. R.; Gil-Martin, M.; Berlin, J.; Winer, E.; Bootle, D.; Blumenstein, L.; Demanse, D.; Coughlin, C.; Quadt, C.; Baselga, J.

Phase I study of the PI3K alpha inhibitor BYL719 plus fulvestrant in patients with PIK3CA-altered and wild type ER+/HER2-locally advanced or metastatic breast cancer

In: Cancer Research Jg. 75 (2015) Nr. S 9, S. 9 - 13

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Eberhardt, Wilfried; Pöttgen, Christoph; Gauler, Thomas; Friedel, Godehard; Veit, Stefanie; Heinrich, Vanessa; Welter, Stefan; Budach, Wilfried; Spengler, Werner; Kimmich, Martin; Fischer, Berthold; Schmidberger, Heinz; De Ruysscher, Dirk; Belka, Claus; Cordes, Sebastian; Hepp, Rodrigo; Lütke-Brintrup, Diana; Lehmann, Nils; Schuler, Martin; Jöckel, Karl-Heinz; Stamatis, Georgios; Stuschke, Martin

Phase III Study of Surgery Versus Definitive Concurrent Chemoradiotherapy Boost in Patients With Resectable Stage IIIA(N2) and Selected IIIB Non-Small-Cell Lung Cancer After Induction Chemotherapy and Concurrent Chemoradiotherapy (ESPATUE)

In: Journal of Clinical Oncology (JCO) Jg. 33 (2015) Nr. 35, S. 4194 - 4201

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Bauer, Sebastian; Herold, Thomas; Mühlenberg, Thomas; Reis, Anna-Carina; Falkenhorst, Johanna; Backs, Miriam; Ketzer, Julia; Breitenbücher, Frank; Schuler, Martin; Grunewald, Susanne

Plasma sequencing to detect a multitude of secondary KIT resistance mutations in metastatic gastrointestinal stromal tumors (GIST)

In: Journal of Clinical Oncology (JCO) Jg. 33 (2015) Nr. 15_suppl, S. 10518

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ Online Volltext
Pöttgen, Christoph; Stuschke, Martin; Graupner, Britta; Theegarten, Dirk; Gauler, Thomas; Jendrossek, Verena; Freitag, Lutz; Abu Jawad, Jehad; Gkika, Eleni; Wohlschläger, Jeremias; Welter, Stefan; Hoiczyk, Matthias; Schuler, Martin; Stamatis, Georgios; Eberhardt, Wilfried

Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors

In: BMC Cancer Jg. 15 (2015) Nr. 1, S. 363

ISSN: 1471-2407

Online Volltext: dx.doi.org/ (Open Access)
Gautschi, Oliver; Bluthgen, Marie-Virginia; Smit, Egbert F.; Wolf, Jürgen; Früh, Martin; Petersenn, Stephan; Schuler, Martin; Zalcman, Gérard; Milia, Julie; Mazieres, Julien

Targeted Therapy for Patients with BRAF-Mutant Lung Cancer : Results from the European EURAF Cohort

In: Annals of Oncology Jg. 26 (2015) Nr. S 1: European Lung Cancer Conference (ELCC), Geneva, Switzerland, 15-18 April 2015 : Abstracts, S. i61

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Gautschi, Oliver; Milia, Julie; Cabarrou, Bastien; Bluthgen, Marie-Virginia; Besse, Benjamin; Smit, Egbert F.; Wolf, Jürgen; Peters, Solange; Früh, Martin; Koeberle, Dieter; Oulkhouir, Youssouf; Schuler, Martin; Curioni-Fontecedro, Alessandra; Huret, Benjamin; Kerjouan, Mallorie; Michels, Sebastian; Pall, Georg; Rothschild, Sacha I.; Schmid-Bindert, Gerald; Scheffler, Matthias; Veillon, Rémi; Wannesson, Luciano; Diebold, Joachim; Zalcman, Gérard; Filleron, Thomas; Mazières, Julien

Targeted Therapy for Patients with BRAF-Mutant Lung Cancer Results from the European EURAF Cohort

In: Journal of Thoracic Oncology Jg. 10 (2015) Nr. 10, S. 1451 - 1457

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Hyman, David M.; Puzanov, Igor; Subbiah, Vivek; Faris, Jason E.; Chau, Ian; Blay, Jean‑Yves; Wolf, Jürgen; Raje, Noopur S.; Diamond, Eli L.; Hollebecque, Antoine; Gervais, Radj; Elez‑Fernandez, Maria Elena; Italiano, Antoine; Hofheinz, Ralf‑Dieter; Hidalgo, Manuel; Chan, Emily; Schuler, Martin; Lasserre, Susan Frances; Makrutzki, Martina; Sirzen, Florin; Veronese, Maria Luisa; Tabernero, Josep; Baselga, José

Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations

In: The New England Journal of Medicine Jg. 373 (2015) Nr. 8, S. 726 - 736

ISSN: 1533-4406; 0028-4793

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Hoffmann, Gesine; Breitenbücher, Frank; Schuler, Martin; Ehrenhofer-Murray, Ann

A Novel Sirtuin 2 (SIRT2) Inhibitor with p53-dependent Pro-apoptotic Activity in Non-small Cell Lung Cancer

In: The Journal of Biological Chemistry (JBC) Jg. 289 (2014) Nr. 8, S. 5208 - 5216

ISSN: 0021-9258; 1083-351X

Online Volltext: dx.doi.org/
Wiesweg, M; Aydin, S; Köninger, Angela; Stein, Anja; Schara, Ulrike; van Roye, C; Hense, Jörg; Welt, Anja; Schuler, Martin

Administration of Gemcitabine for Metastatic Adenocarcinoma during Pregnancy : A Case Report and Review of the Literature

In: AJP Reports Jg. 4 (2014) Nr. 1, S. 017 - 022

ISSN: 2157-6998

Online Volltext: dx.doi.org/ (Open Access)
Christoph, Daniel; Reyna-Asuncion, Bernadette; Hassan, Biftu; Tran, Cindy; Maltzman, Julia D; O'Shannessy, Daniel J; Gauler, Thomas; Wohlschläger, Jeremias; Schuler, Martin; Eberhardt, Wilfried; Hirsch, Fred R

Assessment of Folate Receptor-α and Epidermal Growth Factor Receptor Expression in Pemetrexed-Treated Non–Small-Cell Lung Cancer Patients

In: Clinical Lung Cancer Jg. 15 (2014) Nr. 5, S. 320 - 330.e3

ISSN: 1938-0690; 1525-7304

Online Volltext: dx.doi.org/
Holczyk, M.; Herbrik, M.; Grabellus, Florian; Podleska, Lars; Pöttgen, Christoph; Schwindenhammer, B.; Bekas, V.; Schuler, Martin; Bauer, Sebastian

Brain metastases in sarcoma patients : Incidence and outcome

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 10591

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Shaw, A.; Mehra, R.; Tan, DSW; Felip, E.; Chow, LQM; Camidge, D. R.; Vansteenkiste, J.; Sharma, S.; De Pas, T.; Riely, G. J.; Solomon, B. J.; Wolf, J.; Thomas, M.; Schuler, Martin; Liu, G.; Santoro, A.; Geraldes, M.; Sen, P.; Boral, A. J.; Yovine, A.; Kim, D. W.

Ceritinib (LDK378) for treatment of patients with ALK-rearranged (ALK plus) non small cell lung cancer (NSCLO) and brain metastases (BM) in the ascend-1 trial

In: Neuro-Oncology Jg. 16 (2014) Nr. Suppl. 5, S. v39

ISSN: 1522-8517; 1523-5866

Online Volltext: dx.doi.org/
Shaw, Alice T; Kim, Dong-Wan; Mehra, Ranee; Tan, Daniel S W; Felip, Enriqueta; Chow, Laura Q M; Camidge, D Ross; Vansteenkiste, Johan; Sharma, Sunil; De Pas, Tommaso; Riely, Gregory J; Solomon, Benjamin J; Wolf, Juergen; Thomas, Michael; Schuler, Martin; Liu, Geoffrey; Santoro, Armando; Lau, Yvonne Y; Goldwasser, Meredith; Boral, Anthony L; Engelman, Jeffrey A

Ceritinib in ALK-Rearranged Non–Small-Cell Lung Cancer

In: The New England Journal of Medicine Jg. 370 (2014) Nr. 13, S. 1189 - 1197

ISSN: 1533-4406; 0028-4793

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Tan, DSW; Shaw, A. T.; Mehra, R.; Felip, E.; Chow, LQM; Camidge, D. R.; Vansteenkiste, J. F.; Sharma, S.; De Pas, T.; Riely, G. J.; Solomon, B. J.; Wolf, J.; Thomas, M.; Schuler, Martin; Liu, G.; Santoro, A.; Geraides, M.; Boral, A.; Yovine, A. J.; Kim, D. W.

Ceritinib in Asian versus Caucasian patients (Pts) with advanced anaplastic lymphoma kinase (ALK)-rearranged (ALK plus ) NSCLC : Subgroup analysis of the ASCEND-1 trial

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 8078

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Kim, D. W.; Mehra, R.; Tan, DSW; Felip, E.; Chow, LQM; Camidge, D. R.; Vansteenkiste, J. F.; Sharma, S.; De Pas, T.; Riely, G. J.; Solomon, B. J.; Wolf, J.; Thomas, M.; Schuler, Martin; Liu, G.; Santoro, A.; Geraldes, M.; Boral, A.; Yovine, A. J.; Shaw, A. T.

Ceritinib in advanced anaplastic lymphoma kinase (ALK)-rearranged (ALK plus ) non-small cell lung cancer (NSCLC) : Results of the ASCEND-1 trial

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 8003

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schuler, Martin; Yang, C. H.; Park, K.; Bennouna, J.; Chen, Y. M.; Chouaid, C.; De Marinis, F.; Feng, J. F.; Grossi, F.; Kim, D. W.; Liu, X. Q.; Lu, S.; Strausz, J.; Vinnyk, Y.; Wiewrodt, R.; Zhou, C. C.; Chand, V. K.; Wang, B. S.; Kim, J. H.; Planchard, D.; LUX-Lung 5 Investigators

Continuation of afatinib beyond progression : Results of a randomized, open-label, phase III trial of afatanib plus paclitaxel (P) versus investigators choice chemotherapy (CT) in patients (pts) with metastatic non-small cell lung cancer (NSCLC) progressed

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 8019

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Gauler, Thomas; Espenhain, L.; Hoiczyk, M.; Nel, I.; Parr, A.; Roder, J.; Schuler, Martin; Eberhardt, Wilfried; Roder, H.; Hoffmann, Andreas-Claudius

Correlation of proteomics and first-line platinum-based chemotherapy in stage NSCLC in a large single-center cohort

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl.,

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Wu, Y. L.; Sequist, L.; Hu, C. P.; Feng, J. F.; Lu, S.; Huang, Y. C.; Li, W.; Hou, M.; Schuler, Martin; Mok, T.; Yamamoto, N.; OByrne, K.; Hirsh, V.; Gibson, N.; Massey, D.; Kim, M.; Yang, JCH

Detection of Epidermal Growth Factor Receptor (EGFR) Mutations in Circulating Cell-Free DNA in Two Phase III Studies (LUX-Lung 3 and LUX-Lung 6) of Afatinib vs Platinum-Based Chemotherapy in Patients With Advanced Non-Small Cell Lung Cancer

In: American Journal of Clinical Pathology Jg. 142 (2014) Nr. Suppl. 1, S. A182

ISSN: 0002-9173

Online Volltext: dx.doi.org/
Aktas, B.; Kasimir-Bauer, Sabine; Welt, Anja; Schuler, Martin; Kimmig, Rainer; Tewes, Mitra

Detection of disseminated tumor cells in the bone marrow and circulating tumor cells in blood of patients with early-stage male breast cancer

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. e22032

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Breitenbücher, Frank; Hoffarth, Sandra; Worm, Karl; Cortes-Incio, Diana; Gauler, Thomas; Köhler, Jens; Herold, Thomas; Kurt Werner, Schmid; Freitag, Lutz; Kasper, Stefan; Schuler, Martin

Development of a Highly Sensitive and Specific Method for Detection of Circulating Tumor Cells Harboring Somatic Mutations in Non-Small-Cell Lung Cancer Patients

In: PLoS ONE Jg. 9 (2014) Nr. 1, S. e85350

ISSN: 1932-6203

Online Volltext: dx.doi.org/ (Open Access)
Grunewald, Susanne; Mühlenberg, Thomas; Rubin, B.; Schuler, Martin; Fletcher, J. A.; Bauer, Sebastian

Effect of secondary KIT mutations on growth of GIST cells in the absence of selective pressure by imatinib in isogenic models of imatinib resistance

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 10555

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schuler, Martin; Fischer, Jürgen R.; Grohé, Christian; Gütz, Sylvia; Thomas, Michael; Kimmich, Martin; Schneider, Claus-Peter; Laack, Eckart; Märten, Angela; for the Afatinib Compassionate Use Consortium; Cortés-Incio, Diana; Gauler, Thomas

Experience With Afatinib in Patients With Non-Small Cell Lung Cancer Progressing After Clinical Benefit From Gefitinib and Erlotinib

In: The Oncologist Jg. 19 (2014) Nr. 10, S. 1100 - 1109

ISSN: 1083-7159; 2159-8401; 1549-490X

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Kohler, J.; Schuler, Martin; Kasper, Stefan; Nensa, Felix; Hense, Jörg; Forsting, Michael; Kuhl, H.

Formation of multiple pneumatoceles during anti-angiogenic treatment for metastatic colorectal cancer

In: Oncology Research and Treatment / Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg Jg. 37 (2014) Nr. Suppl. 5, S. 84 - 85

ISSN: 2296-5262
Göbel, C.; Breitenbücher, Frank; Kalkavan, H.; Hähnel, Patricia S.; Kasper, Stefan; Hoffarth, Christian; Merches, Katja; Schild, Hans-Jörg; Lang, Karl S.; Schuler, Martin

Functional expression cloning identifies COX-2 as a suppressor of antigen-specific cancer immunity

In: Cell Death and Disease Jg. 5 (2014) Nr. 12,

ISSN: 2041-4889

Online Volltext: dx.doi.org/ (Open Access)
Pogorzelski, M-; Ting, Saskia; Gauler, Thomas; Breitenbücher, Frank; Vossebein, I.; Hoffarth, S.; Markowetz, J.; Lang, S.; Bergmann, Christoph; Brandau, Sven; Abu Jawad, Jehad; Schmid, Kurt Werner; Schuler, Martin; Kasper, Stefan

Impact of human papilloma virus infection on the response of head and neck cancers to anti-epidermal growth factor receptor antibody therapy

In: Cell Death and Disease Jg. 5 (2014) Nr. 2,

ISSN: 2041-4889

Online Volltext: dx.doi.org/ (Open Access)
Köhler, Jens; Schuler, Martin

LUX-Lung 3: redundancy, toxicity or a major step forward? : Afatinib as front-line therapy for patients with metastatic EGFR-mutated lung cancer

In: Future Oncology Jg. 10 (2014) Nr. 4, S. 533 - 540

ISSN: 1744-8301; 1479-6694

Online Volltext: dx.doi.org/
Wiesweg, Marcel; Schuler, Martin

Molekulare Labordiagnostik bei gastrointestinalen Tumorerkrankungen

In: Der Gastroenterologe Jg. 9 (2014) Nr. 2, S. 127 - 137

ISSN: 1861-969X; 1861-9681

Online Volltext: dx.doi.org/
Yang, JCH; Sequist, L. V.; Schuler, Martin; Mok, T.; Yamamoto, N.; OByrne, K. J.; Hirsh, V.; Geater, S. L.; Zhou, C. C.; Massey, D.; Zazulina, V.; Wu, Y. L.

Overall survival (OS) in patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring common (Del19/L858R) epidermal growth factor receptor mutations (EGFR mut) : Pooled analysis of two large open-label phase III studies (LUX-Lung 3 [LL3] and

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 8004

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Sequist, L. V.; Cassier, P.; Varga, A.; Tabernero, J.; Schellens, J. H.; Delord, J. P.; LoRusso, P.; Camidge, D. R.; Medina, M. H.; Schuler, Martin; Campone, M.; Tian, G. G.; Wong, S.; Corral, J.; Isaacs, R.; Sen, S. K.; Porta, D. G.; Kulkarni, S. G.; Lefebvre, C.; Wolf, J.

Phase I study of BGJ398, a selective pan-FGFR inhibitor in genetically preselected advanced solid tumors

In: Cancer Research Jg. 74 (2014) Nr. 19 Suppl.,

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Van Geel, R.; Elez, E.; Bendell, J. C.; Faris, J. E.; Lolkema, MPJK; Eskens, F.; Spreafico, A.; Kavan, P.; Delord, J. P.; Schuler, Martin; Wainberg, Z. A.; Yamada, Y.; Yoshino, T.; Demuth, T.; Avsar, E.; Chatterjee, A.; Zhu, P. J.; Bernards, R.; Tabernero, J.; Schellens, JHM

Phase I study of the selective BRAFV600 inhibitor encorafenib (LGX818) combined with cetuximab and with or without the α-specific PI3K inhibitor BYL719 in patients with advanced BRAF-mutant colorectal cancer

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 3514

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Tabernero, J.; van Geel, R.; Bendell, J. C.; Spreafico, A.; Schuler, Martin; Yoshino, T.; Delord, J. P.; Yamada, Y.; Lolkema, M. P.; Fans, J. E.; Eskens, FALM; Sharma, S.; Yaeger, R.; Lenz, H. J.; Wainberg, Z.; Avsar, E.; Chatterjee, A.; Jaeger, S.; Demuth, T.; Schellens, JHM

Phase I study of the selective BRAFV600 inhibitor encorafenib (LGX818) combined with cetuximab and with or without the α-specific PI3K inhibitor alpelisib (BYL719) in patients with advanced BRAF mutant colorectal cancer

In: European Journal of Cancer Jg. 50 (2014) Nr. Suppl. 6, S. 199

ISSN: 0959-8049

Online Volltext: dx.doi.org/
Eberhardt, Wilfried; Gauler, Thomas; Pöttgen, Christoph; Friedel, G.; Veit, S.; Heinrich, V.; Welter, Stefan; Spengler, W.; Kimmich, M.; Fischer, B.; Schmidberger, H.; Gkika, E.; Cordes, S.; Hepp, R.; Luetke-Brintrup, D.; Lehmann, Nils; Schuler, Martin; Jöckel, Karl-Heinz; Stamatis, Georgios; Stuschke, Martin; ESPATUE AIO ARO Clinical Trials

Phase III study of surgery (S) versus definitive concurrent chemoradiotherapy boost (def ccCRTx-BOx) in patients (pts) with operable (OP+) stage IIIA(N2)/selected IIIb (sel IIIB) non-small cell lung cancer (NSCLC) following induction (IND) chemotherapy (CTx) and concurrent CRTx (ESPATUE)

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 7510

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Bauer, Sebastian; Hilger, Ralf A.; Mühlenberg, Thomas; Grabellus, Florian; Nagarajah, James; Hoiczyk, M.; Reichardt, A.; Ahrens, M.; Reichardt, P.; Grunewald, S.; Scheulen, Max Ernst; Pustowka, A.; Bock, E.; Schuler, Martin; Pink, D.

Phase i study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

In: British Journal of Cancer (BJC) Jg. 110 (2014) Nr. 5, S. 1155 - 1162

ISSN: 1532-1827; 0007-0920

Online Volltext: dx.doi.org/ (Open Access)
Ahnert, J. R.; Schuler, Martin; Machiels, JPH; Hess, D.; Paz-Ares, L.; Awada, A.; von Moos, R.; Steeghs, N.; Zambrano, C. C.; De Mesmaeker, P.; Richly, Heike; Herremans, C.; Joerger, M.; Jaime, J. C.; Alsina, M.; Baffert, F.; Demanse, D.; Duval, V.; Morozov, A.; Dirix, L.

Phase lb study of BEZ235 plus either paclitaxel (PTX) in advanced solid tumors (aST) or PTX plus trastuzumab (TZ) in HER2+ breast cancer (BC)

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 621

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Zambrano, C. C.; Schuler, Martin; Machiels, JPH; Hess, D.; Paz-Ares, L.; Awada, A.; von Moos, R.; Steeghs, N.; Ahnert, J. R.; De Mesmaeker, P.; Richly, Heike; Herremans, C.; Joerger, M.; Jaime, J. C.; Alsina, M.; Baffert, F.; Demanse, D.; Duval, V.; Morozov, A.; Dirix, L.

Phase lb study of buparlisib (BKM120) plus either paclitaxel (PTX) in advanced solid tumors (aST) or PTX plus trastuzumab (TZ) in HER2+ breast cancer (BC)

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 627

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Kuehnle, Marie-Christine; Attig, Sebastian; Britten, Cedrik Michael; Schulze-Bergkamen, Henning; Lordick, Florian; Von Wichert, Götz P. L .; Thuß-Patience, Peter C.; Stein, Alexander; Schuler, Martin; Bassermann, Florian; Şahin, Uǧur; Türeci, Özlem

Phenotyping of peripheral blood mononuclear cells of patients with advanced heavily pre-treated adenocarcinoma of the stomach and gastro-esophageal junction

In: Cancer Immunology, Immunotherapy Jg. 63 (2014) Nr. 12, S. 1273 - 1284

ISSN: 0340-7004

Online Volltext: dx.doi.org/
Schmidt, Lars Henning; Görlich, Dennis; Spieker, Tillmann; Rohde, Christian; Schuler, Martin; Mohr, Michael; Humberg, Julia; Sauer, Tim; Thoenissen, Nils; Huge, Andreas; Voss, Reinhard; Marra, Alessandro; Faldum, Andreas; Müller-Tidow, Carsten; Berdel, Wofgang E.; Wiewrodt, Rainer

Prognostic impact of Bcl-2 depends on tumor histology and expression of MALAT-1 lncRNA in non-small-cell lung cancer

In: Journal of Thoracic Oncology Jg. 9 (2014) Nr. 9, S. 1294 - 1304

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Kordelas, L.; Bauer, Sebastian; Schuler, Martin; Beelen, Dietrich; Gauler, Thomas

Successful resuscitation of a patient with ventricular fibrillation due to hypomagnesemia under cetuximab therapy

In: TumorDiagnostik & Therapie Jg. 35 (2014) Nr. 1, S. 25 - 27

ISSN: 1439-1279; 0722-219X

Online Volltext: dx.doi.org/
Kasper, Stefan; Schuler, Martin

Targeted therapies in gastroesophageal cancer

In: European Journal of Cancer Jg. 50 (2014) Nr. 7, S. 1247 - 1258

ISSN: 1879-0852; 0959-8049

Online Volltext: dx.doi.org/
Nogova, L.; Sequist, L. V.; Cassier, P. A.; Hidalgo, M.; Delord, J. P.; Schuler, Martin; Lim, W. T.; Camidge, D. R.; Buettner, R.; Heukamp, L. C.; Gardizi, M.; Scheffler, M.; Kambartel, K.; Ringeisen, F. P.; Sen, S.; Isaacs, R.; Joannaert, M.; Lefebvre, C.; Wolf, J.

Targeting FGFR1-amplified lung squamous cell carcinoma with the selective pan-FGFR inhibitor BGJ398

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. 8034

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Mühlenberg, T.; Grunewald, S.; Schuler, Martin; Bauer, Sebastian

Targeting glucose metabolism by 2-deoxyglucose in gastrointestinal stromal tumors

In: Cancer Research Jg. 74 (2014) Nr. 19 Suppl.,

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Pastille, Eva; Bardini, Katrin; Fleissner, Diana; Adamczyk, Alexandra; Frede, Annika; Wadwa, Munisch; Smolinski, Dorthe von; Kasper, Stefan; Sparwasser, Tim; Gruber, Achim D.; Schuler, Martin; Sakaguchi, Shimon; Roers, Axel; Müller, Werner; Hansen, Wiebke; Buer, Jan; Westendorf, Astrid

Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer

In: Cancer Research Jg. 74 (2014) Nr. 16, S. 4258 - 4269

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Köhler, J.; Schuler, Martin

Afatinib, Erlotinib and Gefitinib in the First-Line Therapy of EGFR Mutation-Positive Lung Adenocarcinoma : A Review

In: Oncology Research and Treatment Jg. 36 (2013) Nr. 9, S. 510 - 518

ISSN: 0378-584X; 1423-0240

Online Volltext: dx.doi.org/
Kasper, Stefan; Meiler, Johannes; Knipp, Heike; Hoehler, T.; Reimer, P.; Steinmetz, T.; Berger, W.; Linden, G.; Ting, Saskia; Markus, P.; Paul, Andreas; Schuler, Martin; Trarbach, Tanja

Cetuximab biweekly plus mFOLFOX6 as first-line therapy in patients (pts) with KRAS wild-type (wt) metastatic colorectal cancer (mCRC) : An interim analysis of the CEBIFOX trial

In: Journal of Clinical Oncology (JCO) Jg. 31 (2013) Nr. 15 Suppl., S. e14502

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Chen, Xiaofeng; Zhu, Quan; Zhu, Lingjun; Pei, Dong; Liu, Yiqian; Yin, Yongmei; Schuler, Martin; Shu, Yongqian

Clinical perspective of afatinib in non-small cell lung cancer

In: Lung Cancer Jg. 81 (2013) Nr. 2, S. 155 - 161

ISSN: 0169-5002

Online Volltext: dx.doi.org/
Juntermanns, Benjamin; Sotiropoulos, Georgios; Radunz, Sonia; Reis, Henning; Heuer, Matthias; Baba, Hideo Andreas; Canbay, Aliekber; Schuler, Martin; Gerken, Guido; Paul, Andreas; Kaiser, Gernot Maximil

Comparison of the Sixth and the Seventh Editions of the UICC Classification for Perihilar Cholangiocarcinoma

In: Annals of Surgical Oncology Jg. 20 (2013) Nr. 1, S. 277 - 284

ISSN: 1068-9265; 1534-4681

Online Volltext: dx.doi.org/
Heusch, Philipp; Buchbender, Christian; Köhler, Jens; Nensa, Felix; Beiderwellen, Karsten; Kühl, Hilmar; Lanzman, Rotem S.; Wittsack, Hans-Jörg; Gomez, Benedikt; Gauler, Thomas; Schuler, Martin; Forsting, Michael; Bockisch, Andreas; Antoch, Gerald; Heusner, Till Alexander

Correlation of the apparent diffusion coefficient (ADC) with the standardized uptake value (SUV) in hybrid 18F-FDG PET/MRI in non-small cell lung cancer (NSCLC) lesions : Initial results

In: RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren Jg. 185 (2013) Nr. 11, S. 1056 - 1062

ISSN: 0340-1618; 1438-9010; 1438-9029

Online Volltext: dx.doi.org/
Simon, Susanne; Grabellus, Florian; Ferrera, Loretta; Galietta, Luis; Schwindenhammer, Benjamin; Mühlenberg, Thomas; Täger, Georg; Eilers, Grant; Treckmann, Jürgen-Walter; Breitenbücher, Frank; Schuler, Martin; Taguchi, Takahiro; Fletcher, Jonathan A.; Bauer, Sebastian

DOG1 Regulates Growth and IGFBP5 in Gastrointestinal Stromal Tumors

In: Cancer Research Jg. 73 (2013) Nr. 12, S. 3661 - 3670

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Yang, JCH; Sequist, L.; OByrne, K.; Schuler, Martin; Mok, T.; Geater, S.; Massey, D.; OBrien, D.; Zazulina, V.; Wu, Y. L.

Epidermal growth factor receptor (EGFR)-mediated adverse events (AEs) in patients (pts) with EGFR mutation positive (EGFR M plus ) non-small cell lung cancer treated with afatinib

In: European Journal of Cancer Jg. 49 (2013) Nr. Suppl. 2, S. 190

ISSN: 0959-8049

Online Volltext: dx.doi.org/
Wiesweg, Marcel; Ting, Saskia; Reis, Henning; Worm, Karl; Kasper, Stefan; Tewes, Mitra; Welt, Anja; Richly, Heike; Meiler, Johannes; Bauer, Sebastian; Hense, Jörg; Gauler, Thomas; Köhler, Jens; Eberhardt, Wilfried; Darwiche, Kaid; Freitag, Lutz; Stamatis, Georgios; Breitenbücher, Frank; Wohlschläger, Jeremias; Theegarten, Dirk; Derks, Cordula; Cortes-Incio, Diana; Linden, Gabriele; Skottky, Silke; Lütkes, Peter; Dechene, Alexander; Paul, Andreas; Markus, Peter; Schmid, Kurt Werner; Schuler, Martin

Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center

In: European Journal of Cancer Jg. 49 (2013) Nr. 15, S. 3076 - 3082

ISSN: 0959-8049; 1879-0852

Online Volltext: dx.doi.org/
Nel, I.; Gauler, Thomas; Eberhardt, Wilfried; Nickel, A. C.; Schuler, Martin; Thomale, Jürgen; Hoffmann, Andreas-Claudius

Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumour cells and response to platinum treatment

In: British Journal of Cancer (BJC) Jg. 109 (2013) Nr. 5, S. 1223 - 1229

ISSN: 1532-1827; 0007-0920

Online Volltext: dx.doi.org/ (Open Access)
Rebmann, Vera; Gauler, Thomas; Schott, B.; Schott, P.; Bauer, Sebastian; Opalka, Bertram; Stamatis, Georgios; Eberhardt, Wilfried; Schuler, Martin; Horn, Peter

Free soluble HLA-G molecules but not exosome-derived soluble HLA-G molecules are of prognostic relevance in lung cancer patients

In: Tissue Antigens Jg. 81 (2013) Nr. 5, S. 282 - 283

ISSN: 0001-2815; 1399-0039

Online Volltext: dx.doi.org/
Falkenhorst, J.; Mühlenberg, Thomas; Grunewald, S.; Marino-Enriquez, A.; Schuler, Martin; Fletcher, J.; Bauer, Sebastian;

IAP gene alterations and therapeutic modulation of IAPs by Smac mimetics in GIST
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,

In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 245 - 246

ISSN: 0378-584X; 1423-0240
OByrne, K. J.; Sequist, L. V.; Schuler, Martin; Yamamoto, N.; Hirsh, V.; Mok, T.; Lungershausen, J.; Shahidi, M.; Palmer, M.; Yang, JCH

LUX-Lung 3 : Symptom and health-related quality of life results from a randomized phase III study in 1st-line advanced NSCLC patients harbouring EGFR mutations

In: Lung Cancer Jg. 79 (2013) Nr. Suppl. 1, S. 11

ISSN: 0169-5002

Online Volltext: dx.doi.org/
Kasper, Stefan; Breitenbücher, Frank; Reis, Henning; Brandau, Sven; Worm, K.; Köhler, J.; Paul, Andreas; Trarbach, Tanja; Schmid, Kurt Werner; Schuler, Martin

Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockade

In: Oncogene Jg. 32 (2013) Nr. 23, S. 2873 - 2881

ISSN: 0950-9232; 1476-5594

Online Volltext: dx.doi.org/
Sequist, Lecia V.; Yang, James Chih-Hsin; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Hirsh, Vera; Mok, Tony; Geater, Sarayut Lucien; Orlov, Sergey; Tsai, Chun-Ming; Boyer, Michael; Su, Wu-Chou; Bennouna, Jaafar; Kato, Terufumi; Gorbunova, Vera; Lee, Ki Hyeong; Shah, Riyaz; Massey, Dan; Zazulina, Victoria; Shahidi, Mehdi; Schuler, Martin

Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations

In: Journal of Clinical Oncology (JCO) Jg. 31 (2013) Nr. 27, S. 3327 - 3334

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Nell, I.; Gauler, Thomas; Nickel, A. C.; Alotaibi, S.; Thomale, Jürgen; Schuler, Martin; Hoffmann, Andreas-Claudius

Pre-therapeutic ex-vivo repair kinetics of cisplatin-DNA-adducts in circulating tumor cells (CTC) as platinum resistance test

In: Lung Cancer Jg. 79 (2013) Nr. Suppl. 1, S. 2

ISSN: 0169-5002

Online Volltext: dx.doi.org/
Welt, Anja; Tewes, Mitra; Aktas, Bahriye; Hoffmann, Oliver; Wiesweg, Marcel; Ting, Saskia; Reis, Henning; Worm, Karl; Richly, Heike; Hense, Jörg; Palmer, Michael R.; Lee, Benjamin H.; Wendling, Johanna; Kossow, Josef; Scheulen, Max Ernst; Lehnerdt, Cathrin; Kohl, Marzena; Derks, Cordula; Skottky, Silke; Haus, Ulrike; Schmid, Kurt Werner; Kimmig, Rainer; Schuler, Martin; Kasper, Stefan

Preemptive tumor profiling for biomarker-stratified early clinical drug development in metastatic breast cancer patients

In: Breast Cancer Research and Treatment Jg. 142 (2013) Nr. 1, S. 81 - 88

ISSN: 1573-7217; 0167-6806

Online Volltext: dx.doi.org/
Juric, D.; Gonzalez-Angulo, A. M.; Burris, H. A.; Schuler, Martin; Schellens, J.; Berlin, J.; Gupta, A.; Seggewiss-Bernhardt, R.; Adamo, B.; Gil-Martin, M.; Bootle, D.; Boehm, M.; De Buck, S.; Demanse, D.; Quadt, C.; Baselga, J.

Preliminary safety, pharmacokinetics and anti-tumor activity of BYL719, an alpha-specific P13K inhibitor in combination with fulvestrant : Results from a phase I study

In: Cancer Research Jg. 73 (2013) Nr. Suppl. 24,

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Gonzalez-Angulo, A. M.; Juric, D.; Argiles, G.; Schellens, JHM; Burris, H. A.; Berlin, J.; Middleton, M. R.; Schuler, Martin; Van Geel, R.; Helgason, T.; Bootle, D.; Boehm, M.; Goggin, T. K.; Demanse, D.; Quadt, C.; Baselga, J.

Safety, pharmacokinetics, and preliminary activity of the α-specific PI3K inhibitor BYL719 : Results from the first-in-human study

In: Journal of Clinical Oncology (JCO) Jg. 31 (2013) Nr. 15 Suppl., S. 2531

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schuler, Martin; Zvirbule, Z.; Lordick, F.; Krilova, A.; Helbig, U.; Schulze-Bergkamen, H.; Thuss-Patience, P. C.; von Wichert, G.; Schulmann, K.; Trarbach, Tanja; Bauer, Sebastian; Mueller, C.; Al-Batran, S. E.; Huber, C.; Sahin, U.; Tureci, O.

Safety, tolerability, and efficacy of the first-in-class antibody IMAB362 targeting claudin 18.2 in patients with metastatic gastroesophageal adenocarcinomas

In: Journal of Clinical Oncology (JCO) Jg. 31 (2013) Nr. 15 Suppl., S. 4080

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Grunewald, S.; Mühlenberg, Thomas; Ketzer, J.; Backs, M.; Rubin, B.; Schuler, Martin; Fletcher, J.; Bauer, Sebastian;

Secondary KIT mutations negatively impact cell growth in a novel isogenic model of imatinib-resistance in GIST
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,

In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 178 - 179

ISSN: 0378-584X; 1423-0240
Christoph, Daniel; Reyna-Asuncion, Bernadette; Hassan, Biftu; Tran, Cindy; Maltzman, Julia D.; O'Shannessy, Daniel J.; Wynes, Murry W.; Gauler, Thomas; Wohlschläger, Jeremias; Hoiczyk, M.; Schuler, Martin; Eberhardt, Wilfried; Hirsch, Fred R.

Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexed

In: Journal of Thoracic Oncology Jg. 8 (2013) Nr. 1, S. 19 - 30

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Molzan, M.; Kasper, Stefan; Röglin, L.; Skwarczynska, M.; Sassa, T.; Inoue, T.; Breitenbücher, Frank; Ohkanda, J.; Kato, N.; Schuler, Martin; Ottmann, C.

Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers

In: ACS Chemical Biology Jg. 8 (2013) Nr. 9, S. 1869 - 1875

ISSN: 1554-8937; 1554-8929

Online Volltext: dx.doi.org/
Yang, James Chih-Hsin; Hirsh, Vera; Schuler, Martin; Yamamoto, Nobuyuki; O'Byrne, Kenneth J.; Mok, Tony S.K.; Zazulina, Victoria; Shahidi, Mehdi; Lungershausen, Juliane; Massey, Dan; Palmer, Michael; Sequist, Lecia V.

Symptom control and quality of life in lux-lung 3 : A phase III study of afatinib or cisplatin/pemetrexed in patients with advanced lung adenocarcinoma with EGFR mutations

In: Journal of Clinical Oncology (JCO) Jg. 31 (2013) Nr. 27, S. 3342 - 3350

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Hoiczyk, Mathias; Grabellus, Florian; Podleska, Lars; Ahrens, Marit; Schwindenhammer, Benjamin; Täger, Georg; Pöttgen, Christoph; Schuler, Martin; Bauer, Sebastian

Trabectedin in metastatic soft tissue sarcomas : Role of pretreatment and age

In: International Journal of Oncology Jg. 43 (2013) Nr. 1, S. 23 - 28

ISSN: 1791-2423; 1791-2423

Online Volltext: dx.doi.org/
Schmidt, L. H.; Spieker, T.; Schuler, Martin; Marra, A.; Wiebe, K.; Berdel, W.; Mueller-Tidow, C.; Rainer, W.

Tumor laterality influences the prognostic impact of Bcl-2 expression in curatively resected NSCLC patients

In: European Respiratory Journal (ERJ) Jg. 42 (2013) Nr. Suppl. 57,

ISSN: 0903-1936; 1399-3003

Online Volltext
Schuler, Martin

Ärztliche Behandlung von an Krebs Erkrankten : Alles ganz anders?

In: Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen Jg. 107 (2013) Nr. 2, S. 116 - 119

ISSN: 1865-9217; 2212-0289

Online Volltext: dx.doi.org/
Schuler, Martin; Awada, Ahmad; Harter, Philipp; Canon, Jean Luc; Possinger, Kurt; Schmidt, Marcus; De Grève, Jacques; Neven, Patrick; Dirix, Luc; Jonat, Walter; Beckmann, Matthias W.; Schütte, Jochen; Fasching, Peter A.; Gottschalk, Nina; Besse-Hammer, Tatiana; Fleischer, Frank; Wind, Sven; Uttenreuther-Fischer, Martina; Piccart, Martine; Harbeck, Nadia

A phase II trial to assess efficacy and safety of afatinib in extensively pretreated patients with HER2-negative metastatic breast cancer

In: Breast Cancer Research and Treatment Jg. 134 (2012) Nr. 3, S. 1149 - 1159

ISSN: 1573-7217; 0167-6806

Online Volltext: dx.doi.org/ (Open Access)
Yang, J. C.; Schuler, Martin; Yamamoto, N.; OByrne, K. J.; Hirsh, V.; Mok, TSK; Massey, D.; Zazulina, V.; Shahidi, M.; Sequist, L. V.

Activity of afatinib in uncommon epidermal growth factor receptor (EGFR) mutations in Lux-Lung 3, a phase III trial of afatinib or cisplatin/pemetrexed EGFR mutation-positive lung cancer

In: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 9, S. 410 - 411

ISSN: 0923-7534; 1569-8041
Kim, J. H.; Grossi, F.; De Marinis, F.; Cobo, M.; Yang, JCH; Ragulin, Y.; Bondarenko, I. N.; Chand, V. K.; Wang, B. S.; Gracien, E.; Schuler, Martin

Afatinib monotherapy in patients with metastatic squamous cell carcinoma of the lung progressing after erlotinib/gefitinib (E/G) and chemotherapy : Interim subset analysis from a phase III trial

In: Journal of Clinical Oncology Jg. 30 (2012) Nr. Suppl. 15,

ISSN: 0732-183X; 1527-7755
Scheulen, Max Ernst; Richly, Heike; Kalkavan, H.; Hoffmann, Andreas-Claudius; Virchow, I.; Hilger, Ralf A.; Koeppen, Susanne; Sure, Ulrich; Schuler, Martin; Hense, Jörg

An investigator-initiated monocentric phase I dose escalation trial of temsirolimus and irinotecan (TEMIR) in patients with relapsing glioblastoma multiforme (reGBM)

In: Journal of Clinical Oncology Jg. 30 (2012) Nr. Suppl. 15, S. 2086

ISSN: 0732-183X; 1527-7755
Kasper, Stefan; Meiler, Johannes; Schuler, Martin

Antikörper zur adoptiven Immuntherapie solider Tumoren

In: Der Onkologe Jg. 18 (2012) Nr. 9, S. 757 - 769

ISSN: 1433-0415; 0947-8965

Online Volltext: dx.doi.org/
Olschlager, K.; Grabellus, Florian; Schnell, R.; Geffken, M.; Hoiczyk, M.; Ahrens, M.; Podleska, Lars; Tager, G.; Treckmann, Jürgen-Walter; Pöttgen, Christoph; Schuler, Martin; Bauer, Sebastian

Chemotherapy in resectable sarcomas with complex karyotypes - a single center retrospective analysis

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 150 - 150

ISSN: 0378-584X; 1423-0240
Christoph, Daniel; Hoffmann, Andreas-Claudius; Gauler, Thomas; Asuncion, Bernadette Reyna; Loewendick, Heike; Peglow, Anja; Hassan, Biftu; Tran, Cindy; Wynes, Murry W.; Schuler, Martin; Eberhardt, Wilfried; Hirsch, Fred R.

Detection of circulating lung cancer cells with strong thymidylate synthase reactivity in the peripheral blood of a patient with pulmonary adenocarcinoma treated with pemetrexed

In: Journal of Thoracic Oncology Jg. 7 (2012) Nr. 4, S. 766 - 767

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Wolf, J.; Nogova, L.; Heukamp, L. C.; Bos, M.; Schuler, Martin; Sequist, L.; Tian, G. G.; Ringeisen, F.; Buettner, R.; Thomas, R.

Developments in targeted therapy : FGFR1 inhibition in lung cancer

In: Journal of Thoracic Oncology Jg. 7 (2012) Nr. Suppl. 6, S. 23

ISSN: 1556-0864; 1556-1380
Drescher, O.; Eberhardt, Wilfried; Prittwitz, R.; Gkika, E.; Korfee, Sönke; Theegarten, Dirk; Welter, Stefan; Krbek, T.; Stamatis, Georgios; Pöttgen, Christoph; Schuler, Martin; Christoph, Daniel

Distribution pattern of metastases and their associations with survival of malignant pleural mesothelioma patients undergoing different treatment modalities

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 140

ISSN: 0378-584X; 1423-0240
Nogova, L.; Gardizi, M.; Bos, MCA; Bitter, E.; Schildhaus, Hans-Ulrich; Heukamp, L. C.; Topelt, K.; Zander, T.; Scheffler, M.; Mattonet, C.; Gokkurt, E.; Risse, F.; Schuler, Martin; Sequist, L.; Tian, G. G.; Ringeisen, F.; Thomas, R.; Buttner, R.; Wolf, J.

Early clinical evaluation of FGFR1 inhibition in lung cancer : Preliminary results of a phase I study in FGFR1 amplified lung cancer patients treated with BGJ398, a pan FGFR inhibitor

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 137

ISSN: 0378-584X; 1423-0240
Christoph, Daniel; Asuncion, Bernadette Reyna; Mascaux, Celine; Tran, Cindy; Lu, Xian; Wynes, Murry W.; Gauler, Thomas; Wohlschläger, Jeremias; Theegarten, Dirk; Neumann, Volker; Hepp, Rodrigo; Welter, Stefan; Stamatis, Georgios; Tannapfel, Andrea; Schuler, Martin; Eberhardt, Wilfried; Hirsch, Fred R.

Folylpoly-Glutamate Synthetase Expression Is Associated with Tumor Response and Outcome from Pemetrexed-Based Chemotherapy in Malignant Pleural Mesothelioma

In: Journal of Thoracic Oncology Jg. 7 (2012) Nr. 9, S. 1440 - 1448

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Welter, Stefan; Grabellus, Florian; Bauer, Sebastian; Schuler, Martin; Eberhardt, Wilfried; Tötsch, M.; Stamatis, Georgios

Growth patterns of lung metastases from sarcoma : prognostic and surgical implications from histology

In: Interactive Cardiovascular and Thoracic Surgery Jg. 15 (2012) Nr. 4, S. 612 - 617

ISSN: 1569-9285; 1569-9293

Online Volltext: dx.doi.org/
Kohler, J.; Worm, K.; Gauler, Thomas; Hoiczyk, M.; Theegarten, Dirk; Eberhardt, Wilfried; Hense, Jörg; Breitenbücher, Frank; Schmid, Kurt Werner; Schuler, Martin

Impact of EGFR mutation status on clinical benefit from BIBW 2992 in patients (PTS) with advanced non-small lung cancer (NSCLC) progressing after chemotherapy (CTX) and erlotinib (E) or gefitinib (G) - a single center experience

In: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 9, S. 437 - 438

ISSN: 0923-7534; 1569-8041
Pogorzelski, M.; Ting, Saskia; Gauler, Thomas; Vossebein, I.; Breitenbucher, F.; Lang, Stephan; Hoffmann, T. K.; Bergmann, Christoph; Schmid, Kurt Werner; Schuler, Martin; Kasper, Stefan

Impact of HPV status on the response of head and neck cancers to the anti-EGFR antibody cetuximab

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 193 - 193

ISSN: 0378-584X; 1423-0240
Meiler, Johannes; Guyot, M.; Hoffarth, S.; Wesarg, E.; Höhn, Y.; Breitenbücher, Frank; Schuler, Martin

Individual dose and scheduling determine the efficacy of combining cytotoxic anticancer agents with a kinase inhibitor in non-small-cell lung cancer

In: Journal of Cancer Research and Clinical Oncology Jg. 138 (2012) Nr. 8, S. 1385 - 1394

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/
Falkenhorst, J.; Mühlenberg, Thomas; Simon, S.; Grabellus, Florian; Breitenbucher, F.; Schuler, Martin; Fletcher, J. A.; Bauer, Sebastian

Inhibitors of Apoptosis Proteins (IAPs) in gastrointestinal stromal tumors - a therapeutic target?

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 249

ISSN: 0378-584X; 1423-0240
Schuler, Martin; Planchard, D.; Yang, JCH; Kim, J. H.; De Marinis, F.; Chen, Y. M.; Zhou, C. C.; Bennouna, J.; Liu, X. Q.; Feng, J. F.; Bidoli, P.; Strausz, J.; Ou, SHI; Chand, V. K.; Wang, B. S.; Munzert, G. M.; Park, K.

Interim analysis of afatinib monotherapy in patients with metastatic NSCLC progressing after chemotherapy and erlotinib/gefitinib (E/G) in a trial of afatinib plus paclitaxel versus investigator's choice chemotherapy following progression on afatinib mono

In: Journal of Clinical Oncology Jg. 30 (2012) Nr. Suppl. 15, S. 7557

ISSN: 0732-183X; 1527-7755
Schuler, Martin; Planchard, D.; Yang, JCH; Kim, J. H.; De Marinis, F.; Chen, Y. M.; Zhou, C. C.; Bennouna, J.; Liu, X. Q.; Feng, J. F.; Bidoli, P.; Strausz, J.; Ou, SHI; Chand, V. K.; Wang, B. S.; Munzert, G. M.; Park, K.

Interim analysis of afatinib monotherapy in patients with metastatic NSCLC progressing after chemotherapy and erlotinib/gefitinib (E/G) in a trial of afatinib plus paclitaxel versus investigators choice chemotherapy following progression on afatinib monot

In: Journal of Clinical Oncology Jg. 30 (2012) Nr. Suppl. 15,

ISSN: 0732-183X; 1527-7755
Hoiczyk, Mathias; Iliodromitis, Konstantinos; Bauer, Sebastian; Konorza, Thomas; Philipp, Sebastian; Bankfalvi, Agnes; Gerl, Jan Mikael; Schuler, Martin; Erbel, Raimund

Intimal sarcoma of the pulmonary artery with unusual findings : a case report

In: Clinical Research in Cardiology Jg. 101 (2012) Nr. 5, S. 397 - 401

ISSN: 1861-0692; 1861-0684

Online Volltext: dx.doi.org/
Christoph, Daniel; Asuncion, B. R.; Hassan, B.; Maltzman, J.; O'Shannessy, D.; Gauler, Thomas; Wynes, M. W.; Schuler, Martin; Eberhardt, Wilfried; Hirsch, F. R.

Investigation of Folate Receptor alpha and Thymidylate Synthase Proteins Expression in metastatic Non-Small Cell Lung Cancer Patients treated with Pemetrexed-based Chemotherapy

In: Journal of Thoracic Oncology Jg. 7 (2012) Nr. 9, Suppl. 4, S. S211 - S212

ISSN: 1556-0864; 1556-1380
Sequist, L. V.; Schuler, Martin; Yamamoto, N.; OByrne, K. J.; Hirsh, V.; Mok, TSK; Lungershausen, J.; Shahidi, M.; Palmer, M.; Yang, J. C.

LUX-Lung 3 : Symptom and health-related quality of life results from a randomized phase III study in 1st-line advanced NSCLC patients harbouring EGFR mutations

In: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 9, S. 402

ISSN: 0923-7534; 1569-8041
Sequist, L.; Schuler, Martin; Yamamoto, N.; OByrne, K.; Hirsh, V.; Mok, T.; Massey, D.; Zazulina, V.; Shahidi, M.; Yang, J.

LUX-Lung 3 : A Randomized, Open-Label, Phase III Study of Afatinib vs Pemetrexed and Cisplatin as First-Line Treatment for Patients with Advanced Adenocarcinoma of the Lung Harboring EGFR-Activating Mutations (Subgroup Analysis)

In: Journal of Thoracic Oncology Jg. 7 (2012) Nr. 9, Suppl. 4, S. 203

ISSN: 1556-0864; 1556-1380
Yang, JCH; Schuler, Martin; Yamamoto, N.; OByrne, K. J.; Hirsh, V.; Mok, T.; Geater, S. L.; Orlov, S. V.; Tsai, C. M.; Boyer, M. J.; Su, W. C.; Bennouna, J.; Kato, T.; Gorbunova, V.; Lee, K. H.; Shah, RNH; Massey, D.; Lorence, R. M.; Shahidi, M.; Sequist, L. V.

LUX-Lung 3 : A randomized, open-label, phase III study of afatinib versus pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harboring EGFR-activating mutations

In: Journal of Clinical Oncology Jg. 30 (2012) Nr. Suppl. 15, S. LBA7500

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Boyer, M.; Schuler, Martin; Yamamoto, N.; OByrne, K.; Hirsh, V.; Mok, T.; Massey, D.; Zazulina, V.; Shahidi, M.; Sequist, L.; Yang, J. C.

Lux-Lung 3 : a randomized, open-label, phase III study of afatinib versus pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harbouring EGFR-activating mutations

In: Journal of Thoracic Oncology Jg. 7 (2012) Nr. 9, Suppl. 3, S. 161

ISSN: 1556-0864; 1556-1380
OByrne, K.; Schuler, Martin; Yamamoto, N.; Hirsh, V.; Mok, T.; Massey, D.; Zazulina, V.; Shahidi, M.; Sequist, L.; Yang, J.

Lux-Lung 3 : A randomized, open-label, phase III study of afatinib vs. pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harboring EGFR activating mutations

In: Journal of Thoracic Oncology Jg. 7 (2012) Nr. 7, S. 102

ISSN: 1556-0864; 1556-1380
Yamamoto, N.; Schuler, Martin; OByrne, K.; Hirsh, V.; Mok, T.; Kato, T.; Yoshioka, H.; Okamoto, I.; Yokoyama, A.; Massey, D.; Jones, H.; Zazulina, V.; Shahidi, M.; Sequist, L.; Yang, JCH

Lux-LungG 3 : Afatinib versus cisplatin and pemetrexed in Japanese patients with adenocarcinoma of the lung harboring an EGFR mutation

In: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 11, S. 8

ISSN: 0923-7534; 1569-8041
Köhler, Johannes; Schuler, Martin

Molekular zielgerichtete Tumortherapien : aktueller Stand und künftige Entwicklungen

In: TumorDiagnostik & Therapie Jg. 33 (2012) Nr. 6, S. 311 - 314

ISSN: 1439-1279

Online Volltext: dx.doi.org/
Henze, Joern; Mühlenberg, Thomas; Simon, Susanne; Grabellus, Florian; Rubin, Brian; Täger, Georg; Schuler, Martin; Treckmann, Jürgen-Walter; Debiec-Rychter, Maria; Taguchi, Takahiro; Fletcher, Jonathan A.; Bauer, Sebastian

P53 modulation as a therapeutic strategy in gastrointestinal stromal tumors

In: PLoS ONE Jg. 7 (2012) Nr. 5,

ISSN: 1932-6203

Online Volltext: dx.doi.org/ (Open Access)
Markova, Boyka; Hähnel, Patricia S.; Kasper, Stefan; Herbertz, Stephan; Schuler, Martin; Breitenbücher, Frank

Pharmacologic inhibition of mTOR antagonizes the cytotoxic activity of pemetrexed in non-small cell lung cancer

In: Journal of Cancer Research and Clinical Oncology Jg. 138 (2012) Nr. 4, S. 545 - 554

ISSN: 1432-1335; 0171-5216; 0084-5353; 0301-1585

Online Volltext: dx.doi.org/
Ahnert, J. R.; Burris, H. A.; Schellens, JHM; Schuler, Martin; Goodman, O.; Britten, C.; Richards, D.; Demanse, D.; Silva, A.; Baselga, J.

Phase I Dose-escalation Study of the Oral Dual MTOR/PI3K Inhibitor BEZ235, Solid Dispersion System (SDS) Sachet Formulation, in Patients with Advanced Solid Tumors

In: European Journal of Cancer Jg. 48 (2012) Nr. Suppl. 6, S. 112

ISSN: 0959-8049

Online Volltext: dx.doi.org/
Bauer, Sebastian; Hilger, Ralf A.; Grabellus, Florian; Nagarajah, James; Hoiczyk, M.; Reichardt, A.; Ahrens, M.; Pink, D.; Mühlenberg, Thomas; Scheulen, Max Ernst; Schuler, Martin; Reichardt, P.

Phase I trial of panobinostat (P) and imatinib (IM) in patients with treatment-refractory gastrointestinal stromal tumors (GIST)

In: Journal of Clinical Oncology Jg. 30 (2012) Nr. Suppl. 15, S. 10032

ISSN: 0732-183X; 1527-7755
Dirix, L.; Schuler, Martin; Machiels, J.; Hess, D.; Awada, A.; Steeghs, N.; Paz-Ares, L.; von Moos, R.; Rabault, B.; Rodon, J.

Phase IB dose-escalation study of BEZ235 or BKM 120 in combination with paclitaxel (PTX) in patients with advanced solid tumors

In: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 9, S. 157 - 158

ISSN: 0923-7534; 1569-8041
Schmidt, Markus; Rüttinger, Dominik; Sebastian, M.; Hanusch, Claus A.; Marschner, Norbert; Bäuerle, Patrick A.; Wolf, Andreas; Göppel, Gertrud; Oruzio, Daniel; Schlimok, Günter; Steger, Günther G.; Wolf, Christopher; Eiermann, Wolfgang; Lang, Alois; Schuler, Martin

Phase IB study of the EpCAM antibody adecatumumab combined with docetaxel in patients with epcampositive relapsed or refractory advanced-stage breast cancer

In: Annals of Oncology Jg. 23 (2012) Nr. 9, S. 2306 - 2313

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/ (Open Access)
Hoiczyk, M.; Kuschel, P.; Grabellus, Florian; Geffken, M.; Ahrens, M.; Schuler, Martin; Bauer, Sebastian

Rechallenge with ifosfamide-containing regimen as salvage option for patients with metastatic soft tissue sarcomas progressing after multiple pretreatments

In: Journal of Clinical Oncology Jg. 30 (2012) Nr. Suppl. 15,

ISSN: 0732-183X; 1527-7755
Christoph, Daniel; Asuncion, B. R.; Hassan, B.; Maltzman, J.; O'Shannessy, D.; Gauler, Thomas; Wohlschläger, Jeremias; Wynes, M. W.; Schuler, Martin; Eberhardt, Wilfried; Hirsch, F. R.

Significance of Folate Receptor alpha (FRA) and Thymidylate Synthase (TS) expression in metastatic non-small cell lung cancer patients treated with pemetrexed-based chemotherapy

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 34

ISSN: 0378-584X; 1423-0240
Kasper, Stefan; Breitenbücher, Frank; Heidel, F.; Hoffarth, S.; Markova, B.; Schuler, Martin; Fischer, T.

Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies

In: Blood Cancer Journal Jg. 2 (2012) Nr. 3, S. e60

ISSN: 2044-5385

Online Volltext: dx.doi.org/ (Open Access)
Kasper, Stefan; Reis, Henning; Breitenbücher, Frank; Markowetz, J.; Pogorzelski, M.; Trarbach, Tanja; Worm, K.; Schmid, Kurt Werner; Schuler, Martin

Targeting the anti-apoptotic protein BCL-XL to overcome RAS mediated resistance to anti-EGFR antibody therapy in colorectal cancer

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 253

ISSN: 0378-584X; 1423-0240
Welt, Anja; Kossow, J.; Tewes, Mitra; Seeber, S.; Schuler, Martin

Trends in survival of patients with metastatic breast cancer

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 187

ISSN: 0378-584X; 1423-0240
Wiesweg, Marcel; Kasper, Stefan; Wohlschläger, Jeremias; Ting, Saskia; Skottky, S.; Worm, K.; Derks, C.; Tewes, Mitra; Breitenbücher, Frank; Gauler, Thomas; Eberhardt, Wilfried; Ahrens, M.; Hoiczyk, M.; Meiler, Johannes; Hense, Jörg; Welt, Anja; Theegarten, Dirk; Freitag, Lutz; Kimmig, Rainer; Schmid, Kurt Werner; Schuler, Martin

VVTZ-Tumorprofil - First results of a preemptive biomarker profiling program in relation to personalized clinical drug development at a large German Comprehensive Cancer Center

In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 204 - 204

ISSN: 0378-584X; 1423-0240
Christoph, Daniel; Kasper, Stefan; Gauler, Thomas; Loesch, Christian; Engelhard, Marianne; Theegarten, Dirk; Pöttgen, Christoph; Hepp, Rodrigo; Peglow, Anja; Loewendick, Heike; Welter, Stefan; Stamatis, Georgios; Hirsch, Fred R.; Schuler, Martin; Eberhardt, Wilfried; Wohlschläger, Jeremias

Βv-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancer

In: British Journal of Cancer (BJC) Jg. 107 (2012) Nr. 5, S. 823 - 830

ISSN: 1532-1827; 0007-0920

Online Volltext: dx.doi.org/ (Open Access)
Ahrens, M.; Hoiczyk, M.; Grabellus, Florian; Täger, Georg; Pöttgen, Christoph; Schuler, Martin; Bauer, Sebastian

Angiosarcomas of the adulthood - a large single center analysis

In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 254 - 254

ISSN: 0378-584X; 1423-0240
Aktas, B.; Kasimir-Bauer, Sabine; Kasper, Stefan; Derks, C.; Kimmig, Rainer; Schuler, Martin; Tewes, Mitra

Comparison of PIK3CA Hot Spot Mutations in the Primary Tumor or Metastases with PIK3CA Mutations or PIK3CA Over-Expression in Circulating Tumor Cells of Metastatic Breast Cancer Patients under Sequential Palliative Therapy

In: Cancer Research Jg. 71 (2011) Nr. Suppl. 24,

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Gauler, Thomas; Theegarten, Dirk; Parr, A.; Schuhr, I.; Schmid, Kurt Werner; Eberhardt, Wilfried; Schuler, Martin; Hoffmann, Andreas-Claudius

Decrease of circulating tumor cells associates with response to platinum-based chemotherapy in patients with non-small cell lung cancer, but not with small cell lung cancer

In: Journal of Thoracic Oncology Jg. 6 (2011) Nr. Suppl. 6, S. 1114

ISSN: 1556-1380; 1556-0864
Simon, S.; Grabellus, Florian; Täger, Georg; Treckmann, Jürgen-Walter; Schuler, Martin; Fletcher, J.; Bauer, Sebastian

Development of xenograft-based in vivo models of gastrointestinal stromal tumors

In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 253 - 253

ISSN: 0378-584X; 1423-0240
Livingstone, Elisabeth; Trarbach, Tanja; Zimmer, Lisa; Schuler, Martin; Schadendorf, Dirk

EGFR-Inhibitoren und Multityrosinkinaseinhibitoren : Interdisziplinäre Behandlung der kutanen Nebenwirkungen

In: Deutsche Medizinische Wochenschrift - DMW Jg. 136 (2011) Nr. 1-2, S. 39 - 44

ISSN: 1439-4413; 0012-0472; 1437-5982

Online Volltext: dx.doi.org/
Schmidt, Marcus; Petry, Ilka Brigitte; Böhm, Daniel; Lebrecht, Antje; Törne, Christian von; Gebhard, Susanne; Gerhold-Ay, Aslihan; Cotarelo, Cristina; Battista, Marco; Schormann, Wiebke; Freis, Evgenia; Selinski, Silvia; Ickstadt, Katja; Rahnenführer, Jörg; Sebastian, Martin; Schuler, Martin; Koelbl, Heinz; Gehrmann, Mathias; Hengstler, Jan G.

Ep-CAM RNA expression predicts metastasis-free survival in three cohorts of untreated node-negative breast cancer

In: Breast Cancer Research and Treatment Jg. 125 (2011) Nr. 3, S. 637 - 646

ISSN: 1573-7217; 0167-6806

Online Volltext: dx.doi.org/
Christoph, DanielC; Kasper, Stefan; Gauler, ThomasC; Breitenbücher, Frank; Engelhard, Marianne; Theegarten, Dirk; Pöttgen, Christoph; Hepp, Rodrigo; Peglow, Anja; Loewendick, Heike; Hirsch, FredR; Schuler, Martin; Eberhardt, Wilfried; Wohlschläger, Jeremias

Evaluation of Betav-Tubulin expression as novel predictive biomarker for clinical benefit from treatment with taxanes in non-small cell lung cancer

In: Journal of Thoracic Oncology Jg. 6 (2011) Nr. Suppl. 6, S. 1078

ISSN: 1556-0864; 1556-1380
Christoph, Daniel; Gauler, Thomas; Engelhard, M.; Theegarten, Dirk; Pöttgen, Christoph; Hepp, R.; Schuler, Martin; Hirsch, F.; Eberhardt, Wilfried; Wohlschläger, Jeremias

Evaluation of betaV-tubulin expression as novel predictive biomarker for clinical benefit from treatment with taxanes in non-small cell lung cancer (NSCLC)

In: European Journal of Cancer Jg. 47 (2011) Nr. Suppl. 4, S. 14

ISSN: 0959-8049
Becker, Silvan; Markova, Boyka; Wiewrodt, Rainer; Hoffarth, Sandra; Hähnel, Patricia S.; Pleiner, Sina; Schmidt, Lars Hennig; Breitenbücher, Frank; Schuler, Martin

Functional and Clinical Characterization of the Putative Tumor Suppressor WWOX in Non-small Cell Lung Cancer

In: Journal of Thoracic Oncology Jg. 6 (2011) Nr. 12, S. 1976 - 1983

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Breitenbücher, Frank; Hoffarth, S.; Gauler, Thomas; Stergar, S. L.; Kasper, Stefan; Kohler, J.; Worm, K.; Marten, A.; Schmid, Kurt Werner; Schuler, Martin

Highly sensitive detection of somatic epidermal growth factor receptor (EGFR) gene mutations in circulating tumor cells (CTC) from patients with non-small cell lung cancer treated with cisplatin/pemetrexed or afatinib

In: Journal of Thoracic Oncology Jg. 6 (2011) Nr. Suppl. 6, S. S956 - S957

ISSN: 1556-0864; 1556-1380
Christoph, DanielC; Wohlschläger, Jeremias; Neumann, Volker; Gauler, ThomasC; Pöttgen, Christoph; Peglow, Anja; Tannapfel, Andrea; Schuler, Martin; Hirsch, FredR; Eberhardt, Wilfried; Theegarten, Dirk

Impact of dihydrofolate reductase expression for clinical benefit from pemetrexed in malignant pleural mesothelioma

In: Journal of Thoracic Oncology Jg. 6 (2011) Nr. Suppl. 6, S. S1052 - S1053

ISSN: 1556-0864; 1556-1380
Philipps, E. S.; Mühlenberg, Thomas; Simon, S.; Ecken, S.; Grabellus, Florian; Täger, Georg; Schuler, Martin; Bauer, Sebastian

Inhibition of the Ras/Raf/MAPK-pathway in GIST : Therapeutic potential?

In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 235 - 235

ISSN: 0378-584X; 1423-0240
Lambertz, N.; Köhler, Johannes; Schulte, D.M.; Kühl, Hilmar; Wohlschläger, Jeremias; Hense, Jörg; Schuler, Martin; Müller, Oliver

Multivisceral systemic metastases from an intracranial anaplastic meningioma : A case report and review of literature

In: Clinical Neurology and Neurosurgery Jg. 113 (2011) Nr. 7, S. 592 - 595

ISSN: 0303-8467; 1872-6968

Online Volltext: dx.doi.org/
Köhler, Johannes; Schuler, Martin

Personalisierte medikamentöse Therapie des fortgeschrittenen nichtkleinzelligen Lungenkarzinoms : Der Pfeil des Wilhelm Tell?

In: Der Onkologe Jg. 17 (2011) Nr. 8, S. 702 - 708

ISSN: 1433-0415; 0947-8965

Online Volltext: dx.doi.org/
Kasper, Stefan; Breitenbücher, Frank; Even, A.; Pogorzelski, M.; Hoffarth, S.; Stergar, S. L.; Trarbach, Tanja; Schuler, Martin

Pharmacological Inhibition of NF-k and PLK-1 to the Opening of the RAS-mediated Resistance to anti-EGFR Antibody therapies in Colorectal cancer *

In: Der Internist Jg. 52 (2011) Nr. 6, S. 726 - 726

ISSN: 0020-9554
Christoph, Daniel; Schuler, Martin

Polo-like kinase 1 inhibitors in mono- and combination therapies : A new strategy for treating malignancies

In: Expert Review of Anticancer Therapy Jg. 11 (2011) Nr. 7, S. 1117 - 1132

ISSN: 1473-7140; 1744-8328

Online Volltext: dx.doi.org/
Christoph, DanielC; Mascaux, Celine; Wynes, MurryW; Asuncion, Bernadette; Wohlschläger, Jeremias; Theegarten, Dirk; Gauler, Thomas; Neumann, Volker; Pöttgen, Christoph; Tran, Cindy; Tannapfel, Andrea; Schuler, Martin; Eberhardt, Wilfried; Hirsch, FredR

Predictive value of thymidylate synthase and Folypoly-Glutamate Synthease for clinical benefit from pemetrexed in malignant pleural mesothelioma

In: Journal of Thoracic Oncology Jg. 6 (2011) Nr. Suppl. 6, S. S1092 - S1093

ISSN: 1556-0864; 1556-1380
Christoph, Daniel; Mascaux, C.; Wynes, M. W.; Reyna Asuncion, B.; Wohlschläger, Jeremias; Theegarten, Dirk; Gauler, Thomas; Schuler, Martin; Eberhardt, Wilfried; Hirsch, F. R.

Predictive value of thymidylate synthase and folylpoly-glutamate synthetase for clinical benefit from pemetrexed in malignant pleural mesothelioma

In: Journal of Clinical Oncology (JCO) Jg. 29 (2011) Nr. 15_suppl, S. 7024

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Scheulen, Max Ernst; Nokay, B.; Richly, Heike; Hoffmann, Andreas-Claudius; Kalkmann, J.; Stattaus, Jörg; Bornfeld, Norbert; Schuler, Martin; Hense, Jörg

Register trial of sorafenib (S) for patients (pts) with metastatic uveal melanoma (metUvMel)

In: European Journal of Cancer Jg. 47 (2011) Nr. Suppl. 4, S. S30

ISSN: 0959-8049

Online Volltext: dx.doi.org/
Schuler, Martin; Breitenbücher, Frank; Trarbach, Tanja; Brandau, Sven; Schmid, Kurt Werner; Kasper, Stefan

Simultaneous protection against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR-signaling blockade by oncogenic RAS

In: Journal of Clinical Oncology Jg. 29 (2011) Nr. Suppl. 4, S. 440

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schütt, Philipp; Stattaus, Jörg; Schuler, Martin

Solitärer Lungenrundherd - Weitere Abklärung erforderlich?

In: TumorDiagnostik & Therapie Jg. 32 (2011) Nr. 1, S. 33 - 37

ISSN: 1439-1279

Online Volltext: dx.doi.org/
Mühlenberg, Thomas; Simon, S.; Fletcher, J. A.; Grabellus, Florian; Täger, Georg; Treckmann, Jürgen-Walter; Schuler, Martin; Bauer, Sebastian

The BH3-mimetic ABT-263 enhances the apoptotic response of GIST cells to KIT-inhibitory treatments

In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 254

ISSN: 0378-584X; 1423-0240
Hoiczyk, M.; Grabellus, Florian; Täger, Georg; Schuler, Martin; Bauer, Sebastian

Trabectedin in heavily pretreated and elderly metastatic soft tissue sarcomas - a single center experience

In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 237 - 237

ISSN: 0378-584X; 1423-0240
Koeppen, Susanne; Hense, Jörg; Nolte, K. W.; Weis, J.; Schuler, Martin

Treatable Bortezomib-related peripheral neuropathy in multiple myeloma

In: Journal of Peripheral Nervous Systems Jg. 16 (2011) Nr. Suppl. 3, S. 68

ISSN: 1085-9489; 1529-8027
Christoph, Daniel; Wittkowski, Lukas; Stattaus, Jörg; Pöttgen, Christoph; Keyvani, Kathy; Gauler, Thomas; Schuler, Martin; Eberhardt, Wilfried

Very Late and Isolated Leptomeningeal Relapse of a Pulmonary Adenocarcinoma Presenting as Dementia

In: Onkologie Jg. 34 (2011) Nr. 6, S. 316 - 320

ISSN: 1423-0240

Online Volltext: dx.doi.org/
Schütt, Philipp; Müller, Stefan; Matuszczyk, Anna; Schmid, Kurt Werner; Bockisch, Andreas; Schuler, Martin; Mann, Klaus

Zielgerichtete Therapie für Patienten mit Schilddrüsenkarzinom

In: TumorDiagnostik & Therapie Jg. 32 (2011) Nr. 5, S. 269 - 276

ISSN: 1439-1279

Online Volltext: dx.doi.org/
Schmidt, Martina; Scheulen, Max Ernst; Dittrich, C.; Obrist, P.; Marschner, N.; Dirix, L.; Schmidt, M.; Rüttinger, D.; Schuler, Martin; Reinhardt, C.; Awada, A.

An open-label, randomized phase II study of adecatumumab, a fully human anti-EpCAM antibody, as monotherapy in patients with metastatic breast cancer

In: Annals of Oncology Jg. 21 (2010) Nr. 2, S. 275 - 282

ISSN: 0923-7534; 1569-8041

Online Volltext: dx.doi.org/
Schuler, Martin; Uttenreuther-Fischer, M. M.; Piccart-Gebhart, M. J.; Harbeck, N.; on behalf of the study group and trial team

BIBW 2992, a novel irreversible EGFR/HER1 and HER2 tyrosine kinase inhibitor, for the treatment of patients with HER2-negative metastatic breast cancer after failure of no more than two prior chemotherapies

In: Journal of Clinical Oncology (JCO) Jg. 28 (2010) Nr. Suppl. 15, S. 1065

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Petry, I. B.; Fieber, E.; Schmidt, Marcus; Gehrmann, M.; Gebhard, S.; Hermes, M.; Schormann, W.; Selinski, S.; Freis, E.; Schwender, H.; Brulport, M.; Ickstadt, K.; Rahnenführer, J.; Maccoux, L.; West, J.; Kölbl, H.; Schuler, Martin; Hengstler, J. G.

ERBB2 Induces an Antiapoptotic Expression Pattern of Bcl-2 Family Members in Node-Negative Breast Cancer

In: Clinical Cancer Research Jg. 16 (2010) Nr. 2, S. 451 - 460

ISSN: 1557-3265; 1078-0432

Online Volltext: dx.doi.org/
Mühlenberg, Thomas; Fletcher, J. A.; Grabellus, Florian; Schuler, Martin; Bauer, Sebastian

Effective therapeutic sensitization of gastrointestinal stromal tumors by a BH3 mimetic

In: European Journal of Cancer / EJC Supplements Jg. 8 (2010) Nr. 7, S. 69 - 70

ISSN: 1359-6349; 1878-1217

Online Volltext: dx.doi.org/
Köhler, Jens; Breitenbücher, Frank; Schuler, Martin

Individualisierte Therapie für Patienten mit fortgeschrittenen Lungenkarzinomen

In: TumorDiagnostik & Therapie Jg. 31 (2010) Nr. 2, S. 79 - 87

ISSN: 1439-1279; 0722-219X

Online Volltext: dx.doi.org/
Nguyen, B.; Grabellus, Florian; Hoiczyk, M.; Täger, Georg; Schuler, Martin; Bauer, Sebastian

Long-term follow-up of patients with GIST undergoing metastasectomy in the era of imatinib (IM)

In: Journal of Clinical Oncology (JCO) Jg. 28 (2010) Nr. Suppl. 15, S. 10047

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Hoffmann, Andreas-Claudius; Wild, Peter; Leicht, Christina; Bertz, Simone; Danenberg, Kathleen D.; Danenberg, Peter V.; Stöhr, Robert; Stöckle, Michael; Lehmann, Jan; Schuler, Martin; Hartmann, Arndt

MDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy

In: Neoplasia: An International Journal for Oncology Research Jg. 12 (2010) Nr. 8, S. 628 - 636

ISSN: 1522-8002; 1476-5586

Online Volltext: dx.doi.org/ (Open Access)
Waldner, Maximilian J.; Wirtz, Stefan; Becker, Christoph; Seidel, Daniel; Tubbe, Ingrid; Cappel, Kyra; Hähnel, Patricia S.; Galle, Peter R.; Schuler, Martin; Neurath, Markus F.

Perforin deficiency attenuates inflammation and tumor growth in colitis-associated cancer

In: Inflammatory Bowel Diseases Jg. 16 (2010) Nr. 4, S. 559 - 567

ISSN: 1078-0998; 1536-4844

Online Volltext: dx.doi.org/
Schütt, Philipp; Schütt, Birgit; Switala, Magdalena; Bauer, Sebastian; Stamatis, Georgios; Opalka, Bertram; Eberhardt, Wilfried; Schuler, Martin; Horn, Peter; Rebmann, Vera

Prognostic relevance of soluble human leukocyte antigen-G and total human leukocyte antigen class I molecules in lung cancer patients

In: Human Immunology Jg. 71 (2010) Nr. 5, S. 489 - 495

ISSN: 0198-8859; 1879-1166

Online Volltext: dx.doi.org/
Advani, Anjali; Coiffier, Bertrand; Czuczman, Myron S.; Dreyling, Martin; Foran, James; Gine, Eva; Gisselbrecht, Christian; Ketterer, Nicolas; Nasta, Sunita; Rohatiner, Ama; Schmidt-Wolf, Ingo G. H.; Schuler, Martin; Sierra, Jorge; Smith, Mitchell R.; Verhoef, Gregor; Winter, Jane N.; Boni, Joseph; Vandendries, Erik; Shapiro, Mark; Fayad, Luis

Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma : results of a phase I study

In: Journal of Clinical Oncology (JCO) Jg. 28 (2010) Nr. 12, S. 2085 - 2093

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Köhler, J.; Schuler, Martin

Targeted Therapies in der Behandlung solider und hämatologischer Neoplasien

In: TumorDiagnostik & Therapie Jg. 31 (2010) Nr. 3, S. 133 - 142

ISSN: 1439-1279; 0722-219X

Online Volltext: dx.doi.org/
Sebastian, Martin; Reck, Martin; Waller, Cornelius F.; Kortsik, Cornelius; Frickhofen, Norbert; Schuler, Martin; Fritsch, Holger; Gaschler-Markefski, Birgit; Hanft, Gertraud; Munzert, Gerd; Pawel, Joachim von

The efficacy and safety of BI 2536, a novel Plk-1 inhibitor, in patients with stage IIIB/IV non-small cell lung cancer who had relapsed after, or failed, chemotherapy : Results from an open-label, randomized phase ii clinical trial

In: Journal of Thoracic Oncology Jg. 5 (2010) Nr. 7, S. 1060 - 1067

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Bauer, Sebastian; Mühlenberg, Thomas; Leahy, Michael; Hoiczyk, Mathias; Gauler, Thomas; Schuler, Martin; Looijenga, Leendert

Therapeutic Potential of Mdm2 Inhibition in Malignant Germ Cell Tumours

In: European Urology Jg. 57 (2010) Nr. 4, S. 679 - 687

ISSN: 0302-2838; 1421-993X

Online Volltext: dx.doi.org/
Hoffmann, Andreas-Claudius; Gauler, Thomas; Parr, A.; Eberhardt, Wilfried; Schuler, Martin

Use of ERCC1 expression levels in circulating tumor cells to predict to response to platinum-based chemotherapy in patients with non-small cell lung cancer

In: Journal of Clinical Oncology (JCO) Jg. 28 S (2010) Nr. 15, S. Abstract7512

ISSN: 0732-183X; 1527-7755
Mühlenberg, Thomas; Zhang, Yixiang; Wagner, Andrew J.; Grabellus, Florian; Bradner, James; Täger, Georg; Lang, Hauke; Taguchi, Takahiro; Schuler, Martin; Fletcher, Jonathan A.; Bauer, Sebastian

Inhibitors of deacetylases suppress oncogenic KIT signaling, acetylate HSP90, and induce apoptosis in gastrointestinal stromal tumors

In: Cancer Research Jg. 69 (2009) Nr. 17, S. 6941 - 6950

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/ (Open Access)
Thaler, Sonja; Hähnel, Patricia S.; Schad, Arno; Dammann, Reinhard; Schuler, Martin

RASSF1A mediates p21Cip1/Waf1- dependent cell cycle arrest and senescence through modulation of the Raf-MEK-ERK pathway and inhibition of Akt

In: Cancer Research Jg. 69 (2009) S. 1748 - 1757

ISSN: 1538-7445; 0008-5472

Online Volltext
Hähnel, Patricia S.; Thaler, Sonja; Antunes, Edite; Huber, Christoph; Theobald, Matthias; Schuler, Martin

Targeting AKT signaling sensitizes cancer to cellular immunotherapy

In: Cancer Research Jg. 68 (2008) S. 3899 - 3906

ISSN: 1538-7445; 0008-5472

Online Volltext
Stolz, Claudia; Hess, Georg; Hähnel, Patricia S.; Grabellus, Florian; Hoffarth, Sandra; Schmid, Kurt Werner; Schuler, Martin

Targeting Bcl-2 family proteins modulates the sensitivity of B-cell lymphoma to rituximab-induced apoptosis

In: Blood Jg. 112 (2008) Nr. 8, S. 3312 - 3321

ISSN: 1528-0020; 0006-4971

Online Volltext: dx.doi.org/ Online Volltext (Open Access)
Bargou, R.; Leo, E.; Zugmeier, G.; Klinger, M.; .Goebeler, M.; Knop, S.; Noppeney, Richard; Viardot, A.; Hess, G.; Schuler, Martin; Einsele, H.; Brandl, C.; Wolf, A.; Kirchinger, P.; Klappers, P.; Schmidt, Markus; Riethmüller, G.; Reinhardt, C.; Baeuerle, P.A.; Kufer, P.

Tumor regression in cancer patients by very low doses of a T cell-engaging antibody.

In: Science Jg. 5891 (2008) Nr. 321, S. 974 - 977
Hoffarth, Sandra; Zitzer, Alexander; Wiewrodt, Rainer; Hähnel, Patricia S.; Beyer, Vera; Kreft, Andreas; Biesterfeld, Stefan; Schuler, Martin

pp32/PHAPI determines the apoptosis response of non-small-cell lung cancer

In: Cell Death and Differentiation Jg. 15 (2008) S. 161 - 170

ISSN: 1350-9047; 1476-5403

Online Volltext

Vorworte / Nachworte

Reinmuth, Niels; Schuler, Martin

Shall we use steroids when treating patients with lung cancer with checkpoint inhibitors?

In: European Journal of Cancer (EJC) Jg. 145 (2021) S. 255 - 257

ISSN: 1879-0852; 0959-8049; 1879-2995

Online Volltext: dx.doi.org/
Schuler, Martin

Inhibiting fibroblast growth factor receptors in cancer – the next generation

In: Annals of Oncology Jg. 31 (2020) Nr. 10, S. 1285 - 1286

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Höffken, K.; Heiss, M.M.; Schuler, Martin

Tumorimmunologie : Beginn einer neuen Ära?

In: Der Onkologe Jg. 18 (2012) S. 754 - 756

ISSN: 1433-0415; 0947-8965

Online Volltext: dx.doi.org/

Abstracts

Richlitzki, Cedric; Pöttgen, Christoph; Wiesweg, Marcel; Metzenmacher, Martin; Guberina, Nika; Gauler, Thomas; Hautzel, Hubertus; Eberhardt, Wilfried; Darwiche, Kaid; Theegarten, Dirk; Bölükbas, Servet; Schuler, Martin; Stuschke, Martin; Guberina, Maja

Kreuzvalidierte Prognoseparameter C-reaktives Protein und Blutbild-Parameter im Verlauf der kurativ intendierten Radiochemotherapie bei Patienten mit nichtkleinzelligem Lungenkarzinom (NSCLC) im Stadium IIIA-C

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S100 - S101

ISSN: 1439-099X; 0179-7158

Online Volltext: dx.doi.org/ (Open Access)
Stuschke, Martin; Pöttgen, Christoph; Gauler, Thomas; Cordes, Sebastian; Metzenmacher, Martin; Brintrup, Diana Luetke; Guberina, Maja; Filiz, Özkan; Darwiche, Kaid; Schuler, Martin; Jöckel, Karl-Heinz; Aigner, Clemens; Stamatis, Georgios; Eberhardt, Wilfried

Langzeitüberleben und konkurrierende Risiken von Patienten einer randomisierten Studie zur defnitiven vs. neoadjuvanten Radiochemotherapie + Resektion mit einem nach der Induktion resektablen NSCLC im Stadium III

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S7 - S8

ISSN: 1439-099X; 0179-7158

Online Volltext: dx.doi.org/ (Open Access)
Guberina, Maja; Pöttgen, Christoph; Wiesweg, Marcel; Metzenmacher, Martin; Richlitzki, Cedric; Plönes, Till; Guberina, Nika; Forsting, Michael; Herrmann, Ken; Gauler, Thomas; Hoffmann, Christian; Theegarten, Dirk; Darwiche, Kaid; Garcia, Alina Santiago; Stuschke, Martin; Schuler, Martin

Long-term Survival in Patients with oligometastatic Lung Cancer (cT4 or cN2-3, cM1a-c) after thoracic Chemoradiation, Metastasis-directed and Systemic Therapy compared with the Outcome in locally advanced Lung Cancer (cT4 or cN2-3, cM0)

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S101 - S102

ISSN: 1439-099X; 0179-7158

Online Volltext: dx.doi.org/
Fink, M.; Schmidt, K.; Tewes, Mitra; Schuler, Martin; Müller, B. W.; Schadendorf, Dirk; Scherbaum, Norbert; Kowalski, A.; Skoda, E.-M.; Teufel, Martin;

RCT to Test the Efficacy of an EEG Neurofeedback Intervention in Cancer Patients and Cancer Survivors
Deutscher Kongress für Psychosomatische Medizin und Psychotherapie, 03.-05.05.2023, Berlin,

In: Zeitschrift für Psychosomatische Medizin und Psychotherapie Jg. 69 (2023) Nr. 2, S. 148 - 149

ISSN: 1438-3608; 2196-8349

Online Volltext: dx.doi.org/
Lanzafame, H.; Hirmas, N.; Schuler, Martin; Darwiche, Kaid; Eberhardt, Wilfried E. E.; Aigner, Clemens; Stuschke, Martin; Kessler, Lukas; Pabst, K. M.; Barbato, F.; Rischpler, Christoph; Hautzel, H.; Herrmann, Ken; Fendler, Wolfgang;

68GA-FAPI PET/CT in the evaluation of Non-Small Cell Lung Cancer (NSCLC)
EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022, Barcelona, Spain,

In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 49 (2022) Nr. Supplement 1, S. S107

ISSN: 1619-7089; 1619-7070; 0340-6997; 1432-105X

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin H. H.; Cuppens, K.; Ploenes, T.; Vanbockrijck, M.; Wiesweg, Marcel; Darwiche, Kaid; Schramm, Alexander; Maes, B.; Hegedus, B.; Schildhaus, Hans-Ulrich; Hautzel, H.; Theegarten, Dirk; Baas, P.; Hartemink, K.; Du Pont, B.; Aigner, Clemens;

A randomized, multicentric phase II study of preoperative nivolumab plus relatlimab or nivolumab in patients with resectable non-small cell lung cancer (NEOpredict-Lung)
ESMO Congress 2022, 9 - 13 September 2022, Paris, France,

In: Annals of Oncology Jg. 33 (2022) Nr. Supplement 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S1404

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Petzold, A.; Dujardin, P.; Oeck, S.; Wiesweg, Marcel; Hegedüs, B.; Schuler, Martin; Grüner, Barbara M.; Schramm, Alexander

Combining Patient-Derived Xenografts and Barcoding Technology to Evaluate Response to Targeted Therapies in ALK+NSCLC

In: Journal of Thoracic Oncology Jg. 17 (2022) Nr. 9, S. 611

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Schuler, Martin; Loriot, Y.; Iyer, G.; Witt, O.; Doi, T.; Qin, S.; Tabernero, J.; Reardon, D. A.; Massard, C.; Palmer, D. H.; Lugowska, I.; Coward, J.; Corassa, M.; Stuyckens, K.; Liao, H.; Najmi, S.; Hammond, C.; Santiago-Walker, A. E.; Sweiti, H.; Pant, S.;

Entitäten-unabhängige Sicherheit und Wirksamkeit von Erdafitinib bei Patienten mit fortgeschrittenen soliden Tumoren mit präspezifizierten genomischen FGFR- Aberrationen (RAGNAR Interimanalyse)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,

In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 27 - 28

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Hegedüs, Luca; Okumus, Ö.; Mairinger, Fabian; Plönes, Till; Reuter, Sebastian; Schuler, Martin; Theegarten, Dirk; Bankfalvi, Agnes; Aigner, Clemens; Hegedüs, Balazs

Expression and SN38 Antitumor Activity in Malignant Pleural Mesothelioma Cells

In: Journal of Thoracic Oncology Jg. 17 (2022) Nr. 9, S. 118

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Pogorzelski, M.; Fendler, Wolfgang; Berliner, C.; Hussain, T.; Lang, Stephan; Ting, Saskia; Schmid, Kurt Werner; Schildhaus, Hans-Ulrich; Gauler, Thomas; Stuschke, Martin; Laue, K.; Herrmann, Ken; Grünwald, V.; Schuler, Martin; Kasper-Virchow, S.;

Immuntherapie eines Mikrosatelliten-instabilen metastasierten Talgdrüsenkarzinoms der Glandula submandibularis mit Pembrolizumab
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,

In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 230 - 231

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Tan, D. S.; Shimizu, T.; Cassier, P. A.; et al.;

KontRASt-01 : eine Phase Ib/II Dosiseskalationsstudie von JDQ443 in Patienten mit fortgeschrittenen, KRAS G12C-mutierten soliden Tumoren
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie 07. bis 10. Oktober 2022, Wien, Austria,

In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 29

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Eberhardt, Wilfried; Pöttgen, Christoph; Gauler, Thomas; Schulte, C; Friedel, G.; Kopp, H.-G.; Fischer, B.; Schmidberger, H.; Kimmich, M.; Budach, W.; Cordes, S.; Metzenmacher, M.; de Los Rios, R. Hepp; Spengler, W.; De Ruysscher, D.; Belka, C.; Welter, S.; Brintrup, D. Luetke; Guberina, M.; Oezkan, F.; Darwiche, Kaid; Schuler, Martin; Jöckel, Karl-Heinz; Aigner, Clemens; Stamatis, Georgios; Stuschke, Martin

Long-term Survival and Competing Risks of Death in the ESPATUE Randomized Phase-III Trial in Stage III NSCLC

In: Journal of Thoracic Oncology Jg. 17 (2022) Nr. 9, S. 65

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Miura, Satoru; Schuler, Martin; Popat, Sanjay; Park, Keunchil; Passaro, Antonio; De Marinis, Filippo; Solca, Flavio; Märten, Angela; Kim, Edward S.; Chih-Hsin Yang, James;

MO29-3 A database of 1023 patients with NSCLC and uncommon EGFR mutations treated with afatinib : Focus on Asian patients
The 19th Annual Meeting of JSMO (Japanese Society of Medical Oncology), 17.–19.02.2022, Kyoto,

In: Annals of Oncology Jg. 33 (2022) Nr. Suppl. 6: 2022 the Japanese Society of Medical Oncology Annual Meeting 17–19 February 2022, Kyoto, Japan, S. 500

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Okumus, O.; Mardanzai, K.; Ploenes, T.; Theegarten, Dirk; Darwiche, Kaid; Schuler, Martin; Nensa, Felix; Hautzel, H.; Stuschke, Martin; Hegedues, B.; Aigner, Clemens

Preoperative PET-SUVmax and Volume Based PET Metrics of the Tumor Fail to Predict Nodal Upstaging in Early-Stage Lung Cancer

In: Journal of Thoracic Oncology Jg. 17 (2022) Nr. 9, S. 203

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Maier, D.; Vehreschild, J. J.; Uhl, B.; Grünwald, V.; Hadaschik, Boris; Palm, S.; Stuschke, Martin; Esins, M.; Ressing, F.; Schuler, Martin; Serve, H.; et al.;

Profil der multizentrischen Kohorte der Klinischen Kommunicationsplattform des Deutschen Konsortiums für Translationale Krebsforschung (DKTK)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,

In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 13

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Guberina, M.; Pöttgen, Christoph; Guberina, N.; Gauler, Thomas; Metzenmacher, M.; Wiesweg, Marcel; Richlitzki, C.; Plönes, T.; Forsting, Michael; Wetter, Axel; Herrmann, Ken; Hautzel, H.; Darwiche, Kaid; Theegarten, Dirk; Aigner, Clemens; Schuler, Martin; Eberhardt, Wilfried E. E.; Stuschke, Martin;

Robuste und lang-andauernde Wirksamkeit der Durvalumab-Konsolidierung bei NSCLC im Stadium III nach Induktionschemotherapie und definitiver Radiochemotherapie : Fokus auf Behandlungsauswahl und prognostische Faktoren
28. Kongress der Deutschen Gesellschaft für Radioonkologie ; DEGRO 2022 ; 26. bis 28.05.2022, Stuttgart, Germany,

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 198 (2022) Nr. Supplement 1, S. S15

ISSN: 1439-099X; 0179-7158

Online Volltext: dx.doi.org/ (Open Access)
Hamacher, R.W.; Pabst, K.M.; Kessler, Lukas; Costa, Pedro Fragoso; Ferdinandus, J.; Weber, Manuel; Lippert, M.; Lückerath, Katharina; Hirmas, N.; Kostbade, K.; Mavroeidi, I.A.; Schuler, Martin H. H.; Ahrens, M.; Rischpler, Christoph; Bauer, Sebastian; Herrmann, Ken; Siveke, Jens T.; Fendler, Wolfgang P.;

Safety and efficacy of [90Y]Y-FAPI-46 radioligand therapy in patients with advanced sarcomas and other cancer entities
ESMO Congress 2022, 9 - 13 September 2022, Paris, France,

In: Annals of Oncology Jg. 33 (2022) Nr. Supplement 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S1231 - S1232

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Martens, U.M.; Schröder, J.; Sellmann, Ludger; Reiser, M.; Frank-Gleich, S.; Decker, T.; Schneeweiss, A.; Schuler, Martin; Grebhardt, S.; Woerner, S.; Zacharias, S.; Marschner, N.W.; Kasenda, B.; Vannier, C.

Second interim analysis of INFINITY : A registry on decision making and clinical impact of biomarker-driven precision oncology in routine clinical practice

In: Annals of Oncology Jg. 33 (2022) S. 575 - S576

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/
Johnson, M.L.; de Langen, A.J.; Waterhouse, D.M.; Mazieres, J.; Dingemans, A-M.C.; Mountzios, G.; Pless, M.; Wolf, J.; Schuler, Martin; Lena, H.; Skoulidis, F.; Okamoto, I.; Kim, S-W.; Linardou, H.; Novello, S.; Chen, Y.; Solomon, B.; Obiozor, C.; Wang, Y.; Paz-Ares, L.;

Sotorasib versus docetaxel for previously treated non-small cell lung cancer with KRAS G12C mutation : CodeBreaK 200 phase III study
ESMO Congress 2022, 9 - 13 September 2022, Paris, France,

In: Annals of Oncology Jg. 33 (2022) Nr. Supplement 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S1417 - S1418

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Tüns, A.I.; Ho, C.S.L.; Schildhaus, Hans-Ulrich; Wiesweg, Marcel; Grüner, Barbara M.; Hegedüs, B.; Schuler, Martin; Schramm, Alexander; Oeck, S.

Targeting SHP2 Reverts Oncogenic Mediated Resistance to KRAS-G12C Inhibition

In: Journal of Thoracic Oncology Jg. 17 (2022) Nr. 9, S. S586 - S587

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Loriot, Yohann; Schuler, Martin; Iyer, Gopa; Witt, Olaf; Doi, Toshihiko; Qin, Shukui; Tabernero, Josep; Reardon, David A.; Massard, Christophe; Palmer, Daniel; Lugowska, Iwona; Coward, Jermaine; Corassa, Marcelo; Stuyckens, Kim; Liao, Huimin; Najmi, Saltanat; Hammond, Constance; Santiago-Walker, Ademi E.; Sweiti, Hussein; Pant, Shubham

Tumor agnostic efficacy and safety of erdafitinib in patients (pts) with advanced solid tumors with prespecified fibroblast growth factor receptor alterations (FGFRalt) in RAGNAR : Interim analysis (IA) results

In: Journal of Clinical Oncology (JCO) Jg. 40 (2022) Nr. 16_Suppl., S. 3007

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Hu, M.I.; Subbiah, V.; Mansfield, A.S.; Taylor, M.; Schuler, Martin H.H.; Zhu, V.; Hadoux, J.; Curigliano, G.; Wirth, L.J.; Garralda, E.; Adkins, D.R.; Godbert, Y.; Ahn, M-J.; Cassier, P.A.; Cho, B.C.; Lin, C-C.; Barata, T.; Zalutskaya, A.; Scalori, A.; Brose, M.S.;

Updated ARROW data : Pralsetinib in patients (pts) with advanced or metastatic RET-altered thyroid cancer (TC)
ESMO Congress 2022, 9 - 13 September 2022, Paris, France,

In: Annals of Oncology Jg. 33 (2022) Nr. Supplement 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S1298 - S1299

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Martens, U.; Schröder, J.; Sellmann, Ludger; Reiser, M.; Frank-Gleich, S.; Decker, T.; Schneeweiss, A.; Schuler, Martin; Grebhardt, S.; Woerner, S.; Zacharias, S.; Marschner, N.; Kasenda, B.; Vannier, C.;

Zweite Interimsanalyse zu INFINITY : ein Register zur Entscheidungsfindung in der Biomarker-basierten Präzisionsonkologie und deren klinische Bedeutung
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,

In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 11 - 12

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Kessler, Lukas; Ferdinandus, J.; Costa, P. F.; Weber, Manuel; Hirmas, N.; Kostbade, K.; Bauer, Sebastian; Dirksen, U.; Zarrad, F.; Nader, M.; Grafe, Hong; Chodyla, M.; Milosevic, A.; Umutlu, Lale; Schuler, Martin; Ahrens, M.; Podleska, Lars E.; Schildhaus, Hans-Ulrich; Rischpler, Christoph; Siveke, Jens T.; Herrmann, Ken; Fendler, Wolfgang P.; Hamacher, R.;

A novel theranostic approach for sarcoma : Insights on diagnostic and therapeutic use of FAP-radioligands
Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,

In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 11 - 12

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Melero, Ignacio; Calvo, Emiliano; Goebeler, Maria-Elisabeth; Garralda, Elena; Dummer, Reinhard; Rodríguez-Ruiz, María; Miguel, Maria de; Sayehli, Cyrus Michael; Casal, Guzman Alonso; Ramelyte, Egle; Schuler, Martin; Gromke, Tanja; Sanmamed, Miguel; Moreno, Irene; Bargou, Ralf; Lostes, Maria; Maul, Julia-Tatjana; Eggenschwiler, Corinne; Richly, Heike; Fettes, Petra; Klar, Kathrin; Schuberth-Wagner, Christine; Haake, Markus; Wischhusen, Jörg; Leo, Eugen;

A phase I, first-in-human clinical trial of the GDF-15 neutralizing antibody CTL-002 in subjects with advanced stage solid tumors (Acronym: GDFATHER)
SITC 36th Anniversary Annual Meeting (SITC 2021), 10-14 November 2021, Washington & virtually,

In: Journal for ImmunoTherapy of Cancer Jg. 9 (2021) Nr. Suppl. 2, S. A536 - A536

ISSN: 2051-1426

Online Volltext: dx.doi.org/ (Open Access)
Melero, Ignacio; Calvo, Emiliano; Dummer, Reinhard; Garralda, Elena; Schuler, Martin; Goebeler, Maria-Elisabeth; Bargou, Ralf C.; Gromke, Tanja; Tabernero, Josep; Ramelyte, Egle; De Miguel, Maria; Sanmamed, Miguel F.; Rodriguez-Ruiz, Maria E.; Fettes, Petra; Klar, Kathrin; Ruediger, Manfred; Schuberth-Wagner, Christine; Haake, Markus; Wischhusen, Joerg; Leo, Eugen;

A phase I, first-in-human clinical trial of the GDF-15 neutralizing antibody CTL-002 in subjects with advanced-stage solid tumors (ACRONYM: GDFATHER).
2021 Genitourinary Cancers Symposium, 11 - 13 Feb 2021, online,

In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_suppl, S. TPS2658

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Pant, Shubham; Tabernero, Josep; Massard, Christophe; Iyer, Gopa; Witt, Olaf; Doi, Toshihiko; Qin, Shukui; Lu-Emerson, Christine; Hargrave, Darren R.; García-Corbacho, Javier; Little, Shonda Marie; Xia, Qi; Santiago-Walker, Ademi E.; Moy, Christopher; Hammond, Constance; Sweiti, Hussein; Schuler, Martin;

A phase II open-label study in adult and adolescent patients (pts) with advanced solid tumors harboring fibroblast growth factor receptor (FGFR) gene alterations
2021 Gastrointestinal Cancers Symposium, 15-17 January 2021, online,

In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 3, Supplement, S. TPS480

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Yang, J.Y.C-H.; Schuler, Martin; Popat, Sanjay; Miura, Satoru; Park, Kyungrae; Passaro, Antonio; de Marinis, Filippo; Solca, Flavio F.; Märten, Angela; Kim, Edward S.

Afatinib for the treatment of NSCLC with uncommon EGFR mutations : An updated database of 1023 cases

In: Annals of Oncology Jg. 32 (2021) Nr. Suppl. 5, S. 965

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Subbiah, Vivek; Cassier, Philippe A.; Siena, Salvatore; Alonso, Guzman; Paz-Ares, Luis G.; Garrido, Pilar; Nadal, Ernest; Curigliano, Giuseppe; Vuky, Jacqueline; Lopes, Gilberto; Kalemkerian, Gregory Peter; Bowles, Daniel W.; Seetharam, Mahesh; Chang, Jianhua; Zhang, Hui; Ye, Chaoyang; Green, Jennifer; Zalutskaya, Alena; Schuler, Martin; Fan, Yun

Clinical activity and safety of the RET inhibitor pralsetinib in patients with RET fusion-positive solid tumors : Update from the ARROW trial

In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 3079 - 3079

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Subbiah, Vivek; Hu, Mimi I-Nan; Gainor, Justin F.; Mansfield, Aaron Scott; Alonso, Guzman; Taylor, Matthew H.; Zhu, Viola Weijia; Garrido, Pilar; Amatu, Alessio; Doebele, Robert C; Cassier, Philippe; Keam, Bhumsuk; Schuler, Martin; Zhang, Hui; Clifford, Corinne; Palmer, Michael; Green, Jennifer; Turner, Christopher D.; Curigliano, Giuseppe;

Clinical activity of the RET inhibitor pralsetinib (BLU-667) in patients with RET fusion–positive solid tumors
2021 Gastrointestinal Cancers Symposium, 15-17 January 2021, online,

In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 3, Supplement, S. 467 - 467

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Guberina, M.; Herrmann, Ken; Pöttgen, Christoph; Guberina, N.; Hoffmann, C.; Ploenes, T.; Gauler, Thomas; Wetter, Axel; Umutlu, Lale; Hautzel, H.; Theegarten, Dirk; Schuler, Martin; Eberhardt, Wilfried; Metzenmacher, M.; Wiesweg, Marcel; Aigner, Clemens; Darwiche, Kaid; Karpf-Wissel, Rüdiger; Stuschke, Martin

EBUS-TBNA and [F-18] FDG-PET/CT for precise Target Volume Definition prior to Chemoradiotherapy : Lymphonodular Spreading Patterns in Stage III NSCLC

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 197 (2021) Nr. Suppl. 1, S. 142

ISSN: 1439-099X; 0179-7158
Decker, T.; Fasching, P.A.; Nusch, A.; Hartkopf, A.; Heinrich, B.J.; Kurbacher, C.M.; Fuchs, R.; Tesch, H.; Krabisch, P.; Huober, J.; Kümmel, S.; Brucker, S.Y.; Janni, W.; Schneeweiss, A.; Schuler, Martin; Fehm, T.N.; Lüftner, D.; C. Quiering; Kreuzeder, J.; Reinisch, M.

Efficacy and safety of ribociclib (RIB) in combination with letrozole (LET) in patients with estrogen receptor–positive advanced breast cancer (ABC) : Secondary and exploratory results of phase 3b RIBECCA study

In: Annals of Oncology Jg. 32 (2021) Nr. Suppl. 5, S. 467 - S468

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Pogorzelski, M.; Lauri, F.; Hilser, T.; Hense, Jörg; Ting, Saskia; Kansy, B.; Gauler, Thomas; Stuschke, Martin; Schmid, Kurt Werner; Lang, Stephan; Zaun, G.; Grünwald, V.; Schuler, Martin; Kasper, Stefan

Efficacy of immunotherapy (IO) and subsequent systemic treatment after failure of IO in patients with recurrent or metastatic head and neck cancer in a real-world setting

In: Annals of Oncology Jg. 32 (2021) Nr. Suppl. 5, S. 812

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Martens, U.; Schröder, J.; Sellmann, Ludger; Frank-Gleich, S.; Zaiss, M.; Decker, T.; Schneeweiss, A.; Schuler, Martin; Grebhardt, S.; Vannier, C.; Marschner, N.; Kasenda, B.;

First interim analysis of INFINITY : A registry on decision making and clinical impact of biomarker-driven precision oncology in routine clinical practice
Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,

In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 295

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Müller, S.; Fink, M.; Schuler, Martin; Hense, Jörg; Przyborek, M.; Teufel, Martin; Tewes, Mitra;

Influence of external and self-assessment in symptom burden of cancer patients in a palliative care outpatient clinic of a Comprehensive Cancer Center
Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,

In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 92

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Ferdinandus, J.; Costa Fragoso, P.; Kessler, Lukas; Weber, Manuel; Hirmas, N.; Kostbade, K.; Bauer, Sebastian; Schuler, Martin; Ahrens, M.; Schildhaus, Hans-Ulrich; Rischpler, Christoph; Siveke, Jens; Herrmann, Ken; Fendler, Wolfgang; Hamacher, R.

Initial clinical experience with [Y-90]Y-FAPI-46 radioligand therapy for advanced stage solid tumors

In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 48 (2021) Nr. Suppl. 1, S. 290

ISSN: 1619-7089; 1619-7070; 0340-6997; 1432-105X
Skoulidis, Ferdinandos; Li, Bob T.; Govindan, Ramaswamy; Dy, Grace K.; Shapiro, Geoffrey; Bauml, Joshua; Schuler, Martin; Addeo, Alfredo; Kato, Terufumi; Besse, Benjamin; Anderson, Abraham; Ang, Agnes; Ngarmchamnanrith, Gataree; Tran, Qui; Velcheti, Vamsidhar

Overall survival and exploratory subgroup analyses from the phase 2 CodeBreaK 100 trial evaluating sotorasib in pretreated KRAS p.G12C mutated non-small cell lung cancer

In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 9003 - 9003

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Massard, Christophe; Pant, Shubham; Iyer, Gopa; Schuler, Martin; Witt, Olaf; Qin, Shukui; Tabernero, Josep; Doi, Toshihiko; Hargrave, Darren R.; Hammond, Constance; Little, Shonda Marie; Xia, Qi; Cao, Jing; Santiago-Walker, Ademi E.; Sweiti, Hussein

Preliminary results of molecular screening for FGFR alterations (alts) in the RAGNAR histology-agnostic study with the FGFR-inhibitor (FGFRi) erdafitinib

In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 4081 - 4081

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Kasper, Stefan; Goetze, Thorsten Oliver; Stintzing, Sebastian; Hofheinz, Ralf Dieter; Sinn, Marianne; Dechow, Tobias Nicolaas; Ettrich, Thomas Jens; Keitel, Verena; Graeven, Ullrich; Fischer von Weikersthal, Ludwig; Kolov, Alexander; Edelmann, Thomas; Stein, Alexander; Trarbach, Tanja; Junge, Sabine; Pauligk, Claudia; Virchow, Isabel; Siveke, Jens; Al-Batran, Salah-Eddin; Schuler, Martin

RAMucirumab in combination with TAS102 versus TAS102 monotherapy in metastatic colorectal cancer : Safety results from the phase IIb part of the RAMTAS phase II/III trial of the German AIO (AIO-KRK-0316)

In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 3566 - 3566

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Gauler, Thomas; Guberina, M.; Pierscianek, D.; Wrede, Karsten; Wiesweg, Marcel; Eberhardt, Wilfried; Schuler, Martin; Stuschke, Martin

Re-Irradiation of cerebral Metastases after prophylactic Brain Skull irradiation in small-cell neuroendocrine Lung Cancer (SCLC)

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 197 (2021) Nr. Suppl. 1, S. 176

ISSN: 1439-099X; 0179-7158
Schuler, Martin; Wolf, J.

Registrational phase 2 trial of sotorasib in KRAS p. G12C mutant NSCLC : first disclosure of the CodeBreaK 100 primary analysis

In: Pneumologie Jg. 75 (2021) Nr. Suppl. 1, 61. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V. Leipzig digital, 02.–05.06.2021, S. S38

ISSN: 0934-8387; 1438-8790

Online Volltext: dx.doi.org/
Reinisch, Mattea; Nusch, Arndt; Decker, Thomas; Hartkopf, Andreas; Heinrich, Bernhard J.; Kurbacher, Christian M.; Fuchs, Roswitha; Tesch, Hans; Krabisch, Petra; Brucker, Sara Y.; Fehm, Tanja; Janni, Wolfgang; Kuemmel, Sherko; Lüftner, Diana; Schneeweiss, Andreas; Schuler, Martin; Voges, Claudia; Schubert, Jörg; Fasching, Peter A.;

Ribecca - a phase 3b, multi-center, open label study for women with estrogen receptor positive, locally advanced or metastatic breast cancer treated with ribociclib (lee011) in combination with letrozole : Final results
San Antonio Breast Cancer Virtual Symposium ; December 8-11, 2020; San Antonio, Texas,

In: Cancer Research Jg. 81 (2021) Nr. 4, Supplement, S. PS10 - 31

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Lauri, F.; Hilser, T.; Hense, Jörg; Ting, S. C.; Kansy, B.; Laue, K.; Gauler, Thomas C.; Stuschke, Martin; Schmid, K. W.; Lang, Stephan; Grünwald, Viktor; Schuler, Martin; Kasper, S.;

Systemic inflammatory response parameters as prognostic markers in patients with recurrent or metastatic head and neck cancer treated with immunotherapy
Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,

In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 58

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Lopez, Juanita S.; Camidge, Ross; Iafolla, Marco; Rottey, Sylvie; Schuler, Martin; Hellmann, Matthew; Balmanoukian, Ani; Dirix, Luc; Gordon, Michael; Sullivan, Ryan; Henick, Brian S.; Drake, Charles; Wong, Kit; LoRusso, Patricia; Ott, Patrick; Fong, Lawrence; Schiza, Aglaia; Yachnin, Jeffery; Ottensmeier, Christian; Braiteh, Fadi; Bendell, Johanna; Leidner, Rom; Fisher, George; Jerusalem, Guy; Molenaar-Kuijsten, Laura; Schmidt, Marcus; Laurie, Scott A.; Aljumaily, Raid; Rittmeyer, Achim; Gort, Eelke; Melero, Ignacio; Mueller, Lars; Sabado, Rachel; Twomey, Patrick; Huang, Jack; Yadav, Manesh; Zhang, Jingbin; Mueller, Felicitas; Derhovanessian, Evelyna; Sahin, Ugur; Türeci, Özlem; Powles, Thomas;

Abstract CT301: A phase Ib study to evaluate RO7198457, an individualized Neoantigen Specific immunoTherapy (iNeST), in combination with atezolizumab in patients with locally advanced or metastatic solid tumors
Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, USA,

In: Cancer Research Jg. 80 (2020) Nr. 16: Supplement, S. CT301

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Yang, J. C-H.; Schuler, Martin; Popat, S.; Miura, S.; Heeke, S.; Passaro, A.; de Marinis, F.; Park, K.; Kim, E. S.;

Afatinib in Asian and non-Asian patients (pts) with EGFR mutation positive (EGFRm+) NSCLC harboring major uncommon mutations
ESMO Asia Virtual Congress 2020 ; 20-22 November 2020,

In: Annals of Oncology Jg. 31 (2020) Nr. Supplement 6, S. S1396

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Yang, J.C-H.; Schuler, Martin; Popat, Sanjay; Miura, S.; Heeke, S.; Passaro, A.; de Marinis, Filippo; Park, K.; Kim, E.S.

Afatinib in Asian and non-Asian patients (pts) with EGFR mutation-positive (EGFRm+) NSCLC harboring uncommon mutations

In: Annals of Oncology Jg. 31 (2020) Nr. Suppl. 4, S. S860 - S861

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Subbiah, Vivek; Hu, Mimi I-Nan; Gainor, Justin F.; Mansfield, Aaron Scott; Alonso, Guzman; Taylor, Matthew H.; Zhu, Viola Weijia; Garrido Lopez, Pilar; Amatu, Alessio; Doebele, Robert C; Cassier, Philippe Alexandre; Keam, Bhumsuk; Schuler, Martin; Zhang, Hui; Clifford, Corinne; Palmer, Michael; Green, Jennifer; Turner, Christopher D.; Curigliano, Giuseppe

Clinical activity of the RET inhibitor pralsetinib (BLU-667) in patients with RET fusion+ solid tumors.

In: Journal of Clinical Oncology (JCO) Jg. 38 (2020) Nr. 15_Suppl., S. 109

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Martens, U.; Reiser, M.; Schirrmacher-Memmel, S.; Sellmann, L.; Decker, T.; Schneeweiss, A.; Schuler, Martin; Bengsch, F.; Vannier, C.; Potthoff, K.; Marschner, N.; Kasenda, B.;

First results from INFINITY - A registry on decision making and clinical impact of biomarker-driven precision oncology in routine clinical practice
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,

In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 251 - 252

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Peuker, C. A.; Yaghobramzi, S.; Grunert, C.; Keilholz, L.; Henning, S.; Schaper, S.; Brucker, S.; Decker, T.; Fasching, P.; Fehm, T.; Janni, W.; Kümmel, Sherko; Schneeweiss, A.; Schuler, Martin; Lüftner, D.; Busse, A.;

Influence of CDK4/6 inhibitors on the peripheral immune response in hormone receptor-positive breast cancer
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,

In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 159

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Kasper, Stefan; Hofheinz, R.D.; Stintzing, S.; Götze, T.O.; Sinn, M.; Dechow, T.; Ettrich, T.J.; Keitel, V.; Graeven, U.; Fischer von Weikersthal, L.; Kolov, A.; Edelmann, T.; Stein, A.; Trarbach, T.; Junge, S.; Pauligk, C.; Virchow, I.; Siveke, Jens; Al-Batran, S-E.; Schuler, Martin

Interim safety analysis of the phase IIb study of ramucirumab in combination with TAS102 vs. TAS102 monotherapy in metastatic colorectal cancer : The RAMTAS trial of the German AIO

In: Annals of Oncology Jg. 31 (2020) Nr. Suppl. 4, S. S427 - S428

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Guberina, Marko; Pöttgen, Christoph; Guberina, Nika; Hautzel, Hubertus; Herrmann, Ken; Theegarten, Dirk; Aigner, Clemens; Plones, Till; Gauler, Thomas; Eberhardt, Wilfried; Schuler, Martin; Karpf-Wissel, Rüdiger; Darwiche, Kaid; Stuschke, Martin;

Lymphknoten-Staging von lokal fortgeschrittenen, nicht kleinzelligen Lungenkarzinomen (NSCLC) : Wert von [18F] FDG-PET/CT und EBUS/TBNA zur Festlegung des Zielvolumens bei definitiver Radiotherapie in kurativer Intention
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. Juni - 28. Juni 2020, Wiesbaden, Germany,

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 196 (2020) Nr. S1: Abstracts DEGRO 2020, S. S143

ISSN: 1439-099X; 0179-7158

Online Volltext: dx.doi.org/ (Open Access)
Pöttgen, Christoph; Plajer, D.; Gauler, Thomas; Guberina, Marko; Santiago, Alina; Guberina, Nika; Eberhardt, Wilfried; Schuler, Martin; Darwiche, Kaid; Plönes, Till; Aigner, Clemens; Stuschke, Martin;

Optimierung prognostischer Modelle für das Überleben von Patienten mit lokal fortgeschrittenen kleinzelligen Lungenkarzinomen nach definitiver Radiochemotherapie mittels künstlicher Intelligenz
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. Juni - 28. Juni 2020, Wiesbaden, Germany,

In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 196 (2020) Nr. S1: Abstracts DEGRO 2020, S. S57 - S58

ISSN: 1439-099X; 0179-7158

Online Volltext: dx.doi.org/ (Open Access)
Röhrig, T.; Oechsel, K.; Schuler, U.; Rosenbruch, J.; Neukirchen, M.; Hense, Jörg; Weber, M.; Nauck, F.; Junghanß, C.; Kramer, T.; Oorschot, B. van; Ostgathe, C.; Thuss-Patience, P.; Schweda, Adam; Ullrich, A.; Teufel, Martin; Schuler, Martin; Tewes, Mitra;

Palliative knowledge and self-efficacy expectation of residents before and after palliative care unit rotation - A national study project
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,

In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 210

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Kraskowski, O.; Eberhardt, Wilfried; Metzenmacher, Martin; Zaun, Gregor; McCutcheon, A.; Schmid, Kurt Werner; Schildhaus, Hans-Ulrich; Darwiche, Kaid; Aigner, Clemens; Kasper, Stefan; Hense, Jörg; Gruenwald, Viktor; Wiesweg, Marcel; Schuler, Martin; Pogorzelski, Michael;

Patients with metastatic EGFR-mutated non-small cell lung cancer (NSCLC) show highly favorable outcomes with treatment sequences provided at a comprehensive cancer center
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,

In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 137

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Janku, Filip; Elez, Elena; Iyer, Gopa; Yamamoto, Noboru; Tan, Daniel Shao-Weng; Stathis, Anastasios; Stammberger, Uz M.; Evans, Helen; Seroutou, Abdelkader; Mais, Anna; Schuler, Martin

Phase I dose-finding study of oral ERK1/2 inhibitor LTT462 in patients (pts) with advanced solid tumors harboring MAPK pathway alterations

In: Journal of Clinical Oncology (JCO) Jg. 38 (2020) Nr. 15_Suppl., S. 3640

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schuler, Martin; Tabernero, J.; Massard, C.; Iyer, G. Vasudeva; Witt, Olaf; Doi, T.; Qin, S.; Lu-Emerson, C.; Hargrave, D.; Garcia-Corbacho, J.; Little, S.; Xia, Q.; Santiago-Walker, A.; Moy, C.H.; Hammond, C.; Lau, Y.Y.; Sweiti, H.; Pant, S.

Phase II, open-label study of erdafitinib in adult and adolescent patients (pts) with advanced solid tumours harboring fibroblast growth factor receptor (FGFR) gene alterations

In: Annals of Oncology Jg. 31 (2020) Nr. Suppl. 4, S. 502 - S503

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Hartkopf, Andreas; Nusch, Arnd; Decker, Thomas; Reinisch, Mattea; Heinrich, Bernhard J; Kurbacher, Christian; Fuchs, Roswitha; Tesch, Hans; Krabisch, Petra; Brucker, Sara; Fehm, Tanja N; Janni, Wolfgang; Kümmel, Sherko; Lüftner, Diana; Schneeweiss, Andreas; Schuler, Martin; Voges, Claudia; Schubert, Jörg; Fasching, Peter A

RIBECCA - A phase IIIb, multi-center, open label study for women with estrogen receptor positive locally advanced or metastatic breast cancer treated with ribociclib (LEE011) in combination with letrozole : Results of the third interim analysis

In: Cancer Research Jg. 80 (2020) Nr. 4,

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Thomas, M.; Griesinger, F.; Schuler, Martin; Gainor, J. F.; Curigliano, G.; Kim, D.-W.; Lee, D. H.; Besse, B.; Baik, C. S.; Doebele, R. C.; Cassier, P.; Lopes, G.; Tan, D. S.-W.; Garralda, E.; Paz-Ares, L.; Chul Cho, B.; Gadgeel, S. M.; Liu, S. V.; Turner, C. D.; Subbiah, V.;

Registrational dataset from the phase 1/2 ARROW trial of pralsetinib (BLU-667) in patients (pts) with advanced RET fusion plus non-small-cell lung cancer (NSCLC)
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,

In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 141 - 142

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Hu, M.; Subbiah, V.; Wirth, L.J.; Schuler, Martin; Mansfield, A.S.; Brose, M.S.; Curigliano, G.; Leboulleux, S.; Zhu, Viola W.; Keam, Bhumsuk; Matos, I.; Lin, C-C.; Adkins, Douglas R.; Baik, C.S.; Lopes, G.; Godbert, Y.; Sarker, Debashis; Zhang, H.; Turner, C.; Taylor, M.

Results from the registrational phase I/II ARROW trial of pralsetinib (BLU-667) in patients (pts) with advanced RET mutation-positive medullary thyroid cancer (RET+ MTC)

In: Annals of Oncology Jg. 31 (2020) Nr. Suppl. 4, S. S1084

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Keam, B.; Hu, M. I.; Subbiah, V.; Wirth, L.; Schuler, Martin; Mansfield, A. S.; Brose, M. S.; Curigliano, G.; Leboulleux, S.; Zhu, V. W.; Matos, I.; Adkins, D.; Baik, C. S.; Lopes, G.; Godbert, Y.; Sarker, D.; Zhang, H.; Turner, C. D.; Taylor, M. H.; Lin, C.-C.;

Results from the registrational phase I/II ARROW trial of pralsetinib (BLU-667) in patients (pts) with advanced RET mutation-positive medullary thyroid cancer (RET+ MTC)
ESMO Asia Virtual Congress 2020 ; 20-22 November 2020,

In: Annals of Oncology Jg. 31 (2020) Nr. Supplement 6, S. S1413 - S1414

ISSN: 1569-8041; 0923-7534

Online Volltext: dx.doi.org/ (Open Access)
Darwiche, Kaid; Theegarten, Dirk; Schildhaus, Hans-Ulrich; Schuler, Martin; Wiesweg, Marcel; Aigner, Clemens; Karpf-Wissel, Rüdiger

The impact of needle choice on molecular analysis of ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in NSCLC

In: European Respiratory Journal (ERJ) Jg. 56 (2020) Nr. Suppl. 64,

ISSN: 0903-1936; 1399-3003

Online Volltext: dx.doi.org/
Stockhammer, P.; Ho, C.S.L.; Bankfalvi, Agnes; Plönes, T.; Hegedus, L.; Schuler, Martin; Aigner, Clemens; Schramm, Alexander; Hegedus, B.

A Novel Patient Derived Synchronous Cell Pair with Different Mutations in an ALK-Rearranged Lung Adenocarcinoma Underlines Tumor Heterogeneity

In: Journal of Thoracic Oncology Jg. 14 (2019) Nr. 10, Supplement, S. S571 - S572

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Kasper, Stefan; zur Hausen, Gerrit; Stein, Alexander; Stintzing, Sebastian; Berger, Andreas; Loges, Sonja; Hofheinz, Ralf; Trarbach, Tanja; Graeven, Ullrich; Fischer von Weikersthal, Ludwig; Goetze, Thorsten Oliver; Hagen, Volker A.; Burock, Susen; Hoffmeister, Albrecht; Dechow, Tobias Nicolaas; Pauligk, Claudia; Virchow, Isabel; Siveke, Jens; Al-Batran, Salah-Eddin; Schuler, Martin

A phase IIb study of ramucirumab in combination with TAS102 versus TAS102 monotherapy in metastatic, chemotherapy refractory colorectal cancer patients : The RAMTAS trial of the German AIO (KRK-0316)

In: Journal of Clinical Oncology Jg. 37 (2019) Nr. 15, S. TPS3617 - TPS3617

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Zaatar, M.; Stork, T.; Fangmann, L.; Martens, A.; Collaud, S.; Mardanzai, K.; Plönes, T.; Valdivia, D.; Schuler, Martin; Stuschke, Martin; Darwiche, Kaid; Hegedus, B.; Aigner, Clemens

Advanced Age and High Modiﬁed Glasgow Prognostic Score Are Associated with Increased Complications After Pneumonectomy

In: Journal of Thoracic Oncology Jg. 14 (2019) Nr. 10, Supplement, S. S677

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Tewes, Mitra; Goette, M.; Frikkel, J.; Guyot, M.; Kasper, S.; Metzenmacher, M.; Hense, Jörg; Teufel, Martin; Schuler, Martin; Beckmann, M.;

Barriers and motivation of physical activitiy (PA) in patients with cancer related fatigue (CRF)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin,

In: Oncology Research and Treatment Jg. 42 (2019) Nr. Suppl 4, S. 165

ISSN: 2296-5270; 0378-584X; 1423-0240; 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
Michels, Sebastian Yves Friedrich; Nogova, Lucia; Deschler-Baier, Barbara; Felip, Enriqueta; Rodriguez-Abreu, Delvys; Rosell, Rafael; Sebastian, Martin; Schuler, Martin; Wermke, Martin; Fischer, Rieke Nila; Koleczko, Sophia; Abdulla, Diana S.Y.; Riedel, Richard; Scheffler, Matthias; Fassunke, Jana; Hellmich, Martin; Merkelbach-Bruse, Sabine; Buettner, Reinhard; Wolf, Juergen

EATON: An open-label, multicenter, phase I dose-escalation trial of nazartinib (EGF816) and trametinib in patients with EGFR-mutant non-small cell lung cancer – preliminary data on safety and tolerability

In: Journal of Clinical Oncology Jg. 37 (2019) Nr. 15, S. e20577 - e20577

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Joerger, Markus; Cho, Byoung Chul; Mach, Nicolas; Caballero, Cristina; Soo, Ross A.; Wirth, Manfred; Sayehli, Cyrus; Navarro, Alejandro; Keam, Bhumsuk; Piciu, Ana-Maria; Bender, Sebastian; Nogai, Hendrik; Ellinghaus, Peter; Schuler, Martin

Early clinical experience with the pan-FGFR inhibitor rogaratinib in patients with non-small cell lung cancer selected based on FGFR mRNA expression levels

In: Journal of Clinical Oncology Jg. 37 (2019) Nr. 15, S. e20661 - e20661

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Schuler, Martin;

Integration of immune checkpoint inhibitors in the treatment of early stage lung cancer
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin,

In: Oncology Research and Treatment Jg. 42 (2019) Nr. Suppl 4, S. 13

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/ (Open Access)
Nothdurft, S.; Breitenbücher, Frank; Okimoto, R.; Bivona, T.; Grüner, Barbara M.; Hoelzel, M.; Forster, J.; Kalmbach, S.; Schramm, Alexander; Schuler, Martin

MA17.07 Identification of AHR as a Novel Regulator of Lung Cancer Metastasis

In: Journal of Thoracic Oncology Jg. 14 (2019) Nr. 10, Supplement, S. S319

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
O'Byrne, K.; Yang, J.C.; Wu, Y.; Hirsh, V.; Yamamoto, N.; Popat, S.; Tamiya, A.; Märten, A.; Schuler, Martin

P2.14-60 Afatinib in EGFR Mutation-Positive NSCLC : Activity in Patients with Brain Metastases, and Impact on CNS Progression/Spread

In: Journal of Thoracic Oncology Jg. 14 (2019) Nr. 10, S. 855

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Guberina, M.; Stuschke, Martin; Eberhardt, Wilfried; Gauler, Thomas; Aigner, Clemens; Schuler, Martin; Stamatis, Georgios; Dirk, T.; Jentzen, Walter; Herrmann, Ken; Pöttgen, Christoph;

Prognostic Value of Metabolic Tumor Volume after Induction Chemotherapy in Stage IIIA/B Non-Small-Cell Lung Cancer : Secondary Analysis of a Randomized Phase 3 Trial
61st Annual Meeting of the American Society for Radiation Oncology ; September 15-18, 2019, Chicago, IL, USA,

In: International Journal of Radiation Oncology, Biology, Physics Jg. 105 (2019) Nr. 1, Supplement, S. S146 - S147

ISSN: 1879-355X; 0360-3016

Online Volltext: dx.doi.org/ (Open Access)
Nusch, Arnd; Decker, Thomas; Reinisch, Mattea; Hartkopf, Andreas D.; Heinrich, Bernhard; Kurbacher, Christian M.; Fuchs, Roswitha Dorothea; Tesch, Hans; Krabisch, Petra; Brucker, Sara; Fehm, Tanja N.; Janni, Wolfgang; Kümmel, Sherko; Luftner, Diana; Schneeweiss, Andreas; Schuler, Martin; Voges, Claudia; Schubert, Joerg; Fasching, Peter A.

RIBECCA: A phase IIIb, multicenter, open label study for women with estrogen receptor-positive locally advanced or metastatic breast cancer treated with ribociclib (LEE011) in combination with letrozole—Results of the second interim analysis.

In: Journal of Clinical Oncology Jg. 37 (2019) Nr. 15, S. 1061 - 1061

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Sebastian, M.; Schuler, Martin; Schulz, C.; Deschler-Baier, B.; Kimmich, M.; Hilgert-Daute, K.; Griesinger, F.;

Adverse events self-reported by patients with advanced non-small cell lung cancer treated with osimertinib or chemotherapy in the AURA3 trial
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 111

ISSN: 2296-5270; 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
O'Byrne, K.; Yang, JCH; Wu, Y. L.; Hirsh, V.; Yamamoto, N.; Popat, S.; Tamiya, A.; Maerten, A.; Schuler, Martin;

Afatinib for patients with EGFR mutation-positive (EGFRm plus ) NSCLC : Activity in patients with baseline brain metastases and impact on the rate of central nervous system (CNS) progression or spread
COSA's 45th Annual Scientific Meeting, Mesothelioma and Gastro‐Intestinal Cancers: Technology and Genomics, 13–15 November 2018, Perth Australia,

In: Asia-Pacific Journal of Clinical Oncology Jg. 14 (2018) Nr. Suppl. 7, S. 159 - 160

ISSN: 1743-7555; 1743-7563

Online Volltext: dx.doi.org/
O'Byrne, K.; Yang, J. C-H; Wu, Y-L; Hirsh, V.; Yamamoto, N.; Popat, S.; Tamiya, A.; Maerten, A.; Schuler, Martin;

Central Nervous System or Systemic Progression Analysis for EGFR Mutation-Positive NSCLC Patients Receiving Afatinib in LUX-Lung 3, 6, and 7
Konferenz Medical Oncology Group of Australia Incorporated Annual Scientific Meeting, New Directions in Personalised Cancer Therapy; 1–3 August 2018; Adelaide, Australia,

In: Asia-Pacific Journal of Clinical Oncology Jg. 14 (2018) Nr. Supplement 3, S. 69

ISSN: 1743-7555; 1743-7563

Online Volltext: dx.doi.org/
Bogner, Simon; Schmid, Kurt Werner; Metzenmacher, Martin; Hager, Thomas; Herrmann, Ken; Walter, Robert; Hegedues, Balazs; Herold, Thomas; Eberhardt, Wilfried; Reis, Henning; Goetz, Moritz; Mairinger, Fabian Dominik; Wiesweg, Marcel; Darwiche, Kaid; Aigner, Clemens; Schuler, Martin

Development of predictors for PD-1/PD-L1-directed therapy of non-small cell lung cancer (NSCLC) by gene expression profiling of small diagnostic biopsies (DBX)

In: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. 15 Suppl., S. e15121

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Cao, J.; Wiesweg, Marcel; Fuchs, M.; Stein, A.; Karthaus, M.; Lettmaier, S.; Kretzschmar, A.; Draube, A.; Ettrich, T.; Rüssel, J.; Müller, C.; Rafiyan, M.-R.; Borchert, K.; Schuler, Martin; Kasper, Stefan;

Efficacy and safety of Trifluridin/Tipiracil (FTD/TPI) (Lonsurf (R)) in patients with metastatic colorectal cancer (CRC) in clinical-routine use
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 289

ISSN: 2296-5262; 2296-5270

Online Volltext: dx.doi.org/ (Open Access)
Slaski, C.; Kasper, Stefan; Paul, Andreas; Gerken, G.; Schmid, Kurt Werner; Meiler, Johannes; Teckelnborg, K.; Dechene, Alexander; Schumacher, B.; Markus, P.; Schuler, Martin; Virchow, I.;

Evaluation of prognostic markers in patients (pts) with advanced gastric cancer (GC) and adenocarcinoma of the gastroesophageal junction (AEG) treated with systemic chemothearpy (ctx) at the West German Cancer Center
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 67

ISSN: 2296-5270; 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
Exner, J.-P.; Nadjm, S.; Gauler, Thomas; Pöttgen, Christoph; Krebs, B.; Cheufou, D.; Darwiche, Kaid; Metzenmacher, M.; Theegarten, Dirk; Umutlu, Lale; Hoffmann, Andreas-Claudius; Oezkan, F.; Aigner, Clemens; Taube, Christian; Schuler, Martin; Stamatis, Georgios; Stuschke, Martin; Eberhardt, Wilfried;

Long-term Survival (LT-S) and Survivorship Program (SS-P) of Lung Cancer (LC) Patients (Pts) - B : Implications for Follow-up (F-up) and Surveillance (SV)
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 109 - 110

ISSN: 2296-5270; 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
Nadjm, S.; Exner, J. P.; Gauler, Thomas; Pöttgen, Christoph; Darwiche, Kaid; Cheufou, D.; Krebs, B.; Metzenmacher, M.; Oezkan, F.; Rebmann, Vera; Umutlu, Lale; Deuschl, C.; Li, Y.; Lahner, Harald; Christoph, Daniel; Hoiczyk, M.; Witzke, Oliver; Hoffmann, Andreas-Claudius; Aigner, Clemens; Theegarten, Dirk; Taube, Christian; Schuler, Martin; Stamatis, Georgios; Stuschke, Martin; Eberhardt, Wilfried;

Long-term Survival(LTS) and Survivorship Program(SS-P) of Lung Cancer(LC) Patients(Pts). Investigations(Invest) on LT-toxicities(Tox) and late morbidities(Morb)
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 108

ISSN: 2296-5270; 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
Waberer, Lisa; Homann, Nils; Wirtz, Ralph M.; Schmalenberg, Harald; Haag, Georg Martin; Schuler, Martin; Kasper, Stefan; Goetze, Thorsten Oliver; Pauligk, Claudia; Hofheinz, Ralf; Al-Batran, Salah-Eddin

PD-L1 mRNA expression in patients with resectable gastric cancer and adenocarcinoma of the oesophago-gastric junction undergoing perioperative chemotherapy : Results from the FLOT4 phase III trial of the AIO

In: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. Suppl. 15, S. e24277 - e24277

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Reis, Henning; Niedworok, Christian; Wiesweg, Marcel; Schuler, Martin; Rübben, Herbert; Hadaschik, Boris; Schmid, Kurt Werner; Szarvas, Tibor;

Potentially Targetable Molecular Alterations in 70 Cases of Urachal Cancer
Geared to Learn ; USCAP 107th Annual Meeting ; March 17–23, 2018, Vancouver,

In: Modern Pathology Jg. 31 (2018) Nr. Suppl. 2, S. 378

ISSN: 1530-0285; 0893-3952

Online Volltext: dx.doi.org/ (Open Access)
Fasching, Peter A.; Nusch, Arnd; Heinrich, Bernhard; Brucker, Sara; Decker, Thomas; Kurbacher, Christian M.; Tesch, Hans; Krabisch, Petra; Mundhenke, Christoph; Fehm, Tanja N.; Janni, Wolfgang; Lueftner, Diana; Schneeweiss, Andreas; Schuler, Martin; Guderian, Gernot; Voges, Claudia; Schubert, Joerg; Kummel, Sherko

RIBECCA: A phase IIIb, multi-center, open label study for women with estrogen receptor positive locally advanced or metastatic breast cancer treated with ribociclib (LEE011) in combination with letrozole : Results of the first interim analysis

In: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. Suppl. 15, S. 1051

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Joerger, Markus; Cassier, Philippe Alexandre; Penel, Nicolas; Cathomas, Richard; Richly, Heike; Schostak, Martin; Janitzky, Andreas; Wermke, Martin; Nogova, Lucia; Tai, David Wai-Meng; Sayehli, Cyrus; Grüllich, Carsten; Grande, Enrique; Navarro, Alejandro; Park, Se Hoon; Nogai, Hendrik; Bender, Sebastian; Ellinghaus, Peter; Schuler, Martin

Rogaratinib in patients with advanced urothelial carcinomas prescreened for tumor FGFR mRNA expression and effects of mutations in the FGFR signaling pathway

In: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. Suppl. 15, S. 4513 - 4513

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Cassier, P.; Penel, N.; Cathomas, R.; Richly, Heike; Schostak, M.; Janitzky, A.; Wermke, M.; Nogova, L.; Tai, D.; Sayehli, C.; Grüllich, C.; Grande, E.; Navarro, A.; Park, S. H.; Nogai, H.; Bender, S.; Ellinghaus, P.; Joerger, M.;

Rogaratinib in patients with advanced urothelial carcinomas selected for tumor FGFR mRNA expression and impact of mutations in the FGFR signaling pathway
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; Wien, 28. September - 2. Oktober 2018,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 321

ISSN: 2296-5270; 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
Sayehli, Cyrus; Nogova, Lucia; Nogai, Hendrik; Park, Se Hoon; Richly, Heike; Cathomas, Richard; Wermke, Martin; Bender, Sebastian; Navarro, Alejandra; Schostak, Martin; Grande, Enrique; Cassier, Philippe; Janitzky, Andreas; Penel, Nicolas; Ellinghaus, Peter; Tai, David Wai-Meng; Gillessen, Silke; Grüllich, Carsten; Joerger, Markus; Schuler, Martin

Rogaratinib treatment of patients with advanced urothelial carcinomas prescreened for tumor FGFR mRNA expression.

In: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. 6 Suppl., S. 494

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/ (Open Access)
Wiesweg, Marcel; Reis, Henning; Köster, T.; Goetz, M.; Worm, K.; Herold, T.; Paul, Andreas; Dechene, Alexander; Schumacher, B.; Markus, P.; Virchow, I.; Kostbade, K.; Wolf, N.; Zaun, G.; Metzenmacher, M.; Schmid, Kurt Werner; Schuler, Martin; Kasper, Stefan;

Signaling network activation in colorectal cancer : p70S6K phosphorylation as a prognostic marker
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 55

ISSN: 2296-5270; 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
Stein, G.; Stelmach, Patrick; Kasper, Stefan; Paul, Andreas; Wedemeyer, Heiner H.; Schmid, Kurt Werner; Schumacher, B.; Markus, P.; Siffert, Winfried; Schuler, Martin; Bachmann, Hagen Sjard; Virchow, I.;

The prognostic impact of UDP-glucuronyltransferase 1A1*1 (UGT1A1*1) polymorphism in patients with advanced colorectal and non-colorectal cancer treated with irinotecan-based systemic chemotherapies
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,

In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 122 - 123

ISSN: 2296-5262; 2296-5270

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Nogova, L.; Heidenreich, A.; Tai, D.; Cassier, P.; Richly, Heike; Cho, B. C.; Sayehli, C. M.; Navarro, A.; Bender, Stefan; Ocker, M.; Nogai, H.; Wagner, A.; Ince, S.; Ellinghaus, P.; Joerger, M.

Anti-tumor activity of the pan-FGFR inhibitor rogaratinib in patients with advanced urothelial carcinomas selected based on tumor FGFR mRNA expression levels

In: Annals of Oncology Jg. 28 (2017) Nr. Suppl. 5,

ISSN: 0923-7534; 1569-8041
Sahin, U.; Schuler, Martin; Bauer, Sebastian; Krilova, A.; Utsch, M.; Huber, C.; Tureci, O.

First-in-human study of IMAB362, an anti-claudin 18.2 monoclonal antibody, in patients with advanced gastroesophageal cancer

In: Annals of Oncology Jg. 28 (2017) Nr. Suppl. 5,

ISSN: 0923-7534; 1569-8041
Schuler, Martin

Liquid Biopsies for Dynamic Monitoring of EGFR Mutations in Lung Cancer

In: Journal of Thoracic Oncology Jg. 12 (2017) Nr. 1, Suppl., S. 85

ISSN: 1556-1380; 1556-0864
Hamacher, R.; Kampfe, D.; Ahrens, M.; Reuter-Jessen, K.; Schuler, Martin; Schildhaus, H. U.; Bauer, Sebastian

PD-L1 inhibition - a new therapeutic opportunity in cutaneous angiosarcoma?

In: Annals of Oncology Jg. 28 (2017) Nr. Suppl. 5,

ISSN: 0923-7534; 1569-8041
Lückerath, M.; Kasper, Stefan; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Meiler, Johannes; Wiesweg, M.; Neuhaus, I.; Dechene, Alexander; Mende, B.; Schumacher, B.; Markus, P.; Schuler, Martin; Virchow, I.;

Evaluation of prognostic markers in patients (pts) with metastatic colorectal cancer (mCRC) treated with a bevacizumab (bev) based chemotherapy (ctx) at the West German Cancer Center
Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin,

In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 77

ISSN: 2296-5270; 2296-5262; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/
Pogorzelski, M.; Hilser, T.; Ting, Saskia; Vossebein, I.; Gauler, Thomas; Abendroth, A.; Lang, Stephan; Stuck, Boris; Abu-Jawad, J.; Stuschke, Martin; Schmid, Kurt Werner; Schuler, Martin; Kasper, Stefan

Evaluation of systemic inflammatory response (SIR) markers in recurrent or metastatic head and neck squamous cell carcinoma (r/m HNSCC)

In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 307 - 308

ISSN: 2296-5270

Online Volltext: dx.doi.org/
Abendroth, A.; Markus, M.; Abramczyk, M.; Noureddine, R.; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Markus, P.; Schumacher, B.; Meiler, Johannes; Wiesweg, M.; Kaiser, Gernot Maximil; Dechene, Alexander; Trarbach, Tanja; Schuler, Martin; Kasper, Stefan;

Evaluation of systemic inflammatory response (SIR) markers in advanced biliary tract cancer (ABTC)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,

In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 5 - 6

ISSN: 2296-5270; 0378-584X; 2296-5262; 1423-0240

Online Volltext: dx.doi.org/
Markus, M.; Kasper, Stefan; Noureddine, R.; Abramczyk, M.; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Markus, P.; Schumacher, B.; Meiler, Johannes; Wiesweg, M.; Kaiser, Gernot Maximil; Dechene, Alexander; Trarbach, Tanja; Schuler, Martin; Abendroth, A.

Evaluation of systemic inflammatory response (SIR) markers in pancreatic ductal adenocarcinoma (PDAC)

In: Oncology Research and Treatment Jg. 38 (2015) Nr. S 5, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz, S. 4 - 5

ISSN: 2296-5270; 0378-584X; 1423-0240; 2296-5262

Online Volltext: dx.doi.org/
Thomas, M.; Schuler, Martin; Potzner, M.; Szczudlo, T.; Sutradhar, S.; Yovine, A.; Wolf, J.;

Experience from the ASCEND-1 trial : Ceritinib in patients (Pts) with ALK-rearranged (ALK plus ) Non-Small Cell Lung Cancer (NSCLC) and brain metastases
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,

In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 270

ISSN: 2296-5270; 0378-584X; 1423-0240; 2296-5262

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Stuschke, Martin; Gauler, Thomas; Welter, Stefan; Schuler, Martin; Stamatis, Georgios; Eberhardt, Wilfried;

Hirnmetastasen bei Patienten mit lokal fortgeschrittenem NSCLC nach multimodaler kurativer Therapie in einem randomisierten Protokoll : prognostische Faktoren
21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,

In: Strahlentherapie und Onkologie Jg. 191 (2015) Nr. Suppl. 1, S. 36 - 37

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/
Falkenhorst, J.; Treckmann, Jürgen-Walter; Nguyen, B. P.; Podleska, Lars; Reis, A. C.; Virchow, I.; Schuler, Martin; Bauer, Sebastian;

Longitudinal analysis of the impact of the introduction of tyrosine kinase inhibitor therapy on overall survival of patients with gastrointestinal stromal tumors treated at the West German Cancer Center
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,

In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 167 - 167

ISSN: 2296-5270; 0378-584X; 1423-0240; 2296-5262

Online Volltext: dx.doi.org/
Abendroth, A.; Noureddine, R.; Abramczyk, M.; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Markus, P.; Meiler, Johannes; Wiesweg, M.; Dechene, Alexander; Schumacher, B.; Kaiser, Gernot Maximil; Schuler, Martin; Kasper, Stefan;

Prognostische Faktoren bei Patienten mit fortgeschrittenen Pankreaskarzinomen, die am Westdeutschen Tumorzentrum (WTZ) sequentielle Chemotherapien erhalten haben.
121. Kongress der Deutschen Gesellschaft für Innere Medizin e.V. 18. - 21. April 2015, Mannheim,

In: Der Internist Jg. 56 (2015) Nr. S1, S. 38 - 39

ISSN: 0020-9554; 1432-1289

Online Volltext: dx.doi.org/
Abendroth, A.; Abramczyk, M.; Noureddine, R.; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Baba, Hideo Andreas; Meiler, Johannes; Wiesweg, M.; Kaiser, Gernot Maximil; Bockisch, Andreas; Dechene, Alexander; Forsting, Michael; Schuler, Martin; Kasper, Stefan;

Prognostische Faktoren bei Patienten mit fortgeschrittenen cholangiozellulären Karzinomen, die am Westdeutschen Tumorzentrum (WTZ) sequentielle Chemotherapien erhalten haben
121. Kongress der Deutschen Gesellschaft für Innere Medizin e.V., 18. - 21. April 2015, Mannheim,

In: Der Internist Jg. 56 (2015) Nr. S 1, S. 37

ISSN: 1432-1289

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Graupner, B.; Theegarten, Dirk; Gauler, Thomas; Jendrossek, Verena; Freitag, Lutz; Abu Jawad, Jehad; Gkika, E.; Wohlschläger, Jeremias; Welter, Stefan; Hoiczyk, M.; Schuler, Martin; Stamatis, Georgios; Eberhardt, Wilfried; Stuschke, Martin;

Rekursive Partitions-Analyse prognostischer Faktoren für das Langzeit-Überleben nach trimodaler Therapie von Patienten mit lokal fortgeschrittenem NSCLC
21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,

In: Strahlentherapie und Onkologie Jg. 191 (2015) Nr. Suppl. 1, S. 23

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/
Virchow, I.; Podleska, Lars; Pöttgen, Christoph; Reis, A. C.; Steinau, H. U.; Täger, Georg; Farzaliyev, F.; Schuler, Martin; Bauer, Sebastian;

Solitary fibrous tumors/haemangiopericytoma : Analysis of prognostic factors of 28 patients from a high volume sarcoma center
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,

In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 246

ISSN: 2296-5270; 0378-584X; 1423-0240; 2296-5262

Online Volltext: dx.doi.org/
Mertins, S.; Virchow, I.; Farzaliyev, F.; Geismar, Dirk; Podleska, Lars; Pöttgen, Christoph; Reis, A. C.; Steinau, H. U.; Stuschke, Martin; Täger, Georg; Treckmann, Jürgen-Walter; Schuler, Martin; Bauer, Sebastian;

TNM-classification for clear cell sarcomas - is it useful?
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,

In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 247 - 248

ISSN: 2296-5270; 0378-584X; 1423-0240; 2296-5262

Online Volltext: dx.doi.org/
Kasper, Stefan; Meiler, Johannes; Knipp, Heike; Hohler, T.; Reimer, P.; Steinmetz, T.; Berger, W.; Linden, G.; Ting, Saskia; Markus, P.; Paul, Andreas; Dechene, Alexander; Kostbade, K.; Schuler, Martin; Trarbach, Tanja;

Cetuximab biweekly plus mFOLFOX6 as first-line therapy in patients (pts) with KRAS wild-type (wt) metastatic colorectal cancer (mCRC) - Primary endpoint analysis of the CEBIFOX trial
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 99 - 100

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Köhler, Johannes; Schuler, Martin; Gauler, Thomas; Nopel-Dunnebacke, S.; Hoffmann, Andreas-Claudius; Kasper, Stefan; Nensa, Felix; Gomez, Benedikt; Hahnemann, M.; Breitenbücher, Frank; Cheufou, D.; Ozkan, F.; Darwiche, Kaid; Hoiczyk, M.; Welter, Stefan; Eberhardt, Wilfried; Teschler, Helmut; Stamatis, Georgios; Hahn, S. A.; Baraniskin, A.;

Circulating U2 small nuclear RNA fragments as a diagnostic and prognostic biomarker in lung cancer patients
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 226 - 227

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Gauler, Thomas; Nel, I.; Bublitz, K.; Lazaridis, L.; Schuler, Martin; Hoffmann, Andreas-Claudius;

Circulating tumor cell composition and molecular markers in metastasized renal cell carcinoma (mRCC)
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 131

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Jehn, U.; Nel, I.; Schuler, Martin; Gauler, Thomas; Hoffmann, Andreas-Claudius;

Circulating tumor cell subgroups and outcome in patients with non-small-cell-lung-cancer receiving platinum based treatment
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 89

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Thomas, M.; Wolf, J.; Schuler, Martin; Goldwasser, M.; Boral, A.; Shaw, A. T.;

Clinical activity of the ALK inhibitor LDK378 in advanced, ALK-positive NSCLC
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 89 - 90

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Stuschke, Martin; Pöttgen, Christoph; Gauler, Thomas; Friedel, G.; Veit, S.; Heinrich, V.; Welter, Stefan; Spengler, W.; Schmidberger, H.; Lutke-Brintrup, D.; Lehmann, Nils; Jöckel, Karl-Heinz; Schuler, Martin; Stamatis, Georgios; Eberhardt, Wilfried;

Definitive Hyperfractionated Accelerated (AHF) Radiochemotherapy (CRT) Versus Neoadjuvant AHF-CRT and Surgery (S) for Patients (pts) With Operable Stage IIIA(N2)/Selected IIIB Non-small-Cell Lung Cancer (NSCLC) Following Induction Chemotherapy (IND-C) : Results From a Multicenter Phase III Study
56th Annual Meeting of the American Society for Radiation Oncology ; 14-17 September 2014, San Francisco, CA, USA,

In: International Journal of Radiation Oncology, Biology, Physics Jg. 90 (2014) Nr. 1, Supplement, S. S146 - S147

ISSN: 1879-355X; 0360-3016

Online Volltext: dx.doi.org/
Stuschke, Martin; Pöttgen, Christoph; Gauler, Thomas; Friedel, G.; Veit, S.; Heinrich, V.; Gkika, E.; Hepp, R.; Welter, Stefan; Spengler, W.; Schmidberger, H.; Lutke-Brintrup, D.; Lehmann, Nils; Jöckel, Karl-Heinz; Schuler, Martin; Stamatis, Georgios; Eberhardt, Wilfried;

Definitive accelerated-hyperfractionated (AHF) Chemoradiotherapy (CRT) vs. neoadjuvant AHF-CRT and Surgery (S) for Patients with operable NSCLC in Stage IIIA(N2)/IIIB after Induction Chemotherapy (IND-C) : Results of a randomized Multicentre Study
20. Jahreskongress der Deutschen Gesellschaft für Radioonkologie (DEGRO), 3. bis 6. Juli 2014, Düsseldorf,

In: Strahlentherapie und Onkologie Jg. 190 (2014) Nr. Suppl. 1, S. 5 - 6

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/
Kim, D.; Mehra, R.; Tan, DSW; Felip, E.; Chow, LQM; Camidge, D. R.; Vansteenkiste, J.; Sharma, S.; De Pas, T.; Riely, G. J.; Solomon, B. J.; Wolf, J.; Thomas, M.; Schuler, Martin; Liu, G.; Santoro, A.; Geraldes, M.; Boral, A. L.; Yovine, A.; Shaw, A. T.;

Efficacy and Safety of Ceritinib in Patients With Advanced Anaplastic Lymphoma Kinase (ALK)-Rearranged (ALK plus ) Non-Small Cell Lung Cancer (NSCLC) : An Update of ASCEND-1: Metastatic Non-Small Cell Lung Cancer
2014 Chicago Multidisciplinary Symposium in Thoracic Oncology ; 30 October-1 November 2014, Chicago, Illinois, USA,

In: International Journal of Radiation Oncology, Biology, Physics Jg. 90 (2014) Nr. 5, Supplement, S. S33 - S34

ISSN: 1879-355X; 0360-3016

Online Volltext: dx.doi.org/
Wu, Y.; Geater, S. L.; Mok, T.; OByrne, K. J.; Schuler, Martin; Sequist, L. V.; Yang, J. C.; Massey, D.; OBrien, D.; Zazulina, V.;

Epidermal Growth Factor Receptor (EGFR)-Mediated Adverse Events (AEs) in Patients (pts) With EGFR-Mutation Positive (EGFR M+) Non-Small Cell Lung Cancer (NSCLC) Treated With Afatinib (A) : Metastatic Non-Small Cell Lung Cancer
2014 Chicago Multidisciplinary Symposium in Thoracic Oncology ; 30 October-1 November 2014, Chicago, Illinois, USA,

In: International Journal of Radiation Oncology, Biology, Physics Jg. 90 (2014) Nr. 5, Supplement, S. S41

ISSN: 1879-355X; 0360-3016

Online Volltext: dx.doi.org/
Gauler, Thomas; Pogorzelski, M.; Ting, Saskia; Breitenbücher, Frank; Vossebein, I.; Hoffarth, S.; Lang, Stephan; Bergmann, Christoph; Abu Jawad, Jehad; Markowetz, J.; Schmid, Kurt Werner; Schuler, Martin; Kasper, Stefan;

Impact of human papilloma virus infection on the response of head and neck cancers (HNSCC) to anti-epidermal growth factor receptor (EGFR) antibody therapy
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 76

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Kasper, Stefan; Ting, Saskia; Meiler, Johannes; Knipp, Heike; Hohler, T.; Reimer, P.; Steinmetz, T.; Berger, W.; Linden, G.; Worm, K.; Schmid, Kurt Werner; Markus, P.; Paul, Andreas; Dechene, Alexander; Forsting, Michael; Kostbade, K.; Trarbach, Tanja; Schuler, Martin;

Molecular and clinical predictors of the efficacy of cetuximab in combination with mFOLFOX6 in 1st line treatment of patients (pts) with metastatic colorectal cancer (mCRC) – subgroup analyses of the CEBIFOX trial
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 100 - 101

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Kasper, Stefan; Abendroth, A.; Abramczyk, M.; Noureddine, R.; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Markus, P.; Meiler, Johannes; Wiesweg, M.; Kaiser, Gernot Maximil; Dechene, Alexander; Schuler, Martin;

Outcome of patients (pts) with advanced pancreaticobiliary cancers treated with sequential chemotherapies at the West German Cancer Center (WTZ)
Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 51

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Sequist, L.; Wu, Y.; Schuler, Martin; OByrne, K.; Sebastian, M.; Popat, S.; Boyer, M.; Mok, T.; Yamamoto, N.; Hirsh, V.; Geater, S. L.; Zhou, C.; Massey, D.; Zazulina, V.; Jones, H.; Yang, J.;

Overall Survival (OS) With Afatinib Versus Chemotherapy in Patients (Pts) With Advanced Non-Small Cell Lung Cancer (NSCLC) Harboring Common (Del19/L858R) Epidermal Growth Factor Receptor Mutations (EGFR Mut) : Results of LUX-Lung 3 (LL3) and LUX-Lung 6 (LL6): Metastatic Non-Small Cell Lung Cancer
2014 Chicago Multidisciplinary Symposium in Thoracic Oncology ; 30 October-1 November 2014, Chicago, Illinois, USA,

In: International Journal of Radiation Oncology, Biology, Physics Jg. 90 (2014) Nr. 5, Supplement, S. S5 - S6

ISSN: 1879-355X; 0360-3016

Online Volltext: dx.doi.org/
Welt, Anja; Kasper, Stefan; Tewes, Mitra; Aktas, B.; Hoffmann, Oliver; Wiesweg, M.; Ting, Saskia; Reis, Henning; Worm, K.; Richly, Heike; Hense, Jörg; Palmer, M. R.; Lee, B. H.; Wendling, J.; Kossow, J.; Scheulen, Max Ernst; Lehnerdt, C.; Kohl, M.; Derks, C.; Slottky, S.; Haus, U.; Schmid, Kurt Werner; Kimmig, Rainer; Schuler, Martin

Preemptive tumor profiling for biomarker-stratified early clinical drug development in metastatic breast cancer patients

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1: 31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie Berlin, 19.-22. Februar 2014: Abstracts, S. 19

ISSN: 2296-5262

Online Volltext: dx.doi.org/ (Open Access)
Abendroth, A.; Abramczyk, M.; Nourredine, R.; Paul, A.; Gerken, Guido; Schmid, Kurt Werner; Baba, Hideo Andreas; Meiler, Johannes; Wiesweg, M.; Kaiser, Gernot Maximil; Dechene, Alexander; Bockisch, Andreas; Forsting, Michael; Schuler, Martin; Kasper, Stefan;

Prognostic factors in patients (pts) with advanced cholangiocellular carcinoma (CCC) receiving sequential chemotherapies (CTX) at the West German Cancer Center (WTZ)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 122 - 123

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Abendroth, A.; Nourredine, R.; Abramczyk, M.; Paul, A.; Gerken, Guido; Schmid, Kurt Werner; Markus, P.; Meiler, Johannes; Wiesweg, M.; Kaiser, Gernot Maximil; Dechene, Alexander; Schuler, Martin; Kasper, Stefan;

Prognostic factors in patients with pancreatic cancer receiving sequential chemotherapies (CTX) at the West German Cancer Center (WTZ), one of the 12 Oncology Centers of Excellence in Germany
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 123 - 124

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Graupner, B.; Theegarten, Dirk; Gauler, Thomas; Kleinhans, J.; Jendrossek, Verena; Freitag, Lutz; Abu Jawad, Jehad; Gkika, E.; Wohlschläger, Jeremias; Welter, Stefan; Hoiczyk, M.; Schuler, Martin; Stamatis, Georgios; Eberhardt, Wilfried; Stuschke, Martin;

Prognostisches Modell für das Langzeit-Überleben von Patienten mit lokal fortgeschrittenem nicht-kleinzelligen Lungenkarzinom (NSCLC) nach neoadjuvanter Radiochemotherapie (RT/CT) und Resektion
20. Jahreskongress der Deutschen Gesellschaft für Radioonkologie (DEGRO), 3. bis 6. Juli 2014, Düsseldorf,

In: Strahlentherapie und Onkologie Jg. 190 (2014) Nr. Suppl 1, S. 17

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/
Schuler, Martin; Sequist, L. V.; Yang, J. C.; Yamamoto, N.; OByrne, K. J.; Mok, T.; Geater, S. L.; Massey, D.; Wind, S.; OBrien, D.; Lorence, R.; Wu, Y. L.;

Safety profile of afatinib in first-line therapy of patients with metastatic EGFR mutation-positive (M plus ) non-small cell lung cancer (NSCLC) : Comparative analysis of Asian and non-Asian patients from two randomized trials
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 90

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Richly, Heike; Scheulen, Max Ernst; Wiesweg, Marcel; Abendroth, A.; Schuler, Martin; Bauer, Sebastian;

Systemic treatment of metastatic uveal melanoma - a silver lining on the horizon?
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, 31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie Berlin, 19.-22. Februar 2014: Abstracts, S. 118 - 119

ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X

Online Volltext: dx.doi.org/
Nogova, L.; Gardizi, M.; Bos, M.; Scheffler, M.; Papachristou, I.; Wompner, C.; Heukamp, L.; Schildhaus, H. U.; Fuhr, U.; Sos, M.; Eberhardt, Wilfried; Wiesweg, Marcel; Schmid, Kurt Werner; Schuler, Martin; Thomas, R.; Buttner, R.; Wolf, J.;

TRY : A phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small-cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 92

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Nogova, Lucia; Gardizi, Masyar; Bos, Marc Christiaan Allardt; Scheffler, Matthias; Mattonet, Christian; Heukamp, Lukas Carl; Schildhaus, Hans-Ulrich; Fuhr, Uwe; Eberhardt, Wilfried; Reis, Henning; Wiesweg, Marcel; Schmid, Kurt Werner; Schoch, Gernot; Ko, Yon-Dschun; Serke, Monika Heidi; Schuler, Martin H.; Büttner, Reinhard; Wolf, Jürgen

TRY : A phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation

In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15, Suppl., S. 8109

ISSN: 0732-183X; 1527-7755

Online Volltext: dx.doi.org/
Pöttgen, Christoph; Graupner, B.; Theegarten, Dirk; Gauler, Thomas; Freitag, Lutz; Abu Jawad, Jehad; Gkika, E.; Wohlschläger, Jeremias; Welter, Stefan; Hoiczyk, M.; Schuler, Martin; Stamatis, Georgios; Eberhardt, Wilfried; Stuschke, Martin;

Vergleich von pCR und mediastinalem Downstaging als Surrogat- Marker für das Langzeit-Überleben von Patienten mit lokal fortgeschrittenem nicht-kleinzelligen Lungenkarzinom (NSCLC) nach neoadjuvanter Radiochemotherapie (RT/CT) und Resektion (Trimodalität)
20. Jahreskongress der Deutschen Gesellschaft für Radioonkologie (DEGRO), 3. bis 6. Juli 2014, Düsseldorf,

In: Strahlentherapie und Onkologie Jg. 190 (2014) Nr. Suppl. 1, S. 17

ISSN: 0179-7158; 1439-099X

Online Volltext: dx.doi.org/
Wiesweg, Marcel; Ting, Saskia; Reis, Henning; Worm, K.; Kasper, Stefan; Bauer, Sebastian; Gauler, Thomas; Welt, Anja; Richly, Heike; Tewes, Mitra; Meiler, Johannes; Hense, Jörg; Eberhardt, Wilfried; Derks, Christian; Cortes-Incio, D.; Skottky, S.; Wohlschläger, Jeremias; Breitenbucher, F.; Freitag, Lutz; Stamatis, Georgios; Schmid, Kurt Werner; Schuler, Martin;

WTZ-Tumorprofil-A preemptive biomarker profiling program in relation to personalized clinical drug development at a large German Comprehensive Cancer Center : Two years experience
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,

In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 2 - 3

ISSN: 2296-5262

Online Volltext: dx.doi.org/
Yang, J. C.; Sequist, L. V.; Geater, S. L.; Tsai, C. M.; Mok, TSK; Schuler, Martin; Yamamoto, N.; Massey, D.; Zazulina, V.; Wu, Y. L.;

Activity of afatinib in uncommon epidermal growth factor receptor (EGFR) mutations : findings from three trials of afatinib in EGFR mutation-positive lung cancer
15th World Conference on Lung Cancer, October 27 - 30 2013, Sydney, Australia,

In: Journal of Thoracic Oncology Jg. 8 (2013) Nr. Suppl. 2, S. 141

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/
Hoiczyk, M.; Herbrik, M.; Grabellus, Florian; Podleska, Lars; Pöttgen, Christoph; Schuler, Martin; Bauer, Sebastian;

Brain metastases in soft tissue sarcoma patients - incidence, prognosis and outcome
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,

In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 181

ISSN: 0378-584X; 1423-0240

Online Volltext: dx.doi.org/
Sequist, L. V.; Yang, J. C.; Yamamoto, N.; OByrne, K.; Schuler, Martin; Mok, T.; Geater, S. L.; Massey, D.; Wind, S.; OBrien, D.; Lorence, R.; Wu, Y. L.;

Comparative safety profile of afatinib in asian and non-asian patients with EGFR mutation-positive (EGFR M plus) non-small cell lung cancer (NSCLO)
15th World Conference on Lung Cancer, October 27 - 30 2013, Sydney, Australia,

In: Journal of Thoracic Oncology Jg. 8 (2013) Nr. Suppl. 2, S. 1197

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Schuler, Martin; Yang, J. C.; Sequist, L. V.; Hirsh, V.; OByrne, K.; Yamamoto, N.; Massey, D.; Shahidi, M.; Zazulina, V.; Mok, T.;

Effiacy of afatinib vs. chemotherapy in treatment-naive patients with non-small cell lung cancer (NSCLC) harbouring activating EGFR mutations with or without metastatic brain disease
15th World Conference on Lung Cancer, October 27 - 30 2013, Sydney, Australia,

In: Journal of Thoracic Oncology Jg. 8 (2013) Nr. Suppl. 2, S. S299 - S300

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Kasper, Stefan; Breitenbücher, Frank; Markowetz, J.; Reis, Henning; Ting, Saskia; Worm, K.; Meiler, Johannes; Schmid, Kurt Werner; Trarbach, Tanja; Schuler, Martin;

Molecular dissection of effector mechanisms of RAS-induced resistance to monoclonal anti-EGFR antibodies
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,

In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 116 - 117

ISSN: 0378-584X; 1423-0240

Online Volltext: dx.doi.org/
Abendroth, A.; Abramczyk, M.; Paul, Andreas; Gerken, Guido; Schmid, Kurt Werner; Markus, P.; Meiler, Johannes; Tometten, M.; Wiesweg, Marcel; Kaiser, Gernot Maximil; Dechene, Alexander; Trarbach, Tanja; Schuler, Martin; Kasper, Stefan;

Outcome of patients (pts) with advanced pancreaticobiliary cancers treated with sequential chemotherapies at the West German Cancer Center (WTZ), one of the 11 Oncology Centers of Excellence in Germany
17 Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,

In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 263

ISSN: 0378-584X; 1423-0240

Online Volltext: dx.doi.org/
Tewes, Mitra; Kasper, Stefan; Aktas, B.; Hoffmann, A.; Wiesweg, M.; Ting, Saskia; Reis, Henning; Worm, K.; Richly, Heike; Hense, Jörg; Kern, P.; Scheulen, Max Ernst; Skottky, S.; Peters, M.; Schlegel, R.; Lee, B. H.; Palmer, M. R.; Monahan, J. E.; Haus, U.; Schmid, Kurt Werner; Kimmig, Rainer; Schuler, Martin; Welt, Anja;

Preemptive tumor profiling for biomarker-stratified early clinical drug development in metastastic breast cancer patients
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,

In: Oncology Research and Treatment Jg. 36 (2013) Nr. Suppl. 7, S. 157

ISSN: 0378-584X; 1423-0240

Online Volltext: dx.doi.org/
Nel, I.; Gauler, Thomas; Nickel, A.; Eberhardt, Wilfried; Thomale, Jürgen; Schuler, Martin; Hoffmann, A.;

Prä-therapeutische ex-vivo Reparatur Kinetiken von Cisplatin-DNA-Addukten in Zirkulierenden Tumorzellen als Platin-Resistenz Test
119. Kongress der Deutschen Gesellschaft für Innere Medizin e.V., 06. - 09. April 2013, Wiesbaden,

In: Der Internist Jg. 54 (2013) Nr. Suppl. 1, S. 95 - 96

ISSN: 0020-9554

Online Volltext: dx.doi.org/
Nogova, L.; Gardizi, M.; Bos, MCA; Scheffler, M.; Papachristou, I.; Wompner, C.; Heukamp, L. C.; Schildhaus, H. U.; Fuhr, U.; Sos, M. L.; Eberhardt, Wilfried; Wiesweg, Marcel; Schmid, Kurt Werner; Schuler, Martin; Thomas, R. K.; Buttner, R.; Wolf, J.

TRY : A phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small-cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation

In: Onkologie / Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich Jg. 36 (2013) Nr. Suppl. 7, S. 30

ISSN: 0378-584X; 1423-0240

Online Volltext: dx.doi.org/
Mühlenberg, Thomas; Grunewald, S.; Schuler, Martin; Bauer, Sebastian;

Targeting glucose metabolism by 2-Deoxyglucose in Gastrointestinal Stromal Tumors
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,

In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 246

ISSN: 0378-584X; 1423-0240

Online Volltext: dx.doi.org/
Nogova, L.; Bos, M.; Gardizi, M.; Scheffler, M.; Papachristou, I.; Wompner, C.; Heukamp, L. C.; Schildhaus, H.; Fuhr, U.; Sos, M. L.; Eberhardt, Wilfried; Wiesweg, Marcel; Schmid, Kurt Werner; Schuler, Martin; Buttner, R.; Wolf, J.

Try : a phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small-cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation

In: Journal of Thoracic Oncology Jg. 8 (2013) Nr. Suppl. 2, S. S914 - S915

ISSN: 1556-1380; 1556-0864

Online Volltext: dx.doi.org/ (Open Access)
Wolf, Jürgen; LoRusso, Patricia M.; Camidge, Ross D.; Perez, Jose Manuel; Tabernero, Josep; Hidalgo, Manuel; Schuler, Martin; Tian, Gary G.; Soria, Jean Charles; Delord, Jean Pierre; Campone, Mario; Bachelot, Thomas; van der Noll, Ruud; Ringeisen, Francois P.; Nogova, Lucia; Sequist, Lecia V.; Schellens, Jan H. M.

A phase I dose escalation study of NVP-BGJ398, a selective pan FGFR inhibitor in genetically preselected advanced solid tumors

In: Cancer Research Jg. 72 (2012) Nr. 8, Suppl., S. LB - 122

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Christoph, Daniel C.; Asuncion, Bernadette Reyna; Wynes, Murry; Gauler, Thomas C.; Wohlschläger, Jeremias; Theegarten, Dirk; Welter, Stefan; Tran, Cindy; Hassan, Biftu; Loewendick, Heike; Peglow, Anja; Schuler, Martin; Eberhardt, Wilfried; Hirsch, Fred R.

Folylpoly-α-glutamate synthetase and thymidylate synthase are associated with clinical outcome from pemetrexed-based therapy in advanced non-small cell lung cancer (NSCLC)

In: Cancer Research Jg. 72 (2012) Nr. 8, Suppl., S. 1713

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Simon, Susanne; Fererra, Loretta; Galietta, Luis; Grabellus, Florian; Breitenbücher, Frank; Schuler, Martin; Fletcher, Jonathan; Bauer, Sebastian

Functional characterization of DOG1 in Gastrointestinal Stromal Tumors (GIST)

In: Cancer Research Jg. 72 (2012) Nr. 8, Suppl., S. 1824

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Falkenhorst, Johanna; Mühlenberg, Thomas; Simon, Susanne; Ecken, Sonja; Henze, Jörn; Grabellus, Florian; Breitenbücher, Frank; Schuler, Martin; Fletcher, Jonathan A.; Bauer, Sebastian

Inhibitors of apoptosis (IAPs) in gastrointestinal stromal tumors

In: Cancer Research Jg. 72 (2012) Nr. 8, Suppl., S. 3855 - 3855

ISSN: 1538-7445; 0008-5472

Online Volltext: dx.doi.org/
Schuler, Martin; Yang, James Chih-Hsin; Yamamoto, Nobuyuki; O’Byrne, Ken; Hirsh, Vera; Mok, Tony; Massey, Dan; Zazulina, Victoria; Shahidi, Mehdi; Sequist, Lecia

LUX-lung 3 : A randomized, open-label, phase III study of afatinib vs pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harboring EGFR-activating mutations

In: Lung Cancer / Central European Lung Cancer Conference ; Prague, June 24-27, 2012 Jg. 77 (2012) Nr. Suppl. 1, S. S25 - S26

ISSN: 0169-5002; 1872-8332

Online Volltext: dx.doi.org/
Markova, B.; Hahnel, P. S.; Herbertz, S.; Schuler, Martin; Breitenbücher, Frank

Influence of Everolimus and Pemetrexed on Thymidylate Synthase expression as well as on Proliferation and survival of non-small cell ling Cancer Cells

In: Journal of Thoracic Oncology Jg. 5 (2010) Nr. Suppl. 1, S. S56 - S57

ISSN: 1556-0864; 1556-1380

Online Volltext: dx.doi.org/
Hilger, Ralf A.; Köhler, Johannes; Kalkavan, H.; Richly, Heike; Hoffmann, Andreas-Claudius; Heinrichs, D.; Azaouagh, A.; Schuler, Martin; Trarbach, Tanja;

Interpatient pharmacokinetic variability of 5-FU within metastatic and adjuvant colon cancer patients : First results from the West German Cancer Center
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,

In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 173

ISSN: 0378-584X; 1423-0240; 2296-5262; 2296-5270

Online Volltext: dx.doi.org/
Nguyen, B. P.; Grabellus, Florian; Hoiczyk, M.; Täger, Georg; Schuler, Martin; Bauer, Sebastian;

Metastasectomy in patients with GIST in the era of imatinib - improved survival?
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,

In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 108

ISSN: 0378-584X; 1423-0240; 2296-5262; 2296-5270

Online Volltext: dx.doi.org/
Even, A.; Kasper, Stefan; Breitenbucher, F.; Pogorzelski, M.; Hoffarth, S.; Trarbach, Tanja; Schuler, Martin;

Targeting NF-kappa B and PLK-1 to overcome RAS-mediated resistance to anti-EGFR antibody therapy in colorectal cancer
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,

In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 33

ISSN: 0378-584X; 1423-0240; 2296-5270; 2296-5262

Online Volltext: dx.doi.org/

Beiträge in Sammelwerken und Tagungsbänden

Taube, Christian; Schuler, Martin

Apoptosis in the Physiology and Diseases of the Respiratory Tract

In: Apoptosis: Physiology and Pathology / Reed, John; Green, Douglas R. 2011, S. 221 - 230

ISBN: 978-0-521-88656-7

Online Volltext: dx.doi.org/

Poster / Posterbeiträge

Ölschläger, Katrin; Grabellus, Florian; Schnell, Rainer; Geffken, Mareike; Hoiczyk, Mathias; Ahrens, Marit; Podleska, Lars; Täger, Georg; Treckmann, Jürgen-Walter; Pöttgen, Christoph; Schuler, Martin; Bauer, Sebastian;

Chemotherapie bei resektablen Weichteilsarkomen mit komplexem Karyotyp : eine Single-Center Analyse
The annual meeting of the German, Austrian and Swiss Society of Haematology and Oncology, 19.-23.10.2013, Stuttgart,

Stuttgart (2013)

ZIM

Zentrum für Informations- und Mediendienste

Personensuche

Personensuche

Prof. Dr. med. Martin Schuler

Funktionen

Direktor/in, Innere Klinik (Tumorforschung)

Aktuelle Veranstaltungen

2023 WS

Vergangene Veranstaltungen (max. 10)

2023 SS

Artikel in Zeitschriften

Vorworte / Nachworte

Abstracts

Beiträge in Sammelwerken und Tagungsbänden

Poster / Posterbeiträge