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Fakultät für Biologie - Molekulare Zellbiologie
Anschrift
Universitätsstraße 5
45141 Essen
45141 Essen
Raum
T03 R01 D33
Telefon
Telefax
E-Mail
Funktionen
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Universitätsprofessor/in, Molekulare Zellbiologie
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
Aktuelle Veranstaltungen
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SoSe 2025
- Praktikum Chemie für Lehramtsstudierende
- (Einführung in die) Molekularbiologie
- Übung Molekulare Zellbiologie für Molekularbiologen
- (Einführung in die) Molekularbiologie (MolBio Bs.c. und Bio B.Sc.); Einführung in die molekulare Zellbiologie
- Applied Molecular Biology
- Applied Molecular Biology
- Zell- und Molekularbiologie
- Methods in Cancer Research
Vergangene Veranstaltungen (max. 10)
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WiSe 2024
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Allgemeine Methoden in der Molekularbiologie
- Einführung in die Molekularbiologie (für Molekularbiologen - BA 1. Sem)
- Zell- und Molekularbiologie
- Allgemeine Methoden (Bachelor Bio)
- Molecular Cell Biology
- Übung zur Einführung in die Molekularbiologie
- Allgemeine Methoden Praktikum (Bachelor Bio); Priorität für G1 oder G2
- Molekulare Zellbiologie
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SoSe 2024
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Cdc42 activity in the trailing edge is required for persistent directional migration of keratinocytesIn: Molecular Biology of the Cell , Jg. 35 2023, Nr. 1, br1DOI (Open Access)
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Direct investigation of cell contraction signal networks by light-based perturbation methodsIn: Pflügers Archiv: European Journal of Physiology , Jg. 475 2023, Nr. 12, S. 1439 – 1452
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Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cyclesIn: Nature Communications , Jg. 14 2023, Nr. 1, 8356DOI (Open Access)
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Monitoring the Response of Multiple Signal Network Components to Acute Chemo-Optogenetic Perturbations in Living CellsIn: ChemBioChem , Jg. 23 2022, Nr. 4, e202100582DOI (Open Access)
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The Taspase1/Myosin1f-axis regulates filopodia dynamicsIn: iScience , Jg. 25 2022, Nr. 6, 104355DOI, Online Volltext (Open Access)
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisIn: Cell Reports , Jg. 37 2021, Nr. 8, 110056DOI, Online Volltext (Open Access)
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Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal NetworkIn: Cell Reports , Jg. 33 2020, Nr. 9, S. 108467DOI (Open Access)
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Exploratory cell dynamics : A sense of touch for cells?In: Biological Chemistry , Jg. 399 2018, Nr. 8, S. 809 – 819DOI (Open Access)
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An excitable Rho GTPase signaling network generates dynamic subcellular contraction patternsIn: The Journal of Cell Biology (JCB) , Jg. 216 2017, Nr. 12, S. 4271 – 4285DOI (Open Access)
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Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 ExpressionIn: PLoS ONE , Jg. 10 2015, Nr. 9, S. e0137043DOI (Open Access)
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Everolimus Prevents Podocyte Injury Via Stabilizing Tubb2b And Dcdc2 ExpressionIn: Pediatric Nephrology , Jg. 29 2014, Nr. 9, S. 1674 – 1674
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FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibersIn: Journal of Cell Science , Jg. 127 2014, Nr. 7, S. 1379 – 1393DOI (Open Access)
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Differential expression of cytoskeletal-associated genes in human podocytes by the mTOR inhibitor everolimusIn: Pediatric Nephrology , Jg. 28 2013, Nr. 8, S. 1438 – 1438
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Protective effects of the mTOR inhibitor everolimus on cytoskeletal injury in human podocytes are mediated by RhoA signalingIn: PLoS ONE , Jg. 8 2013, Nr. 2, S. e55980DOI, Online Volltext (Open Access)
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Calcium phosphate nanoparticles as versatile carrier for small and large molecules across cell membranesIn: Journal of Nanoparticle Research , Jg. 14 2012, Nr. 6, 0910
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Protective effects of everolimus on puromycin-induced cytoskeletal alterations in human podocytes are mediated by RhoA-signallingIn: Pediatric Nephrology , Jg. 27 2012, Nr. 9, S. 1638 – 1638
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Coordination of Rho GTPase activities during cell protrusionIn: Nature , Jg. 461 2009, Nr. 7260, S. 99 – 103
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Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edgeIn: Molecular Biology of the Cell , Jg. 20 2009, Nr. 18, S. 4070 – 4082
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RhoA GTPase activation by TLR2 and TLR3 ligands: Connecting via Src to NF-κBIn: The Journal of Immunology (JI) , Jg. 182 2009, Nr. 6, S. 3522 – 3529
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3GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoAIn: Molecular Biology of the Cell , Jg. 19 2008, Nr. 5, S. 2147 – 2153
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Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?In: Trends in Cell Biology , Jg. 18 2008, Nr. 5, S. 210 – 219
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Processing of naturally occurring sense/antisense transcripts of the vertebrate Slc34a gene into short RNAsIn: Physiological Genomics , Jg. 34 2008, Nr. 1, S. 95 – 100
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PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motilityIn: The Journal of Cell Biology (JCB) , Jg. 180 2008, Nr. 1, S. 187 – 203
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Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cellsIn: Journal of Cell Science , Jg. 120 2007, Nr. 19, S. 3465 – 3474
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GEF-H1 Modulates Localized RhoA Activation during Cytokinesis under the Control of Mitotic KinasesIn: Developmental Cell , Jg. 12 2007, Nr. 5, S. 699 – 712DOI (Open Access)
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Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cellsIn: The Journal of Cell Biology (JCB) , Jg. 179 2007, Nr. 3, S. 403 – 410
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Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil functionIn: Journal of Leukocyte Biology , Jg. 81 2007, Nr. 4, S. 1127 – 1136
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Visualizing TLR2- and TLR3-dependent RhoA activation by fret biosensorIn: Journal of Leukocyte Biology 2007, Nr. Supplement, S. 36 – 36
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A microtubule-based, dynein-dependent force induces local cell protrusions: Implications for neurite initiationIn: Brain Cell Biology , Jg. 35 2006, Nr. 1, S. 39 – 56
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Imaging and photobleach correction of Mero-CBD, sensor of endogenous Cdc42 activationIn: Methods in Enzymology , Jg. 406 2006, Nr. 12, S. 140 – 156
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Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar developmentIn: Molecular and Cellular Neuroscience (MCN) , Jg. 33 2006, Nr. 2, S. 109 – 125
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Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein β-catenin with the scaffolding protein MAGI-2In: The Journal of Biological Chemistry (JBC) , Jg. 280 2005, Nr. 7, S. 5676 – 5681
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Activation of endogenous Cdc42 visualized in living cellsIn: Science , Jg. 305 2004, Nr. 5690, S. 1615 – 1619
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Single-Molecule Study of Protein-Protein Interaction Dynamics in a Cell Signaling SystemIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry , Jg. 108 2004, Nr. 2, S. 737 – 744
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Characterization of a type IIb sodium-phosphate cotransporter from zebrafish (Danio rerio) kidneyIn: American Journal of Physiology - Renal Physiology , Jg. 284 2003, Nr. 4, S. F727 – F736
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Single-molecule protein-protein interaction dynamics of GTP-binding protein Cdc42 with downstream effector WASPIn: Biophysical Journal , Jg. 84 2003, Nr. Suppl 2 Pt 2, S. 485a
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Facile synthesis of thiol-reactive Cy3 and Cy5 derivatives with enhanced water solubilityIn: Bioconjugate Chemistry , Jg. 13 2002, Nr. 3, S. 387 – 391
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Regulation of the NPT gene by a naturally occurring antisense transcriptIn: Cell Biochemistry and Biophysics , Jg. 36 2002, Nr. 2/3, S. 241 – 252
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Functional characterization of a Na+-phosphate cotransporter (NaP(i)-II) from zebrafish and identification of related transcriptsIn: Journal of Physiology , Jg. 520 1999, Nr. 1, S. 79 – 89
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Na+-dependent phosphate cotransporters : The NaPi protein familiesIn: The Journal of Experimental Biology , Jg. 201 1998, Nr. 23, S. 3135 – 3142
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Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasion2025DOI (Open Access)
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Role of IFNγ-induced tumor-T cell equilibrium in melanoma latencyIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) , Jg. 21 2023, Nr. S4, Special Issue: Abstractband anlässlich des 33. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 06.–09. September 2023 Hamburg, S. 34DOI (Open Access)
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Signale in wandernden Zellen : Direkte Beobachtungen durch Fluoreszenzmikroskope
Die kleine Form, 20. Mai 2009, Essen,2009 (Die kleine Form 2009)