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Fakultät für Chemie

Raum
S05 V03 F41

Funktionen

  • Universitätsprofessor/in, Umweltmikrobiologie und Biotechnologie

  • Gruppe der Professorinnen und Professoren, Prüfungsausschuss B.Sc./M.Sc.-Studiengang Water Science

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Ninck, Sabrina; Klaus, Thomas; Kochetkova, Tatiana V.; Esser, Sarah P.; Sewald, Leonard; Kaschani, Farnusch; Bräsen, Christopher; Probst, Alexander J.; Kublanov, Ilya V.; Siebers, Bettina; Kaiser, Markus
    Environmental activity-based protein profiling for function-driven enzyme discovery from natural communities
    In: Environmental Microbiomes Jg. 19 (2024) Nr. 1, 36
  • Cowan, D.A.; Albers, S.V.; Antranikian, G.; Atomi, H.; Averhoff, B.; Basen, M.; Driessen, A.J.M.; Jebbar, M.; Kelman, Z.; Kerou, M.; Littlechild, J.; Müller, V.; Schönheit, P.; Siebers, B.; Vorgias, K.
    Extremophiles in a changing world
    In: Extremophiles Jg. 28 (2024) Nr. 2, 26
  • Bost, Jan; Recalde, Alejandra; Waßmer, Bianca; Wagner, Alexander; Siebers, Bettina; Albers, Sonja-Verena
    Application of the endogenous CRISPR-Cas type I-D system for genetic engineering in the thermoacidophilic archaeon Sulfolobus acidocaldarius
    In: Frontiers in Microbiology Jg. 14 (2023) 1254891
  • De Rose, Simone A.; Isupov, Michail N.; Worthy, Harley L.; Stracke, Christina; Harmer, Nicholas J.; Siebers, Bettina; Littlechild, Jennifer A.
    Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus
    In: Frontiers in Microbiology Jg. 14 (2023) 1267570
  • Klaus, Thomas; Ninck, Sabrina; Albersmeier, Andreas; Busche, Tobias; Wibberg, Daniel; Jiang, Jianbing; Elcheninov, Alexander G.; Zayulina, Kseniya S.; Kaschani, Farnusch; Bräsen, Christopher; Overkleeft, Herman S.; Kalinowski, Jörn; Kublanov, Ilya V.; Kaiser, Markus; Siebers, Bettina
    Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1E
    In: Frontiers in Microbiology Jg. 12 (2022) 734039
  • Schmerling, Christian; Kouril, Theresa; Snoep, Jacky; Bräsen, Christopher; Siebers, Bettina
    Enhanced underground metabolism challenges life at high temperature–metabolic thermoadaptation in hyperthermophilic Archaea
    In: Current Opinion in Systems Biology Jg. 30 (2022) 100423
  • Schmerling, Christian; Sewald, Leonard; Heilmann, Geronimo; Witfeld, Frederick; Begerow, Dominik; Jensen, Kenneth; Bräsen, Christopher; Kaschani, Farnusch; Overkleeft, Herman S.; Siebers, Bettina; Kaiser, Markus
    Erratum: Author Correction: Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling (Communications biology (2022) 5 1 (1254))
    In: Communications Biology Jg. 5 (2022) Nr. 1, S. 1319
  • Kuschmierz, Laura; Meyer, Martin; Bräsen, Christopher; Wingender, Jost; Schmitz, Oliver J.; Siebers, Bettina
    Exopolysaccharide composition and size in Sulfolobus acidocaldarius biofilms
    In: Frontiers in Microbiology Jg. 13 (2022) 982745
  • Schmerling, Christian; Sewald, Leonard; Heilmann, Geronimo; Witfeld, Frederick; Begerow, Dominik; Jensen, Kenneth; Bräsen, Christopher; Kaschani, Farnusch; Overkleeft, Herman S.; Siebers, Bettina; Kaiser, Markus
    Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling
    In: Communications Biology Jg. 5 (2022) Nr. 1, 1254
  • Alharbi, Faisal; Knura, Thomas; Siebers, Bettina; Ma, Kesen
    Thermostable and O2-Insensitive Pyruvate Decarboxylases from Thermoacidophilic Archaea Catalyzing the Production of Acetaldehyde
    In: Biology Jg. 11 (2022) Nr. 8, 1247
  • Kuschmierz, Laura; Shen, Lu; Bräsen, Christopher; Snoep, Jacky; Siebers, Bettina
    Workflows for optimization of enzyme cascades and whole cell catalysis based on enzyme kinetic characterization and pathway modelling
    In: Current Opinion in Biotechnology Jg. 74 (2022) S. 55 - 60
  • Benninghoff, Jens C.; Kuschmierz, Laura; Zhou, Xiaoxiao; Albersmeier, Andreas; Pham, Trong Khoa; Busche, Tobias; Wright, Phillip C.; Kalinowski, Jörn; Makarova, Kira S.; Bräsen, Christopher; Flemming, Hans-Curt; Wingender, Jost; Siebers, Bettina
    Exposure to 1-Butanol Exemplifies the Response of the Thermoacidophilic Archaeon Sulfolobus acidocaldarius to Solvent Stress
    In: Applied and Environmental Microbiology Jg. 87 (2021) Nr. 11,
  • Lewis, April M; Recalde, Alejandra; Bräsen, Christopher; Counts, James A; Nussbaum, Phillip; Bost, Jan; Schocke, Larissa; Shen, Lu; Willard, Daniel J; Quax, Tessa E. F; Peeters, Eveline; Siebers, Bettina; Albers, Sonja-Verena; Kelly, Robert M
    The biology of thermoacidophilic archaea from the order Sulfolobales
    In: FEMS Microbiology Reviews Jg. 45 (2021) Nr. 4, fuaa063
  • Wolf, Jacqueline; Koblitz, Julia; Albersmeier, Andreas; Kalinowski, Jörn; Siebers, Bettina; Schomburg, Dietmar; Neumann-Schaal, Meina
    Utilization of Phenol as Carbon Source by the Thermoacidophilic Archaeon Saccharolobus solfataricus P2 Is Limited by Oxygen Supply and the Cellular Stress Response
    In: Frontiers in Microbiology Jg. 11 (2021) S. 587032
  • Shen, Lu; Kohlhaas, Martha; Enoki, Junichi; Meier, Roland; Schönenberger, Bernhard; Wohlgemuth, Roland; Kourist, Robert; Niemeyer, Felix; van Niekerk, David; Bräsen, Christopher; Niemeyer, Jochen; Snoep, Jacky; Siebers, Bettina
    A combined experimental and modelling approach for the Weimberg pathway optimisation
    In: Nature Communications Jg. 11 (2020) Nr. 1, S. 1098
  • Sutiono, Samuel; Siebers, Bettina; Sieber, Volker
    Characterization of highly active 2-keto-3-deoxy-L-arabinonate and 2-keto-3-deoxy-D-xylonate dehydratases in terms of the biotransformation of hemicellulose sugars to chemicals
    In: Applied Microbiology and Biotechnology Jg. 104 (2020) Nr. 16, S. 7023 - 7035
  • Krevet, Sabine; Shen, Lu; Bohnen, Timon; Schoenenberger, Bernhard; Meier, Roland; Obkircher, Markus; Bangert, Klara; Koehling, Rudolf; Allenspach, Eric; Wohlgemuth, Roland; Siebers, Bettina; Bräsen, Christopher
    Corrigendum: Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphogluconate-Dehydratase From Caulobacter crescentus (Frontiers in Bioengineering and Biotechnology, (2020), 8, 10.3389/fbioe.2020.00185)
    In: Frontiers in Bioengineering and Biotechnology Jg. 8 (2020) S. 761
  • Krevet, Sabine; Shen, Lu; Bohnen, Timon; Schoenenberger, Bernhard; Meier, Roland; Obkircher, Markus; Bangert, Klara; Koehling, Rudolf; Allenspach, Eric; Siebers, Bettina; Bräsen, Christopher
    Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphogluconate-Dehydratase From Caulobacter crescentus
    In: Frontiers in Bioengineering and Biotechnology Jg. 8 (2020) S. 185
  • van der Kolk, Nienke; Wagner, Alexander; Wagner, Michaela; Waßmer, Bianca; Siebers, Bettina; Albers, Sonja-Verena
    Identification of XylR, the Activator of Arabinose/Xylose Inducible Regulon in Sulfolobus acidocaldarius and Its Application for Homologous Protein Expression
    In: Frontiers in Microbiology Jg. 11 (2020) S. 1066
  • Tjaden, Britta; Baum, Katharina; Marquardt, Viktoria; Simon, Mareike; Trajkovic-Arsic, Marija; Kouril, Theresa; Siebers, Bettina; Lisec, Jan; Siveke, Jens; Schulte, Johannes H.; Benary, Uwe; Remke, Marc; Wolf, Jana; Schramm, Alexander
    N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma
    In: Scientific Reports Jg. 10 (2020) Nr. 1, S. 7157
  • Maklad, Hassan R.; Gutierrez, Gustavo J.; Esser, Dominik; Siebers, Bettina; Peeters, Eveline
    Phosphorylation of the acyl-CoA binding pocket of the FadR transcription regulator in Sulfolobus acidocaldarius
    In: Biochimie Jg. 175 (2020) S. 120 - 124
  • Stracke, Christina; Meyer, Benjamin; Hagemann, Anna; Jo, Eunhye; Lee, Areum; Albers, Sonja-Verena; Cha, Jaeho; Bräsen, Christopher; Siebers, Bettina
    Salt Stress Response of Sulfolobus acidocaldarius Involves Complex Trehalose Metabolism Utilizing a Novel Trehalose-6-Phosphate Synthase (TPS)/Trehalose-6-Phosphate Phosphatase (TPP) Pathway
    In: Applied and Environmental Microbiology Jg. 86 (2020) Nr. 24, S. e01565 - 20
  • Wang, Kun; Sybers, David; Maklad, Hassan Ramadan; Lemmens, Liesbeth; Lewyllie, Charlotte; Zhou, Xiaoxiao; Schult, Frank; Bräsen, Christopher; Siebers, Bettina; Valegård, Karin; Lindås, Ann-Christin; Peeters, Eveline
    A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
    In: Nature Communications Jg. 10 (2019) Nr. 1, S. 1542
  • Bischof, Lisa F.; Haurat, M. Florencia; Hoffmann, Lena; Albersmeier, Andreas; Wolf, Jacqueline; Neu, Astrid; Pham, Trong Khoa; Albaum, Stefan P.; Jakobi, Tobias; Schouten, Stefan; Neumann-Schaal, Meina; Wright, Phillip C.; Kalinowski, Jörn; Siebers, Bettina; Albers, Sonja-Verena
    Early Response of Sulfolobus acidocaldarius to Nutrient Limitation
    In: Frontiers in Microbiology Jg. 9 (2019) S. 3201
  • Haferkamp, Patrick; Tjaden, Britta; Shen, Lu; Bräsen, Christopher; Kouril, Theresa; Siebers, Bettina
    The Carbon Switch at the Level of Pyruvate and Phosphoenolpyruvate in Sulfolobus solfataricus P2
    In: Frontiers in Microbiology Jg. 10 (2019) S. 757
  • Schocke, Larissa; Bräsen, Christopher; Siebers, Bettina
    Thermoacidophilic Sulfolobus species as source for extremozymes and as novel archaeal platform organisms
    In: Current Opinion in Biotechnology Jg. 59 (2019) S. 71 - 77
  • Wohlgemuth, Roland; Littlechild, Jennifer; Monti, Daniela; Schnorr, Kirk; van Rossum, Teunke; Siebers, Bettina; Menzel, Peter; Kublanov, Ilya V.; Rike, Anne Gunn; Skretas, Georgios; Szabo, Zalan; Peng, Xu; Young, Mark J.
    Discovering novel hydrolases from hot environments
    In: Biotechnology Advances Jg. 36 (2018) Nr. 8, S. 2077 - 2100
  • Schult, Frank; Le, Thuong N.; Albersmeier, Andreas; Rauch, Bernadette; Blumenkamp, Patrick; Van Der Does, Chris; Goesmann, Alexander; Kalinowski, Jörn; Albers, Sonja-Verena; Siebers, Bettina
    Effect of UV irradiation on Sulfolobus acidocaldarius and involvement of the general transcription factor TFB3 in the early UV response
    In: Nucleic Acids Research Jg. 46 (2018) Nr. 14, S. 7179 - 7192
  • Knüppel, Robert; Christensen, Regitse H; Gray, Fiona C; Esser, Dominik; Strauß, Daniela; Medenbach, Jan; Siebers, Bettina; MacNeill, Stuart A; LaRonde, Nicole; Ferreira-Cerca, Sébastien
    Insights into the evolutionary conserved regulation of Rio ATPase activity.
    In: Nucleic Acids Research Jg. 46 (2018) Nr. 3, S. 1441 - 1456
  • Wagner, Michaela; Shen, Lu; Albersmeier, Andreas; van der Kolk, Nienke; Kim, Sujin; Cha, Jaeho; Bräsen, Christopher; Kalinowski, Jörn; Siebers, Bettina; Albers, Sonja-Verena
    Sulfolobus acidocaldarius transports pentoses via a carbohydrate uptake transporter 2 (CUT2)-type ABC transporter and metabolizes them through the aldolase-independent Weimberg pathway
    In: Applied and Environmental Microbiology Jg. 84 (2018) Nr. 3, S. e01273 - 17
  • Zweerink, Susanne; Kallnik, Verena; Ninck, Sabrina; Nickel, Sabrina; Verheyen, Julia; Blum, Marcel; Wagner, Alexander; Feldmann, Ingo; Sickmann, Albert; Albers, Sonja-Verena; Bräsen, Christopher; Kaschani, Farnusch; Siebers, Bettina; Kaiser, Markus
    Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic Archaea
    In: Nature Communications Jg. 8 (2017) S. 15352
  • Stark, Helge; Wolf, Jacqueline; Albersmeier, Andreas; Pham, Trong K.; Hofmann, Julia D.; Siebers, Bettina; Kalinowski, Jörn; Wright, Phillip C.; Neumann-Schaal, Meina; Schomburg, Dietmar
    Oxidative Stickland reactions in an obligate aerobic organism – amino acid catabolism in the Crenarchaeon Sulfolobus solfataricus
    In: The FEBS Journal Jg. 284 (2017) Nr. 13, S. 2078 - 2095
  • Kouril, Theresa; Eicher, Johann J.; Siebers, Bettina; Snoep, Jacky L.
    Phosphoglycerate kinase acts as a futile cycle at high temperature
    In: Microbiology Jg. 163 (2017) Nr. 11, S. 1604 - 1612
  • Quehenberger, Julian; Shen, Lu; Albers, Sonja-Verena; Siebers, Bettina; Spadiut, Oliver
    Sulfolobus - A potential key organism in future biotechnology
    In: Frontiers in Microbiology Jg. 8 (2017) S. 2474
  • Figueiredo, Ana Sofia; Kouril, Theresa; Esser, Dominik; Haferkamp, Patrick; Wieloch, Patricia; Schomburg, Dietmar; Ruoff, Peter; Siebers, Bettina; Schaber, Jörg
    Systems biology of the modified branched Entner-Doudoroff pathway in Sulfolobus solfataricus
    In: PLoS ONE Jg. 12 (2017) Nr. 7, S. e0180331
  • Zhang, Yanfei; Kouril, Theresa; Snoep, Jacky L.; Siebers, Bettina; Barberis, Matteo; Westerhoff, Hans V.
    The Peculiar Glycolytic Pathway in Hyperthermophylic Archaea : Understanding Its Whims by Experimentation In Silico
    In: International Journal of Molecular Sciences (IJMS) Jg. 18 (2017) Nr. 4, S. 876
  • Wolf, Jacqueline; Stark, Helge; Fafenrot, Katharina; Albersmeier, Andreas; Pham, Trong K.; Müller, Katrin B.; Meyer, Benjamin H.; Hoffmann, Lena; Shen, Lu; Albaum, Stefan P.; Kouril, Theresa; Schmidt-Hohagen, Kerstin; Neumann-Schaal, Meina; Bräsen, Christopher; Kalinowski, Jörn; Wright, Phillip C.; Albers, Sonja-Verena; Schomburg, Dietmar; Siebers, Bettina
    A systems biology approach reveals major metabolic changes in the thermoacidophilic archaeon Sulfolobus solfataricus in response to the carbon source L-fucose versus D-glucose
    In: Molecular Microbiology Jg. 102 (2016) Nr. 5, S. 882 - 908
  • Gavrilov, Sergey N.; Stracke, Christina; Jensen, Kenneth; Menzel, Peter; Kallnik, Verena; Slesarev, Alexei; Sokolova, Tatyana; Zayulina, Kseniya; Bräsen, Christopher; Bonch-Osmolovskaya, Elizaveta A.; Peng, Xu; Kublanov, Ilya V.; Siebers, Bettina
    Isolation and Characterization of the First Xylanolytic Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1 and Its Unusual Multidomain Glycosidase
    In: Frontiers in Microbiology Jg. 7 (2016) S. 00552
  • Siebers, Bettina
    Kohlenhydratstoffwechsel in Archaea–Besonderheiten und Herausforderung : Archaeen-Stoffwechsel
    In: Biospektrum Jg. 22 (2016) Nr. 5, S. 455 - 458
  • Esser, Dominik; Hoffmann, Lena; Pham, Trong Khoa; Bräsen, Christopher; Qiu, Wen; Wright, Phillip C.; Albers, Sonja-Verena; Siebers, Bettina
    Protein phosphorylation and its role in archaeal signal transduction
    In: FEMS Microbiology Reviews Jg. 40 (2016) Nr. 5, S. 625 - 647
  • Epple, Matthias; Kuhn, Hubert; Siebers, Bettina; Rehage, Heinz; Köller, Manfred; Sengstock, Christina
    Silberdotierte Calciumphosphat-Nanopartikel als antibakterielle Wirkstoffe : Synthese, Charakterisierung und biologische Wirkung
    In: Unikate: Berichte aus Forschung und Lehre (2016) Nr. 48: Materials Chain : Forschung aus dem UA Ruhr-Profilschwerpunkt, S. 122 - 127
  • Range, Sven; Hagmeyer, Daniel; Rotan, Olga; Sokolova, Viktoriya; Verheyen, Julia; Siebers, Bettina; Epple, Matthias
    A continuous method to prepare poorly crystalline silver-doped calcium phosphate ceramics with antibacterial properties
    In: RSC Advances Jg. 5 (2015) Nr. 54, S. 43172 - 43177
  • Jachlewski, Silke; Jachlewski, Witold D.; Linne, Uwe; Bräsen, Christopher; Wingender, Jost; Siebers, Bettina
    Isolation of Extracellular Polymeric Substances from Biofilms of the Thermoacidophilic Archaeon Sulfolobus acidocaldarius.
    In: Frontiers in Bioengineering and Biotechnology Jg. 3 (2015) S. 123
  • Nelson-Sathi, Shijulal; Sousa, Filipa L.; Roettger, Mayo; Lozada-Chávez, Nabor; Thiergart, Thorsten; Janssen, Arnold; Bryant, David; Landan, Giddy; Schönheit, Peter; Siebers, Bettina; McInerney, James O.; Martin, William F.
    Origins of major archaeal clades correspond to gene acquisitions from bacteria
    In: Nature Jg. 517 (2015) Nr. 7532, S. 77 - 80
  • Bräsen, Christopher; Esser, D.; Rauch, B.; Siebers, Bettina
    Carbohydrate metabolism in archaea : Current insights into unusual enzymes and pathways and their regulation
    In: JAMA Ophthalmology Jg. 132 (2014) Nr. 3, S. 326 - 331
  • Kallnik, Verena; Bunescu, Alina; Sayer, Christopher; Bräsen, Christopher; Wohlgemuth, Roland; Littlechild, Jennifer Ann; Siebers, Bettina
    Characterization of a phosphotriesterase-like lactonase from the hyperthermoacidophilic crenarchaeon Vulcanisaeta moutnovskia
    In: Journal of Biotechnology (2014) Nr. 190, S. 11 - 17
  • Wagner, Michaela; Wagner, Alexander; Ma, Xiaoqing; Kort, Julia Christin; Ghosh, Abhrajyoti; Rauch, Bernadette; Siebers, Bettina; Albers, Sonja-Verena
    Investigation of the malE promoter and MalR, a positive regulator of the maltose regulon, for an improved expression system in Sulfolobus acidocaldarius
    In: Applied and Environmental Microbiology Jg. 80 (2014) Nr. 3, S. 1072 - 1081
  • Matsubara, Kohei; Köhling, Rudi; Schönenberger, Bernhard; Kouril, Theresa; Esser, Dominik; Bräsen, Christopher; Siebers, Bettina; Wohlgemuth, Roland
    One-step synthesis of 2-keto-3-deoxy-D-gluconate by biocatalytic dehydration of D-gluconate
    In: Journal of Biotechnology Jg. 191 (2014) S. 69 - 77
  • Bräsen, Christopher; Siebers, Bettina
    Systembiologie X-trem : Von der Grundlagenforschung zur Anwendung in hyperthermophilen Archaea
    In: GIT: Labor-Fachzeitschrift (2014) Nr. 12, S. 20 - 23
  • Kort, Julia Christin; Esser, Dominik; Pham, Trong Khoa; Noirel, Josselin; Wright, Phillip C.; Siebers, Bettina
    A cool tool for hot and sour Archaea : Proteomics of Sulfolobus solfataricus
    In: Proteomics Jg. 13 (2013) Nr. 18-19, S. 2831 - 2850
  • Reimann, Julia; Esser, Dominik; Orell, Alvaro; Amman, Fabian; Pham, Trong Khoa; Noirel, Josselin; Lindås, Ann-Christin; Bernander, Rolf; Wright, Phillip C.; Siebers, Bettina; Albers, Sonja-Verena
    Archaeal signal transduction: Impact of protein phosphatase deletions on cell size, motility, and energy metabolism in sulfolobus acidocaldarius
    In: Molecular and Cellular Proteomics (MCP) Jg. 12 (2013) Nr. 12, S. 3908 - 3923
  • Esser, Dominik; Siebers, Bettina
    Atypical protein kinases of the RIO family in archaea
    In: Biochemical Society Transactions Jg. 41 (2013) Nr. 1, S. 399 - 404
  • Kouril, Theresa; Esser, Dominik; Kort, Julia; Westerhoff, Hans V.; Siebers, Bettina; Snoep, Jacky L.
    Intermediate instability at high temperature leads to low pathway efficiency for an in vitro reconstituted system of gluconeogenesis in Sulfolobus solfataricus
    In: The FEBS Journal Jg. 280 (2013) Nr. 18, S. 4666 - 4680
  • Orell, Alvaro; Peeters, Eveline; Vassen, Victoria; Jachlewski, Silke; Schalles, Sven; Siebers, Bettina; Albers, Sonja-Verena
    Lrs14 transcriptional regulators influence biofilm formation and cell motility of Crenarchaea
    In: ISME Journal Jg. 7 (2013) S. 1886 - 1898
  • Peetsch, Alexander; Greulich, Christina; Braun, Dieter; Stroetges, Christian; Rehage, Heinz; Siebers, Bettina; Köller, Manfred; Epple, Matthias
    Silver-doped calcium phosphate nanoparticles : Synthesis, characterization, and toxic effects toward mammalian and prokaryotic cells
    In: Colloids and Surfaces B: Biointerfaces (2013) Nr. 102, S. 724 - 729
  • Zaparty, Melanie; Hagemann, Anna; Bräsen, Christopher; Hensel, Reinhard; Lupas, Andrei N.; Brinkmann, Henner; Siebers, Bettina
    The First Prokaryotic Trehalose Synthase Complex Identified in the Hyperthermophilic Crenarchaeon Thermoproteus tenax
    In: PLoS ONE Jg. 8 (2013) Nr. 4, S. e61354
  • Esser, Dominik; Kouril, Theresa; Talfournier, François; Polkowska, Jolanta; Schrader, Thomas; Bräsen, Christopher; Siebers, Bettina
    Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus
    In: Extremophiles Jg. 17 (2013) Nr. 2, S. 205 - 216
  • Kouril, Theresa; Wieloch, Patricia; Reimann, Julia; Wagner, Michaela; Zaparty, Melanie; Albers, Sonja-Verena; Schomburg, Dietmar; Ruoff, Peter; Siebers, Bettina
    Unraveling the function of the two Entner-Doudoroff branches in the thermoacidophilic Crenarchaeon Sulfolobus solfataricus P2
    In: The FEBS Journal Jg. 280 (2013) Nr. 4, S. 1126 - 1138
  • Esser, Dominik; Pham, Trong Khoa; Reimann, Julia; Albers, Sonja-Verena; Siebers, Bettina; Wright, Phillip Craig
    Change of carbon source causes dramatic effects in the phospho-proteome of the archaeon Sulfolobus solfataricus
    In: Journal of Proteome Research Jg. 11 (2012) Nr. 10, S. 4823 - 4833
  • Koerdt, Andrea; Jachlewski, Silke; Ghosh, Anupama; Wingender, Jost; Siebers, Bettina; Albers, Sonja-Verena
    Complementation of Sulfolobus solfataricus PBL2025 with an α-mannosidase : effects on surface attachment and biofilm formation
    In: Extremophiles Jg. 16 (2012) Nr. 1, S. 115 - 125
  • Ulas, Thomas; Riemer, S. Alexander; Zaparty, Melanie; Siebers, Bettina; Schomburg, Dietmar
    Genome-scale reconstruction and analysis of the metabolic network in the hyperthermophilic archaeon Sulfolobus solfataricus.
    In: PLoS ONE Jg. 7 (2012) Nr. 8, S. e43401
  • Greulich, Christina; Braun, Dieter; Peetsch, Alexander; Diendorf, Jörg; Siebers, Bettina; Epple, Matthias; Köller, Manfred
    The toxic effect of silver ions and silver nanoparticles towards bacteria and human cells occurs in the same concentration range
    In: RSC Advances Jg. 2 (2012) Nr. 17, S. 6981 - 6987
  • Haferkamp, Patrick; Kutschki, Simone; Treichel, Jenny; Hemeda, Hatim; Sewczyk, Karsten; Hoffmann, Daniel; Zaparty, Melanie; Siebers, Bettina
    An additional glucose dehydrogenase from Sulfolobus solfataricus : fine-tuning of sugar degradation?
    In: Biochemical Society Transactions Jg. 39 (2011) Nr. 1, S. 77 - 81
  • Marrero, Jeannette; Ehrenhofer-Murray, Ann; Pons, Tirso; Siebers, Bettina
    Functional analysis of archaeal MBF1 by complementation studies in yeast
    In: Biology Direct (2011) Nr. 6, S. 18
  • Esser, Dominik; Kouril, Theresa; Zaparty, Melanie; Sierocinski, Pawel; Chan, Patricia P.; Lowe, Todd; van der Oost, John; Albers, Sonja-Verena; Schomburg, Dietmar; Makarova, Kira S.; Siebers, Bettina
    Functional curation of the Sulfolobus solfataricus P2 and S. acidocaldarius 98-3 complete genome sequences
    In: Extremophiles Jg. 15 (2011) Nr. 6, S. 711 - 712
  • Zaparty, Melanie; Siebers, Bettina
    Manche mögen's heiß — und sauer! : Zuckerabbau in Sulfolobus solfataricus
    In: Biospektrum Jg. 17 (2011) Nr. 1, S. 20 - 23
  • Siebers, Bettina; Zaparty, Melanie; Raddatz, Guenter; Tjaden, Britta; Albers, Sonja-Verena; Bell, Steven D.; Blombach, Fabian; Kletzin, Arnulf; Kyrpides, Nikos; Lanz, Christa; Plagens, Andre; Ramp, Markus; Rosinus, Andrea; von Jan, Matthias; Makarova, Kira S.; Klenk, Hans-Peter; Schuster, Stephan C.; Hensel, Reinhard
    The Complete Genome Sequence of Thermoproteus tenax : A Physiologically Versatile Member of the Crenarchaeota
    In: PLoS ONE Jg. 6 (2011) Nr. 10, S. e24222
  • Zaparty, Melanie; Esser, Dominik; Gertig, Susanne; Haferkamp, Patrick; Kouril, Theresa; Manica, Andrea; Pham, Trong Khoa; Reimann, Julia; Schreiber, Kerstin; Sierocinski, Pawel; Teichmann, Daniela; van Wolferen, Marleen; von Jan, Matthias; Wieloch, Patricia; Albers, Sonja-Verena; Driessen, A. J.; Klenk, Hans-Peter; Schleper, Christa; Schomburg, Dietmar; van der Oost, John; Wright, Phillip Craig; Siebers, Bettina
    “Hot standards” for the thermoacidophilic archaeon Sulfolobus solfataricus
    In: Extremophiles Jg. 14 (2010) Nr. 1, S. 119 - 142
  • Blombach, Fabian; Makarova, Kira S.; Marrero, Jeannette; Siebers, Bettina; Koonin, Eugena V.; van der Oost, John
    Identification of an ortholog of the eukaryotic RNA polymerase III subunit RPC34 in Crenarchaeota and Thaumarchaeota suggests specialization of RNA polymerases for coding and non-coding RNAs in Archaea
    In: Biology Direct Jg. 4 (2009) S. 39
  • Albers, Sonja-Verena; Birkeland, Nils-Kåre; Driessen, Arnold J.M.; Gertig, Susanne; Haferkamp, Patrick; Klenk, Hans-Peter; Kouril, Theresa; Manica, Andrea; Pham, Trong K.; Ruoff, Peter; Schleper, Christa; Schomburg, Dietmar; Sharkey, Kieran J.; Siebers, Bettina; Sierocinski, Pawel; Steuer, Ralf; van der Oost, John; Westerhoff, Hans V.; Wieloch, Patricia; Wright, Philip C.; Zaparty, Melanie
    SulfoSYS - Sulfolobus Systems Biology : towards a Silicon Cell Model for the central carbohydrate metabolism of the Archaeon Sulfolobus solfataricus under temperature variation.
    In: Biochemical Society Transactions Jg. 37 (2009) Nr. 1, S. 58 - 64
  • Kouril, Theresa; Zaparty, Melanie; Marrero, Jeannette; Brinkmann, Henner; Siebers, Bettina
    A novel trehalose synthesizing pathway in the hyperthermophilic Crenarchaeon Thermoproteus tenax : the unidirectional TreT pathway
    In: Archives of Microbiology Jg. 190 (2008) Nr. 3, S. 355 - 369
  • Paulhuhn, Anuschka; Ahmed, Hatim; Lorentzen, Esben; Buchinger, Sebastian; Schomburg, Dietmar; Siebers, Bettina; Pohl, Ehmke
    Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax
    In: Proteins: Structure, Function and Genetics Jg. 72 (2008) Nr. 1, S. 35 - 43
  • Zaparty, Melanie; Zaigler, Alexander; Stamme, Claudia; Soppa, Jörg; Hensel, Reinhard; Siebers, Bettina
    DNA Microarray Analysis of Central Carbohydrate Metabolism : Glycolytic/Gluconeogenic Carbon Switch in the Hyperthermophilic Crenarchaeum Thermoproteus tenax
    In: Journal of Bacteriology Jg. 190 (2008) Nr. 6, S. 2231 - 2238
  • Zaparty, Melanie; Siebers, Bettina; Hensel, Reinhard; Tjaden, Britta
    The central carbohydrate metabolism of the hyperthermophilic crenarchaeote Thermoproteus tenax : Pathways and insights into their regulation
    In: Archives of Microbiology Jg. 190 (2008) Nr. 3, S. 231 - 245
  • Ettema, Thijs J.G.; Ahmed, Hatim; Geerling, Ans C.M.; van der Oost, John; Siebers, Bettina
    The non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) of Sulfolobus solfataricus : a key-enzyme of the semi-phosphorylative branch of the Entner–Doudoroff pathway
    In: Extremophiles Jg. 12 (2008) Nr. 1, S. 75 - 88
  • Luo, Xiao; Schwarz-Linek, Ulrich; Botting, Catherine H.; Hensel, Reinhard; Siebers, Bettina; White, Malcolm F.
    CC1, a Novel Crenarchaeal DNA Binding Protein
    In: Journal of Bacteriology Jg. 189 (2007) Nr. 2, S. 403 - 409
  • Kehrer, Daniel; Ahmed, Hatim; Brinkmann, Henner; Siebers, Bettina
    Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax : new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes
    In: BMC Genomics Jg. 8 (2007) S. 301 - 318
  • Tjaden, Britta; Plagens, André; Dörr, Christine; Siebers, Bettina; Hensel, Reinhard
    Phosphoenolpyruvate synthetase and pyruvate, phosphate dikinase of Thermoproteus tenax : key pieces in the puzzle of archaeal carbohydrate metabolism
    In: Molecular Microbiology Jg. 60 (2006) Nr. 2, S. 287 - 298
  • Lorentzen, Esben; Siebers, Bettina; Hensel, Reinhard; Pohl, Ehmke
    Mechanism of the Schiff Base Forming Fructose-1,6-bisphosphate Aldolase : Structural Analysis of Reaction Intermediates
    In: Biochemistry Jg. 44 (2005) Nr. 11, S. 4222 - 4229
  • Ahmed, Hatim; Ettema, Thijs J. G.; Tjaden, Britta; Geerling, Ans C. M.; van der Oost, John; Siebers, Bettina
    The semi-phosphorylative Entner-Doudoroff pathway in hyperthermophilic archaea : a re-evaluation
    In: Biochemical Journal Jg. 390 (2005) Nr. 2, S. 529 - 540
  • Siebers, Bettina; Schönheit, Peter
    Unusual pathways and enzymes of central carbohydrate metabolism in Archaea
    In: Current Opinion in Microbiology Jg. 8 (2005) Nr. 6, S. 695 - 705
  • Ahmed, Hatim; Tjaden, Britta; Hensel, Reinhard; Siebers, Bettina
    Embden-Meyerhof-Parnas and Entner-Doudoroff pathways in Thermoproteus tenax : metabolic parallelism or specific adaptation?
    In: Biochemical Society Transactions Jg. 32 (2004) Nr. 2, S. 303 - 304
  • Siebers, Bettina; Tjaden, Britta; Michalke, Klaus; Dörr, Christine; Ahmed, Hatim; Zaparty, Melanie; Gordon, Paul; Sensen, Christoph W.; Zibat, Arne; Klenk, Hans-Peter; Schuster, Stephan C.; Hensel, Reinhard
    Reconstruction of the central carbohydrate metabolism of Thermoproteus tenax by use of genomic and biochemical data
    In: Journal of Bacteriology Jg. 186 (2004) Nr. 7, S. 2179 - 2194
  • Lorentzen, Esben; Siebers, Bettina; Hensel, Reinhard; Pohl, Ehmke
    Structure, function and evolution of the Archaeal class I fructose-1,6-bisphosphate aldolase
    In: Biochemical Society Transactions Jg. 32 (2004) Nr. 2, S. 259 - 263
  • Lorentzen, Esben; Pohl, Ehmke; Zwart, Peter; Stark, Alexander; Russell, Robert B.; Knura, Thomas; Hensel, Reinhard; Siebers, Bettina
    Crystal Structure of an Archaeal Class I Aldolase and the Evolution of (βα)₈ Barrel Proteins
    In: The Journal of Biological Chemistry (JBC) Jg. 278 (2003) Nr. 47, S. 47253 - 47260
  • Dörr, Christine; Zaparty, Melanie; Tjaden, Britta; Brinkmann, Henner; Siebers, Bettina
    The hexokinase of the hyperthermophile Thermoproteus tenax : ATP-dependent hexokinases and ADP-dependent glucokinases, teo alternatives for glucose phosphorylation in Archaea
    In: The Journal of Biological Chemistry (JBC) Jg. 278 (2003) Nr. 21, S. 18744 - 18753
  • Siebers, Bettina; Brinkmann, Henner; Dörr, Christine; Tjaden, Britta; Lilie, Hauke; van der Oost, John; Verhees, Corné H.
    Archaeal Fructose-1,6-bisphosphate Aldolases Constitute a New Family of Archaeal Type Class I Aldolase
    In: The Journal of Biological Chemistry (JBC) Jg. 276 (2001) Nr. 31, S. 28710 - 28718
  • Siebers, Bettina; Hensel, Reinhard
    Pyrophosphate-dependent phosphofructokinase from Thermoproteus tenax
    In: Methods in Enzymology Jg. 331: Hyperthermophilic Enzymes Part B (2001) S. 54 - 62
  • Brunner, Nina A.; Siebers, Bettina; Hensel, Reinhard
    Role of two different glyceraldehyde-3-phosphate dehydrogenases in controlling the reversible Embden–Meyerhof–Parnas pathway in Thermoproteus tenax : regulation on protein and transcript level
    In: Extremophiles Jg. 5 (2001) Nr. 2, S. 101 - 109
  • Walden, Helen; Bell, Graeme S.; Russell, Rupert J. M.; Siebers, Bettina; Hensel, Reinhard; Taylor, Garry L.
    Tiny TIM : A small, tetrameric, hyperthermostable triosephosphate isomerase
    In: Journal of Molecular Biology (JMB) Jg. 306 (2001) Nr. 4, S. 745 - 757
  • Schramm, Alexander; Siebers, Bettina; Tjaden, Britta; Brinkmann, Henner; Hensel, Reinhard
    Pyruvate kinase of the hyperthermophilic crenarchaeote Thermoproteus tenax : Physiological role and phylogenetic aspects
    In: Journal of Bacteriology Jg. 182 (2000) Nr. 7, S. 2001 - 2009
  • Brunner, Nina A.; Brinkmann, Henner; Siebers, Bettina; Hensel, Reinhard
    NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase from Thermoproteus tenax : The first identified archaeal member of the aldehyde dehydrogenase superfamily is a glycolytic enzyme with unusual regulatory properties
    In: The Journal of Biological Chemistry (JBC) Jg. 273 (1998) Nr. 11, S. 6149 - 6156
  • Siebers, Bettina; Klenk, Hans-Peter; Hensel, Reinhard
    PPi-dependent phosphofructokinase from Thermoproteus tenax, an archaeal descendant of an ancient line in phosphofructokinase evolution
    In: Journal of Bacteriology Jg. 180 (1998) Nr. 8, S. 2137 - 2143
  • Siebers, Bettina; Wendisch, Volker F.; Hensel, Reinhard
    Carbohydrate metabolism in Thermoproteus tenax : in vivo utilization of the non-phosphorylative Entner-Doudoroff pathway and characterization of its first enzyme, glucose dehydrogenase
    In: Archives of Microbiology Jg. 168 (1997) Nr. 2, S. 120 - 127
  • Hensel, Reinhard; Matussek, Karl; Michalke, Klaus; Tacke, Lothar; Tindall, Brian J.; Kohlhoff, Michael; Siebers, Bettina; Dielenschneider, Jana
    Sulfophobococcus zilligii gen. nov., spec. nov. : a Novel Hyperthermophilic Archaeum Isolated from Hot Alkaline Springs of Iceland
    In: Systematic and Applied Microbiology Jg. 20 (1997) Nr. 1, S. 102 - 110
  • Hensel, Reinhard; Fabry, Stefan; Biro, Jutta; Bogedain, Christoph; Jakob, Irmgard; Siebers, Bettina
    Glyceraldehyde-3-Phosphate Dehydrogenases from Archaea : Objects for Studying Protein Thermoadaptation
    In: Biocatalysis and Biotransformation Jg. 11 (1994) Nr. 2, S. 151 - 164
  • Siebers, Bettina; Hensel, Reinhard
    Glucose catabolism of the hyperthermophilic archaeum Thermoproteus tenax
    In: FEMS Microbiology Letters Jg. 111 (1993) Nr. 1, S. 1 - 8
  • Liß, Harald; Siebers, Bettina; Weiler, Elmar W.
    Characterization, functional reconstitution and activation by fusicoccin of a Ca2+-ATPase from Corydalis sempervirens pers. Cell suspension cultures
    In: Plant and Cell Physiology Jg. 32 (1991) Nr. 7, S. 1049 - 1056
  • Siebers, Bettina; Gräf, Peter; Weiler, Elmar
    Calcium Fluxes across the Plasma Membrane of Commelina communis L. Assayed in a Cell-Free System
    In: Plant Physiology Jg. 93 (1990) Nr. 3, S. 940 - 947
  • Vorworte / Nachworte

  • Fusco, Salvatore; Siebers, Bettina
    Extreme Biocatalysts : From Basic Research to Biotechnological Applications
    In: International Journal of Molecular Sciences (IJMS) Jg. 25 (2024) Nr. 12, 6492
  • Kourist, Robert; González-Sabín, Javier; Siebers, Bettina; Julsing, Mattijs
    Editorial: Applied Microbiology for Chemical Syntheses
    In: Frontiers in Microbiology Jg. 8 (2017) S. 1931
  • Beiträge in Sammelwerken und Tagungsbänden

  • Höfmann, Svenja; Dziwornu, Promise Akua; Klaus, Thomas; Knura, Thomas; Wohlgemuth, Roland; Bräsen, Christopher; Siebers, Bettina
    Simplified Enzymatic Synthesis of 2-Keto-3-Deoxy-D-Gluconate from D-Gluconate Using the Gluconate Dehydratase from Thermoproteus tenax
    In: Archaea: Methods and Protocols / Ferreira-Cerca, Sébastien (Hrsg.) 2022, S. 351 - 362
  • Benninghoff, J.; Wingender, Jost; Flemming, Hans-Curt; Siebers, Bettina
    Biofilms X-treme : Composition of extracellular polymeric substances and exopolysaccharide synthesis in Archaea
    In: The Perfect Slime: Microbial Extracellular Polymeric Substances (EPS) / Flemming, Hans-Curt; Neu, Thomas; Wingender, Jost (Hrsg.) 2016, S. 301 - 317
  • Albers, Sonja-Verena; Siebers, Bettina
    The Family Sulfolobaceae
    In: The Prokaryotes: Other Major Lineages of Bacteria and The Archaea / Rosenberg, Eugenie; DeLong, Edward F.; Lory, Stephen (Hrsg.) 2014, S. 323 - 346
  • Kouril, Theresa; Kolodkin, Alexey; Zaparty, Melanie; Steuer, Ralf; Ruoff, Peter; Westerhoff, Hans; Snoep, Jacky; Siebers, Bettina; SulfoSYS consortium
    Sulfolobus Systems Biology : cool hot design for metabolic pathways
    In: Systems microbiology: current topics and applications / Wren, Brendan W.; Robertson, Brian D. (Hrsg.) 2012
  • Zaparty, Melanie; Siebers, Bettina
    Physiology, Metabolism, and Enzymology of Thermoacidophiles : Reconstruction of the central carbon metabolic network of thermoacidophilic Archaea
    In: Extremophiles Handbook / Horikoshi, Koki (Hrsg.) 2011, S. 601 - 639
  • Peetsch, Alexander; Kort, Julia; Greulich, Christina; Siebers, Bettina; Köller, Manfred; Epple, Matthias
    Silver ion-doped calcium phosphate nanoparticles for antibacterial application
    In: 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials / 24th European Conference on Biomaterials (EBS), 4-8 September 2011, Dublin, Ireland 2011
  • van der Oost, John; Siebers, Bettina
    The Glycolytic Pathways of Archaea : Evolution By Tinkering
    In: Archaea: Evolution, Physiology, and Molecular Biology / Garrett, Roger A.; Klenk, Hans-Peter (Hrsg.) 2007, Nr. Blackwell, S. 247 - 260
  • Brouns, Stan J.J.; Ettema, Thijs J.G.; Stedman, Kenneth M.; Walther, Jasper; Smidt, Hauke; Snijders, Ambrosius P.L.; Young, Mark; Bernander, Rolf; Wright, Phillip C.; Siebers, Bettina; van der Oost, John
    The hyperthermophilic archaeon Sulfolobus – from exploration and exploitation
    In: Geothermal biology and geochemistry in Yellowstone National Park: proceedings of the Thermal Biology Institute workshop / Biology Institute workshop, Yellowstone National Park, WY, October 2003 / Inskeep, William Parks (Hrsg.) 2005, S. 261 - 276
  • Bücher/Sammelwerke/Tagungsbände

  • Siebers, Bettina; Reinberger, Stefanie
    Kleine Überlebenskünstler für die Biotechnologie : Systembiologie Broschüre des BMBF [Broschüre]
    (2016)