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Prof. Dr. rer. nat. Carsten Jürgen Kirschning

Institut für Medizinische Mikrobiologie am Universitätsklinikum Essen

Anschrift
Hufelandstr. 55
45122 Essen
Telefon
0201/723 1824
E-Mail
Carsten.Kirschning@uk-essen.de

Funktionen

  • Universitätsprofessor/in, Institut für Medizinische Mikrobiologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Dyckhoff-Shen, Susanne; Masouris, Ilias; Islam, Heba; Hammerschmidt, Sven; Angele, Barbara; Marathe, Veena; Buer, Jan; Völk, Stefanie; Pfister, Hans-Walter; Klein, Matthias; Koedel, Uwe; Kirschning, Carsten J.
    Combining antibiotic with anti-TLR2/ TLR13 therapy prevents brain pathology in pneumococcal meningitis
    In: JCI Insight, Jg. 9, 2024, Nr. 6, e165737
    DOI (Open Access)
  • Madel, Rabea J.; Börger, Verena; Dittrich, Robin; Bremer, Michel; Tertel, Tobias; Phuong, Nhi Ngo Thi; Baba, Hideo Andreas; Kordelas, Lambros; Staubach, Simon; Stein, Frank; Haberkant, Per; Hackl, Matthias; Grillari, Regina; Grillari, Johannes; Buer, Jan; Horn, Peter; Westendorf, Astrid; Brandau, Sven; Kirschning, Carsten Jürgen; Giebel, Bernd
    Independent human mesenchymal stromal cell–derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model
    In: Cytotherapy, 2023
    DOI (Open Access)
  • Buys, Willem; Bick, Alexandra; Madel, Rabea J.; Westendorf, Astrid; Buer, Jan; Herbstreit, Frank; Kirschning, Carsten Jürgen; Peters, Jürgen
    Substantial heterogeneity of inflammatory cytokine production and its inhibition by a triple cocktail of toll-like receptor blockers in early sepsis
    In: Frontiers in Immunology, Jg. 14, 2023, 1277033
    DOI, Online Volltext (Open Access)
  • Wyczanska, Maja; Rohling, Jana; Keller, Ursula; Benz, Marcus R.; Kirschning, Carsten; Lange-Sperandio, Bärbel
    TLR2 mediates renal apoptosis in neonatal mice subjected experimentally to obstructive nephropathy
    In: PLoS ONE, Jg. 18, 2023, Nr. 11, e0294142
    DOI (Open Access)
  • Wilk, Camilla; Effenberg, Laura; Abberger, Hanna; Steenpass, Laura; Hansen, Wiebke; Zeschnigk, Michael; Kirschning, Carsten Jürgen; Buer, Jan; Kehrmann, Jan
    CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells
    In: Cellular Immunology, Jg. 371, 2022, 104471
    DOI
  • Bick, Alexandra; Buys, Willem; Engler, Andrea; Madel, Rabea; Atia, Mazen; Faro, Francesca; Westendorf, Astrid; Limmer, Andreas; Buer, Jan; Herbstreit, Frank; Kirschning, Carsten Jürgen; Peters, Jürgen
    Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteria
    In: PLoS ONE, Jg. 17, 2022, Nr. 8, e0273247
    DOI, Online Volltext (Open Access)
  • Yang, Xiaoli; Ali, Shafaqat; Zhao, Manman; Richter, Lisa; Schäfer, Vanessa; Schliehe-Diecks, Julian; Frank, Marian; Qi, Jing; Larsen, Pia-Katharina; Skerra, Jennifer; Islam, Heba; Wachtmeister, Thorsten; Alter, Christina; Huang, Anfei; Bhatia, Sanil; Köhrer, Karl; Kirschning, Carsten Jürgen; Weighardt, Heike; Kalinke, Ulrich; Kalscheuer, Rainer; Uhrberg, Markus; Scheu, Stefanie
    The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway
    In: Frontiers in Immunology, Jg. 13, 2022, 856230
    DOI (Open Access)
  • Teske, Nina C.; Engelen-Lee, Joo-Yeon; Dyckhoff-Shen, Susanne; Pfister, Hans-Walter; Klein, Matthias; van de Beek, Diederik; Kirschning, Carsten Jürgen; Koedel, Uwe; Brouwer, Matthijs C.
    The role of plasminogen activator inhibitor-2 in pneumococcal meningitis
    In: Acta Neuropathologica Communications, Jg. 10, 2022, Nr. 1, 155
    DOI (Open Access)
  • Li, Qian; Wang, Jun; Islam, Heba; Kirschning, Carsten Jürgen; Lu, Hongzhou; Hoffmann, Daniel; Dittmer, Ulf; Lu, Mengji
    Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis
    In: Cell Death and Disease, Jg. 12, 2021, Nr. 1, 34
    DOI, Online Volltext (Open Access)
  • Kibler, Artur; Budeus, Bettina; Homp, Ekaterina; Bronischewski, Kevin; Berg, Victoria; Sellmann, Ludger; Murke, Florian; Heinold, Andreas; Heinemann, Falko M.; Lindemann, Monika; Bekeredjian-Ding, Isabelle; Horn, Peter; Kirschning, Carsten Jürgen; Küppers, Ralf; Seifert, Marc
    Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life
    In: Journal of Experimental Medicine (JEM), Jg. 218, 2021, Nr. 4, S. e20201952
    DOI (Open Access)
  • Kleinertz, Holger; Hepner-Schefczyk, Monika; Ehnert, Sabrina; Claus, Maren; Halbgebauer, Rebecca; Boller, Lea; Huber-Lang, Markus; Cinelli, Paolo; Kirschning, Carsten Jürgen; Flohé, Sascha; Sander, André; Waydhas, Christian; Vonderhagen, Sonja; Jäger, Marcus; Dudda, Marcel; Watzl, Carsten; Flohe, Stefanie
    Circulating growth/differentiation factor 15 is associated with human CD56(bright) natural killer cell dysfunction and nosocomial infection in severe systemic inflammation
    In: eBioMedicine, Jg. 43, 2019, S. 380 – 391
    DOI (Open Access)
  • Heß, Rebecca; Storcksdieck Genannt Bonsmann, Michael; Lapuente, Dennis; Maaske, Andre; Kirschning, Carsten Jürgen; Ruland, Jürgen; Lepenies, Bernd; Hannaman, Drew; Tenbusch, Matthias; Überla, Klaus
    Glycosylation of HIV Env Impacts IgG Subtype Responses to Vaccination
    In: Viruses, Jg. 11, 2019, Nr. 2, S. 153
    DOI (Open Access)
  • Madel, R.; Borger, V.; Bremer, M.; Horn, Peter; Baba, Hideo Andreas; Brandau, Sven; Buer, Jan; Giebel, Bernd; Kirschning, Carsten Jürgen
    MSC-EVS protect mice from graft-versus-host disease pathology in a preparation dependent manner
    In: Cytotherapy, Jg. 21, 2019, Nr. Suppl. 5, S. 57
    DOI
  • Fleming, Viktor; Hu, Xiaoying; Weller, Céline; Weber, Rebekka; Groth, Christopher; Riester, Zeno; Hüser, Laura; Sun, Qian; Nagibin, Vasyl; Kirschning, Carsten Jürgen; Bronte, Vincenzo; Utikal, Jochen; Altevogt, Peter; Umansky, Viktor
    Melanoma extracellular vesicles generate immunosuppressive myeloid cells by upregulating PD-L1 via TLR4 signaling
    In: Cancer Research, Jg. 79, 2019, Nr. 18, S. 4715 – 4728
    DOI (Open Access)
  • Zhang, Ejuan; Ma, Zhiyong; Li, Qian; Yan, Hu; Liu, Jia; Wu, Weimin; Guo, Jiabao; Zhang, Xiaoyong; Kirschning, Carsten Jürgen; Xu, Haifeng; Lang, Philipp A.; Yang, Dongliang; Dittmer, Ulf; Yan, Huimin; Lu, Mengji
    TLR2 stimulation increases cellular metabolism in CD8⁺ T cells and thereby enhances CD8⁺ T cell activation, function, and antiviral activity
    In: The Journal of Immunology (JI), Jg. 203, 2019, Nr. 11, S. 2872 – 2886
    DOI
  • Li, Qian; Yan, Yan; Liu, Jia; Huang, Xuan; Zhang, Xiaoyong; Kirschning, Carsten Jürgen; Xu, Haifeng C.; Lang, Philipp A.; Dittmer, Ulf; Zhang, Ejuan; Lu, Mengji
    Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis
    In: Frontiers in Immunology, Jg. 10, 2019, S. 2191
    DOI, Online Volltext (Open Access)
  • Robak, Oliver H.; Heimesaat, Markus M.; Kruglov, Andrey A.; Prepens, Sandra; Ninnemann, Justus; Gutbier, Birgitt; Reppe, Katrin; Hochrein, Hubertus; Suter, Mark; Kirschning, Carsten Jürgen; Marathe, Veena; Buer, Jan; Hornef, Mathias W.; Schnare, Markus; Schneider, Pascal; Witzenrath, Martin; Bereswill, Stefan; Steinhoff, Ulrich; Suttorp, Norbert; Sander, Leif E.; Chaput, Catherine; Opitz, Bastian
    Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia
    In: The Journal of Clinical Investigation (JCI), Jg. 128, 2018, Nr. 8, S. 3535 – 3545
    DOI (Open Access)
  • Gharun, Kourosh; Senges, Julia; Seidl, Maximilian; Lösslein, Anne; Kolter, Julia; Lohrmann, Florens; Fliegauf, Manfred; Elgizouli, Magdeldin; Alber, Marco; Vavra, Martina; Schachtrup, Kristina; Illert, Anna L; Gilleron, Martine; Kirschning, Carsten Jürgen; Triantafyllopoulou, Antigoni; Henneke, Philipp
    Corrigendum: Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells
    In: EMBO Reports, Jg. 19, 2018, Nr. 12, S. e47190
    DOI, Online Volltext (Open Access)
  • Klein, Johanna C.; Moses, Katrin; Zelinskyy, Gennadiy; Sody, Simon; Buer, Jan; Lang, Stephan; Helfrich, Iris; Dittmer, Ulf; Kirschning, Carsten Jürgen; Brandau, Sven
    Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth
    In: Nature Communications, Jg. 8, 2017, S. 14600
    DOI (Open Access)
  • Krieg, Sandro M; Voigt, Florian; Knuefermann, Pascal; Kirschning, Carsten Jürgen; Plesnila, Nikolaus; Ringel, Florian
    Decreased Secondary Lesion Growth and Attenuated Immune Response after Traumatic Brain Injury in Tlr2/4-/- Mice.
    In: Frontiers in Neurology, Jg. 8, 2017, S. 455
    DOI (Open Access)
  • Stein, Karina; Brand, Stephanie; Jenckel, André; Sigmund, Anna; Chen, Zhijian James; Kirschning, Carsten Jürgen; Kauth, Marion; Heine, Holger
    Endosomal recognition of Lactococcus lactis G121 and its RNA by dendritic cells is key to its allergy-protective effects
    In: The Journal of Allergy and Clinical Immunology, Jg. 139, 2017, Nr. 2, S. 667 – 678.e5
    DOI
  • Gharun, Kourosh; Senges, Julia; Seidl, Maximilian; Lösslein, Anne; Kolter, Julia; Lohrmann, Florens; Fliegauf, Manfred; Elgizouli, Magdeldin; Vavra, Martina; Schachtrup, Kristina; Illert, Anna L; Gilleron, Martine; Kirschning, Carsten Jürgen; Triantafyllopoulou, Antigoni; Henneke, Philipp
    Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells
    In: EMBO Reports, Jg. 18, 2017, Nr. 12, S. 2144 – 2159
    DOI
  • Makkawi, Hasnaa; Hoch, Shifra; Burns, Elia; Hosur, Kavita; Hajishengallis, George; Kirschning, Carsten Jürgen; Nussbaum, Gabriel
    Porphyromonas gingivalis stimulates TLR2-PI3K signaling to escape immune clearance and induce bone resorption independently of MyD88
    In: Frontiers in Cellular and Infection Microbiology, Jg. 7, 2017, S. 359
    DOI (Open Access)
  • Stein, K.; Jenckel, A.; Brand, S.; Sigmund, A.; Kirschning, Carsten Jürgen; Kauth, M.; Heine, H.
    RNA is the key element of the th1-promoting and allergy-protective activation of dendritic cells by the cowshed bacterium lactococcus lactis G121
    In: Allergy, Jg. 72, 2017, Nr. Suppl. 103 SI, S. 93 Abstract 0108
    DOI, Online Volltext (Open Access)
  • Ma, Zhiyong; Liu, Jia; Wu, Weimin; Zhang, Ejuan; Zhang, Xiaoyong; Li, Qian; Zelinskyy, Gennadiy; Buer, Jan; Dittmer, Ulf; Kirschning, Carsten Jürgen; Lu, Mengji
    The IL-1R/TLR signaling pathway is essential for efficient CD8+ T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model
    In: Cellular & Molecular Immunology, Jg. 14, 2017, Nr. 12, S. 997 – 1008
    DOI (Open Access)
  • Schick, Judith; Etschel, Philipp; Bailo, Rebeca; Ott, Lisa; Bhatt, Apoorva; Lepenies, Bernd; Kirschning, Carsten Jürgen; Burkovski, Andreas; Lang, Roland
    Toll-like receptor 2 and Mincle cooperatively sense corynebacterial cell wall glycolipids
    In: Infection and Immunity, Jg. 85, 2017, Nr. 7, S. e00075 – 17
    DOI (Open Access)
  • Lehmann, Michael H.; Torres-Domínguez, Lino E.; Price, Philip J. R.; Brandmüller, Christine; Kirschning, Carsten Jürgen; Sutter, Gerd
    CCL2 expression is mediated by type I IFN receptor and recruits NK and T cells to the lung during MVA infection
    In: Journal of Leukocyte Biology (JLB), Jg. 99, 2016, Nr. 6, S. 1057 – 1064
    DOI
  • Maney, Sathish Kumar; Xu, Haifeng C; Huang, Jun; Pandyra, Aleksandra A; Ehlting, Christian; Aguilar-Valenzuela, Renan; Pozdeev, Vitaly I; McIlwain, David R; Zimmermann, Albert; Bode, Johannes G; Hengel, Hartmut; Kirschning, Carsten Jürgen; Kim, Ira R; Hiscott, John; Brenner, Dirk; Häussinger, Dieter; Ohashi, Pamela S; Mak, Tak W; Lang, Karl S.; Lang, Philipp A
    RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production
    In: Cellular Physiology and Biochemistry, Jg. 39, 2016, Nr. 4, S. 1271 – 1280
    DOI (Open Access)
  • Kaesler, Susanne; Biedermann, Tilo; Röcken, Martin; Kirschning, Carsten Jürgen; Hartung, Thomas; Hein, Ulrike; Wölbing, Florian; Köberle, Martin; Volz, Thomas; Kempf, Wolfgang E.; Chen, Ko-Ming; Skabytska, Yuliya
    Staphylococcus aureus–derived lipoteichoic acid induces temporary T-cell paralysis independent of Toll-like receptor 2
    In: The Journal of Allergy and Clinical Immunology, Jg. 138, 2016, Nr. 3, S. 780 – 790.e6
    DOI
  • Kolter, Julia; Kirschning, Carsten Jürgen; Waskow, Claudia; Goldmann, Tobias; Trieu-Cuot, Patrick; Elling, Roland; Gharun, Kourosh; Spoeri, Evelyne; Feuerstein, Reinhild
    Streptococci Engage TLR13 on Myeloid Cells in a Site-Specific Fashion
    In: The Journal of Immunology (JI), Jg. 196, 2016, Nr. 6, S. 2733 – 2741
    DOI (Open Access)
  • Castiglia, Virginia; Piersigilli, Alessandra; Ebner, Florian; Janos, Marton; Goldmann, Oliver; Damböck, Ursula; Kröger, Andrea; Weiss, Sigfried; Knapp, Sylvia; Jamieson, Amanda M; Kirschning, Carsten Jürgen; Kalinke, Ulrich; Strobl, Birgit; Müller, Mathias; Stoiber, Dagmar; Lienenklaus, Stefan; Kovarik, Pavel
    Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue
    In: Cell Host & Microbe, Jg. 19, 2016, Nr. 3, S. 375 – 387
    DOI (Open Access)
  • Heine, H.; Stein, K.; Jenckel, A.; Brand, S.; Sigmund, A; Holst, O.; Kirschning, Carsten Jürgen; Kauth, M.
    Allergy-protection by the cowshed bacterium Lactococcus lactis G121 involves endosomal acidification and signaling through TLR13 in dendritic cells
    In: Allergy, Jg. 70, 2015, Nr. Suppl. 101, S. 52 – 53
    DOI (Open Access)
  • Khairnar, Vishal; Duhan, Vikas; Kumar Maney, Sathish; Seifert, Marc; Kirschning, Carsten; Westendorf, Astrid M.; Dittmer, Ulf; Küppers, Ralf; Scheffrahn, Inka; Göthert, Joachim R.; Singer, Bernhard B.; Lang, Karl S.; et al.
    CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
    In: Nature Communications, Jg. 6, 2015, 6217
    DOI (Open Access)
  • Krüger, Anne; Oldenburg, Marina; Chebrolu, Chiranjeevi; Beisser, Daniela; Kolter, Julia; Sigmund, Anna M.; Steinmann, Jörg; Schäfer, Simon; Hochrein, Hubertus; Rahmann, Sven; Wagner, Hermann; Henneke, Philipp; Hornung, Veit; Buer, Jan; Kirschning, Carsten Jürgen
    Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
    In: EMBO Reports, Jg. 16, 2015, Nr. 12, S. 1656 – 1663
    DOI (Open Access)
  • Fieber, Christina; Janos, Marton; Koestler, Tina; Gratz, Nina; Li, Xiao-Dong; Castiglia, Virginia; Aberle, Marion; Sauert, Martina; Wegner, Mareike; Alexopoulou, Lena; Kirschning, Carsten Jürgen; Chen, Zhijian J.; Haeseler, Arndt von; Kovarik, Pavel
    Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2
    In: PLoS ONE, Jg. 10, 2015, Nr. 3, S. e0119727
    DOI (Open Access)
  • Chebrolu, Chiranjeevi; Artner, Daniel; Sigmund, Anna M; Buer, Jan; Zamyatina, Alla; Kirschning, Carsten Jürgen
    Species and mediator specific TLR4 antagonism in primary human and murine immune cells by βGlcN(1 ↔ 1)αGlc based lipid A mimetics
    In: Molecular Immunology, Jg. 67, 2015, Nr. 2 B, S. 636 – 641
    DOI
  • Price,, Phillip J. R.; Luckow, Bruno; Torres-Domínguez, Lino E.; Brandmüller, Christine; Zorn, Julia; Kirschning, Carsten Jürgen; Sutter, Gerd; Lehmann, Michael H.
    Chemokine (C-C Motif) Receptor 1 Is Required for Efficient Recruitment of Neutrophils during Respiratory Infection with Modified Vaccinia Virus Ankara
    In: Journal of Virology, Jg. 88, 2014, Nr. 18, S. 10840 – 10850
    DOI, Online Volltext (Open Access)
  • Dankmeyer, Jennifer L.; Fast, Randy L.; Cote, Christopher K.; Worsham, Patricia L.; Fritz, David; Fisher, Diana; Kern, Steven J.; Merkel, Tod; Kirschning, Carsten Jürgen; Amemiya, Kei
    Multiple roles of Myd88 in the immune response to the plague F1-V vaccine and in protection against an aerosol challenge of Yersinia pestis CO92 in mice
    In: Journal of Immunology Research, 2014, S. 341820
    DOI (Open Access)
  • Volz, Thomas; Skabytska, Yuliya; Guenova, Emmanuella; Chen, Ko-Ming; Frick, Julia-Stefanie; Kirschning, Carsten Jürgen; Kaesler, Susanne; Röcken, Martin; Biedermann, Tilo
    Nonpathogenic bacteria alleviating atopic dermatitis inflammation induce IL-10-producing dendritic cells and regulatory Tr1 cells
    In: Journal of Investigative Dermatology, Jg. 134, 2014, Nr. 1, S. 96 – 104
    DOI (Open Access)
  • Knuschke, Torben; Bayer, Wibke; Rotan, Olga; Sokolova, Viktoriya; Wadwa, Munisch; Kirschning, Carsten Jürgen; Hansen, Wiebke; Sparwasser, T.; Dittmer, Ulf; Epple, Matthias; Buer, Jan; Westendorf, Astrid
    Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection
    In: Nanomedicine: Nanotechnology, Biology, and Medicine, Jg. 10, 2014, Nr. 8, S. 1787 – 1798
    DOI
  • Hochrein, Hubertus; Kirschning, Carsten Jürgen
    Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms
    In: OncoImmunology, Jg. 2, 2013, Nr. 3, e23141
    DOI
  • Reimer, Elisa; Somplatzki, Stefan; Zegenhagen, Diana; Hänel, Svenja; Fels, Alina; Bollhorst, Thorsten; Grosse-Hovest, Ludger; Bauer, Stefan; Kirschning, Carsten Jürgen; Böldicke, Thomas
    Molecular cloning and characterization of a novel anti-TLR9 intrabody
    In: Cellular and Molecular Biology Letters, Jg. 18, 2013, Nr. 3, S. 433 – 446
    DOI
  • Muntasell, Aura; Costa-Garcia, Marcel; Vera, Andrea; Marina-Garcia, Noemí; Kirschning, Carsten Jürgen; López-Botet, Miguel
    Priming of NK cell anti-viral effector mechanisms by direct recognition of human cytomegalovirus
    In: Frontiers in Immunology, Jg. 4, 2013, S. 40
    DOI (Open Access)
  • Kerur, Nagaraj; Hirano, Yoshio; Tarallo, Valeria; Fowler, Benjamin J.; Bastos-Carvalho, Ana; Yasuma, Tetsuhiro; Yasuma, Reo; Kim, Younghee; Hinton, David R.; Kirschning, Carsten Jürgen; Gelfand, Bradley D.; Ambati, Jayakrishna
    TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy
    In: Investigative Ophthalmology & Visual Science (IOVS), Jg. 54, 2013, Nr. 12, S. 7395 – 7401
    DOI
  • Desel, Christiane; Werninghaus, Kerstin; Ritter, Manuel; Jozefowski, Katrin; Wenzel, Jens; Russkamp, Norman; Schleicher, Ulrike; Christensen, Dennis; Wirtz, Stefan; Kirschning, Carsten Jürgen; Agger, Else Marie; Prazeres da Costa, Clarissa; Lang, Roland
    The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling
    In: PLoS ONE, Jg. 8, 2013, Nr. 1, S. e53531
    DOI (Open Access)
  • Eigenbrod, Tatjana; Franchi, Luigi; Muñoz-Planillo, Raul; Kirschning, Carsten Jürgen; Freudenberg, Marina A.; Núñez, Gabriel; Dalpke, Alexander
    Bacterial RNA mediates activation of caspase-1 and IL-1β release independently of TLRs 3, 7, 9 and TRIF but is dependent on UNC93B
    In: The Journal of Immunology (JI), Jg. 189, 2012, Nr. 1, S. 328 – 336
    DOI
  • Schwandt, Timo; Schumak, Beatrix; Gielen, Gerrit H.; Jüngerkes, Frank; Schmidbauer, Patricia; Klocke, Katrin; Staratschek-Jox, Andrea; Van Rooijen, Niko; Kraal, Georg; Ludwig-Portugall, Isis; Franken, Lars; Wehner, Sven; Kalff, Jörg C.; Weber, Olaf; Kirschning, Carsten Jürgen; Coch, Christoph; Kalinke, Ulrich; Wenzel, Jörg; Kurts, Christian; Zawatzky, Rainer; Holzmann, Bernhard; Layland, Laura; Schultze, Joachim L.; Burgdorf, Sven; Den Haan, Joke M.M.; Knolle, Percy A.; Limmer, Andreas
    Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis
    In: The EMBO Journal, Jg. 31, 2012, Nr. 1, S. 201 – 213
    DOI
  • Welsch, Janina; Hübschle, Thomas; Murgott, Jolanta; Kirschning, Carsten Jürgen; Rummel, Christoph; Gerstberger, Rüdiger; Roth, Joachim
    Fever induction by systemic stimulation with macrophage-activating lipopeptide-2 depends upon TLR2 but not CD36
    In: Innate Immunity, Jg. 18, 2012, Nr. 3, S. 541 – 559
    DOI
  • Bekeredjian-Ding, Isabelle; Foermer, Sandra; Kirschning, Carsten Jürgen; Parcina, Marijo; Heeg, Klaus
    Poke weed mitogen requires toll-like receptor ligands for proliferative activity in human and murine b lymphocytes
    In: PLoS ONE, Jg. 7, 2012, Nr. 1
    DOI (Open Access)
  • Gamrekelashvili, Jaba; Ormandy, Lars A.; Heimesaat, Markus M.; Kirschning, Carsten Jürgen; Manns, Michael P.; Korangy, Firouzeh; Greten, Tim F.
    Primary sterile necrotic cells fail to cross-prime CD8⁺ T cells
    In: OncoImmunology, Jg. 1, 2012, Nr. 7, S. 1017 – 1026
    DOI
  • Ganal, Stephanie C.; Sanos, Stephanie L.; Kallfass, Carsten; Oberle, Karin; Johner, Caroline; Kirschning, Carsten; Lienenklaus, Stefan; Weiss, Siegfried; Staeheli, Peter; Aichele, Peter; Diefenbach, Andreas
    Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota
    In: Immunity, Jg. 37, 2012, Nr. 1, S. 171 – 186
    DOI
  • Sigmund, Alexander; Dreher, S.; Wagner, H.; Weitkunat, M.; Kirschning, Carsten Jürgen
    TLR- NOX2 interaction-driven oxidative burst
    In: Immunology, Jg. 137, 2012, Nr. Suppl. 1, S. 4 – 4
  • Oldenburg, Marina; Krüger, Anne; Ferstl, Ruth; Kaufmann, Andreas; Nees, Gernot; Sigmund, Anna; Bathke, Barbara; Lauterbach, Henning; Suter, Mark; Dreher, Stefan; Koedel, Uwe; Akira, Shizuo; Kawai, Taro; Buer, Jan; Wagner, Hermann; Bauer, Stefan; Hochrein, Hubertus; Kirschning, Carsten Jürgen
    TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance - Forming modification
    In: Science, Jg. 337, 2012, Nr. 6098, S. 1111 – 1115
    DOI
  • Tchaptchet, Sandrine; Gumenscheimer, Marina; Kalis, Christoph; Freudenberg, Nikolaus; Hölscher, Christoph; Kirschning, Carsten Jürgen; Lamers, Marinus; Galanos, Chris; Freudenberg, Marina A.
    TLR9-dependent and independent pathways drive activation of the immune system by propionibacterium acnes
    In: PLoS ONE, Jg. 7, 2012, Nr. 6, S. e37155
    DOI (Open Access)
  • Hanley, Peter J.; Kronlage, Moritz; Kirschning, Carsten Jürgen; Del Rey, Adriana; Di Virgilio, Francesco; Leipziger, Jens; Chessell, Iain P.; Sargin, Sarah; Filippov, Mikhail A.; Lindemann, Otto; Mohr, Simon; Königs, Volker; Schillers, Hermann; Bähler, Martin; Schwab, Albrecht
    Transient P2X 7 receptor activation triggers macrophage death independent of toll-like receptors 2 and 4, caspase-1, and pannexin-1 proteins
    In: The Journal of Biological Chemistry (JBC), Jg. 287, 2012, Nr. 13, S. 10650 – 10663
    DOI
  • Diefenbach, A.; Sanos, S. L.; Kallfass, C.; Kirschning, Carsten Jürgen; Lienenklaus, S.; Weiss, S.; Staeheli, P.; Aichele, P.; Ganal, S. C.
    Type I interferon gene expression by non-mucosal mononuclear phagocytes requires poising by the commensal microbiota
    In: Immunology, Jg. 137, 2012, Nr. Suppl. 1, S. 245
  • Yakimchuk, Konstantin; Roura-Mir, Carme; Magalhaes, Kelly G.; De Jong, Annemieke; Kasmar, Anne G.; Granter, Scott R.; Budd, Ralph; Steere, Allen; Pena-Cruz, Victor; Kirschning, Carsten Jürgen; Cheng, Tan-Yun; Moody, D. Branch
    Borrelia burgdorferi infection regulates CD1 expression in human cells and tissues via IL1-β
    In: European Journal of Immunology, Jg. 41, 2011, Nr. 3, S. 694 – 705
    DOI (Open Access)
  • Specht, Sabine; Frank, Jutta K.; Alferink, Judith; Dubben, Bettina; Layland, Laura E.; Denece, Gaelle; Bain, Odile; Förster, Irmgard; Kirschning, Carsten Jürgen; Martin, Coralie; Hoerauf, Achim
    CCL17 Controls Mast Cells for the Defense against Filarial Larval Entry
    In: The Journal of Immunology (JI), Jg. 186, 2011, Nr. 8, S. 4845 – 4852
    DOI
  • Lippmann, Juliane; Müller, Holger C.; Naujoks, Jan; Tabeling, Christoph; Shin, Sunny; Witzenrath, Martin; Hellwig, Katharina; Kirschning, Carsten Jürgen; Taylor, Gregory A.; Barchet, Winfried; Bauer, Stefan; Suttorp, Norbert; Roy, Craig R.; Opitz, Bastian
    Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice
    In: Cellular Microbiology, Jg. 13, 2011, Nr. 11, S. 1668 – 1682
    DOI
  • Mersmann, Jan; Habeck, Katharina; Latsch, Kathrina; Zimmermann, René; Jacoby, Christoph; Fischer, Jens W.; Hartmann, Christian; Schrader, Jürgen; Kirschning, Carsten Jürgen; Zacharowski, Kai
    Left ventricular dilation in toll-like receptor 2 deficient mice after myocardial ischemia/reperfusion through defective scar formation
    In: Basic Research in Cardiology, Jg. 106, 2011, Nr. 1, S. 89 – 98
    DOI
  • Hoegen, Tobias; Tremel, Nadin; Klein, Matthias; Angele, Barbara; Wagner, Hermann; Kirschning, Carsten Jürgen; Pfister, Hans-Walter; Fontana, Adriano; Hammerschmidt, Sven; Koedel, Uwe
    The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release
    In: The Journal of Immunology (JI), Jg. 187, 2011, Nr. 10, S. 5440 – 5451
    DOI (Open Access)
  • Kirschning, Carsten Jürgen; Dreher, Stefan; Maaß, Björn; Fichte, Sylvia; Schade, Jutta; Köster, Mario; Noack, Andreas; Lindenmaier, Werner; Wagner, Hermann; Böldicke, Thomas
    Generation of anti-TLR2 intrabody mediating inhibition of macrophage surface TLR2 expression and TLR2-driven cell activation
    In: BMC Biotechnology, Jg. 10, 2010, 31
    DOI (Open Access)
  • Gibbert, Kathrin; Dietze, Kirsten; Zelinskyy, Gennadiy; Lang, Karl S.; Barchet, Winfried; Kirschning, Carsten Jürgen; Dittmer, Ulf
    Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease
    In: The Journal of Immunology (JI), Jg. 185, 2010, Nr. 10, S. 6179 – 6189
    DOI (Open Access)
  • Wang, Shijun; Schmaderer, Christoph; Kiss, Eva; Schmidt, Claudia; Bonrouhi, Mahnaz; Porubsky, Stefan; Gretz, Norbert; Schaefer, Liliana; Kirschning, Carsten Jürgen; Popovic, Zoran V.; Gröne, Hermann-Josef
    Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling
    In: Disease Models and Mechanisms (DMM), Jg. 3, 2010, Nr. 1-2, S. 92 – 103
    DOI
  • Mersmann, Jan; Koch, Alexander; Tran, Nguyen; Zimmermann, René; Granja, Tiago F.; Larmann, Jan; Herzog, Christine; Theilmeier, Gregor; Bornstein, Stefan R.; Kirschning, Carsten Jürgen; Zacharowski, Kai
    Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion
    In: Critical Care Medicine, Jg. 38, 2010, Nr. 10, S. 1927 – 1932
    DOI
  • Baiersdörfer, Markus; Schwarz, Margarethe; Seehafer, K.; Lehmann, Hans-Joachim; Heit, Antje; Wagner, Hermann; Kirschning, Carsten Jürgen; Koch-Brandt, Claudia
    Toll-like receptor 3 mediates expression of clusterin/apolipoprotein J in vascular smooth muscle cells stimulated with RNA released from necrotic cells
    In: Experimental Cell Research, Jg. 316, 2010, Nr. 20, S. 3489 – 3500
    DOI
  • Rusai, Krisztina; Sollinger, Daniel; Baumann, Marcus; Wagner, Bettina; Strobl, Matthias; Schmaderer, Christoph; Roos, Marcel; Kirschning, Carsten Jürgen; Heemann, Uwe; Lutz, Jens
    Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury
    In: Pediatric Nephrology, Jg. 25, 2010, Nr. 5, S. 853 – 860
    DOI

    • Vorworte / Nachworte

  • Meng, Guangxun; Kirschning, Carsten Jürgen; Zhou, Rongbin
    Editorial: Patho- and Physiological Roles of Inflammasomes
    In: Frontiers in Immunology. Lausanne: Frontiers Media, Jg. 13, 2022, 857929
    DOI (Open Access)

    • Abstracts

  • Urbonaviciute, Vilma; Starke, Charlotte; Gräf, Daniela; Mroz, Markus; Kirschning, Carsten; Schett, Georg; Voll, Reinhard E.
    Involvement of toll-like receptor 2 in pristane-induced lupus
    In: Annals of the Rheumatic Diseases (ARD). London: BMJ Publishing Group, Jg. 70, 2011, Nr. Suppl. 2, S. A37 – A38
    DOI
  • Urbonaviciute, V.; Fuernrohr, B. G.; Meister, S.; Munoz, L.; Heyder, P.; De Marchis, F.; Bianchi, M. E.; Kirschning, Carsten Jürgen; Wagner, H.; Manfredi, A. A.; Kalden, J. R.; Schett, G.; Rovere-Querini, P.; Herrmann, M.; Voll, R. E.
    HMGB1 Containing Nucleosomes from Apoptotic Cells Induce Inflammation and Immune Activation via TLR2-Implications for the Etiopathogenesis of Systemic Lupus Erythematosus
    30th European Workshop for Rheumatology Research, 4-7 March 2010, Bamberg, Germany,
    In: Annals of the Rheumatic Diseases (ARD). London: BMJ Publishing Group, Jg. 69, 2010, Nr. Suppl. 2, S. A1
    DOI

    • Poster / Posterbeiträge

  • Yang, Xiaoli; Ali, Shafaqat; Richter, Lisa; Schäfer, Vanessa; Schliehe-Diecks, Julian; Frank, Marian; Larsen, Pia-Katharina; Skerra, Jennifer; Islam, Heba; Wachtmeister, Thorsten; Alter, Christina; Bhatia, Sanil; Köhrer, Karl; Kirschning, Carsten Jürgen; Weighardt, Heike; Kalinke, Ulrich; Kalscheuer, Rainer; Uhrberg, Markus; Scheu, Stefanie
    The mycotoxin Beauvericin exhibits immunostimulatory effects on dendritic cells via activating the TLR4 signaling pathway
    Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology. Hoboken: Wiley, Jg. 53, 2023, Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 35
    DOI (Open Access)
  • Krueger, A.; Oldenburg, M.; Ferstl, R.; Sigmund, A.; Akira, S.; Kawai, T.; Buer, Jan; Wagner, H.; Bauer, S.; Hochrein, H.; Kirschning, Carsten Jürgen
    Neutralization of pathogenic Gram-positive bacteria by macrophages is independent from TLR2,-3,-4,-7, and-9 yet depends upon MyD88
    European Congress of Immunology, 5‐8 September 2012, Glasgow, Scotland,
    In: Immunology. Hoboken: Wiley-Blackwell - STM, Jg. 137, 2012, Nr. Suppl. 1, S. 299 – 299
    DOI